

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | water-soluble vitamin biosynthetic process (GO:0042364) | 6.95883779 |
| 2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.43058334 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 5.43058334 |
| 4 | behavioral response to nicotine (GO:0035095) | 5.00862146 |
| 5 | auditory receptor cell differentiation (GO:0042491) | 4.93909372 |
| 6 | viral transcription (GO:0019083) | 4.61479542 |
| 7 | response to pheromone (GO:0019236) | 4.57004965 |
| 8 | translational termination (GO:0006415) | 4.51579835 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.10771365 |
| 10 | translational elongation (GO:0006414) | 4.06929705 |
| 11 | DNA deamination (GO:0045006) | 4.01903659 |
| 12 | ribosomal small subunit biogenesis (GO:0042274) | 3.97857317 |
| 13 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.93349408 |
| 14 | regulation of cilium movement (GO:0003352) | 3.90740748 |
| 15 | ribosomal large subunit biogenesis (GO:0042273) | 3.84638142 |
| 16 | fucose catabolic process (GO:0019317) | 3.74395068 |
| 17 | L-fucose metabolic process (GO:0042354) | 3.74395068 |
| 18 | L-fucose catabolic process (GO:0042355) | 3.74395068 |
| 19 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.71616895 |
| 20 | protein localization to Golgi apparatus (GO:0034067) | 3.67908451 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.65846987 |
| 22 | cellular ketone body metabolic process (GO:0046950) | 3.64639131 |
| 23 | cotranslational protein targeting to membrane (GO:0006613) | 3.62126234 |
| 24 | cellular response to interferon-beta (GO:0035458) | 3.60619048 |
| 25 | protein targeting to ER (GO:0045047) | 3.60526940 |
| 26 | protein localization to endoplasmic reticulum (GO:0070972) | 3.60198921 |
| 27 | ovulation cycle (GO:0042698) | 3.59067946 |
| 28 | regulation of microtubule-based movement (GO:0060632) | 3.56416679 |
| 29 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.56180797 |
| 30 | short-chain fatty acid metabolic process (GO:0046459) | 3.54450067 |
| 31 | tyrosine phosphorylation of STAT protein (GO:0007260) | 3.48724705 |
| 32 | nonmotile primary cilium assembly (GO:0035058) | 3.46218089 |
| 33 | oxidative demethylation (GO:0070989) | 3.44459216 |
| 34 | protein neddylation (GO:0045116) | 3.44166189 |
| 35 | positive regulation of cell fate commitment (GO:0010455) | 3.42124630 |
| 36 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.41459014 |
| 37 | neurofilament cytoskeleton organization (GO:0060052) | 3.40943409 |
| 38 | hormone catabolic process (GO:0042447) | 3.35123422 |
| 39 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.33453066 |
| 40 | cellular protein complex disassembly (GO:0043624) | 3.25321352 |
| 41 | vitamin biosynthetic process (GO:0009110) | 3.25224771 |
| 42 | ketone body metabolic process (GO:1902224) | 3.23384740 |
| 43 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.22834968 |
| 44 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.22834968 |
| 45 | rRNA catabolic process (GO:0016075) | 3.22384675 |
| 46 | viral life cycle (GO:0019058) | 3.22166043 |
| 47 | phenol-containing compound catabolic process (GO:0019336) | 3.16903947 |
| 48 | regulation of female gonad development (GO:2000194) | 3.15896487 |
| 49 | DNA damage response, detection of DNA damage (GO:0042769) | 3.13830589 |
| 50 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.13692495 |
| 51 | opioid receptor signaling pathway (GO:0038003) | 3.12566401 |
| 52 | behavioral response to ethanol (GO:0048149) | 3.09547421 |
| 53 | positive regulation of defense response to virus by host (GO:0002230) | 3.09081764 |
| 54 | genetic imprinting (GO:0071514) | 3.08765594 |
| 55 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.08020168 |
| 56 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.08020168 |
| 57 | NADH dehydrogenase complex assembly (GO:0010257) | 3.08020168 |
| 58 | histone H3-K36 demethylation (GO:0070544) | 3.07458005 |
| 59 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 3.04887916 |
| 60 | maturation of SSU-rRNA (GO:0030490) | 3.04158723 |
| 61 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 3.03793311 |
| 62 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.01541295 |
| 63 | regulation of transmission of nerve impulse (GO:0051969) | 2.99333693 |
| 64 | regulation of protein glycosylation (GO:0060049) | 2.99178460 |
| 65 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.98587986 |
| 66 | protein complex biogenesis (GO:0070271) | 2.97262579 |
| 67 | thyroid hormone generation (GO:0006590) | 2.95888751 |
| 68 | kidney morphogenesis (GO:0060993) | 2.95664652 |
| 69 | retrograde transport, vesicle recycling within Golgi (GO:0000301) | 2.94950378 |
| 70 | myoblast migration (GO:0051451) | 2.94888005 |
| 71 | ether lipid metabolic process (GO:0046485) | 2.94707744 |
| 72 | protein polyglutamylation (GO:0018095) | 2.93209517 |
| 73 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.92604643 |
| 74 | protein targeting to Golgi (GO:0000042) | 2.92401219 |
| 75 | establishment of protein localization to Golgi (GO:0072600) | 2.91002239 |
| 76 | ncRNA catabolic process (GO:0034661) | 2.89173888 |
| 77 | lateral ventricle development (GO:0021670) | 2.88669651 |
| 78 | negative regulation of mast cell activation (GO:0033004) | 2.88037709 |
| 79 | artery smooth muscle contraction (GO:0014824) | 2.84825157 |
| 80 | ATP biosynthetic process (GO:0006754) | 2.84060770 |
| 81 | folic acid-containing compound biosynthetic process (GO:0009396) | 2.83546033 |
| 82 | translational initiation (GO:0006413) | 2.82984050 |
| 83 | electron transport chain (GO:0022900) | 2.73210163 |
| 84 | negative regulation of telomere maintenance (GO:0032205) | 2.72748058 |
| 85 | regulation of gene expression by genetic imprinting (GO:0006349) | 2.69777140 |
| 86 | translation (GO:0006412) | 2.67528494 |
| 87 | respiratory electron transport chain (GO:0022904) | 2.67131533 |
| 88 | respiratory chain complex IV assembly (GO:0008535) | 2.66846616 |
| 89 | protein complex disassembly (GO:0043241) | 2.65481177 |
| 90 | peptidyl-histidine modification (GO:0018202) | 2.64468011 |
| 91 | regulation of bile acid biosynthetic process (GO:0070857) | 2.63288168 |
| 92 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.61884512 |
| 93 | response to interferon-beta (GO:0035456) | 2.61723468 |
| 94 | sulfation (GO:0051923) | 2.60997687 |
| 95 | thyroid hormone metabolic process (GO:0042403) | 2.58034039 |
| 96 | signal peptide processing (GO:0006465) | 2.57525201 |
| 97 | pteridine-containing compound biosynthetic process (GO:0042559) | 2.56895580 |
| 98 | macromolecular complex disassembly (GO:0032984) | 2.56014409 |
| 99 | tetrahydrofolate metabolic process (GO:0046653) | 2.54936781 |
| 100 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.54014926 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.89444353 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.41805536 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.93737152 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.83859888 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.70212714 |
| 6 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.61609837 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.51857804 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.47169399 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.32997391 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.16630627 |
| 11 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.10455521 |
| 12 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.10195564 |
| 13 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.01986704 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.99324043 |
| 15 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.89655871 |
| 16 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.80994812 |
| 17 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.76503433 |
| 18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.71989264 |
| 19 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66447292 |
| 20 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.60076140 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.55538695 |
| 22 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.55387149 |
| 23 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.51921096 |
| 24 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.49820556 |
| 25 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.49256646 |
| 26 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.48887078 |
| 27 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.48528256 |
| 28 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.45978079 |
| 29 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.44732258 |
| 30 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.44416111 |
| 31 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.44223730 |
| 32 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.43659766 |
| 33 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.42975958 |
| 34 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.41437554 |
| 35 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.37666155 |
| 36 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36336589 |
| 37 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.34700649 |
| 38 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.34427439 |
| 39 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.34188115 |
| 40 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.31278435 |
| 41 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.30871046 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.28820439 |
| 43 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.28561197 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.28257028 |
| 45 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.27513503 |
| 46 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.27513503 |
| 47 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.25941847 |
| 48 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.25941847 |
| 49 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.24071041 |
| 50 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23019782 |
| 51 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.21874920 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.21615924 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.21615924 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21260429 |
| 55 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.21144695 |
| 56 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.20789949 |
| 57 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.19647087 |
| 58 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.18536491 |
| 59 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18001811 |
| 60 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.18001811 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.17858374 |
| 62 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.16502047 |
| 63 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.16281686 |
| 64 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.15222137 |
| 65 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.13643283 |
| 66 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.13103614 |
| 67 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.12915560 |
| 68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.11227951 |
| 69 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.10872095 |
| 70 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.09792945 |
| 71 | CEBPB_22108803_ChIP-Seq_LS180_Human | 1.09477462 |
| 72 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.09191673 |
| 73 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08913820 |
| 74 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.08883903 |
| 75 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07916977 |
| 76 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.06579501 |
| 77 | ERA_21632823_ChIP-Seq_H3396_Human | 1.04902593 |
| 78 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.03625975 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.01956991 |
| 80 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.01899301 |
| 81 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00221919 |
| 82 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.99195025 |
| 83 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97196858 |
| 84 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.96973019 |
| 85 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.96578807 |
| 86 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95690191 |
| 87 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.95530400 |
| 88 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.95119380 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.93229779 |
| 90 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.93051016 |
| 91 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.92764699 |
| 92 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92652424 |
| 93 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.92117259 |
| 94 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92037657 |
| 95 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92033595 |
| 96 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.91140346 |
| 97 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.90816233 |
| 98 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.90487274 |
| 99 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.90214359 |
| 100 | P300_27268052_Chip-Seq_Bcells_Human | 0.89442176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003122_maternal_imprinting | 3.85336345 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.61377669 |
| 3 | MP0003787_abnormal_imprinting | 3.20839343 |
| 4 | MP0003121_genomic_imprinting | 2.80218793 |
| 5 | MP0005646_abnormal_pituitary_gland | 2.71019051 |
| 6 | MP0000372_irregular_coat_pigmentation | 2.44810570 |
| 7 | MP0003646_muscle_fatigue | 2.43301790 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.41869275 |
| 9 | MP0002163_abnormal_gland_morphology | 2.27831384 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.27127849 |
| 11 | MP0001984_abnormal_olfaction | 2.25577300 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.24701053 |
| 13 | MP0008789_abnormal_olfactory_epithelium | 2.15812037 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 2.07672815 |
| 15 | MP0003123_paternal_imprinting | 2.06010217 |
| 16 | MP0005187_abnormal_penis_morphology | 1.97200177 |
| 17 | MP0009780_abnormal_chondrocyte_physiolo | 1.96543099 |
| 18 | MP0002138_abnormal_hepatobiliary_system | 1.94913545 |
| 19 | MP0002876_abnormal_thyroid_physiology | 1.92319186 |
| 20 | MP0004742_abnormal_vestibular_system | 1.90215990 |
| 21 | MP0005394_taste/olfaction_phenotype | 1.85989924 |
| 22 | MP0005499_abnormal_olfactory_system | 1.85989924 |
| 23 | MP0005377_hearing/vestibular/ear_phenot | 1.83681890 |
| 24 | MP0003878_abnormal_ear_physiology | 1.83681890 |
| 25 | MP0006276_abnormal_autonomic_nervous | 1.82560766 |
| 26 | MP0002102_abnormal_ear_morphology | 1.80954295 |
| 27 | MP0005645_abnormal_hypothalamus_physiol | 1.78872338 |
| 28 | MP0002272_abnormal_nervous_system | 1.69296654 |
| 29 | MP0005423_abnormal_somatic_nervous | 1.66672511 |
| 30 | MP0003315_abnormal_perineum_morphology | 1.64278875 |
| 31 | MP0005084_abnormal_gallbladder_morpholo | 1.63123394 |
| 32 | MP0002938_white_spotting | 1.62433410 |
| 33 | MP0004133_heterotaxia | 1.60181090 |
| 34 | MP0005408_hypopigmentation | 1.58762905 |
| 35 | MP0002095_abnormal_skin_pigmentation | 1.51882362 |
| 36 | MP0003880_abnormal_central_pattern | 1.51067403 |
| 37 | MP0002736_abnormal_nociception_after | 1.49888413 |
| 38 | MP0005551_abnormal_eye_electrophysiolog | 1.46141600 |
| 39 | MP0004885_abnormal_endolymph | 1.44946300 |
| 40 | MP0000383_abnormal_hair_follicle | 1.43222453 |
| 41 | MP0001485_abnormal_pinna_reflex | 1.42962748 |
| 42 | MP0002928_abnormal_bile_duct | 1.42744444 |
| 43 | MP0008872_abnormal_physiological_respon | 1.37840096 |
| 44 | MP0004142_abnormal_muscle_tone | 1.36556650 |
| 45 | MP0001348_abnormal_lacrimal_gland | 1.29346982 |
| 46 | MP0005083_abnormal_biliary_tract | 1.28707770 |
| 47 | MP0009785_altered_susceptibility_to | 1.26682834 |
| 48 | MP0002557_abnormal_social/conspecific_i | 1.24580968 |
| 49 | MP0000427_abnormal_hair_cycle | 1.20597714 |
| 50 | MP0001970_abnormal_pain_threshold | 1.20247974 |
| 51 | MP0001835_abnormal_antigen_presentation | 1.17038445 |
| 52 | MP0005671_abnormal_response_to | 1.15980126 |
| 53 | MP0005379_endocrine/exocrine_gland_phen | 1.13709641 |
| 54 | MP0009764_decreased_sensitivity_to | 1.13519544 |
| 55 | MP0005174_abnormal_tail_pigmentation | 1.13170024 |
| 56 | MP0002733_abnormal_thermal_nociception | 1.12260446 |
| 57 | MP0003011_delayed_dark_adaptation | 1.10233426 |
| 58 | MP0001919_abnormal_reproductive_system | 1.08581834 |
| 59 | MP0009333_abnormal_splenocyte_physiolog | 1.06520902 |
| 60 | MP0006072_abnormal_retinal_apoptosis | 1.06208588 |
| 61 | MP0009046_muscle_twitch | 1.03485615 |
| 62 | MP0004147_increased_porphyrin_level | 1.02882620 |
| 63 | MP0002160_abnormal_reproductive_system | 1.01971964 |
| 64 | MP0001986_abnormal_taste_sensitivity | 1.01138225 |
| 65 | MP0004859_abnormal_synaptic_plasticity | 1.00936071 |
| 66 | MP0002837_dystrophic_cardiac_calcinosis | 1.00825955 |
| 67 | MP0001440_abnormal_grooming_behavior | 1.00596537 |
| 68 | MP0002653_abnormal_ependyma_morphology | 1.00255474 |
| 69 | MP0009745_abnormal_behavioral_response | 0.99879796 |
| 70 | MP0002572_abnormal_emotion/affect_behav | 0.91920132 |
| 71 | MP0001501_abnormal_sleep_pattern | 0.91791415 |
| 72 | MP0001529_abnormal_vocalization | 0.91781362 |
| 73 | MP0002063_abnormal_learning/memory/cond | 0.91636224 |
| 74 | MP0002184_abnormal_innervation | 0.91011242 |
| 75 | MP0003183_abnormal_peptide_metabolism | 0.90915674 |
| 76 | MP0008775_abnormal_heart_ventricle | 0.89208059 |
| 77 | MP0003786_premature_aging | 0.87678021 |
| 78 | MP0004782_abnormal_surfactant_physiolog | 0.87442809 |
| 79 | MP0000015_abnormal_ear_pigmentation | 0.86353294 |
| 80 | MP0003635_abnormal_synaptic_transmissio | 0.85961777 |
| 81 | MP0005387_immune_system_phenotype | 0.83696447 |
| 82 | MP0001790_abnormal_immune_system | 0.83696447 |
| 83 | MP0005389_reproductive_system_phenotype | 0.83446517 |
| 84 | MP0003879_abnormal_hair_cell | 0.83286461 |
| 85 | MP0000685_abnormal_immune_system | 0.82510904 |
| 86 | MP0000569_abnormal_digit_pigmentation | 0.80969281 |
| 87 | MP0001800_abnormal_humoral_immune | 0.80918014 |
| 88 | MP0000613_abnormal_salivary_gland | 0.80230331 |
| 89 | MP0010386_abnormal_urinary_bladder | 0.77306493 |
| 90 | MP0003938_abnormal_ear_development | 0.77301705 |
| 91 | MP0000049_abnormal_middle_ear | 0.76905506 |
| 92 | MP0001963_abnormal_hearing_physiology | 0.76100315 |
| 93 | MP0005075_abnormal_melanosome_morpholog | 0.74929826 |
| 94 | MP0001486_abnormal_startle_reflex | 0.73633329 |
| 95 | MP0003959_abnormal_lean_body | 0.71937982 |
| 96 | MP0002234_abnormal_pharynx_morphology | 0.71681816 |
| 97 | MP0002723_abnormal_immune_serum | 0.69961096 |
| 98 | MP0002067_abnormal_sensory_capabilities | 0.69108841 |
| 99 | MP0004145_abnormal_muscle_electrophysio | 0.67145772 |
| 100 | MP0001905_abnormal_dopamine_level | 0.66789525 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Type II lissencephaly (HP:0007260) | 4.72656080 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 4.18618216 |
| 3 | Methylmalonic acidemia (HP:0002912) | 4.05257629 |
| 4 | Lipid accumulation in hepatocytes (HP:0006561) | 4.02364012 |
| 5 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.89430490 |
| 6 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.83981397 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.69669503 |
| 8 | Abnormal number of erythroid precursors (HP:0012131) | 3.40425930 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.39723687 |
| 10 | Abnormality of the renal cortex (HP:0011035) | 3.30992322 |
| 11 | Renal Fanconi syndrome (HP:0001994) | 3.26841792 |
| 12 | Congenital, generalized hypertrichosis (HP:0004540) | 3.17814473 |
| 13 | Acute necrotizing encephalopathy (HP:0006965) | 3.17597744 |
| 14 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.15042595 |
| 15 | Increased CSF lactate (HP:0002490) | 3.13709822 |
| 16 | Asplenia (HP:0001746) | 3.08025975 |
| 17 | Hyperglycinemia (HP:0002154) | 3.07436992 |
| 18 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.07358521 |
| 19 | Reticulocytopenia (HP:0001896) | 3.03718576 |
| 20 | Entropion (HP:0000621) | 3.03385955 |
| 21 | Retinal dysplasia (HP:0007973) | 3.00623887 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 2.97280006 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.97280006 |
| 24 | Orchitis (HP:0100796) | 2.95550576 |
| 25 | Renal cortical cysts (HP:0000803) | 2.94458548 |
| 26 | Methylmalonic aciduria (HP:0012120) | 2.92237215 |
| 27 | Retrobulbar optic neuritis (HP:0100654) | 2.89547515 |
| 28 | Optic neuritis (HP:0100653) | 2.89547515 |
| 29 | Increased intramyocellular lipid droplets (HP:0012240) | 2.84468432 |
| 30 | Exertional dyspnea (HP:0002875) | 2.79789730 |
| 31 | Pancreatic cysts (HP:0001737) | 2.75462797 |
| 32 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.63270931 |
| 33 | Progressive macrocephaly (HP:0004481) | 2.63092591 |
| 34 | Tubulointerstitial fibrosis (HP:0005576) | 2.61709277 |
| 35 | Supernumerary spleens (HP:0009799) | 2.58013717 |
| 36 | Nephronophthisis (HP:0000090) | 2.51686165 |
| 37 | Pancreatic fibrosis (HP:0100732) | 2.48350179 |
| 38 | Submucous cleft hard palate (HP:0000176) | 2.46877662 |
| 39 | Increased muscle lipid content (HP:0009058) | 2.44327174 |
| 40 | Broad alveolar ridges (HP:0000187) | 2.43776846 |
| 41 | Pachygyria (HP:0001302) | 2.39841583 |
| 42 | Abnormality of the renal medulla (HP:0100957) | 2.39436868 |
| 43 | Calf muscle hypertrophy (HP:0008981) | 2.34969416 |
| 44 | Adrenal hypoplasia (HP:0000835) | 2.30928368 |
| 45 | Macrocytic anemia (HP:0001972) | 2.28620942 |
| 46 | Medial flaring of the eyebrow (HP:0010747) | 2.27413202 |
| 47 | Acute encephalopathy (HP:0006846) | 2.26896387 |
| 48 | Increased serum lactate (HP:0002151) | 2.25817043 |
| 49 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.24778009 |
| 50 | Abnormality of renal resorption (HP:0011038) | 2.22335265 |
| 51 | Hepatocellular necrosis (HP:0001404) | 2.22294939 |
| 52 | Respiratory difficulties (HP:0002880) | 2.18404028 |
| 53 | Hepatic necrosis (HP:0002605) | 2.17749638 |
| 54 | Stenosis of the external auditory canal (HP:0000402) | 2.16895504 |
| 55 | Myositis (HP:0100614) | 2.16276806 |
| 56 | Congenital stationary night blindness (HP:0007642) | 2.15158706 |
| 57 | Abnormal drinking behavior (HP:0030082) | 2.15086292 |
| 58 | Polydipsia (HP:0001959) | 2.15086292 |
| 59 | Poikiloderma (HP:0001029) | 2.14141970 |
| 60 | Tubulointerstitial abnormality (HP:0001969) | 2.09866608 |
| 61 | Glycosuria (HP:0003076) | 2.07732364 |
| 62 | Abnormality of urine glucose concentration (HP:0011016) | 2.07732364 |
| 63 | Abnormality of vitamin B metabolism (HP:0004340) | 2.05818044 |
| 64 | Tubular atrophy (HP:0000092) | 2.03462665 |
| 65 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.03270758 |
| 66 | Chronic hepatic failure (HP:0100626) | 2.02077548 |
| 67 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.01411949 |
| 68 | Pallor (HP:0000980) | 2.00693170 |
| 69 | Keratoconjunctivitis (HP:0001096) | 1.97741013 |
| 70 | Congenital hepatic fibrosis (HP:0002612) | 1.96916074 |
| 71 | Ulnar deviation of the wrist (HP:0003049) | 1.96510131 |
| 72 | Lissencephaly (HP:0001339) | 1.96271584 |
| 73 | Anosmia (HP:0000458) | 1.95643315 |
| 74 | Abnormality of glycine metabolism (HP:0010895) | 1.94971130 |
| 75 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.94971130 |
| 76 | Attenuation of retinal blood vessels (HP:0007843) | 1.92301047 |
| 77 | Increased IgM level (HP:0003496) | 1.91397864 |
| 78 | Abnormality of alanine metabolism (HP:0010916) | 1.90119266 |
| 79 | Hyperalaninemia (HP:0003348) | 1.90119266 |
| 80 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.90119266 |
| 81 | Hyperphosphaturia (HP:0003109) | 1.89299617 |
| 82 | Pancytopenia (HP:0001876) | 1.89056801 |
| 83 | IgG deficiency (HP:0004315) | 1.88720981 |
| 84 | Generalized aminoaciduria (HP:0002909) | 1.86194705 |
| 85 | Portal hypertension (HP:0001409) | 1.84591568 |
| 86 | Abnormality of the aortic arch (HP:0012303) | 1.83291915 |
| 87 | Absent thumb (HP:0009777) | 1.82160075 |
| 88 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.79960469 |
| 89 | Recurrent cutaneous fungal infections (HP:0011370) | 1.79960469 |
| 90 | Ketosis (HP:0001946) | 1.79272768 |
| 91 | Poor suck (HP:0002033) | 1.79240059 |
| 92 | Abnormality of the ileum (HP:0001549) | 1.78792090 |
| 93 | Optic nerve coloboma (HP:0000588) | 1.77927042 |
| 94 | Encephalitis (HP:0002383) | 1.77600662 |
| 95 | Abnormal pancreas size (HP:0012094) | 1.76114952 |
| 96 | Abnormality of macular pigmentation (HP:0008002) | 1.75919054 |
| 97 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.74228284 |
| 98 | Hypoplasia of the brainstem (HP:0002365) | 1.74228284 |
| 99 | Cerebral edema (HP:0002181) | 1.73415333 |
| 100 | Cerebellar dysplasia (HP:0007033) | 1.73414884 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 4.40593739 |
| 2 | TXK | 4.37217902 |
| 3 | CDK19 | 3.72751790 |
| 4 | PASK | 3.63909722 |
| 5 | MAP4K1 | 3.05155875 |
| 6 | MAP2K6 | 3.03317140 |
| 7 | TSSK6 | 2.90630424 |
| 8 | NEK1 | 2.45961962 |
| 9 | TLK1 | 2.35624166 |
| 10 | TRIM28 | 2.21013244 |
| 11 | ZAK | 2.19200064 |
| 12 | PINK1 | 2.18396485 |
| 13 | GRK1 | 2.10562587 |
| 14 | BCKDK | 2.00758053 |
| 15 | NTRK2 | 1.99998098 |
| 16 | CAMKK1 | 1.98283453 |
| 17 | WNK4 | 1.86199804 |
| 18 | DYRK2 | 1.81211721 |
| 19 | EIF2AK1 | 1.79836935 |
| 20 | BMPR1B | 1.69280205 |
| 21 | STK16 | 1.56327579 |
| 22 | CAMKK2 | 1.55816943 |
| 23 | PTK6 | 1.52311977 |
| 24 | EPHB2 | 1.50355913 |
| 25 | NUAK1 | 1.42691004 |
| 26 | PRKCH | 1.42101949 |
| 27 | PRKCG | 1.39871260 |
| 28 | FGFR4 | 1.37182423 |
| 29 | RPS6KA5 | 1.24147279 |
| 30 | TIE1 | 1.20863281 |
| 31 | MINK1 | 1.15421619 |
| 32 | IKBKE | 1.12387495 |
| 33 | EIF2AK3 | 1.11831591 |
| 34 | PAK3 | 1.11606981 |
| 35 | FRK | 1.04653817 |
| 36 | ADRBK1 | 1.01949036 |
| 37 | IRAK1 | 0.97632178 |
| 38 | ITK | 0.95728119 |
| 39 | KIT | 0.94651336 |
| 40 | TEC | 0.92409663 |
| 41 | SGK223 | 0.90160863 |
| 42 | SGK494 | 0.90160863 |
| 43 | IKBKB | 0.88213987 |
| 44 | CDC7 | 0.84471529 |
| 45 | PRKCQ | 0.84219355 |
| 46 | PRKCE | 0.83915493 |
| 47 | TAF1 | 0.75799106 |
| 48 | CDK3 | 0.73273293 |
| 49 | SIK3 | 0.67462511 |
| 50 | ALK | 0.65918615 |
| 51 | BCR | 0.65704045 |
| 52 | SYK | 0.64234884 |
| 53 | SGK2 | 0.63473553 |
| 54 | CHUK | 0.62668690 |
| 55 | CAMK1 | 0.62491516 |
| 56 | MAP3K14 | 0.55999211 |
| 57 | VRK1 | 0.53613209 |
| 58 | CSNK1G2 | 0.53593164 |
| 59 | EPHA3 | 0.53226743 |
| 60 | EIF2AK2 | 0.53190300 |
| 61 | CSNK1E | 0.51487659 |
| 62 | TNIK | 0.50554793 |
| 63 | PRKCI | 0.49331109 |
| 64 | CSNK2A2 | 0.49035132 |
| 65 | AKT3 | 0.46494955 |
| 66 | PIK3CA | 0.46119963 |
| 67 | INSRR | 0.45918672 |
| 68 | RPS6KA6 | 0.45380743 |
| 69 | PRKCD | 0.45069080 |
| 70 | TGFBR1 | 0.44893923 |
| 71 | PIM2 | 0.44011842 |
| 72 | TGFBR2 | 0.43032288 |
| 73 | SIK2 | 0.41994623 |
| 74 | PRKCA | 0.41367460 |
| 75 | PLK2 | 0.39265205 |
| 76 | PRKACA | 0.39061443 |
| 77 | TYK2 | 0.38635333 |
| 78 | MAPK3 | 0.37128230 |
| 79 | NTRK3 | 0.36869318 |
| 80 | CAMK2A | 0.36318967 |
| 81 | OXSR1 | 0.36147586 |
| 82 | RPS6KA1 | 0.34321833 |
| 83 | PRKCB | 0.33496161 |
| 84 | STK4 | 0.33042763 |
| 85 | PRKCZ | 0.32563570 |
| 86 | OBSCN | 0.32441916 |
| 87 | NEK9 | 0.31313894 |
| 88 | LYN | 0.31033090 |
| 89 | ERN1 | 0.30818552 |
| 90 | SGK1 | 0.30471988 |
| 91 | CSNK1A1 | 0.30004265 |
| 92 | RPS6KC1 | 0.29702794 |
| 93 | RPS6KL1 | 0.29702794 |
| 94 | PRKACG | 0.29566940 |
| 95 | TAOK2 | 0.29537942 |
| 96 | CSNK2A1 | 0.28271072 |
| 97 | WNK3 | 0.28262301 |
| 98 | ATR | 0.28148251 |
| 99 | PRKG1 | 0.27902461 |
| 100 | SGK3 | 0.26638740 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.11663618 |
| 2 | One carbon pool by folate_Homo sapiens_hsa00670 | 3.51297716 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.30170181 |
| 4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.18899371 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.03629317 |
| 6 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.53141756 |
| 7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.38087049 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.01661207 |
| 9 | Phototransduction_Homo sapiens_hsa04744 | 1.97697931 |
| 10 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.94053002 |
| 11 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.93181994 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.92893936 |
| 13 | RNA degradation_Homo sapiens_hsa03018 | 1.92356513 |
| 14 | Proteasome_Homo sapiens_hsa03050 | 1.81920775 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.81233004 |
| 16 | Sulfur relay system_Homo sapiens_hsa04122 | 1.80275017 |
| 17 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.75164270 |
| 18 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.71353544 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.71236775 |
| 20 | RNA polymerase_Homo sapiens_hsa03020 | 1.67573025 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.62684294 |
| 22 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.59629975 |
| 23 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.53629005 |
| 24 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.53323070 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.49604352 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.45398797 |
| 27 | Allograft rejection_Homo sapiens_hsa05330 | 1.44577816 |
| 28 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.42708300 |
| 29 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.37031256 |
| 30 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.36799126 |
| 31 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.35250760 |
| 32 | Asthma_Homo sapiens_hsa05310 | 1.33928944 |
| 33 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.30250627 |
| 34 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.30209370 |
| 35 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.29247663 |
| 36 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.27676385 |
| 37 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.23935338 |
| 38 | Nicotine addiction_Homo sapiens_hsa05033 | 1.16837929 |
| 39 | Peroxisome_Homo sapiens_hsa04146 | 1.16177399 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.11258654 |
| 41 | Homologous recombination_Homo sapiens_hsa03440 | 1.09145577 |
| 42 | Protein export_Homo sapiens_hsa03060 | 1.07321203 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.04375548 |
| 44 | Olfactory transduction_Homo sapiens_hsa04740 | 1.03561062 |
| 45 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.02880187 |
| 46 | Morphine addiction_Homo sapiens_hsa05032 | 1.01837454 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.01404370 |
| 48 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.00914795 |
| 49 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.99109801 |
| 50 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.94514746 |
| 51 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93553272 |
| 52 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.91592244 |
| 53 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.85218572 |
| 54 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.85176660 |
| 55 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.84561041 |
| 56 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.83580826 |
| 57 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82698814 |
| 58 | Basal transcription factors_Homo sapiens_hsa03022 | 0.80418359 |
| 59 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.75539593 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.75409148 |
| 61 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74361601 |
| 62 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.73452394 |
| 63 | GABAergic synapse_Homo sapiens_hsa04727 | 0.67193410 |
| 64 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.66985718 |
| 65 | Taste transduction_Homo sapiens_hsa04742 | 0.66348253 |
| 66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65028383 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.62510993 |
| 68 | RNA transport_Homo sapiens_hsa03013 | 0.62063221 |
| 69 | Purine metabolism_Homo sapiens_hsa00230 | 0.60738345 |
| 70 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59013538 |
| 71 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.56420587 |
| 72 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.54627536 |
| 73 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.53929086 |
| 74 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.51238279 |
| 75 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.50398797 |
| 76 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.50103410 |
| 77 | Insulin secretion_Homo sapiens_hsa04911 | 0.47468771 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.45864016 |
| 79 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.44896272 |
| 80 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.42199184 |
| 81 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.39008119 |
| 82 | Mineral absorption_Homo sapiens_hsa04978 | 0.36642456 |
| 83 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.34962890 |
| 84 | Spliceosome_Homo sapiens_hsa03040 | 0.34626098 |
| 85 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.34000099 |
| 86 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.31578827 |
| 87 | Alcoholism_Homo sapiens_hsa05034 | 0.30765338 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30352626 |
| 89 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27792443 |
| 90 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.26591950 |
| 91 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.25370982 |
| 92 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.23834555 |
| 93 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.22413359 |
| 94 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.20797765 |
| 95 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.20742029 |
| 96 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.20044673 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.18712419 |
| 98 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.18700702 |
| 99 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.18191554 |
| 100 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.17390684 |

