

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of natural killer cell differentiation (GO:0032825) | 7.15083600 |
| 2 | regulation of isotype switching to IgG isotypes (GO:0048302) | 7.04806921 |
| 3 | positive regulation of tyrosine phosphorylation of Stat1 protein (GO:0042511) | 6.87395834 |
| 4 | regulation of tyrosine phosphorylation of Stat1 protein (GO:0042510) | 5.92685527 |
| 5 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 5.77644933 |
| 6 | negative regulation of T-helper cell differentiation (GO:0045623) | 5.77644933 |
| 7 | positive regulation of interleukin-17 production (GO:0032740) | 5.50835798 |
| 8 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.47722633 |
| 9 | positive regulation of chemokine biosynthetic process (GO:0045080) | 5.43927993 |
| 10 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 5.43156783 |
| 11 | proteasome assembly (GO:0043248) | 5.37650995 |
| 12 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 5.15062980 |
| 13 | regulation of podosome assembly (GO:0071801) | 5.12664769 |
| 14 | regulation of MHC class II biosynthetic process (GO:0045346) | 5.10324539 |
| 15 | regulation of immunoglobulin secretion (GO:0051023) | 5.04342880 |
| 16 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 4.79204232 |
| 17 | regulation of natural killer cell differentiation (GO:0032823) | 4.78854772 |
| 18 | regulation of chronic inflammatory response (GO:0002676) | 4.78308812 |
| 19 | positive regulation of isotype switching (GO:0045830) | 4.64602473 |
| 20 | alpha-beta T cell activation involved in immune response (GO:0002287) | 4.44201077 |
| 21 | T cell differentiation involved in immune response (GO:0002292) | 4.44201077 |
| 22 | alpha-beta T cell differentiation involved in immune response (GO:0002293) | 4.44201077 |
| 23 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 4.40639210 |
| 24 | positive regulation of DNA recombination (GO:0045911) | 4.37738030 |
| 25 | pseudouridine synthesis (GO:0001522) | 4.37455098 |
| 26 | positive regulation of immunoglobulin production (GO:0002639) | 4.20088891 |
| 27 | regulation of chemokine biosynthetic process (GO:0045073) | 4.13224876 |
| 28 | regulation of immunoglobulin production (GO:0002637) | 4.12232109 |
| 29 | positive regulation of interleukin-10 production (GO:0032733) | 4.10073970 |
| 30 | viral mRNA export from host cell nucleus (GO:0046784) | 4.08475446 |
| 31 | DNA deamination (GO:0045006) | 4.06819159 |
| 32 | defense response to protozoan (GO:0042832) | 4.05586475 |
| 33 | regulation of interleukin-17 production (GO:0032660) | 3.84317380 |
| 34 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.71160583 |
| 35 | cellular response to interleukin-15 (GO:0071350) | 3.70813601 |
| 36 | regulation of isotype switching (GO:0045191) | 3.69075464 |
| 37 | regulation of proton transport (GO:0010155) | 3.66415636 |
| 38 | peptidyl-histidine modification (GO:0018202) | 3.61027112 |
| 39 | chaperone-mediated protein transport (GO:0072321) | 3.59703759 |
| 40 | response to protozoan (GO:0001562) | 3.48306505 |
| 41 | production of molecular mediator of immune response (GO:0002440) | 3.46903005 |
| 42 | ATP synthesis coupled proton transport (GO:0015986) | 3.40740774 |
| 43 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.40740774 |
| 44 | response to interleukin-15 (GO:0070672) | 3.38287971 |
| 45 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.35063672 |
| 46 | positive regulation of B cell proliferation (GO:0030890) | 3.32916859 |
| 47 | CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) | 3.32375355 |
| 48 | T-helper cell differentiation (GO:0042093) | 3.32375355 |
| 49 | termination of RNA polymerase III transcription (GO:0006386) | 3.28936374 |
| 50 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.28936374 |
| 51 | T cell lineage commitment (GO:0002360) | 3.26633308 |
| 52 | rRNA modification (GO:0000154) | 3.24632922 |
| 53 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.24066899 |
| 54 | mitochondrial RNA metabolic process (GO:0000959) | 3.23238501 |
| 55 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.21427123 |
| 56 | rRNA methylation (GO:0031167) | 3.19981687 |
| 57 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 3.18809878 |
| 58 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.16160999 |
| 59 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.16160999 |
| 60 | positive regulation of natural killer cell activation (GO:0032816) | 3.15998074 |
| 61 | positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) | 3.14448648 |
| 62 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.12874096 |
| 63 | GTP biosynthetic process (GO:0006183) | 3.11559529 |
| 64 | protein neddylation (GO:0045116) | 3.05889073 |
| 65 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.04889804 |
| 66 | isotype switching (GO:0045190) | 3.04889804 |
| 67 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.04889804 |
| 68 | retinal cone cell development (GO:0046549) | 3.02320777 |
| 69 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 3.00496040 |
| 70 | positive regulation of B cell mediated immunity (GO:0002714) | 3.00481667 |
| 71 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.00481667 |
| 72 | termination of RNA polymerase I transcription (GO:0006363) | 2.99550389 |
| 73 | necroptotic process (GO:0070266) | 2.98245426 |
| 74 | positive regulation of activated T cell proliferation (GO:0042104) | 2.95687135 |
| 75 | negative regulation of acute inflammatory response (GO:0002674) | 2.95328268 |
| 76 | positive regulation of JAK-STAT cascade (GO:0046427) | 2.94723442 |
| 77 | regulation of interleukin-10 production (GO:0032653) | 2.91812988 |
| 78 | regulation of vitamin metabolic process (GO:0030656) | 2.90426623 |
| 79 | negative regulation of T cell differentiation (GO:0045581) | 2.90332351 |
| 80 | mRNA cleavage (GO:0006379) | 2.89747363 |
| 81 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.88654058 |
| 82 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.88654058 |
| 83 | positive regulation of production of molecular mediator of immune response (GO:0002702) | 2.87297685 |
| 84 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.85743162 |
| 85 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.83148606 |
| 86 | L-fucose catabolic process (GO:0042355) | 2.82936796 |
| 87 | fucose catabolic process (GO:0019317) | 2.82936796 |
| 88 | L-fucose metabolic process (GO:0042354) | 2.82936796 |
| 89 | piRNA metabolic process (GO:0034587) | 2.81786887 |
| 90 | cytokine production involved in immune response (GO:0002367) | 2.80416004 |
| 91 | response to mercury ion (GO:0046689) | 2.79764133 |
| 92 | regulation of interleukin-13 production (GO:0032656) | 2.78846386 |
| 93 | positive regulation of cell killing (GO:0031343) | 2.78523286 |
| 94 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.78277910 |
| 95 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.78277910 |
| 96 | regulation of tyrosine phosphorylation of STAT protein (GO:0042509) | 2.78119821 |
| 97 | regulation of cell killing (GO:0031341) | 2.75824711 |
| 98 | regulation of memory T cell differentiation (GO:0043380) | 2.73872992 |
| 99 | positive regulation of osteoclast differentiation (GO:0045672) | 2.71978354 |
| 100 | regulation of T-helper cell differentiation (GO:0045622) | 2.70865746 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 5.36436731 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.39335158 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.36906837 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.04181285 |
| 5 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.34484139 |
| 6 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 3.28202082 |
| 7 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.25757449 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.15701997 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.76486765 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.71228512 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.65413921 |
| 12 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.57649727 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.54118426 |
| 14 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.48369309 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.40014938 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.13534412 |
| 17 | TP53_22573176_ChIP-Seq_HFKS_Human | 2.11048309 |
| 18 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.10545497 |
| 19 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.10052754 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96757539 |
| 21 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.94013282 |
| 22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.89681638 |
| 23 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.87350583 |
| 24 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.86962800 |
| 25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.86211569 |
| 26 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.84025424 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.80046380 |
| 28 | EWS_26573619_Chip-Seq_HEK293_Human | 1.78837532 |
| 29 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.68724713 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.61199138 |
| 31 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.54810741 |
| 32 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.53665932 |
| 33 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.53620733 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.50691145 |
| 35 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.49487941 |
| 36 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.44382600 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.41850895 |
| 38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.40940776 |
| 39 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.38535734 |
| 40 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.37843316 |
| 41 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.37147158 |
| 42 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.37099800 |
| 43 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.36740576 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.36216003 |
| 45 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.36192363 |
| 46 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.31797070 |
| 47 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.29688403 |
| 48 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.29120442 |
| 49 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26583574 |
| 50 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.25948359 |
| 51 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.23008846 |
| 52 | GATA3_26560356_Chip-Seq_TH2_Human | 1.22542215 |
| 53 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.22458326 |
| 54 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.20060852 |
| 55 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.19821319 |
| 56 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.19753600 |
| 57 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.16835826 |
| 58 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.16780034 |
| 59 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.16608392 |
| 60 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.15052861 |
| 61 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.13240215 |
| 62 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.12426132 |
| 63 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.12327792 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.09181290 |
| 65 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.08678965 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.08464551 |
| 67 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.07941765 |
| 68 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.05691702 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.05016738 |
| 70 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 1.04584090 |
| 71 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.02485026 |
| 72 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01099752 |
| 73 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.00736291 |
| 74 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.99670808 |
| 75 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98663392 |
| 76 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.98080342 |
| 77 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.97819236 |
| 78 | GATA1_22025678_ChIP-Seq_K562_Human | 0.95526835 |
| 79 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92087190 |
| 80 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.91988029 |
| 81 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.91988029 |
| 82 | AR_20517297_ChIP-Seq_VCAP_Human | 0.90078814 |
| 83 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.89555454 |
| 84 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.89236751 |
| 85 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.88679132 |
| 86 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.88098125 |
| 87 | NFYB_21822215_ChIP-Seq_K562_Human | 0.87493301 |
| 88 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.87201385 |
| 89 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87101826 |
| 90 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.86326775 |
| 91 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.85787352 |
| 92 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.85591421 |
| 93 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85318366 |
| 94 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.85120487 |
| 95 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.84858080 |
| 96 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.84619758 |
| 97 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.84367257 |
| 98 | FUS_26573619_Chip-Seq_HEK293_Human | 0.84126062 |
| 99 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.83826143 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.83103587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005360_urolithiasis | 9.15886094 |
| 2 | MP0001873_stomach_inflammation | 5.25433953 |
| 3 | MP0001835_abnormal_antigen_presentation | 4.07391875 |
| 4 | MP0001348_abnormal_lacrimal_gland | 4.02554973 |
| 5 | MP0005671_abnormal_response_to | 3.29505361 |
| 6 | MP0002138_abnormal_hepatobiliary_system | 3.23533712 |
| 7 | MP0008875_abnormal_xenobiotic_pharmacok | 2.56977446 |
| 8 | MP0005645_abnormal_hypothalamus_physiol | 2.50948273 |
| 9 | MP0009333_abnormal_splenocyte_physiolog | 2.46010767 |
| 10 | MP0005387_immune_system_phenotype | 2.19639856 |
| 11 | MP0001790_abnormal_immune_system | 2.19639856 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.18527938 |
| 13 | MP0002102_abnormal_ear_morphology | 2.14636699 |
| 14 | MP0008872_abnormal_physiological_respon | 2.12313642 |
| 15 | MP0000685_abnormal_immune_system | 2.11229014 |
| 16 | MP0005310_abnormal_salivary_gland | 2.03467712 |
| 17 | MP0000538_abnormal_urinary_bladder | 2.01673800 |
| 18 | MP0008057_abnormal_DNA_replication | 1.97934419 |
| 19 | MP0006082_CNS_inflammation | 1.92475889 |
| 20 | MP0004742_abnormal_vestibular_system | 1.70576207 |
| 21 | MP0000569_abnormal_digit_pigmentation | 1.63099806 |
| 22 | MP0003646_muscle_fatigue | 1.57691475 |
| 23 | MP0005167_abnormal_blood-brain_barrier | 1.56842749 |
| 24 | MP0003786_premature_aging | 1.55462552 |
| 25 | MP0001984_abnormal_olfaction | 1.53831447 |
| 26 | MP0004145_abnormal_muscle_electrophysio | 1.52303494 |
| 27 | MP0004381_abnormal_hair_follicle | 1.49569153 |
| 28 | MP0004043_abnormal_pH_regulation | 1.47351283 |
| 29 | MP0002234_abnormal_pharynx_morphology | 1.46692636 |
| 30 | MP0005000_abnormal_immune_tolerance | 1.43135568 |
| 31 | MP0001800_abnormal_humoral_immune | 1.33231104 |
| 32 | MP0009785_altered_susceptibility_to | 1.31578504 |
| 33 | MP0002166_altered_tumor_susceptibility | 1.28185454 |
| 34 | MP0008995_early_reproductive_senescence | 1.24852890 |
| 35 | MP0001968_abnormal_touch/_nociception | 1.20730620 |
| 36 | MP0004957_abnormal_blastocyst_morpholog | 1.19542248 |
| 37 | MP0008058_abnormal_DNA_repair | 1.18387679 |
| 38 | MP0003252_abnormal_bile_duct | 1.15192524 |
| 39 | MP0002405_respiratory_system_inflammati | 1.14521928 |
| 40 | MP0003718_maternal_effect | 1.10262588 |
| 41 | MP0005408_hypopigmentation | 1.09770169 |
| 42 | MP0004885_abnormal_endolymph | 1.08426580 |
| 43 | MP0001919_abnormal_reproductive_system | 1.08087131 |
| 44 | MP0005085_abnormal_gallbladder_physiolo | 1.07839466 |
| 45 | MP0005410_abnormal_fertilization | 1.04336351 |
| 46 | MP0002148_abnormal_hypersensitivity_rea | 1.02385975 |
| 47 | MP0002006_tumorigenesis | 0.99947079 |
| 48 | MP0001958_emphysema | 0.99903953 |
| 49 | MP0003186_abnormal_redox_activity | 0.99768129 |
| 50 | MP0003195_calcinosis | 0.98652864 |
| 51 | MP0006292_abnormal_olfactory_placode | 0.98284536 |
| 52 | MP0008789_abnormal_olfactory_epithelium | 0.95309481 |
| 53 | MP0003763_abnormal_thymus_physiology | 0.95082518 |
| 54 | MP0002736_abnormal_nociception_after | 0.94255767 |
| 55 | MP0010155_abnormal_intestine_physiology | 0.88878063 |
| 56 | MP0004142_abnormal_muscle_tone | 0.88308796 |
| 57 | MP0005075_abnormal_melanosome_morpholog | 0.86836981 |
| 58 | MP0002210_abnormal_sex_determination | 0.86094597 |
| 59 | MP0005332_abnormal_amino_acid | 0.85191893 |
| 60 | MP0001663_abnormal_digestive_system | 0.85117885 |
| 61 | MP0003950_abnormal_plasma_membrane | 0.84946348 |
| 62 | MP0000689_abnormal_spleen_morphology | 0.81644897 |
| 63 | MP0002254_reproductive_system_inflammat | 0.81257271 |
| 64 | MP0004782_abnormal_surfactant_physiolog | 0.78941852 |
| 65 | MP0001756_abnormal_urination | 0.77168992 |
| 66 | MP0006036_abnormal_mitochondrial_physio | 0.77017006 |
| 67 | MP0002420_abnormal_adaptive_immunity | 0.76913240 |
| 68 | MP0009745_abnormal_behavioral_response | 0.75544708 |
| 69 | MP0002723_abnormal_immune_serum | 0.73567780 |
| 70 | MP0001501_abnormal_sleep_pattern | 0.73362883 |
| 71 | MP0003045_fibrosis | 0.72758905 |
| 72 | MP0005389_reproductive_system_phenotype | 0.72688791 |
| 73 | MP0003693_abnormal_embryo_hatching | 0.72295305 |
| 74 | MP0001905_abnormal_dopamine_level | 0.71672835 |
| 75 | MP0002396_abnormal_hematopoietic_system | 0.71527592 |
| 76 | MP0001502_abnormal_circadian_rhythm | 0.71417763 |
| 77 | MP0002163_abnormal_gland_morphology | 0.70789664 |
| 78 | MP0005646_abnormal_pituitary_gland | 0.70435691 |
| 79 | MP0005025_abnormal_response_to | 0.70338661 |
| 80 | MP0002452_abnormal_antigen_presenting | 0.69659842 |
| 81 | MP0002277_abnormal_respiratory_mucosa | 0.69069948 |
| 82 | MP0008961_abnormal_basal_metabolism | 0.68872236 |
| 83 | MP0001929_abnormal_gametogenesis | 0.68705817 |
| 84 | MP0005084_abnormal_gallbladder_morpholo | 0.68132764 |
| 85 | MP0001881_abnormal_mammary_gland | 0.67894314 |
| 86 | MP0001819_abnormal_immune_cell | 0.67832435 |
| 87 | MP0010368_abnormal_lymphatic_system | 0.65332400 |
| 88 | MP0001661_extended_life_span | 0.64842129 |
| 89 | MP0001485_abnormal_pinna_reflex | 0.64614196 |
| 90 | MP0005083_abnormal_biliary_tract | 0.64317003 |
| 91 | MP0002722_abnormal_immune_system | 0.64014577 |
| 92 | MP0000703_abnormal_thymus_morphology | 0.62171981 |
| 93 | MP0001119_abnormal_female_reproductive | 0.62085661 |
| 94 | MP0002733_abnormal_thermal_nociception | 0.61860104 |
| 95 | MP0005501_abnormal_skin_physiology | 0.60361049 |
| 96 | MP0001845_abnormal_inflammatory_respons | 0.57192281 |
| 97 | MP0000653_abnormal_sex_gland | 0.56544494 |
| 98 | MP0005166_decreased_susceptibility_to | 0.56110689 |
| 99 | MP0005551_abnormal_eye_electrophysiolog | 0.55562001 |
| 100 | MP0001145_abnormal_male_reproductive | 0.52021124 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomatitis (HP:0010280) | 5.56995566 |
| 2 | Tongue fasciculations (HP:0001308) | 5.22750517 |
| 3 | Abnormality of the pons (HP:0007361) | 5.00391180 |
| 4 | Muscle fibrillation (HP:0010546) | 4.81356848 |
| 5 | Chronic diarrhea (HP:0002028) | 4.57971620 |
| 6 | Severe muscular hypotonia (HP:0006829) | 4.05738675 |
| 7 | Hypoplasia of the pons (HP:0012110) | 3.99378122 |
| 8 | Fatigue (HP:0012378) | 3.95241756 |
| 9 | Generalized aminoaciduria (HP:0002909) | 3.56947604 |
| 10 | Large for gestational age (HP:0001520) | 3.42442496 |
| 11 | Nephronophthisis (HP:0000090) | 3.32137704 |
| 12 | Reduced antithrombin III activity (HP:0001976) | 3.19887609 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.18016128 |
| 14 | IgG deficiency (HP:0004315) | 3.14146914 |
| 15 | Renal cortical cysts (HP:0000803) | 3.12864967 |
| 16 | Increased IgM level (HP:0003496) | 3.01493028 |
| 17 | Abnormality of T cell physiology (HP:0011840) | 2.90010507 |
| 18 | Abnormal spermatogenesis (HP:0008669) | 2.89024048 |
| 19 | Type I transferrin isoform profile (HP:0003642) | 2.86860388 |
| 20 | Congenital stationary night blindness (HP:0007642) | 2.83431929 |
| 21 | Increased CSF lactate (HP:0002490) | 2.81320434 |
| 22 | IgA deficiency (HP:0002720) | 2.75789884 |
| 23 | Abnormality of alanine metabolism (HP:0010916) | 2.71284693 |
| 24 | Hyperalaninemia (HP:0003348) | 2.71284693 |
| 25 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.71284693 |
| 26 | Abnormality of the renal medulla (HP:0100957) | 2.68912715 |
| 27 | Abnormality of T cells (HP:0002843) | 2.65961822 |
| 28 | Azoospermia (HP:0000027) | 2.54939322 |
| 29 | Duplicated collecting system (HP:0000081) | 2.50699181 |
| 30 | Abnormality of the renal cortex (HP:0011035) | 2.47860806 |
| 31 | Cerebellar dysplasia (HP:0007033) | 2.47756950 |
| 32 | Increased serum lactate (HP:0002151) | 2.46729633 |
| 33 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.39942975 |
| 34 | Hypomagnesemia (HP:0002917) | 2.34535353 |
| 35 | Mutism (HP:0002300) | 2.34408227 |
| 36 | Oral leukoplakia (HP:0002745) | 2.31005232 |
| 37 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.30785464 |
| 38 | Renal tubular acidosis (HP:0001947) | 2.30505376 |
| 39 | Acute necrotizing encephalopathy (HP:0006965) | 2.30346981 |
| 40 | Type II lissencephaly (HP:0007260) | 2.26838107 |
| 41 | Abnormality of the renal collecting system (HP:0004742) | 2.26784466 |
| 42 | Hepatic necrosis (HP:0002605) | 2.25355705 |
| 43 | Increased serum pyruvate (HP:0003542) | 2.22801869 |
| 44 | Abnormality of incisor morphology (HP:0011063) | 2.22043038 |
| 45 | Thyroiditis (HP:0100646) | 2.21712612 |
| 46 | Limb dystonia (HP:0002451) | 2.21289789 |
| 47 | CNS hypomyelination (HP:0003429) | 2.20023931 |
| 48 | Abnormality of vitamin B metabolism (HP:0004340) | 2.19546422 |
| 49 | Arthropathy (HP:0003040) | 2.17524367 |
| 50 | Proximal tubulopathy (HP:0000114) | 2.16476740 |
| 51 | Abnormal protein glycosylation (HP:0012346) | 2.13251734 |
| 52 | Abnormal glycosylation (HP:0012345) | 2.13251734 |
| 53 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.13251734 |
| 54 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.13251734 |
| 55 | Severe combined immunodeficiency (HP:0004430) | 2.10445156 |
| 56 | Acute encephalopathy (HP:0006846) | 2.09136769 |
| 57 | Gonadotropin excess (HP:0000837) | 2.07643271 |
| 58 | Multiple enchondromatosis (HP:0005701) | 2.07320711 |
| 59 | Delayed CNS myelination (HP:0002188) | 2.06358799 |
| 60 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.06219674 |
| 61 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.06219674 |
| 62 | Medial flaring of the eyebrow (HP:0010747) | 2.05556808 |
| 63 | Abnormality of magnesium homeostasis (HP:0004921) | 2.05444443 |
| 64 | Abnormal number of erythroid precursors (HP:0012131) | 2.03683877 |
| 65 | Molar tooth sign on MRI (HP:0002419) | 2.03460877 |
| 66 | Abnormality of midbrain morphology (HP:0002418) | 2.03460877 |
| 67 | Homocystinuria (HP:0002156) | 2.02820564 |
| 68 | Abnormality of homocysteine metabolism (HP:0010919) | 2.02820564 |
| 69 | Lethargy (HP:0001254) | 2.00333856 |
| 70 | Pulmonary infiltrates (HP:0002113) | 1.96935821 |
| 71 | Mitochondrial inheritance (HP:0001427) | 1.96606059 |
| 72 | Lactic acidosis (HP:0003128) | 1.95063874 |
| 73 | Attenuation of retinal blood vessels (HP:0007843) | 1.93255006 |
| 74 | Abnormal cartilage morphology (HP:0002763) | 1.92439997 |
| 75 | Nausea (HP:0002018) | 1.91838054 |
| 76 | Adactyly (HP:0009776) | 1.90455586 |
| 77 | Abnormality of T cell number (HP:0011839) | 1.90381998 |
| 78 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.89014224 |
| 79 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88667863 |
| 80 | Joint swelling (HP:0001386) | 1.87809664 |
| 81 | Pancreatic cysts (HP:0001737) | 1.85753027 |
| 82 | Carpal bone hypoplasia (HP:0001498) | 1.85432443 |
| 83 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.84866911 |
| 84 | Absent epiphyses (HP:0010577) | 1.81963774 |
| 85 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.81963774 |
| 86 | T lymphocytopenia (HP:0005403) | 1.81926795 |
| 87 | Renal tubular dysfunction (HP:0000124) | 1.81794261 |
| 88 | Cleft eyelid (HP:0000625) | 1.81420844 |
| 89 | Hypoglycemic coma (HP:0001325) | 1.81056859 |
| 90 | Dyskinesia (HP:0100660) | 1.80435855 |
| 91 | Abnormality of the ileum (HP:0001549) | 1.78760059 |
| 92 | Progressive macrocephaly (HP:0004481) | 1.77311446 |
| 93 | Pachygyria (HP:0001302) | 1.75037556 |
| 94 | Wrist flexion contracture (HP:0001239) | 1.75009241 |
| 95 | Meckel diverticulum (HP:0002245) | 1.74161778 |
| 96 | Abnormality of the intrinsic pathway (HP:0010989) | 1.73509889 |
| 97 | Fibular aplasia (HP:0002990) | 1.73371538 |
| 98 | Exertional dyspnea (HP:0002875) | 1.73341877 |
| 99 | Flat capital femoral epiphysis (HP:0003370) | 1.71500395 |
| 100 | Abnormality of the preputium (HP:0100587) | 1.70328159 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BMPR1B | 4.34511429 |
| 2 | TSSK6 | 3.57653344 |
| 3 | EIF2AK1 | 3.37537129 |
| 4 | PKN2 | 3.26676742 |
| 5 | EIF2AK3 | 3.26538286 |
| 6 | PBK | 3.19632921 |
| 7 | NME1 | 2.84554500 |
| 8 | CLK1 | 2.81781064 |
| 9 | BCKDK | 2.75994079 |
| 10 | ACVR1B | 2.56874755 |
| 11 | FLT3 | 2.52235830 |
| 12 | TGFBR1 | 2.47254798 |
| 13 | ADRBK2 | 2.34222297 |
| 14 | CDK8 | 2.14900410 |
| 15 | TLK1 | 2.13706622 |
| 16 | TXK | 2.10146723 |
| 17 | PAK6 | 1.75622697 |
| 18 | MST4 | 1.74687232 |
| 19 | TAOK3 | 1.63852701 |
| 20 | NLK | 1.63043517 |
| 21 | ZAK | 1.59547048 |
| 22 | WNK4 | 1.53477374 |
| 23 | MKNK2 | 1.52298419 |
| 24 | GRK1 | 1.45279627 |
| 25 | SRPK1 | 1.42222411 |
| 26 | FRK | 1.34849750 |
| 27 | CCNB1 | 1.33409880 |
| 28 | VRK2 | 1.29319366 |
| 29 | VRK1 | 1.27273075 |
| 30 | FGFR1 | 1.21825009 |
| 31 | PHKG1 | 1.19122043 |
| 32 | PHKG2 | 1.19122043 |
| 33 | IKBKB | 1.14613789 |
| 34 | MAP2K6 | 1.14056652 |
| 35 | EIF2AK2 | 1.13745003 |
| 36 | PLK3 | 1.04890160 |
| 37 | PAK3 | 1.02883416 |
| 38 | ITK | 0.98404698 |
| 39 | IRAK1 | 0.92913166 |
| 40 | ADRBK1 | 0.88309894 |
| 41 | BMPR2 | 0.87889707 |
| 42 | MAP3K14 | 0.83756263 |
| 43 | BRD4 | 0.83658914 |
| 44 | CSNK1G1 | 0.82518169 |
| 45 | IRAK2 | 0.81764948 |
| 46 | MKNK1 | 0.80052220 |
| 47 | STK4 | 0.79959332 |
| 48 | MARK3 | 0.78972480 |
| 49 | TNK2 | 0.73753889 |
| 50 | STK39 | 0.71516122 |
| 51 | LIMK1 | 0.66639594 |
| 52 | JAK1 | 0.66048566 |
| 53 | TIE1 | 0.62969568 |
| 54 | BUB1 | 0.62472277 |
| 55 | DYRK2 | 0.61362697 |
| 56 | ERBB3 | 0.61150980 |
| 57 | PINK1 | 0.59009885 |
| 58 | KSR1 | 0.59008374 |
| 59 | GRK7 | 0.57071678 |
| 60 | AKT3 | 0.54060028 |
| 61 | NUAK1 | 0.52718066 |
| 62 | OXSR1 | 0.49961270 |
| 63 | JAK3 | 0.47725157 |
| 64 | NEK1 | 0.46595490 |
| 65 | WNK3 | 0.46466095 |
| 66 | PDK2 | 0.45767578 |
| 67 | CSNK1G3 | 0.44837894 |
| 68 | CHUK | 0.44698837 |
| 69 | IKBKE | 0.44478193 |
| 70 | CSNK1A1L | 0.42699342 |
| 71 | CDK7 | 0.41788826 |
| 72 | TRIM28 | 0.41557192 |
| 73 | RPS6KA5 | 0.41227582 |
| 74 | PLK1 | 0.41085383 |
| 75 | PRKCQ | 0.40840927 |
| 76 | TESK1 | 0.39834068 |
| 77 | MAPKAPK3 | 0.39749821 |
| 78 | PRKCI | 0.38923641 |
| 79 | DAPK2 | 0.37671617 |
| 80 | PTK6 | 0.36730711 |
| 81 | EPHA4 | 0.36559669 |
| 82 | RPS6KA1 | 0.35984387 |
| 83 | PIM1 | 0.34950165 |
| 84 | FER | 0.34058891 |
| 85 | INSRR | 0.31922834 |
| 86 | CDK9 | 0.30724529 |
| 87 | JAK2 | 0.30722621 |
| 88 | CHEK1 | 0.30335142 |
| 89 | MAPK13 | 0.29985920 |
| 90 | ATM | 0.28737158 |
| 91 | TYK2 | 0.27672212 |
| 92 | PIM2 | 0.27121521 |
| 93 | PKN1 | 0.26096244 |
| 94 | CSNK2A2 | 0.24042746 |
| 95 | RAF1 | 0.24007521 |
| 96 | PRKAA2 | 0.23363065 |
| 97 | WNK1 | 0.22990287 |
| 98 | CSNK1E | 0.22927309 |
| 99 | CSNK2A1 | 0.22055411 |
| 100 | CDK4 | 0.19443209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 3.98844754 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.94126048 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.68824315 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.11659006 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.98939319 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.80923548 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.78652288 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.68237830 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.65865503 |
| 10 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.32844961 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.18297296 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.17216114 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.12256966 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.98188699 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.96434246 |
| 16 | Parkinsons disease_Homo sapiens_hsa05012 | 1.89964325 |
| 17 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.75408588 |
| 18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.74615318 |
| 19 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.61042737 |
| 20 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.60875954 |
| 21 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.55287916 |
| 22 | RNA transport_Homo sapiens_hsa03013 | 1.41920204 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37303867 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.30763289 |
| 25 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.29709912 |
| 26 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.28416754 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25651561 |
| 28 | Basal transcription factors_Homo sapiens_hsa03022 | 1.24190532 |
| 29 | RNA degradation_Homo sapiens_hsa03018 | 1.24140936 |
| 30 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19284808 |
| 31 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.15334070 |
| 32 | Huntingtons disease_Homo sapiens_hsa05016 | 1.13939224 |
| 33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.13929490 |
| 34 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.12036907 |
| 35 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.11596465 |
| 36 | Ribosome_Homo sapiens_hsa03010 | 1.08833033 |
| 37 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.07198376 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.06505813 |
| 39 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.06337242 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.01841098 |
| 41 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.01118448 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.00054613 |
| 43 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.98337964 |
| 44 | Spliceosome_Homo sapiens_hsa03040 | 0.97559329 |
| 45 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.96838470 |
| 46 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.92555413 |
| 47 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89777942 |
| 48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.83366225 |
| 49 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82696557 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.81786451 |
| 51 | Mismatch repair_Homo sapiens_hsa03430 | 0.81018022 |
| 52 | Mineral absorption_Homo sapiens_hsa04978 | 0.80055997 |
| 53 | Alzheimers disease_Homo sapiens_hsa05010 | 0.79849917 |
| 54 | Phototransduction_Homo sapiens_hsa04744 | 0.78610487 |
| 55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.75934188 |
| 56 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.75288717 |
| 57 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.72318700 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.71823960 |
| 59 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.70626894 |
| 60 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.69318040 |
| 61 | Measles_Homo sapiens_hsa05162 | 0.69097790 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.66551480 |
| 63 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.64707558 |
| 64 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64037381 |
| 65 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.63732753 |
| 66 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.61507214 |
| 67 | Malaria_Homo sapiens_hsa05144 | 0.59920987 |
| 68 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.59508983 |
| 69 | Taste transduction_Homo sapiens_hsa04742 | 0.58103172 |
| 70 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.56135385 |
| 71 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.55908109 |
| 72 | DNA replication_Homo sapiens_hsa03030 | 0.55853002 |
| 73 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55470398 |
| 74 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.53886238 |
| 75 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.52864664 |
| 76 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.50559546 |
| 77 | Olfactory transduction_Homo sapiens_hsa04740 | 0.48809796 |
| 78 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.48218466 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.48130696 |
| 80 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.45771384 |
| 81 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.42066259 |
| 82 | Base excision repair_Homo sapiens_hsa03410 | 0.39184923 |
| 83 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37539542 |
| 84 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.36971987 |
| 85 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.35490149 |
| 86 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.35204757 |
| 87 | Legionellosis_Homo sapiens_hsa05134 | 0.32391132 |
| 88 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.31555156 |
| 89 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31301459 |
| 90 | Retinol metabolism_Homo sapiens_hsa00830 | 0.29530777 |
| 91 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.29096354 |
| 92 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.29061310 |
| 93 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.28508882 |
| 94 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.27710440 |
| 95 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.27147722 |
| 96 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.26302228 |
| 97 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.24764702 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.21924610 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.21732891 |
| 100 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.21526074 |

