

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of isotype switching to IgG isotypes (GO:0048302) | 7.24622411 |
| 2 | activation of MAPKKK activity (GO:0000185) | 6.74922621 |
| 3 | lens fiber cell development (GO:0070307) | 6.57008698 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 6.49583676 |
| 5 | viral transcription (GO:0019083) | 5.95647611 |
| 6 | leukocyte aggregation (GO:0070486) | 5.80008596 |
| 7 | translational termination (GO:0006415) | 5.63517625 |
| 8 | positive regulation of isotype switching (GO:0045830) | 4.99426704 |
| 9 | translational elongation (GO:0006414) | 4.67137858 |
| 10 | positive regulation of defense response to virus by host (GO:0002230) | 4.59390695 |
| 11 | activated T cell proliferation (GO:0050798) | 4.59331651 |
| 12 | dopamine transport (GO:0015872) | 4.51547352 |
| 13 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.50213418 |
| 14 | protein targeting to ER (GO:0045047) | 4.49575648 |
| 15 | cotranslational protein targeting to membrane (GO:0006613) | 4.44101035 |
| 16 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.41945366 |
| 17 | positive regulation of DNA recombination (GO:0045911) | 4.34617023 |
| 18 | ribosomal small subunit biogenesis (GO:0042274) | 4.32885001 |
| 19 | ribosomal small subunit assembly (GO:0000028) | 4.31746855 |
| 20 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.25709128 |
| 21 | viral life cycle (GO:0019058) | 4.24863681 |
| 22 | cellular protein complex disassembly (GO:0043624) | 4.24157208 |
| 23 | neurofilament cytoskeleton organization (GO:0060052) | 4.22481242 |
| 24 | protein localization to endoplasmic reticulum (GO:0070972) | 4.17907257 |
| 25 | positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) | 4.16772214 |
| 26 | regulation of DNA methylation (GO:0044030) | 4.04074419 |
| 27 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.03468870 |
| 28 | glyoxylate metabolic process (GO:0046487) | 3.98442213 |
| 29 | maturation of SSU-rRNA (GO:0030490) | 3.85295109 |
| 30 | ATP synthesis coupled proton transport (GO:0015986) | 3.80509386 |
| 31 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.80509386 |
| 32 | interferon-gamma production (GO:0032609) | 3.77546872 |
| 33 | glycoprotein catabolic process (GO:0006516) | 3.77392162 |
| 34 | mast cell activation (GO:0045576) | 3.70451908 |
| 35 | DNA deamination (GO:0045006) | 3.64117556 |
| 36 | male meiosis (GO:0007140) | 3.63647941 |
| 37 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.57414490 |
| 38 | positive regulation of B cell mediated immunity (GO:0002714) | 3.57414490 |
| 39 | leukotriene biosynthetic process (GO:0019370) | 3.51694324 |
| 40 | positive regulation of immunoglobulin production (GO:0002639) | 3.46741706 |
| 41 | mast cell degranulation (GO:0043303) | 3.42912664 |
| 42 | mast cell activation involved in immune response (GO:0002279) | 3.42912664 |
| 43 | protein complex disassembly (GO:0043241) | 3.40841299 |
| 44 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 3.39154744 |
| 45 | arginine catabolic process (GO:0006527) | 3.32130227 |
| 46 | cellular response to exogenous dsRNA (GO:0071360) | 3.28554048 |
| 47 | organic cation transport (GO:0015695) | 3.25220445 |
| 48 | negative regulation of telomere maintenance (GO:0032205) | 3.23829505 |
| 49 | translational initiation (GO:0006413) | 3.22935236 |
| 50 | meiotic chromosome segregation (GO:0045132) | 3.22230916 |
| 51 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.19766150 |
| 52 | regulation of telomere maintenance via telomerase (GO:0032210) | 3.17256320 |
| 53 | macromolecular complex disassembly (GO:0032984) | 3.15342022 |
| 54 | nucleotide-binding oligomerization domain containing signaling pathway (GO:0070423) | 3.14546497 |
| 55 | piRNA metabolic process (GO:0034587) | 3.13024336 |
| 56 | thyroid hormone generation (GO:0006590) | 3.09090011 |
| 57 | positive regulation of signal transduction by p53 class mediator (GO:1901798) | 3.08020334 |
| 58 | behavioral response to nicotine (GO:0035095) | 3.07361978 |
| 59 | base-excision repair, AP site formation (GO:0006285) | 3.04341439 |
| 60 | rRNA transcription (GO:0009303) | 3.04104982 |
| 61 | lymphocyte migration (GO:0072676) | 3.02495377 |
| 62 | protein targeting to membrane (GO:0006612) | 3.01334760 |
| 63 | mRNA catabolic process (GO:0006402) | 2.96045852 |
| 64 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 2.95387391 |
| 65 | regulation of defense response to virus by host (GO:0050691) | 2.94166080 |
| 66 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.87325299 |
| 67 | NADH dehydrogenase complex assembly (GO:0010257) | 2.87325299 |
| 68 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.87325299 |
| 69 | nucleobase biosynthetic process (GO:0046112) | 2.86097074 |
| 70 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.85576612 |
| 71 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.85576612 |
| 72 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.85157331 |
| 73 | lysosome localization (GO:0032418) | 2.84164481 |
| 74 | inner mitochondrial membrane organization (GO:0007007) | 2.78263668 |
| 75 | catecholamine transport (GO:0051937) | 2.76197142 |
| 76 | pattern specification involved in kidney development (GO:0061004) | 2.76154482 |
| 77 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.75369009 |
| 78 | UMP biosynthetic process (GO:0006222) | 2.75369009 |
| 79 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.75369009 |
| 80 | UMP metabolic process (GO:0046049) | 2.75369009 |
| 81 | forebrain morphogenesis (GO:0048853) | 2.71669423 |
| 82 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.69332316 |
| 83 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.68744524 |
| 84 | arginine metabolic process (GO:0006525) | 2.67106575 |
| 85 | positive regulation of T cell cytokine production (GO:0002726) | 2.66129915 |
| 86 | regulation of appetite (GO:0032098) | 2.64828460 |
| 87 | thyroid hormone metabolic process (GO:0042403) | 2.63805682 |
| 88 | induction of positive chemotaxis (GO:0050930) | 2.63180095 |
| 89 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.61876006 |
| 90 | termination of RNA polymerase III transcription (GO:0006386) | 2.61876006 |
| 91 | kidney morphogenesis (GO:0060993) | 2.60051298 |
| 92 | DNA methylation involved in gamete generation (GO:0043046) | 2.59965907 |
| 93 | RNA catabolic process (GO:0006401) | 2.59921460 |
| 94 | drug transmembrane transport (GO:0006855) | 2.59230955 |
| 95 | sulfate transmembrane transport (GO:1902358) | 2.57678083 |
| 96 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.56580902 |
| 97 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.54081875 |
| 98 | maintenance of protein location in nucleus (GO:0051457) | 2.53858288 |
| 99 | protein-cofactor linkage (GO:0018065) | 2.52114354 |
| 100 | cytolysis (GO:0019835) | 2.52099242 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 4.37337380 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.22345893 |
| 3 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 3.88537239 |
| 4 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.59934087 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49806119 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.46042330 |
| 7 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.26603557 |
| 8 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.23968914 |
| 9 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 2.22369142 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.15713174 |
| 11 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.08233410 |
| 12 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.00535868 |
| 13 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.82625650 |
| 14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.74521481 |
| 15 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.72772806 |
| 16 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.72655209 |
| 17 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.72523135 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.70854861 |
| 19 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.69462964 |
| 20 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.65489468 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.63842739 |
| 22 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.62154766 |
| 23 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.62003026 |
| 24 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.57250197 |
| 25 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.56697300 |
| 26 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.53603113 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.50513734 |
| 28 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.50154163 |
| 29 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.49445447 |
| 30 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.49416646 |
| 31 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.47258122 |
| 32 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.46418175 |
| 33 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.45986139 |
| 34 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45651962 |
| 35 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.39302375 |
| 36 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.37496462 |
| 37 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.36736551 |
| 38 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.35686793 |
| 39 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.34983482 |
| 40 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.32538270 |
| 41 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.31263591 |
| 42 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.30593200 |
| 43 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.27775915 |
| 44 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.26578394 |
| 45 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.26082592 |
| 46 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.25558494 |
| 47 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.25505143 |
| 48 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.23652394 |
| 49 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.22197085 |
| 50 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.21116416 |
| 51 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20754903 |
| 52 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.20562689 |
| 53 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.20562689 |
| 54 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.19762748 |
| 55 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.18202438 |
| 56 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.17026090 |
| 57 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.16057383 |
| 58 | ERA_21632823_ChIP-Seq_H3396_Human | 1.16014446 |
| 59 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.15809365 |
| 60 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.15515427 |
| 61 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.13510189 |
| 62 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.13115809 |
| 63 | NCOR_22424771_ChIP-Seq_293T_Human | 1.12908622 |
| 64 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.12737415 |
| 65 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.12737415 |
| 66 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.12612204 |
| 67 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.12463583 |
| 68 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.12421201 |
| 69 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.12143141 |
| 70 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.09523262 |
| 71 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.08566291 |
| 72 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.08122435 |
| 73 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.04176927 |
| 74 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.03821824 |
| 75 | SA1_27219007_Chip-Seq_Bcells_Human | 1.02740609 |
| 76 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.01353991 |
| 77 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.01231708 |
| 78 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.00164165 |
| 79 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.98972782 |
| 80 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.98829037 |
| 81 | AR_20517297_ChIP-Seq_VCAP_Human | 0.98386731 |
| 82 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.97336195 |
| 83 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.97307203 |
| 84 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.97288613 |
| 85 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.97288613 |
| 86 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96696694 |
| 87 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.95587119 |
| 88 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.94800055 |
| 89 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.93466352 |
| 90 | GATA3_26560356_Chip-Seq_TH2_Human | 0.93215135 |
| 91 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.93129407 |
| 92 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.92492807 |
| 93 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.91588818 |
| 94 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.91012857 |
| 95 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.90767885 |
| 96 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.90040917 |
| 97 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.90040917 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.89508197 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.88909550 |
| 100 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.88590393 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002132_abnormal_respiratory_system | 4.97557469 |
| 2 | MP0006082_CNS_inflammation | 4.70245873 |
| 3 | MP0005623_abnormal_meninges_morphology | 3.96055400 |
| 4 | MP0005671_abnormal_response_to | 3.81884606 |
| 5 | MP0009379_abnormal_foot_pigmentation | 3.64657357 |
| 6 | MP0008995_early_reproductive_senescence | 2.79264121 |
| 7 | MP0000858_altered_metastatic_potential | 2.53074798 |
| 8 | MP0002876_abnormal_thyroid_physiology | 2.33664264 |
| 9 | MP0003786_premature_aging | 2.25242474 |
| 10 | MP0005408_hypopigmentation | 2.19106955 |
| 11 | MP0001873_stomach_inflammation | 2.10081970 |
| 12 | MP0006292_abnormal_olfactory_placode | 2.08230572 |
| 13 | MP0000013_abnormal_adipose_tissue | 1.96600734 |
| 14 | MP0004142_abnormal_muscle_tone | 1.91995679 |
| 15 | MP0009384_cardiac_valve_regurgitation | 1.76002417 |
| 16 | MP0004885_abnormal_endolymph | 1.75073433 |
| 17 | MP0001800_abnormal_humoral_immune | 1.69186687 |
| 18 | MP0003787_abnormal_imprinting | 1.67768824 |
| 19 | MP0000750_abnormal_muscle_regeneration | 1.66234532 |
| 20 | MP0002638_abnormal_pupillary_reflex | 1.63257134 |
| 21 | MP0002837_dystrophic_cardiac_calcinosis | 1.60058881 |
| 22 | MP0002938_white_spotting | 1.59635230 |
| 23 | MP0001986_abnormal_taste_sensitivity | 1.58495778 |
| 24 | MP0008775_abnormal_heart_ventricle | 1.53974936 |
| 25 | MP0008875_abnormal_xenobiotic_pharmacok | 1.51773265 |
| 26 | MP0006276_abnormal_autonomic_nervous | 1.51714696 |
| 27 | MP0002163_abnormal_gland_morphology | 1.50865262 |
| 28 | MP0003763_abnormal_thymus_physiology | 1.49531564 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.49481036 |
| 30 | MP0001968_abnormal_touch/_nociception | 1.46327416 |
| 31 | MP0009785_altered_susceptibility_to | 1.37791369 |
| 32 | MP0003646_muscle_fatigue | 1.37608908 |
| 33 | MP0005645_abnormal_hypothalamus_physiol | 1.36374970 |
| 34 | MP0009764_decreased_sensitivity_to | 1.29695421 |
| 35 | MP0002102_abnormal_ear_morphology | 1.27743704 |
| 36 | MP0001905_abnormal_dopamine_level | 1.26824063 |
| 37 | MP0009333_abnormal_splenocyte_physiolog | 1.22100286 |
| 38 | MP0005377_hearing/vestibular/ear_phenot | 1.20061323 |
| 39 | MP0003878_abnormal_ear_physiology | 1.20061323 |
| 40 | MP0002736_abnormal_nociception_after | 1.19019331 |
| 41 | MP0005000_abnormal_immune_tolerance | 1.16154116 |
| 42 | MP0002653_abnormal_ependyma_morphology | 1.15926580 |
| 43 | MP0002723_abnormal_immune_serum | 1.12118439 |
| 44 | MP0010155_abnormal_intestine_physiology | 1.10006792 |
| 45 | MP0002405_respiratory_system_inflammati | 1.09116371 |
| 46 | MP0009697_abnormal_copulation | 1.09036709 |
| 47 | MP0008877_abnormal_DNA_methylation | 1.06354754 |
| 48 | MP0005167_abnormal_blood-brain_barrier | 1.03193782 |
| 49 | MP0006072_abnormal_retinal_apoptosis | 1.00277831 |
| 50 | MP0005423_abnormal_somatic_nervous | 0.98174315 |
| 51 | MP0005025_abnormal_response_to | 0.94307468 |
| 52 | MP0002138_abnormal_hepatobiliary_system | 0.94090501 |
| 53 | MP0003122_maternal_imprinting | 0.92656815 |
| 54 | MP0001835_abnormal_antigen_presentation | 0.92380650 |
| 55 | MP0002067_abnormal_sensory_capabilities | 0.91858002 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 0.91503369 |
| 57 | MP0002420_abnormal_adaptive_immunity | 0.91206135 |
| 58 | MP0001663_abnormal_digestive_system | 0.90012415 |
| 59 | MP0001819_abnormal_immune_cell | 0.89125388 |
| 60 | MP0003011_delayed_dark_adaptation | 0.88290221 |
| 61 | MP0002272_abnormal_nervous_system | 0.87139312 |
| 62 | MP0004742_abnormal_vestibular_system | 0.86527142 |
| 63 | MP0004947_skin_inflammation | 0.86459258 |
| 64 | MP0003880_abnormal_central_pattern | 0.86034349 |
| 65 | MP0000762_abnormal_tongue_morphology | 0.85791638 |
| 66 | MP0002277_abnormal_respiratory_mucosa | 0.85321674 |
| 67 | MP0005195_abnormal_posterior_eye | 0.85045305 |
| 68 | MP0003866_abnormal_defecation | 0.84906751 |
| 69 | MP0008469_abnormal_protein_level | 0.83523778 |
| 70 | MP0008872_abnormal_physiological_respon | 0.83305655 |
| 71 | MP0003186_abnormal_redox_activity | 0.83282729 |
| 72 | MP0009745_abnormal_behavioral_response | 0.83118185 |
| 73 | MP0002933_joint_inflammation | 0.82187913 |
| 74 | MP0005379_endocrine/exocrine_gland_phen | 0.82119010 |
| 75 | MP0008770_decreased_survivor_rate | 0.82085390 |
| 76 | MP0005410_abnormal_fertilization | 0.81175173 |
| 77 | MP0003252_abnormal_bile_duct | 0.79972574 |
| 78 | MP0003638_abnormal_response/metabolism_ | 0.79098472 |
| 79 | MP0003136_yellow_coat_color | 0.78192426 |
| 80 | MP0000685_abnormal_immune_system | 0.77304792 |
| 81 | MP0001790_abnormal_immune_system | 0.76320436 |
| 82 | MP0005387_immune_system_phenotype | 0.76320436 |
| 83 | MP0002452_abnormal_antigen_presenting | 0.76199819 |
| 84 | MP0004130_abnormal_muscle_cell | 0.75378919 |
| 85 | MP0004145_abnormal_muscle_electrophysio | 0.74513066 |
| 86 | MP0001119_abnormal_female_reproductive | 0.74245571 |
| 87 | MP0003718_maternal_effect | 0.73345048 |
| 88 | MP0002735_abnormal_chemical_nociception | 0.72033548 |
| 89 | MP0000049_abnormal_middle_ear | 0.71294055 |
| 90 | MP0002184_abnormal_innervation | 0.70294760 |
| 91 | MP0005084_abnormal_gallbladder_morpholo | 0.70018500 |
| 92 | MP0010307_abnormal_tumor_latency | 0.69567253 |
| 93 | MP0000230_abnormal_systemic_arterial | 0.69122415 |
| 94 | MP0002572_abnormal_emotion/affect_behav | 0.69093243 |
| 95 | MP0009046_muscle_twitch | 0.68707920 |
| 96 | MP0001485_abnormal_pinna_reflex | 0.65802758 |
| 97 | MP0005646_abnormal_pituitary_gland | 0.65586443 |
| 98 | MP0003121_genomic_imprinting | 0.65327110 |
| 99 | MP0004147_increased_porphyrin_level | 0.63438607 |
| 100 | MP0001845_abnormal_inflammatory_respons | 0.63261489 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Retinal atrophy (HP:0001105) | 7.30658195 |
| 2 | Cerebellar dysplasia (HP:0007033) | 7.04791883 |
| 3 | Type II lissencephaly (HP:0007260) | 6.60332828 |
| 4 | Abnormality of pyrimidine metabolism (HP:0004353) | 5.68237863 |
| 5 | Hypoplasia of the pons (HP:0012110) | 5.26841901 |
| 6 | Retinal dysplasia (HP:0007973) | 5.14678263 |
| 7 | Abnormality of DNA repair (HP:0003254) | 4.96323371 |
| 8 | Abnormality of the pons (HP:0007361) | 4.89789142 |
| 9 | Reticulocytopenia (HP:0001896) | 4.79865300 |
| 10 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 4.41504532 |
| 11 | Buphthalmos (HP:0000557) | 4.11051596 |
| 12 | Nasal polyposis (HP:0100582) | 4.05554530 |
| 13 | Fatigue (HP:0012378) | 4.03510637 |
| 14 | Abolished electroretinogram (ERG) (HP:0000550) | 4.03152524 |
| 15 | Increased IgM level (HP:0003496) | 3.87206050 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.85116060 |
| 17 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 3.71808083 |
| 18 | Duplicated collecting system (HP:0000081) | 3.60366752 |
| 19 | Abnormality of the renal collecting system (HP:0004742) | 3.45468815 |
| 20 | Abnormality of the nasal mucosa (HP:0000433) | 3.27804944 |
| 21 | Megalocornea (HP:0000485) | 3.14134271 |
| 22 | IgG deficiency (HP:0004315) | 3.08541910 |
| 23 | Pallor (HP:0000980) | 3.06251497 |
| 24 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.04171519 |
| 25 | Absent thumb (HP:0009777) | 2.84843008 |
| 26 | Zonular cataract (HP:0010920) | 2.72591463 |
| 27 | Severe muscular hypotonia (HP:0006829) | 2.66518319 |
| 28 | Entropion (HP:0000621) | 2.65431876 |
| 29 | Difficulty climbing stairs (HP:0003551) | 2.62284904 |
| 30 | Molar tooth sign on MRI (HP:0002419) | 2.61721573 |
| 31 | Abnormality of midbrain morphology (HP:0002418) | 2.61721573 |
| 32 | Nephronophthisis (HP:0000090) | 2.61551837 |
| 33 | Lissencephaly (HP:0001339) | 2.55863456 |
| 34 | Colon cancer (HP:0003003) | 2.48960038 |
| 35 | Chromsome breakage (HP:0040012) | 2.48145832 |
| 36 | Macrocytic anemia (HP:0001972) | 2.47391177 |
| 37 | Abnormality of T cells (HP:0002843) | 2.40760350 |
| 38 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.39788088 |
| 39 | Oral leukoplakia (HP:0002745) | 2.36694723 |
| 40 | Eosinophilia (HP:0001880) | 2.35363495 |
| 41 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.33731141 |
| 42 | Stomach cancer (HP:0012126) | 2.24761917 |
| 43 | Congenital glaucoma (HP:0001087) | 2.23212880 |
| 44 | Ectopic kidney (HP:0000086) | 2.22655080 |
| 45 | Pancreatic fibrosis (HP:0100732) | 2.19509546 |
| 46 | Abnormality of T cell physiology (HP:0011840) | 2.19186813 |
| 47 | Pachygyria (HP:0001302) | 2.16956477 |
| 48 | Abnormality of the renal medulla (HP:0100957) | 2.16386774 |
| 49 | Abnormality of the renal cortex (HP:0011035) | 2.10263900 |
| 50 | Erythroderma (HP:0001019) | 2.09618851 |
| 51 | Conical tooth (HP:0000698) | 2.09591464 |
| 52 | 3-Methylglutaconic aciduria (HP:0003535) | 2.08431309 |
| 53 | Abnormality of eosinophils (HP:0001879) | 2.06078340 |
| 54 | Stenosis of the external auditory canal (HP:0000402) | 2.05819651 |
| 55 | Aplastic anemia (HP:0001915) | 2.03766983 |
| 56 | Abnormal drinking behavior (HP:0030082) | 2.02928452 |
| 57 | Polydipsia (HP:0001959) | 2.02928452 |
| 58 | Thrombocytosis (HP:0001894) | 2.01642766 |
| 59 | Poikiloderma (HP:0001029) | 2.00280483 |
| 60 | Meningocele (HP:0002435) | 1.99745223 |
| 61 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.97807425 |
| 62 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 1.97091553 |
| 63 | Ureteral duplication (HP:0000073) | 1.95810919 |
| 64 | Papilledema (HP:0001085) | 1.93530145 |
| 65 | Pancreatic cysts (HP:0001737) | 1.93313475 |
| 66 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.93026397 |
| 67 | Agitation (HP:0000713) | 1.91352086 |
| 68 | Abnormality of T cell number (HP:0011839) | 1.90876919 |
| 69 | Hypergammaglobulinemia (HP:0010702) | 1.89624850 |
| 70 | Asplenia (HP:0001746) | 1.87476909 |
| 71 | Diaphragmatic weakness (HP:0009113) | 1.86111460 |
| 72 | Abnormality of nucleobase metabolism (HP:0010932) | 1.85313695 |
| 73 | Intellectual disability, profound (HP:0002187) | 1.84824406 |
| 74 | Polyuria (HP:0000103) | 1.83920741 |
| 75 | True hermaphroditism (HP:0010459) | 1.82480330 |
| 76 | Thyroid-stimulating hormone excess (HP:0002925) | 1.82479165 |
| 77 | Hypoproteinemia (HP:0003075) | 1.81814163 |
| 78 | Duplication of thumb phalanx (HP:0009942) | 1.81668427 |
| 79 | Increased serum pyruvate (HP:0003542) | 1.79389321 |
| 80 | Acute necrotizing encephalopathy (HP:0006965) | 1.77987468 |
| 81 | Hypoplasia of the brainstem (HP:0002365) | 1.77985262 |
| 82 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.77985262 |
| 83 | Fragile nails (HP:0001808) | 1.76441126 |
| 84 | Poikilocytosis (HP:0004447) | 1.76121097 |
| 85 | Medial flaring of the eyebrow (HP:0010747) | 1.75951432 |
| 86 | Keratitis (HP:0000491) | 1.75764954 |
| 87 | Pancytopenia (HP:0001876) | 1.75712062 |
| 88 | Stomatitis (HP:0010280) | 1.75630208 |
| 89 | Mesangial abnormality (HP:0001966) | 1.74940179 |
| 90 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.71905648 |
| 91 | Congenital stationary night blindness (HP:0007642) | 1.69892524 |
| 92 | Abnormality of the vitreous humor (HP:0004327) | 1.68831845 |
| 93 | Generalized muscle weakness (HP:0003324) | 1.66794838 |
| 94 | Myositis (HP:0100614) | 1.66754112 |
| 95 | Horseshoe kidney (HP:0000085) | 1.65475173 |
| 96 | Megaloblastic anemia (HP:0001889) | 1.63838782 |
| 97 | Hypoalbuminemia (HP:0003073) | 1.63725244 |
| 98 | Abnormal albumin level (HP:0012116) | 1.63725244 |
| 99 | Synostosis of carpal bones (HP:0005048) | 1.63530825 |
| 100 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.63119762 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 6.36710447 |
| 2 | TXK | 5.55005013 |
| 3 | MAP4K1 | 4.41982742 |
| 4 | MARK3 | 3.90626299 |
| 5 | BCKDK | 3.59991379 |
| 6 | STK10 | 3.41652395 |
| 7 | ITK | 3.19449900 |
| 8 | PTK2B | 3.06847942 |
| 9 | WNK4 | 2.54973131 |
| 10 | ZAP70 | 2.52660633 |
| 11 | PIM1 | 2.32183541 |
| 12 | CDK19 | 1.86924095 |
| 13 | PIK3CA | 1.71177323 |
| 14 | STK11 | 1.53964704 |
| 15 | STK39 | 1.52592470 |
| 16 | TIE1 | 1.50795817 |
| 17 | ADRBK2 | 1.44518519 |
| 18 | GRK1 | 1.43723158 |
| 19 | MAP4K2 | 1.33716609 |
| 20 | MAP3K12 | 1.30432155 |
| 21 | TLK1 | 1.25330256 |
| 22 | MUSK | 1.14912147 |
| 23 | GSK3A | 1.13859802 |
| 24 | INSRR | 1.12425096 |
| 25 | SYK | 1.05348715 |
| 26 | FRK | 1.03984111 |
| 27 | PINK1 | 0.99770577 |
| 28 | PRKG2 | 0.99463375 |
| 29 | TBK1 | 0.98581006 |
| 30 | FES | 0.98110038 |
| 31 | NUAK1 | 0.97336471 |
| 32 | CAMKK2 | 0.94055833 |
| 33 | DYRK2 | 0.93272648 |
| 34 | BMPR1B | 0.92922818 |
| 35 | PRKCH | 0.92430239 |
| 36 | MAPK7 | 0.91769158 |
| 37 | IKBKB | 0.87446876 |
| 38 | BTK | 0.80211871 |
| 39 | MYLK | 0.79500796 |
| 40 | NLK | 0.78368016 |
| 41 | TYRO3 | 0.76916222 |
| 42 | OXSR1 | 0.73649419 |
| 43 | WNK1 | 0.73434086 |
| 44 | MAP2K2 | 0.73025942 |
| 45 | CHEK2 | 0.72304423 |
| 46 | MAP3K7 | 0.72118129 |
| 47 | LCK | 0.71850816 |
| 48 | KDR | 0.64822883 |
| 49 | PRKCQ | 0.64379002 |
| 50 | DAPK3 | 0.58660660 |
| 51 | VRK1 | 0.56670051 |
| 52 | LYN | 0.56159338 |
| 53 | CSNK1A1 | 0.55296972 |
| 54 | OBSCN | 0.52849347 |
| 55 | STK16 | 0.52715065 |
| 56 | WNK3 | 0.52663023 |
| 57 | ZAK | 0.52656652 |
| 58 | LMTK2 | 0.51555586 |
| 59 | PRKCG | 0.51278258 |
| 60 | MAP3K13 | 0.50858019 |
| 61 | PIK3CG | 0.48768145 |
| 62 | TESK2 | 0.48752066 |
| 63 | CAMK1D | 0.47499431 |
| 64 | NTRK2 | 0.47279011 |
| 65 | PRKAA2 | 0.42928064 |
| 66 | SGK1 | 0.42188646 |
| 67 | IKBKE | 0.41808836 |
| 68 | RPS6KA5 | 0.40301692 |
| 69 | TEC | 0.40001569 |
| 70 | CAMKK1 | 0.39494556 |
| 71 | LRRK2 | 0.39024207 |
| 72 | CDK4 | 0.38817055 |
| 73 | MAPK15 | 0.38731512 |
| 74 | IGF1R | 0.37525291 |
| 75 | CSNK1G1 | 0.36342875 |
| 76 | HCK | 0.35278968 |
| 77 | ADRBK1 | 0.34140427 |
| 78 | PRKACA | 0.33797458 |
| 79 | KIT | 0.33426232 |
| 80 | GRK6 | 0.33405662 |
| 81 | CAMK1 | 0.33120623 |
| 82 | PRKCZ | 0.33094822 |
| 83 | PRKCA | 0.31881910 |
| 84 | PHKG2 | 0.31731826 |
| 85 | PHKG1 | 0.31731826 |
| 86 | CSNK1G3 | 0.31053247 |
| 87 | CSNK1A1L | 0.30554588 |
| 88 | GRK7 | 0.30404856 |
| 89 | RPS6KA6 | 0.28606481 |
| 90 | MAPK13 | 0.28418471 |
| 91 | DAPK1 | 0.27735291 |
| 92 | PRKCE | 0.27468584 |
| 93 | PRKACG | 0.26802060 |
| 94 | FYN | 0.26185782 |
| 95 | PRKCD | 0.25308321 |
| 96 | PKN1 | 0.23732640 |
| 97 | GRK5 | 0.22887436 |
| 98 | PIM2 | 0.22635829 |
| 99 | NME2 | 0.22452034 |
| 100 | CSNK1G2 | 0.22283151 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.87563922 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.58682846 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.16873352 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.94707983 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.72620997 |
| 6 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.52504413 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.41387372 |
| 8 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.41056713 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.11909234 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.08917360 |
| 11 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.92101203 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.87902130 |
| 13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.86292467 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.85299485 |
| 15 | Parkinsons disease_Homo sapiens_hsa05012 | 1.82735161 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.78157015 |
| 17 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.75764124 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.59567431 |
| 19 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.56612417 |
| 20 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.53479294 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.49849518 |
| 22 | Viral myocarditis_Homo sapiens_hsa05416 | 1.46318698 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.40583381 |
| 24 | Sulfur relay system_Homo sapiens_hsa04122 | 1.40123749 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.39519240 |
| 26 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.36584407 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.36505008 |
| 28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.33155881 |
| 29 | Leishmaniasis_Homo sapiens_hsa05140 | 1.29575042 |
| 30 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.28581929 |
| 31 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.23360511 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.20000448 |
| 33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.19818590 |
| 34 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.17228772 |
| 35 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14599020 |
| 36 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.07879670 |
| 37 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.02395268 |
| 38 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02302879 |
| 39 | Alzheimers disease_Homo sapiens_hsa05010 | 0.99105415 |
| 40 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.98623833 |
| 41 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.97732343 |
| 42 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.96221687 |
| 43 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.95848672 |
| 44 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.94868441 |
| 45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92471201 |
| 46 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.91468362 |
| 47 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.87193486 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 0.83925672 |
| 49 | Protein export_Homo sapiens_hsa03060 | 0.82689665 |
| 50 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.81678250 |
| 51 | Malaria_Homo sapiens_hsa05144 | 0.78379356 |
| 52 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75196847 |
| 53 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.74878438 |
| 54 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.73315167 |
| 55 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.72240550 |
| 56 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.72022527 |
| 57 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.71249556 |
| 58 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.70511220 |
| 59 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.70343602 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.70284491 |
| 61 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.69659121 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69244745 |
| 63 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.69097342 |
| 64 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65591429 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.65265005 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.65104639 |
| 67 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.64467962 |
| 68 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62359651 |
| 69 | Peroxisome_Homo sapiens_hsa04146 | 0.59432313 |
| 70 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.57557168 |
| 71 | Olfactory transduction_Homo sapiens_hsa04740 | 0.57492087 |
| 72 | Morphine addiction_Homo sapiens_hsa05032 | 0.57246069 |
| 73 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.55436239 |
| 74 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.53420152 |
| 75 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.52952117 |
| 76 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50003159 |
| 77 | Taste transduction_Homo sapiens_hsa04742 | 0.46750906 |
| 78 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46677804 |
| 79 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.46495994 |
| 80 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.44692565 |
| 81 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.44532773 |
| 82 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.44110752 |
| 83 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.41675731 |
| 84 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.40906390 |
| 85 | Insulin secretion_Homo sapiens_hsa04911 | 0.40005894 |
| 86 | Purine metabolism_Homo sapiens_hsa00230 | 0.37836890 |
| 87 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.37659861 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37234778 |
| 89 | Proteasome_Homo sapiens_hsa03050 | 0.36798457 |
| 90 | Homologous recombination_Homo sapiens_hsa03440 | 0.34554094 |
| 91 | Metabolic pathways_Homo sapiens_hsa01100 | 0.34550087 |
| 92 | Mineral absorption_Homo sapiens_hsa04978 | 0.32666574 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.32253874 |
| 94 | Base excision repair_Homo sapiens_hsa03410 | 0.31449777 |
| 95 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.30281588 |
| 96 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.29501178 |
| 97 | Salivary secretion_Homo sapiens_hsa04970 | 0.29383531 |
| 98 | Bile secretion_Homo sapiens_hsa04976 | 0.28414720 |
| 99 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.25358186 |
| 100 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.25219050 |

