

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 6.95644719 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.76994366 |
| 3 | viral transcription (GO:0019083) | 5.40692735 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 5.26013058 |
| 5 | translational termination (GO:0006415) | 5.13475740 |
| 6 | behavioral response to nicotine (GO:0035095) | 5.03152012 |
| 7 | DNA deamination (GO:0045006) | 4.94848628 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.66455271 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 4.62237501 |
| 10 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.60215944 |
| 11 | protein targeting to ER (GO:0045047) | 4.57244461 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.43564350 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.43564350 |
| 14 | translational elongation (GO:0006414) | 4.35693592 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.35608077 |
| 16 | ribosomal small subunit biogenesis (GO:0042274) | 4.34570895 |
| 17 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.32656220 |
| 18 | peptidyl-histidine modification (GO:0018202) | 4.27774168 |
| 19 | preassembly of GPI anchor in ER membrane (GO:0016254) | 4.20274034 |
| 20 | maturation of SSU-rRNA (GO:0030490) | 4.08236764 |
| 21 | piRNA metabolic process (GO:0034587) | 4.05361596 |
| 22 | translational initiation (GO:0006413) | 3.99892317 |
| 23 | intracellular protein transmembrane import (GO:0044743) | 3.94275694 |
| 24 | viral life cycle (GO:0019058) | 3.93961944 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.85046382 |
| 26 | cellular protein complex disassembly (GO:0043624) | 3.76045293 |
| 27 | translation (GO:0006412) | 3.75413420 |
| 28 | inner mitochondrial membrane organization (GO:0007007) | 3.72155216 |
| 29 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.68586442 |
| 30 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.68586442 |
| 31 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.68565334 |
| 32 | DNA methylation involved in gamete generation (GO:0043046) | 3.66965445 |
| 33 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.63615750 |
| 34 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.58681152 |
| 35 | male meiosis I (GO:0007141) | 3.48945055 |
| 36 | protein complex biogenesis (GO:0070271) | 3.41100141 |
| 37 | positive regulation of interleukin-17 production (GO:0032740) | 3.35342816 |
| 38 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.33020637 |
| 39 | positive regulation of protein homooligomerization (GO:0032464) | 3.32926247 |
| 40 | protein neddylation (GO:0045116) | 3.31610265 |
| 41 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.29829696 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.27698760 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.27698760 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.27698760 |
| 45 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.22221508 |
| 46 | fucose catabolic process (GO:0019317) | 3.18953253 |
| 47 | L-fucose metabolic process (GO:0042354) | 3.18953253 |
| 48 | L-fucose catabolic process (GO:0042355) | 3.18953253 |
| 49 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.15566843 |
| 50 | protein targeting to mitochondrion (GO:0006626) | 3.11488690 |
| 51 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.10494988 |
| 52 | protein complex disassembly (GO:0043241) | 3.06676907 |
| 53 | respiratory chain complex IV assembly (GO:0008535) | 3.04350496 |
| 54 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.03643527 |
| 55 | ribosomal large subunit biogenesis (GO:0042273) | 3.00874569 |
| 56 | GTP biosynthetic process (GO:0006183) | 2.99928466 |
| 57 | negative regulation of telomere maintenance (GO:0032205) | 2.97572256 |
| 58 | establishment of protein localization to mitochondrion (GO:0072655) | 2.97235141 |
| 59 | intracellular protein transmembrane transport (GO:0065002) | 2.95041807 |
| 60 | rRNA processing (GO:0006364) | 2.94235414 |
| 61 | positive regulation of isotype switching (GO:0045830) | 2.92844636 |
| 62 | protein targeting to membrane (GO:0006612) | 2.91757224 |
| 63 | cytidine metabolic process (GO:0046087) | 2.91389603 |
| 64 | cytidine catabolic process (GO:0006216) | 2.91389603 |
| 65 | cytidine deamination (GO:0009972) | 2.91389603 |
| 66 | response to xenobiotic stimulus (GO:0009410) | 2.88630967 |
| 67 | macromolecular complex disassembly (GO:0032984) | 2.88412493 |
| 68 | rRNA metabolic process (GO:0016072) | 2.86620770 |
| 69 | cellular component biogenesis (GO:0044085) | 2.85192642 |
| 70 | positive regulation of defense response to virus by host (GO:0002230) | 2.84679868 |
| 71 | GPI anchor biosynthetic process (GO:0006506) | 2.83962657 |
| 72 | electron transport chain (GO:0022900) | 2.83848157 |
| 73 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.81074038 |
| 74 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.77054206 |
| 75 | respiratory electron transport chain (GO:0022904) | 2.74614477 |
| 76 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.74290759 |
| 77 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.73051468 |
| 78 | protein localization to mitochondrion (GO:0070585) | 2.72337182 |
| 79 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.72034392 |
| 80 | GPI anchor metabolic process (GO:0006505) | 2.71566594 |
| 81 | meiosis I (GO:0007127) | 2.70877288 |
| 82 | ATP biosynthetic process (GO:0006754) | 2.69830755 |
| 83 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.69734705 |
| 84 | positive regulation of DNA recombination (GO:0045911) | 2.69505003 |
| 85 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.69075074 |
| 86 | interferon-gamma production (GO:0032609) | 2.68682542 |
| 87 | base-excision repair, AP site formation (GO:0006285) | 2.68137535 |
| 88 | tRNA processing (GO:0008033) | 2.66148079 |
| 89 | regulation of immunoglobulin secretion (GO:0051023) | 2.62054081 |
| 90 | pseudouridine synthesis (GO:0001522) | 2.60058789 |
| 91 | rRNA modification (GO:0000154) | 2.59981979 |
| 92 | positive regulation of cell fate commitment (GO:0010455) | 2.56701918 |
| 93 | mRNA catabolic process (GO:0006402) | 2.55805554 |
| 94 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 2.55373217 |
| 95 | protein transmembrane transport (GO:0071806) | 2.54925646 |
| 96 | cytochrome complex assembly (GO:0017004) | 2.52942591 |
| 97 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.52379329 |
| 98 | termination of RNA polymerase I transcription (GO:0006363) | 2.52294523 |
| 99 | ubiquinone biosynthetic process (GO:0006744) | 2.49644923 |
| 100 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.48772419 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.31927176 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.06034816 |
| 3 | VDR_22108803_ChIP-Seq_LS180_Human | 3.41772511 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.41522210 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.38173929 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.28797054 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.13772782 |
| 8 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.88434193 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.86566318 |
| 10 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.83366904 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.53563732 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.52956030 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.47607730 |
| 14 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.33877955 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.25563371 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.24545112 |
| 17 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.02694092 |
| 18 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.01206804 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.99930908 |
| 20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.96901107 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.96622740 |
| 22 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.93607541 |
| 23 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.83036532 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.77999897 |
| 25 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.76283484 |
| 26 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.75700945 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.73253893 |
| 28 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.68708987 |
| 29 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.68613934 |
| 30 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.66904692 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.62319781 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.60672569 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55070420 |
| 34 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.53742437 |
| 35 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.51173239 |
| 36 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.46924074 |
| 37 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46468203 |
| 38 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.44339394 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.42327894 |
| 40 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.41511796 |
| 41 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.37483591 |
| 42 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.36882447 |
| 43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.36559199 |
| 44 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.33453419 |
| 45 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.32692522 |
| 46 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27328559 |
| 47 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.24390780 |
| 48 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.24371027 |
| 49 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.22519444 |
| 50 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.20732473 |
| 51 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.20730788 |
| 52 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19469131 |
| 53 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19469131 |
| 54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.17867841 |
| 55 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.17306573 |
| 56 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14226072 |
| 57 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.13270085 |
| 58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.11740492 |
| 59 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.11669536 |
| 60 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10571612 |
| 61 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.10504161 |
| 62 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.09460407 |
| 63 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.09460407 |
| 64 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.08368065 |
| 65 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.08010758 |
| 66 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07782200 |
| 67 | AR_20517297_ChIP-Seq_VCAP_Human | 1.06743004 |
| 68 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.04898493 |
| 69 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.04794997 |
| 70 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.04768614 |
| 71 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04485205 |
| 72 | GATA3_26560356_Chip-Seq_TH2_Human | 1.03619805 |
| 73 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.03352596 |
| 74 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.01388999 |
| 75 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.01067604 |
| 76 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.01049625 |
| 77 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.00961335 |
| 78 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00518249 |
| 79 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.00028555 |
| 80 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.99369656 |
| 81 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.98831426 |
| 82 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.98526247 |
| 83 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98257979 |
| 84 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.97603789 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.97185042 |
| 86 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.96678647 |
| 87 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.95326312 |
| 88 | P300_19829295_ChIP-Seq_ESCs_Human | 0.94964219 |
| 89 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.94581451 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.93712906 |
| 91 | ERA_21632823_ChIP-Seq_H3396_Human | 0.92813508 |
| 92 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.90827143 |
| 93 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.89664776 |
| 94 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.87397699 |
| 95 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.87293024 |
| 96 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.86264441 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.86155846 |
| 98 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.86069109 |
| 99 | NCOR_22424771_ChIP-Seq_293T_Human | 0.85701864 |
| 100 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.84878655 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.95849924 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.86301780 |
| 3 | MP0003646_muscle_fatigue | 3.56855764 |
| 4 | MP0005670_abnormal_white_adipose | 2.75857422 |
| 5 | MP0008789_abnormal_olfactory_epithelium | 2.46929883 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.45119611 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.40760006 |
| 8 | MP0005671_abnormal_response_to | 2.36578856 |
| 9 | MP0002163_abnormal_gland_morphology | 2.34959966 |
| 10 | MP0002102_abnormal_ear_morphology | 2.29000397 |
| 11 | MP0003011_delayed_dark_adaptation | 2.12314923 |
| 12 | MP0001348_abnormal_lacrimal_gland | 2.04976365 |
| 13 | MP0002736_abnormal_nociception_after | 2.02502851 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 1.96680137 |
| 15 | MP0002138_abnormal_hepatobiliary_system | 1.89779730 |
| 16 | MP0001986_abnormal_taste_sensitivity | 1.88004650 |
| 17 | MP0001835_abnormal_antigen_presentation | 1.84815120 |
| 18 | MP0005394_taste/olfaction_phenotype | 1.82611002 |
| 19 | MP0005499_abnormal_olfactory_system | 1.82611002 |
| 20 | MP0003787_abnormal_imprinting | 1.78605807 |
| 21 | MP0003786_premature_aging | 1.77015856 |
| 22 | MP0004742_abnormal_vestibular_system | 1.73210877 |
| 23 | MP0008872_abnormal_physiological_respon | 1.70852109 |
| 24 | MP0003878_abnormal_ear_physiology | 1.69809802 |
| 25 | MP0005377_hearing/vestibular/ear_phenot | 1.69809802 |
| 26 | MP0002837_dystrophic_cardiac_calcinosis | 1.62974958 |
| 27 | MP0000685_abnormal_immune_system | 1.61031075 |
| 28 | MP0000015_abnormal_ear_pigmentation | 1.60319721 |
| 29 | MP0001790_abnormal_immune_system | 1.60069388 |
| 30 | MP0005387_immune_system_phenotype | 1.60069388 |
| 31 | MP0006072_abnormal_retinal_apoptosis | 1.59985714 |
| 32 | MP0005084_abnormal_gallbladder_morpholo | 1.59763598 |
| 33 | MP0005379_endocrine/exocrine_gland_phen | 1.53899546 |
| 34 | MP0001485_abnormal_pinna_reflex | 1.51079239 |
| 35 | MP0004142_abnormal_muscle_tone | 1.49023752 |
| 36 | MP0000372_irregular_coat_pigmentation | 1.47040704 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.44345927 |
| 38 | MP0005174_abnormal_tail_pigmentation | 1.42779809 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.42525672 |
| 40 | MP0004145_abnormal_muscle_electrophysio | 1.41495433 |
| 41 | MP0005645_abnormal_hypothalamus_physiol | 1.38329431 |
| 42 | MP0002272_abnormal_nervous_system | 1.37420043 |
| 43 | MP0001293_anophthalmia | 1.31197039 |
| 44 | MP0009333_abnormal_splenocyte_physiolog | 1.31126949 |
| 45 | MP0002876_abnormal_thyroid_physiology | 1.29794945 |
| 46 | MP0003136_yellow_coat_color | 1.24852787 |
| 47 | MP0001919_abnormal_reproductive_system | 1.23929709 |
| 48 | MP0008057_abnormal_DNA_replication | 1.23813713 |
| 49 | MP0001800_abnormal_humoral_immune | 1.23328790 |
| 50 | MP0003567_abnormal_fetal_cardiomyocyte | 1.23267228 |
| 51 | MP0001984_abnormal_olfaction | 1.22414295 |
| 52 | MP0009745_abnormal_behavioral_response | 1.20853677 |
| 53 | MP0004885_abnormal_endolymph | 1.17917404 |
| 54 | MP0005389_reproductive_system_phenotype | 1.16411757 |
| 55 | MP0001501_abnormal_sleep_pattern | 1.16010318 |
| 56 | MP0002095_abnormal_skin_pigmentation | 1.15717086 |
| 57 | MP0008875_abnormal_xenobiotic_pharmacok | 1.14375182 |
| 58 | MP0005167_abnormal_blood-brain_barrier | 1.12787165 |
| 59 | MP0003763_abnormal_thymus_physiology | 1.12641933 |
| 60 | MP0000631_abnormal_neuroendocrine_gland | 1.10255073 |
| 61 | MP0006035_abnormal_mitochondrial_morpho | 1.09536951 |
| 62 | MP0010030_abnormal_orbit_morphology | 1.02571981 |
| 63 | MP0005408_hypopigmentation | 1.01995863 |
| 64 | MP0002723_abnormal_immune_serum | 1.01225723 |
| 65 | MP0005253_abnormal_eye_physiology | 1.00784518 |
| 66 | MP0003959_abnormal_lean_body | 0.98784966 |
| 67 | MP0002148_abnormal_hypersensitivity_rea | 0.96773915 |
| 68 | MP0002160_abnormal_reproductive_system | 0.96673579 |
| 69 | MP0001905_abnormal_dopamine_level | 0.96149567 |
| 70 | MP0002938_white_spotting | 0.94668287 |
| 71 | MP0001440_abnormal_grooming_behavior | 0.93487933 |
| 72 | MP0001502_abnormal_circadian_rhythm | 0.91892998 |
| 73 | MP0002735_abnormal_chemical_nociception | 0.91391746 |
| 74 | MP0003121_genomic_imprinting | 0.91342458 |
| 75 | MP0008058_abnormal_DNA_repair | 0.90196827 |
| 76 | MP0000427_abnormal_hair_cycle | 0.89848346 |
| 77 | MP0002210_abnormal_sex_determination | 0.89228693 |
| 78 | MP0001853_heart_inflammation | 0.88421091 |
| 79 | MP0001529_abnormal_vocalization | 0.82893192 |
| 80 | MP0001663_abnormal_digestive_system | 0.81068331 |
| 81 | MP0003252_abnormal_bile_duct | 0.80990713 |
| 82 | MP0009046_muscle_twitch | 0.80706247 |
| 83 | MP0002006_tumorigenesis | 0.79755278 |
| 84 | MP0001486_abnormal_startle_reflex | 0.79377134 |
| 85 | MP0003122_maternal_imprinting | 0.79345949 |
| 86 | MP0003880_abnormal_central_pattern | 0.79122219 |
| 87 | MP0004036_abnormal_muscle_relaxation | 0.78329552 |
| 88 | MP0000049_abnormal_middle_ear | 0.77390566 |
| 89 | MP0003938_abnormal_ear_development | 0.76239371 |
| 90 | MP0005083_abnormal_biliary_tract | 0.75781212 |
| 91 | MP0001873_stomach_inflammation | 0.74187644 |
| 92 | MP0003879_abnormal_hair_cell | 0.72806108 |
| 93 | MP0003718_maternal_effect | 0.72485268 |
| 94 | MP0003186_abnormal_redox_activity | 0.71737154 |
| 95 | MP0005075_abnormal_melanosome_morpholog | 0.71590883 |
| 96 | MP0006276_abnormal_autonomic_nervous | 0.70565443 |
| 97 | MP0004133_heterotaxia | 0.70250018 |
| 98 | MP0003866_abnormal_defecation | 0.69852501 |
| 99 | MP0002452_abnormal_antigen_presenting | 0.69739093 |
| 100 | MP0005000_abnormal_immune_tolerance | 0.69032451 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Lipid accumulation in hepatocytes (HP:0006561) | 4.72539005 |
| 2 | Colon cancer (HP:0003003) | 3.54528343 |
| 3 | Panhypogammaglobulinemia (HP:0003139) | 3.47575920 |
| 4 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.46018149 |
| 5 | Pancreatic cysts (HP:0001737) | 3.30145163 |
| 6 | Methylmalonic aciduria (HP:0012120) | 3.30075014 |
| 7 | Stomatitis (HP:0010280) | 3.25366387 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.13525624 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.12892091 |
| 10 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.09843892 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 3.07130283 |
| 12 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.06656859 |
| 13 | Reticulocytopenia (HP:0001896) | 3.05517761 |
| 14 | Methylmalonic acidemia (HP:0002912) | 3.03502401 |
| 15 | IgG deficiency (HP:0004315) | 2.93371382 |
| 16 | Increased muscle lipid content (HP:0009058) | 2.92588484 |
| 17 | Increased CSF lactate (HP:0002490) | 2.92090034 |
| 18 | Bile duct proliferation (HP:0001408) | 2.86661809 |
| 19 | Abnormal biliary tract physiology (HP:0012439) | 2.86661809 |
| 20 | Renal Fanconi syndrome (HP:0001994) | 2.82054858 |
| 21 | Absent thumb (HP:0009777) | 2.80883822 |
| 22 | Progressive macrocephaly (HP:0004481) | 2.78908416 |
| 23 | Polydipsia (HP:0001959) | 2.77934238 |
| 24 | Abnormal drinking behavior (HP:0030082) | 2.77934238 |
| 25 | Acute encephalopathy (HP:0006846) | 2.76964002 |
| 26 | Increased IgM level (HP:0003496) | 2.76124098 |
| 27 | Abnormal number of erythroid precursors (HP:0012131) | 2.71662263 |
| 28 | Pancreatic fibrosis (HP:0100732) | 2.71020363 |
| 29 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.68560847 |
| 30 | Abnormality of midbrain morphology (HP:0002418) | 2.68393967 |
| 31 | Molar tooth sign on MRI (HP:0002419) | 2.68393967 |
| 32 | Hepatocellular necrosis (HP:0001404) | 2.66072401 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.59498371 |
| 34 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.57094427 |
| 35 | Enlarged kidneys (HP:0000105) | 2.56813122 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.52344577 |
| 37 | Adrenal hypoplasia (HP:0000835) | 2.50643904 |
| 38 | Asplenia (HP:0001746) | 2.48283527 |
| 39 | Abolished electroretinogram (ERG) (HP:0000550) | 2.43025494 |
| 40 | Hyperglycinemia (HP:0002154) | 2.41641167 |
| 41 | Macrocytic anemia (HP:0001972) | 2.40886918 |
| 42 | Type II lissencephaly (HP:0007260) | 2.35708500 |
| 43 | True hermaphroditism (HP:0010459) | 2.34994044 |
| 44 | Nephronophthisis (HP:0000090) | 2.33947249 |
| 45 | Respiratory difficulties (HP:0002880) | 2.33470764 |
| 46 | Agammaglobulinemia (HP:0004432) | 2.33432495 |
| 47 | Pendular nystagmus (HP:0012043) | 2.32314105 |
| 48 | Supernumerary spleens (HP:0009799) | 2.31725090 |
| 49 | Dicarboxylic aciduria (HP:0003215) | 2.30271867 |
| 50 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.30271867 |
| 51 | 3-Methylglutaconic aciduria (HP:0003535) | 2.29062000 |
| 52 | Hepatic necrosis (HP:0002605) | 2.26962289 |
| 53 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.26580112 |
| 54 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.26542948 |
| 55 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.26542948 |
| 56 | Recurrent cutaneous fungal infections (HP:0011370) | 2.25697322 |
| 57 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.25697322 |
| 58 | Optic disc pallor (HP:0000543) | 2.23677452 |
| 59 | Abnormality of T cell physiology (HP:0011840) | 2.23212609 |
| 60 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.22636150 |
| 61 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.22088103 |
| 62 | Hip dysplasia (HP:0001385) | 2.21136559 |
| 63 | Increased serum lactate (HP:0002151) | 2.18312230 |
| 64 | Polyuria (HP:0000103) | 2.16245235 |
| 65 | Respiratory failure (HP:0002878) | 2.09652222 |
| 66 | Abnormality of the labia minora (HP:0012880) | 2.08175623 |
| 67 | Lethargy (HP:0001254) | 2.07522159 |
| 68 | Exertional dyspnea (HP:0002875) | 2.07492735 |
| 69 | Lactic acidosis (HP:0003128) | 2.06394556 |
| 70 | Pallor (HP:0000980) | 2.05442657 |
| 71 | Rib fusion (HP:0000902) | 2.05332840 |
| 72 | Sclerocornea (HP:0000647) | 2.04386594 |
| 73 | Septo-optic dysplasia (HP:0100842) | 2.00376533 |
| 74 | Abnormal ciliary motility (HP:0012262) | 1.99560868 |
| 75 | Abnormality of the renal medulla (HP:0100957) | 1.97219107 |
| 76 | Increased intramyocellular lipid droplets (HP:0012240) | 1.93953359 |
| 77 | Mutism (HP:0002300) | 1.91689486 |
| 78 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91537856 |
| 79 | Progressive inability to walk (HP:0002505) | 1.90286898 |
| 80 | Chorioretinal atrophy (HP:0000533) | 1.90087781 |
| 81 | Glycosuria (HP:0003076) | 1.88818378 |
| 82 | Abnormality of urine glucose concentration (HP:0011016) | 1.88818378 |
| 83 | Concave nail (HP:0001598) | 1.88051333 |
| 84 | Chronic hepatic failure (HP:0100626) | 1.87922406 |
| 85 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.87769641 |
| 86 | Cerebral edema (HP:0002181) | 1.87308767 |
| 87 | Neutropenia (HP:0001875) | 1.86578020 |
| 88 | Cerebral hypomyelination (HP:0006808) | 1.82775868 |
| 89 | Nephrogenic diabetes insipidus (HP:0009806) | 1.82657342 |
| 90 | Hypoplasia of the radius (HP:0002984) | 1.82179122 |
| 91 | Abnormality of the renal cortex (HP:0011035) | 1.80945792 |
| 92 | Tubular atrophy (HP:0000092) | 1.80819636 |
| 93 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.80156905 |
| 94 | Cystic liver disease (HP:0006706) | 1.79567042 |
| 95 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.79068854 |
| 96 | Abnormality of glycine metabolism (HP:0010895) | 1.79068854 |
| 97 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.78347978 |
| 98 | Medial flaring of the eyebrow (HP:0010747) | 1.77933720 |
| 99 | Abnormality of renal resorption (HP:0011038) | 1.74880665 |
| 100 | Abnormality of vitamin B metabolism (HP:0004340) | 1.73781025 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.63858568 |
| 2 | ADRBK2 | 3.42144707 |
| 3 | FRK | 3.27379878 |
| 4 | ERN1 | 3.22728890 |
| 5 | WNK4 | 2.82156249 |
| 6 | TLK1 | 2.59142746 |
| 7 | DYRK2 | 2.36761137 |
| 8 | VRK2 | 2.32362487 |
| 9 | NEK1 | 2.09942482 |
| 10 | ZAK | 2.01003526 |
| 11 | BCKDK | 1.95787805 |
| 12 | PINK1 | 1.80664078 |
| 13 | STK39 | 1.76339817 |
| 14 | TSSK6 | 1.68365058 |
| 15 | MST4 | 1.67508410 |
| 16 | GRK1 | 1.65930421 |
| 17 | CSNK1G3 | 1.65039435 |
| 18 | CDK19 | 1.62430020 |
| 19 | CSNK1A1L | 1.58735655 |
| 20 | MAP2K2 | 1.57177457 |
| 21 | CSNK1G2 | 1.47010829 |
| 22 | CAMKK2 | 1.43646537 |
| 23 | IKBKE | 1.43153390 |
| 24 | CSNK1G1 | 1.42151443 |
| 25 | VRK1 | 1.40684970 |
| 26 | TEC | 1.37297064 |
| 27 | EIF2AK3 | 1.36201375 |
| 28 | SRPK1 | 1.29092098 |
| 29 | ADRBK1 | 1.23851471 |
| 30 | NUAK1 | 1.18094123 |
| 31 | BMPR1B | 1.16802826 |
| 32 | OXSR1 | 1.14516233 |
| 33 | NLK | 1.08654192 |
| 34 | PLK3 | 1.08033545 |
| 35 | IKBKB | 1.07034502 |
| 36 | ITK | 1.00729483 |
| 37 | FGFR2 | 0.99961230 |
| 38 | FES | 0.99165222 |
| 39 | TRIM28 | 0.98470649 |
| 40 | MAP4K2 | 0.97131087 |
| 41 | STK16 | 0.96123541 |
| 42 | PAK3 | 0.95287684 |
| 43 | RPS6KA5 | 0.94464668 |
| 44 | EIF2AK1 | 0.94318405 |
| 45 | IRAK2 | 0.93498081 |
| 46 | MKNK2 | 0.92530226 |
| 47 | MAP4K1 | 0.91115953 |
| 48 | DAPK2 | 0.84510072 |
| 49 | BUB1 | 0.80325260 |
| 50 | PDK2 | 0.80007395 |
| 51 | STK11 | 0.78608079 |
| 52 | TAF1 | 0.77957900 |
| 53 | PRKCG | 0.75893880 |
| 54 | PASK | 0.75245611 |
| 55 | ACVR1B | 0.73512496 |
| 56 | LRRK2 | 0.72602477 |
| 57 | INSRR | 0.71264782 |
| 58 | TYRO3 | 0.70525656 |
| 59 | PHKG1 | 0.68538847 |
| 60 | PHKG2 | 0.68538847 |
| 61 | MAP2K6 | 0.66892510 |
| 62 | CSNK2A2 | 0.66781681 |
| 63 | BTK | 0.62177326 |
| 64 | MKNK1 | 0.61725833 |
| 65 | CSNK1A1 | 0.60399239 |
| 66 | STK24 | 0.59998243 |
| 67 | PLK1 | 0.57467561 |
| 68 | MUSK | 0.57297316 |
| 69 | MARK3 | 0.57164424 |
| 70 | PRKCQ | 0.56635406 |
| 71 | DAPK3 | 0.54190336 |
| 72 | PIK3CA | 0.50524728 |
| 73 | TNIK | 0.49235986 |
| 74 | WNK1 | 0.48081394 |
| 75 | LYN | 0.47597415 |
| 76 | MAP3K8 | 0.47033942 |
| 77 | CSNK2A1 | 0.45547727 |
| 78 | MAPK13 | 0.45387517 |
| 79 | TGFBR1 | 0.45033117 |
| 80 | MAP2K1 | 0.45024588 |
| 81 | TAOK3 | 0.44605946 |
| 82 | GRK7 | 0.44000861 |
| 83 | JAK3 | 0.43172900 |
| 84 | DYRK1A | 0.43061692 |
| 85 | PRKCZ | 0.42862121 |
| 86 | PRKCI | 0.42721902 |
| 87 | SYK | 0.41406979 |
| 88 | CAMKK1 | 0.41150198 |
| 89 | PRKACA | 0.40606629 |
| 90 | CSNK1E | 0.40347319 |
| 91 | TIE1 | 0.40187595 |
| 92 | PRKCE | 0.40062386 |
| 93 | MAPKAPK5 | 0.39975437 |
| 94 | WEE1 | 0.39794667 |
| 95 | BRSK2 | 0.39770926 |
| 96 | IGF1R | 0.39167244 |
| 97 | PRKCD | 0.38783887 |
| 98 | EIF2AK2 | 0.38692944 |
| 99 | PLK2 | 0.38685291 |
| 100 | RPS6KA6 | 0.37972658 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.81593262 |
| 2 | Asthma_Homo sapiens_hsa05310 | 3.22205637 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.02465300 |
| 4 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.93824089 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.90465164 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.90110811 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.67206632 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.62005717 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.49997854 |
| 10 | Proteasome_Homo sapiens_hsa03050 | 2.42542419 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.29704469 |
| 12 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.20578575 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.20500015 |
| 14 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.20487292 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.91507979 |
| 16 | Homologous recombination_Homo sapiens_hsa03440 | 1.85759266 |
| 17 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.83448872 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.78822354 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.77397055 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.68778418 |
| 21 | Basal transcription factors_Homo sapiens_hsa03022 | 1.67296215 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.60320664 |
| 23 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.53047925 |
| 24 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.46646598 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.40255658 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.36214184 |
| 27 | Sulfur relay system_Homo sapiens_hsa04122 | 1.34811400 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.34797741 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.29169729 |
| 30 | Phototransduction_Homo sapiens_hsa04744 | 1.26083369 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.23989122 |
| 32 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.21479988 |
| 33 | Viral myocarditis_Homo sapiens_hsa05416 | 1.19472468 |
| 34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.10819719 |
| 35 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.09357052 |
| 36 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.06960189 |
| 37 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.05152040 |
| 38 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.03142636 |
| 39 | RNA transport_Homo sapiens_hsa03013 | 1.00813689 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.00485028 |
| 41 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.99029447 |
| 42 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.95179505 |
| 43 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.95126710 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.94951621 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.91083261 |
| 46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.90435571 |
| 47 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.88850890 |
| 48 | Base excision repair_Homo sapiens_hsa03410 | 0.88084654 |
| 49 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.88043766 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.87528269 |
| 51 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.87353702 |
| 52 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.86331950 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.81346516 |
| 54 | Mismatch repair_Homo sapiens_hsa03430 | 0.80245729 |
| 55 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76794501 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.73911397 |
| 57 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.72942206 |
| 58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.72812425 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.67731441 |
| 60 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.66096199 |
| 61 | Peroxisome_Homo sapiens_hsa04146 | 0.63898156 |
| 62 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.62436213 |
| 63 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61904539 |
| 64 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.59340992 |
| 65 | Purine metabolism_Homo sapiens_hsa00230 | 0.58414431 |
| 66 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.57245499 |
| 67 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.56081815 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.55003752 |
| 69 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.54977840 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54950064 |
| 71 | Nicotine addiction_Homo sapiens_hsa05033 | 0.53739718 |
| 72 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.51585216 |
| 73 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.49417663 |
| 74 | DNA replication_Homo sapiens_hsa03030 | 0.47980005 |
| 75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.47374071 |
| 76 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.45922328 |
| 77 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.40538087 |
| 78 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.39821312 |
| 79 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.39453313 |
| 80 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38927435 |
| 81 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.38450681 |
| 82 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37862353 |
| 83 | Retinol metabolism_Homo sapiens_hsa00830 | 0.37704698 |
| 84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.36616624 |
| 85 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.34950935 |
| 86 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.32891478 |
| 87 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.32820229 |
| 88 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32457133 |
| 89 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.30591436 |
| 90 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.30346340 |
| 91 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.29846123 |
| 92 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.29120652 |
| 93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27837802 |
| 94 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.27017563 |
| 95 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.26818401 |
| 96 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.23229652 |
| 97 | Measles_Homo sapiens_hsa05162 | 0.22680143 |
| 98 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.22435376 |
| 99 | GABAergic synapse_Homo sapiens_hsa04727 | 0.21357307 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.21242759 |

