RPL30P5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1water-soluble vitamin biosynthetic process (GO:0042364)6.95883779
2energy coupled proton transport, down electrochemical gradient (GO:0015985)5.43058334
3ATP synthesis coupled proton transport (GO:0015986)5.43058334
4behavioral response to nicotine (GO:0035095)5.00862146
5auditory receptor cell differentiation (GO:0042491)4.93909372
6viral transcription (GO:0019083)4.61479542
7response to pheromone (GO:0019236)4.57004965
8translational termination (GO:0006415)4.51579835
9ribosomal small subunit assembly (GO:0000028)4.10771365
10translational elongation (GO:0006414)4.06929705
11DNA deamination (GO:0045006)4.01903659
12ribosomal small subunit biogenesis (GO:0042274)3.97857317
13epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.93349408
14regulation of cilium movement (GO:0003352)3.90740748
15ribosomal large subunit biogenesis (GO:0042273)3.84638142
16fucose catabolic process (GO:0019317)3.74395068
17L-fucose metabolic process (GO:0042354)3.74395068
18L-fucose catabolic process (GO:0042355)3.74395068
19SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.71616895
20protein localization to Golgi apparatus (GO:0034067)3.67908451
21mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.65846987
22cellular ketone body metabolic process (GO:0046950)3.64639131
23cotranslational protein targeting to membrane (GO:0006613)3.62126234
24cellular response to interferon-beta (GO:0035458)3.60619048
25protein targeting to ER (GO:0045047)3.60526940
26protein localization to endoplasmic reticulum (GO:0070972)3.60198921
27ovulation cycle (GO:0042698)3.59067946
28regulation of microtubule-based movement (GO:0060632)3.56416679
29nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.56180797
30short-chain fatty acid metabolic process (GO:0046459)3.54450067
31tyrosine phosphorylation of STAT protein (GO:0007260)3.48724705
32nonmotile primary cilium assembly (GO:0035058)3.46218089
33oxidative demethylation (GO:0070989)3.44459216
34protein neddylation (GO:0045116)3.44166189
35positive regulation of cell fate commitment (GO:0010455)3.42124630
36establishment of protein localization to endoplasmic reticulum (GO:0072599)3.41459014
37neurofilament cytoskeleton organization (GO:0060052)3.40943409
38hormone catabolic process (GO:0042447)3.35123422
39nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.33453066
40cellular protein complex disassembly (GO:0043624)3.25321352
41vitamin biosynthetic process (GO:0009110)3.25224771
42ketone body metabolic process (GO:1902224)3.23384740
43tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.22834968
44RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.22834968
45rRNA catabolic process (GO:0016075)3.22384675
46viral life cycle (GO:0019058)3.22166043
47phenol-containing compound catabolic process (GO:0019336)3.16903947
48regulation of female gonad development (GO:2000194)3.15896487
49DNA damage response, detection of DNA damage (GO:0042769)3.13830589
50exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13692495
51opioid receptor signaling pathway (GO:0038003)3.12566401
52behavioral response to ethanol (GO:0048149)3.09547421
53positive regulation of defense response to virus by host (GO:0002230)3.09081764
54genetic imprinting (GO:0071514)3.08765594
55mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.08020168
56mitochondrial respiratory chain complex I assembly (GO:0032981)3.08020168
57NADH dehydrogenase complex assembly (GO:0010257)3.08020168
58histone H3-K36 demethylation (GO:0070544)3.07458005
59adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.04887916
60maturation of SSU-rRNA (GO:0030490)3.04158723
61negative regulation of protein tyrosine kinase activity (GO:0061099)3.03793311
62mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.01541295
63regulation of transmission of nerve impulse (GO:0051969)2.99333693
64regulation of protein glycosylation (GO:0060049)2.99178460
65detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.98587986
66protein complex biogenesis (GO:0070271)2.97262579
67thyroid hormone generation (GO:0006590)2.95888751
68kidney morphogenesis (GO:0060993)2.95664652
69retrograde transport, vesicle recycling within Golgi (GO:0000301)2.94950378
70myoblast migration (GO:0051451)2.94888005
71ether lipid metabolic process (GO:0046485)2.94707744
72protein polyglutamylation (GO:0018095)2.93209517
73negative regulation of cAMP-mediated signaling (GO:0043951)2.92604643
74protein targeting to Golgi (GO:0000042)2.92401219
75establishment of protein localization to Golgi (GO:0072600)2.91002239
76ncRNA catabolic process (GO:0034661)2.89173888
77lateral ventricle development (GO:0021670)2.88669651
78negative regulation of mast cell activation (GO:0033004)2.88037709
79artery smooth muscle contraction (GO:0014824)2.84825157
80ATP biosynthetic process (GO:0006754)2.84060770
81folic acid-containing compound biosynthetic process (GO:0009396)2.83546033
82translational initiation (GO:0006413)2.82984050
83electron transport chain (GO:0022900)2.73210163
84negative regulation of telomere maintenance (GO:0032205)2.72748058
85regulation of gene expression by genetic imprinting (GO:0006349)2.69777140
86translation (GO:0006412)2.67528494
87respiratory electron transport chain (GO:0022904)2.67131533
88respiratory chain complex IV assembly (GO:0008535)2.66846616
89protein complex disassembly (GO:0043241)2.65481177
90peptidyl-histidine modification (GO:0018202)2.64468011
91regulation of bile acid biosynthetic process (GO:0070857)2.63288168
92purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.61884512
93response to interferon-beta (GO:0035456)2.61723468
94sulfation (GO:0051923)2.60997687
95thyroid hormone metabolic process (GO:0042403)2.58034039
96signal peptide processing (GO:0006465)2.57525201
97pteridine-containing compound biosynthetic process (GO:0042559)2.56895580
98macromolecular complex disassembly (GO:0032984)2.56014409
99tetrahydrofolate metabolic process (GO:0046653)2.54936781
100mitochondrial respiratory chain complex assembly (GO:0033108)2.54014926

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.89444353
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.41805536
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.93737152
4HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.83859888
5VDR_22108803_ChIP-Seq_LS180_Human2.70212714
6FLI1_27457419_Chip-Seq_LIVER_Mouse2.61609837
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.51857804
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.47169399
9ZNF274_21170338_ChIP-Seq_K562_Hela2.32997391
10ETS1_20019798_ChIP-Seq_JURKAT_Human2.16630627
11PCGF2_27294783_Chip-Seq_NPCs_Mouse2.10455521
12GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.10195564
13ELF1_17652178_ChIP-ChIP_JURKAT_Human2.01986704
14VDR_23849224_ChIP-Seq_CD4+_Human1.99324043
15CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.89655871
16PCGF2_27294783_Chip-Seq_ESCs_Mouse1.80994812
17EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.76503433
18JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.71989264
19TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.66447292
20TP53_22573176_ChIP-Seq_HFKS_Human1.60076140
21EWS_26573619_Chip-Seq_HEK293_Human1.55538695
22CIITA_25753668_ChIP-Seq_RAJI_Human1.55387149
23IRF1_19129219_ChIP-ChIP_H3396_Human1.51921096
24NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.49820556
25REST_21632747_ChIP-Seq_MESCs_Mouse1.49256646
26IKZF1_21737484_ChIP-ChIP_HCT116_Human1.48887078
27KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.48528256
28ER_23166858_ChIP-Seq_MCF-7_Human1.45978079
29GATA3_21878914_ChIP-Seq_MCF-7_Human1.44732258
30EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.44416111
31CTBP2_25329375_ChIP-Seq_LNCAP_Human1.44223730
32NANOG_20526341_ChIP-Seq_ESCs_Human1.43659766
33RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42975958
34MYC_18940864_ChIP-ChIP_HL60_Human1.41437554
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.37666155
36NFE2_27457419_Chip-Seq_LIVER_Mouse1.36336589
37REST_18959480_ChIP-ChIP_MESCs_Mouse1.34700649
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.34427439
39TDRD3_21172665_ChIP-Seq_MCF-7_Human1.34188115
40SRF_21415370_ChIP-Seq_HL-1_Mouse1.31278435
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.30871046
42TTF2_22483619_ChIP-Seq_HELA_Human1.28820439
43CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.28561197
44ZFP57_27257070_Chip-Seq_ESCs_Mouse1.28257028
45CBP_20019798_ChIP-Seq_JUKART_Human1.27513503
46IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.27513503
47NANOG_19829295_ChIP-Seq_ESCs_Human1.25941847
48SOX2_19829295_ChIP-Seq_ESCs_Human1.25941847
49TAF2_19829295_ChIP-Seq_ESCs_Human1.24071041
50FUS_26573619_Chip-Seq_HEK293_Human1.23019782
51MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.21874920
52FOXA1_25329375_ChIP-Seq_VCAP_Human1.21615924
53FOXA1_27270436_Chip-Seq_PROSTATE_Human1.21615924
54LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.21260429
55CBX2_27304074_Chip-Seq_ESCs_Mouse1.21144695
56PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.20789949
57GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.19647087
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.18536491
59TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.18001811
60POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.18001811
61P300_19829295_ChIP-Seq_ESCs_Human1.17858374
62AUTS2_25519132_ChIP-Seq_293T-REX_Human1.16502047
63E2F1_20622854_ChIP-Seq_HELA_Human1.16281686
64MYC_19829295_ChIP-Seq_ESCs_Human1.15222137
65RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.13643283
66BCAT_22108803_ChIP-Seq_LS180_Human1.13103614
67SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12915560
68GBX2_23144817_ChIP-Seq_PC3_Human1.11227951
69P53_21459846_ChIP-Seq_SAOS-2_Human1.10872095
70FOXH1_21741376_ChIP-Seq_ESCs_Human1.09792945
71CEBPB_22108803_ChIP-Seq_LS180_Human1.09477462
72ELF1_20517297_ChIP-Seq_JURKAT_Human1.09191673
73POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.08913820
74GABP_19822575_ChIP-Seq_HepG2_Human1.08883903
75CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.07916977
76TAF15_26573619_Chip-Seq_HEK293_Human1.06579501
77ERA_21632823_ChIP-Seq_H3396_Human1.04902593
78FOXH1_21741376_ChIP-Seq_EPCs_Human1.03625975
79MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.01956991
80HOXB7_26014856_ChIP-Seq_BT474_Human1.01899301
81AR_20517297_ChIP-Seq_VCAP_Human1.00221919
82SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99195025
83KLF5_20875108_ChIP-Seq_MESCs_Mouse0.97196858
84EZH2_27294783_Chip-Seq_ESCs_Mouse0.96973019
85ETV2_25802403_ChIP-Seq_MESCs_Mouse0.96578807
86BCL6_27268052_Chip-Seq_Bcells_Human0.95690191
87TCF4_22108803_ChIP-Seq_LS180_Human0.95530400
88GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.95119380
89GATA6_21074721_ChIP-Seq_CACO-2_Human0.93229779
90GATA3_21867929_ChIP-Seq_TH1_Mouse0.93051016
91YY1_22570637_ChIP-Seq_MALME-3M_Human0.92764699
92EGR1_23403033_ChIP-Seq_LIVER_Mouse0.92652424
93PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.92117259
94NCOR_22424771_ChIP-Seq_293T_Human0.92037657
95RAC3_21632823_ChIP-Seq_H3396_Human0.92033595
96FOXP3_21729870_ChIP-Seq_TREG_Human0.91140346
97ELK1_19687146_ChIP-ChIP_HELA_Human0.90816233
98RNF2_27304074_Chip-Seq_NSC_Mouse0.90487274
99STAT1_20625510_ChIP-Seq_HELA_Human0.90214359
100P300_27268052_Chip-Seq_Bcells_Human0.89442176

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003122_maternal_imprinting3.85336345
2MP0009379_abnormal_foot_pigmentation3.61377669
3MP0003787_abnormal_imprinting3.20839343
4MP0003121_genomic_imprinting2.80218793
5MP0005646_abnormal_pituitary_gland2.71019051
6MP0000372_irregular_coat_pigmentation2.44810570
7MP0003646_muscle_fatigue2.43301790
8MP0008877_abnormal_DNA_methylation2.41869275
9MP0002163_abnormal_gland_morphology2.27831384
10MP0006292_abnormal_olfactory_placode2.27127849
11MP0001984_abnormal_olfaction2.25577300
12MP0001968_abnormal_touch/_nociception2.24701053
13MP0008789_abnormal_olfactory_epithelium2.15812037
14MP0008875_abnormal_xenobiotic_pharmacok2.07672815
15MP0003123_paternal_imprinting2.06010217
16MP0005187_abnormal_penis_morphology1.97200177
17MP0009780_abnormal_chondrocyte_physiolo1.96543099
18MP0002138_abnormal_hepatobiliary_system1.94913545
19MP0002876_abnormal_thyroid_physiology1.92319186
20MP0004742_abnormal_vestibular_system1.90215990
21MP0005394_taste/olfaction_phenotype1.85989924
22MP0005499_abnormal_olfactory_system1.85989924
23MP0005377_hearing/vestibular/ear_phenot1.83681890
24MP0003878_abnormal_ear_physiology1.83681890
25MP0006276_abnormal_autonomic_nervous1.82560766
26MP0002102_abnormal_ear_morphology1.80954295
27MP0005645_abnormal_hypothalamus_physiol1.78872338
28MP0002272_abnormal_nervous_system1.69296654
29MP0005423_abnormal_somatic_nervous1.66672511
30MP0003315_abnormal_perineum_morphology1.64278875
31MP0005084_abnormal_gallbladder_morpholo1.63123394
32MP0002938_white_spotting1.62433410
33MP0004133_heterotaxia1.60181090
34MP0005408_hypopigmentation1.58762905
35MP0002095_abnormal_skin_pigmentation1.51882362
36MP0003880_abnormal_central_pattern1.51067403
37MP0002736_abnormal_nociception_after1.49888413
38MP0005551_abnormal_eye_electrophysiolog1.46141600
39MP0004885_abnormal_endolymph1.44946300
40MP0000383_abnormal_hair_follicle1.43222453
41MP0001485_abnormal_pinna_reflex1.42962748
42MP0002928_abnormal_bile_duct1.42744444
43MP0008872_abnormal_physiological_respon1.37840096
44MP0004142_abnormal_muscle_tone1.36556650
45MP0001348_abnormal_lacrimal_gland1.29346982
46MP0005083_abnormal_biliary_tract1.28707770
47MP0009785_altered_susceptibility_to1.26682834
48MP0002557_abnormal_social/conspecific_i1.24580968
49MP0000427_abnormal_hair_cycle1.20597714
50MP0001970_abnormal_pain_threshold1.20247974
51MP0001835_abnormal_antigen_presentation1.17038445
52MP0005671_abnormal_response_to1.15980126
53MP0005379_endocrine/exocrine_gland_phen1.13709641
54MP0009764_decreased_sensitivity_to1.13519544
55MP0005174_abnormal_tail_pigmentation1.13170024
56MP0002733_abnormal_thermal_nociception1.12260446
57MP0003011_delayed_dark_adaptation1.10233426
58MP0001919_abnormal_reproductive_system1.08581834
59MP0009333_abnormal_splenocyte_physiolog1.06520902
60MP0006072_abnormal_retinal_apoptosis1.06208588
61MP0009046_muscle_twitch1.03485615
62MP0004147_increased_porphyrin_level1.02882620
63MP0002160_abnormal_reproductive_system1.01971964
64MP0001986_abnormal_taste_sensitivity1.01138225
65MP0004859_abnormal_synaptic_plasticity1.00936071
66MP0002837_dystrophic_cardiac_calcinosis1.00825955
67MP0001440_abnormal_grooming_behavior1.00596537
68MP0002653_abnormal_ependyma_morphology1.00255474
69MP0009745_abnormal_behavioral_response0.99879796
70MP0002572_abnormal_emotion/affect_behav0.91920132
71MP0001501_abnormal_sleep_pattern0.91791415
72MP0001529_abnormal_vocalization0.91781362
73MP0002063_abnormal_learning/memory/cond0.91636224
74MP0002184_abnormal_innervation0.91011242
75MP0003183_abnormal_peptide_metabolism0.90915674
76MP0008775_abnormal_heart_ventricle0.89208059
77MP0003786_premature_aging0.87678021
78MP0004782_abnormal_surfactant_physiolog0.87442809
79MP0000015_abnormal_ear_pigmentation0.86353294
80MP0003635_abnormal_synaptic_transmissio0.85961777
81MP0005387_immune_system_phenotype0.83696447
82MP0001790_abnormal_immune_system0.83696447
83MP0005389_reproductive_system_phenotype0.83446517
84MP0003879_abnormal_hair_cell0.83286461
85MP0000685_abnormal_immune_system0.82510904
86MP0000569_abnormal_digit_pigmentation0.80969281
87MP0001800_abnormal_humoral_immune0.80918014
88MP0000613_abnormal_salivary_gland0.80230331
89MP0010386_abnormal_urinary_bladder0.77306493
90MP0003938_abnormal_ear_development0.77301705
91MP0000049_abnormal_middle_ear0.76905506
92MP0001963_abnormal_hearing_physiology0.76100315
93MP0005075_abnormal_melanosome_morpholog0.74929826
94MP0001486_abnormal_startle_reflex0.73633329
95MP0003959_abnormal_lean_body0.71937982
96MP0002234_abnormal_pharynx_morphology0.71681816
97MP0002723_abnormal_immune_serum0.69961096
98MP0002067_abnormal_sensory_capabilities0.69108841
99MP0004145_abnormal_muscle_electrophysio0.67145772
100MP0001905_abnormal_dopamine_level0.66789525

Predicted human phenotypes

RankGene SetZ-score
1Type II lissencephaly (HP:0007260)4.72656080
2Increased hepatocellular lipid droplets (HP:0006565)4.18618216
3Methylmalonic acidemia (HP:0002912)4.05257629
4Lipid accumulation in hepatocytes (HP:0006561)4.02364012
5Abnormality of cells of the erythroid lineage (HP:0012130)3.89430490
6Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.83981397
73-Methylglutaconic aciduria (HP:0003535)3.69669503
8Abnormal number of erythroid precursors (HP:0012131)3.40425930
9Mitochondrial inheritance (HP:0001427)3.39723687
10Abnormality of the renal cortex (HP:0011035)3.30992322
11Renal Fanconi syndrome (HP:0001994)3.26841792
12Congenital, generalized hypertrichosis (HP:0004540)3.17814473
13Acute necrotizing encephalopathy (HP:0006965)3.17597744
14Aplasia/Hypoplasia of the spleen (HP:0010451)3.15042595
15Increased CSF lactate (HP:0002490)3.13709822
16Asplenia (HP:0001746)3.08025975
17Hyperglycinemia (HP:0002154)3.07436992
18Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.07358521
19Reticulocytopenia (HP:0001896)3.03718576
20Entropion (HP:0000621)3.03385955
21Retinal dysplasia (HP:0007973)3.00623887
22Molar tooth sign on MRI (HP:0002419)2.97280006
23Abnormality of midbrain morphology (HP:0002418)2.97280006
24Orchitis (HP:0100796)2.95550576
25Renal cortical cysts (HP:0000803)2.94458548
26Methylmalonic aciduria (HP:0012120)2.92237215
27Retrobulbar optic neuritis (HP:0100654)2.89547515
28Optic neuritis (HP:0100653)2.89547515
29Increased intramyocellular lipid droplets (HP:0012240)2.84468432
30Exertional dyspnea (HP:0002875)2.79789730
31Pancreatic cysts (HP:0001737)2.75462797
32Abnormal mitochondria in muscle tissue (HP:0008316)2.63270931
33Progressive macrocephaly (HP:0004481)2.63092591
34Tubulointerstitial fibrosis (HP:0005576)2.61709277
35Supernumerary spleens (HP:0009799)2.58013717
36Nephronophthisis (HP:0000090)2.51686165
37Pancreatic fibrosis (HP:0100732)2.48350179
38Submucous cleft hard palate (HP:0000176)2.46877662
39Increased muscle lipid content (HP:0009058)2.44327174
40Broad alveolar ridges (HP:0000187)2.43776846
41Pachygyria (HP:0001302)2.39841583
42Abnormality of the renal medulla (HP:0100957)2.39436868
43Calf muscle hypertrophy (HP:0008981)2.34969416
44Adrenal hypoplasia (HP:0000835)2.30928368
45Macrocytic anemia (HP:0001972)2.28620942
46Medial flaring of the eyebrow (HP:0010747)2.27413202
47Acute encephalopathy (HP:0006846)2.26896387
48Increased serum lactate (HP:0002151)2.25817043
49Abnormality of the vitamin B12 metabolism (HP:0004341)2.24778009
50Abnormality of renal resorption (HP:0011038)2.22335265
51Hepatocellular necrosis (HP:0001404)2.22294939
52Respiratory difficulties (HP:0002880)2.18404028
53Hepatic necrosis (HP:0002605)2.17749638
54Stenosis of the external auditory canal (HP:0000402)2.16895504
55Myositis (HP:0100614)2.16276806
56Congenital stationary night blindness (HP:0007642)2.15158706
57Abnormal drinking behavior (HP:0030082)2.15086292
58Polydipsia (HP:0001959)2.15086292
59Poikiloderma (HP:0001029)2.14141970
60Tubulointerstitial abnormality (HP:0001969)2.09866608
61Glycosuria (HP:0003076)2.07732364
62Abnormality of urine glucose concentration (HP:0011016)2.07732364
63Abnormality of vitamin B metabolism (HP:0004340)2.05818044
64Tubular atrophy (HP:0000092)2.03462665
65Muscle hypertrophy of the lower extremities (HP:0008968)2.03270758
66Chronic hepatic failure (HP:0100626)2.02077548
67Elevated erythrocyte sedimentation rate (HP:0003565)2.01411949
68Pallor (HP:0000980)2.00693170
69Keratoconjunctivitis (HP:0001096)1.97741013
70Congenital hepatic fibrosis (HP:0002612)1.96916074
71Ulnar deviation of the wrist (HP:0003049)1.96510131
72Lissencephaly (HP:0001339)1.96271584
73Anosmia (HP:0000458)1.95643315
74Abnormality of glycine metabolism (HP:0010895)1.94971130
75Abnormality of serine family amino acid metabolism (HP:0010894)1.94971130
76Attenuation of retinal blood vessels (HP:0007843)1.92301047
77Increased IgM level (HP:0003496)1.91397864
78Abnormality of alanine metabolism (HP:0010916)1.90119266
79Hyperalaninemia (HP:0003348)1.90119266
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.90119266
81Hyperphosphaturia (HP:0003109)1.89299617
82Pancytopenia (HP:0001876)1.89056801
83IgG deficiency (HP:0004315)1.88720981
84Generalized aminoaciduria (HP:0002909)1.86194705
85Portal hypertension (HP:0001409)1.84591568
86Abnormality of the aortic arch (HP:0012303)1.83291915
87Absent thumb (HP:0009777)1.82160075
88Chronic mucocutaneous candidiasis (HP:0002728)1.79960469
89Recurrent cutaneous fungal infections (HP:0011370)1.79960469
90Ketosis (HP:0001946)1.79272768
91Poor suck (HP:0002033)1.79240059
92Abnormality of the ileum (HP:0001549)1.78792090
93Optic nerve coloboma (HP:0000588)1.77927042
94Encephalitis (HP:0002383)1.77600662
95Abnormal pancreas size (HP:0012094)1.76114952
96Abnormality of macular pigmentation (HP:0008002)1.75919054
97Aplasia/Hypoplasia of the brainstem (HP:0007362)1.74228284
98Hypoplasia of the brainstem (HP:0002365)1.74228284
99Cerebral edema (HP:0002181)1.73415333
100Cerebellar dysplasia (HP:0007033)1.73414884

Predicted kinase interactions (KEA)

RankGene SetZ-score
1ADRBK24.40593739
2TXK4.37217902
3CDK193.72751790
4PASK3.63909722
5MAP4K13.05155875
6MAP2K63.03317140
7TSSK62.90630424
8NEK12.45961962
9TLK12.35624166
10TRIM282.21013244
11ZAK2.19200064
12PINK12.18396485
13GRK12.10562587
14BCKDK2.00758053
15NTRK21.99998098
16CAMKK11.98283453
17WNK41.86199804
18DYRK21.81211721
19EIF2AK11.79836935
20BMPR1B1.69280205
21STK161.56327579
22CAMKK21.55816943
23PTK61.52311977
24EPHB21.50355913
25NUAK11.42691004
26PRKCH1.42101949
27PRKCG1.39871260
28FGFR41.37182423
29RPS6KA51.24147279
30TIE11.20863281
31MINK11.15421619
32IKBKE1.12387495
33EIF2AK31.11831591
34PAK31.11606981
35FRK1.04653817
36ADRBK11.01949036
37IRAK10.97632178
38ITK0.95728119
39KIT0.94651336
40TEC0.92409663
41SGK2230.90160863
42SGK4940.90160863
43IKBKB0.88213987
44CDC70.84471529
45PRKCQ0.84219355
46PRKCE0.83915493
47TAF10.75799106
48CDK30.73273293
49SIK30.67462511
50ALK0.65918615
51BCR0.65704045
52SYK0.64234884
53SGK20.63473553
54CHUK0.62668690
55CAMK10.62491516
56MAP3K140.55999211
57VRK10.53613209
58CSNK1G20.53593164
59EPHA30.53226743
60EIF2AK20.53190300
61CSNK1E0.51487659
62TNIK0.50554793
63PRKCI0.49331109
64CSNK2A20.49035132
65AKT30.46494955
66PIK3CA0.46119963
67INSRR0.45918672
68RPS6KA60.45380743
69PRKCD0.45069080
70TGFBR10.44893923
71PIM20.44011842
72TGFBR20.43032288
73SIK20.41994623
74PRKCA0.41367460
75PLK20.39265205
76PRKACA0.39061443
77TYK20.38635333
78MAPK30.37128230
79NTRK30.36869318
80CAMK2A0.36318967
81OXSR10.36147586
82RPS6KA10.34321833
83PRKCB0.33496161
84STK40.33042763
85PRKCZ0.32563570
86OBSCN0.32441916
87NEK90.31313894
88LYN0.31033090
89ERN10.30818552
90SGK10.30471988
91CSNK1A10.30004265
92RPS6KC10.29702794
93RPS6KL10.29702794
94PRKACG0.29566940
95TAOK20.29537942
96CSNK2A10.28271072
97WNK30.28262301
98ATR0.28148251
99PRKG10.27902461
100SGK30.26638740

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.11663618
2One carbon pool by folate_Homo sapiens_hsa006703.51297716
3Oxidative phosphorylation_Homo sapiens_hsa001903.30170181
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.18899371
5Parkinsons disease_Homo sapiens_hsa050123.03629317
6Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.53141756
7Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.38087049
8Huntingtons disease_Homo sapiens_hsa050162.01661207
9Phototransduction_Homo sapiens_hsa047441.97697931
10Cardiac muscle contraction_Homo sapiens_hsa042601.94053002
11Butanoate metabolism_Homo sapiens_hsa006501.93181994
12Intestinal immune network for IgA production_Homo sapiens_hsa046721.92893936
13RNA degradation_Homo sapiens_hsa030181.92356513
14Proteasome_Homo sapiens_hsa030501.81920775
15Alzheimers disease_Homo sapiens_hsa050101.81233004
16Sulfur relay system_Homo sapiens_hsa041221.80275017
17Steroid biosynthesis_Homo sapiens_hsa001001.75164270
18Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.71353544
19Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.71236775
20RNA polymerase_Homo sapiens_hsa030201.67573025
21Linoleic acid metabolism_Homo sapiens_hsa005911.62684294
22Ether lipid metabolism_Homo sapiens_hsa005651.59629975
23Primary immunodeficiency_Homo sapiens_hsa053401.53629005
24Folate biosynthesis_Homo sapiens_hsa007901.53323070
25Type I diabetes mellitus_Homo sapiens_hsa049401.49604352
26alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.45398797
27Allograft rejection_Homo sapiens_hsa053301.44577816
28Caffeine metabolism_Homo sapiens_hsa002321.42708300
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.37031256
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.36799126
31Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.35250760
32Asthma_Homo sapiens_hsa053101.33928944
33Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.30250627
34Regulation of autophagy_Homo sapiens_hsa041401.30209370
35Steroid hormone biosynthesis_Homo sapiens_hsa001401.29247663
36Autoimmune thyroid disease_Homo sapiens_hsa053201.27676385
37Fatty acid biosynthesis_Homo sapiens_hsa000611.23935338
38Nicotine addiction_Homo sapiens_hsa050331.16837929
39Peroxisome_Homo sapiens_hsa041461.16177399
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.11258654
41Homologous recombination_Homo sapiens_hsa034401.09145577
42Protein export_Homo sapiens_hsa030601.07321203
43Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04375548
44Olfactory transduction_Homo sapiens_hsa047401.03561062
45Arachidonic acid metabolism_Homo sapiens_hsa005901.02880187
46Morphine addiction_Homo sapiens_hsa050321.01837454
47Pyrimidine metabolism_Homo sapiens_hsa002401.01404370
48Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.00914795
49Graft-versus-host disease_Homo sapiens_hsa053320.99109801
50Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.94514746
51Nitrogen metabolism_Homo sapiens_hsa009100.93553272
52Systemic lupus erythematosus_Homo sapiens_hsa053220.91592244
53Maturity onset diabetes of the young_Homo sapiens_hsa049500.85218572
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.85176660
55Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.84561041
56Propanoate metabolism_Homo sapiens_hsa006400.83580826
57Chemical carcinogenesis_Homo sapiens_hsa052040.82698814
58Basal transcription factors_Homo sapiens_hsa030220.80418359
59Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.75539593
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.75409148
61Tryptophan metabolism_Homo sapiens_hsa003800.74361601
62Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73452394
63GABAergic synapse_Homo sapiens_hsa047270.67193410
64Fat digestion and absorption_Homo sapiens_hsa049750.66985718
65Taste transduction_Homo sapiens_hsa047420.66348253
66Metabolic pathways_Homo sapiens_hsa011000.65028383
67Retinol metabolism_Homo sapiens_hsa008300.62510993
68RNA transport_Homo sapiens_hsa030130.62063221
69Purine metabolism_Homo sapiens_hsa002300.60738345
70Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.59013538
71Glycerolipid metabolism_Homo sapiens_hsa005610.56420587
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.54627536
73Antigen processing and presentation_Homo sapiens_hsa046120.53929086
74Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.51238279
75Ovarian steroidogenesis_Homo sapiens_hsa049130.50398797
76Hematopoietic cell lineage_Homo sapiens_hsa046400.50103410
77Insulin secretion_Homo sapiens_hsa049110.47468771
78NF-kappa B signaling pathway_Homo sapiens_hsa040640.45864016
79Fanconi anemia pathway_Homo sapiens_hsa034600.44896272
80Fatty acid metabolism_Homo sapiens_hsa012120.42199184
81Serotonergic synapse_Homo sapiens_hsa047260.39008119
82Mineral absorption_Homo sapiens_hsa049780.36642456
83Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.34962890
84Spliceosome_Homo sapiens_hsa030400.34626098
85Starch and sucrose metabolism_Homo sapiens_hsa005000.34000099
86Rheumatoid arthritis_Homo sapiens_hsa053230.31578827
87Alcoholism_Homo sapiens_hsa050340.30765338
88Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.30352626
89Fatty acid degradation_Homo sapiens_hsa000710.27792443
90Pentose and glucuronate interconversions_Homo sapiens_hsa000400.26591950
91Pyruvate metabolism_Homo sapiens_hsa006200.25370982
92Calcium signaling pathway_Homo sapiens_hsa040200.23834555
93Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.22413359
94mRNA surveillance pathway_Homo sapiens_hsa030150.20797765
95Cyanoamino acid metabolism_Homo sapiens_hsa004600.20742029
96Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.20044673
97beta-Alanine metabolism_Homo sapiens_hsa004100.18712419
98Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.18700702
99Cysteine and methionine metabolism_Homo sapiens_hsa002700.18191554
100Synaptic vesicle cycle_Homo sapiens_hsa047210.17390684

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