RPL27

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* viral transcription (GO:0019083)7.44403394
2* translational termination (GO:0006415)7.18405056
3ribosomal small subunit biogenesis (GO:0042274)6.98489847
4ribosomal small subunit assembly (GO:0000028)6.74520491
5maturation of SSU-rRNA (GO:0030490)6.33359441
6* translational elongation (GO:0006414)6.26118480
7* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.19552504
8* cotranslational protein targeting to membrane (GO:0006613)6.09297809
9* protein targeting to ER (GO:0045047)6.06751077
10* establishment of protein localization to endoplasmic reticulum (GO:0072599)5.77644672
11* protein localization to endoplasmic reticulum (GO:0070972)5.70056912
12* translational initiation (GO:0006413)5.69832463
13* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.67831267
14ribosomal large subunit biogenesis (GO:0042273)5.67151733
15* cellular protein complex disassembly (GO:0043624)5.64410510
16* viral life cycle (GO:0019058)5.63098581
17DNA deamination (GO:0045006)5.14827305
18* protein complex disassembly (GO:0043241)4.95195499
19ribonucleoprotein complex biogenesis (GO:0022613)4.76293418
20* macromolecular complex disassembly (GO:0032984)4.68513108
21* translation (GO:0006412)4.63653386
22oxidative phosphorylation (GO:0006119)4.50141585
23formation of translation preinitiation complex (GO:0001731)4.46606631
24* nuclear-transcribed mRNA catabolic process (GO:0000956)4.26714336
25proteasome assembly (GO:0043248)4.25632496
26DNA strand elongation involved in DNA replication (GO:0006271)4.13575610
27rRNA processing (GO:0006364)4.08797037
28establishment of integrated proviral latency (GO:0075713)4.08302445
29spliceosomal snRNP assembly (GO:0000387)4.07244304
30* mRNA catabolic process (GO:0006402)4.03806901
31telomere maintenance via semi-conservative replication (GO:0032201)4.02843619
32mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.97127242
33* protein targeting to membrane (GO:0006612)3.96140884
34rRNA metabolic process (GO:0016072)3.93046027
35DNA strand elongation (GO:0022616)3.91269564
36termination of RNA polymerase III transcription (GO:0006386)3.90414437
37transcription elongation from RNA polymerase III promoter (GO:0006385)3.90414437
38energy coupled proton transport, down electrochemical gradient (GO:0015985)3.84241607
39ATP synthesis coupled proton transport (GO:0015986)3.84241607
40* RNA catabolic process (GO:0006401)3.82822458
41cellular component biogenesis (GO:0044085)3.82255663
42negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.77621097
43spliceosomal complex assembly (GO:0000245)3.77599155
44chaperone-mediated protein transport (GO:0072321)3.74528585
45DNA replication initiation (GO:0006270)3.72422478
46pseudouridine synthesis (GO:0001522)3.64113279
47ribosome biogenesis (GO:0042254)3.63914090
48regulation of translational fidelity (GO:0006450)3.57881442
49nucleobase-containing small molecule interconversion (GO:0015949)3.56512142
50positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.52366180
51telomere maintenance via recombination (GO:0000722)3.50690950
52anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.49107075
53negative regulation of ligase activity (GO:0051352)3.47993587
54negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.47993587
55regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.47818641
56establishment of protein localization to mitochondrial membrane (GO:0090151)3.47672824
57ribosome assembly (GO:0042255)3.45978044
58DNA replication checkpoint (GO:0000076)3.41658734
59DNA unwinding involved in DNA replication (GO:0006268)3.41207863
60deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.40497360
61rRNA modification (GO:0000154)3.40228853
62exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.39931321
63nucleobase biosynthetic process (GO:0046112)3.36354639
64* establishment of protein localization to membrane (GO:0090150)3.35397273
65transcription-coupled nucleotide-excision repair (GO:0006283)3.35341975
66protein targeting to mitochondrion (GO:0006626)3.34822012
67establishment of viral latency (GO:0019043)3.33471158
68DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.31979093
69nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.31349941
70respiratory electron transport chain (GO:0022904)3.29920232
717-methylguanosine mRNA capping (GO:0006370)3.28097962
72signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.26652153
73intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.26652153
74signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25447568
75signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25447568
76signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25447568
77mitotic recombination (GO:0006312)3.24272214
78pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.23728193
79RNA capping (GO:0036260)3.21227045
807-methylguanosine RNA capping (GO:0009452)3.21227045
81signal transduction involved in DNA damage checkpoint (GO:0072422)3.20869678
82signal transduction involved in DNA integrity checkpoint (GO:0072401)3.20869678
83rRNA transcription (GO:0009303)3.19350729
84telomere maintenance via telomere lengthening (GO:0010833)3.18864907
85electron transport chain (GO:0022900)3.17997216
86signal transduction involved in cell cycle checkpoint (GO:0072395)3.16586193
87* protein targeting (GO:0006605)3.15500058
88UTP biosynthetic process (GO:0006228)3.13286181
89termination of RNA polymerase I transcription (GO:0006363)3.12763751
90nucleotide-excision repair, DNA gap filling (GO:0006297)3.12351718
91transcription elongation from RNA polymerase I promoter (GO:0006362)3.11890173
92regulation of cellular amino acid metabolic process (GO:0006521)3.11657600
93CENP-A containing nucleosome assembly (GO:0034080)3.11477011
94peptidyl-arginine omega-N-methylation (GO:0035247)3.11128708
95viral mRNA export from host cell nucleus (GO:0046784)3.10605552
96purine nucleobase biosynthetic process (GO:0009113)3.09683154
97GTP biosynthetic process (GO:0006183)3.09169950
98antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.07942418
99chromatin remodeling at centromere (GO:0031055)3.07689749
100positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.06823472
101transcription from RNA polymerase I promoter (GO:0006360)3.06311190
102mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.05946425
103establishment of protein localization to mitochondrion (GO:0072655)3.05507030
104mitotic metaphase plate congression (GO:0007080)3.04956674
105ncRNA processing (GO:0034470)3.00881617
106mitotic chromosome condensation (GO:0007076)2.99058795
107peptidyl-histidine modification (GO:0018202)2.98842787
108regulation of mitochondrial translation (GO:0070129)2.98023366
109* establishment of protein localization to organelle (GO:0072594)2.96856816
110pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.94902780
111folic acid-containing compound biosynthetic process (GO:0009396)2.94588446
112kinetochore assembly (GO:0051382)2.94347431
113positive regulation of ligase activity (GO:0051351)2.93551860
114DNA replication-dependent nucleosome organization (GO:0034723)2.92930793
115DNA replication-dependent nucleosome assembly (GO:0006335)2.92930793
116histone arginine methylation (GO:0034969)2.92928585
117heterochromatin organization (GO:0070828)2.90668134
118DNA-templated transcription, termination (GO:0006353)2.90305757
119ncRNA metabolic process (GO:0034660)2.89878554
120guanosine-containing compound biosynthetic process (GO:1901070)2.89099036
121G1/S transition of mitotic cell cycle (GO:0000082)2.87991239
122protein maturation by protein folding (GO:0022417)2.87692655
123protein localization to mitochondrion (GO:0070585)2.86256019
124pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.85273623
125muscle cell fate commitment (GO:0042693)2.85110354
126negative regulation of RNA splicing (GO:0033119)2.84150181
127pentose metabolic process (GO:0019321)2.83610789
128kinetochore organization (GO:0051383)2.82920126
129pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.82525964
130L-serine metabolic process (GO:0006563)2.81554534
131ribonucleoside triphosphate biosynthetic process (GO:0009201)2.81246894
132ATP biosynthetic process (GO:0006754)2.80641019
133pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.79694937
134proline biosynthetic process (GO:0006561)2.78797537
135purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.76091802
136purine nucleoside triphosphate biosynthetic process (GO:0009145)2.74853120
137pyrimidine nucleotide catabolic process (GO:0006244)2.73588875
138regulation of mammary gland epithelial cell proliferation (GO:0033599)2.68026382
139purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.66354621
140purine nucleoside monophosphate biosynthetic process (GO:0009127)2.66354621
141* protein localization to membrane (GO:0072657)2.64688155

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.99537576
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.84916148
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.12131071
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.81942771
5* EST1_17652178_ChIP-ChIP_JURKAT_Human3.69190205
6* GABP_17652178_ChIP-ChIP_JURKAT_Human3.65871146
7* ETS1_20019798_ChIP-Seq_JURKAT_Human3.47449811
8* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.44893167
9SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.40038920
10* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.36263346
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse3.21031634
12CREB1_15753290_ChIP-ChIP_HEK293T_Human3.11084786
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse3.05501419
14E2F4_17652178_ChIP-ChIP_JURKAT_Human2.98318445
15* HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.87567564
16* XRN2_22483619_ChIP-Seq_HELA_Human2.75828543
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.75130080
18NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.73896282
19FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.67613223
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.58889388
21* VDR_23849224_ChIP-Seq_CD4+_Human2.50215641
22ELF1_17652178_ChIP-ChIP_JURKAT_Human2.39309513
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.38555465
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.34588644
25DCP1A_22483619_ChIP-Seq_HELA_Human2.34310174
26TTF2_22483619_ChIP-Seq_HELA_Human2.25302008
27* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.23902914
28CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.21281897
29FOXP3_21729870_ChIP-Seq_TREG_Human2.15168270
30E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.13297851
31THAP11_20581084_ChIP-Seq_MESCs_Mouse2.05789666
32* GABP_19822575_ChIP-Seq_HepG2_Human1.96450224
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.94540270
34ELK1_19687146_ChIP-ChIP_HELA_Human1.93357703
35MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.87329601
36* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.82146125
37POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.80995624
38ZNF263_19887448_ChIP-Seq_K562_Human1.80181349
39* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.75825567
40ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.75068444
41* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.71904993
42MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69759527
43MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.67646607
44SRF_21415370_ChIP-Seq_HL-1_Mouse1.65120870
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58133031
46CIITA_25753668_ChIP-Seq_RAJI_Human1.56274761
47PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.55356335
48YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49602790
49* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46501909
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.45536929
51E2F1_21310950_ChIP-Seq_MCF-7_Human1.44300750
52* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.43539078
53POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.43484094
54* PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.42871886
55* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.41797281
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.41049619
57* ELK1_22589737_ChIP-Seq_MCF10A_Human1.40810506
58AR_21909140_ChIP-Seq_LNCAP_Human1.38346380
59TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.37514242
60CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.35299503
61* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.33460052
62KDM5A_27292631_Chip-Seq_BREAST_Human1.32967863
63TET1_21451524_ChIP-Seq_MESCs_Mouse1.29695319
64ERG_20887958_ChIP-Seq_HPC-7_Mouse1.29480245
65CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.24576592
66* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24124641
67MYC_18940864_ChIP-ChIP_HL60_Human1.20721369
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.19890851
69STAT3_1855785_ChIP-Seq_MESCs_Mouse1.19540461
70* POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.18710980
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.16420365
72CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.15644892
73CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.13257065
74BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.12614821
75MYC_22102868_ChIP-Seq_BL_Human1.11375961
76ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.10735484
77* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.09849998
78SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.09815385
79CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.09656543
80SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.09484791
81LXR_22292898_ChIP-Seq_THP-1_Human1.09016253
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.09011084
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.08364397
84SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.07491206
85* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07216369
86ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.05274658
87SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.04337659
88SRY_22984422_ChIP-ChIP_TESTIS_Rat1.03818486
89ELK3_25401928_ChIP-Seq_HUVEC_Human1.02780024
90TP63_19390658_ChIP-ChIP_HaCaT_Human1.02774648
91KLF4_18555785_ChIP-Seq_MESCs_Mouse1.02182751
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.02026676
93* FOXP1_21924763_ChIP-Seq_HESCs_Human0.99646140
94TFEB_21752829_ChIP-Seq_HELA_Human0.98336820
95* OCT4_18692474_ChIP-Seq_MEFs_Mouse0.98230260
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98080646
97DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96153731
98E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95378281
99RACK7_27058665_Chip-Seq_MCF-7_Human0.94625236
100HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94596443
101ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.94128272
102* CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.93894606
103TCF3_18692474_ChIP-Seq_MEFs_Mouse0.93661119
104NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92018225
105* MAF_26560356_Chip-Seq_TH2_Human0.91900544
106TP63_17297297_ChIP-ChIP_HaCaT_Human0.91655777
107TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.90849017
108ESR1_15608294_ChIP-ChIP_MCF-7_Human0.90469874
109VDR_21846776_ChIP-Seq_THP-1_Human0.90315264
110* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.89779567
111* SPI1_23547873_ChIP-Seq_NB4_Human0.89537398
112* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.88379144
113* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87165456
114RBPJ_22232070_ChIP-Seq_NCS_Mouse0.87132615
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.86973144
116KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.86973144
117KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.86973144
118* CTCF_18555785_ChIP-Seq_MESCs_Mouse0.85047975
119KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.82405907
120ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.81591432

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.59244659
2MP0004957_abnormal_blastocyst_morpholog4.60632664
3MP0009379_abnormal_foot_pigmentation4.25481861
4MP0003111_abnormal_nucleus_morphology3.88330098
5MP0003077_abnormal_cell_cycle3.78446934
6MP0010094_abnormal_chromosome_stability3.74815441
7MP0008057_abnormal_DNA_replication3.39242945
8MP0008932_abnormal_embryonic_tissue3.01919608
9MP0008058_abnormal_DNA_repair3.00554679
10MP0008007_abnormal_cellular_replicative2.64992295
11MP0000678_abnormal_parathyroid_gland2.48556525
12MP0003123_paternal_imprinting2.19801682
13MP0003786_premature_aging2.15914872
14MP0001730_embryonic_growth_arrest2.02034382
15MP0002796_impaired_skin_barrier1.94511967
16MP0000350_abnormal_cell_proliferation1.94265615
17MP0010030_abnormal_orbit_morphology1.90640724
18MP0002234_abnormal_pharynx_morphology1.88757265
19MP0003718_maternal_effect1.84163337
20MP0009333_abnormal_splenocyte_physiolog1.82169493
21MP0002396_abnormal_hematopoietic_system1.78392667
22MP0004185_abnormal_adipocyte_glucose1.75860901
23MP0005451_abnormal_body_composition1.75778007
24MP0002877_abnormal_melanocyte_morpholog1.75137916
25MP0000490_abnormal_crypts_of1.71859666
26MP0002132_abnormal_respiratory_system1.67683912
27MP0004133_heterotaxia1.64709503
28MP0006292_abnormal_olfactory_placode1.55526242
29MP0002249_abnormal_larynx_morphology1.55192845
30MP0003806_abnormal_nucleotide_metabolis1.52828779
31MP0001873_stomach_inflammation1.51025900
32MP0003186_abnormal_redox_activity1.50672277
33MP0001697_abnormal_embryo_size1.50069473
34MP0003763_abnormal_thymus_physiology1.45290652
35MP0000313_abnormal_cell_death1.44006651
36MP0003315_abnormal_perineum_morphology1.42973355
37MP0002080_prenatal_lethality1.39761841
38MP0001672_abnormal_embryogenesis/_devel1.35034481
39MP0005380_embryogenesis_phenotype1.35034481
40MP0002019_abnormal_tumor_incidence1.31819665
41MP0001661_extended_life_span1.30455818
42MP0002085_abnormal_embryonic_tissue1.29766665
43MP0008877_abnormal_DNA_methylation1.26588152
44MP0000733_abnormal_muscle_development1.25214990
45MP0003136_yellow_coat_color1.24462585
46MP0000858_altered_metastatic_potential1.24369484
47MP0000703_abnormal_thymus_morphology1.23660083
48MP0005408_hypopigmentation1.23036194
49MP0010352_gastrointestinal_tract_polyps1.21368579
50MP0003567_abnormal_fetal_cardiomyocyte1.19073375
51MP0003705_abnormal_hypodermis_morpholog1.17816174
52MP0003984_embryonic_growth_retardation1.15669549
53MP0006035_abnormal_mitochondrial_morpho1.15623513
54MP0008260_abnormal_autophagy1.13905698
55MP0002088_abnormal_embryonic_growth/wei1.13106116
56MP0003941_abnormal_skin_development1.11763667
57MP0002722_abnormal_immune_system1.10294722
58MP0000358_abnormal_cell_content/1.10205564
59MP0001853_heart_inflammation1.10065516
60MP0004233_abnormal_muscle_weight1.08280671
61MP0003890_abnormal_embryonic-extraembry1.07753650
62MP0006036_abnormal_mitochondrial_physio1.06921629
63MP0001529_abnormal_vocalization1.06089402
64MP0002938_white_spotting1.06070145
65MP0002398_abnormal_bone_marrow1.05517395
66MP0004808_abnormal_hematopoietic_stem1.05385638
67MP0000750_abnormal_muscle_regeneration1.04086370
68MP0002084_abnormal_developmental_patter1.03690954
69MP0001293_anophthalmia1.01999707
70MP0000762_abnormal_tongue_morphology1.00864882
71MP0009672_abnormal_birth_weight1.00683482
72MP0002277_abnormal_respiratory_mucosa1.00382389
73MP0001881_abnormal_mammary_gland1.00261278
74MP0000689_abnormal_spleen_morphology0.99368061
75MP0008789_abnormal_olfactory_epithelium0.98501310
76MP0002160_abnormal_reproductive_system0.96449317
77MP0001346_abnormal_lacrimal_gland0.96437765
78MP0000049_abnormal_middle_ear0.93787794
79MP0002163_abnormal_gland_morphology0.92863031
80MP0002102_abnormal_ear_morphology0.92767256
81MP0005075_abnormal_melanosome_morpholog0.92714263
82MP0003119_abnormal_digestive_system0.92526658
83MP0002086_abnormal_extraembryonic_tissu0.92189412
84MP0004858_abnormal_nervous_system0.92174378
85MP0005174_abnormal_tail_pigmentation0.92028417
86MP0002751_abnormal_autonomic_nervous0.90481031
87MP0004381_abnormal_hair_follicle0.88656948
88MP0004197_abnormal_fetal_growth/weight/0.88631274
89MP0002210_abnormal_sex_determination0.88539645
90MP0002429_abnormal_blood_cell0.87867409
91MP0005389_reproductive_system_phenotype0.85263678
92MP0005058_abnormal_lysosome_morphology0.84989112
93MP0008995_early_reproductive_senescence0.84198091
94MP0002111_abnormal_tail_morphology0.83099955
95MP0002697_abnormal_eye_size0.82642613
96MP0009697_abnormal_copulation0.82607237
97MP0005666_abnormal_adipose_tissue0.82180769
98MP0000372_irregular_coat_pigmentation0.81741949
99MP0000681_abnormal_thyroid_gland0.80901020
100MP0003453_abnormal_keratinocyte_physiol0.80407703
101MP0001727_abnormal_embryo_implantation0.79726845
102MP0001145_abnormal_male_reproductive0.79674586
103MP0000716_abnormal_immune_system0.76882666
104MP0001764_abnormal_homeostasis0.75675059
105MP0003121_genomic_imprinting0.74983759
106MP0001286_abnormal_eye_development0.74351463
107MP0001849_ear_inflammation0.73838803
108MP0005397_hematopoietic_system_phenotyp0.73311808
109MP0001545_abnormal_hematopoietic_system0.73311808
110MP0000537_abnormal_urethra_morphology0.70860012
111MP0002095_abnormal_skin_pigmentation0.69389830
112MP0006054_spinal_hemorrhage0.69342047
113MP0005379_endocrine/exocrine_gland_phen0.68712983
114MP0005501_abnormal_skin_physiology0.68644284
115MP0001919_abnormal_reproductive_system0.68499264
116MP0005330_cardiomyopathy0.68183969
117MP0002405_respiratory_system_inflammati0.68163261
118MP0003938_abnormal_ear_development0.66572145
119MP0010234_abnormal_vibrissa_follicle0.65503267
120MP0001348_abnormal_lacrimal_gland0.64761025
121MP0001800_abnormal_humoral_immune0.64508151
122MP0004264_abnormal_extraembryonic_tissu0.63952209
123MP0010307_abnormal_tumor_latency0.63873113
124MP0005671_abnormal_response_to0.63802460
125MP0002420_abnormal_adaptive_immunity0.63037662
126MP0000653_abnormal_sex_gland0.62927776
127MP0005384_cellular_phenotype0.62253453
128MP0001216_abnormal_epidermal_layer0.61861714
129MP0002638_abnormal_pupillary_reflex0.61853798
130MP0001819_abnormal_immune_cell0.61458672
131MP0000627_abnormal_mammary_gland0.59178785
132MP0009053_abnormal_anal_canal0.58082767
133MP0002452_abnormal_antigen_presenting0.55341215
134MP0002723_abnormal_immune_serum0.54533786
135MP0001929_abnormal_gametogenesis0.52629343
136MP0005023_abnormal_wound_healing0.51611262

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)7.37972668
2Reticulocytopenia (HP:0001896)6.71379234
3Abnormal number of erythroid precursors (HP:0012131)6.70075280
4Macrocytic anemia (HP:0001972)5.30451464
5Pallor (HP:0000980)4.82833512
6Acute necrotizing encephalopathy (HP:0006965)3.91101506
7Birth length less than 3rd percentile (HP:0003561)3.89570346
8Breast hypoplasia (HP:0003187)3.71667285
9Mitochondrial inheritance (HP:0001427)3.71347008
10Oral leukoplakia (HP:0002745)3.53673631
11Abnormal mitochondria in muscle tissue (HP:0008316)3.48716297
12Decreased activity of mitochondrial respiratory chain (HP:0008972)3.42898856
13Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.42898856
14Aplasia/Hypoplasia of the sacrum (HP:0008517)3.41400317
15Hepatocellular necrosis (HP:0001404)3.40451873
16Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.28339036
17Increased hepatocellular lipid droplets (HP:0006565)3.28327725
18Double outlet right ventricle (HP:0001719)3.27200890
19Congenital malformation of the right heart (HP:0011723)3.27200890
20Increased CSF lactate (HP:0002490)3.25944093
21Trismus (HP:0000211)3.22548512
22Aplastic anemia (HP:0001915)3.14751087
23Rough bone trabeculation (HP:0100670)3.13014412
24Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.07631234
25Truncus arteriosus (HP:0001660)3.07544712
26Absent thumb (HP:0009777)3.00523880
27Colon cancer (HP:0003003)3.00261655
28Progressive macrocephaly (HP:0004481)3.00070564
29Multiple enchondromatosis (HP:0005701)2.99949781
30Acute encephalopathy (HP:0006846)2.96557113
31Cerebral hypomyelination (HP:0006808)2.95768957
32Carpal bone hypoplasia (HP:0001498)2.92849697
33Increased serum lactate (HP:0002151)2.87699858
34Hepatic necrosis (HP:0002605)2.80983130
353-Methylglutaconic aciduria (HP:0003535)2.80371096
36Lipid accumulation in hepatocytes (HP:0006561)2.79725783
37Exertional dyspnea (HP:0002875)2.75361805
38Abnormal hemoglobin (HP:0011902)2.71898423
39Patellar aplasia (HP:0006443)2.71030994
40Selective tooth agenesis (HP:0001592)2.67677409
41Seborrheic dermatitis (HP:0001051)2.61391733
42Hypoplastic left heart (HP:0004383)2.60756082
43Aplasia/Hypoplasia of the patella (HP:0006498)2.59185006
4411 pairs of ribs (HP:0000878)2.51578474
45Exercise intolerance (HP:0003546)2.50446279
46Microretrognathia (HP:0000308)2.49495366
47Hypertensive crisis (HP:0100735)2.48614328
48Cleft eyelid (HP:0000625)2.46764272
49Premature graying of hair (HP:0002216)2.46051120
50Redundant skin (HP:0001582)2.45912638
51Ragged-red muscle fibers (HP:0003200)2.43696772
52Triphalangeal thumb (HP:0001199)2.43229068
53Renal Fanconi syndrome (HP:0001994)2.41967766
54Absent radius (HP:0003974)2.41477726
55Hyperthyroidism (HP:0000836)2.39674205
56Horseshoe kidney (HP:0000085)2.35746395
57Abnormal number of incisors (HP:0011064)2.34362124
58Abnormal ventriculo-arterial connection (HP:0011563)2.32354622
59Transposition of the great arteries (HP:0001669)2.32354622
60Abnormal connection of the cardiac segments (HP:0011545)2.32354622
61Respiratory failure (HP:0002878)2.30374552
62Abnormal trabecular bone morphology (HP:0100671)2.29365627
63Abnormality of the anterior horn cell (HP:0006802)2.29004830
64Degeneration of anterior horn cells (HP:0002398)2.29004830
65Abnormality of reticulocytes (HP:0004312)2.25621532
66Increased intramyocellular lipid droplets (HP:0012240)2.25095614
67Respiratory difficulties (HP:0002880)2.24927482
68Glossoptosis (HP:0000162)2.24857931
69Depressed nasal ridge (HP:0000457)2.24629719
70Absent forearm bone (HP:0003953)2.24246041
71Aplasia involving forearm bones (HP:0009822)2.24246041
72Hypoplastic heart (HP:0001961)2.21284155
73Stenosis of the external auditory canal (HP:0000402)2.18808480
74Abnormality of the preputium (HP:0100587)2.18599182
75Meckel diverticulum (HP:0002245)2.15840716
76Secondary amenorrhea (HP:0000869)2.15705831
77Cellular immunodeficiency (HP:0005374)2.14830582
78Hypoplasia of the radius (HP:0002984)2.12784934
79Lactic acidosis (HP:0003128)2.11679491
80Increased serum pyruvate (HP:0003542)2.10762093
81Abnormality of glycolysis (HP:0004366)2.10762093
82Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.10721136
83Sparse eyelashes (HP:0000653)2.10368769
84Premature ovarian failure (HP:0008209)2.10127050
85Abnormality of the ileum (HP:0001549)2.08406519
86Neoplasm of the pancreas (HP:0002894)2.07877442
87Type I transferrin isoform profile (HP:0003642)2.07576338
88Microvesicular hepatic steatosis (HP:0001414)2.05880188
89Pancytopenia (HP:0001876)2.03314114
90Chromsome breakage (HP:0040012)2.00379760
91Supernumerary spleens (HP:0009799)1.99897558
92Atresia of the external auditory canal (HP:0000413)1.98017569
93Abnormality of the tricuspid valve (HP:0001702)1.97494075
94Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.96883349
95Asplenia (HP:0001746)1.96680396
96Congenital, generalized hypertrichosis (HP:0004540)1.96475718
97Abnormality of T cell physiology (HP:0011840)1.95227100
98Progressive muscle weakness (HP:0003323)1.93404410
99Aplasia/Hypoplasia of the thymus (HP:0010515)1.92356616
100Periauricular skin pits (HP:0100277)1.91996386
101Preauricular pit (HP:0004467)1.91996386
102Unilateral renal agenesis (HP:0000122)1.91674842
103Squamous cell carcinoma (HP:0002860)1.91417230
104Hypoparathyroidism (HP:0000829)1.90378062
105Abnormality of abdominal situs (HP:0011620)1.89766208
106Abdominal situs inversus (HP:0003363)1.89766208
107Chromosomal breakage induced by crosslinking agents (HP:0003221)1.88146936
108Cerebral edema (HP:0002181)1.86498888
109Leukodystrophy (HP:0002415)1.85134173
110Emotional lability (HP:0000712)1.84719318
111Progressive external ophthalmoplegia (HP:0000590)1.84047155
112Tracheoesophageal fistula (HP:0002575)1.83909054
113Duplicated collecting system (HP:0000081)1.82319811
114Abnormal lung lobation (HP:0002101)1.82104162
115Viral hepatitis (HP:0006562)1.81220608
116Thrombocytosis (HP:0001894)1.80939459
117Bone marrow hypocellularity (HP:0005528)1.80413795
118Myelodysplasia (HP:0002863)1.79844562
119Aplasia/Hypoplasia of the spleen (HP:0010451)1.79482117
120Gout (HP:0001997)1.78878389
121Amniotic constriction ring (HP:0009775)1.78654482
122Abnormality of placental membranes (HP:0011409)1.78654482
123Abnormality of small intestinal villus morphology (HP:0011472)1.77960779
124Villous atrophy (HP:0011473)1.77960779
125IgM deficiency (HP:0002850)1.77399748
126Thick lower lip vermilion (HP:0000179)1.77356484
127Facial cleft (HP:0002006)1.76747531
128Increased muscle lipid content (HP:0009058)1.74930581
129Premature skin wrinkling (HP:0100678)1.74030268
130Abnormality of methionine metabolism (HP:0010901)1.73712484
131Congenital ichthyosiform erythroderma (HP:0007431)1.73451168
132Muscle fiber atrophy (HP:0100295)1.71966140
133Abnormality of the umbilical cord (HP:0010881)1.71225968
134Broad distal phalanx of finger (HP:0009836)1.65243125
135Short middle phalanx of the 5th finger (HP:0004220)1.64455256
136Testicular atrophy (HP:0000029)1.64297473
137Abnormalities of placenta or umbilical cord (HP:0001194)1.62539098
138Muscle stiffness (HP:0003552)1.62442939

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK26.25665198
2BUB15.19184101
3SMG15.18036117
4NME24.70548074
5WEE13.87616610
6TAF13.57548163
7EIF2AK13.23076327
8TLK13.08421872
9STK163.04851315
10SRPK12.68130253
11CDC72.59301018
12TESK22.46134019
13VRK12.44904785
14PLK42.10394909
15PIM21.96977964
16EIF2AK31.96567584
17PRPF4B1.86076980
18NME11.85517721
19TSSK61.84259721
20TRIB31.74784729
21DYRK31.67133375
22RPS6KB21.63649439
23PLK11.56513852
24CDK71.52006852
25RPS6KA41.50310557
26TTK1.49319642
27KDR1.49210835
28MKNK11.48733496
29PRKD31.45071417
30MST41.43897294
31NEK21.43681231
32AURKB1.43135183
33BRSK21.39459414
34EPHA21.33857148
35AURKA1.31131562
36MAP3K111.27327705
37PBK1.27322585
38ICK1.26408454
39PASK1.26187934
40ACVR1B1.21724290
41LRRK21.19507827
42DAPK11.16802324
43ATR1.13341266
44TESK11.12384966
45PAK41.10473309
46NUAK11.09919063
47MAP3K81.08701502
48IRAK31.06473137
49MAPKAPK51.04137702
50MAP4K11.01558212
51MKNK21.00772681
52PLK30.99456213
53ZAK0.96236560
54BRAF0.96199692
55STK100.96040804
56CHEK20.94247168
57ILK0.90868465
58TGFBR10.88853125
59RPS6KA50.87506071
60DYRK20.87439320
61CSNK2A20.85252318
62BRSK10.83822526
63NEK10.83473907
64PIM10.81269929
65PAK10.81222161
66CSNK2A10.80104204
67IRAK40.80022057
68CDK80.79132282
69PNCK0.76223451
70CHEK10.75969569
71LIMK10.75202397
72MELK0.73760716
73ABL20.72167821
74CDK90.71186798
75CDK40.71043287
76STK40.70090117
77EIF2AK20.68403709
78PRKCI0.66961709
79MAPK110.66405374
80CSNK1G30.66292198
81MAP3K100.64521683
82BLK0.61861024
83GRK60.60061015
84ARAF0.57113461
85PDK20.57075324
86BCKDK0.57003847
87CDK190.54611190
88DAPK30.54467948
89CDK20.54436068
90CSNK1A1L0.52634840
91SCYL20.50104603
92MAPKAPK30.47962118
93ATM0.47113870
94ZAP700.45956290
95BTK0.44408219
96IKBKB0.43839254
97ERN10.43002558
98AKT20.42680930
99CDK120.42676340
100CLK10.42399396
101MAP3K130.41331254
102CSNK1G10.41159616
103MAP2K20.40771648
104TEC0.40480531
105NLK0.38814652
106LATS20.38460108
107MAP3K30.37732332
108IRAK20.37411042
109TAOK20.36106779
110CCNB10.35639265
111CDK10.34797956
112CDK60.34515215
113EEF2K0.33692203
114CDK11A0.32212745
115TXK0.31622036
116CSNK1E0.30614317
117YES10.30480650
118MYLK0.29435596
119IRAK10.29401639
120ALK0.29271975
121FLT30.28647901
122LYN0.28243843
123FGFR40.28148585
124SIK10.26571009
125GRK50.26476522
126MST1R0.26233480
127MTOR0.25910239
128MAP3K120.25476197
129TYK20.24348828

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030106.30002618
2Proteasome_Homo sapiens_hsa030504.20594554
3DNA replication_Homo sapiens_hsa030304.09963152
4RNA polymerase_Homo sapiens_hsa030203.92552517
5Mismatch repair_Homo sapiens_hsa034303.50207412
6Spliceosome_Homo sapiens_hsa030403.33567121
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.19646883
8Pyrimidine metabolism_Homo sapiens_hsa002402.70486402
9Homologous recombination_Homo sapiens_hsa034402.61746445
10RNA transport_Homo sapiens_hsa030132.57321132
11Nucleotide excision repair_Homo sapiens_hsa034202.55160966
12Oxidative phosphorylation_Homo sapiens_hsa001902.54097729
13Base excision repair_Homo sapiens_hsa034102.48057731
14Parkinsons disease_Homo sapiens_hsa050122.38316172
15One carbon pool by folate_Homo sapiens_hsa006701.98695382
16Huntingtons disease_Homo sapiens_hsa050161.96471588
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.87991892
18Protein export_Homo sapiens_hsa030601.87004493
19Cell cycle_Homo sapiens_hsa041101.77179218
20Fanconi anemia pathway_Homo sapiens_hsa034601.73318291
21RNA degradation_Homo sapiens_hsa030181.68737362
22Basal transcription factors_Homo sapiens_hsa030221.68086048
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.66528175
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.50004269
25Non-homologous end-joining_Homo sapiens_hsa034501.49045872
26Alzheimers disease_Homo sapiens_hsa050101.48977473
27Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.43541728
28Purine metabolism_Homo sapiens_hsa002301.35118117
29p53 signaling pathway_Homo sapiens_hsa041151.22769117
30mRNA surveillance pathway_Homo sapiens_hsa030151.16370427
31Epstein-Barr virus infection_Homo sapiens_hsa051691.12731230
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.12492601
33Sulfur relay system_Homo sapiens_hsa041221.07947910
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.99016280
35Pyruvate metabolism_Homo sapiens_hsa006200.94719776
36Folate biosynthesis_Homo sapiens_hsa007900.93606755
37Systemic lupus erythematosus_Homo sapiens_hsa053220.91386658
38Sulfur metabolism_Homo sapiens_hsa009200.80489566
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.72322306
40Glutathione metabolism_Homo sapiens_hsa004800.71690432
41Fatty acid elongation_Homo sapiens_hsa000620.67636338
42Antigen processing and presentation_Homo sapiens_hsa046120.66854651
43Cardiac muscle contraction_Homo sapiens_hsa042600.66809297
44Cysteine and methionine metabolism_Homo sapiens_hsa002700.65259336
45Primary immunodeficiency_Homo sapiens_hsa053400.64374557
46Herpes simplex infection_Homo sapiens_hsa051680.63999821
47Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.61860116
48Pentose phosphate pathway_Homo sapiens_hsa000300.60897959
49Cyanoamino acid metabolism_Homo sapiens_hsa004600.60164176
50Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.60149443
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.57645931
52Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.56928275
53Viral carcinogenesis_Homo sapiens_hsa052030.54621311
54Chronic myeloid leukemia_Homo sapiens_hsa052200.54389863
55Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.53255806
56Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.52898563
57Non-small cell lung cancer_Homo sapiens_hsa052230.52071632
58Drug metabolism - other enzymes_Homo sapiens_hsa009830.50507341
59Central carbon metabolism in cancer_Homo sapiens_hsa052300.50258110
60Pancreatic cancer_Homo sapiens_hsa052120.47524744
61HTLV-I infection_Homo sapiens_hsa051660.45191061
62Oocyte meiosis_Homo sapiens_hsa041140.43184462
63Metabolic pathways_Homo sapiens_hsa011000.43101907
64Biosynthesis of amino acids_Homo sapiens_hsa012300.40817376
65Thyroid cancer_Homo sapiens_hsa052160.38246923
66Legionellosis_Homo sapiens_hsa051340.36347533
67Other glycan degradation_Homo sapiens_hsa005110.34566091
68Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.33435542
69Colorectal cancer_Homo sapiens_hsa052100.31929369
70Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.30744795
71Pentose and glucuronate interconversions_Homo sapiens_hsa000400.30325187
72Arachidonic acid metabolism_Homo sapiens_hsa005900.29704292
73Shigellosis_Homo sapiens_hsa051310.27977857
74Allograft rejection_Homo sapiens_hsa053300.27857817
75Apoptosis_Homo sapiens_hsa042100.27664817
76N-Glycan biosynthesis_Homo sapiens_hsa005100.27246104
77Asthma_Homo sapiens_hsa053100.26597169
78Alcoholism_Homo sapiens_hsa050340.25996876
79Basal cell carcinoma_Homo sapiens_hsa052170.25574136
80Measles_Homo sapiens_hsa051620.25303437
81Graft-versus-host disease_Homo sapiens_hsa053320.24755846
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.24689956
83Hematopoietic cell lineage_Homo sapiens_hsa046400.23902380
84NF-kappa B signaling pathway_Homo sapiens_hsa040640.22073252
85Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21724210
86Carbon metabolism_Homo sapiens_hsa012000.19771717
87Autoimmune thyroid disease_Homo sapiens_hsa053200.19157794
88Vitamin B6 metabolism_Homo sapiens_hsa007500.18138264
89Transcriptional misregulation in cancer_Homo sapiens_hsa052020.18017938
90Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.17018159
91Small cell lung cancer_Homo sapiens_hsa052220.16673630
92Vibrio cholerae infection_Homo sapiens_hsa051100.16652890
93Vitamin digestion and absorption_Homo sapiens_hsa049770.16197579
94Selenocompound metabolism_Homo sapiens_hsa004500.15850875
95Bladder cancer_Homo sapiens_hsa052190.15347117
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.15295133
97TGF-beta signaling pathway_Homo sapiens_hsa043500.15078760
98B cell receptor signaling pathway_Homo sapiens_hsa046620.14987616
99Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.14943042
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.13892166
101Arginine and proline metabolism_Homo sapiens_hsa003300.13749172
102Melanoma_Homo sapiens_hsa052180.13357280
103Prostate cancer_Homo sapiens_hsa052150.13301371
104Notch signaling pathway_Homo sapiens_hsa043300.13219574
105SNARE interactions in vesicular transport_Homo sapiens_hsa041300.12997485
106MicroRNAs in cancer_Homo sapiens_hsa052060.12586668
107Arginine biosynthesis_Homo sapiens_hsa002200.12388942
108Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.12244599
109Endometrial cancer_Homo sapiens_hsa052130.11915362
110Hepatitis B_Homo sapiens_hsa051610.11883068
111Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.11615638
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.11451190
113Viral myocarditis_Homo sapiens_hsa054160.10635135
114Tyrosine metabolism_Homo sapiens_hsa003500.09630235
115Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.08944108
116Steroid biosynthesis_Homo sapiens_hsa001000.08912036
117Hedgehog signaling pathway_Homo sapiens_hsa043400.08896479
118HIF-1 signaling pathway_Homo sapiens_hsa040660.08233699
119Pathways in cancer_Homo sapiens_hsa052000.07997504
120RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.07785144
121Hippo signaling pathway_Homo sapiens_hsa043900.07737454
122Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.07385045
123Acute myeloid leukemia_Homo sapiens_hsa052210.07297745
124Linoleic acid metabolism_Homo sapiens_hsa005910.07101540
125Fructose and mannose metabolism_Homo sapiens_hsa000510.06351215
126Galactose metabolism_Homo sapiens_hsa000520.06148398

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