RPL30

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30E family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U72 small nucleolar RNA gene, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)9.76830098
2* cotranslational protein targeting to membrane (GO:0006613)9.62889550
3* protein targeting to ER (GO:0045047)9.60572039
4* translational elongation (GO:0006414)9.57756151
5* establishment of protein localization to endoplasmic reticulum (GO:0072599)9.22074890
6* protein localization to endoplasmic reticulum (GO:0070972)8.99031881
7* cellular protein complex disassembly (GO:0043624)8.91424370
8* viral life cycle (GO:0019058)8.91122539
9* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)8.84341703
10maturation of SSU-rRNA (GO:0030490)8.84217342
11* translational initiation (GO:0006413)8.14731928
12* protein complex disassembly (GO:0043241)7.69772953
13ribosomal large subunit biogenesis (GO:0042273)7.20809454
14* macromolecular complex disassembly (GO:0032984)7.16144781
15* protein targeting to membrane (GO:0006612)6.45479495
16* nuclear-transcribed mRNA catabolic process (GO:0000956)6.16849475
17* mRNA catabolic process (GO:0006402)5.86276301
18* translation (GO:0006412)5.58103393
19* RNA catabolic process (GO:0006401)5.34637301
20ribonucleoprotein complex biogenesis (GO:0022613)5.15160862
21* establishment of protein localization to membrane (GO:0090150)4.33972628
22mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.04880469
23rRNA processing (GO:0006364)3.99302410
24formation of translation preinitiation complex (GO:0001731)3.90031344
25* protein targeting (GO:0006605)3.88899776
26ATP synthesis coupled proton transport (GO:0015986)3.88341276
27energy coupled proton transport, down electrochemical gradient (GO:0015985)3.88341276
28cellular component biogenesis (GO:0044085)3.85069792
29rRNA metabolic process (GO:0016072)3.84068526
30* establishment of protein localization to organelle (GO:0072594)3.80862105
31* protein localization to membrane (GO:0072657)3.36765709
32ncRNA 3-end processing (GO:0043628)3.22315634
33DNA deamination (GO:0045006)3.18335627
34establishment of integrated proviral latency (GO:0075713)3.12670310
35inner mitochondrial membrane organization (GO:0007007)3.10746244
36sequestering of actin monomers (GO:0042989)3.08387582
37viral protein processing (GO:0019082)3.03136919
38* cellular component disassembly (GO:0022411)3.01362774
39ATP biosynthetic process (GO:0006754)2.98270429
40negative regulation of RNA splicing (GO:0033119)2.98193480
41chaperone-mediated protein transport (GO:0072321)2.95508643
42oxidative phosphorylation (GO:0006119)2.84032565
43purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.81444889
44* protein localization to organelle (GO:0033365)2.77890659
45purine nucleoside triphosphate biosynthetic process (GO:0009145)2.77321158
46spliceosomal complex assembly (GO:0000245)2.75318569
47transcription elongation from RNA polymerase III promoter (GO:0006385)2.74397945
48termination of RNA polymerase III transcription (GO:0006386)2.74397945
49spliceosomal snRNP assembly (GO:0000387)2.69982472
50DNA strand elongation involved in DNA replication (GO:0006271)2.68002274
51telomere maintenance via semi-conservative replication (GO:0032201)2.65088365
52histone mRNA metabolic process (GO:0008334)2.64109810
53ribonucleoside triphosphate biosynthetic process (GO:0009201)2.63386984
54myeloid cell homeostasis (GO:0002262)2.59712419
55* gene expression (GO:0010467)2.58544822
56establishment of viral latency (GO:0019043)2.57268378
57GTP biosynthetic process (GO:0006183)2.56502191
58ncRNA processing (GO:0034470)2.56489649
59exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.56474089
60aerobic respiration (GO:0009060)2.55852339
61negative regulation of DNA repair (GO:0045738)2.54428665
62UTP biosynthetic process (GO:0006228)2.52938491
63nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.52581402
64DNA strand elongation (GO:0022616)2.51681914
65hydrogen ion transmembrane transport (GO:1902600)2.50284224
66DNA unwinding involved in DNA replication (GO:0006268)2.48011429
67establishment of protein localization to mitochondrial membrane (GO:0090151)2.47906466
68pseudouridine synthesis (GO:0001522)2.45605031
69termination of RNA polymerase I transcription (GO:0006363)2.40533708
70innate immune response in mucosa (GO:0002227)2.39439734
71ribonucleoprotein complex assembly (GO:0022618)2.37269659
72antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.37099774
73negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.35838176
74transcription elongation from RNA polymerase I promoter (GO:0006362)2.35577225
75termination of RNA polymerase II transcription (GO:0006369)2.34002269
76* single-organism cellular localization (GO:1902580)2.32505304
77ncRNA metabolic process (GO:0034660)2.30752034
78protein complex biogenesis (GO:0070271)2.28658465
79regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.28008066
80telomere maintenance via recombination (GO:0000722)2.27042405
81proteasome assembly (GO:0043248)2.26803494
82DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.25763716
83DNA-templated transcription, termination (GO:0006353)2.24889062
84mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.24343060
85mitochondrial respiratory chain complex I assembly (GO:0032981)2.24343060
86NADH dehydrogenase complex assembly (GO:0010257)2.24343060
87interferon-gamma secretion (GO:0072643)2.24272087
88deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.23942969
89antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.23512337
90keratinocyte proliferation (GO:0043616)2.23487918
91negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.22225932
92negative regulation of ligase activity (GO:0051352)2.22225932
93nucleoside triphosphate biosynthetic process (GO:0009142)2.22173919
94intracellular protein transmembrane import (GO:0044743)2.21870736
95signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.21790569
96intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.21790569
97ribonucleoprotein complex subunit organization (GO:0071826)2.21602668
98mitochondrial respiratory chain complex assembly (GO:0033108)2.20962289
99purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.19343053
100purine nucleoside monophosphate biosynthetic process (GO:0009127)2.19343053
101UTP metabolic process (GO:0046051)2.18558397
102regulation of protein heterodimerization activity (GO:0043497)2.17938852
103respiratory electron transport chain (GO:0022904)2.16506711
104signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.16410667
105signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.16410667
106signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.16410667
107ribosome biogenesis (GO:0042254)2.15744221
108DNA replication initiation (GO:0006270)2.15509382
109mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.15185973
110pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.14388677
111CTP metabolic process (GO:0046036)2.14180619
112CTP biosynthetic process (GO:0006241)2.14180619
113signal transduction involved in DNA integrity checkpoint (GO:0072401)2.13551785
114signal transduction involved in DNA damage checkpoint (GO:0072422)2.13551785
115lymphoid progenitor cell differentiation (GO:0002320)2.13407482
116mitotic recombination (GO:0006312)2.13145490
117electron transport chain (GO:0022900)2.12505991
118virion assembly (GO:0019068)2.11741047
119nucleotide-excision repair, DNA gap filling (GO:0006297)2.11690628
120establishment of protein localization to mitochondrion (GO:0072655)2.10919638
121antibacterial humoral response (GO:0019731)2.10666378
122positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.10608764
123mRNA splicing, via spliceosome (GO:0000398)2.10169515
124protein targeting to mitochondrion (GO:0006626)2.10117128
125regulation of translational fidelity (GO:0006450)2.09738734
126midbrain development (GO:0030901)2.09102497
127RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.08800211
128protein localization to mitochondrion (GO:0070585)2.07453977
129guanosine-containing compound biosynthetic process (GO:1901070)2.07316291
130pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.07017099
131proton transport (GO:0015992)2.05906229
132mitochondrial transport (GO:0006839)2.05465861
133RNA splicing, via transesterification reactions (GO:0000375)2.05412217
134regulation of mitochondrial translation (GO:0070129)2.05168338
135multi-organism transport (GO:0044766)2.02727791
136multi-organism localization (GO:1902579)2.02727791
137multi-organism intracellular transport (GO:1902583)2.02727791
138transport of virus (GO:0046794)2.02727791
139* viral transcription (GO:0019083)12.0480338
140* translational termination (GO:0006415)11.5440691
141ribosomal small subunit biogenesis (GO:0042274)11.1294182
142ribosomal small subunit assembly (GO:0000028)10.4835498

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1SOX9_22984422_ChIP-ChIP_TESTIS_Rat6.25353072
2* MYC_18555785_ChIP-Seq_MESCs_Mouse5.00865595
3E2F7_22180533_ChIP-Seq_HELA_Human4.98589379
4TP63_17297297_ChIP-ChIP_HaCaT_Human4.52825329
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.80724910
6* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.80564814
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.58473143
8* GABP_17652178_ChIP-ChIP_JURKAT_Human3.44184067
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.11015236
10CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.09617027
11CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.90026938
12XRN2_22483619_ChIP-Seq_HELA_Human2.87369940
13KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.83384404
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.80088785
15HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.73169664
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68093138
17CREB1_15753290_ChIP-ChIP_HEK293T_Human2.66917057
18E2F4_17652178_ChIP-ChIP_JURKAT_Human2.59284457
19TTF2_22483619_ChIP-Seq_HELA_Human2.57290472
20ELF1_17652178_ChIP-ChIP_JURKAT_Human2.50149886
21VDR_23849224_ChIP-Seq_CD4+_Human2.47569118
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.47396105
23* ELK1_19687146_ChIP-ChIP_HELA_Human2.34443686
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.32828221
25FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.29321942
26TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.18925957
27* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.18575374
28* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.11091051
29DCP1A_22483619_ChIP-Seq_HELA_Human2.05943608
30FOXM1_23109430_ChIP-Seq_U2OS_Human2.03892057
31FOXP3_21729870_ChIP-Seq_TREG_Human2.01136401
32RBPJ_22232070_ChIP-Seq_NCS_Mouse1.97210735
33NELFA_20434984_ChIP-Seq_ESCs_Mouse1.95601307
34TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.93264283
35* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.83522131
36E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.75315441
37* ELK1_22589737_ChIP-Seq_MCF10A_Human1.72016581
38MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.70961897
39NOTCH1_21737748_ChIP-Seq_TLL_Human1.62701073
40CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.62024208
41HOXB4_20404135_ChIP-ChIP_EML_Mouse1.57385460
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.55193240
43SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.55139309
44KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.54534675
45HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.53635466
46ERG_20887958_ChIP-Seq_HPC-7_Mouse1.51727805
47ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.48143723
48ESR1_15608294_ChIP-ChIP_MCF-7_Human1.47601580
49MYC_18940864_ChIP-ChIP_HL60_Human1.44403199
50NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44324608
51VDR_21846776_ChIP-Seq_THP-1_Human1.43815568
52IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.41559679
53FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.40686341
54KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.32992011
55KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.32992011
56KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.32992011
57* GABP_19822575_ChIP-Seq_HepG2_Human1.32746777
58MYC_22102868_ChIP-Seq_BL_Human1.31040676
59SPI1_23547873_ChIP-Seq_NB4_Human1.29879958
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.27434484
61BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25388096
62POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.22700565
63FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.22641514
64SCL_19346495_ChIP-Seq_HPC-7_Human1.20989018
65MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.20394472
66CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.20025550
67SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.19447187
68THAP11_20581084_ChIP-Seq_MESCs_Mouse1.18851803
69CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.17169003
70* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16737606
71CIITA_25753668_ChIP-Seq_RAJI_Human1.15981800
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.14967191
73SRF_21415370_ChIP-Seq_HL-1_Mouse1.12019813
74E2F1_21310950_ChIP-Seq_MCF-7_Human1.09578574
75AR_21909140_ChIP-Seq_LNCAP_Human1.09484949
76YY1_21170310_ChIP-Seq_MESCs_Mouse1.09235716
77MYCN_18555785_ChIP-Seq_MESCs_Mouse1.08677182
78STAT4_19710469_ChIP-ChIP_TH1__Mouse1.07379907
79NANOG_18555785_ChIP-Seq_MESCs_Mouse1.06917934
80ZNF263_19887448_ChIP-Seq_K562_Human1.04211614
81HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.03908470
82ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.02904118
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.01615071
84TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00729481
85HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.00138489
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00077104
87IRF1_19129219_ChIP-ChIP_H3396_Human0.98461019
88SRY_22984422_ChIP-ChIP_TESTIS_Rat0.98303893
89SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.98279446
90TP63_19390658_ChIP-ChIP_HaCaT_Human0.96720021
91STAT3_1855785_ChIP-Seq_MESCs_Mouse0.96256504
92TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.93894423
93KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.93801834
94MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.93676707
95KDM5A_27292631_Chip-Seq_BREAST_Human0.93141011
96SOX2_18692474_ChIP-Seq_MEFs_Mouse0.92124713
97SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.90719123
98PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89607149
99ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.88919009
100CTCF_26484167_Chip-Seq_Bcells_Mouse0.88736264
101CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.88602458
102GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87062997
103RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.86519093
104KLF4_18555785_ChIP-Seq_MESCs_Mouse0.86470057
105MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.86239605
106ELF5_23300383_ChIP-Seq_T47D_Human0.85886018
107TCF3_18692474_ChIP-Seq_MEFs_Mouse0.85868251
108MYB_26560356_Chip-Seq_TH2_Human0.85817407
109MAF_26560356_Chip-Seq_TH2_Human0.85484778
110UTX_26944678_Chip-Seq_JUKART_Human0.85031093
111CHD1_26751641_Chip-Seq_LNCaP_Human0.84579433
112IRF8_22096565_ChIP-ChIP_GC-B_Human0.84186004
113SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.83760322
114OCT4_18692474_ChIP-Seq_MEFs_Mouse0.82082650
115VDR_24763502_ChIP-Seq_THP-1_Human0.81800083
116EGR1_19374776_ChIP-ChIP_THP-1_Human0.81465558
117* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.81350212
118PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.81283208
119CTCF_18555785_ChIP-Seq_MESCs_Mouse0.80306043
120MAF_26560356_Chip-Seq_TH1_Human0.78180925
121CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.76598533

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation6.91017988
2MP0004381_abnormal_hair_follicle3.34701127
3MP0000566_synostosis2.83092466
4MP0003693_abnormal_embryo_hatching2.81015456
5MP0004957_abnormal_blastocyst_morpholog2.59580682
6MP0002796_impaired_skin_barrier2.42434263
7MP0008057_abnormal_DNA_replication2.30694612
8MP0006292_abnormal_olfactory_placode2.17401190
9MP0003941_abnormal_skin_development2.16729501
10MP0003136_yellow_coat_color2.16446519
11MP0003763_abnormal_thymus_physiology2.08965356
12MP0005174_abnormal_tail_pigmentation2.06690296
13MP0000383_abnormal_hair_follicle1.98731331
14MP0002396_abnormal_hematopoietic_system1.90343739
15MP0003077_abnormal_cell_cycle1.89390748
16MP0010094_abnormal_chromosome_stability1.89302459
17MP0005501_abnormal_skin_physiology1.84644817
18MP0002166_altered_tumor_susceptibility1.69990079
19MP0002009_preneoplasia1.66740797
20MP0000490_abnormal_crypts_of1.63509321
21MP0000465_gastrointestinal_hemorrhage1.63253576
22MP0002095_abnormal_skin_pigmentation1.60985579
23MP0001216_abnormal_epidermal_layer1.54647497
24MP0000685_abnormal_immune_system1.53153109
25MP0009333_abnormal_splenocyte_physiolog1.51794393
26MP0002060_abnormal_skin_morphology1.50484204
27MP0005409_darkened_coat_color1.48759066
28MP0001835_abnormal_antigen_presentation1.47598312
29MP0005075_abnormal_melanosome_morpholog1.47194512
30MP0003786_premature_aging1.45722713
31MP0001800_abnormal_humoral_immune1.45212605
32MP0010678_abnormal_skin_adnexa1.44988149
33MP0003111_abnormal_nucleus_morphology1.44723085
34MP0002132_abnormal_respiratory_system1.44552235
35MP0002098_abnormal_vibrissa_morphology1.43339140
36MP0008932_abnormal_embryonic_tissue1.41040331
37MP0006054_spinal_hemorrhage1.39301988
38MP0002006_tumorigenesis1.37966521
39MP0005671_abnormal_response_to1.34888762
40MP0002148_abnormal_hypersensitivity_rea1.33659093
41MP0001853_heart_inflammation1.33657652
42MP0002398_abnormal_bone_marrow1.31733253
43MP0004808_abnormal_hematopoietic_stem1.31381925
44MP0008007_abnormal_cellular_replicative1.30776281
45MP0002938_white_spotting1.29036338
46MP0000372_irregular_coat_pigmentation1.27821418
47MP0000703_abnormal_thymus_morphology1.26514012
48MP0001286_abnormal_eye_development1.26116107
49MP0002420_abnormal_adaptive_immunity1.25073063
50MP0001293_anophthalmia1.24884648
51MP0005000_abnormal_immune_tolerance1.24757116
52MP0002722_abnormal_immune_system1.24293011
53MP0003186_abnormal_redox_activity1.24044951
54MP0003453_abnormal_keratinocyte_physiol1.23834713
55MP0003806_abnormal_nucleotide_metabolis1.21356303
56MP0002452_abnormal_antigen_presenting1.21267652
57MP0001819_abnormal_immune_cell1.21132535
58MP0002723_abnormal_immune_serum1.19391059
59MP0010352_gastrointestinal_tract_polyps1.17911626
60MP0010771_integument_phenotype1.17801816
61MP0000377_abnormal_hair_follicle1.17447692
62MP0003436_decreased_susceptibility_to1.17162322
63MP0005025_abnormal_response_to1.15436064
64MP0008961_abnormal_basal_metabolism1.13708364
65MP0008058_abnormal_DNA_repair1.13407989
66MP0009785_altered_susceptibility_to1.12847311
67MP0004947_skin_inflammation1.12125623
68MP0002102_abnormal_ear_morphology1.11596538
69MP0001873_stomach_inflammation1.11572124
70MP0002254_reproductive_system_inflammat1.11442981
71MP0000647_abnormal_sebaceous_gland1.09821656
72MP0010234_abnormal_vibrissa_follicle1.09314965
73MP0002163_abnormal_gland_morphology1.09296112
74MP0000689_abnormal_spleen_morphology1.08804511
75MP0002277_abnormal_respiratory_mucosa1.08350883
76MP0000716_abnormal_immune_system1.07917285
77MP0002405_respiratory_system_inflammati1.06539541
78MP0002697_abnormal_eye_size1.05831667
79MP0003890_abnormal_embryonic-extraembry1.05597901
80MP0001346_abnormal_lacrimal_gland1.05568855
81MP0010155_abnormal_intestine_physiology1.02882281
82MP0002429_abnormal_blood_cell1.02855932
83MP0001851_eye_inflammation1.02713554
84MP0005397_hematopoietic_system_phenotyp1.01653682
85MP0001545_abnormal_hematopoietic_system1.01653682
86MP0004185_abnormal_adipocyte_glucose1.00124920
87MP0003567_abnormal_fetal_cardiomyocyte0.99993926
88MP0003315_abnormal_perineum_morphology0.99515428
89MP0000762_abnormal_tongue_morphology0.98417784
90MP0005387_immune_system_phenotype0.96130724
91MP0001790_abnormal_immune_system0.96130724
92MP0008995_early_reproductive_senescence0.94222335
93MP0009931_abnormal_skin_appearance0.93479024
94MP0003123_paternal_imprinting0.92964404
95MP0002019_abnormal_tumor_incidence0.92535182
96MP0001881_abnormal_mammary_gland0.92260066
97MP0000350_abnormal_cell_proliferation0.91658596
98MP0002282_abnormal_trachea_morphology0.91030333
99MP0004142_abnormal_muscle_tone0.90374718
100MP0010030_abnormal_orbit_morphology0.90249860
101MP0005408_hypopigmentation0.90021693
102MP0000631_abnormal_neuroendocrine_gland0.89779031
103MP0002249_abnormal_larynx_morphology0.89423281
104MP0001919_abnormal_reproductive_system0.89384308
105MP0002210_abnormal_sex_determination0.87733142
106MP0003866_abnormal_defecation0.87326823
107MP0000467_abnormal_esophagus_morphology0.86143056
108MP0005275_abnormal_skin_tensile0.85904135
109MP0003724_increased_susceptibility_to0.85566740
110MP0004264_abnormal_extraembryonic_tissu0.84972178
111MP0003959_abnormal_lean_body0.82640318
112MP0000858_altered_metastatic_potential0.82438107
113MP0001243_abnormal_dermal_layer0.81993203
114MP0003938_abnormal_ear_development0.81496912
115MP0001191_abnormal_skin_condition0.81172537
116MP0001340_abnormal_eyelid_morphology0.80847994
117MP0001697_abnormal_embryo_size0.79976490
118MP0000537_abnormal_urethra_morphology0.78130153
119MP0000627_abnormal_mammary_gland0.76996677
120MP0002085_abnormal_embryonic_tissue0.75784179
121MP0003984_embryonic_growth_retardation0.75728777
122MP0002088_abnormal_embryonic_growth/wei0.75601721
123MP0005023_abnormal_wound_healing0.74553517
124MP0001672_abnormal_embryogenesis/_devel0.73291625
125MP0005380_embryogenesis_phenotype0.73291625
126MP0008789_abnormal_olfactory_epithelium0.71744719
127MP0000313_abnormal_cell_death0.70947702
128MP0003638_abnormal_response/metabolism_0.69427663
129MP0002653_abnormal_ependyma_morphology0.69242361
130MP0003283_abnormal_digestive_organ0.69064391
131MP0001145_abnormal_male_reproductive0.68661070
132MP0003011_delayed_dark_adaptation0.68535322
133MP0009053_abnormal_anal_canal0.68241196
134MP0002092_abnormal_eye_morphology0.67225614
135MP0003936_abnormal_reproductive_system0.66696523
136MP0001529_abnormal_vocalization0.66656240
137MP0006035_abnormal_mitochondrial_morpho0.64060432
138MP0002160_abnormal_reproductive_system0.62792023
139MP0002751_abnormal_autonomic_nervous0.59260570

Predicted human phenotypes

RankGene SetZ-score
1Abnormal number of erythroid precursors (HP:0012131)9.57412208
2Reticulocytopenia (HP:0001896)9.24493616
3Macrocytic anemia (HP:0001972)7.19675195
4Pallor (HP:0000980)6.75405614
5Abnormal hemoglobin (HP:0011902)4.22677058
6Congenital, generalized hypertrichosis (HP:0004540)3.61254670
7Thrombocytosis (HP:0001894)3.39397928
8Colon cancer (HP:0003003)3.26530376
9Aplasia/Hypoplasia of the sacrum (HP:0008517)3.24756032
10Depressed nasal ridge (HP:0000457)3.12755036
11Stenosis of the external auditory canal (HP:0000402)3.08248235
12Increased hepatocellular lipid droplets (HP:0006565)3.04617356
1311 pairs of ribs (HP:0000878)3.03017272
14Abnormality of the axillary hair (HP:0100134)3.00350542
15Abnormality of secondary sexual hair (HP:0009888)3.00350542
16Parakeratosis (HP:0001036)2.89732734
17Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.85584631
18Woolly hair (HP:0002224)2.83666866
19Abnormality of reticulocytes (HP:0004312)2.83573864
20Increased muscle lipid content (HP:0009058)2.71844072
21Migraine (HP:0002076)2.71609608
22Septo-optic dysplasia (HP:0100842)2.70728773
23Aplastic anemia (HP:0001915)2.67925263
24Acute necrotizing encephalopathy (HP:0006965)2.66752172
25Absent thumb (HP:0009777)2.61230621
26Mitochondrial inheritance (HP:0001427)2.56527426
27Exertional dyspnea (HP:0002875)2.51409592
28Thick lower lip vermilion (HP:0000179)2.50740902
29Lipid accumulation in hepatocytes (HP:0006561)2.50480906
30Chronic otitis media (HP:0000389)2.49964754
31IgM deficiency (HP:0002850)2.46308799
32Asplenia (HP:0001746)2.44271210
33Cerebral edema (HP:0002181)2.43460038
34Fragile nails (HP:0001808)2.39905502
35Trismus (HP:0000211)2.39816597
36Respiratory difficulties (HP:0002880)2.39309151
37Partial duplication of thumb phalanx (HP:0009944)2.39275746
38Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.36474779
39Renal Fanconi syndrome (HP:0001994)2.34876088
40Aplasia/Hypoplasia of the spleen (HP:0010451)2.28268826
41Maternal diabetes (HP:0009800)2.27980245
42Abnormality of renal resorption (HP:0011038)2.27445430
43Partial duplication of the phalanx of hand (HP:0009999)2.27276537
44Abnormal mitochondria in muscle tissue (HP:0008316)2.23634706
45Decreased activity of mitochondrial respiratory chain (HP:0008972)2.22748243
46Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.22748243
47Congenital ichthyosiform erythroderma (HP:0007431)2.22585875
48Nasolacrimal duct obstruction (HP:0000579)2.20441993
49Hypotrichosis (HP:0001006)2.19667141
50Concave nail (HP:0001598)2.19404232
51Microvesicular hepatic steatosis (HP:0001414)2.17188396
52Progressive macrocephaly (HP:0004481)2.16371341
53Hyperphosphaturia (HP:0003109)2.15792435
54Absent septum pellucidum (HP:0001331)2.08783036
55Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.07488630
56Hypoplasia of the radius (HP:0002984)2.06435133
57Elevated erythrocyte sedimentation rate (HP:0003565)2.05694267
58Multiple enchondromatosis (HP:0005701)2.04902548
59Lip pit (HP:0100267)2.02940163
60Hypoproteinemia (HP:0003075)2.02152959
61Abnormality of the septum pellucidum (HP:0007375)2.01536092
62Leukodystrophy (HP:0002415)2.01421636
63Triphalangeal thumb (HP:0001199)2.01018416
64Aplasia cutis congenita (HP:0001057)2.00664215
65Glossoptosis (HP:0000162)2.00476222
66Sparse eyelashes (HP:0000653)2.00447637
67Abnormality of cells of the erythroid lineage (HP:0012130)10.7787104
68Increased CSF lactate (HP:0002490)1.99956710
69Hepatocellular necrosis (HP:0001404)1.96694076
703-Methylglutaconic aciduria (HP:0003535)1.93657476
71Abnormality of the lacrimal duct (HP:0011481)1.92577761
72Septate vagina (HP:0001153)1.91987086
73Bilateral microphthalmos (HP:0007633)1.90681411
74Increased intramyocellular lipid droplets (HP:0012240)1.87532003
75Supernumerary ribs (HP:0005815)1.86746113
76Erythema (HP:0010783)1.86182192
77Abnormal urine phosphate concentration (HP:0012599)1.85218996
78Oral leukoplakia (HP:0002745)1.83732010
79Lactic acidosis (HP:0003128)1.83723655
80Rib fusion (HP:0000902)1.83336952
81Poikiloderma (HP:0001029)1.82780875
82Recurrent bronchitis (HP:0002837)1.81210279
83Petechiae (HP:0000967)1.81064013
84Optic disc pallor (HP:0000543)1.81051845
85Acute encephalopathy (HP:0006846)1.79968971
86Anhidrosis (HP:0000970)1.77469528
87Onycholysis (HP:0001806)1.77060077
88Pancytopenia (HP:0001876)1.74486633
89Abnormality of the nasolacrimal system (HP:0000614)1.73568199
90Rough bone trabeculation (HP:0100670)1.72368805
91Respiratory failure (HP:0002878)1.69791113
92Panhypogammaglobulinemia (HP:0003139)1.68168437
93Supernumerary bones of the axial skeleton (HP:0009144)1.68158438
94Aplasia/Hypoplasia of the thymus (HP:0010515)1.66326861
95Increased serum lactate (HP:0002151)1.64759881
96Abnormality of the heme biosynthetic pathway (HP:0010472)1.63854637
97Cleft eyelid (HP:0000625)1.61141141
98Birth length less than 3rd percentile (HP:0003561)1.61031503
99Duplication of thumb phalanx (HP:0009942)1.60882705
100Sparse scalp hair (HP:0002209)1.60633951
101Ridged nail (HP:0001807)1.60558729
102Villous atrophy (HP:0011473)1.59581161
103Abnormality of small intestinal villus morphology (HP:0011472)1.59581161
104Cellular immunodeficiency (HP:0005374)1.58671353
105Myelodysplasia (HP:0002863)1.58172069
106Sparse lateral eyebrow (HP:0005338)1.57959897
107Seborrheic dermatitis (HP:0001051)1.57955301
108Abnormality of the pons (HP:0007361)1.57859004
109Short nose (HP:0003196)1.57833990
110Missing ribs (HP:0000921)1.56954330
111Esophageal atresia (HP:0002032)1.56819710
112Chromosomal breakage induced by crosslinking agents (HP:0003221)1.56367377
113Acute lymphatic leukemia (HP:0006721)1.55851411
114Plantar hyperkeratosis (HP:0007556)1.55423946
115Atresia of the external auditory canal (HP:0000413)1.55421192
116Hypoparathyroidism (HP:0000829)1.55212894
117Hypoplasia of the pons (HP:0012110)1.55207044
118Premature graying of hair (HP:0002216)1.54414484
119Entropion (HP:0000621)1.54364498
120Colitis (HP:0002583)1.53676308
121IgG deficiency (HP:0004315)1.52148063
122Degeneration of anterior horn cells (HP:0002398)1.50883928
123Abnormality of the anterior horn cell (HP:0006802)1.50883928
124Hepatic necrosis (HP:0002605)1.50164031
125Sex reversal (HP:0012245)1.49551242
126Abnormal sex determination (HP:0012244)1.49551242
127Renal tubular dysfunction (HP:0000124)1.48678360
128Nail dystrophy (HP:0008404)1.47237126
129Exercise intolerance (HP:0003546)1.46988112
130Abnormality of the preputium (HP:0100587)1.46949883
131Lymphoma (HP:0002665)1.46693118
132Abnormality of the parietal bone (HP:0002696)1.46178747
133Conical tooth (HP:0000698)1.45566235
134Chromsome breakage (HP:0040012)1.45521664
135Basal cell carcinoma (HP:0002671)1.45341863
136Prolonged bleeding time (HP:0003010)1.45260403
137Forearm undergrowth (HP:0009821)1.44724471
138Increased IgE level (HP:0003212)1.44603324
139Pili torti (HP:0003777)1.44264998
140Selective tooth agenesis (HP:0001592)1.43344113
141Type I transferrin isoform profile (HP:0003642)1.42996388
142Abnormality of the phalanges of the 2nd finger (HP:0009541)1.42909911

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME25.56725015
2VRK24.64867789
3MST43.05856270
4LRRK22.95320503
5RPS6KB22.82251167
6WEE12.73244865
7TLK12.56955345
8BUB12.42780031
9VRK12.39739592
10TGFBR12.23670101
11EEF2K2.22084938
12STK162.18233365
13MAP4K12.17651248
14PIM22.17498748
15DYRK32.13320281
16SIK12.12307914
17SRPK11.90242880
18TRIB31.86309975
19CDK191.78604470
20PASK1.70725807
21PRPF4B1.69579285
22MAP3K121.61863115
23PNCK1.61002818
24TAF11.59354703
25MKNK11.55803282
26MAP3K31.52393290
27MAPKAPK31.48586084
28MST1R1.47097720
29SMG11.43125824
30BTK1.34636887
31TEC1.33175715
32EIF2AK31.32645205
33RPS6KA41.32347317
34STK101.30587590
35AURKB1.29392678
36BRSK21.27211661
37SCYL21.23877594
38ILK1.21031255
39CDC71.19596753
40NME11.12778214
41CDK71.11100905
42MARK31.11003593
43MAPKAPK51.10647168
44MAP3K101.07179635
45RPS6KA51.02386124
46TYK21.01954340
47IKBKB1.00860462
48KIT1.00763890
49NLK0.99770799
50KDR0.98018511
51BLK0.97627709
52GRK60.96760453
53EIF2AK10.92919253
54ACVR1B0.91142706
55PIM10.88294573
56BMPR1B0.88154142
57FLT30.87903086
58SYK0.87713428
59ITK0.82471806
60NEK20.80897551
61TESK20.80534147
62CSNK2A20.79925119
63PBK0.78214453
64FGFR20.75552216
65EPHB20.73872066
66MAP2K30.73766235
67PTK60.72691581
68CDK80.72179985
69EIF2AK20.71993683
70CLK10.69168557
71LCK0.68931912
72TYRO30.68817562
73CSF1R0.67593759
74TNIK0.65946657
75AURKA0.64314214
76MAP3K130.64150727
77TSSK60.63826542
78TXK0.62164414
79PIK3CA0.61522161
80MKNK20.61269027
81PAK20.61097322
82GRK70.61057776
83ZAP700.61042809
84PLK10.60928780
85TGFBR20.60836142
86LYN0.59155711
87JAK30.58945469
88CSNK2A10.58680403
89IRAK20.57780427
90MAP2K20.57494483
91ATR0.57094392
92DYRK1B0.56624612
93CDK40.55668909
94RPS6KC10.55088888
95RPS6KL10.55088888
96CDK30.55051117
97CHUK0.55014430
98BMPR20.51663591
99MAPK40.51565366
100RPS6KA60.51486505
101PKN20.51072940
102RIPK40.51049263
103IRAK40.50807347
104DYRK20.50474652
105IKBKE0.50380467
106MAP3K80.49945327
107SIK30.48803729
108TRPM70.48759441
109DAPK30.48513884
110PIK3CG0.48082478
111CDK60.47969188
112MUSK0.47338653
113YES10.46970514
114NEK10.46822744
115MELK0.46822092
116MAPKAPK20.46127785
117PAK40.45309314
118GRK10.44907181
119STK40.44095922
120NEK60.42661041
121TAOK30.42417580
122ZAK0.42181543
123MAPK150.41562521
124STK240.40390102
125EPHA20.38416442
126TBK10.37722118
127ADRBK10.37268681
128TTK0.36799732
129RPS6KA10.36486824
130CCNB10.36270476
131PAK10.34675087
132CHEK20.33779705
133HIPK20.33603590
134CHEK10.33230939
135FES0.31729559

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030109.22205240
2RNA polymerase_Homo sapiens_hsa030203.01515976
3DNA replication_Homo sapiens_hsa030302.96700695
4Proteasome_Homo sapiens_hsa030502.92011898
5Spliceosome_Homo sapiens_hsa030402.79883699
6Mismatch repair_Homo sapiens_hsa034302.53597969
7Oxidative phosphorylation_Homo sapiens_hsa001902.31358654
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.16424744
9Parkinsons disease_Homo sapiens_hsa050122.09101629
10Protein export_Homo sapiens_hsa030602.07951048
11Pyrimidine metabolism_Homo sapiens_hsa002401.94389947
12Nucleotide excision repair_Homo sapiens_hsa034201.93989527
13Homologous recombination_Homo sapiens_hsa034401.92002001
14RNA transport_Homo sapiens_hsa030131.73096832
15Base excision repair_Homo sapiens_hsa034101.60820436
16Primary immunodeficiency_Homo sapiens_hsa053401.59651007
17Huntingtons disease_Homo sapiens_hsa050161.58773899
18Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.53417509
19Alzheimers disease_Homo sapiens_hsa050101.50085621
20Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.43562794
21Non-homologous end-joining_Homo sapiens_hsa034501.37231519
22RNA degradation_Homo sapiens_hsa030181.35798267
23Systemic lupus erythematosus_Homo sapiens_hsa053221.35332666
24Cyanoamino acid metabolism_Homo sapiens_hsa004601.35184246
25p53 signaling pathway_Homo sapiens_hsa041151.18868745
26Fanconi anemia pathway_Homo sapiens_hsa034601.15713378
27Basal transcription factors_Homo sapiens_hsa030221.12832153
28Cell cycle_Homo sapiens_hsa041101.10097329
29One carbon pool by folate_Homo sapiens_hsa006701.03579538
30Hematopoietic cell lineage_Homo sapiens_hsa046401.01468507
31Antigen processing and presentation_Homo sapiens_hsa046120.99869994
32Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.99178111
33Epstein-Barr virus infection_Homo sapiens_hsa051690.92063022
34Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.91268807
35Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.88425574
36Purine metabolism_Homo sapiens_hsa002300.86033093
37Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.83548769
38Herpes simplex infection_Homo sapiens_hsa051680.82839175
39Transcriptional misregulation in cancer_Homo sapiens_hsa052020.81073034
40mRNA surveillance pathway_Homo sapiens_hsa030150.68460579
41Intestinal immune network for IgA production_Homo sapiens_hsa046720.66647123
42NF-kappa B signaling pathway_Homo sapiens_hsa040640.65076846
43Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.63722767
44Arachidonic acid metabolism_Homo sapiens_hsa005900.63443559
45Viral carcinogenesis_Homo sapiens_hsa052030.62946675
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.59198287
47Asthma_Homo sapiens_hsa053100.58963557
48HTLV-I infection_Homo sapiens_hsa051660.58490852
49Glutathione metabolism_Homo sapiens_hsa004800.57872900
50Allograft rejection_Homo sapiens_hsa053300.57338295
51Measles_Homo sapiens_hsa051620.56466084
52Alcoholism_Homo sapiens_hsa050340.55169227
53Jak-STAT signaling pathway_Homo sapiens_hsa046300.53141984
54Small cell lung cancer_Homo sapiens_hsa052220.52388695
55Basal cell carcinoma_Homo sapiens_hsa052170.51966758
56Sulfur relay system_Homo sapiens_hsa041220.50849772
57T cell receptor signaling pathway_Homo sapiens_hsa046600.50646049
58B cell receptor signaling pathway_Homo sapiens_hsa046620.49967171
59Graft-versus-host disease_Homo sapiens_hsa053320.48979834
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48869689
61Sphingolipid metabolism_Homo sapiens_hsa006000.48361772
62Colorectal cancer_Homo sapiens_hsa052100.47372273
63Folate biosynthesis_Homo sapiens_hsa007900.46941341
64Type I diabetes mellitus_Homo sapiens_hsa049400.46758531
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.44890728
66Linoleic acid metabolism_Homo sapiens_hsa005910.43398639
67Apoptosis_Homo sapiens_hsa042100.39686985
68Non-small cell lung cancer_Homo sapiens_hsa052230.39497487
69Cardiac muscle contraction_Homo sapiens_hsa042600.39398918
70Maturity onset diabetes of the young_Homo sapiens_hsa049500.39291142
71Legionellosis_Homo sapiens_hsa051340.37411496
72Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.37337927
73Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37280679
74MicroRNAs in cancer_Homo sapiens_hsa052060.37078730
75Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.36603229
76Chronic myeloid leukemia_Homo sapiens_hsa052200.36516742
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.36451870
78Autoimmune thyroid disease_Homo sapiens_hsa053200.36207836
79Notch signaling pathway_Homo sapiens_hsa043300.35651140
80Prostate cancer_Homo sapiens_hsa052150.35015185
81N-Glycan biosynthesis_Homo sapiens_hsa005100.34971354
82Renal cell carcinoma_Homo sapiens_hsa052110.33486895
83Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.33399621
84Hepatitis B_Homo sapiens_hsa051610.33077197
85RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.32803512
86Shigellosis_Homo sapiens_hsa051310.32697565
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.32576262
88Pathways in cancer_Homo sapiens_hsa052000.32083669
89Leishmaniasis_Homo sapiens_hsa051400.31876811
90Platelet activation_Homo sapiens_hsa046110.31628888
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.30851041
92Wnt signaling pathway_Homo sapiens_hsa043100.30692526
93Vitamin digestion and absorption_Homo sapiens_hsa049770.28387180
94Malaria_Homo sapiens_hsa051440.27477880
95Thyroid cancer_Homo sapiens_hsa052160.27284883
96Ether lipid metabolism_Homo sapiens_hsa005650.25820024
97TGF-beta signaling pathway_Homo sapiens_hsa043500.25684227
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.24939910
99Toxoplasmosis_Homo sapiens_hsa051450.24885661
100Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.24717771
101Viral myocarditis_Homo sapiens_hsa054160.24505850
102Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.24412233
103Pancreatic cancer_Homo sapiens_hsa052120.23924161
104Influenza A_Homo sapiens_hsa051640.23667676
105Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.23174316
106Osteoclast differentiation_Homo sapiens_hsa043800.22616855
107Pertussis_Homo sapiens_hsa051330.22466939
108Hedgehog signaling pathway_Homo sapiens_hsa043400.21988952
109Endometrial cancer_Homo sapiens_hsa052130.21692391
110Acute myeloid leukemia_Homo sapiens_hsa052210.21666491
111Metabolic pathways_Homo sapiens_hsa011000.21278547
112Fatty acid elongation_Homo sapiens_hsa000620.21093907
113alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.20722646
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.20429197
115ECM-receptor interaction_Homo sapiens_hsa045120.20393497
116Pentose phosphate pathway_Homo sapiens_hsa000300.18694620
117Pyruvate metabolism_Homo sapiens_hsa006200.18167465
118Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.17720193
119HIF-1 signaling pathway_Homo sapiens_hsa040660.13676201
120Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.13169475
121Cysteine and methionine metabolism_Homo sapiens_hsa002700.12790445
122Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.09781317
123Tyrosine metabolism_Homo sapiens_hsa003500.08476539
124Bladder cancer_Homo sapiens_hsa052190.08017588
125Biosynthesis of amino acids_Homo sapiens_hsa012300.08016308
126Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.06862420

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