Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 7.51593439 |
2 | * viral transcription (GO:0019083) | 5.94525075 |
3 | * translational termination (GO:0006415) | 5.76973033 |
4 | maturation of SSU-rRNA (GO:0030490) | 5.30844987 |
5 | ribosomal small subunit biogenesis (GO:0042274) | 5.23087258 |
6 | * translational elongation (GO:0006414) | 5.20457014 |
7 | * SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.00309818 |
8 | * cotranslational protein targeting to membrane (GO:0006613) | 4.88440260 |
9 | * protein targeting to ER (GO:0045047) | 4.86284008 |
10 | * nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.76307715 |
11 | DNA unwinding involved in DNA replication (GO:0006268) | 4.71786985 |
12 | * establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.62407036 |
13 | * translational initiation (GO:0006413) | 4.58664023 |
14 | * protein localization to endoplasmic reticulum (GO:0070972) | 4.55073618 |
15 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.51019320 |
16 | * viral life cycle (GO:0019058) | 4.50611189 |
17 | * cellular protein complex disassembly (GO:0043624) | 4.50039394 |
18 | ribosomal large subunit biogenesis (GO:0042273) | 4.36732235 |
19 | formation of translation preinitiation complex (GO:0001731) | 4.35158832 |
20 | DNA strand elongation (GO:0022616) | 4.34045626 |
21 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.33161142 |
22 | * protein complex disassembly (GO:0043241) | 4.08385369 |
23 | DNA replication initiation (GO:0006270) | 3.98922257 |
24 | IMP biosynthetic process (GO:0006188) | 3.97944875 |
25 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.91064409 |
26 | telomere maintenance via recombination (GO:0000722) | 3.85690898 |
27 | * macromolecular complex disassembly (GO:0032984) | 3.81390012 |
28 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.75834507 |
29 | nucleobase biosynthetic process (GO:0046112) | 3.68023721 |
30 | mitotic recombination (GO:0006312) | 3.64144115 |
31 | IMP metabolic process (GO:0046040) | 3.58172809 |
32 | * mRNA catabolic process (GO:0006402) | 3.57905204 |
33 | negative regulation of mRNA processing (GO:0050686) | 3.51379121 |
34 | * RNA catabolic process (GO:0006401) | 3.45630245 |
35 | telomere maintenance via telomere lengthening (GO:0010833) | 3.44628189 |
36 | regulation of translational fidelity (GO:0006450) | 3.39186589 |
37 | negative regulation of mRNA metabolic process (GO:1903312) | 3.37186953 |
38 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.36776610 |
39 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.35178277 |
40 | * translation (GO:0006412) | 3.34345858 |
41 | protein localization to kinetochore (GO:0034501) | 3.33121030 |
42 | DNA deamination (GO:0045006) | 3.31547885 |
43 | rRNA processing (GO:0006364) | 3.30355758 |
44 | ribosome biogenesis (GO:0042254) | 3.28448777 |
45 | purine nucleobase biosynthetic process (GO:0009113) | 3.23179914 |
46 | rRNA metabolic process (GO:0016072) | 3.19209206 |
47 | * protein targeting to membrane (GO:0006612) | 3.15766995 |
48 | regulation of DNA damage checkpoint (GO:2000001) | 3.05106854 |
49 | negative regulation of RNA splicing (GO:0033119) | 3.04795433 |
50 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.03374878 |
51 | mitotic nuclear envelope disassembly (GO:0007077) | 3.02860546 |
52 | CENP-A containing nucleosome assembly (GO:0034080) | 3.00793042 |
53 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.97686981 |
54 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.97686981 |
55 | DNA replication checkpoint (GO:0000076) | 2.96879102 |
56 | DNA duplex unwinding (GO:0032508) | 2.96503849 |
57 | DNA geometric change (GO:0032392) | 2.94583148 |
58 | chromatin remodeling at centromere (GO:0031055) | 2.90928790 |
59 | telomere maintenance (GO:0000723) | 2.90665285 |
60 | L-serine metabolic process (GO:0006563) | 2.89769404 |
61 | telomere organization (GO:0032200) | 2.89306485 |
62 | viral mRNA export from host cell nucleus (GO:0046784) | 2.85821320 |
63 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 2.85632823 |
64 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.85632823 |
65 | pseudouridine synthesis (GO:0001522) | 2.84902738 |
66 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 2.82943937 |
67 | cellular component biogenesis (GO:0044085) | 2.82056095 |
68 | ribonucleoprotein complex assembly (GO:0022618) | 2.81338262 |
69 | translesion synthesis (GO:0019985) | 2.79497492 |
70 | DNA replication-independent nucleosome organization (GO:0034724) | 2.79199437 |
71 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.79199437 |
72 | GMP metabolic process (GO:0046037) | 2.77943073 |
73 | establishment of integrated proviral latency (GO:0075713) | 2.76818407 |
74 | regulation of translational initiation (GO:0006446) | 2.76745037 |
75 | membrane disassembly (GO:0030397) | 2.76658632 |
76 | nuclear envelope disassembly (GO:0051081) | 2.76658632 |
77 | nuclear pore organization (GO:0006999) | 2.76232692 |
78 | negative regulation of translational initiation (GO:0045947) | 2.75370474 |
79 | protein localization to chromosome, centromeric region (GO:0071459) | 2.75243129 |
80 | tRNA aminoacylation for protein translation (GO:0006418) | 2.73853293 |
81 | transcription from mitochondrial promoter (GO:0006390) | 2.73072752 |
82 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.72187559 |
83 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.71411489 |
84 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.70870915 |
85 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.70870915 |
86 | transcription-coupled nucleotide-excision repair (GO:0006283) | 2.70553438 |
87 | mRNA splicing, via spliceosome (GO:0000398) | 2.70052015 |
88 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 2.70052015 |
89 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.69712123 |
90 | RNA splicing, via transesterification reactions (GO:0000375) | 2.69271987 |
91 | establishment of viral latency (GO:0019043) | 2.69074518 |
92 | nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) | 2.68660405 |
93 | positive regulation of granulocyte differentiation (GO:0030854) | 2.67201243 |
94 | RNA export from nucleus (GO:0006405) | 2.66509841 |
95 | definitive hemopoiesis (GO:0060216) | 2.66509838 |
96 | pentose-phosphate shunt (GO:0006098) | 2.66188223 |
97 | spliceosomal snRNP assembly (GO:0000387) | 2.66072425 |
98 | protein-DNA complex disassembly (GO:0032986) | 2.65468871 |
99 | nucleosome disassembly (GO:0006337) | 2.65468871 |
100 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 2.64757963 |
101 | ribonucleoprotein complex subunit organization (GO:0071826) | 2.64080772 |
102 | rRNA modification (GO:0000154) | 2.63263647 |
103 | amino acid activation (GO:0043038) | 2.63260988 |
104 | tRNA aminoacylation (GO:0043039) | 2.63260988 |
105 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 2.63244189 |
106 | nuclear pore complex assembly (GO:0051292) | 2.62114834 |
107 | DNA topological change (GO:0006265) | 2.61408751 |
108 | ribosome assembly (GO:0042255) | 2.61187656 |
109 | NADPH regeneration (GO:0006740) | 2.61051314 |
110 | mismatch repair (GO:0006298) | 2.60713600 |
111 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.59284437 |
112 | histone H2A acetylation (GO:0043968) | 2.59261957 |
113 | ncRNA 3-end processing (GO:0043628) | 2.59068306 |
114 | postreplication repair (GO:0006301) | 2.58405600 |
115 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.58363919 |
116 | rRNA transcription (GO:0009303) | 2.58348479 |
117 | negative thymic T cell selection (GO:0045060) | 2.57700474 |
118 | positive regulation of B cell differentiation (GO:0045579) | 2.57019116 |
119 | negative regulation of DNA repair (GO:0045738) | 2.56818517 |
120 | ncRNA processing (GO:0034470) | 2.56808129 |
121 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.56413186 |
122 | non-recombinational repair (GO:0000726) | 2.56025952 |
123 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.56025952 |
124 | termination of RNA polymerase II transcription (GO:0006369) | 2.55391091 |
125 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.55374205 |
126 | * gene expression (GO:0010467) | 2.55320928 |
127 | T cell apoptotic process (GO:0070231) | 2.53511471 |
128 | histone H4-K8 acetylation (GO:0043982) | 2.52608075 |
129 | histone H4-K5 acetylation (GO:0043981) | 2.52608075 |
130 | kinetochore organization (GO:0051383) | 2.52396457 |
131 | positive regulation of histone H3-K4 methylation (GO:0051571) | 2.52341888 |
132 | DNA ligation (GO:0006266) | 2.52333678 |
133 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.51586635 |
134 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.50107783 |
135 | cell cycle G1/S phase transition (GO:0044843) | 2.50107783 |
136 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.49229878 |
137 | base-excision repair (GO:0006284) | 2.48301670 |
138 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.47648171 |
139 | mitotic metaphase plate congression (GO:0007080) | 2.46485632 |
140 | regulation of histone H3-K9 methylation (GO:0051570) | 2.45975419 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 8.38729479 |
2 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.13768217 |
3 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.79545153 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.23805661 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.94521788 |
6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.89036045 |
7 | * MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.86365004 |
8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.69435023 |
9 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.62698397 |
10 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.60055580 |
11 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.59230856 |
12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.54407505 |
13 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.52074456 |
14 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.51591442 |
15 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.51064317 |
16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.44784332 |
17 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.38327507 |
18 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.34777323 |
19 | * XRN2_22483619_ChIP-Seq_HELA_Human | 2.31650480 |
20 | MYC_22102868_ChIP-Seq_BL_Human | 2.28821550 |
21 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.26007865 |
22 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.22722762 |
23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.21567027 |
24 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.19500352 |
25 | * TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.12600614 |
26 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.10547248 |
27 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.07646137 |
28 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.00410643 |
29 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.86924908 |
30 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.85214193 |
31 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.81504303 |
32 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.80586144 |
33 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80187420 |
34 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.77060937 |
35 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.76469161 |
36 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.74595436 |
37 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.74577667 |
38 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.74304860 |
39 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.74016772 |
40 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.70730793 |
41 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.70664699 |
42 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.67674409 |
43 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.64870727 |
44 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64091489 |
45 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.63466431 |
46 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.63448904 |
47 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.62612726 |
48 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.60264592 |
49 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.58764736 |
50 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.57865252 |
51 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.56440905 |
52 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.50138847 |
53 | * POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49856602 |
54 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.48407467 |
55 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48262930 |
56 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.45532807 |
57 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.44867020 |
58 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.44772388 |
59 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.44347082 |
60 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.40455177 |
61 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.36320887 |
62 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.33653265 |
63 | * ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.33642873 |
64 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.31407277 |
65 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28844432 |
66 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.27095837 |
67 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.26395549 |
68 | * CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.25588604 |
69 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.24507847 |
70 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.23340146 |
71 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.22466488 |
72 | * CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.19913767 |
73 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.18642055 |
74 | MYB_26560356_Chip-Seq_TH2_Human | 1.16332151 |
75 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.15639576 |
76 | MAF_26560356_Chip-Seq_TH2_Human | 1.14639199 |
77 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.14605851 |
78 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.13731912 |
79 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.11704066 |
80 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.10909470 |
81 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.10909470 |
82 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.10909470 |
83 | MAF_26560356_Chip-Seq_TH1_Human | 1.08292458 |
84 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.07766631 |
85 | MYB_26560356_Chip-Seq_TH1_Human | 1.06859057 |
86 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.06312720 |
87 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.05975864 |
88 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.04464641 |
89 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.04212936 |
90 | UTX_26944678_Chip-Seq_JUKART_Human | 1.03659178 |
91 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.02040830 |
92 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.01873537 |
93 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00832935 |
94 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.00467841 |
95 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.98247030 |
96 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.98071852 |
97 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.97844870 |
98 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96829746 |
99 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.96294081 |
100 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.95615464 |
101 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.95547921 |
102 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.93487570 |
103 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92736321 |
104 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.91542992 |
105 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.90386539 |
106 | * KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.90291341 |
107 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.90217372 |
108 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.89792227 |
109 | * NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.89498214 |
110 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.89108520 |
111 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.88989914 |
112 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.88979580 |
113 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.88661485 |
114 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.86725131 |
115 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86628733 |
116 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.85473134 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 4.14772840 |
2 | MP0002396_abnormal_hematopoietic_system | 3.93972391 |
3 | MP0010094_abnormal_chromosome_stability | 3.83478353 |
4 | MP0008057_abnormal_DNA_replication | 3.42282189 |
5 | MP0004957_abnormal_blastocyst_morpholog | 3.36162596 |
6 | MP0003077_abnormal_cell_cycle | 3.25029330 |
7 | MP0003111_abnormal_nucleus_morphology | 3.22960968 |
8 | MP0008058_abnormal_DNA_repair | 2.89518407 |
9 | MP0004808_abnormal_hematopoietic_stem | 2.71849370 |
10 | MP0008007_abnormal_cellular_replicative | 2.67229480 |
11 | MP0003763_abnormal_thymus_physiology | 2.57680756 |
12 | MP0001835_abnormal_antigen_presentation | 2.24862327 |
13 | MP0010352_gastrointestinal_tract_polyps | 2.22358378 |
14 | MP0000490_abnormal_crypts_of | 2.10177948 |
15 | MP0005397_hematopoietic_system_phenotyp | 2.06327911 |
16 | MP0001545_abnormal_hematopoietic_system | 2.06327911 |
17 | MP0002398_abnormal_bone_marrow | 2.05098559 |
18 | MP0002254_reproductive_system_inflammat | 2.01669982 |
19 | MP0002163_abnormal_gland_morphology | 1.98163078 |
20 | MP0002009_preneoplasia | 1.96256735 |
21 | MP0006054_spinal_hemorrhage | 1.88132009 |
22 | MP0005671_abnormal_response_to | 1.87110532 |
23 | MP0009333_abnormal_splenocyte_physiolog | 1.85853287 |
24 | MP0000685_abnormal_immune_system | 1.80207781 |
25 | MP0000703_abnormal_thymus_morphology | 1.76324053 |
26 | MP0002722_abnormal_immune_system | 1.76185183 |
27 | MP0000350_abnormal_cell_proliferation | 1.76117639 |
28 | MP0000689_abnormal_spleen_morphology | 1.72689423 |
29 | MP0001800_abnormal_humoral_immune | 1.67211732 |
30 | MP0008932_abnormal_embryonic_tissue | 1.65624965 |
31 | MP0000465_gastrointestinal_hemorrhage | 1.63537006 |
32 | MP0005174_abnormal_tail_pigmentation | 1.62707988 |
33 | MP0003786_premature_aging | 1.62490749 |
34 | MP0010307_abnormal_tumor_latency | 1.61357489 |
35 | MP0001730_embryonic_growth_arrest | 1.60726784 |
36 | MP0008995_early_reproductive_senescence | 1.59695373 |
37 | MP0002019_abnormal_tumor_incidence | 1.59620798 |
38 | MP0009379_abnormal_foot_pigmentation | 1.58940992 |
39 | MP0002420_abnormal_adaptive_immunity | 1.57970962 |
40 | MP0002166_altered_tumor_susceptibility | 1.57794823 |
41 | MP0002429_abnormal_blood_cell | 1.57068709 |
42 | MP0000716_abnormal_immune_system | 1.56450800 |
43 | MP0001819_abnormal_immune_cell | 1.54671203 |
44 | MP0003123_paternal_imprinting | 1.48876922 |
45 | MP0002452_abnormal_antigen_presenting | 1.48442683 |
46 | MP0009785_altered_susceptibility_to | 1.46038181 |
47 | MP0005220_abnormal_exocrine_pancreas | 1.45118762 |
48 | MP0001873_stomach_inflammation | 1.43859180 |
49 | MP0005075_abnormal_melanosome_morpholog | 1.42504093 |
50 | MP0002095_abnormal_skin_pigmentation | 1.41309920 |
51 | MP0001661_extended_life_span | 1.41245572 |
52 | MP0005464_abnormal_platelet_physiology | 1.39157603 |
53 | MP0009672_abnormal_birth_weight | 1.39151305 |
54 | MP0002723_abnormal_immune_serum | 1.38246744 |
55 | MP0000313_abnormal_cell_death | 1.37652726 |
56 | MP0005379_endocrine/exocrine_gland_phen | 1.37482560 |
57 | MP0002006_tumorigenesis | 1.34257133 |
58 | MP0010155_abnormal_intestine_physiology | 1.30266690 |
59 | MP0008877_abnormal_DNA_methylation | 1.29898569 |
60 | MP0005025_abnormal_response_to | 1.29322771 |
61 | MP0003866_abnormal_defecation | 1.28577418 |
62 | MP0002405_respiratory_system_inflammati | 1.27284825 |
63 | MP0001853_heart_inflammation | 1.26865060 |
64 | MP0009278_abnormal_bone_marrow | 1.24727155 |
65 | MP0010234_abnormal_vibrissa_follicle | 1.24627859 |
66 | MP0002796_impaired_skin_barrier | 1.24074961 |
67 | MP0005000_abnormal_immune_tolerance | 1.22286075 |
68 | MP0002080_prenatal_lethality | 1.20151028 |
69 | MP0001697_abnormal_embryo_size | 1.18183174 |
70 | MP0000858_altered_metastatic_potential | 1.16718179 |
71 | MP0003436_decreased_susceptibility_to | 1.15144282 |
72 | MP0006035_abnormal_mitochondrial_morpho | 1.14474458 |
73 | MP0005501_abnormal_skin_physiology | 1.13702018 |
74 | MP0003567_abnormal_fetal_cardiomyocyte | 1.12247057 |
75 | MP0002148_abnormal_hypersensitivity_rea | 1.07631000 |
76 | MP0001672_abnormal_embryogenesis/_devel | 1.06932116 |
77 | MP0005380_embryogenesis_phenotype | 1.06932116 |
78 | MP0002132_abnormal_respiratory_system | 1.03569474 |
79 | MP0005387_immune_system_phenotype | 1.02910742 |
80 | MP0001790_abnormal_immune_system | 1.02910742 |
81 | MP0003984_embryonic_growth_retardation | 1.01235903 |
82 | MP0002086_abnormal_extraembryonic_tissu | 0.99542047 |
83 | MP0002088_abnormal_embryonic_growth/wei | 0.98228396 |
84 | MP0006036_abnormal_mitochondrial_physio | 0.97940197 |
85 | MP0009697_abnormal_copulation | 0.95204400 |
86 | MP0003943_abnormal_hepatobiliary_system | 0.94069588 |
87 | MP0009703_decreased_birth_body | 0.92715367 |
88 | MP0004381_abnormal_hair_follicle | 0.92223355 |
89 | MP0004197_abnormal_fetal_growth/weight/ | 0.92220274 |
90 | MP0003121_genomic_imprinting | 0.92049512 |
91 | MP0010030_abnormal_orbit_morphology | 0.90113277 |
92 | MP0002419_abnormal_innate_immunity | 0.90067178 |
93 | MP0000372_irregular_coat_pigmentation | 0.87752854 |
94 | MP0002084_abnormal_developmental_patter | 0.86635500 |
95 | MP0002085_abnormal_embryonic_tissue | 0.84600610 |
96 | MP0000613_abnormal_salivary_gland | 0.84374640 |
97 | MP0005023_abnormal_wound_healing | 0.83301988 |
98 | MP0001145_abnormal_male_reproductive | 0.82856070 |
99 | MP0004147_increased_porphyrin_level | 0.82085322 |
100 | MP0000678_abnormal_parathyroid_gland | 0.81610274 |
101 | MP0001845_abnormal_inflammatory_respons | 0.80550349 |
102 | MP0000598_abnormal_liver_morphology | 0.79791743 |
103 | MP0002938_white_spotting | 0.79626171 |
104 | MP0000477_abnormal_intestine_morphology | 0.78647566 |
105 | MP0001764_abnormal_homeostasis | 0.77984165 |
106 | MP0001348_abnormal_lacrimal_gland | 0.76388959 |
107 | MP0002111_abnormal_tail_morphology | 0.76037776 |
108 | MP0001293_anophthalmia | 0.74520221 |
109 | MP0002138_abnormal_hepatobiliary_system | 0.73396158 |
110 | MP0003806_abnormal_nucleotide_metabolis | 0.72844452 |
111 | MP0000358_abnormal_cell_content/ | 0.72558537 |
112 | MP0003718_maternal_effect | 0.71849369 |
113 | MP0008260_abnormal_autophagy | 0.70509069 |
114 | MP0000015_abnormal_ear_pigmentation | 0.68767172 |
115 | MP0000653_abnormal_sex_gland | 0.67442563 |
116 | MP0002877_abnormal_melanocyte_morpholog | 0.67249019 |
117 | MP0002075_abnormal_coat/hair_pigmentati | 0.66975732 |
118 | MP0004947_skin_inflammation | 0.66902930 |
119 | MP0002160_abnormal_reproductive_system | 0.66663740 |
120 | MP0005384_cellular_phenotype | 0.65757930 |
121 | MP0002933_joint_inflammation | 0.62980729 |
122 | MP0003448_altered_tumor_morphology | 0.62956320 |
123 | MP0005621_abnormal_cell_physiology | 0.62877254 |
124 | MP0006292_abnormal_olfactory_placode | 0.62231499 |
125 | MP0004264_abnormal_extraembryonic_tissu | 0.60321493 |
126 | MP0003724_increased_susceptibility_to | 0.59587688 |
127 | MP0000371_diluted_coat_color | 0.59323657 |
128 | MP0001915_intracranial_hemorrhage | 0.58984696 |
129 | MP0002210_abnormal_sex_determination | 0.57597977 |
130 | MP0003186_abnormal_redox_activity | 0.57144265 |
131 | MP0002089_abnormal_postnatal_growth/wei | 0.53681194 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.76758514 |
2 | Abnormal number of erythroid precursors (HP:0012131) | 5.41633497 |
3 | Reticulocytopenia (HP:0001896) | 5.34352577 |
4 | Thrombocytosis (HP:0001894) | 4.91710852 |
5 | Aplastic anemia (HP:0001915) | 4.19577053 |
6 | Microvesicular hepatic steatosis (HP:0001414) | 4.02432177 |
7 | Colon cancer (HP:0003003) | 3.92095077 |
8 | IgM deficiency (HP:0002850) | 3.57941234 |
9 | Pallor (HP:0000980) | 3.55527585 |
10 | 11 pairs of ribs (HP:0000878) | 3.52918746 |
11 | Macrocytic anemia (HP:0001972) | 3.43944167 |
12 | Birth length less than 3rd percentile (HP:0003561) | 3.29139298 |
13 | Myelodysplasia (HP:0002863) | 2.99723516 |
14 | Chronic otitis media (HP:0000389) | 2.97837956 |
15 | Petechiae (HP:0000967) | 2.89171904 |
16 | Oral leukoplakia (HP:0002745) | 2.83688964 |
17 | Amaurosis fugax (HP:0100576) | 2.82815181 |
18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.77265591 |
19 | Agnosia (HP:0010524) | 2.75925169 |
20 | Progressive muscle weakness (HP:0003323) | 2.73801914 |
21 | Medulloblastoma (HP:0002885) | 2.65510035 |
22 | Basal cell carcinoma (HP:0002671) | 2.61315395 |
23 | Multiple enchondromatosis (HP:0005701) | 2.60673888 |
24 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.57582064 |
25 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.57582064 |
26 | Lymphoma (HP:0002665) | 2.55407971 |
27 | Recurrent bronchitis (HP:0002837) | 2.53135519 |
28 | Selective tooth agenesis (HP:0001592) | 2.52585453 |
29 | Abnormality of T cell physiology (HP:0011840) | 2.48242862 |
30 | Abnormality of T cells (HP:0002843) | 2.46693080 |
31 | Severe combined immunodeficiency (HP:0004430) | 2.46057954 |
32 | Villous atrophy (HP:0011473) | 2.46037177 |
33 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.46037177 |
34 | Recurrent viral infections (HP:0004429) | 2.43503704 |
35 | Abnormality of the anterior horn cell (HP:0006802) | 2.43223712 |
36 | Degeneration of anterior horn cells (HP:0002398) | 2.43223712 |
37 | Abnormality of methionine metabolism (HP:0010901) | 2.42608573 |
38 | Ependymoma (HP:0002888) | 2.42367667 |
39 | Chromsome breakage (HP:0040012) | 2.42319831 |
40 | Hypoglycemic seizures (HP:0002173) | 2.41426695 |
41 | Neoplasm of the adrenal cortex (HP:0100641) | 2.40336870 |
42 | Seborrheic dermatitis (HP:0001051) | 2.39754996 |
43 | Poikiloderma (HP:0001029) | 2.31896397 |
44 | Panhypogammaglobulinemia (HP:0003139) | 2.29406005 |
45 | Prominent metopic ridge (HP:0005487) | 2.25080006 |
46 | Absent thumb (HP:0009777) | 2.24777564 |
47 | Myositis (HP:0100614) | 2.23384155 |
48 | Microretrognathia (HP:0000308) | 2.20124425 |
49 | Cutaneous melanoma (HP:0012056) | 2.19814423 |
50 | Premature graying of hair (HP:0002216) | 2.17537312 |
51 | IgG deficiency (HP:0004315) | 2.17132568 |
52 | Urethral obstruction (HP:0000796) | 2.15456137 |
53 | Diastasis recti (HP:0001540) | 2.15009233 |
54 | Acute myeloid leukemia (HP:0004808) | 2.14183695 |
55 | Prolonged bleeding time (HP:0003010) | 2.13806216 |
56 | Asplenia (HP:0001746) | 2.12596267 |
57 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 2.11653563 |
58 | Bone marrow hypocellularity (HP:0005528) | 2.10561652 |
59 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.09742493 |
60 | Combined immunodeficiency (HP:0005387) | 2.09314889 |
61 | Abnormality of the preputium (HP:0100587) | 2.09135694 |
62 | Abnormality of chromosome stability (HP:0003220) | 2.07739423 |
63 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.06020520 |
64 | Rough bone trabeculation (HP:0100670) | 2.06000421 |
65 | Neoplasm of the pancreas (HP:0002894) | 2.05916168 |
66 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.05590641 |
67 | T lymphocytopenia (HP:0005403) | 2.05192078 |
68 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.04685421 |
69 | Pancytopenia (HP:0001876) | 2.04073215 |
70 | Type I transferrin isoform profile (HP:0003642) | 2.02542753 |
71 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.01384804 |
72 | Lymphopenia (HP:0001888) | 2.01142420 |
73 | Progressive external ophthalmoplegia (HP:0000590) | 2.00473286 |
74 | Horseshoe kidney (HP:0000085) | 1.99569495 |
75 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.99291030 |
76 | Abnormality of the fingertips (HP:0001211) | 1.98543870 |
77 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.96972094 |
78 | Missing ribs (HP:0000921) | 1.96629516 |
79 | Glossoptosis (HP:0000162) | 1.95989697 |
80 | Abnormality of B cell number (HP:0010975) | 1.95500420 |
81 | B lymphocytopenia (HP:0010976) | 1.95500420 |
82 | Optic nerve coloboma (HP:0000588) | 1.95280064 |
83 | Abnormal number of incisors (HP:0011064) | 1.93419839 |
84 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.93345842 |
85 | Cellular immunodeficiency (HP:0005374) | 1.93181272 |
86 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.92761119 |
87 | Patellar aplasia (HP:0006443) | 1.90563545 |
88 | Thoracic kyphosis (HP:0002942) | 1.90522453 |
89 | Viral hepatitis (HP:0006562) | 1.90504192 |
90 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.89452439 |
91 | Abnormality of T cell number (HP:0011839) | 1.88851892 |
92 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.88416718 |
93 | Acute lymphatic leukemia (HP:0006721) | 1.87509172 |
94 | Carpal bone hypoplasia (HP:0001498) | 1.87058135 |
95 | Homocystinuria (HP:0002156) | 1.85572382 |
96 | Abnormality of homocysteine metabolism (HP:0010919) | 1.85572382 |
97 | Abnormality of the thymus (HP:0000777) | 1.84700395 |
98 | Premature ovarian failure (HP:0008209) | 1.84517014 |
99 | Abnormality of the metopic suture (HP:0005556) | 1.84164550 |
100 | High anterior hairline (HP:0009890) | 1.83454721 |
101 | Embryonal renal neoplasm (HP:0011794) | 1.82609440 |
102 | Muscle fiber atrophy (HP:0100295) | 1.82416048 |
103 | Squamous cell carcinoma (HP:0002860) | 1.82360019 |
104 | Abnormality of reticulocytes (HP:0004312) | 1.81767813 |
105 | Abnormality of DNA repair (HP:0003254) | 1.81454578 |
106 | Volvulus (HP:0002580) | 1.81057535 |
107 | Neoplasm of the colon (HP:0100273) | 1.80055893 |
108 | Meckel diverticulum (HP:0002245) | 1.79593262 |
109 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.77535765 |
110 | Entropion (HP:0000621) | 1.77331694 |
111 | Depressed nasal ridge (HP:0000457) | 1.76416689 |
112 | Increased nuchal translucency (HP:0010880) | 1.76155645 |
113 | Anteriorly placed anus (HP:0001545) | 1.75263807 |
114 | Gastrointestinal inflammation (HP:0004386) | 1.75231286 |
115 | Autoimmune hemolytic anemia (HP:0001890) | 1.75023161 |
116 | Irregular epiphyses (HP:0010582) | 1.73829957 |
117 | Abnormality of the ileum (HP:0001549) | 1.73764139 |
118 | Cellulitis (HP:0100658) | 1.73178633 |
119 | Deviation of the thumb (HP:0009603) | 1.72820932 |
120 | Neoplasm of the adrenal gland (HP:0100631) | 1.72436381 |
121 | Proximal placement of thumb (HP:0009623) | 1.72362615 |
122 | Agammaglobulinemia (HP:0004432) | 1.71818959 |
123 | Abnormality of the calcaneus (HP:0008364) | 1.71709463 |
124 | Type 2 muscle fiber atrophy (HP:0003554) | 1.71486929 |
125 | Breast hypoplasia (HP:0003187) | 1.70869011 |
126 | Triphalangeal thumb (HP:0001199) | 1.68845997 |
127 | Slow saccadic eye movements (HP:0000514) | 1.68645507 |
128 | Verrucae (HP:0200043) | 1.68319453 |
129 | Papilloma (HP:0012740) | 1.68319453 |
130 | Adenoma sebaceum (HP:0009720) | 1.68129633 |
131 | Angiofibromas (HP:0010615) | 1.68129633 |
132 | Cholecystitis (HP:0001082) | 1.66868266 |
133 | Abnormal gallbladder physiology (HP:0012438) | 1.66868266 |
134 | Abnormality of the prostate (HP:0008775) | 1.66579879 |
135 | Deep palmar crease (HP:0006191) | 1.66578518 |
136 | Respiratory difficulties (HP:0002880) | 1.66298804 |
137 | Rhabdomyosarcoma (HP:0002859) | 1.65915289 |
138 | Small intestinal stenosis (HP:0012848) | 1.65683327 |
139 | Duodenal stenosis (HP:0100867) | 1.65683327 |
140 | Sloping forehead (HP:0000340) | 1.65272560 |
141 | IgA deficiency (HP:0002720) | 1.64771705 |
142 | Atresia of the external auditory canal (HP:0000413) | 1.64108095 |
143 | Trismus (HP:0000211) | 1.62784852 |
144 | Recurrent fungal infections (HP:0002841) | 1.62490554 |
145 | Tongue fasciculations (HP:0001308) | 1.62457392 |
146 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.62075474 |
147 | Abnormality of the thoracic spine (HP:0100711) | 1.61990480 |
148 | Broad palm (HP:0001169) | 1.61706278 |
149 | Pulmonary fibrosis (HP:0002206) | 1.61281828 |
150 | Colitis (HP:0002583) | 1.60277853 |
151 | Asymmetry of the thorax (HP:0001555) | 1.57664914 |
152 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.54650854 |
153 | Dicarboxylic aciduria (HP:0003215) | 1.54650854 |
154 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 1.54272402 |
155 | Anal stenosis (HP:0002025) | 1.53688400 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SMG1 | 3.92381897 |
2 | VRK2 | 3.80061315 |
3 | EEF2K | 3.57219856 |
4 | WEE1 | 3.30608743 |
5 | TSSK6 | 3.16478391 |
6 | CDC7 | 3.11439037 |
7 | PASK | 2.95801547 |
8 | BUB1 | 2.84856719 |
9 | MAP4K1 | 2.79177845 |
10 | NME2 | 2.78988765 |
11 | TGFBR1 | 2.78753284 |
12 | RPS6KB2 | 2.55119797 |
13 | PRPF4B | 2.52227523 |
14 | TAF1 | 2.14407924 |
15 | FLT3 | 2.08558297 |
16 | PBK | 1.95001656 |
17 | EIF2AK1 | 1.94682023 |
18 | STK16 | 1.93035621 |
19 | SRPK1 | 1.87953362 |
20 | MKNK1 | 1.77411851 |
21 | VRK1 | 1.75494377 |
22 | KIT | 1.74338250 |
23 | PKN2 | 1.71890650 |
24 | BTK | 1.70154848 |
25 | NEK2 | 1.70065709 |
26 | BRSK2 | 1.67666168 |
27 | NUAK1 | 1.61400349 |
28 | ACVR1B | 1.57783046 |
29 | ATR | 1.57609979 |
30 | MAP2K3 | 1.57578945 |
31 | PIM2 | 1.53616328 |
32 | LRRK2 | 1.52322901 |
33 | ZAP70 | 1.49260030 |
34 | TEC | 1.46781350 |
35 | TXK | 1.45765791 |
36 | EIF2AK3 | 1.41257693 |
37 | RPS6KA4 | 1.35687937 |
38 | CDK7 | 1.31833122 |
39 | STK10 | 1.30861703 |
40 | AURKB | 1.28978135 |
41 | JAK3 | 1.25344106 |
42 | FGFR2 | 1.23904294 |
43 | NEK1 | 1.17928268 |
44 | DYRK3 | 1.16962144 |
45 | PIM1 | 1.16832470 |
46 | BCKDK | 1.15687437 |
47 | FES | 1.14215893 |
48 | PLK1 | 1.13514075 |
49 | CDK4 | 1.11057168 |
50 | SCYL2 | 1.09906597 |
51 | PAK4 | 1.08307299 |
52 | CDK8 | 1.05679305 |
53 | CCNB1 | 1.04593288 |
54 | PLK3 | 1.04429312 |
55 | TLK1 | 1.02825072 |
56 | HIPK2 | 1.02422617 |
57 | CSF1R | 1.01848685 |
58 | TTK | 0.95245720 |
59 | SYK | 0.94151962 |
60 | CLK1 | 0.92804490 |
61 | MAP3K10 | 0.91956508 |
62 | FGFR4 | 0.91233223 |
63 | MAP3K8 | 0.90157603 |
64 | PLK4 | 0.89441338 |
65 | EIF2AK2 | 0.89350818 |
66 | TESK2 | 0.84076806 |
67 | MKNK2 | 0.83376107 |
68 | BRSK1 | 0.83193356 |
69 | CHEK1 | 0.83094426 |
70 | STK4 | 0.82824318 |
71 | MAPKAPK3 | 0.80807087 |
72 | GRK6 | 0.76188984 |
73 | TRIB3 | 0.74572033 |
74 | ITK | 0.72041833 |
75 | MST4 | 0.71061032 |
76 | TYK2 | 0.70770642 |
77 | LCK | 0.69073353 |
78 | PRKD3 | 0.67062280 |
79 | CDK19 | 0.66937689 |
80 | IKBKB | 0.64747092 |
81 | CDK9 | 0.63856130 |
82 | CHEK2 | 0.63819185 |
83 | ILK | 0.62898579 |
84 | CSNK2A2 | 0.62589913 |
85 | TAOK3 | 0.62365080 |
86 | ALK | 0.61673753 |
87 | TNK2 | 0.61271425 |
88 | LYN | 0.60731332 |
89 | ATM | 0.59032997 |
90 | ZAK | 0.58648064 |
91 | IRAK4 | 0.58393792 |
92 | CDK6 | 0.58137836 |
93 | SIK3 | 0.57350384 |
94 | MAP3K14 | 0.55577303 |
95 | MAP2K6 | 0.55137169 |
96 | MATK | 0.55114650 |
97 | IKBKE | 0.54692788 |
98 | BRD4 | 0.54665687 |
99 | RPS6KA6 | 0.54574296 |
100 | BLK | 0.54252371 |
101 | CDK2 | 0.53086858 |
102 | NME1 | 0.53072911 |
103 | MAP3K12 | 0.52494102 |
104 | HCK | 0.52268767 |
105 | CSNK2A1 | 0.51441080 |
106 | RPS6KC1 | 0.50690941 |
107 | RPS6KL1 | 0.50690941 |
108 | MAP4K2 | 0.49864261 |
109 | TBK1 | 0.49576464 |
110 | MAP2K2 | 0.49229495 |
111 | DAPK1 | 0.49214622 |
112 | AURKA | 0.47496497 |
113 | FGFR3 | 0.45910992 |
114 | KDR | 0.43440297 |
115 | MAP3K3 | 0.42265798 |
116 | RPS6KA5 | 0.42113183 |
117 | RPS6KB1 | 0.39763540 |
118 | NEK9 | 0.38722544 |
119 | PAK2 | 0.37607987 |
120 | NLK | 0.37602430 |
121 | CHUK | 0.37487680 |
122 | PDK2 | 0.36981128 |
123 | STK3 | 0.35886701 |
124 | CDK12 | 0.34387393 |
125 | EPHA2 | 0.33670596 |
126 | PAK1 | 0.32704028 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.83539533 |
2 | * Ribosome_Homo sapiens_hsa03010 | 4.72445789 |
3 | Mismatch repair_Homo sapiens_hsa03430 | 4.12930085 |
4 | Base excision repair_Homo sapiens_hsa03410 | 3.08221649 |
5 | Spliceosome_Homo sapiens_hsa03040 | 3.05749799 |
6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.91675510 |
7 | Proteasome_Homo sapiens_hsa03050 | 2.80349251 |
8 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.70486521 |
9 | Homologous recombination_Homo sapiens_hsa03440 | 2.61414875 |
10 | RNA transport_Homo sapiens_hsa03013 | 2.53047712 |
11 | RNA polymerase_Homo sapiens_hsa03020 | 2.50914428 |
12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.31362691 |
13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.25257780 |
14 | Cell cycle_Homo sapiens_hsa04110 | 2.21942422 |
15 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.12891404 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.11501871 |
17 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.84302403 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.84264740 |
19 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.72508694 |
20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.56763307 |
21 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.53569286 |
22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.51190275 |
23 | Carbon metabolism_Homo sapiens_hsa01200 | 1.40890820 |
24 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.39152493 |
25 | Basal transcription factors_Homo sapiens_hsa03022 | 1.39052232 |
26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.38537684 |
27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.34937738 |
28 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.31734765 |
29 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.26009534 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.21683711 |
31 | Purine metabolism_Homo sapiens_hsa00230 | 1.11422075 |
32 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.10925313 |
33 | Measles_Homo sapiens_hsa05162 | 1.07005327 |
34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.04874943 |
35 | Legionellosis_Homo sapiens_hsa05134 | 1.04533473 |
36 | Protein export_Homo sapiens_hsa03060 | 1.02101605 |
37 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.00589361 |
38 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.00222408 |
39 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.94492370 |
40 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.90933962 |
41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.88787320 |
42 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.86944644 |
43 | HTLV-I infection_Homo sapiens_hsa05166 | 0.85872029 |
44 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.85810326 |
45 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.83622556 |
46 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.80475453 |
47 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.77956552 |
48 | Leishmaniasis_Homo sapiens_hsa05140 | 0.76502851 |
49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.76259986 |
50 | Lysine degradation_Homo sapiens_hsa00310 | 0.75794381 |
51 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.75443773 |
52 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.74669620 |
53 | Thyroid cancer_Homo sapiens_hsa05216 | 0.71534343 |
54 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.70282205 |
55 | Shigellosis_Homo sapiens_hsa05131 | 0.70014729 |
56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.69730765 |
57 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.69446589 |
58 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.69411006 |
59 | Hepatitis B_Homo sapiens_hsa05161 | 0.68994205 |
60 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68052664 |
61 | Apoptosis_Homo sapiens_hsa04210 | 0.67405657 |
62 | Allograft rejection_Homo sapiens_hsa05330 | 0.65896347 |
63 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.65511801 |
64 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.62792966 |
65 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.62378873 |
66 | Influenza A_Homo sapiens_hsa05164 | 0.62175909 |
67 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.60925050 |
68 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.60192548 |
69 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.59822405 |
70 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.57983431 |
71 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.55952776 |
72 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.55585941 |
73 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.55349033 |
74 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.54840088 |
75 | Prostate cancer_Homo sapiens_hsa05215 | 0.53139826 |
76 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.52473491 |
77 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.52153132 |
78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.48705463 |
79 | Colorectal cancer_Homo sapiens_hsa05210 | 0.46852331 |
80 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.46600732 |
81 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.44214013 |
82 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.43754488 |
83 | Platelet activation_Homo sapiens_hsa04611 | 0.42753364 |
84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41983038 |
85 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.41822813 |
86 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.41418141 |
87 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.41348600 |
88 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.41016761 |
89 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.40174741 |
90 | Alcoholism_Homo sapiens_hsa05034 | 0.39637870 |
91 | Sulfur relay system_Homo sapiens_hsa04122 | 0.39468607 |
92 | Viral myocarditis_Homo sapiens_hsa05416 | 0.39407703 |
93 | Endometrial cancer_Homo sapiens_hsa05213 | 0.38677724 |
94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.38631382 |
95 | Asthma_Homo sapiens_hsa05310 | 0.38269728 |
96 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.37865179 |
97 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.37191061 |
98 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.36897107 |
99 | Galactose metabolism_Homo sapiens_hsa00052 | 0.36873693 |
100 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.36150040 |
101 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.36105061 |
102 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.35474043 |
103 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35174622 |
104 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.33939161 |
105 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.33630715 |
106 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.33432271 |
107 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.32802343 |
108 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.31601507 |
109 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.31242311 |
110 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.31076277 |
111 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.30645465 |
112 | Other glycan degradation_Homo sapiens_hsa00511 | 0.29738294 |
113 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.28688608 |
114 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.28558136 |
115 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27765830 |
116 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.26765811 |
117 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.26383868 |
118 | Metabolic pathways_Homo sapiens_hsa01100 | 0.26366446 |
119 | Pathways in cancer_Homo sapiens_hsa05200 | 0.24767296 |
120 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.24640588 |
121 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.24479269 |
122 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.24353847 |
123 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.24270543 |
124 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.24110656 |
125 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.23367017 |
126 | Pertussis_Homo sapiens_hsa05133 | 0.22765241 |
127 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.22392425 |
128 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.20697746 |