RPL29P11

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of protein homooligomerization (GO:0032462)8.92504849
2T-helper 1 type immune response (GO:0042088)8.78044802
3protein targeting to peroxisome (GO:0006625)7.95281054
4establishment of protein localization to peroxisome (GO:0072663)7.95281054
5protein localization to peroxisome (GO:0072662)7.95281054
6lipopolysaccharide biosynthetic process (GO:0009103)7.53483733
7peroxisomal transport (GO:0043574)7.31775653
8histone H4-K12 acetylation (GO:0043983)7.20124153
9regulation of isotype switching to IgG isotypes (GO:0048302)6.96845904
10DNA deamination (GO:0045006)6.65662587
11lipopolysaccharide metabolic process (GO:0008653)6.59899377
12nucleotide transport (GO:0006862)6.15631534
13protein-cofactor linkage (GO:0018065)6.06920453
14rRNA catabolic process (GO:0016075)5.86977654
15positive regulation of isotype switching (GO:0045830)5.79256158
16antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.69880207
17negative regulation of glycogen biosynthetic process (GO:0045719)5.49204917
18intracellular protein transmembrane import (GO:0044743)5.42233314
19DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla5.29636661
20peroxisome organization (GO:0007031)5.24709390
21positive regulation of DNA recombination (GO:0045911)5.14617957
22spliceosomal snRNP assembly (GO:0000387)4.90003577
23DNA damage response, signal transduction resulting in transcription (GO:0042772)4.86022283
24antigen processing and presentation via MHC class Ib (GO:0002475)4.72098453
25positive regulation of interleukin-17 production (GO:0032740)4.67509793
26microtubule anchoring (GO:0034453)4.65180431
27regulation of telomere maintenance via telomerase (GO:0032210)4.61494908
28regulation of protein oligomerization (GO:0032459)4.40047393
29microglial cell activation (GO:0001774)4.37343834
30negative regulation of glycogen metabolic process (GO:0070874)4.37202140
31adaptation of signaling pathway (GO:0023058)4.35640175
32negative regulation of telomere maintenance (GO:0032205)4.31297187
33negative regulation of cell killing (GO:0031342)4.25568856
34negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.25568856
35intracellular protein transmembrane transport (GO:0065002)4.20284677
36regulation of energy homeostasis (GO:2000505)4.17667836
37extracellular regulation of signal transduction (GO:1900115)4.15738231
38extracellular negative regulation of signal transduction (GO:1900116)4.15738231
39RNA methylation (GO:0001510)4.12650213
40positive regulation of T cell mediated cytotoxicity (GO:0001916)4.03754764
41keratan sulfate biosynthetic process (GO:0018146)4.00348154
42lysine metabolic process (GO:0006553)3.95521568
43lysine catabolic process (GO:0006554)3.95521568
44macrophage chemotaxis (GO:0048246)3.89001251
45platelet dense granule organization (GO:0060155)3.77780703
46positive regulation of mast cell activation (GO:0033005)3.64569746
47RNA capping (GO:0036260)3.57672120
487-methylguanosine RNA capping (GO:0009452)3.57672120
49positive regulation of mast cell degranulation (GO:0043306)3.56928101
50positive regulation of mast cell activation involved in immune response (GO:0033008)3.56928101
51antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.55943767
52mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.53959194
53positive regulation of immunoglobulin mediated immune response (GO:0002891)3.51728782
54positive regulation of B cell mediated immunity (GO:0002714)3.51728782
55sleep (GO:0030431)3.48094864
56regulation of isotype switching (GO:0045191)3.46992830
57protein transmembrane transport (GO:0071806)3.45823757
58positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725)3.44213953
59macrophage activation involved in immune response (GO:0002281)3.39805943
60positive regulation of immunoglobulin production (GO:0002639)3.38553872
61histone H4-K5 acetylation (GO:0043981)3.38424854
62histone H4-K8 acetylation (GO:0043982)3.38424854
63cilium or flagellum-dependent cell motility (GO:0001539)3.33619534
64regulation of T cell mediated cytotoxicity (GO:0001914)3.33305081
65positive regulation of natural killer cell mediated immunity (GO:0002717)3.32893397
66regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)3.28000875
67nucleoside diphosphate phosphorylation (GO:0006165)3.26187215
68membrane docking (GO:0022406)3.22727763
69thrombin receptor signaling pathway (GO:0070493)3.12915890
70keratan sulfate metabolic process (GO:0042339)3.08789829
71ribosome assembly (GO:0042255)3.08764609
72negative regulation of telomerase activity (GO:0051974)3.08024487
73sulfation (GO:0051923)3.04373850
74antigen processing and presentation of endogenous antigen (GO:0019883)3.03823935
75ncRNA catabolic process (GO:0034661)3.00577828
76positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.90736461
77activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO2.89278125
78negative regulation of mast cell activation (GO:0033004)2.88959833
79glycerophospholipid catabolic process (GO:0046475)2.85728233
80triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.85386597
81positive regulation of leukocyte mediated immunity (GO:0002705)2.82054466
82ribonucleoprotein complex biogenesis (GO:0022613)2.80390748
83termination of RNA polymerase III transcription (GO:0006386)2.79103566
84transcription elongation from RNA polymerase III promoter (GO:0006385)2.79103566
85cellular protein complex disassembly (GO:0043624)2.78649356
86positive regulation of lymphocyte mediated immunity (GO:0002708)2.71397527
87ribosomal small subunit assembly (GO:0000028)2.69507187
88positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.68719910
89positive regulation of adaptive immune response based on somatic recombination of immune receptors b2.66339151
90regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.65707131
91regulation of natural killer cell mediated immunity (GO:0002715)2.65707131
92CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.65041830
93T-helper cell differentiation (GO:0042093)2.65041830
94aspartate family amino acid catabolic process (GO:0009068)2.64582664
95regulation of protein kinase A signaling (GO:0010738)2.61595265
96positive regulation vascular endothelial growth factor production (GO:0010575)2.61293711
97maturation of 5.8S rRNA (GO:0000460)15.8197312
98negative regulation of protein oligomerization (GO:0032460)12.4473934
99nucleotide transmembrane transport (GO:1901679)12.1826257
100protein import into peroxisome matrix (GO:0016558)11.6704795

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_21828071_ChIP-Seq_BEAS2B_Human6.35134057
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat5.99328195
3CHD7_19251738_ChIP-ChIP_MESCs_Mouse4.53713913
4NOTCH1_21737748_ChIP-Seq_TLL_Human3.81618637
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human3.56795544
6RBPJ_22232070_ChIP-Seq_NCS_Mouse3.34227661
7IKZF1_21737484_ChIP-ChIP_HCT116_Human3.08827762
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.89815211
9ZNF274_21170338_ChIP-Seq_K562_Hela2.85563844
10KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.85300058
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.68301092
12GABP_17652178_ChIP-ChIP_JURKAT_Human2.54736470
13YY1_21170310_ChIP-Seq_MESCs_Mouse2.53152578
14TDRD3_21172665_ChIP-Seq_MCF-7_Human2.51846119
15IRF1_19129219_ChIP-ChIP_H3396_Human2.38010906
16VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human2.24820382
17TP63_19390658_ChIP-ChIP_HaCaT_Human1.94885477
18GATA1_22025678_ChIP-Seq_K562_Human1.93134573
19IRF8_22096565_ChIP-ChIP_GC-B_Human1.92790870
20EST1_17652178_ChIP-ChIP_JURKAT_Human1.90079678
21VDR_22108803_ChIP-Seq_LS180_Human1.89083686
22CTBP1_25329375_ChIP-Seq_LNCAP_Human1.88130309
23HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82743225
24EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.78722768
25TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.78606011
26CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.74017130
27EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.72321807
28ETS1_20019798_ChIP-Seq_JURKAT_Human1.71891423
29EGR1_23403033_ChIP-Seq_LIVER_Mouse1.65937847
30EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.62645897
31SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.56459827
32BP1_19119308_ChIP-ChIP_Hs578T_Human1.51127869
33LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.48209929
34TAF2_19829295_ChIP-Seq_ESCs_Human1.48022734
35E2F4_17652178_ChIP-ChIP_JURKAT_Human1.44955363
36JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.42158455
37FOXP3_21729870_ChIP-Seq_TREG_Human1.41673078
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.41005873
39VDR_23849224_ChIP-Seq_CD4+_Human1.40206105
40ETV2_25802403_ChIP-Seq_MESCs_Mouse1.37822681
41FOXA1_27270436_Chip-Seq_PROSTATE_Human1.36626449
42FOXA1_25329375_ChIP-Seq_VCAP_Human1.36626449
43RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.30303154
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.30000974
45NANOG_20526341_ChIP-Seq_ESCs_Human1.26199105
46EWS_26573619_Chip-Seq_HEK293_Human1.25889672
47RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human1.24901663
48GBX2_23144817_ChIP-Seq_PC3_Human1.24513140
49SOX2_19829295_ChIP-Seq_ESCs_Human1.23111867
50NANOG_19829295_ChIP-Seq_ESCs_Human1.23111867
51GATA3_21878914_ChIP-Seq_MCF-7_Human1.22634452
52ELK1_19687146_ChIP-ChIP_HELA_Human1.21136095
53RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.20591653
54BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.17530346
55AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16376918
56MYC_18555785_ChIP-Seq_MESCs_Mouse1.11715028
57STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.08941487
58RUNX_20019798_ChIP-Seq_JUKART_Human1.08071547
59AR_20517297_ChIP-Seq_VCAP_Human1.07923036
60ELF1_20517297_ChIP-Seq_JURKAT_Human1.06745635
61BMI1_23680149_ChIP-Seq_NPCS_Mouse1.05285577
62E2F1_20622854_ChIP-Seq_HELA_Human1.03911786
63SOX2_18555785_ChIP-Seq_MESCs_Mouse1.02403957
64YY1_22570637_ChIP-Seq_MALME-3M_Human1.02348589
65DCP1A_22483619_ChIP-Seq_HELA_Human1.01233000
66ELK1_22589737_ChIP-Seq_MCF10A_Human1.01111640
67PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.00046408
68SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.98788683
69CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.96660895
70GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95638388
71P53_21459846_ChIP-Seq_SAOS-2_Human0.94303695
72FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.92050013
73FOXH1_21741376_ChIP-Seq_ESCs_Human0.91638539
74EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.91406899
75CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.90920733
76THAP11_20581084_ChIP-Seq_MESCs_Mouse0.90870446
77MYC_19829295_ChIP-Seq_ESCs_Human0.90742956
78SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.90738785
79NCOR_22424771_ChIP-Seq_293T_Human0.90426109
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.90116671
81IGF1R_20145208_ChIP-Seq_DFB_Human0.89976123
82SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.88468515
83CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.86084132
84STAT4_19710469_ChIP-ChIP_TH1__Mouse0.84832689
85SOX2_21211035_ChIP-Seq_LN229_Human0.84505169
86SCL_19346495_ChIP-Seq_HPC-7_Human0.84272564
87GATA3_26560356_Chip-Seq_TH2_Human0.84129367
88AR_25329375_ChIP-Seq_VCAP_Human0.83884219
89YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.83521775
90SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.83096857
91MYC_19030024_ChIP-ChIP_MESCs_Mouse0.82562272
92SRF_21415370_ChIP-Seq_HL-1_Mouse0.82516612
93EED_16625203_ChIP-ChIP_MESCs_Mouse0.81936733
94GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human0.81108592
95SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.80890417
96PCGF2_27294783_Chip-Seq_ESCs_Mouse0.80161758
97CRX_20693478_ChIP-Seq_RETINA_Mouse0.79908135
98BCL6_27268052_Chip-Seq_Bcells_Human0.79626895
99MYC_18358816_ChIP-ChIP_MESCs_Mouse0.79169497
100SALL4_22934838_ChIP-ChIP_CD34+_Human0.76852630

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006082_CNS_inflammation9.49743538
2MP0001873_stomach_inflammation4.93406363
3MP0001348_abnormal_lacrimal_gland4.66576642
4MP0002132_abnormal_respiratory_system4.01763228
5MP0001346_abnormal_lacrimal_gland3.95380709
6MP0002876_abnormal_thyroid_physiology3.53099129
7MP0003300_gastrointestinal_ulcer3.29852966
8MP0003690_abnormal_glial_cell3.12818942
9MP0002837_dystrophic_cardiac_calcinosis2.57954384
10MP0005671_abnormal_response_to2.28877698
11MP0009333_abnormal_splenocyte_physiolog2.03859485
12MP0002254_reproductive_system_inflammat10.2469368
13MP0003693_abnormal_embryo_hatching1.90127829
14MP0005310_abnormal_salivary_gland1.76984295
15MP0003950_abnormal_plasma_membrane1.72083838
16MP0002405_respiratory_system_inflammati1.55366514
17MP0005647_abnormal_sex_gland1.54697514
18MP0000685_abnormal_immune_system1.53445254
19MP0001984_abnormal_olfaction1.51329635
20MP0002277_abnormal_respiratory_mucosa1.47548812
21MP0000613_abnormal_salivary_gland1.44010330
22MP0003763_abnormal_thymus_physiology1.43663614
23MP0001663_abnormal_digestive_system1.24634717
24MP0005595_abnormal_vascular_smooth1.18929299
25MP0009785_altered_susceptibility_to1.16590300
26MP0001919_abnormal_reproductive_system1.11137603
27MP0005000_abnormal_immune_tolerance1.08367893
28MP0000920_abnormal_myelination1.02269224
29MP0006292_abnormal_olfactory_placode1.00730252
30MP0001915_intracranial_hemorrhage0.97404308
31MP0005166_decreased_susceptibility_to0.95802029
32MP0005389_reproductive_system_phenotype0.93712022
33MP0009046_muscle_twitch0.90614719
34MP0000858_altered_metastatic_potential0.90534191
35MP0010155_abnormal_intestine_physiology0.89303538
36MP0005197_abnormal_uvea_morphology0.88844782
37MP0001800_abnormal_humoral_immune0.88833667
38MP0001851_eye_inflammation0.87783095
39MP0004885_abnormal_endolymph0.87502523
40MP0003724_increased_susceptibility_to0.87369336
41MP0000631_abnormal_neuroendocrine_gland0.85888252
42MP0005381_digestive/alimentary_phenotyp0.85293484
43MP0005025_abnormal_response_to0.81767376
44MP0002163_abnormal_gland_morphology0.79779949
45MP0002693_abnormal_pancreas_physiology0.79425998
46MP0005645_abnormal_hypothalamus_physiol0.78869393
47MP0001119_abnormal_female_reproductive0.78119927
48MP0005448_abnormal_energy_balance0.77214853
49MP0001790_abnormal_immune_system0.76413764
50MP0005387_immune_system_phenotype0.76413764
51MP0003718_maternal_effect0.75057413
52MP0002138_abnormal_hepatobiliary_system0.75053369
53MP0002452_abnormal_antigen_presenting0.72663955
54MP0004883_abnormal_blood_vessel0.69983295
55MP0005167_abnormal_blood-brain_barrier0.69700832
56MP0000703_abnormal_thymus_morphology0.68602393
57MP0002420_abnormal_adaptive_immunity0.67976069
58MP0001819_abnormal_immune_cell0.65806746
59MP0002723_abnormal_immune_serum0.65138652
60MP0009765_abnormal_xenobiotic_induced0.64600842
61MP0003786_premature_aging0.62579554
62MP0002419_abnormal_innate_immunity0.62158000
63MP0003011_delayed_dark_adaptation0.59553827
64MP0000470_abnormal_stomach_morphology0.57696111
65MP0000465_gastrointestinal_hemorrhage0.57260790
66MP0000639_abnormal_adrenal_gland0.56274950
67MP0003183_abnormal_peptide_metabolism0.56270805
68MP0002102_abnormal_ear_morphology0.55513785
69MP0005646_abnormal_pituitary_gland0.54697162
70MP0002229_neurodegeneration0.53285681
71MP0009763_increased_sensitivity_to0.52494254
72MP0000716_abnormal_immune_system0.51923583
73MP0001501_abnormal_sleep_pattern0.51108190
74MP0001835_abnormal_antigen_presentation0.50224852
75MP0005164_abnormal_response_to0.48940120
76MP0000230_abnormal_systemic_arterial0.48203334
77MP0008877_abnormal_DNA_methylation0.47141295
78MP0008469_abnormal_protein_level0.46427834
79MP0003699_abnormal_female_reproductive0.46052494
80MP0003448_altered_tumor_morphology0.45604707
81MP0006072_abnormal_retinal_apoptosis0.45253394
82MP0003195_calcinosis0.43811218
83MP0005023_abnormal_wound_healing0.43786119
84MP0001845_abnormal_inflammatory_respons0.43255958
85MP0005379_endocrine/exocrine_gland_phen0.42816866
86MP0002160_abnormal_reproductive_system0.40037414
87MP0003866_abnormal_defecation0.39578517
88MP0000477_abnormal_intestine_morphology0.38889283
89MP0001986_abnormal_taste_sensitivity0.38127943
90MP0010329_abnormal_lipoprotein_level0.37613607
91MP0005376_homeostasis/metabolism_phenot0.37529440
92MP0005410_abnormal_fertilization0.37497814
93MP0003698_abnormal_male_reproductive0.37466402
94MP0003646_muscle_fatigue0.36431801
95MP0004085_abnormal_heartbeat0.35456738
96MP0001944_abnormal_pancreas_morphology0.35381867
97MP0002272_abnormal_nervous_system0.35173080
98MP0002429_abnormal_blood_cell0.34764296
99MP0003283_abnormal_digestive_organ0.34212721
100MP0005584_abnormal_enzyme/coenzyme_acti0.33727286

Predicted human phenotypes

RankGene SetZ-score
1Brushfield spots (HP:0001088)9.48338991
2Delayed closure of the anterior fontanelle (HP:0001476)7.82615981
3Flat occiput (HP:0005469)7.73092156
4Autoimmune thrombocytopenia (HP:0001973)5.79246984
5Asplenia (HP:0001746)5.50154608
6Nasal polyposis (HP:0100582)5.43913982
7Stomatitis (HP:0010280)5.32433117
8Chronic mucocutaneous candidiasis (HP:0002728)5.30457479
9Recurrent cutaneous fungal infections (HP:0011370)5.30457479
10Abnormality of B cell number (HP:0010975)5.28294530
11Epiphyseal stippling (HP:0010655)5.19426417
12Aplasia/Hypoplasia of the spleen (HP:0010451)5.17920984
13Primary adrenal insufficiency (HP:0008207)4.78120644
14Abnormality of the nasal mucosa (HP:0000433)4.50180468
15Aplastic anemia (HP:0001915)4.33817773
16Keratoconjunctivitis (HP:0001096)4.29793636
17Posterior embryotoxon (HP:0000627)4.25359138
18Female pseudohermaphroditism (HP:0010458)4.22637083
19Abnormality of the line of Schwalbe (HP:0008048)4.15475521
20Thickened nuchal skin fold (HP:0000474)4.03797070
21Recurrent fungal infections (HP:0002841)3.88876224
22Oral leukoplakia (HP:0002745)3.88625241
23Methylmalonic acidemia (HP:0002912)3.71801826
24Abnormal epiphyseal ossification (HP:0010656)3.71730812
25Abnormality of calcium-phosphate metabolism (HP:0100530)3.68741110
26Increased IgM level (HP:0003496)3.64784560
27Stomach cancer (HP:0012126)3.57283292
28Pustule (HP:0200039)3.55960491
29Delayed cranial suture closure (HP:0000270)3.44451189
30Autoimmune hemolytic anemia (HP:0001890)3.43209166
31Abnormality of homocysteine metabolism (HP:0010919)3.33692269
32Homocystinuria (HP:0002156)3.33692269
33Abnormal delayed hypersensitivity skin test (HP:0002963)3.28417707
34Abnormality of T cell physiology (HP:0011840)3.28348331
35Type I diabetes mellitus (HP:0100651)3.19960530
36Alopecia of scalp (HP:0002293)2.94218378
37Abnormality of methionine metabolism (HP:0010901)2.86884355
38Polydipsia (HP:0001959)2.79172899
39Abnormal drinking behavior (HP:0030082)2.79172899
40Underdeveloped supraorbital ridges (HP:0009891)2.76897468
41Chronic diarrhea (HP:0002028)2.76234469
42Hypercortisolism (HP:0001578)2.72651531
43Agammaglobulinemia (HP:0004432)2.72206212
44Methylmalonic aciduria (HP:0012120)2.68312716
45Abnormality of T cells (HP:0002843)2.53853817
46Respiratory distress (HP:0002098)2.50502925
47Abnormality of the vitamin B12 metabolism (HP:0004341)2.47575628
48Pyloric stenosis (HP:0002021)2.44519523
49Abnormality of aspartate family amino acid metabolism (HP:0010899)2.42290524
50Hypomagnesemia (HP:0002917)2.39024349
51Hypoparathyroidism (HP:0000829)2.37953019
52Megaloblastic anemia (HP:0001889)2.36512121
53Pancytopenia (HP:0001876)2.35003427
54Eosinophilia (HP:0001880)2.34964518
55Abnormality of vitamin B metabolism (HP:0004340)2.33025182
56Neutropenia (HP:0001875)2.32150277
57Tetany (HP:0001281)2.29077366
58Type II lissencephaly (HP:0007260)2.20755244
59Increased IgE level (HP:0003212)2.18651691
60Abnormality of cells of the lymphoid lineage (HP:0012140)2.18317993
61Spinal cord lesions (HP:0100561)2.18287846
62Syringomyelia (HP:0003396)2.18287846
63Conical tooth (HP:0000698)2.16929358
64Pendular nystagmus (HP:0012043)2.12289959
65Hypergammaglobulinemia (HP:0010702)2.09768349
66B lymphocytopenia (HP:0010976)2.09355080
67External ear malformation (HP:0008572)2.09149438
68Polyuria (HP:0000103)2.06524130
69Keratitis (HP:0000491)1.97701615
70Hypochromic anemia (HP:0001931)1.95576099
71Cholelithiasis (HP:0001081)1.94211190
72Cerebellar dysplasia (HP:0007033)1.92209880
73Abnormality of eosinophils (HP:0001879)1.91509345
74Short tibia (HP:0005736)1.91093513
75Abnormality of T cell number (HP:0011839)1.90776657
76Type 2 muscle fiber atrophy (HP:0003554)1.88353867
77Polyphagia (HP:0002591)1.85214409
78Recurrent skin infections (HP:0001581)1.83647335
79Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.83376689
80Glycosuria (HP:0003076)1.82378717
81Abnormality of urine glucose concentration (HP:0011016)1.82378717
82Premature birth (HP:0001622)1.80011294
83Hypoproteinemia (HP:0003075)1.79826873
84Abnormality of the pons (HP:0007361)1.78797175
85Pulmonary fibrosis (HP:0002206)1.77248379
86Aplasia/Hypoplasia of the tibia (HP:0005772)1.76723591
87Abnormal gallbladder morphology (HP:0012437)1.76605694
88Abnormality of magnesium homeostasis (HP:0004921)1.75512812
89Granulocytopenia (HP:0001913)1.73355507
90Abnormal urine output (HP:0012590)1.72190976
91Fibular aplasia (HP:0002990)1.69931082
92Thyroid-stimulating hormone excess (HP:0002925)1.68438509
93Hypoplasia of the pons (HP:0012110)1.67656045
94Increased CSF lactate (HP:0002490)1.67095198
95Hepatocellular necrosis (HP:0001404)1.67038723
96Cheilitis (HP:0100825)1.63456363
97Adrenal overactivity (HP:0002717)1.61459478
98Lymphopenia (HP:0001888)1.61109186
99Furrowed tongue (HP:0000221)1.61027420
100Congenital stationary night blindness (HP:0007642)1.58231247

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK9.99037803
2MAP3K138.14374142
3MAP3K143.99453327
4CAMKK13.66995734
5ITK3.20215290
6FGR2.89836816
7MAP3K121.77863496
8BMPR1B1.67249201
9TXK1.52778910
10MAP3K71.39802632
11IKBKB1.39429414
12PKN11.38703496
13ADRBK21.36779681
14CSK1.33669487
15MST41.22368336
16GRK11.09380276
17ZAK1.05649495
18FGFR11.03862497
19TAOK31.02657781
20TESK21.02006782
21GSK3A0.89551455
22MAP4K20.86399937
23TYK20.86089751
24BCKDK0.85067471
25NUAK10.84297468
26TIE10.83046406
27JAK10.80340075
28KDR0.77819192
29NEK90.77516223
30PBK0.75613164
31MAP4K10.74925867
32FRK0.74437675
33KIT0.72590148
34STK100.70869875
35VRK20.70637639
36PRKCQ0.69313528
37MAPK70.67309138
38PIK3CG0.64653051
39WNK40.62971751
40CHUK0.58530542
41EIF2AK30.57949529
42PLK40.54461775
43TSSK60.52724239
44TLK10.52306190
45WNK30.50709210
46TGFBR10.50106994
47INSRR0.49448850
48MUSK0.47916832
49SYK0.47390064
50ALK0.46956313
51CHEK20.46114858
52STK160.45796196
53BTK0.45763958
54LYN0.45581156
55PRKG20.40170514
56VRK10.39349327
57NME20.38886537
58STK390.38434963
59PLK10.37843014
60AURKA0.36963127
61CSNK1A10.36885290
62CSNK1G30.36739593
63PRKAA20.34881978
64CDK80.34663257
65BUB10.33914139
66LCK0.33415643
67TEC0.33206421
68CDK40.32597899
69CSNK1G10.32217692
70OBSCN0.31644952
71OXSR10.29931231
72LRRK20.29227428
73MAPK130.26796758
74RPS6KA40.26037089
75FYN0.26004096
76ABL10.25878942
77GRK70.25507408
78MAPK120.24801019
79CSNK1G20.24769126
80EIF2AK20.23821888
81CSNK1A1L0.23048170
82ADRBK10.22114461
83EIF2AK10.21584716
84IKBKE0.21164729
85RPS6KA50.20989111
86FLT30.20261844
87PINK10.18578416
88CCNB10.18381668
89CDC70.17863698
90PIM10.17470221
91PRKCA0.16528147
92PRKACA0.16299615
93PLK30.15777504
94BMPR20.13775552
95JAK20.13755119
96MAPK10.12720151
97MKNK10.12595533
98MAP3K110.12584590
99PHKG10.12440299
100PHKG20.12440299

Predicted pathways (KEGG)

RankGene SetZ-score
1Inflammatory bowel disease (IBD)_Homo sapiens_hsa053213.94378413
2Autoimmune thyroid disease_Homo sapiens_hsa053203.60338435
3Allograft rejection_Homo sapiens_hsa053303.59912283
4Graft-versus-host disease_Homo sapiens_hsa053323.24367610
5Ribosome_Homo sapiens_hsa030103.20949773
6Primary immunodeficiency_Homo sapiens_hsa053403.20102974
7Oxidative phosphorylation_Homo sapiens_hsa001902.98223143
8Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.66734541
9Type I diabetes mellitus_Homo sapiens_hsa049402.55927027
10RNA degradation_Homo sapiens_hsa030182.38145632
11Parkinsons disease_Homo sapiens_hsa050122.37175311
12RNA polymerase_Homo sapiens_hsa030202.21681950
13Peroxisome_Homo sapiens_hsa041462.17383571
14One carbon pool by folate_Homo sapiens_hsa006702.07636160
15Fanconi anemia pathway_Homo sapiens_hsa034602.06779603
16Intestinal immune network for IgA production_Homo sapiens_hsa046722.00537858
17Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.99909915
18Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.83064465
19Asthma_Homo sapiens_hsa053101.73609762
20Cardiac muscle contraction_Homo sapiens_hsa042601.68262481
21Huntingtons disease_Homo sapiens_hsa050161.65535445
22Alzheimers disease_Homo sapiens_hsa050101.65396414
23Vitamin digestion and absorption_Homo sapiens_hsa049771.49419644
24Proteasome_Homo sapiens_hsa030501.49080146
25Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.45292600
26Antigen processing and presentation_Homo sapiens_hsa046121.41630489
27RNA transport_Homo sapiens_hsa030131.41477593
28Sulfur metabolism_Homo sapiens_hsa009201.30923661
29B cell receptor signaling pathway_Homo sapiens_hsa046621.30545214
30Mineral absorption_Homo sapiens_hsa049781.27179608
31NOD-like receptor signaling pathway_Homo sapiens_hsa046211.24153868
32Retinol metabolism_Homo sapiens_hsa008301.16250160
33Pyrimidine metabolism_Homo sapiens_hsa002401.15894004
34Viral myocarditis_Homo sapiens_hsa054161.14336894
35Rheumatoid arthritis_Homo sapiens_hsa053231.09146679
36Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.09039718
37Purine metabolism_Homo sapiens_hsa002301.04716473
38T cell receptor signaling pathway_Homo sapiens_hsa046601.04691162
39Jak-STAT signaling pathway_Homo sapiens_hsa046301.03872522
40Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.97598493
41Arachidonic acid metabolism_Homo sapiens_hsa005900.96271011
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.90364327
43Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.85269490
44Dorso-ventral axis formation_Homo sapiens_hsa043200.84184449
45Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82043207
46Selenocompound metabolism_Homo sapiens_hsa004500.80805756
47Collecting duct acid secretion_Homo sapiens_hsa049660.79752632
48Legionellosis_Homo sapiens_hsa051340.77948115
49Epstein-Barr virus infection_Homo sapiens_hsa051690.77000504
50Malaria_Homo sapiens_hsa051440.76557356
51Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.75672916
52African trypanosomiasis_Homo sapiens_hsa051430.73714506
53Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.73126401
54Phototransduction_Homo sapiens_hsa047440.71427048
55Cysteine and methionine metabolism_Homo sapiens_hsa002700.71113392
56DNA replication_Homo sapiens_hsa030300.70725597
57Maturity onset diabetes of the young_Homo sapiens_hsa049500.70246761
58Systemic lupus erythematosus_Homo sapiens_hsa053220.70173157
59Herpes simplex infection_Homo sapiens_hsa051680.69458181
60RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.68369597
61Homologous recombination_Homo sapiens_hsa034400.68138702
62Sulfur relay system_Homo sapiens_hsa041220.67560051
63Tyrosine metabolism_Homo sapiens_hsa003500.65098828
64Linoleic acid metabolism_Homo sapiens_hsa005910.64633920
65Chemokine signaling pathway_Homo sapiens_hsa040620.64399619
66Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.62161343
67Caffeine metabolism_Homo sapiens_hsa002320.60388251
68Nitrogen metabolism_Homo sapiens_hsa009100.59245245
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.55650998
70Chemical carcinogenesis_Homo sapiens_hsa052040.54167569
71Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.51787689
72Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.49017978
73Regulation of autophagy_Homo sapiens_hsa041400.48400245
74NF-kappa B signaling pathway_Homo sapiens_hsa040640.47014140
75Protein export_Homo sapiens_hsa030600.47005438
76Spliceosome_Homo sapiens_hsa030400.42379629
77Mismatch repair_Homo sapiens_hsa034300.40682642
78Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.40155215
79Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.38518519
80Metabolic pathways_Homo sapiens_hsa011000.37305033
81Hematopoietic cell lineage_Homo sapiens_hsa046400.36052381
82Taste transduction_Homo sapiens_hsa047420.34434770
83Tryptophan metabolism_Homo sapiens_hsa003800.33518113
84TNF signaling pathway_Homo sapiens_hsa046680.32850145
85Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.31615211
86Dilated cardiomyopathy_Homo sapiens_hsa054140.31355260
87Complement and coagulation cascades_Homo sapiens_hsa046100.29346607
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.28801799
89Glycerolipid metabolism_Homo sapiens_hsa005610.28519850
90Olfactory transduction_Homo sapiens_hsa047400.27603085
91HTLV-I infection_Homo sapiens_hsa051660.24762993
92Tuberculosis_Homo sapiens_hsa051520.21675657
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.21257891
94Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.21085045
95alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20071487
96Circadian rhythm_Homo sapiens_hsa047100.19039735
97Leishmaniasis_Homo sapiens_hsa051400.18194452
98cAMP signaling pathway_Homo sapiens_hsa040240.18104800
99Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.17202761
100MAPK signaling pathway_Homo sapiens_hsa040100.16462429

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