

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 8.02952332 |
| 2 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 7.04272422 |
| 3 | regulation of immunoglobulin secretion (GO:0051023) | 6.42832024 |
| 4 | regulation of regulatory T cell differentiation (GO:0045589) | 5.93569654 |
| 5 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.80936287 |
| 6 | chaperone-mediated protein transport (GO:0072321) | 5.52131470 |
| 7 | negative regulation of B cell apoptotic process (GO:0002903) | 5.33638759 |
| 8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.14250540 |
| 9 | positive regulation of isotype switching (GO:0045830) | 5.03934495 |
| 10 | peptidyl-histidine modification (GO:0018202) | 5.00786947 |
| 11 | GTP biosynthetic process (GO:0006183) | 4.85399699 |
| 12 | proteasome assembly (GO:0043248) | 4.72052903 |
| 13 | positive regulation of interleukin-17 production (GO:0032740) | 4.68987223 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 4.68564732 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.68564732 |
| 16 | rRNA modification (GO:0000154) | 4.64995354 |
| 17 | ribosomal small subunit assembly (GO:0000028) | 4.59967603 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.52820208 |
| 19 | pseudouridine synthesis (GO:0001522) | 4.50263169 |
| 20 | DNA deamination (GO:0045006) | 4.48156590 |
| 21 | positive regulation of DNA recombination (GO:0045911) | 4.40680405 |
| 22 | regulation of chronic inflammatory response (GO:0002676) | 4.28510317 |
| 23 | UTP biosynthetic process (GO:0006228) | 4.26504224 |
| 24 | ribosomal small subunit biogenesis (GO:0042274) | 4.15430019 |
| 25 | protein targeting to mitochondrion (GO:0006626) | 4.08804858 |
| 26 | translation (GO:0006412) | 3.87836176 |
| 27 | positive regulation of B cell mediated immunity (GO:0002714) | 3.82492936 |
| 28 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.82492936 |
| 29 | protein localization to mitochondrion (GO:0070585) | 3.79665613 |
| 30 | viral transcription (GO:0019083) | 3.79068732 |
| 31 | protein complex biogenesis (GO:0070271) | 3.74089296 |
| 32 | UTP metabolic process (GO:0046051) | 3.72710935 |
| 33 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.71697940 |
| 34 | termination of RNA polymerase III transcription (GO:0006386) | 3.71697940 |
| 35 | establishment of protein localization to mitochondrion (GO:0072655) | 3.71031372 |
| 36 | cotranslational protein targeting to membrane (GO:0006613) | 3.66855523 |
| 37 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.66590529 |
| 38 | cullin deneddylation (GO:0010388) | 3.65080973 |
| 39 | protein deneddylation (GO:0000338) | 3.62851530 |
| 40 | rRNA methylation (GO:0031167) | 3.62707642 |
| 41 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.61823545 |
| 42 | protein targeting to ER (GO:0045047) | 3.61372112 |
| 43 | translational termination (GO:0006415) | 3.59924522 |
| 44 | ribosome biogenesis (GO:0042254) | 3.56805887 |
| 45 | maturation of 5.8S rRNA (GO:0000460) | 3.55158458 |
| 46 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.50419729 |
| 47 | NADH dehydrogenase complex assembly (GO:0010257) | 3.50419729 |
| 48 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.50419729 |
| 49 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.49371778 |
| 50 | rRNA processing (GO:0006364) | 3.48011684 |
| 51 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.46616401 |
| 52 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.46485937 |
| 53 | respiratory chain complex IV assembly (GO:0008535) | 3.45373437 |
| 54 | regulation of B cell apoptotic process (GO:0002902) | 3.45308549 |
| 55 | response to pheromone (GO:0019236) | 3.45026700 |
| 56 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.43341464 |
| 57 | protein localization to endoplasmic reticulum (GO:0070972) | 3.41089889 |
| 58 | ribosome assembly (GO:0042255) | 3.39870783 |
| 59 | CTP metabolic process (GO:0046036) | 3.39772475 |
| 60 | CTP biosynthetic process (GO:0006241) | 3.39772475 |
| 61 | positive regulation of immunoglobulin production (GO:0002639) | 3.39746513 |
| 62 | translational elongation (GO:0006414) | 3.36482255 |
| 63 | rRNA metabolic process (GO:0016072) | 3.33034901 |
| 64 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.31854780 |
| 65 | cellular component biogenesis (GO:0044085) | 3.31109254 |
| 66 | regulation of immune response to tumor cell (GO:0002837) | 3.28455414 |
| 67 | regulation of response to tumor cell (GO:0002834) | 3.28455414 |
| 68 | positive regulation of response to tumor cell (GO:0002836) | 3.28455414 |
| 69 | positive regulation of immune response to tumor cell (GO:0002839) | 3.28455414 |
| 70 | respiratory electron transport chain (GO:0022904) | 3.20953519 |
| 71 | electron transport chain (GO:0022900) | 3.16741150 |
| 72 | translational initiation (GO:0006413) | 3.16625867 |
| 73 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.13356683 |
| 74 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.11886622 |
| 75 | maturation of SSU-rRNA (GO:0030490) | 3.11311063 |
| 76 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.10004050 |
| 77 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.09451608 |
| 78 | positive regulation of activated T cell proliferation (GO:0042104) | 3.07296380 |
| 79 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.05327256 |
| 80 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 3.04957767 |
| 81 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.04305254 |
| 82 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.04305254 |
| 83 | DNA damage response, detection of DNA damage (GO:0042769) | 3.03956556 |
| 84 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.02291045 |
| 85 | interferon-gamma production (GO:0032609) | 3.00156496 |
| 86 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.99631275 |
| 87 | tRNA processing (GO:0008033) | 2.99466099 |
| 88 | cytochrome complex assembly (GO:0017004) | 2.99199340 |
| 89 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.97878759 |
| 90 | ncRNA 3-end processing (GO:0043628) | 2.97291515 |
| 91 | protein neddylation (GO:0045116) | 2.96230926 |
| 92 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.95806184 |
| 93 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.95233920 |
| 94 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.95233920 |
| 95 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.95233920 |
| 96 | intracellular protein transmembrane import (GO:0044743) | 2.95210524 |
| 97 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.94212577 |
| 98 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.94212577 |
| 99 | embryonic hemopoiesis (GO:0035162) | 2.93702736 |
| 100 | viral life cycle (GO:0019058) | 2.92092891 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.30969800 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 5.03175405 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.90622687 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 4.34939219 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 4.29104011 |
| 6 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.90464987 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.40524192 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.37428116 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.86873675 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.72159145 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.72091013 |
| 12 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.62929369 |
| 13 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.61211914 |
| 14 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.58989572 |
| 15 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.57097786 |
| 16 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.38077636 |
| 17 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.35700258 |
| 18 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.34734903 |
| 19 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.32006840 |
| 20 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.13509550 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 2.13359871 |
| 22 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.13330012 |
| 23 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.09730670 |
| 24 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.07873561 |
| 25 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.04496924 |
| 26 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03517147 |
| 27 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90697074 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.89030447 |
| 29 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.88116646 |
| 30 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.78021453 |
| 31 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.72167001 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.71819787 |
| 33 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.63631813 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.59468517 |
| 35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57642246 |
| 36 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.56848743 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.51534176 |
| 38 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.48810060 |
| 39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47750824 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.47237996 |
| 41 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.46843709 |
| 42 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.43068991 |
| 43 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.36188178 |
| 44 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.35530990 |
| 45 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.33186207 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.30642642 |
| 47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.30586894 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27038081 |
| 49 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.26438849 |
| 50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25482363 |
| 51 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.21895963 |
| 52 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.20939725 |
| 53 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.20864976 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.18468284 |
| 55 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.18113228 |
| 56 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.17216963 |
| 57 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.12918606 |
| 58 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.10066176 |
| 59 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.09834190 |
| 60 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.08987913 |
| 61 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.07436804 |
| 62 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.06176075 |
| 63 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.06051496 |
| 64 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04851740 |
| 65 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.04536742 |
| 66 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.03810600 |
| 67 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.02728043 |
| 68 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.00652417 |
| 69 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.99902211 |
| 70 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.99853781 |
| 71 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.99826998 |
| 72 | NCOR_22424771_ChIP-Seq_293T_Human | 0.99224280 |
| 73 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.98817370 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.95511002 |
| 75 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95134243 |
| 76 | GATA3_26560356_Chip-Seq_TH2_Human | 0.94875490 |
| 77 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.94621280 |
| 78 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.94308869 |
| 79 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.93778097 |
| 80 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.93778097 |
| 81 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.93197935 |
| 82 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.93172331 |
| 83 | AR_20517297_ChIP-Seq_VCAP_Human | 0.92243313 |
| 84 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.91578250 |
| 85 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.90167529 |
| 86 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.89585498 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.89585498 |
| 88 | FUS_26573619_Chip-Seq_HEK293_Human | 0.89454193 |
| 89 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.89033426 |
| 90 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.88920059 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.88462811 |
| 92 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.87242335 |
| 93 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.86937501 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.86709319 |
| 95 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.86289619 |
| 96 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.85184615 |
| 97 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.85141040 |
| 98 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.84648056 |
| 99 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.83539323 |
| 100 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.82908257 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002163_abnormal_gland_morphology | 4.90748311 |
| 2 | MP0003136_yellow_coat_color | 4.13340204 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.75665793 |
| 4 | MP0000372_irregular_coat_pigmentation | 3.60058242 |
| 5 | MP0005379_endocrine/exocrine_gland_phen | 3.22152087 |
| 6 | MP0001348_abnormal_lacrimal_gland | 2.76977523 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.71408848 |
| 8 | MP0002277_abnormal_respiratory_mucosa | 2.68942084 |
| 9 | MP0006292_abnormal_olfactory_placode | 2.59976676 |
| 10 | MP0001853_heart_inflammation | 2.56165276 |
| 11 | MP0000685_abnormal_immune_system | 2.41757826 |
| 12 | MP0002102_abnormal_ear_morphology | 2.32535690 |
| 13 | MP0001873_stomach_inflammation | 2.31326548 |
| 14 | MP0003718_maternal_effect | 2.25843954 |
| 15 | MP0008872_abnormal_physiological_respon | 2.24010470 |
| 16 | MP0002837_dystrophic_cardiac_calcinosis | 2.17600120 |
| 17 | MP0001968_abnormal_touch/_nociception | 2.09681757 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 2.09441669 |
| 19 | MP0003300_gastrointestinal_ulcer | 2.08827157 |
| 20 | MP0003806_abnormal_nucleotide_metabolis | 2.02324027 |
| 21 | MP0005410_abnormal_fertilization | 2.01445926 |
| 22 | MP0000604_amyloidosis | 1.93423340 |
| 23 | MP0004381_abnormal_hair_follicle | 1.91512805 |
| 24 | MP0003646_muscle_fatigue | 1.88235791 |
| 25 | MP0004145_abnormal_muscle_electrophysio | 1.85340550 |
| 26 | MP0003693_abnormal_embryo_hatching | 1.83084155 |
| 27 | MP0002148_abnormal_hypersensitivity_rea | 1.80732451 |
| 28 | MP0005671_abnormal_response_to | 1.77585153 |
| 29 | MP0002736_abnormal_nociception_after | 1.76572834 |
| 30 | MP0002876_abnormal_thyroid_physiology | 1.74936351 |
| 31 | MP0002132_abnormal_respiratory_system | 1.73239729 |
| 32 | MP0003786_premature_aging | 1.68222904 |
| 33 | MP0000465_gastrointestinal_hemorrhage | 1.66054898 |
| 34 | MP0009333_abnormal_splenocyte_physiolog | 1.64728721 |
| 35 | MP0003186_abnormal_redox_activity | 1.54821062 |
| 36 | MP0006036_abnormal_mitochondrial_physio | 1.41318157 |
| 37 | MP0004147_increased_porphyrin_level | 1.40524324 |
| 38 | MP0001986_abnormal_taste_sensitivity | 1.37184984 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.36618611 |
| 40 | MP0004782_abnormal_surfactant_physiolog | 1.35555368 |
| 41 | MP0005646_abnormal_pituitary_gland | 1.35336038 |
| 42 | MP0001764_abnormal_homeostasis | 1.31062787 |
| 43 | MP0001905_abnormal_dopamine_level | 1.30095906 |
| 44 | MP0001529_abnormal_vocalization | 1.20930131 |
| 45 | MP0005310_abnormal_salivary_gland | 1.20457681 |
| 46 | MP0009697_abnormal_copulation | 1.18069422 |
| 47 | MP0009379_abnormal_foot_pigmentation | 1.17990734 |
| 48 | MP0002160_abnormal_reproductive_system | 1.15805280 |
| 49 | MP0004142_abnormal_muscle_tone | 1.15523655 |
| 50 | MP0001790_abnormal_immune_system | 1.15227455 |
| 51 | MP0005387_immune_system_phenotype | 1.15227455 |
| 52 | MP0005084_abnormal_gallbladder_morpholo | 1.14409592 |
| 53 | MP0008058_abnormal_DNA_repair | 1.13293555 |
| 54 | MP0005389_reproductive_system_phenotype | 1.12766635 |
| 55 | MP0002638_abnormal_pupillary_reflex | 1.09970194 |
| 56 | MP0000049_abnormal_middle_ear | 1.09725895 |
| 57 | MP0004957_abnormal_blastocyst_morpholog | 1.09199970 |
| 58 | MP0003195_calcinosis | 1.08689273 |
| 59 | MP0008877_abnormal_DNA_methylation | 1.08332389 |
| 60 | MP0005083_abnormal_biliary_tract | 1.07781411 |
| 61 | MP0002006_tumorigenesis | 1.05228366 |
| 62 | MP0005408_hypopigmentation | 0.93826317 |
| 63 | MP0004885_abnormal_endolymph | 0.91788124 |
| 64 | MP0002210_abnormal_sex_determination | 0.91556987 |
| 65 | MP0005636_abnormal_mineral_homeostasis | 0.89934871 |
| 66 | MP0003878_abnormal_ear_physiology | 0.86992925 |
| 67 | MP0005377_hearing/vestibular/ear_phenot | 0.86992925 |
| 68 | MP0001800_abnormal_humoral_immune | 0.85733396 |
| 69 | MP0009785_altered_susceptibility_to | 0.81962267 |
| 70 | MP0005645_abnormal_hypothalamus_physiol | 0.80060371 |
| 71 | MP0004133_heterotaxia | 0.79406769 |
| 72 | MP0008995_early_reproductive_senescence | 0.78135688 |
| 73 | MP0002254_reproductive_system_inflammat | 0.77972516 |
| 74 | MP0002166_altered_tumor_susceptibility | 0.77814167 |
| 75 | MP0001929_abnormal_gametogenesis | 0.77255553 |
| 76 | MP0001440_abnormal_grooming_behavior | 0.76755368 |
| 77 | MP0003077_abnormal_cell_cycle | 0.76686455 |
| 78 | MP0002735_abnormal_chemical_nociception | 0.76219235 |
| 79 | MP0001485_abnormal_pinna_reflex | 0.75402156 |
| 80 | MP0005167_abnormal_blood-brain_barrier | 0.72662143 |
| 81 | MP0008789_abnormal_olfactory_epithelium | 0.71319055 |
| 82 | MP0010094_abnormal_chromosome_stability | 0.70796028 |
| 83 | MP0009764_decreased_sensitivity_to | 0.68333043 |
| 84 | MP0002723_abnormal_immune_serum | 0.67648753 |
| 85 | MP0005395_other_phenotype | 0.66734281 |
| 86 | MP0003698_abnormal_male_reproductive | 0.66442772 |
| 87 | MP0001919_abnormal_reproductive_system | 0.66003620 |
| 88 | MP0005025_abnormal_response_to | 0.61954467 |
| 89 | MP0005551_abnormal_eye_electrophysiolog | 0.61847969 |
| 90 | MP0002272_abnormal_nervous_system | 0.61112444 |
| 91 | MP0003763_abnormal_thymus_physiology | 0.60428464 |
| 92 | MP0002693_abnormal_pancreas_physiology | 0.60047264 |
| 93 | MP0006072_abnormal_retinal_apoptosis | 0.59929160 |
| 94 | MP0009745_abnormal_behavioral_response | 0.59485585 |
| 95 | MP0003866_abnormal_defecation | 0.59005923 |
| 96 | MP0002405_respiratory_system_inflammati | 0.58820422 |
| 97 | MP0004215_abnormal_myocardial_fiber | 0.58427628 |
| 98 | MP0000490_abnormal_crypts_of | 0.58291179 |
| 99 | MP0005670_abnormal_white_adipose | 0.55976086 |
| 100 | MP0003011_delayed_dark_adaptation | 0.55616966 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 3-Methylglutaconic aciduria (HP:0003535) | 5.57428976 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 5.29668549 |
| 3 | Stomatitis (HP:0010280) | 5.11141044 |
| 4 | Acute encephalopathy (HP:0006846) | 4.55081484 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.54115296 |
| 6 | Progressive macrocephaly (HP:0004481) | 4.40256237 |
| 7 | Mitochondrial inheritance (HP:0001427) | 4.18735295 |
| 8 | Increased CSF lactate (HP:0002490) | 3.98558027 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.57421258 |
| 10 | Increased IgM level (HP:0003496) | 3.48532643 |
| 11 | Concave nail (HP:0001598) | 3.43915702 |
| 12 | Hepatic necrosis (HP:0002605) | 3.26820135 |
| 13 | Cerebral edema (HP:0002181) | 3.19551363 |
| 14 | Multiple enchondromatosis (HP:0005701) | 3.18104189 |
| 15 | Respiratory difficulties (HP:0002880) | 3.08303795 |
| 16 | Testicular atrophy (HP:0000029) | 3.02610627 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 2.97800825 |
| 18 | Increased serum lactate (HP:0002151) | 2.97719798 |
| 19 | IgG deficiency (HP:0004315) | 2.96049426 |
| 20 | Lactic acidosis (HP:0003128) | 2.72476124 |
| 21 | Congenital stationary night blindness (HP:0007642) | 2.72185728 |
| 22 | Optic disc pallor (HP:0000543) | 2.70677982 |
| 23 | Cleft eyelid (HP:0000625) | 2.66852775 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.64108751 |
| 25 | Respiratory failure (HP:0002878) | 2.61341342 |
| 26 | Lipid accumulation in hepatocytes (HP:0006561) | 2.58860940 |
| 27 | Conical tooth (HP:0000698) | 2.58304323 |
| 28 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.56764558 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.54542514 |
| 30 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.54542514 |
| 31 | Pendular nystagmus (HP:0012043) | 2.54179803 |
| 32 | Anhidrosis (HP:0000970) | 2.52554262 |
| 33 | Microvesicular hepatic steatosis (HP:0001414) | 2.51081612 |
| 34 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.48639118 |
| 35 | Pancreatic cysts (HP:0001737) | 2.48215946 |
| 36 | Abnormality of T cell physiology (HP:0011840) | 2.47782916 |
| 37 | Nephronophthisis (HP:0000090) | 2.46265613 |
| 38 | Macrocytic anemia (HP:0001972) | 2.44631721 |
| 39 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.40996997 |
| 40 | Exertional dyspnea (HP:0002875) | 2.35822302 |
| 41 | Abnormal pupillary function (HP:0007686) | 2.34573368 |
| 42 | Absent thumb (HP:0009777) | 2.29785440 |
| 43 | Leukodystrophy (HP:0002415) | 2.28136285 |
| 44 | Exercise intolerance (HP:0003546) | 2.27769631 |
| 45 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.26384382 |
| 46 | Hypoproteinemia (HP:0003075) | 2.25600023 |
| 47 | Abnormality of alanine metabolism (HP:0010916) | 2.23518522 |
| 48 | Hyperalaninemia (HP:0003348) | 2.23518522 |
| 49 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.23518522 |
| 50 | Sparse eyelashes (HP:0000653) | 2.20167254 |
| 51 | Abnormality of the anterior horn cell (HP:0006802) | 2.19968403 |
| 52 | Degeneration of anterior horn cells (HP:0002398) | 2.19968403 |
| 53 | Methylmalonic aciduria (HP:0012120) | 2.17696235 |
| 54 | Eosinophilia (HP:0001880) | 2.17289890 |
| 55 | Panhypogammaglobulinemia (HP:0003139) | 2.15418458 |
| 56 | Lethargy (HP:0001254) | 2.15279299 |
| 57 | Abnormality of the ileum (HP:0001549) | 2.11207902 |
| 58 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.09605746 |
| 59 | Abnormal number of erythroid precursors (HP:0012131) | 2.09550564 |
| 60 | Meckel diverticulum (HP:0002245) | 2.08799787 |
| 61 | Absent eyebrow (HP:0002223) | 2.08457346 |
| 62 | Abnormality of the renal medulla (HP:0100957) | 2.08325116 |
| 63 | Hypomagnesemia (HP:0002917) | 2.07455874 |
| 64 | Congenital, generalized hypertrichosis (HP:0004540) | 2.07262952 |
| 65 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.06168632 |
| 66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.00937177 |
| 67 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.98760937 |
| 68 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.98760937 |
| 69 | Hypoplasia of the thymus (HP:0000778) | 1.97813482 |
| 70 | Cerebral hypomyelination (HP:0006808) | 1.97186349 |
| 71 | Abnormality of magnesium homeostasis (HP:0004921) | 1.97086357 |
| 72 | Microretrognathia (HP:0000308) | 1.96888051 |
| 73 | Megaloblastic anemia (HP:0001889) | 1.95008045 |
| 74 | B lymphocytopenia (HP:0010976) | 1.94940592 |
| 75 | Severe combined immunodeficiency (HP:0004430) | 1.93684258 |
| 76 | Trismus (HP:0000211) | 1.92964920 |
| 77 | Autoimmune hemolytic anemia (HP:0001890) | 1.92389840 |
| 78 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.91201774 |
| 79 | Methylmalonic acidemia (HP:0002912) | 1.90481593 |
| 80 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.88966530 |
| 81 | Asplenia (HP:0001746) | 1.88796019 |
| 82 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.88157681 |
| 83 | Pancytopenia (HP:0001876) | 1.87554544 |
| 84 | Bilateral microphthalmos (HP:0007633) | 1.87411800 |
| 85 | Increased intramyocellular lipid droplets (HP:0012240) | 1.85968313 |
| 86 | Humeroradial synostosis (HP:0003041) | 1.85193914 |
| 87 | Synostosis involving the elbow (HP:0003938) | 1.85193914 |
| 88 | Abnormality of vitamin B metabolism (HP:0004340) | 1.83887289 |
| 89 | Mesangial abnormality (HP:0001966) | 1.82829809 |
| 90 | Thyroiditis (HP:0100646) | 1.82481087 |
| 91 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.82254458 |
| 92 | Confusion (HP:0001289) | 1.81295672 |
| 93 | Autoimmune thrombocytopenia (HP:0001973) | 1.81128838 |
| 94 | Abnormality of B cell number (HP:0010975) | 1.80533848 |
| 95 | Abnormality of urine glucose concentration (HP:0011016) | 1.79474081 |
| 96 | Glycosuria (HP:0003076) | 1.79474081 |
| 97 | Abnormality of eosinophils (HP:0001879) | 1.79297038 |
| 98 | Amniotic constriction ring (HP:0009775) | 1.77388345 |
| 99 | Abnormality of placental membranes (HP:0011409) | 1.77388345 |
| 100 | Tubular atrophy (HP:0000092) | 1.76937487 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 3.60684606 |
| 2 | VRK2 | 3.27435951 |
| 3 | NME2 | 3.24045544 |
| 4 | NME1 | 3.02082662 |
| 5 | SRPK1 | 2.97973751 |
| 6 | EIF2AK1 | 2.91157346 |
| 7 | NUAK1 | 2.85520282 |
| 8 | NEK1 | 2.46450980 |
| 9 | MST4 | 2.42515098 |
| 10 | ADRBK2 | 2.39599678 |
| 11 | SIK3 | 2.33104461 |
| 12 | TRIM28 | 2.18250883 |
| 13 | GRK1 | 2.16132367 |
| 14 | EIF2AK3 | 2.07034329 |
| 15 | TLK1 | 2.04721597 |
| 16 | TEC | 1.87233774 |
| 17 | PBK | 1.84114767 |
| 18 | PASK | 1.82834110 |
| 19 | BCKDK | 1.78778497 |
| 20 | MAP4K2 | 1.64828911 |
| 21 | ZAK | 1.64786163 |
| 22 | PINK1 | 1.61271953 |
| 23 | FRK | 1.58409981 |
| 24 | BUB1 | 1.44467725 |
| 25 | VRK1 | 1.40986894 |
| 26 | PAK4 | 1.40041989 |
| 27 | PLK3 | 1.38852321 |
| 28 | ITK | 1.37979954 |
| 29 | TAOK2 | 1.34085169 |
| 30 | CCNB1 | 1.33009544 |
| 31 | TXK | 1.32772603 |
| 32 | AKT3 | 1.27171482 |
| 33 | PLK4 | 1.26014290 |
| 34 | DYRK2 | 1.13535615 |
| 35 | CAMKK2 | 1.12489725 |
| 36 | PRKD3 | 1.08385015 |
| 37 | CDC7 | 1.07778788 |
| 38 | IKBKB | 1.06765561 |
| 39 | MAP3K9 | 1.00164877 |
| 40 | PNCK | 0.98923908 |
| 41 | EIF2AK2 | 0.98366546 |
| 42 | WNK3 | 0.94699587 |
| 43 | BCR | 0.93528798 |
| 44 | ABL2 | 0.85330461 |
| 45 | STK38L | 0.83439436 |
| 46 | PDK2 | 0.82618252 |
| 47 | SIK2 | 0.81719496 |
| 48 | ATR | 0.80379813 |
| 49 | CAMK1D | 0.76954439 |
| 50 | TAF1 | 0.76600946 |
| 51 | CAMK1G | 0.73495723 |
| 52 | INSRR | 0.73489394 |
| 53 | KIT | 0.70038850 |
| 54 | PLK2 | 0.70002559 |
| 55 | MARK3 | 0.67816763 |
| 56 | MKNK2 | 0.65395983 |
| 57 | AURKB | 0.64493403 |
| 58 | DAPK1 | 0.64273598 |
| 59 | PAK3 | 0.63241699 |
| 60 | STK4 | 0.61683546 |
| 61 | WNK4 | 0.61395368 |
| 62 | BTK | 0.61204727 |
| 63 | MKNK1 | 0.61003670 |
| 64 | TTK | 0.59011678 |
| 65 | CSNK2A2 | 0.57220542 |
| 66 | STK16 | 0.57189598 |
| 67 | PRKCE | 0.56999280 |
| 68 | AURKA | 0.55484926 |
| 69 | PIK3CG | 0.52627525 |
| 70 | PRKCI | 0.52356505 |
| 71 | PRKCG | 0.51925677 |
| 72 | RPS6KB2 | 0.50788290 |
| 73 | PRKCQ | 0.50690895 |
| 74 | RPS6KA5 | 0.50178266 |
| 75 | FES | 0.49875070 |
| 76 | CAMK1 | 0.49163183 |
| 77 | MAP3K11 | 0.48786719 |
| 78 | PHKG2 | 0.47462958 |
| 79 | PHKG1 | 0.47462958 |
| 80 | PLK1 | 0.45866539 |
| 81 | CSNK2A1 | 0.45286129 |
| 82 | JAK3 | 0.43563752 |
| 83 | NLK | 0.43124663 |
| 84 | IKBKE | 0.40751940 |
| 85 | CSNK1E | 0.40170950 |
| 86 | PRKG2 | 0.39313448 |
| 87 | PRKCD | 0.38464155 |
| 88 | OXSR1 | 0.37613433 |
| 89 | IGF1R | 0.37529573 |
| 90 | MAPKAPK3 | 0.37212611 |
| 91 | STK39 | 0.35151910 |
| 92 | ALK | 0.34331747 |
| 93 | SIK1 | 0.34096786 |
| 94 | MYLK | 0.33354376 |
| 95 | ADRBK1 | 0.33006396 |
| 96 | MAPK13 | 0.31830610 |
| 97 | GRK5 | 0.29785479 |
| 98 | TGFBR1 | 0.29553212 |
| 99 | CDK7 | 0.29104450 |
| 100 | SMG1 | 0.28343658 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.41078883 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.33452391 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.39917846 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.24571492 |
| 5 | Protein export_Homo sapiens_hsa03060 | 3.22728023 |
| 6 | Asthma_Homo sapiens_hsa05310 | 3.06761055 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.89652204 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.79253106 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.65264352 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.52263536 |
| 11 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.21091308 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.19671222 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.07807906 |
| 14 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.07123695 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.97784929 |
| 16 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.87167112 |
| 17 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.71493857 |
| 18 | Alzheimers disease_Homo sapiens_hsa05010 | 1.70656466 |
| 19 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.70249406 |
| 20 | RNA transport_Homo sapiens_hsa03013 | 1.66110195 |
| 21 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.63592749 |
| 22 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.58706482 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.57309046 |
| 24 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.55804189 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.47603443 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.43285252 |
| 27 | RNA degradation_Homo sapiens_hsa03018 | 1.41415936 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.37581328 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.36108826 |
| 30 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.35421731 |
| 31 | Spliceosome_Homo sapiens_hsa03040 | 1.31069553 |
| 32 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.31054259 |
| 33 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.31051730 |
| 34 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.29111261 |
| 35 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.23111776 |
| 36 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.22874257 |
| 37 | DNA replication_Homo sapiens_hsa03030 | 1.22381632 |
| 38 | Base excision repair_Homo sapiens_hsa03410 | 1.17030172 |
| 39 | Mismatch repair_Homo sapiens_hsa03430 | 1.08952438 |
| 40 | Purine metabolism_Homo sapiens_hsa00230 | 1.07728478 |
| 41 | Homologous recombination_Homo sapiens_hsa03440 | 1.03488332 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.01946903 |
| 43 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.01660962 |
| 44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.01504476 |
| 45 | Phototransduction_Homo sapiens_hsa04744 | 0.97324738 |
| 46 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.93218481 |
| 47 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.90848507 |
| 48 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.90558106 |
| 49 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.90286566 |
| 50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.80579974 |
| 51 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.74511343 |
| 52 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.74341680 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.73444968 |
| 54 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.68487876 |
| 55 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.59318342 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59112342 |
| 57 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.58040323 |
| 58 | Peroxisome_Homo sapiens_hsa04146 | 0.57509756 |
| 59 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.57416237 |
| 60 | Retinol metabolism_Homo sapiens_hsa00830 | 0.57405540 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.51559580 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51156115 |
| 63 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.50641449 |
| 64 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.50603638 |
| 65 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.50175846 |
| 66 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.48049491 |
| 67 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47377952 |
| 68 | Olfactory transduction_Homo sapiens_hsa04740 | 0.46994539 |
| 69 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.46576485 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.46368870 |
| 71 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.44188158 |
| 72 | Mineral absorption_Homo sapiens_hsa04978 | 0.42053194 |
| 73 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.41456959 |
| 74 | Sulfur relay system_Homo sapiens_hsa04122 | 0.41126558 |
| 75 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40377251 |
| 76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40201834 |
| 77 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.39494369 |
| 78 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.37587070 |
| 79 | Measles_Homo sapiens_hsa05162 | 0.37347033 |
| 80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.34362906 |
| 81 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.32114203 |
| 82 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.31865730 |
| 83 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.31315065 |
| 84 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.31241740 |
| 85 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.29945064 |
| 86 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.28834259 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.28528573 |
| 88 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.26952124 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.24989400 |
| 90 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.22229708 |
| 91 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.19865120 |
| 92 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.19171292 |
| 93 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.18255435 |
| 94 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.16944643 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.16536792 |
| 96 | Morphine addiction_Homo sapiens_hsa05032 | 0.16227477 |
| 97 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.16163713 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.14812206 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.13688701 |
| 100 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.12813486 |

