

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of activation of Janus kinase activity (GO:0010533) | 8.27340643 |
| 2 | negative regulation of mast cell activation (GO:0033004) | 7.63274706 |
| 3 | negative regulation of phagocytosis (GO:0050765) | 7.33612475 |
| 4 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 7.28427086 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 6.05788854 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.05788854 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.89189621 |
| 8 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.76003126 |
| 9 | positive regulation of natural killer cell differentiation (GO:0032825) | 5.28152761 |
| 10 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 4.80478188 |
| 11 | peptidyl-histidine modification (GO:0018202) | 4.80291414 |
| 12 | negative regulation of B cell proliferation (GO:0030889) | 4.67657223 |
| 13 | maturation of 5.8S rRNA (GO:0000460) | 4.52811947 |
| 14 | negative regulation of alpha-beta T cell activation (GO:0046636) | 4.48459472 |
| 15 | autophagic vacuole fusion (GO:0000046) | 4.40694601 |
| 16 | proteasome assembly (GO:0043248) | 4.35788332 |
| 17 | positive regulation of interleukin-17 production (GO:0032740) | 4.12560627 |
| 18 | ribosomal large subunit biogenesis (GO:0042273) | 3.93438517 |
| 19 | regulation of chronic inflammatory response (GO:0002676) | 3.91179699 |
| 20 | ribosomal small subunit biogenesis (GO:0042274) | 3.89846454 |
| 21 | viral transcription (GO:0019083) | 3.82858782 |
| 22 | regulation of natural killer cell differentiation (GO:0032823) | 3.79335639 |
| 23 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.74431309 |
| 24 | translational termination (GO:0006415) | 3.72999022 |
| 25 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.65789460 |
| 26 | organelle membrane fusion (GO:0090174) | 3.65608003 |
| 27 | regulation of mast cell degranulation (GO:0043304) | 3.58169971 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.54978744 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.54978744 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.54978744 |
| 31 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.52251099 |
| 32 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 3.52023745 |
| 33 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.50362764 |
| 34 | DNA deamination (GO:0045006) | 3.44170249 |
| 35 | formation of translation preinitiation complex (GO:0001731) | 3.42797807 |
| 36 | cotranslational protein targeting to membrane (GO:0006613) | 3.40739174 |
| 37 | protein targeting to ER (GO:0045047) | 3.39432764 |
| 38 | protein localization to endoplasmic reticulum (GO:0070972) | 3.35298039 |
| 39 | regulation of cellular senescence (GO:2000772) | 3.33942080 |
| 40 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.33085150 |
| 41 | negative regulation of B cell activation (GO:0050869) | 3.32900127 |
| 42 | protein complex biogenesis (GO:0070271) | 3.32179388 |
| 43 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.31071642 |
| 44 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.26421782 |
| 45 | ATP biosynthetic process (GO:0006754) | 3.23719907 |
| 46 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.22246016 |
| 47 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 3.21880268 |
| 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.18918284 |
| 49 | translational initiation (GO:0006413) | 3.18568370 |
| 50 | ribosomal small subunit assembly (GO:0000028) | 3.17889574 |
| 51 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.15935624 |
| 52 | termination of RNA polymerase I transcription (GO:0006363) | 3.15662558 |
| 53 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.15252877 |
| 54 | translational elongation (GO:0006414) | 3.14661149 |
| 55 | negative regulation of leukocyte migration (GO:0002686) | 3.13609027 |
| 56 | negative regulation of macrophage differentiation (GO:0045650) | 3.11049011 |
| 57 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.10108064 |
| 58 | translation (GO:0006412) | 3.07330927 |
| 59 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.06993924 |
| 60 | electron transport chain (GO:0022900) | 3.05743092 |
| 61 | regulation of mitochondrial translation (GO:0070129) | 3.03665050 |
| 62 | positive regulation of interferon-gamma production (GO:0032729) | 3.02480473 |
| 63 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.01552898 |
| 64 | positive regulation of phosphatase activity (GO:0010922) | 3.01051860 |
| 65 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.00426797 |
| 66 | oxidative phosphorylation (GO:0006119) | 2.99929144 |
| 67 | respiratory electron transport chain (GO:0022904) | 2.99140876 |
| 68 | organic cation transport (GO:0015695) | 2.97992610 |
| 69 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.90940691 |
| 70 | positive regulation of interleukin-10 production (GO:0032733) | 2.90851498 |
| 71 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.90020097 |
| 72 | signal peptide processing (GO:0006465) | 2.89455008 |
| 73 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.88514386 |
| 74 | positive regulation of natural killer cell activation (GO:0032816) | 2.87212238 |
| 75 | maturation of SSU-rRNA (GO:0030490) | 2.84827758 |
| 76 | regulation of cellular respiration (GO:0043457) | 2.84694079 |
| 77 | regulation of B cell proliferation (GO:0030888) | 2.81836087 |
| 78 | viral mRNA export from host cell nucleus (GO:0046784) | 2.81346547 |
| 79 | positive regulation of prostaglandin secretion (GO:0032308) | 2.80454364 |
| 80 | regulation of mast cell activation (GO:0033003) | 2.79442167 |
| 81 | response to interferon-beta (GO:0035456) | 2.74934610 |
| 82 | cellular response to interferon-beta (GO:0035458) | 2.74508794 |
| 83 | viral life cycle (GO:0019058) | 2.73451034 |
| 84 | transcription initiation from RNA polymerase I promoter (GO:0006361) | 2.71832335 |
| 85 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.71625936 |
| 86 | cellular protein complex disassembly (GO:0043624) | 2.71601841 |
| 87 | kynurenine metabolic process (GO:0070189) | 2.70200098 |
| 88 | mast cell activation (GO:0045576) | 2.66234114 |
| 89 | termination of RNA polymerase III transcription (GO:0006386) | 2.65497320 |
| 90 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.65497320 |
| 91 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 2.64851942 |
| 92 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.61288598 |
| 93 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.59827028 |
| 94 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.58308774 |
| 95 | transcription from RNA polymerase I promoter (GO:0006360) | 2.58251777 |
| 96 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.56892912 |
| 97 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.56199064 |
| 98 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.56062399 |
| 99 | negative regulation of peptidyl-tyrosine phosphorylation (GO:0050732) | 2.52020222 |
| 100 | histone mRNA metabolic process (GO:0008334) | 2.51352906 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.74236057 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.42725044 |
| 3 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.20377531 |
| 4 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.13301559 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.75243403 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.72277633 |
| 7 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.32894749 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.91424160 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.88387387 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.87814992 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.80839716 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.73894529 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.72773342 |
| 14 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.72478033 |
| 15 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.62762855 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.46167690 |
| 17 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.32394507 |
| 18 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.29954181 |
| 19 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.27920593 |
| 20 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.04378748 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.00600623 |
| 22 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.99250146 |
| 23 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.95365867 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.94158296 |
| 25 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.87444015 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.79539637 |
| 27 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.79312969 |
| 28 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.77356343 |
| 29 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.74301581 |
| 30 | GATA3_26560356_Chip-Seq_TH2_Human | 1.73585573 |
| 31 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.70285599 |
| 32 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.62384269 |
| 33 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.58893593 |
| 34 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.58490771 |
| 35 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.55989038 |
| 36 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44494408 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.43766725 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.33258673 |
| 39 | VDR_22108803_ChIP-Seq_LS180_Human | 1.31657948 |
| 40 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.31621193 |
| 41 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.31012208 |
| 42 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.29526581 |
| 43 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.28889397 |
| 44 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.27704018 |
| 45 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26175750 |
| 46 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.26046172 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.24327063 |
| 48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.23233477 |
| 49 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22585766 |
| 50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.21872190 |
| 51 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.20191635 |
| 52 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.18917701 |
| 53 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.18704487 |
| 54 | EWS_26573619_Chip-Seq_HEK293_Human | 1.17034987 |
| 55 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.16584038 |
| 56 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.16584038 |
| 57 | MYB_26560356_Chip-Seq_TH2_Human | 1.15997765 |
| 58 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13297856 |
| 59 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.12786914 |
| 60 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.12131327 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11553680 |
| 62 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11553680 |
| 63 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.10873377 |
| 64 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10285423 |
| 65 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.05809929 |
| 66 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.05492180 |
| 67 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.03650210 |
| 68 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.01657888 |
| 69 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.01269294 |
| 70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.01232202 |
| 71 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.01159560 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.99843881 |
| 73 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.99489586 |
| 74 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.99300262 |
| 75 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98983313 |
| 76 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.98930746 |
| 77 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.98853450 |
| 78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.98609797 |
| 79 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.96613283 |
| 80 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 0.96416754 |
| 81 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.95945994 |
| 82 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.94328173 |
| 83 | FUS_26573619_Chip-Seq_HEK293_Human | 0.92848853 |
| 84 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.92318593 |
| 85 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.90828394 |
| 86 | NCOR_22424771_ChIP-Seq_293T_Human | 0.90316857 |
| 87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.90161789 |
| 88 | P300_27268052_Chip-Seq_Bcells_Human | 0.89789311 |
| 89 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.89756832 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.89592189 |
| 91 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.89182766 |
| 92 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.88650088 |
| 93 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88632812 |
| 94 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.88260560 |
| 95 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.87429746 |
| 96 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.87173873 |
| 97 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.86707094 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.86486984 |
| 99 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.86374790 |
| 100 | SOX2_21211035_ChIP-Seq_LN229_Human | 0.84237379 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003646_muscle_fatigue | 7.57705699 |
| 2 | MP0003806_abnormal_nucleotide_metabolis | 5.70026122 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.78895980 |
| 4 | MP0002138_abnormal_hepatobiliary_system | 2.53535817 |
| 5 | MP0004145_abnormal_muscle_electrophysio | 2.39413130 |
| 6 | MP0005451_abnormal_body_composition | 2.30033005 |
| 7 | MP0006036_abnormal_mitochondrial_physio | 2.23711300 |
| 8 | MP0001873_stomach_inflammation | 2.09289392 |
| 9 | MP0006082_CNS_inflammation | 1.97470120 |
| 10 | MP0003786_premature_aging | 1.96516014 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 1.90463855 |
| 12 | MP0001790_abnormal_immune_system | 1.82694181 |
| 13 | MP0005387_immune_system_phenotype | 1.82694181 |
| 14 | MP0006072_abnormal_retinal_apoptosis | 1.82079368 |
| 15 | MP0002166_altered_tumor_susceptibility | 1.81325908 |
| 16 | MP0002332_abnormal_exercise_endurance | 1.79226435 |
| 17 | MP0008872_abnormal_physiological_respon | 1.78558777 |
| 18 | MP0001919_abnormal_reproductive_system | 1.77839300 |
| 19 | MP0004036_abnormal_muscle_relaxation | 1.75576618 |
| 20 | MP0009379_abnormal_foot_pigmentation | 1.61554662 |
| 21 | MP0000015_abnormal_ear_pigmentation | 1.59028469 |
| 22 | MP0002452_abnormal_antigen_presenting | 1.58346504 |
| 23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.57633355 |
| 24 | MP0005671_abnormal_response_to | 1.55913733 |
| 25 | MP0001800_abnormal_humoral_immune | 1.55664046 |
| 26 | MP0008995_early_reproductive_senescence | 1.51384763 |
| 27 | MP0005266_abnormal_metabolism | 1.49810713 |
| 28 | MP0003195_calcinosis | 1.49465678 |
| 29 | MP0004142_abnormal_muscle_tone | 1.49257748 |
| 30 | MP0004742_abnormal_vestibular_system | 1.47301005 |
| 31 | MP0001348_abnormal_lacrimal_gland | 1.46569038 |
| 32 | MP0003763_abnormal_thymus_physiology | 1.42884589 |
| 33 | MP0010307_abnormal_tumor_latency | 1.40933422 |
| 34 | MP0009785_altered_susceptibility_to | 1.40224002 |
| 35 | MP0002006_tumorigenesis | 1.39995349 |
| 36 | MP0009764_decreased_sensitivity_to | 1.38328811 |
| 37 | MP0010368_abnormal_lymphatic_system | 1.36641876 |
| 38 | MP0005000_abnormal_immune_tolerance | 1.36020599 |
| 39 | MP0002139_abnormal_hepatobiliary_system | 1.34228016 |
| 40 | MP0003693_abnormal_embryo_hatching | 1.33979674 |
| 41 | MP0002837_dystrophic_cardiac_calcinosis | 1.33690793 |
| 42 | MP0005253_abnormal_eye_physiology | 1.31529496 |
| 43 | MP0005408_hypopigmentation | 1.30502193 |
| 44 | MP0001986_abnormal_taste_sensitivity | 1.29427283 |
| 45 | MP0002723_abnormal_immune_serum | 1.25114252 |
| 46 | MP0002420_abnormal_adaptive_immunity | 1.24776276 |
| 47 | MP0001819_abnormal_immune_cell | 1.22274639 |
| 48 | MP0005410_abnormal_fertilization | 1.21944012 |
| 49 | MP0003724_increased_susceptibility_to | 1.21543541 |
| 50 | MP0005389_reproductive_system_phenotype | 1.19151211 |
| 51 | MP0005174_abnormal_tail_pigmentation | 1.18979606 |
| 52 | MP0003880_abnormal_central_pattern | 1.18629530 |
| 53 | MP0000685_abnormal_immune_system | 1.15674041 |
| 54 | MP0005360_urolithiasis | 1.14104854 |
| 55 | MP0000343_altered_response_to | 1.13781524 |
| 56 | MP0002419_abnormal_innate_immunity | 1.09639382 |
| 57 | MP0005645_abnormal_hypothalamus_physiol | 1.07668217 |
| 58 | MP0005167_abnormal_blood-brain_barrier | 1.05741063 |
| 59 | MP0004381_abnormal_hair_follicle | 1.05164270 |
| 60 | MP0001968_abnormal_touch/_nociception | 1.04974634 |
| 61 | MP0005166_decreased_susceptibility_to | 1.04816000 |
| 62 | MP0005025_abnormal_response_to | 1.03432304 |
| 63 | MP0003186_abnormal_redox_activity | 1.03346161 |
| 64 | MP0001845_abnormal_inflammatory_respons | 1.03055595 |
| 65 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01794230 |
| 66 | MP0005636_abnormal_mineral_homeostasis | 1.00755669 |
| 67 | MP0003943_abnormal_hepatobiliary_system | 0.99129428 |
| 68 | MP0008775_abnormal_heart_ventricle | 0.98928844 |
| 69 | MP0002148_abnormal_hypersensitivity_rea | 0.97811365 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.97410896 |
| 71 | MP0002163_abnormal_gland_morphology | 0.95359340 |
| 72 | MP0002736_abnormal_nociception_after | 0.91552047 |
| 73 | MP0005646_abnormal_pituitary_gland | 0.91136441 |
| 74 | MP0005551_abnormal_eye_electrophysiolog | 0.89207876 |
| 75 | MP0003866_abnormal_defecation | 0.87933778 |
| 76 | MP0002876_abnormal_thyroid_physiology | 0.86027510 |
| 77 | MP0003303_peritoneal_inflammation | 0.85128511 |
| 78 | MP0010155_abnormal_intestine_physiology | 0.84102504 |
| 79 | MP0001663_abnormal_digestive_system | 0.83129218 |
| 80 | MP0006054_spinal_hemorrhage | 0.82311179 |
| 81 | MP0005464_abnormal_platelet_physiology | 0.81921387 |
| 82 | MP0009384_cardiac_valve_regurgitation | 0.81309308 |
| 83 | MP0008469_abnormal_protein_level | 0.79268676 |
| 84 | MP0001324_abnormal_eye_pigmentation | 0.79252501 |
| 85 | MP0005319_abnormal_enzyme/_coenzyme | 0.77784762 |
| 86 | MP0001501_abnormal_sleep_pattern | 0.77660588 |
| 87 | MP0003718_maternal_effect | 0.75891584 |
| 88 | MP0006035_abnormal_mitochondrial_morpho | 0.75351660 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.75338305 |
| 90 | MP0001502_abnormal_circadian_rhythm | 0.74499564 |
| 91 | MP0005332_abnormal_amino_acid | 0.74446311 |
| 92 | MP0009745_abnormal_behavioral_response | 0.72704633 |
| 93 | MP0002398_abnormal_bone_marrow | 0.70719031 |
| 94 | MP0003075_altered_response_to | 0.70704387 |
| 95 | MP0002429_abnormal_blood_cell | 0.70186238 |
| 96 | MP0000716_abnormal_immune_system | 0.70027163 |
| 97 | MP0008058_abnormal_DNA_repair | 0.69662608 |
| 98 | MP0000613_abnormal_salivary_gland | 0.68287557 |
| 99 | MP0005376_homeostasis/metabolism_phenot | 0.66951358 |
| 100 | MP0002090_abnormal_vision | 0.66919464 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 7.08838889 |
| 2 | Testicular atrophy (HP:0000029) | 5.51246370 |
| 3 | Microvesicular hepatic steatosis (HP:0001414) | 4.23300996 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.91497121 |
| 5 | Bile duct proliferation (HP:0001408) | 3.76114868 |
| 6 | Abnormal biliary tract physiology (HP:0012439) | 3.76114868 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.74276053 |
| 8 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.68702450 |
| 9 | Abnormality of B cell number (HP:0010975) | 3.65933122 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.59759241 |
| 11 | Increased CSF lactate (HP:0002490) | 3.48008308 |
| 12 | Methylmalonic acidemia (HP:0002912) | 3.47551773 |
| 13 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.46561313 |
| 14 | Lipid accumulation in hepatocytes (HP:0006561) | 3.44495900 |
| 15 | Progressive macrocephaly (HP:0004481) | 3.40637334 |
| 16 | Dyschromatopsia (HP:0007641) | 3.37621331 |
| 17 | B lymphocytopenia (HP:0010976) | 3.37106112 |
| 18 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.34483279 |
| 19 | Severe visual impairment (HP:0001141) | 3.32264236 |
| 20 | Acute encephalopathy (HP:0006846) | 3.20890913 |
| 21 | Pancreatic cysts (HP:0001737) | 3.12289146 |
| 22 | Methylmalonic aciduria (HP:0012120) | 3.02260860 |
| 23 | Renovascular hypertension (HP:0100817) | 3.02107695 |
| 24 | Congenital, generalized hypertrichosis (HP:0004540) | 3.01777228 |
| 25 | Dicarboxylic aciduria (HP:0003215) | 2.94122054 |
| 26 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.94122054 |
| 27 | Abnormal drinking behavior (HP:0030082) | 2.90543932 |
| 28 | Polydipsia (HP:0001959) | 2.90543932 |
| 29 | Chronic diarrhea (HP:0002028) | 2.90150165 |
| 30 | Exertional dyspnea (HP:0002875) | 2.88541320 |
| 31 | Increased serum lactate (HP:0002151) | 2.70856936 |
| 32 | Renal Fanconi syndrome (HP:0001994) | 2.70426568 |
| 33 | Ragged-red muscle fibers (HP:0003200) | 2.62797816 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.59880411 |
| 35 | Abnormality of midbrain morphology (HP:0002418) | 2.59880411 |
| 36 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.59119222 |
| 37 | Increased intramyocellular lipid droplets (HP:0012240) | 2.56199653 |
| 38 | Abnormality of the renal cortex (HP:0011035) | 2.54246573 |
| 39 | Respiratory difficulties (HP:0002880) | 2.53914596 |
| 40 | Tubulointerstitial nephritis (HP:0001970) | 2.52373401 |
| 41 | Optic disc pallor (HP:0000543) | 2.50922332 |
| 42 | Parakeratosis (HP:0001036) | 2.48637017 |
| 43 | Alveolar cell carcinoma (HP:0006519) | 2.41986806 |
| 44 | Attenuation of retinal blood vessels (HP:0007843) | 2.41122489 |
| 45 | Hypoproteinemia (HP:0003075) | 2.39832372 |
| 46 | Sensory axonal neuropathy (HP:0003390) | 2.39597515 |
| 47 | Hepatocellular necrosis (HP:0001404) | 2.38163855 |
| 48 | Abolished electroretinogram (ERG) (HP:0000550) | 2.38089150 |
| 49 | Macrocytic anemia (HP:0001972) | 2.37025440 |
| 50 | Cerebral edema (HP:0002181) | 2.30891574 |
| 51 | Paralysis (HP:0003470) | 2.28165702 |
| 52 | Elfin facies (HP:0004428) | 2.25580161 |
| 53 | Tubulointerstitial abnormality (HP:0001969) | 2.24640110 |
| 54 | Nephronophthisis (HP:0000090) | 2.20357530 |
| 55 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.18713012 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.18404751 |
| 57 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.17047951 |
| 58 | Hepatic necrosis (HP:0002605) | 2.14568660 |
| 59 | Lactic acidosis (HP:0003128) | 2.10586743 |
| 60 | Increased muscle lipid content (HP:0009058) | 2.10294564 |
| 61 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.07587298 |
| 62 | Renal cortical cysts (HP:0000803) | 2.06588020 |
| 63 | Polyuria (HP:0000103) | 2.06283401 |
| 64 | Abnormality of eosinophils (HP:0001879) | 2.02964768 |
| 65 | Chronic hepatic failure (HP:0100626) | 2.01869702 |
| 66 | Severe combined immunodeficiency (HP:0004430) | 2.01103791 |
| 67 | Abnormality of the diencephalon (HP:0010662) | 1.99366287 |
| 68 | Increased IgM level (HP:0003496) | 1.99355510 |
| 69 | Abnormality of vitamin B metabolism (HP:0004340) | 1.98913498 |
| 70 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.97837641 |
| 71 | Enlarged epiphyses (HP:0010580) | 1.97798509 |
| 72 | Myotonia (HP:0002486) | 1.97725640 |
| 73 | Abnormality of the prostate (HP:0008775) | 1.94327030 |
| 74 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.92963973 |
| 75 | Tubular atrophy (HP:0000092) | 1.91745428 |
| 76 | Median cleft lip (HP:0000161) | 1.91443614 |
| 77 | Exercise intolerance (HP:0003546) | 1.90420056 |
| 78 | Abnormality of vitamin metabolism (HP:0100508) | 1.88071495 |
| 79 | Megalencephaly (HP:0001355) | 1.87485278 |
| 80 | Conical tooth (HP:0000698) | 1.87080357 |
| 81 | Respiratory failure (HP:0002878) | 1.86070929 |
| 82 | Overriding aorta (HP:0002623) | 1.82836451 |
| 83 | Thyroiditis (HP:0100646) | 1.82374959 |
| 84 | Pancreatic fibrosis (HP:0100732) | 1.81824298 |
| 85 | Malnutrition (HP:0004395) | 1.81603448 |
| 86 | Tubulointerstitial fibrosis (HP:0005576) | 1.81410736 |
| 87 | Increased purine levels (HP:0004368) | 1.80681738 |
| 88 | Hyperuricemia (HP:0002149) | 1.80681738 |
| 89 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.80174195 |
| 90 | Progressive muscle weakness (HP:0003323) | 1.80133514 |
| 91 | Lethargy (HP:0001254) | 1.78707185 |
| 92 | Abnormality of renal resorption (HP:0011038) | 1.77131954 |
| 93 | Constricted visual fields (HP:0001133) | 1.75535806 |
| 94 | Eosinophilia (HP:0001880) | 1.73206910 |
| 95 | Megaloblastic anemia (HP:0001889) | 1.72578133 |
| 96 | Hyperacusis (HP:0010780) | 1.69924736 |
| 97 | Long nose (HP:0003189) | 1.69822869 |
| 98 | IgG deficiency (HP:0004315) | 1.66935313 |
| 99 | Abnormal urine output (HP:0012590) | 1.66416524 |
| 100 | Cleft eyelid (HP:0000625) | 1.66253875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | LIMK1 | 4.81922317 |
| 2 | EIF2AK3 | 4.21124724 |
| 3 | TIE1 | 4.02338924 |
| 4 | MAP4K1 | 3.71925082 |
| 5 | CDK8 | 3.34770026 |
| 6 | SCYL2 | 3.06980602 |
| 7 | EIF2AK1 | 2.73709622 |
| 8 | TXK | 2.61451880 |
| 9 | TLK1 | 2.44476483 |
| 10 | SRPK1 | 2.38943398 |
| 11 | CDC42BPA | 2.27826052 |
| 12 | KIT | 2.24101935 |
| 13 | CLK1 | 2.03278219 |
| 14 | ADRBK2 | 1.95882158 |
| 15 | ZAP70 | 1.92316242 |
| 16 | CAMKK2 | 1.79474281 |
| 17 | TRIM28 | 1.73001850 |
| 18 | KDR | 1.71650475 |
| 19 | NUAK1 | 1.69208842 |
| 20 | GRK1 | 1.67864168 |
| 21 | BRSK1 | 1.67047455 |
| 22 | TEC | 1.60980893 |
| 23 | MST4 | 1.49207259 |
| 24 | NME2 | 1.45192153 |
| 25 | ZAK | 1.36804430 |
| 26 | BMPR2 | 1.30945160 |
| 27 | SYK | 1.24117674 |
| 28 | BMPR1B | 1.17720381 |
| 29 | BLK | 1.14185480 |
| 30 | WNK4 | 1.12735067 |
| 31 | FRK | 1.09811160 |
| 32 | TGFBR1 | 1.09771703 |
| 33 | ACVR1B | 1.03229623 |
| 34 | LYN | 0.96774330 |
| 35 | EIF2AK2 | 0.95788194 |
| 36 | RPS6KA5 | 0.95587573 |
| 37 | ITK | 0.95494964 |
| 38 | JAK3 | 0.93021257 |
| 39 | DYRK2 | 0.90119235 |
| 40 | VRK2 | 0.89559764 |
| 41 | RIPK4 | 0.88742217 |
| 42 | BCKDK | 0.85058436 |
| 43 | FES | 0.82541654 |
| 44 | MAP3K11 | 0.81607209 |
| 45 | MYLK | 0.81480603 |
| 46 | IRAK4 | 0.80675429 |
| 47 | BTK | 0.78478415 |
| 48 | INSRR | 0.78190532 |
| 49 | TYK2 | 0.78003393 |
| 50 | GRK6 | 0.77385745 |
| 51 | CSNK1G3 | 0.76366139 |
| 52 | CSNK1A1L | 0.75871220 |
| 53 | ILK | 0.75658509 |
| 54 | PIK3CG | 0.73085380 |
| 55 | CSNK1G1 | 0.70409964 |
| 56 | MAPK11 | 0.65851279 |
| 57 | TNK2 | 0.63764685 |
| 58 | IKBKB | 0.60836517 |
| 59 | STK39 | 0.60242308 |
| 60 | RPS6KA4 | 0.56852673 |
| 61 | PAK1 | 0.56283953 |
| 62 | MELK | 0.56239554 |
| 63 | CSNK1G2 | 0.55960002 |
| 64 | BUB1 | 0.55567050 |
| 65 | JAK1 | 0.55190361 |
| 66 | CSNK2A2 | 0.53152134 |
| 67 | MAP4K2 | 0.51629543 |
| 68 | CAMKK1 | 0.49239010 |
| 69 | OXSR1 | 0.48953302 |
| 70 | TSSK6 | 0.48193445 |
| 71 | MAPKAPK2 | 0.47494603 |
| 72 | HCK | 0.46319447 |
| 73 | NEK1 | 0.46002291 |
| 74 | BRSK2 | 0.45467297 |
| 75 | PAK3 | 0.43031813 |
| 76 | PAK2 | 0.41887670 |
| 77 | STK16 | 0.41413276 |
| 78 | ATR | 0.40863063 |
| 79 | PRKCE | 0.40394126 |
| 80 | PNCK | 0.39673827 |
| 81 | CDC7 | 0.37676807 |
| 82 | MATK | 0.37096169 |
| 83 | CDK4 | 0.36879014 |
| 84 | CSNK2A1 | 0.35656394 |
| 85 | AKT3 | 0.33688196 |
| 86 | ROCK2 | 0.33621894 |
| 87 | PHKG2 | 0.32351227 |
| 88 | PHKG1 | 0.32351227 |
| 89 | OBSCN | 0.31375633 |
| 90 | CHEK1 | 0.31125912 |
| 91 | ROCK1 | 0.30478418 |
| 92 | PRKG1 | 0.30074889 |
| 93 | VRK1 | 0.29917203 |
| 94 | ERBB2 | 0.28962306 |
| 95 | RPS6KB2 | 0.27429850 |
| 96 | MAP2K6 | 0.27041563 |
| 97 | NLK | 0.26576622 |
| 98 | CSK | 0.26472434 |
| 99 | PBK | 0.26313711 |
| 100 | PRKAA2 | 0.25807879 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 3.99134679 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.64951184 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.59641536 |
| 4 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.50934740 |
| 5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.43982641 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 3.36071196 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.07696113 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.05064677 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.86190164 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.83503100 |
| 11 | Parkinsons disease_Homo sapiens_hsa05012 | 2.76960202 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.19659921 |
| 13 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.14336731 |
| 14 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.91184777 |
| 15 | Sulfur relay system_Homo sapiens_hsa04122 | 1.76405780 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.70741974 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.70498992 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 1.70072469 |
| 19 | Viral myocarditis_Homo sapiens_hsa05416 | 1.67046077 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.54488309 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.45110471 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.39410429 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.37256912 |
| 24 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.36142365 |
| 25 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.33402806 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.29323332 |
| 27 | Leishmaniasis_Homo sapiens_hsa05140 | 1.28148318 |
| 28 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.27058296 |
| 29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.26403023 |
| 30 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.22219772 |
| 31 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.21897016 |
| 32 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.17548854 |
| 33 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.16637009 |
| 34 | Homologous recombination_Homo sapiens_hsa03440 | 1.14775733 |
| 35 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.13447074 |
| 36 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.03043310 |
| 37 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.00803593 |
| 38 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.99840328 |
| 39 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.99834482 |
| 40 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.97487663 |
| 41 | DNA replication_Homo sapiens_hsa03030 | 0.96518609 |
| 42 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.95732779 |
| 43 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.95716717 |
| 44 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.95280471 |
| 45 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.93316096 |
| 46 | RNA transport_Homo sapiens_hsa03013 | 0.93017769 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.90937345 |
| 48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90239271 |
| 49 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.89356950 |
| 50 | Legionellosis_Homo sapiens_hsa05134 | 0.86939671 |
| 51 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.84402331 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.79333253 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.76079906 |
| 54 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.74652724 |
| 55 | Purine metabolism_Homo sapiens_hsa00230 | 0.67782472 |
| 56 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.67729608 |
| 57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.66759043 |
| 58 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.64371950 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63896959 |
| 60 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.63453102 |
| 61 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.62444060 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.61966675 |
| 63 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.59335513 |
| 64 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.55843333 |
| 65 | Mismatch repair_Homo sapiens_hsa03430 | 0.51274331 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.51214613 |
| 67 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.50699012 |
| 68 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.49058422 |
| 69 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46761511 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.46236357 |
| 71 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.44938544 |
| 72 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.44270881 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.44113177 |
| 74 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43894229 |
| 75 | Base excision repair_Homo sapiens_hsa03410 | 0.43522359 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42519213 |
| 77 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.40584861 |
| 78 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.39874274 |
| 79 | Basal transcription factors_Homo sapiens_hsa03022 | 0.39527735 |
| 80 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.38703696 |
| 81 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.37102827 |
| 82 | Measles_Homo sapiens_hsa05162 | 0.36693782 |
| 83 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.35807341 |
| 84 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.33824795 |
| 85 | Tuberculosis_Homo sapiens_hsa05152 | 0.33670751 |
| 86 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.32131068 |
| 87 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.31041641 |
| 88 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.30940515 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.30594913 |
| 90 | Phagosome_Homo sapiens_hsa04145 | 0.29439163 |
| 91 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.27818286 |
| 92 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.27718387 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.27090188 |
| 94 | Phototransduction_Homo sapiens_hsa04744 | 0.25870909 |
| 95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.24095242 |
| 96 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.23973017 |
| 97 | Peroxisome_Homo sapiens_hsa04146 | 0.23592502 |
| 98 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.22952373 |
| 99 | Influenza A_Homo sapiens_hsa05164 | 0.22826674 |
| 100 | Mineral absorption_Homo sapiens_hsa04978 | 0.19852513 |

