RPL29P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of regulatory T cell differentiation (GO:0045589)4.76951145
2regulation of chronic inflammatory response (GO:0002676)4.68826534
3positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)4.59368270
4cytidine deamination (GO:0009972)4.27742706
5cytidine metabolic process (GO:0046087)4.27742706
6cytidine catabolic process (GO:0006216)4.27742706
7regulation of isotype switching to IgG isotypes (GO:0048302)4.26648740
8DNA deamination (GO:0045006)4.18406253
9regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)4.12516518
10proteasome assembly (GO:0043248)4.11129146
11positive regulation of interleukin-17 production (GO:0032740)4.04197617
12regulation of response to tumor cell (GO:0002834)3.99455146
13positive regulation of response to tumor cell (GO:0002836)3.99455146
14positive regulation of immune response to tumor cell (GO:0002839)3.99455146
15regulation of immune response to tumor cell (GO:0002837)3.99455146
16positive regulation of interleukin-10 production (GO:0032733)3.97976722
17regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.85029062
18regulation of cellular amino acid metabolic process (GO:0006521)3.59864931
19positive regulation of isotype switching (GO:0045830)3.59752440
20maturation of SSU-rRNA (GO:0030490)3.55960150
21positive regulation of activated T cell proliferation (GO:0042104)3.52859776
22pyrimidine ribonucleoside catabolic process (GO:0046133)3.51211919
23CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.43480019
24positive regulation of DNA recombination (GO:0045911)3.40459349
25activated T cell proliferation (GO:0050798)3.36794602
26DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.36366264
27negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)3.34590164
28positive regulation of natural killer cell mediated cytotoxicity (GO:0045954)3.32999144
29water-soluble vitamin biosynthetic process (GO:0042364)3.32444118
30maturation of 5.8S rRNA (GO:0000460)3.30845601
31NADH metabolic process (GO:0006734)3.28251934
32GTP biosynthetic process (GO:0006183)3.25605996
33intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.25371061
34signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.25371061
35signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25071535
36signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25071535
37signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25071535
38negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)3.24122730
39negative regulation of T-helper cell differentiation (GO:0045623)3.24122730
40positive regulation of natural killer cell mediated immunity (GO:0002717)3.23544295
41positive regulation of leukocyte mediated cytotoxicity (GO:0001912)3.19040156
42respiratory chain complex IV assembly (GO:0008535)3.13496113
43positive regulation of B cell differentiation (GO:0045579)3.12521369
44signal transduction involved in DNA integrity checkpoint (GO:0072401)3.11842634
45signal transduction involved in DNA damage checkpoint (GO:0072422)3.11842634
46pseudouridine synthesis (GO:0001522)3.09710732
47positive regulation of antigen processing and presentation (GO:0002579)3.05941969
48negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.05778067
49regulation of interleukin-10 production (GO:0032653)3.05718266
50positive regulation of T cell mediated cytotoxicity (GO:0001916)3.05672266
51signal transduction involved in cell cycle checkpoint (GO:0072395)3.04906849
52necroptotic process (GO:0070266)3.04281102
53production of molecular mediator of immune response (GO:0002440)3.01888395
54positive regulation of interleukin-8 secretion (GO:2000484)3.01823813
55antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.00741568
56DNA catabolic process, exonucleolytic (GO:0000738)2.99288622
57cellular response to ATP (GO:0071318)2.99030130
58base-excision repair, AP site formation (GO:0006285)2.98878048
59positive regulation of immunoglobulin production (GO:0002639)2.92798205
60regulation of immunoglobulin secretion (GO:0051023)2.89592758
61ATP synthesis coupled proton transport (GO:0015986)2.88660437
62energy coupled proton transport, down electrochemical gradient (GO:0015985)2.88660437
63positive regulation of B cell mediated immunity (GO:0002714)2.88390987
64positive regulation of immunoglobulin mediated immune response (GO:0002891)2.88390987
65positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.87611672
66negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.87248039
67DNA demethylation (GO:0080111)2.84731910
68chaperone-mediated protein transport (GO:0072321)2.84113241
69UTP biosynthetic process (GO:0006228)2.83260918
70DNA double-strand break processing (GO:0000729)2.82481356
71regulation of RIG-I signaling pathway (GO:0039535)2.82126598
72mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.81859579
73negative regulation of ligase activity (GO:0051352)2.81104346
74negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.81104346
75regulation of leukocyte mediated cytotoxicity (GO:0001910)2.78270262
76positive regulation of T cell migration (GO:2000406)2.77608328
77antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.76814653
78regulation of natural killer cell mediated immunity (GO:0002715)2.76494131
79regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.76494131
80positive regulation of cell killing (GO:0031343)2.75096257
81intestinal epithelial cell development (GO:0060576)2.73173427
82cytochrome complex assembly (GO:0017004)2.72552639
83cellular response to cadmium ion (GO:0071276)2.71894951
84rRNA modification (GO:0000154)2.71352646
85negative regulation of B cell proliferation (GO:0030889)2.70274506
86T-helper cell differentiation (GO:0042093)2.69344726
87CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.69344726
88regulation of interleukin-8 secretion (GO:2000482)2.66639405
89regulation of T cell mediated cytotoxicity (GO:0001914)2.65507924
90regulation of cellular extravasation (GO:0002691)2.64570070
91positive regulation of cell cycle arrest (GO:0071158)2.63696744
92pyrimidine ribonucleoside metabolic process (GO:0046131)2.62813468
93positive regulation of natural killer cell differentiation (GO:0032825)2.62421320
94negative regulation of nitric oxide biosynthetic process (GO:0045019)2.61012893
95positive regulation of lymphocyte mediated immunity (GO:0002708)2.60087911
96regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.59990823
97DNA replication checkpoint (GO:0000076)2.59184311
98UTP metabolic process (GO:0046051)2.59108304
99L-fucose metabolic process (GO:0042354)2.57913483
100L-fucose catabolic process (GO:0042355)2.57913483

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.39230898
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.17276567
3ELF1_17652178_ChIP-ChIP_JURKAT_Human4.02036575
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.76055577
5IRF1_21803131_ChIP-Seq_MONOCYTES_Human3.54198618
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.29352675
7IRF8_22096565_ChIP-ChIP_GC-B_Human3.21940937
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.87690791
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.83004257
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.74242757
11SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.61690910
12VDR_22108803_ChIP-Seq_LS180_Human2.57402063
13E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.38644912
14VDR_23849224_ChIP-Seq_CD4+_Human2.37216600
15MYC_18555785_ChIP-Seq_MESCs_Mouse2.34159255
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.25755858
17GATA1_22025678_ChIP-Seq_K562_Human2.24936824
18FOXP3_21729870_ChIP-Seq_TREG_Human2.13283031
19NOTCH1_21737748_ChIP-Seq_TLL_Human2.05736597
20SRF_21415370_ChIP-Seq_HL-1_Mouse2.00469296
21IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.93049465
22STAT4_19710469_ChIP-ChIP_TH1__Mouse1.87186121
23BP1_19119308_ChIP-ChIP_Hs578T_Human1.87114316
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.83502871
25MYC_18358816_ChIP-ChIP_MESCs_Mouse1.71943590
26CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.69284481
27DCP1A_22483619_ChIP-Seq_HELA_Human1.68565153
28ZNF274_21170338_ChIP-Seq_K562_Hela1.67495204
29FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.66826648
30CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.66730545
31YY1_21170310_ChIP-Seq_MESCs_Mouse1.63872625
32STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.63240020
33CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.61790098
34CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.61766669
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.56371669
36EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.56288043
37HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.51895996
38PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.49124549
39CIITA_25753668_ChIP-Seq_RAJI_Human1.44219787
40ELK1_19687146_ChIP-ChIP_HELA_Human1.43894607
41GATA3_26560356_Chip-Seq_TH2_Human1.41896747
42ELK1_22589737_ChIP-Seq_MCF10A_Human1.40689664
43TP53_22573176_ChIP-Seq_HFKS_Human1.35755452
44HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.35609627
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.34933805
46IRF8_21731497_ChIP-ChIP_J774_Mouse1.33414525
47SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.32153415
48ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.32056874
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29752168
50MYC_19030024_ChIP-ChIP_MESCs_Mouse1.28421076
51SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.26793105
52TTF2_22483619_ChIP-Seq_HELA_Human1.26611461
53FOXA1_25329375_ChIP-Seq_VCAP_Human1.25735047
54FOXA1_27270436_Chip-Seq_PROSTATE_Human1.25735047
55IGF1R_20145208_ChIP-Seq_DFB_Human1.24756950
56XRN2_22483619_ChIP-Seq_HELA_Human1.23076227
57HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.22497036
58TAF2_19829295_ChIP-Seq_ESCs_Human1.21439904
59MYC_18940864_ChIP-ChIP_HL60_Human1.20267097
60GABP_19822575_ChIP-Seq_HepG2_Human1.20150870
61MYB_26560356_Chip-Seq_TH2_Human1.18458880
62EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.15729853
63PCGF2_27294783_Chip-Seq_ESCs_Mouse1.14682030
64PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.14545776
65NANOG_20526341_ChIP-Seq_ESCs_Human1.13252890
66FLI1_27457419_Chip-Seq_LIVER_Mouse1.13011714
67PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.10987977
68PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09556849
69E2F1_18555785_ChIP-Seq_MESCs_Mouse1.09532276
70SRY_22984422_ChIP-ChIP_TESTIS_Rat1.08537078
71TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.07891131
72EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.06449675
73AR_20517297_ChIP-Seq_VCAP_Human1.05032707
74RUNX_20019798_ChIP-Seq_JUKART_Human1.04695092
75BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.02057347
76NCOR_22424771_ChIP-Seq_293T_Human1.01797823
77AUTS2_25519132_ChIP-Seq_293T-REX_Human0.99743051
78OCT4_20526341_ChIP-Seq_ESCs_Human0.99443903
79LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98876727
80PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.97733251
81FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.97711959
82ERA_21632823_ChIP-Seq_H3396_Human0.96484576
83ERG_20517297_ChIP-Seq_VCAP_Human0.94886389
84RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.94507168
85STAT1_20625510_ChIP-Seq_HELA_Human0.93044586
86KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.92754837
87KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.92754837
88KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.92754837
89MYC_19829295_ChIP-Seq_ESCs_Human0.92465261
90FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92328254
91P53_21459846_ChIP-Seq_SAOS-2_Human0.91970261
92E2F1_20622854_ChIP-Seq_HELA_Human0.91816914
93SA1_27219007_Chip-Seq_Bcells_Human0.91198155
94GATA6_21074721_ChIP-Seq_CACO-2_Human0.88961210
95GATA3_21878914_ChIP-Seq_MCF-7_Human0.88337599
96SPI1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.87114008
97NFE2_27457419_Chip-Seq_LIVER_Mouse0.86873506
98TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.86670976
99BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.86450163
100CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.86198410

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001873_stomach_inflammation3.87557882
2MP0001348_abnormal_lacrimal_gland3.60379321
3MP0001835_abnormal_antigen_presentation3.45349277
4MP0002138_abnormal_hepatobiliary_system3.22294893
5MP0009333_abnormal_splenocyte_physiolog3.03940230
6MP0006082_CNS_inflammation2.95658522
7MP0005671_abnormal_response_to2.87241798
8MP0008875_abnormal_xenobiotic_pharmacok2.87154687
9MP0008872_abnormal_physiological_respon2.59795603
10MP0002163_abnormal_gland_morphology2.57298705
11MP0004147_increased_porphyrin_level2.48543654
12MP0009785_altered_susceptibility_to2.41430185
13MP0000685_abnormal_immune_system2.38799429
14MP0002148_abnormal_hypersensitivity_rea2.21370140
15MP0002876_abnormal_thyroid_physiology2.15116102
16MP0001790_abnormal_immune_system2.15032566
17MP0005387_immune_system_phenotype2.15032566
18MP0005360_urolithiasis2.10987725
19MP0005645_abnormal_hypothalamus_physiol2.07674853
20MP0010155_abnormal_intestine_physiology2.06000633
21MP0008058_abnormal_DNA_repair2.05930498
22MP0003303_peritoneal_inflammation2.03764532
23MP0001800_abnormal_humoral_immune1.95058659
24MP0003763_abnormal_thymus_physiology1.94545144
25MP0004145_abnormal_muscle_electrophysio1.91833789
26MP0003806_abnormal_nucleotide_metabolis1.88179757
27MP0001919_abnormal_reproductive_system1.85680355
28MP0005310_abnormal_salivary_gland1.70808635
29MP0005084_abnormal_gallbladder_morpholo1.68487262
30MP0005025_abnormal_response_to1.67390908
31MP0005000_abnormal_immune_tolerance1.67165301
32MP0005389_reproductive_system_phenotype1.66937100
33MP0002166_altered_tumor_susceptibility1.62199728
34MP0002723_abnormal_immune_serum1.58612386
35MP0003866_abnormal_defecation1.57066701
36MP0005379_endocrine/exocrine_gland_phen1.56619172
37MP0001663_abnormal_digestive_system1.55190775
38MP0002006_tumorigenesis1.53811174
39MP0002452_abnormal_antigen_presenting1.51917444
40MP0005085_abnormal_gallbladder_physiolo1.50326808
41MP0009379_abnormal_foot_pigmentation1.48623352
42MP0002420_abnormal_adaptive_immunity1.45041319
43MP0001666_abnormal_nutrient_absorption1.41043648
44MP0001845_abnormal_inflammatory_respons1.40159490
45MP0001819_abnormal_immune_cell1.39205280
46MP0001853_heart_inflammation1.37244988
47MP0003436_decreased_susceptibility_to1.36044118
48MP0009764_decreased_sensitivity_to1.36002501
49MP0003718_maternal_effect1.35516588
50MP0005408_hypopigmentation1.26948933
51MP0003724_increased_susceptibility_to1.26117290
52MP0005166_decreased_susceptibility_to1.24372377
53MP0006036_abnormal_mitochondrial_physio1.24237569
54MP0005174_abnormal_tail_pigmentation1.23327265
55MP0002139_abnormal_hepatobiliary_system1.21610599
56MP0005636_abnormal_mineral_homeostasis1.16336124
57MP0004019_abnormal_vitamin_homeostasis1.12662847
58MP0008469_abnormal_protein_level1.10335329
59MP0003693_abnormal_embryo_hatching1.09796108
60MP0003045_fibrosis1.09292009
61MP0001968_abnormal_touch/_nociception1.08103475
62MP0003567_abnormal_fetal_cardiomyocyte1.07616297
63MP0002277_abnormal_respiratory_mucosa1.05116832
64MP0003646_muscle_fatigue1.04433909
65MP0005410_abnormal_fertilization1.04060693
66MP0002405_respiratory_system_inflammati1.01541106
67MP0005165_increased_susceptibility_to1.00627270
68MP0004957_abnormal_blastocyst_morpholog1.00355083
69MP0001501_abnormal_sleep_pattern1.00215225
70MP0002419_abnormal_innate_immunity1.00020979
71MP0000716_abnormal_immune_system0.97270901
72MP0005381_digestive/alimentary_phenotyp0.97009314
73MP0005167_abnormal_blood-brain_barrier0.96804992
74MP0000689_abnormal_spleen_morphology0.95313105
75MP0000490_abnormal_crypts_of0.94980768
76MP0002398_abnormal_bone_marrow0.94136563
77MP0002160_abnormal_reproductive_system0.93842169
78MP0003786_premature_aging0.91620198
79MP0003186_abnormal_redox_activity0.91349292
80MP0001986_abnormal_taste_sensitivity0.91180630
81MP0004885_abnormal_endolymph0.89852454
82MP0001905_abnormal_dopamine_level0.88948238
83MP0003878_abnormal_ear_physiology0.88853483
84MP0005377_hearing/vestibular/ear_phenot0.88853483
85MP0005332_abnormal_amino_acid0.87556087
86MP0001764_abnormal_homeostasis0.85908844
87MP0009643_abnormal_urine_homeostasis0.85768908
88MP0002429_abnormal_blood_cell0.85517662
89MP0004782_abnormal_surfactant_physiolog0.85475820
90MP0005365_abnormal_bile_salt0.85152942
91MP0002102_abnormal_ear_morphology0.83850188
92MP0001664_abnormal_digestion0.82218815
93MP0005075_abnormal_melanosome_morpholog0.81662799
94MP0005584_abnormal_enzyme/coenzyme_acti0.79400174
95MP0000477_abnormal_intestine_morphology0.79077539
96MP0003075_altered_response_to0.77729930
97MP0009765_abnormal_xenobiotic_induced0.76252618
98MP0002722_abnormal_immune_system0.75402651
99MP0001765_abnormal_ion_homeostasis0.74818522
100MP0001881_abnormal_mammary_gland0.74539853

Predicted human phenotypes

RankGene SetZ-score
13-Methylglutaconic aciduria (HP:0003535)4.72989684
2Acute necrotizing encephalopathy (HP:0006965)4.42022009
3Abnormal mitochondria in muscle tissue (HP:0008316)4.10636076
4Hypoproteinemia (HP:0003075)3.91378070
5Progressive macrocephaly (HP:0004481)3.85886259
6Acute encephalopathy (HP:0006846)3.59248558
7Chronic diarrhea (HP:0002028)3.58958457
8Mitochondrial inheritance (HP:0001427)3.49016269
9Increased CSF lactate (HP:0002490)3.40253440
10Abnormal delayed hypersensitivity skin test (HP:0002963)3.27365204
11Autoimmune hemolytic anemia (HP:0001890)3.24376629
12Hepatocellular necrosis (HP:0001404)3.23971742
13Cerebral edema (HP:0002181)3.09863508
14Stomatitis (HP:0010280)3.09071818
15Pulmonary infiltrates (HP:0002113)3.02882187
16Hepatic necrosis (HP:0002605)3.01478325
17Abnormality of the prostate (HP:0008775)2.94598166
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.85118722
19Decreased activity of mitochondrial respiratory chain (HP:0008972)2.85118722
20Elevated erythrocyte sedimentation rate (HP:0003565)2.81071511
21Increased serum lactate (HP:0002151)2.79611714
22Gastrointestinal infarctions (HP:0005244)2.76215400
23Lethargy (HP:0001254)2.73582156
24Ketoacidosis (HP:0001993)2.65985810
25Abnormality of the pons (HP:0007361)2.65953995
26IgG deficiency (HP:0004315)2.64733979
27Abnormality of T cell physiology (HP:0011840)2.60475089
28Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.60312669
29Fatigue (HP:0012378)2.57182487
30Exertional dyspnea (HP:0002875)2.53015799
31Abnormal albumin level (HP:0012116)2.50373544
32Hypoalbuminemia (HP:0003073)2.50373544
33Degeneration of anterior horn cells (HP:0002398)2.49905319
34Abnormality of the anterior horn cell (HP:0006802)2.49905319
35Exercise intolerance (HP:0003546)2.49545353
36Reduced antithrombin III activity (HP:0001976)2.48604190
37Optic disc pallor (HP:0000543)2.48207491
38Abnormality of the vitamin B12 metabolism (HP:0004341)2.41158427
39Increased IgM level (HP:0003496)2.40414762
40Type I transferrin isoform profile (HP:0003642)2.39486911
41Increased intramyocellular lipid droplets (HP:0012240)2.36879777
42Lactic acidosis (HP:0003128)2.35582705
43Cerebral palsy (HP:0100021)2.33611304
44Abnormality of B cell number (HP:0010975)2.32538675
45Seborrheic dermatitis (HP:0001051)2.32262687
46Oral leukoplakia (HP:0002745)2.32164163
47Chest pain (HP:0100749)2.29753694
48Pulmonary fibrosis (HP:0002206)2.28656217
49Testicular atrophy (HP:0000029)2.28333322
50Abnormality of vitamin B metabolism (HP:0004340)2.27624170
51Generalized aminoaciduria (HP:0002909)2.27098839
52Aplastic anemia (HP:0001915)2.25536683
53Hypoplasia of the pons (HP:0012110)2.25531039
54Metabolic alkalosis (HP:0200114)2.25502643
55Respiratory failure (HP:0002878)2.18820390
56Abnormality of T cell number (HP:0011839)2.18806485
57Constricted visual fields (HP:0001133)2.18205391
58Abnormality of T cells (HP:0002843)2.17782794
59Skin rash (HP:0000988)2.17593438
60Increased muscle lipid content (HP:0009058)2.17088607
61Ketosis (HP:0001946)2.16873114
62Abnormal hemoglobin (HP:0011902)2.16637710
63Ureteral stenosis (HP:0000071)2.16106402
64Methylmalonic aciduria (HP:0012120)2.13720786
65Abnormality of glutamine family amino acid metabolism (HP:0010902)2.12616089
66Hypochromic anemia (HP:0001931)2.12163173
67Abnormality of dicarboxylic acid metabolism (HP:0010995)2.11267498
68Dicarboxylic aciduria (HP:0003215)2.11267498
69Abnormality of urine glucose concentration (HP:0011016)2.10582076
70Glycosuria (HP:0003076)2.10582076
71Alkalosis (HP:0001948)2.10312970
72Decreased electroretinogram (ERG) amplitude (HP:0000654)2.08775280
73Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.07337137
74Nausea (HP:0002018)2.06156785
75Amaurosis fugax (HP:0100576)2.04887541
76Leukodystrophy (HP:0002415)2.04825024
77Mediastinal lymphadenopathy (HP:0100721)2.02960705
78Absent rod-and cone-mediated responses on ERG (HP:0007688)2.02768385
79Hemoptysis (HP:0002105)2.01869676
80Progressive microcephaly (HP:0000253)2.01404704
81Amelogenesis imperfecta (HP:0000705)1.99052866
82Megaloblastic anemia (HP:0001889)1.97222034
83Conjunctival hamartoma (HP:0100780)1.96659815
84Vasculitis (HP:0002633)1.96590981
85Ureteral obstruction (HP:0006000)1.95902544
86Abnormality of aspartate family amino acid metabolism (HP:0010899)1.93443013
87Autoimmune thrombocytopenia (HP:0001973)1.85794689
88CNS demyelination (HP:0007305)1.84942921
89Cerebral hemorrhage (HP:0001342)1.84102083
90B lymphocytopenia (HP:0010976)1.83235513
91Pancreatitis (HP:0001733)1.83204585
92Tongue fasciculations (HP:0001308)1.81876913
93Pancytopenia (HP:0001876)1.81062964
94Pendular nystagmus (HP:0012043)1.79651325
95Abnormality of eosinophils (HP:0001879)1.79270052
96Eosinophilia (HP:0001880)1.77004523
97Chronic obstructive pulmonary disease (HP:0006510)1.74579056
98Obstructive lung disease (HP:0006536)1.74579056
99Concave nail (HP:0001598)1.73563159
100Abnormality of the pleura (HP:0002103)1.73496316

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TXK4.35461915
2TSSK64.03973823
3EIF2AK33.53123749
4VRK23.37651434
5TIE13.34694819
6EIF2AK13.28422931
7TLK13.20173583
8BMPR1B2.56420613
9GRK12.45481410
10MST42.39319773
11NEK12.16444113
12PBK2.11915609
13ADRBK21.97138818
14BCKDK1.85812339
15NME21.77288346
16FES1.77067661
17NME11.70591166
18IKBKB1.69499159
19ZAK1.68788318
20ITK1.62587885
21BUB11.61692777
22TEC1.59829693
23NUAK11.53537755
24FRK1.47535778
25SRPK11.46306045
26MAPKAPK31.41207864
27VRK11.39062470
28TAOK31.36684069
29MAP4K11.34930542
30JAK31.23646326
31MAP2K61.23491676
32IKBKE1.10757269
33TAF11.10615773
34KIT1.08966822
35MAP4K21.07785011
36CAMKK21.06489568
37OXSR11.02270494
38BCR0.90364692
39ACVR1B0.89123606
40PLK30.88503098
41TYK20.85230203
42PHKG10.83661927
43PHKG20.83661927
44PINK10.80720175
45KDR0.77935507
46WNK40.77274103
47EIF2AK20.75557223
48BTK0.74460067
49GRK60.72733959
50RIPK40.71954124
51DAPK10.70285264
52SMG10.69112300
53SYK0.68494754
54PASK0.68367682
55LCK0.65872489
56INSRR0.65657626
57CSK0.64386543
58ABL20.63118258
59BMPR20.62742696
60LYN0.58284157
61CLK10.58226151
62ERN10.56893902
63ALK0.56442787
64CSNK1A10.55618304
65CSNK1G30.55170131
66CSNK1G10.54800866
67ATR0.54016923
68MAP3K140.51851959
69IGF1R0.48954870
70PIM20.48527877
71DAPK20.48197313
72RPS6KB20.47546677
73TNIK0.47226991
74PDK20.46990211
75ZAP700.46580636
76TGFBR20.46252009
77TBK10.45014390
78RPS6KA50.43910793
79ADRBK10.43628842
80STK390.42409093
81CSNK1A1L0.42362251
82PRKCQ0.42339959
83PRKCA0.41999357
84MATK0.41988638
85PRKCD0.41787550
86PRKCI0.41175347
87CSNK2A20.37608631
88CSNK2A10.37229069
89MAP2K20.36247426
90GRK50.35983032
91PIM10.33988765
92NLK0.33870438
93CDK40.30401174
94PRKCE0.29395414
95MAPKAPK50.29077763
96AKT30.28854196
97PAK60.28274786
98DYRK20.28140031
99PRKACA0.27434522
100CAMKK10.27428072

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053104.48417545
2Allograft rejection_Homo sapiens_hsa053304.26059705
3Autoimmune thyroid disease_Homo sapiens_hsa053204.15448313
4Proteasome_Homo sapiens_hsa030503.98847071
5Intestinal immune network for IgA production_Homo sapiens_hsa046723.35137245
6Type I diabetes mellitus_Homo sapiens_hsa049403.14873698
7Graft-versus-host disease_Homo sapiens_hsa053323.12513099
8Oxidative phosphorylation_Homo sapiens_hsa001902.36342357
9Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.32218129
10Vitamin digestion and absorption_Homo sapiens_hsa049772.27960637
11Ribosome_Homo sapiens_hsa030102.00697508
12Parkinsons disease_Homo sapiens_hsa050121.72830635
13Antigen processing and presentation_Homo sapiens_hsa046121.71623230
14Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.66896922
15Rheumatoid arthritis_Homo sapiens_hsa053231.55278181
16Hematopoietic cell lineage_Homo sapiens_hsa046401.55228200
17Protein export_Homo sapiens_hsa030601.46500601
18Linoleic acid metabolism_Homo sapiens_hsa005911.46061495
19Fat digestion and absorption_Homo sapiens_hsa049751.45753531
20Cyanoamino acid metabolism_Homo sapiens_hsa004601.42965043
21alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.32212614
22Primary immunodeficiency_Homo sapiens_hsa053401.30004462
23DNA replication_Homo sapiens_hsa030301.20864071
24Mismatch repair_Homo sapiens_hsa034301.10674071
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.10090322
26Homologous recombination_Homo sapiens_hsa034401.08080086
27RNA polymerase_Homo sapiens_hsa030201.07807865
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.07619054
29One carbon pool by folate_Homo sapiens_hsa006701.07258353
30Base excision repair_Homo sapiens_hsa034101.06868945
31Sulfur metabolism_Homo sapiens_hsa009201.02316901
32Mineral absorption_Homo sapiens_hsa049781.01932869
33Caffeine metabolism_Homo sapiens_hsa002321.00269555
34Alzheimers disease_Homo sapiens_hsa050101.00166166
35Pyrimidine metabolism_Homo sapiens_hsa002400.99401790
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.97857182
37Huntingtons disease_Homo sapiens_hsa050160.96036240
38Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.95426890
39Phototransduction_Homo sapiens_hsa047440.94238404
40Staphylococcus aureus infection_Homo sapiens_hsa051500.93740980
41Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.92926978
42Nucleotide excision repair_Homo sapiens_hsa034200.89254222
43Viral myocarditis_Homo sapiens_hsa054160.88345963
44NOD-like receptor signaling pathway_Homo sapiens_hsa046210.86405580
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85156089
46NF-kappa B signaling pathway_Homo sapiens_hsa040640.84354039
47Leishmaniasis_Homo sapiens_hsa051400.82909152
48Tryptophan metabolism_Homo sapiens_hsa003800.81770654
49Arachidonic acid metabolism_Homo sapiens_hsa005900.79991298
50Ether lipid metabolism_Homo sapiens_hsa005650.79506848
51Spliceosome_Homo sapiens_hsa030400.78956897
52Measles_Homo sapiens_hsa051620.76568727
53Selenocompound metabolism_Homo sapiens_hsa004500.76524123
54Collecting duct acid secretion_Homo sapiens_hsa049660.75232211
55RNA degradation_Homo sapiens_hsa030180.72601018
56Chemical carcinogenesis_Homo sapiens_hsa052040.72388925
57Fanconi anemia pathway_Homo sapiens_hsa034600.71447921
58RNA transport_Homo sapiens_hsa030130.71241224
59Purine metabolism_Homo sapiens_hsa002300.67171266
60Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.64782376
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.64742004
62Renin-angiotensin system_Homo sapiens_hsa046140.63260890
63Nitrogen metabolism_Homo sapiens_hsa009100.62429786
64Histidine metabolism_Homo sapiens_hsa003400.61832755
652-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.59451693
66Herpes simplex infection_Homo sapiens_hsa051680.58562551
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57323257
68Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.56519277
69Glycerolipid metabolism_Homo sapiens_hsa005610.56209888
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.55996542
71Primary bile acid biosynthesis_Homo sapiens_hsa001200.55936883
72T cell receptor signaling pathway_Homo sapiens_hsa046600.55900073
73Retinol metabolism_Homo sapiens_hsa008300.55175001
74Cysteine and methionine metabolism_Homo sapiens_hsa002700.54547549
75Arginine and proline metabolism_Homo sapiens_hsa003300.53460427
76Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.52956509
77Metabolic pathways_Homo sapiens_hsa011000.52381620
78Maturity onset diabetes of the young_Homo sapiens_hsa049500.51641752
79Glutathione metabolism_Homo sapiens_hsa004800.50961349
80Peroxisome_Homo sapiens_hsa041460.50627330
81Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.50283596
82Fructose and mannose metabolism_Homo sapiens_hsa000510.49479439
83Arginine biosynthesis_Homo sapiens_hsa002200.48972529
84Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47977602
85Systemic lupus erythematosus_Homo sapiens_hsa053220.47442776
86Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.46848186
87Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.46717580
88Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46358596
89Basal transcription factors_Homo sapiens_hsa030220.44911422
90Non-homologous end-joining_Homo sapiens_hsa034500.43775496
91Sulfur relay system_Homo sapiens_hsa041220.42801073
92Jak-STAT signaling pathway_Homo sapiens_hsa046300.42480189
93beta-Alanine metabolism_Homo sapiens_hsa004100.41360390
94N-Glycan biosynthesis_Homo sapiens_hsa005100.40873979
95Steroid hormone biosynthesis_Homo sapiens_hsa001400.39756214
96Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39663448
97Fatty acid degradation_Homo sapiens_hsa000710.38712479
98Fatty acid elongation_Homo sapiens_hsa000620.38614755
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.37050520
100Propanoate metabolism_Homo sapiens_hsa006400.35802566

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