RPL30P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1phenylpropanoid metabolic process (GO:0009698)7.74956903
2behavioral response to nicotine (GO:0035095)6.32914753
3pyrimidine nucleobase catabolic process (GO:0006208)5.18038032
4energy coupled proton transport, down electrochemical gradient (GO:0015985)5.02246499
5ATP synthesis coupled proton transport (GO:0015986)5.02246499
6viral transcription (GO:0019083)4.98659845
7ribosomal small subunit assembly (GO:0000028)4.83526367
8translational termination (GO:0006415)4.73258001
9xenobiotic catabolic process (GO:0042178)4.63887764
10mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.63234511
11ribosomal small subunit biogenesis (GO:0042274)4.51395935
12alkaloid metabolic process (GO:0009820)4.51040348
13glyoxylate metabolic process (GO:0046487)4.34787533
14oxidative demethylation (GO:0070989)4.34717942
15nucleobase catabolic process (GO:0046113)4.21685064
16translational elongation (GO:0006414)4.06761954
17SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.99658078
18cotranslational protein targeting to membrane (GO:0006613)3.96452338
19rRNA catabolic process (GO:0016075)3.96383453
20protein targeting to ER (GO:0045047)3.95238586
21positive regulation of oligodendrocyte differentiation (GO:0048714)3.89750125
22serine family amino acid catabolic process (GO:0009071)3.86439569
23mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.83733341
24mitochondrial respiratory chain complex I assembly (GO:0032981)3.83733341
25NADH dehydrogenase complex assembly (GO:0010257)3.83733341
26protein complex biogenesis (GO:0070271)3.78644037
27establishment of protein localization to endoplasmic reticulum (GO:0072599)3.76675956
28somite development (GO:0061053)3.70130669
29protein localization to endoplasmic reticulum (GO:0070972)3.67914844
30viral life cycle (GO:0019058)3.58721487
31establishment of protein localization to mitochondrial membrane (GO:0090151)3.56370165
32axonal fasciculation (GO:0007413)3.53679834
33limb development (GO:0060173)3.53068035
34appendage development (GO:0048736)3.53068035
35chaperone-mediated protein transport (GO:0072321)3.47241398
36cellular protein complex disassembly (GO:0043624)3.45540915
37mitochondrial respiratory chain complex assembly (GO:0033108)3.44221584
38nonmotile primary cilium assembly (GO:0035058)3.34086989
39ribosomal large subunit biogenesis (GO:0042273)3.31233492
40regulation of microtubule-based movement (GO:0060632)3.29957987
41thalamus development (GO:0021794)3.27397941
42nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.25610633
43hypothalamus development (GO:0021854)3.25475484
44positive regulation of vascular permeability (GO:0043117)3.25398782
45negative regulation of response to food (GO:0032096)3.21408517
46negative regulation of appetite (GO:0032099)3.21408517
47positive regulation of growth hormone secretion (GO:0060124)3.19903841
48growth hormone secretion (GO:0030252)3.18575564
49cytokine biosynthetic process (GO:0042089)3.17198161
50pyrimidine dimer repair (GO:0006290)3.16696578
51synaptic transmission, cholinergic (GO:0007271)3.12650159
52sulfur amino acid catabolic process (GO:0000098)3.11496435
53translational initiation (GO:0006413)3.08843514
54retinal cone cell development (GO:0046549)3.02615573
55ubiquinone biosynthetic process (GO:0006744)3.00840513
56regulation of collateral sprouting (GO:0048670)2.99537661
57protein neddylation (GO:0045116)2.97159223
58spinal cord association neuron differentiation (GO:0021527)2.92287321
59ATP biosynthetic process (GO:0006754)2.91391303
60ncRNA catabolic process (GO:0034661)2.91174352
61drug catabolic process (GO:0042737)2.89949461
62protein complex disassembly (GO:0043241)2.88628067
63catecholamine biosynthetic process (GO:0042423)2.88262146
64catechol-containing compound biosynthetic process (GO:0009713)2.88262146
65response to misfolded protein (GO:0051788)2.86067987
66water-soluble vitamin biosynthetic process (GO:0042364)2.85645513
67sequestering of actin monomers (GO:0042989)2.85006493
68electron transport chain (GO:0022900)2.83633839
69glycerophospholipid catabolic process (GO:0046475)2.81859180
70regulation of growth hormone secretion (GO:0060123)2.80394113
71purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.79214203
72respiratory electron transport chain (GO:0022904)2.78878686
73substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.78287591
74substrate-independent telencephalic tangential migration (GO:0021826)2.78287591
75macromolecular complex disassembly (GO:0032984)2.77003085
76pattern specification involved in kidney development (GO:0061004)2.74776221
77cell differentiation in spinal cord (GO:0021515)2.74109437
78regulation of cilium movement (GO:0003352)2.73283003
79pharyngeal system development (GO:0060037)2.72849990
80ubiquinone metabolic process (GO:0006743)2.71477481
81serine family amino acid metabolic process (GO:0009069)2.69701059
82detection of light stimulus involved in sensory perception (GO:0050962)2.68967103
83detection of light stimulus involved in visual perception (GO:0050908)2.68967103
84protein targeting to membrane (GO:0006612)2.68721770
85purine nucleoside triphosphate biosynthetic process (GO:0009145)2.67634696
86mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.66545636
87peptidyl-histidine modification (GO:0018202)2.66045667
88base-excision repair, AP site formation (GO:0006285)2.65128855
89spinal cord motor neuron differentiation (GO:0021522)2.64080062
90regulation of appetite (GO:0032098)2.63691547
91telomere maintenance via telomerase (GO:0007004)2.63388281
92negative regulation of telomere maintenance (GO:0032205)2.61590402
93glycine metabolic process (GO:0006544)2.61571251
94hydrogen ion transmembrane transport (GO:1902600)2.61098291
95translation (GO:0006412)2.60940938
96epoxygenase P450 pathway (GO:0019373)2.59568311
97positive regulation of gastrulation (GO:2000543)2.57681969
98auditory receptor cell differentiation (GO:0042491)2.56785099
99cellular response to cholesterol (GO:0071397)2.55738363
100cytokine metabolic process (GO:0042107)2.54895830

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.57681626
2VDR_22108803_ChIP-Seq_LS180_Human3.86757215
3HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.68789838
4EST1_17652178_ChIP-ChIP_JURKAT_Human2.50368599
5ZNF274_21170338_ChIP-Seq_K562_Hela2.50102023
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.36402339
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.33003473
8GABP_17652178_ChIP-ChIP_JURKAT_Human2.31629552
9NOTCH1_21737748_ChIP-Seq_TLL_Human2.30254927
10SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.28500299
11IGF1R_20145208_ChIP-Seq_DFB_Human2.08745406
12IRF1_19129219_ChIP-ChIP_H3396_Human2.06274306
13CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.02257079
14KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.97671094
15ELF1_17652178_ChIP-ChIP_JURKAT_Human1.75969933
16ETS1_20019798_ChIP-Seq_JURKAT_Human1.75221533
17ELK1_19687146_ChIP-ChIP_HELA_Human1.74645037
18YY1_21170310_ChIP-Seq_MESCs_Mouse1.69552812
19MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.68312273
20GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.67977033
21EZH2_27294783_Chip-Seq_ESCs_Mouse1.65022000
22EED_16625203_ChIP-ChIP_MESCs_Mouse1.62622894
23JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.61479628
24CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60868332
25MYC_18940864_ChIP-ChIP_HL60_Human1.60696056
26TP53_22573176_ChIP-Seq_HFKS_Human1.54926726
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.53412412
28GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.51856607
29CBX2_27304074_Chip-Seq_ESCs_Mouse1.51332442
30PCGF2_27294783_Chip-Seq_NPCs_Mouse1.47562966
31ER_23166858_ChIP-Seq_MCF-7_Human1.47351916
32EZH2_27304074_Chip-Seq_ESCs_Mouse1.44749016
33HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43056818
34REST_21632747_ChIP-Seq_MESCs_Mouse1.40075290
35P300_19829295_ChIP-Seq_ESCs_Human1.39600347
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.39492491
37GBX2_23144817_ChIP-Seq_PC3_Human1.37716961
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.37167409
39KLF5_20875108_ChIP-Seq_MESCs_Mouse1.34868685
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.33042209
41EGR1_23403033_ChIP-Seq_LIVER_Mouse1.32583550
42NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.32268842
43SUZ12_27294783_Chip-Seq_ESCs_Mouse1.31559766
44VDR_23849224_ChIP-Seq_CD4+_Human1.27273614
45TAF2_19829295_ChIP-Seq_ESCs_Human1.26997194
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26528290
47POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.26528290
48SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.26260903
49BCAT_22108803_ChIP-Seq_LS180_Human1.26107812
50GATA3_21878914_ChIP-Seq_MCF-7_Human1.24016234
51JARID2_20064375_ChIP-Seq_MESCs_Mouse1.23780366
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.22825363
53EWS_26573619_Chip-Seq_HEK293_Human1.21704021
54PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.21155130
55TDRD3_21172665_ChIP-Seq_MCF-7_Human1.20782818
56SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.20712429
57ETV2_25802403_ChIP-Seq_MESCs_Mouse1.20382676
58SOX2_18555785_ChIP-Seq_MESCs_Mouse1.18647713
59REST_18959480_ChIP-ChIP_MESCs_Mouse1.17104866
60CBP_20019798_ChIP-Seq_JUKART_Human1.15992607
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15992607
62PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.14896437
63FLI1_27457419_Chip-Seq_LIVER_Mouse1.13809353
64RNF2_18974828_ChIP-Seq_MESCs_Mouse1.12797000
65EZH2_18974828_ChIP-Seq_MESCs_Mouse1.12797000
66FOXH1_21741376_ChIP-Seq_EPCs_Human1.09915566
67FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.09858398
68PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.09019567
69POU5F1_16153702_ChIP-ChIP_HESCs_Human1.08707100
70PCGF2_27294783_Chip-Seq_ESCs_Mouse1.08667702
71SUZ12_27294783_Chip-Seq_NPCs_Mouse1.08274739
72AUTS2_25519132_ChIP-Seq_293T-REX_Human1.07656100
73NANOG_19829295_ChIP-Seq_ESCs_Human1.04891595
74SOX2_19829295_ChIP-Seq_ESCs_Human1.04891595
75UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.04583467
76RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.04534683
77AR_20517297_ChIP-Seq_VCAP_Human1.03756553
78ERG_20517297_ChIP-Seq_VCAP_Human1.03641419
79P53_21459846_ChIP-Seq_SAOS-2_Human1.01777626
80TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.01508904
81NCOR_22424771_ChIP-Seq_293T_Human1.00775307
82CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.00732148
83EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99565290
84NFE2_27457419_Chip-Seq_LIVER_Mouse0.98700572
85TOP2B_26459242_ChIP-Seq_MCF-7_Human0.96905359
86TTF2_22483619_ChIP-Seq_HELA_Human0.96796371
87NANOG_20526341_ChIP-Seq_ESCs_Human0.95411734
88MYC_19829295_ChIP-Seq_ESCs_Human0.95135533
89CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.94590289
90SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.94261719
91CEBPA_26348894_ChIP-Seq_LIVER_Mouse0.94190556
92POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93934477
93SOX2_16153702_ChIP-ChIP_HESCs_Human0.93561843
94SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.90964110
95CREB1_15753290_ChIP-ChIP_HEK293T_Human0.88729297
96HOXB7_26014856_ChIP-Seq_BT474_Human0.88641463
97EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88620246
98MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.88486700
99FOXP3_21729870_ChIP-Seq_TREG_Human0.88177707
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.87725740

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003787_abnormal_imprinting4.09824922
2MP0001348_abnormal_lacrimal_gland3.94780453
3MP0009379_abnormal_foot_pigmentation3.37133979
4MP0002138_abnormal_hepatobiliary_system3.27746519
5MP0010030_abnormal_orbit_morphology2.59786904
6MP0008877_abnormal_DNA_methylation2.56527261
7MP0008789_abnormal_olfactory_epithelium2.54668603
8MP0001502_abnormal_circadian_rhythm2.50565092
9MP0004742_abnormal_vestibular_system2.36173311
10MP0002638_abnormal_pupillary_reflex2.26454598
11MP0003646_muscle_fatigue2.19978340
12MP0003880_abnormal_central_pattern2.11710664
13MP0005423_abnormal_somatic_nervous2.11676786
14MP0004142_abnormal_muscle_tone2.08147844
15MP0006292_abnormal_olfactory_placode2.08069187
16MP0003123_paternal_imprinting2.01671370
17MP0008875_abnormal_xenobiotic_pharmacok1.97512762
18MP0001968_abnormal_touch/_nociception1.97471709
19MP0002102_abnormal_ear_morphology1.94456828
20MP0001984_abnormal_olfaction1.87087584
21MP0003195_calcinosis1.82812154
22MP0005377_hearing/vestibular/ear_phenot1.80916149
23MP0003878_abnormal_ear_physiology1.80916149
24MP0002938_white_spotting1.74970880
25MP0003183_abnormal_peptide_metabolism1.72757833
26MP0008872_abnormal_physiological_respon1.72549464
27MP0005551_abnormal_eye_electrophysiolog1.69952234
28MP0003136_yellow_coat_color1.69168759
29MP0003121_genomic_imprinting1.68483318
30MP0002272_abnormal_nervous_system1.66851459
31MP0001293_anophthalmia1.64581727
32MP0005394_taste/olfaction_phenotype1.58111917
33MP0005499_abnormal_olfactory_system1.58111917
34MP0003122_maternal_imprinting1.56205171
35MP0000372_irregular_coat_pigmentation1.54833184
36MP0002736_abnormal_nociception_after1.53890033
37MP0001485_abnormal_pinna_reflex1.51021065
38MP0002876_abnormal_thyroid_physiology1.47651317
39MP0005253_abnormal_eye_physiology1.43106177
40MP0002095_abnormal_skin_pigmentation1.42618430
41MP0005171_absent_coat_pigmentation1.41759384
42MP0003011_delayed_dark_adaptation1.38849728
43MP0009745_abnormal_behavioral_response1.38763472
44MP0005360_urolithiasis1.37825977
45MP0002139_abnormal_hepatobiliary_system1.34400471
46MP0005379_endocrine/exocrine_gland_phen1.32597494
47MP0000566_synostosis1.30954681
48MP0005085_abnormal_gallbladder_physiolo1.27929231
49MP0006072_abnormal_retinal_apoptosis1.25358232
50MP0000049_abnormal_middle_ear1.25148030
51MP0002735_abnormal_chemical_nociception1.23805636
52MP0005645_abnormal_hypothalamus_physiol1.23541960
53MP0001440_abnormal_grooming_behavior1.21386309
54MP0003959_abnormal_lean_body1.19827588
55MP0001529_abnormal_vocalization1.17489574
56MP0000778_abnormal_nervous_system1.15263962
57MP0001905_abnormal_dopamine_level1.12147600
58MP0002163_abnormal_gland_morphology1.10823957
59MP0001970_abnormal_pain_threshold1.09302860
60MP0003186_abnormal_redox_activity1.08531866
61MP0004043_abnormal_pH_regulation1.07838377
62MP0000631_abnormal_neuroendocrine_gland1.07156602
63MP0001501_abnormal_sleep_pattern1.07146266
64MP0002733_abnormal_thermal_nociception1.06176396
65MP0002067_abnormal_sensory_capabilities1.05486012
66MP0005671_abnormal_response_to1.05186679
67MP0002557_abnormal_social/conspecific_i1.05183235
68MP0004133_heterotaxia1.01564496
69MP0005503_abnormal_tendon_morphology1.01382886
70MP0002734_abnormal_mechanical_nocicepti0.99628798
71MP0006276_abnormal_autonomic_nervous0.95731187
72MP0002572_abnormal_emotion/affect_behav0.95281918
73MP0004145_abnormal_muscle_electrophysio0.89898421
74MP0003638_abnormal_response/metabolism_0.89134948
75MP0001986_abnormal_taste_sensitivity0.88470949
76MP0002233_abnormal_nose_morphology0.85835475
77MP0005187_abnormal_penis_morphology0.85667486
78MP0009780_abnormal_chondrocyte_physiolo0.84838616
79MP0002837_dystrophic_cardiac_calcinosis0.84701883
80MP0000015_abnormal_ear_pigmentation0.83602566
81MP0002063_abnormal_learning/memory/cond0.82079129
82MP0005075_abnormal_melanosome_morpholog0.80831435
83MP0005391_vision/eye_phenotype0.80545954
84MP0001486_abnormal_startle_reflex0.80034830
85MP0002064_seizures0.79961292
86MP0005195_abnormal_posterior_eye0.79003363
87MP0009053_abnormal_anal_canal0.77429108
88MP0002184_abnormal_innervation0.75826359
89MP0003119_abnormal_digestive_system0.75049777
90MP0000579_abnormal_nail_morphology0.74497377
91MP0002277_abnormal_respiratory_mucosa0.72462107
92MP0001764_abnormal_homeostasis0.71918251
93MP0002160_abnormal_reproductive_system0.71843173
94MP0002928_abnormal_bile_duct0.71591401
95MP0003635_abnormal_synaptic_transmissio0.71478495
96MP0000955_abnormal_spinal_cord0.69826125
97MP0001663_abnormal_digestive_system0.69491050
98MP0000026_abnormal_inner_ear0.68549730
99MP0003937_abnormal_limbs/digits/tail_de0.66129817
100MP0002752_abnormal_somatic_nervous0.65143792

Predicted human phenotypes

RankGene SetZ-score
1Septo-optic dysplasia (HP:0100842)4.30147970
2Degeneration of the lateral corticospinal tracts (HP:0002314)3.75079017
3Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.75079017
4Abnormal biliary tract physiology (HP:0012439)3.66779884
5Bile duct proliferation (HP:0001408)3.66779884
6Rib fusion (HP:0000902)3.39126140
7Reticulocytopenia (HP:0001896)3.35461671
8Abnormality of cells of the erythroid lineage (HP:0012130)3.35385257
9Growth hormone deficiency (HP:0000824)3.03053616
10Hyperglycinemia (HP:0002154)3.01329869
11Absent rod-and cone-mediated responses on ERG (HP:0007688)2.97223233
12Absent septum pellucidum (HP:0001331)2.93024974
13Congenital, generalized hypertrichosis (HP:0004540)2.92819416
14Acute necrotizing encephalopathy (HP:0006965)2.88709090
15Acute encephalopathy (HP:0006846)2.88337116
16Abnormality of the corticospinal tract (HP:0002492)2.87284975
17Supernumerary bones of the axial skeleton (HP:0009144)2.80699708
18Hypoplasia of the radius (HP:0002984)2.78344058
19Tented upper lip vermilion (HP:0010804)2.77179613
20Abnormal number of erythroid precursors (HP:0012131)2.76799407
21Molar tooth sign on MRI (HP:0002419)2.74694809
22Abnormality of midbrain morphology (HP:0002418)2.74694809
23Anophthalmia (HP:0000528)2.71660623
24Abnormality of alanine metabolism (HP:0010916)2.69276201
25Hyperalaninemia (HP:0003348)2.69276201
26Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.69276201
27Medial flaring of the eyebrow (HP:0010747)2.69174262
283-Methylglutaconic aciduria (HP:0003535)2.68636411
29Hypoplasia of the ulna (HP:0003022)2.68543143
30Abnormal mitochondria in muscle tissue (HP:0008316)2.64812395
31Abolished electroretinogram (ERG) (HP:0000550)2.64420390
32Forearm undergrowth (HP:0009821)2.63808791
33Abnormal rod and cone electroretinograms (HP:0008323)2.63487236
34Bilateral microphthalmos (HP:0007633)2.60766304
35Optic nerve hypoplasia (HP:0000609)2.60029210
36Type II lissencephaly (HP:0007260)2.59505691
37Abnormality of the septum pellucidum (HP:0007375)2.53057857
38Methylmalonic acidemia (HP:0002912)2.52565391
39Adrenal hypoplasia (HP:0000835)2.52116717
40Congenital stationary night blindness (HP:0007642)2.50927732
41Hemivertebrae (HP:0002937)2.50462134
42Chorioretinal atrophy (HP:0000533)2.47113536
43Pendular nystagmus (HP:0012043)2.44202540
44Aplasia/Hypoplasia of the ulna (HP:0006495)2.43371188
45Horseshoe kidney (HP:0000085)2.41034855
46Polyphagia (HP:0002591)2.37702856
47Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.32876460
48Gait imbalance (HP:0002141)2.32010853
49Mitochondrial inheritance (HP:0001427)2.25687685
50Symphalangism affecting the phalanges of the hand (HP:0009773)2.23956766
51Progressive macrocephaly (HP:0004481)2.19494565
52Down-sloping shoulders (HP:0200021)2.18931223
53Congenital primary aphakia (HP:0007707)2.17767075
54Pancreatic cysts (HP:0001737)2.15075985
55Macrocytic anemia (HP:0001972)2.10206253
56Anterior segment dysgenesis (HP:0007700)2.09675003
57Methylmalonic aciduria (HP:0012120)2.06372206
58Abnormality of the renal cortex (HP:0011035)2.01614932
59Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.01475154
60Short 4th metacarpal (HP:0010044)2.01475154
61Renal cortical cysts (HP:0000803)2.01349710
62Sclerocornea (HP:0000647)2.00395071
63Cleft eyelid (HP:0000625)2.00000475
64Asplenia (HP:0001746)1.98145138
65Aplasia/Hypoplasia of the uvula (HP:0010293)1.97650727
66Brittle hair (HP:0002299)1.97453673
67Agitation (HP:0000713)1.96719202
68Oligodactyly (hands) (HP:0001180)1.95092435
69Increased serum lactate (HP:0002151)1.94621410
70Pancreatic fibrosis (HP:0100732)1.94421101
71Aplasia/Hypoplasia of the spleen (HP:0010451)1.92898287
72Abnormality of the phalanges of the 5th finger (HP:0004213)1.92818929
73Increased CSF lactate (HP:0002490)1.91244579
74Short thumb (HP:0009778)1.91230162
75Abnormality of the labia minora (HP:0012880)1.90768882
76Hepatoblastoma (HP:0002884)1.89725643
77Status epilepticus (HP:0002133)1.88021475
78Abnormality of the diencephalon (HP:0010662)1.87622222
79Focal seizures (HP:0007359)1.87393074
80Cupped ear (HP:0000378)1.86382571
81Lethargy (HP:0001254)1.85819175
82Large for gestational age (HP:0001520)1.85729889
83Cerebral edema (HP:0002181)1.84833361
84Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.83953587
85Optic disc pallor (HP:0000543)1.82334396
86Pallor (HP:0000980)1.82244855
87Abnormal number of incisors (HP:0011064)1.81260059
88Cerebral hypomyelination (HP:0006808)1.80862003
89Abnormality of the 4th metacarpal (HP:0010012)1.79688213
90Absent thumb (HP:0009777)1.79476587
91Depressed nasal tip (HP:0000437)1.77746152
92Woolly hair (HP:0002224)1.77225835
93Ectopic kidney (HP:0000086)1.76316474
94Lactic acidosis (HP:0003128)1.76160458
95Trigonocephaly (HP:0000243)1.75760153
96Abnormality of the ileum (HP:0001549)1.75751984
97Nephronophthisis (HP:0000090)1.74663507
98Aplasia/Hypoplasia of the sternum (HP:0006714)1.74337229
99Nephrogenic diabetes insipidus (HP:0009806)1.73757542
100Mesomelia (HP:0003027)1.73346844

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MUSK4.21320192
2ADRBK24.19428185
3TXK3.66900513
4EPHA42.55431878
5EPHA32.54229732
6TAOK32.53100370
7BCKDK2.37637449
8GRK12.37489782
9MKNK22.07335494
10MAP3K42.06280878
11DYRK22.03012552
12WNK32.00448151
13WNK41.96192601
14BMPR1B1.94766960
15PINK11.94575134
16PBK1.80087320
17NTRK21.78329934
18PIK3CG1.73014235
19STK38L1.69719350
20CAMKK21.59095155
21INSRR1.55860803
22TYRO31.54400040
23MAP2K71.53105186
24LATS11.48560441
25MAP3K111.46660446
26CDC71.45459877
27EPHB21.44763784
28TNIK1.36272405
29MAP3K121.29649047
30GRK61.25325494
31TIE11.21588674
32PIK3CA1.19619926
33PDK21.18446447
34MAP4K11.16691480
35SRPK11.14898963
36PRKCG1.13106257
37SIK21.12594985
38NUAK11.11498645
39MAP4K21.05006784
40PLK41.03337220
41CDK191.03223951
42PAK31.02925460
43VRK21.02000976
44LRRK21.01520725
45ZAK1.00198951
46IKBKE0.97760595
47FRK0.90676894
48AKT30.89740304
49TSSK60.88742144
50TLK10.86589694
51MKNK10.84233648
52MAP2K40.82940789
53STK160.81000129
54CAMKK10.78584676
55ADRBK10.76073135
56TNK20.75412499
57TYK20.75268347
58RPS6KA50.72449836
59NEK10.71099162
60VRK10.68829550
61MAP2K20.67133266
62CDK30.63823760
63CSNK2A20.59414470
64KIT0.59292077
65FGR0.59037824
66CAMK10.58144843
67NME10.57699948
68PHKG10.56160978
69PHKG20.56160978
70BRSK20.55853470
71IKBKB0.55376161
72PIM20.54234709
73NTRK30.52814529
74JAK30.51000999
75RPS6KA10.48365024
76TGFBR10.47494851
77PNCK0.47438671
78MARK10.47094594
79PRKACA0.46662284
80STK390.44709508
81SGK4940.41051495
82SGK2230.41051495
83PLK20.40555074
84MATK0.40335084
85ABL20.39029968
86EIF2AK10.36395437
87OBSCN0.34658243
88WEE10.33842848
89PRKACB0.33480711
90CSNK2A10.33041284
91PRKACG0.31519410
92MAPK150.31475685
93JAK10.31146202
94SGK20.30583920
95LCK0.30223902
96CSNK1E0.28697971
97STK30.28502502
98PRKCH0.25212446
99OXSR10.24820130
100CAMK2A0.23882148

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.35683251
2Oxidative phosphorylation_Homo sapiens_hsa001903.06835058
3Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.53672761
4Parkinsons disease_Homo sapiens_hsa050122.46927228
5Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.43468480
6Cardiac muscle contraction_Homo sapiens_hsa042602.24715513
7Caffeine metabolism_Homo sapiens_hsa002322.19440018
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.16932447
9RNA polymerase_Homo sapiens_hsa030202.15151538
10One carbon pool by folate_Homo sapiens_hsa006702.13998137
11Linoleic acid metabolism_Homo sapiens_hsa005912.08568139
12Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.05309853
13Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.04056755
14Steroid hormone biosynthesis_Homo sapiens_hsa001401.81753831
15Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.81290161
16Peroxisome_Homo sapiens_hsa041461.78421729
17Steroid biosynthesis_Homo sapiens_hsa001001.77717956
18Nicotine addiction_Homo sapiens_hsa050331.70625214
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.61192463
20Huntingtons disease_Homo sapiens_hsa050161.55198748
21Nitrogen metabolism_Homo sapiens_hsa009101.50864630
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.47673168
23Retinol metabolism_Homo sapiens_hsa008301.47045766
24Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.46789648
25Chemical carcinogenesis_Homo sapiens_hsa052041.46619885
26Alzheimers disease_Homo sapiens_hsa050101.44330224
27Pyruvate metabolism_Homo sapiens_hsa006201.41387186
28Propanoate metabolism_Homo sapiens_hsa006401.40206516
29Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.39565969
30beta-Alanine metabolism_Homo sapiens_hsa004101.38982592
31Tryptophan metabolism_Homo sapiens_hsa003801.34282495
32Histidine metabolism_Homo sapiens_hsa003401.33318369
33Protein export_Homo sapiens_hsa030601.32388231
34Asthma_Homo sapiens_hsa053101.30409719
35Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.28311567
36Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.25404907
37Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.23607659
38Cyanoamino acid metabolism_Homo sapiens_hsa004601.17945313
39Intestinal immune network for IgA production_Homo sapiens_hsa046721.16522926
40Basal cell carcinoma_Homo sapiens_hsa052171.16310323
41alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.16195599
42Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.15555853
43Phototransduction_Homo sapiens_hsa047441.14460363
44Hedgehog signaling pathway_Homo sapiens_hsa043401.13495731
45Primary bile acid biosynthesis_Homo sapiens_hsa001201.08838726
46RNA degradation_Homo sapiens_hsa030181.04805648
47Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.02209511
48Ether lipid metabolism_Homo sapiens_hsa005651.01212951
49Fanconi anemia pathway_Homo sapiens_hsa034601.01128519
50Basal transcription factors_Homo sapiens_hsa030221.01120538
51Arginine and proline metabolism_Homo sapiens_hsa003300.96538821
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95481892
53Arachidonic acid metabolism_Homo sapiens_hsa005900.95126974
54Proteasome_Homo sapiens_hsa030500.94107801
55Homologous recombination_Homo sapiens_hsa034400.93502746
56Sulfur relay system_Homo sapiens_hsa041220.93451280
57Complement and coagulation cascades_Homo sapiens_hsa046100.92376824
58Cysteine and methionine metabolism_Homo sapiens_hsa002700.90214644
59Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.83715132
60Autoimmune thyroid disease_Homo sapiens_hsa053200.83321194
61Bile secretion_Homo sapiens_hsa049760.81574763
62Pyrimidine metabolism_Homo sapiens_hsa002400.81519334
63Butanoate metabolism_Homo sapiens_hsa006500.79990175
64Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.78289999
65Allograft rejection_Homo sapiens_hsa053300.77072502
66Metabolic pathways_Homo sapiens_hsa011000.73558161
67Glycerolipid metabolism_Homo sapiens_hsa005610.72953715
68Fatty acid degradation_Homo sapiens_hsa000710.72908014
69Fatty acid biosynthesis_Homo sapiens_hsa000610.72680386
70Taste transduction_Homo sapiens_hsa047420.71164755
71Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.70480823
72Nucleotide excision repair_Homo sapiens_hsa034200.68998140
73Maturity onset diabetes of the young_Homo sapiens_hsa049500.67370640
74Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.65421977
75Olfactory transduction_Homo sapiens_hsa047400.63678491
76Mismatch repair_Homo sapiens_hsa034300.59197640
77Ovarian steroidogenesis_Homo sapiens_hsa049130.55302732
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.51537674
79Starch and sucrose metabolism_Homo sapiens_hsa005000.50762522
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.48506230
81ABC transporters_Homo sapiens_hsa020100.48441469
82Pentose and glucuronate interconversions_Homo sapiens_hsa000400.47968088
83Insulin secretion_Homo sapiens_hsa049110.45529476
84Spliceosome_Homo sapiens_hsa030400.44805909
85Phenylalanine metabolism_Homo sapiens_hsa003600.44697721
86Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.44557964
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42971416
88Base excision repair_Homo sapiens_hsa034100.41628525
89Purine metabolism_Homo sapiens_hsa002300.40745521
90Drug metabolism - other enzymes_Homo sapiens_hsa009830.38797978
91Sulfur metabolism_Homo sapiens_hsa009200.38421104
92RNA transport_Homo sapiens_hsa030130.37396899
93Fat digestion and absorption_Homo sapiens_hsa049750.36816254
94Fatty acid metabolism_Homo sapiens_hsa012120.36803237
95Glutamatergic synapse_Homo sapiens_hsa047240.35631572
96DNA replication_Homo sapiens_hsa030300.33964765
97Primary immunodeficiency_Homo sapiens_hsa053400.33349658
98Lysine degradation_Homo sapiens_hsa003100.33164085
99Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.33097727
100Glycerophospholipid metabolism_Homo sapiens_hsa005640.32249669

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