RPL26P37

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.98026374
2chaperone-mediated protein transport (GO:0072321)7.76295767
3translational termination (GO:0006415)7.57969566
4ATP synthesis coupled proton transport (GO:0015986)6.99518572
5energy coupled proton transport, down electrochemical gradient (GO:0015985)6.99518572
6ribosomal small subunit biogenesis (GO:0042274)6.87401564
7maturation of SSU-rRNA (GO:0030490)6.62347498
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.58885549
9ribosomal small subunit assembly (GO:0000028)6.57672165
10translational elongation (GO:0006414)6.57354590
11cotranslational protein targeting to membrane (GO:0006613)6.46519764
12protein targeting to ER (GO:0045047)6.45236756
13establishment of protein localization to endoplasmic reticulum (GO:0072599)6.13564651
14protein localization to endoplasmic reticulum (GO:0070972)6.06620360
15mitochondrial ATP synthesis coupled proton transport (GO:0042776)6.02474717
16viral life cycle (GO:0019058)5.70969055
17cellular protein complex disassembly (GO:0043624)5.60677668
18nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.55580310
19ribosomal large subunit biogenesis (GO:0042273)5.21977747
20tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)5.10259124
21RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)5.10259124
22mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.86834718
23translational initiation (GO:0006413)4.85713728
24respiratory electron transport chain (GO:0022904)4.79284852
25gonadal mesoderm development (GO:0007506)4.74443856
26electron transport chain (GO:0022900)4.71094874
27protein targeting to membrane (GO:0006612)4.70143469
28protein complex disassembly (GO:0043241)4.67344452
29DNA deamination (GO:0045006)4.39181065
30translation (GO:0006412)4.36245876
31macromolecular complex disassembly (GO:0032984)4.34211835
32mitochondrial respiratory chain complex I assembly (GO:0032981)4.12182461
33NADH dehydrogenase complex assembly (GO:0010257)4.12182461
34mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.12182461
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.12030089
36nuclear-transcribed mRNA catabolic process (GO:0000956)4.08817214
37nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.08449658
38ATP biosynthetic process (GO:0006754)4.04236409
39protein neddylation (GO:0045116)3.92464182
40protein complex biogenesis (GO:0070271)3.89452014
41mRNA catabolic process (GO:0006402)3.85540319
42purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.73284046
43cellular component biogenesis (GO:0044085)3.72716611
44purine nucleoside triphosphate biosynthetic process (GO:0009145)3.65036640
45behavioral response to nicotine (GO:0035095)3.62698919
46hydrogen ion transmembrane transport (GO:1902600)3.59732034
47mannose metabolic process (GO:0006013)3.53754619
48RNA catabolic process (GO:0006401)3.52753233
49mitochondrial respiratory chain complex assembly (GO:0033108)3.39967616
50ribonucleoprotein complex biogenesis (GO:0022613)3.39078755
51preassembly of GPI anchor in ER membrane (GO:0016254)3.36046529
52establishment of protein localization to mitochondrial membrane (GO:0090151)3.30835085
53GDP-mannose metabolic process (GO:0019673)3.30575205
54proton transport (GO:0015992)3.22474644
55hydrogen transport (GO:0006818)3.17835180
56establishment of protein localization to membrane (GO:0090150)3.15153476
57ribonucleoside triphosphate biosynthetic process (GO:0009201)3.13662576
58nucleoside transmembrane transport (GO:1901642)3.13133486
59peroxisome fission (GO:0016559)3.11298807
60base-excision repair, AP site formation (GO:0006285)3.09766017
61aldehyde catabolic process (GO:0046185)2.98874809
62protein targeting (GO:0006605)2.98454469
63substrate-independent telencephalic tangential migration (GO:0021826)2.86207677
64substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.86207677
65negative regulation of calcium ion transport into cytosol (GO:0010523)2.86158061
66transcription elongation from RNA polymerase III promoter (GO:0006385)2.85910191
67termination of RNA polymerase III transcription (GO:0006386)2.85910191
68viral protein processing (GO:0019082)2.85713467
69platelet dense granule organization (GO:0060155)2.82780263
70regulation of cellular respiration (GO:0043457)2.80288954
71pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.78466837
72mannosylation (GO:0097502)2.77450723
73intracellular protein transmembrane import (GO:0044743)2.76679863
74interferon-gamma production (GO:0032609)2.76617091
75GTP biosynthetic process (GO:0006183)2.75268231
76neuronal action potential propagation (GO:0019227)2.69258927
77synaptic transmission, cholinergic (GO:0007271)2.67740680
78somite development (GO:0061053)2.66440284
79cell proliferation in forebrain (GO:0021846)2.66099966
80kynurenine metabolic process (GO:0070189)2.65809009
81outer ear morphogenesis (GO:0042473)2.65423362
82negative regulation of mast cell activation (GO:0033004)2.61999045
83nucleoside triphosphate biosynthetic process (GO:0009142)2.60765590
84positive regulation of fatty acid transport (GO:2000193)2.60186989
85regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.57609135
86protein-cofactor linkage (GO:0018065)2.56410890
87establishment of protein localization to organelle (GO:0072594)2.56019370
88piRNA metabolic process (GO:0034587)2.48437201
89cellular biogenic amine catabolic process (GO:0042402)2.48269059
90amine catabolic process (GO:0009310)2.48269059
91GPI anchor metabolic process (GO:0006505)2.48075153
92protein localization to membrane (GO:0072657)2.46264649
93detection of light stimulus involved in visual perception (GO:0050908)2.45259612
94detection of light stimulus involved in sensory perception (GO:0050962)2.45259612
95transmission of nerve impulse (GO:0019226)2.44689499
96endoderm formation (GO:0001706)2.44123663
97positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.43433610
98mitochondrion morphogenesis (GO:0070584)2.43212995
99positive regulation of icosanoid secretion (GO:0032305)2.41878290
100innate immune response in mucosa (GO:0002227)2.39673185

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.83921610
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.55888765
3RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse3.19514600
4GABP_17652178_ChIP-ChIP_JURKAT_Human3.14807746
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.75977350
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.69946764
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.60621717
8HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.50226294
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.49095921
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.47220542
11KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.27726275
12ZNF274_21170338_ChIP-Seq_K562_Hela2.26943857
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.20869410
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.17664056
15IRF1_19129219_ChIP-ChIP_H3396_Human1.98281665
16VDR_22108803_ChIP-Seq_LS180_Human1.95174838
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.82140846
18BMI1_23680149_ChIP-Seq_NPCS_Mouse1.81350752
19GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.77243315
20VDR_23849224_ChIP-Seq_CD4+_Human1.67279360
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57333496
22NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.57153203
23ELK1_19687146_ChIP-ChIP_HELA_Human1.56112494
24TAF15_26573619_Chip-Seq_HEK293_Human1.54117718
25MYC_18555785_ChIP-Seq_MESCs_Mouse1.51836237
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.49894930
27CBX2_27304074_Chip-Seq_ESCs_Mouse1.48238298
28JARID2_20064375_ChIP-Seq_MESCs_Mouse1.45595101
29TP53_22573176_ChIP-Seq_HFKS_Human1.42330290
30EZH2_27304074_Chip-Seq_ESCs_Mouse1.42257787
31E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.38544353
32MYC_18940864_ChIP-ChIP_HL60_Human1.36807475
33GATA3_21878914_ChIP-Seq_MCF-7_Human1.34834127
34FOXP3_21729870_ChIP-Seq_TREG_Human1.34506957
35CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.33552879
36RNF2_27304074_Chip-Seq_NSC_Mouse1.33535254
37EZH2_27294783_Chip-Seq_ESCs_Mouse1.31401426
38FUS_26573619_Chip-Seq_HEK293_Human1.31366024
39ETV2_25802403_ChIP-Seq_MESCs_Mouse1.31114194
40TTF2_22483619_ChIP-Seq_HELA_Human1.29998032
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.28746536
42FOXA1_25329375_ChIP-Seq_VCAP_Human1.25471671
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.25471671
44NCOR_22424771_ChIP-Seq_293T_Human1.23595716
45MYC_19829295_ChIP-Seq_ESCs_Human1.23480632
46SUZ12_27294783_Chip-Seq_ESCs_Mouse1.23215324
47FOXH1_21741376_ChIP-Seq_EPCs_Human1.22758873
48CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.22042813
49TAF2_19829295_ChIP-Seq_ESCs_Human1.21771342
50EED_16625203_ChIP-ChIP_MESCs_Mouse1.21432360
51AUTS2_25519132_ChIP-Seq_293T-REX_Human1.21159243
52CTBP1_25329375_ChIP-Seq_LNCAP_Human1.20842908
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.20525038
54GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.20461275
55EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.19881320
56TDRD3_21172665_ChIP-Seq_MCF-7_Human1.19824510
57NANOG_20526341_ChIP-Seq_ESCs_Human1.19472103
58CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.19429989
59CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.18871140
60GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.18388125
61RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.17416835
62PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.16968087
63RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.16923727
64REST_21632747_ChIP-Seq_MESCs_Mouse1.16001312
65AR_20517297_ChIP-Seq_VCAP_Human1.15822098
66MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15284835
67GATA6_21074721_ChIP-Seq_CACO-2_Human1.15089834
68SRF_21415370_ChIP-Seq_HL-1_Mouse1.15069228
69PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.12988537
70E2F1_20622854_ChIP-Seq_HELA_Human1.10798062
71EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.10446251
72NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09682542
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08090759
74CREB1_15753290_ChIP-ChIP_HEK293T_Human1.07523203
75ERG_20517297_ChIP-Seq_VCAP_Human1.06076732
76EWS_26573619_Chip-Seq_HEK293_Human1.05088968
77IRF8_22096565_ChIP-ChIP_GC-B_Human1.05031535
78POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.04982569
79FOXH1_21741376_ChIP-Seq_ESCs_Human1.01385391
80MYC_18358816_ChIP-ChIP_MESCs_Mouse1.01035621
81YY1_22570637_ChIP-Seq_MALME-3M_Human1.00238630
82SA1_27219007_Chip-Seq_Bcells_Human1.00037511
83ER_23166858_ChIP-Seq_MCF-7_Human0.99808903
84BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.99569577
85JARID2_20075857_ChIP-Seq_MESCs_Mouse0.99261543
86ELK1_22589737_ChIP-Seq_MCF10A_Human0.99198388
87AR_21572438_ChIP-Seq_LNCaP_Human0.98968427
88RBPJ_21746931_ChIP-Seq_IB4_Human0.98742729
89BCL6_27268052_Chip-Seq_Bcells_Human0.98275232
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.97967651
91EGR1_23403033_ChIP-Seq_LIVER_Mouse0.97751652
92PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.97733536
93PCGF2_27294783_Chip-Seq_ESCs_Mouse0.97678488
94CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.97470418
95ERA_21632823_ChIP-Seq_H3396_Human0.96792582
96ETV1_20927104_ChIP-Seq_GIST48_Human0.95813613
97MYC_19079543_ChIP-ChIP_MESCs_Mouse0.94990307
98NOTCH1_21737748_ChIP-Seq_TLL_Human0.94401744
99TP53_20018659_ChIP-ChIP_R1E_Mouse0.93783039
100PHF8_20622853_ChIP-Seq_HELA_Human0.93468393

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.36487738
2MP0008877_abnormal_DNA_methylation3.87340952
3MP0006292_abnormal_olfactory_placode3.85732839
4MP0002638_abnormal_pupillary_reflex2.92289255
5MP0003787_abnormal_imprinting2.83283656
6MP0004142_abnormal_muscle_tone2.68519486
7MP0004145_abnormal_muscle_electrophysio2.32235332
8MP0003122_maternal_imprinting2.24395538
9MP0003646_muscle_fatigue2.16975591
10MP0005671_abnormal_response_to2.05175730
11MP0004147_increased_porphyrin_level2.04255333
12MP0008872_abnormal_physiological_respon1.91296111
13MP0003121_genomic_imprinting1.82149819
14MP0002102_abnormal_ear_morphology1.77543014
15MP0004885_abnormal_endolymph1.76919218
16MP0005377_hearing/vestibular/ear_phenot1.76513207
17MP0003878_abnormal_ear_physiology1.76513207
18MP0006072_abnormal_retinal_apoptosis1.76062007
19MP0002234_abnormal_pharynx_morphology1.73929877
20MP0002837_dystrophic_cardiac_calcinosis1.65270315
21MP0006276_abnormal_autonomic_nervous1.63536827
22MP0008789_abnormal_olfactory_epithelium1.59013709
23MP0001968_abnormal_touch/_nociception1.58733739
24MP0005551_abnormal_eye_electrophysiolog1.56888028
25MP0002160_abnormal_reproductive_system1.54485949
26MP0005646_abnormal_pituitary_gland1.53929299
27MP0002163_abnormal_gland_morphology1.49564245
28MP0001727_abnormal_embryo_implantation1.47118971
29MP0005645_abnormal_hypothalamus_physiol1.46221424
30MP0001835_abnormal_antigen_presentation1.41183607
31MP0001293_anophthalmia1.40151256
32MP0003879_abnormal_hair_cell1.39291107
33MP0005389_reproductive_system_phenotype1.37710876
34MP0002822_catalepsy1.37630215
35MP0001986_abnormal_taste_sensitivity1.37528049
36MP0002653_abnormal_ependyma_morphology1.37274948
37MP0000049_abnormal_middle_ear1.32945868
38MP0002736_abnormal_nociception_after1.32238714
39MP0003186_abnormal_redox_activity1.32224053
40MP0003011_delayed_dark_adaptation1.30295943
41MP0001905_abnormal_dopamine_level1.28510022
42MP0001440_abnormal_grooming_behavior1.28393537
43MP0009764_decreased_sensitivity_to1.28074946
44MP0002272_abnormal_nervous_system1.27913789
45MP0004043_abnormal_pH_regulation1.25811480
46MP0001970_abnormal_pain_threshold1.22879682
47MP0005253_abnormal_eye_physiology1.19578291
48MP0002733_abnormal_thermal_nociception1.19256795
49MP0006036_abnormal_mitochondrial_physio1.16684988
50MP0008875_abnormal_xenobiotic_pharmacok1.15129736
51MP0009745_abnormal_behavioral_response1.14753381
52MP0005379_endocrine/exocrine_gland_phen1.14016632
53MP0001529_abnormal_vocalization1.12990651
54MP0001919_abnormal_reproductive_system1.12570002
55MP0005195_abnormal_posterior_eye1.12563892
56MP0001485_abnormal_pinna_reflex1.12338350
57MP0000372_irregular_coat_pigmentation1.10236052
58MP0005394_taste/olfaction_phenotype1.07102992
59MP0005499_abnormal_olfactory_system1.07102992
60MP0001542_abnormal_bone_strength1.04653778
61MP0002184_abnormal_innervation1.02933149
62MP0008775_abnormal_heart_ventricle1.00987594
63MP0004133_heterotaxia1.00305967
64MP0002138_abnormal_hepatobiliary_system0.99841400
65MP0002752_abnormal_somatic_nervous0.96584334
66MP0003567_abnormal_fetal_cardiomyocyte0.95411240
67MP0008995_early_reproductive_senescence0.94911492
68MP0005423_abnormal_somatic_nervous0.94329468
69MP0002734_abnormal_mechanical_nocicepti0.93554617
70MP0009046_muscle_twitch0.93355527
71MP0002095_abnormal_skin_pigmentation0.89869726
72MP0005084_abnormal_gallbladder_morpholo0.87520087
73MP0006035_abnormal_mitochondrial_morpho0.86392850
74MP0000026_abnormal_inner_ear0.85882861
75MP0001963_abnormal_hearing_physiology0.85219192
76MP0000631_abnormal_neuroendocrine_gland0.84532778
77MP0002557_abnormal_social/conspecific_i0.82617061
78MP0000778_abnormal_nervous_system0.81952402
79MP0002572_abnormal_emotion/affect_behav0.80823178
80MP0002876_abnormal_thyroid_physiology0.80775115
81MP0001800_abnormal_humoral_immune0.76581702
82MP0005410_abnormal_fertilization0.74985952
83MP0005367_renal/urinary_system_phenotyp0.71224753
84MP0000516_abnormal_urinary_system0.71224753
85MP0000230_abnormal_systemic_arterial0.71074156
86MP0002210_abnormal_sex_determination0.70735709
87MP0000955_abnormal_spinal_cord0.70523244
88MP0003880_abnormal_central_pattern0.70501078
89MP0002928_abnormal_bile_duct0.70381058
90MP0005174_abnormal_tail_pigmentation0.69860387
91MP0004742_abnormal_vestibular_system0.69607945
92MP0004858_abnormal_nervous_system0.68818460
93MP0003638_abnormal_response/metabolism_0.66345661
94MP0003136_yellow_coat_color0.65548914
95MP0001486_abnormal_startle_reflex0.65311377
96MP0002277_abnormal_respiratory_mucosa0.62685417
97MP0002735_abnormal_chemical_nociception0.62361932
98MP0005636_abnormal_mineral_homeostasis0.61489140
99MP0003123_paternal_imprinting0.61440802
100MP0009785_altered_susceptibility_to0.61330245

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.15331858
2Reticulocytopenia (HP:0001896)4.68215300
3Mitochondrial inheritance (HP:0001427)4.30206896
4Acute necrotizing encephalopathy (HP:0006965)4.22819718
5Increased CSF lactate (HP:0002490)4.08787413
6Hepatocellular necrosis (HP:0001404)3.91306966
7Macrocytic anemia (HP:0001972)3.85923498
8Type II lissencephaly (HP:0007260)3.85282319
9Hepatic necrosis (HP:0002605)3.71368173
10Increased hepatocellular lipid droplets (HP:0006565)3.70217156
11Abnormal mitochondria in muscle tissue (HP:0008316)3.63013697
12Acute encephalopathy (HP:0006846)3.62718043
13Global brain atrophy (HP:0002283)3.61777736
14Lipid accumulation in hepatocytes (HP:0006561)3.50408660
15Elevated erythrocyte sedimentation rate (HP:0003565)3.48963860
16Congenital stationary night blindness (HP:0007642)3.44076637
17Progressive macrocephaly (HP:0004481)3.41126350
18Abnormal number of erythroid precursors (HP:0012131)3.39753251
19Stenosis of the external auditory canal (HP:0000402)3.25654075
20Renal Fanconi syndrome (HP:0001994)3.23011070
21Molar tooth sign on MRI (HP:0002419)3.18365291
22Abnormality of midbrain morphology (HP:0002418)3.18365291
23Pallor (HP:0000980)3.15691362
243-Methylglutaconic aciduria (HP:0003535)3.06019518
25Septo-optic dysplasia (HP:0100842)2.69008182
26Increased intramyocellular lipid droplets (HP:0012240)2.66508725
27Congenital, generalized hypertrichosis (HP:0004540)2.64487102
28Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.51722354
29Optic disc pallor (HP:0000543)2.50299643
30Exertional dyspnea (HP:0002875)2.48342995
31Methylmalonic acidemia (HP:0002912)2.47783626
32Retinal dysplasia (HP:0007973)2.45873354
33Cerebral edema (HP:0002181)2.43847519
34Agitation (HP:0000713)2.40442235
35Decreased electroretinogram (ERG) amplitude (HP:0000654)2.39810715
36CNS demyelination (HP:0007305)2.37656327
37Pancreatic cysts (HP:0001737)2.37246462
38Delayed CNS myelination (HP:0002188)2.36614413
39Decreased muscle mass (HP:0003199)2.32680420
40Respiratory failure (HP:0002878)2.31687580
41Increased serum lactate (HP:0002151)2.31461874
42Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.28965831
43Abnormality of alanine metabolism (HP:0010916)2.28965831
44Hyperalaninemia (HP:0003348)2.28965831
45Absent rod-and cone-mediated responses on ERG (HP:0007688)2.28558735
46Lactic acidosis (HP:0003128)2.28069338
47Abolished electroretinogram (ERG) (HP:0000550)2.27994454
48Abnormality of urine glucose concentration (HP:0011016)2.26878407
49Glycosuria (HP:0003076)2.26878407
50Abnormality of renal resorption (HP:0011038)2.24890857
51Medial flaring of the eyebrow (HP:0010747)2.24619774
52Increased muscle lipid content (HP:0009058)2.23502917
53Nephronophthisis (HP:0000090)2.22059462
54Decreased activity of mitochondrial respiratory chain (HP:0008972)2.20222838
55Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.20222838
56Pancreatic fibrosis (HP:0100732)2.18538773
57Sclerocornea (HP:0000647)2.18524314
58Cerebellar dysplasia (HP:0007033)2.15075555
59Leukodystrophy (HP:0002415)2.13047406
60Dynein arm defect of respiratory motile cilia (HP:0012255)2.13042269
61Absent/shortened dynein arms (HP:0200106)2.13042269
62Dyskinesia (HP:0100660)2.11485806
63Abnormal hemoglobin (HP:0011902)2.10666112
64Brushfield spots (HP:0001088)2.08507996
65True hermaphroditism (HP:0010459)2.06861601
66Abnormal ciliary motility (HP:0012262)2.04543548
67Methylmalonic aciduria (HP:0012120)2.03447055
68Morphological abnormality of the pyramidal tract (HP:0002062)2.03050414
69Hyperglycinemia (HP:0002154)2.03005808
70Aplasia/Hypoplasia of the sacrum (HP:0008517)1.97836833
71Absent thumb (HP:0009777)1.95885762
72Concave nail (HP:0001598)1.95401340
73Optic nerve hypoplasia (HP:0000609)1.94357350
74Hypoproteinemia (HP:0003075)1.92086130
75Neurodegeneration (HP:0002180)1.91977108
76Myokymia (HP:0002411)1.91313420
77Abnormal respiratory motile cilium physiology (HP:0012261)1.91228995
78Depressed nasal ridge (HP:0000457)1.91145137
79Renal cortical cysts (HP:0000803)1.89633290
80Hypobetalipoproteinemia (HP:0003563)1.88987885
81Hyperphosphaturia (HP:0003109)1.88246649
82Abnormal rod and cone electroretinograms (HP:0008323)1.87205385
83Decreased central vision (HP:0007663)1.86690667
84Patent foramen ovale (HP:0001655)1.85693430
85Type 2 muscle fiber atrophy (HP:0003554)1.85383955
86Abnormal drinking behavior (HP:0030082)1.84560727
87Polydipsia (HP:0001959)1.84560727
88Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.84086768
89Abnormality of the renal cortex (HP:0011035)1.83918892
90Pendular nystagmus (HP:0012043)1.83602143
91Abnormality of the renal medulla (HP:0100957)1.82851185
92Abnormality of magnesium homeostasis (HP:0004921)1.81719537
93Colon cancer (HP:0003003)1.80530627
94Male pseudohermaphroditism (HP:0000037)1.79233332
95Large eyes (HP:0001090)1.77043555
96Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.76358440
97Increased IgM level (HP:0003496)1.75300558
98Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.74653066
99Respiratory difficulties (HP:0002880)1.71437337
100Abnormal respiratory epithelium morphology (HP:0012253)1.71360282

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK193.84848560
2TIE13.32265400
3PINK12.92134324
4TLK12.82533524
5GRK12.75944725
6ADRBK22.68858392
7WNK42.59567420
8BCKDK2.45009507
9STK162.09214414
10ZAK1.98846314
11PIK3CA1.90165104
12PASK1.83443126
13MAP4K21.82443929
14DYRK21.78145193
15TAOK31.76239001
16NUAK11.73896248
17FRK1.55675440
18BMPR1B1.49076870
19PDK21.41792048
20MAP3K121.36683183
21WNK31.36046017
22VRK11.34902107
23KDR1.34547205
24VRK21.26906244
25NME21.26760010
26TRIM281.23348618
27MAP3K41.20224369
28OXSR11.14759894
29INSRR1.11422609
30TXK1.10717627
31MAP2K61.07266408
32TEC1.06699006
33PRKCG1.06360442
34CDK81.05659282
35PIM21.04462038
36DYRK1B1.02962827
37DAPK21.01456970
38MINK10.98762275
39SCYL20.98164793
40ABL20.95396669
41DAPK30.95136168
42MAPK150.93694419
43CAMKK20.93470767
44FES0.92147901
45PHKG20.92101816
46PHKG10.92101816
47ADRBK10.89456494
48PRKCQ0.87807127
49OBSCN0.86437524
50TGFBR10.84730194
51PKN10.84085552
52MYLK0.82064589
53CAMK10.79824239
54SYK0.78503534
55PLK40.76503555
56CSNK1G30.76295839
57PIM10.75967221
58ITK0.74171350
59PRKACA0.73792272
60MUSK0.72963009
61CSNK1G20.71246434
62KIT0.71187979
63NTRK20.70929955
64CAMKK10.69944656
65RPS6KA50.69676189
66LCK0.67303640
67MAPK130.65535974
68EPHB20.64350285
69RPS6KA60.64183003
70ROCK10.63714084
71WNK10.61526838
72CAMK2A0.61207993
73EPHA40.60559888
74ERN10.60500143
75CSNK2A20.60430301
76PRKCA0.59284936
77STK390.58984321
78PRKCD0.57407950
79MARK30.56830833
80ILK0.56497389
81TRPM70.54539137
82MAP3K110.54280040
83CSNK1G10.54061358
84LRRK20.53993241
85AKT20.53912572
86IKBKB0.53601615
87MAP2K70.53566874
88CSNK2A10.53534257
89BTK0.52890266
90PRKCI0.50677244
91PRKCH0.50152926
92AURKB0.49742666
93AURKA0.46549435
94GRK60.45784085
95PTK2B0.45012745
96GRK50.44853534
97RPS6KL10.44839107
98RPS6KC10.44839107
99STK110.43125368
100IRAK40.42571087

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.16218832
2Oxidative phosphorylation_Homo sapiens_hsa001904.44420419
3Parkinsons disease_Homo sapiens_hsa050123.71683840
4Asthma_Homo sapiens_hsa053103.42589414
5Alzheimers disease_Homo sapiens_hsa050102.74249175
6Cardiac muscle contraction_Homo sapiens_hsa042602.68324082
7Autoimmune thyroid disease_Homo sapiens_hsa053202.57469176
8Allograft rejection_Homo sapiens_hsa053302.54109842
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.49216805
10Huntingtons disease_Homo sapiens_hsa050162.43469451
11Graft-versus-host disease_Homo sapiens_hsa053322.38242178
12Intestinal immune network for IgA production_Homo sapiens_hsa046722.34382699
13Proteasome_Homo sapiens_hsa030502.07843618
14Type I diabetes mellitus_Homo sapiens_hsa049402.06354461
15Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.00560369
16RNA polymerase_Homo sapiens_hsa030201.90719158
17Protein export_Homo sapiens_hsa030601.79642884
18Homologous recombination_Homo sapiens_hsa034401.79407026
19Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.78211177
20Nitrogen metabolism_Homo sapiens_hsa009101.71779573
21Linoleic acid metabolism_Homo sapiens_hsa005911.71370300
22RNA degradation_Homo sapiens_hsa030181.48806826
23Phototransduction_Homo sapiens_hsa047441.47658275
24alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.41672210
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.35754106
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.23998647
27Viral myocarditis_Homo sapiens_hsa054161.13793880
28Rheumatoid arthritis_Homo sapiens_hsa053231.08847970
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95718651
30Staphylococcus aureus infection_Homo sapiens_hsa051500.92920325
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.92113981
32Antigen processing and presentation_Homo sapiens_hsa046120.90738784
33Peroxisome_Homo sapiens_hsa041460.88930348
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87562985
35Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.87366507
36Primary immunodeficiency_Homo sapiens_hsa053400.87114927
37Systemic lupus erythematosus_Homo sapiens_hsa053220.86725161
38Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.85983229
39Caffeine metabolism_Homo sapiens_hsa002320.84813485
40Tryptophan metabolism_Homo sapiens_hsa003800.82808706
41Arachidonic acid metabolism_Homo sapiens_hsa005900.82175717
42Ether lipid metabolism_Homo sapiens_hsa005650.80415358
43Fat digestion and absorption_Homo sapiens_hsa049750.76600503
44Chemical carcinogenesis_Homo sapiens_hsa052040.75486487
45Regulation of autophagy_Homo sapiens_hsa041400.75184180
46Olfactory transduction_Homo sapiens_hsa047400.74583108
47Pyrimidine metabolism_Homo sapiens_hsa002400.73519030
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.70739792
49Maturity onset diabetes of the young_Homo sapiens_hsa049500.69938283
50Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.69217562
51Propanoate metabolism_Homo sapiens_hsa006400.68838198
52Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.67286645
53Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.66421279
54One carbon pool by folate_Homo sapiens_hsa006700.65968512
55Retinol metabolism_Homo sapiens_hsa008300.65868169
56Pentose and glucuronate interconversions_Homo sapiens_hsa000400.64622773
57Basal transcription factors_Homo sapiens_hsa030220.63967473
58Nucleotide excision repair_Homo sapiens_hsa034200.63760463
59Butanoate metabolism_Homo sapiens_hsa006500.63358179
60Base excision repair_Homo sapiens_hsa034100.61636800
61Hematopoietic cell lineage_Homo sapiens_hsa046400.61186226
62Metabolic pathways_Homo sapiens_hsa011000.60788644
63Nicotine addiction_Homo sapiens_hsa050330.57380716
64Steroid hormone biosynthesis_Homo sapiens_hsa001400.55904728
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.50156765
66Purine metabolism_Homo sapiens_hsa002300.50009704
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.48525922
68Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.48291289
69Taste transduction_Homo sapiens_hsa047420.47291639
70Fanconi anemia pathway_Homo sapiens_hsa034600.45837184
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.45625801
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44757610
73Morphine addiction_Homo sapiens_hsa050320.42915174
74Drug metabolism - other enzymes_Homo sapiens_hsa009830.42379477
75Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.40519096
76Collecting duct acid secretion_Homo sapiens_hsa049660.38005554
77RNA transport_Homo sapiens_hsa030130.35087889
78Sulfur metabolism_Homo sapiens_hsa009200.34875899
79Spliceosome_Homo sapiens_hsa030400.33310496
80Leishmaniasis_Homo sapiens_hsa051400.32969954
81Mismatch repair_Homo sapiens_hsa034300.31299602
82Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.28877038
83Tyrosine metabolism_Homo sapiens_hsa003500.27464946
84Salivary secretion_Homo sapiens_hsa049700.26044659
85Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.25451413
86GABAergic synapse_Homo sapiens_hsa047270.24203589
87Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.23716560
88Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.19817044
89Insulin secretion_Homo sapiens_hsa049110.19293828
90Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.17254972
91Serotonergic synapse_Homo sapiens_hsa047260.16525628
92Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.16042362
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.15597521
94Ovarian steroidogenesis_Homo sapiens_hsa049130.15561735
95NOD-like receptor signaling pathway_Homo sapiens_hsa046210.15301330
96Starch and sucrose metabolism_Homo sapiens_hsa005000.13563040
97Fatty acid degradation_Homo sapiens_hsa000710.13490791
98Circadian entrainment_Homo sapiens_hsa047130.12899360
99Phagosome_Homo sapiens_hsa041450.11410600
100Steroid biosynthesis_Homo sapiens_hsa001000.10951103

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »