

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 6.57187176 |
| 2 | translational termination (GO:0006415) | 6.29465863 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 5.98926534 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 5.69363599 |
| 5 | ATP synthesis coupled proton transport (GO:0015986) | 5.62461858 |
| 6 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.62461858 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.58287276 |
| 8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.57673059 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 5.50693536 |
| 10 | protein targeting to ER (GO:0045047) | 5.48740693 |
| 11 | translational elongation (GO:0006414) | 5.27475717 |
| 12 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 5.24292273 |
| 13 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.20791158 |
| 14 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.19431516 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 5.12747926 |
| 16 | behavioral response to nicotine (GO:0035095) | 4.99058118 |
| 17 | ribosomal large subunit biogenesis (GO:0042273) | 4.69638536 |
| 18 | cellular protein complex disassembly (GO:0043624) | 4.68214717 |
| 19 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.65263346 |
| 20 | viral life cycle (GO:0019058) | 4.62136512 |
| 21 | GTP biosynthetic process (GO:0006183) | 4.59150341 |
| 22 | respiratory electron transport chain (GO:0022904) | 4.49284825 |
| 23 | electron transport chain (GO:0022900) | 4.45613362 |
| 24 | DNA deamination (GO:0045006) | 4.34806222 |
| 25 | translational initiation (GO:0006413) | 4.28731916 |
| 26 | ribosomal small subunit biogenesis (GO:0042274) | 4.27875519 |
| 27 | peptidyl-histidine modification (GO:0018202) | 4.27262413 |
| 28 | protein complex biogenesis (GO:0070271) | 4.17840390 |
| 29 | gonadal mesoderm development (GO:0007506) | 4.15316647 |
| 30 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.97051289 |
| 31 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.96017555 |
| 32 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.96017555 |
| 33 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.94437223 |
| 34 | protein complex disassembly (GO:0043241) | 3.93632498 |
| 35 | translation (GO:0006412) | 3.90296045 |
| 36 | UTP biosynthetic process (GO:0006228) | 3.84024142 |
| 37 | protein neddylation (GO:0045116) | 3.82064860 |
| 38 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.79679958 |
| 39 | maturation of SSU-rRNA (GO:0030490) | 3.76965913 |
| 40 | UTP metabolic process (GO:0046051) | 3.67029715 |
| 41 | macromolecular complex disassembly (GO:0032984) | 3.66998940 |
| 42 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.61267319 |
| 43 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.57795913 |
| 44 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.55835550 |
| 45 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.54213116 |
| 46 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.49422272 |
| 47 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.49422272 |
| 48 | NADH dehydrogenase complex assembly (GO:0010257) | 3.49422272 |
| 49 | positive regulation of protein homooligomerization (GO:0032464) | 3.49070234 |
| 50 | protein targeting to membrane (GO:0006612) | 3.48399335 |
| 51 | mRNA catabolic process (GO:0006402) | 3.39657910 |
| 52 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.35669184 |
| 53 | protein-cofactor linkage (GO:0018065) | 3.33324883 |
| 54 | ATP biosynthetic process (GO:0006754) | 3.30356890 |
| 55 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.29196748 |
| 56 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.25112985 |
| 57 | cell proliferation in forebrain (GO:0021846) | 3.23458817 |
| 58 | hydrogen ion transmembrane transport (GO:1902600) | 3.20658647 |
| 59 | RNA catabolic process (GO:0006401) | 3.17091638 |
| 60 | CTP metabolic process (GO:0046036) | 3.14916660 |
| 61 | CTP biosynthetic process (GO:0006241) | 3.14916660 |
| 62 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.10529550 |
| 63 | aldehyde catabolic process (GO:0046185) | 3.03515990 |
| 64 | nucleoside diphosphate phosphorylation (GO:0006165) | 3.02532070 |
| 65 | cellular response to interferon-beta (GO:0035458) | 3.00377972 |
| 66 | regulation of oxidative phosphorylation (GO:0002082) | 2.99220071 |
| 67 | cellular component biogenesis (GO:0044085) | 2.98726988 |
| 68 | axoneme assembly (GO:0035082) | 2.97782798 |
| 69 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.92581528 |
| 70 | proton transport (GO:0015992) | 2.89236780 |
| 71 | hydrogen transport (GO:0006818) | 2.88006300 |
| 72 | left/right axis specification (GO:0070986) | 2.87972864 |
| 73 | rRNA modification (GO:0000154) | 2.83920774 |
| 74 | ubiquinone biosynthetic process (GO:0006744) | 2.80576507 |
| 75 | rRNA catabolic process (GO:0016075) | 2.79063957 |
| 76 | nonmotile primary cilium assembly (GO:0035058) | 2.78529484 |
| 77 | epithelial cilium movement (GO:0003351) | 2.78056350 |
| 78 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.75999209 |
| 79 | axonemal dynein complex assembly (GO:0070286) | 2.74773397 |
| 80 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.74500418 |
| 81 | pseudouridine synthesis (GO:0001522) | 2.73224648 |
| 82 | indolalkylamine metabolic process (GO:0006586) | 2.71929900 |
| 83 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.71701493 |
| 84 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.70569333 |
| 85 | cytochrome complex assembly (GO:0017004) | 2.69862461 |
| 86 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.69556543 |
| 87 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.68671833 |
| 88 | respiratory chain complex IV assembly (GO:0008535) | 2.68456814 |
| 89 | neural tube formation (GO:0001841) | 2.67694673 |
| 90 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.67326592 |
| 91 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.62220797 |
| 92 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.62097983 |
| 93 | negative regulation of response to food (GO:0032096) | 2.60957333 |
| 94 | negative regulation of appetite (GO:0032099) | 2.60957333 |
| 95 | intracellular protein transmembrane import (GO:0044743) | 2.60354260 |
| 96 | proteasome assembly (GO:0043248) | 2.59218568 |
| 97 | rRNA metabolic process (GO:0016072) | 2.58156387 |
| 98 | ubiquinone metabolic process (GO:0006743) | 2.56052786 |
| 99 | positive regulation of prostaglandin secretion (GO:0032308) | 2.54391610 |
| 100 | rRNA processing (GO:0006364) | 2.53196583 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.99936588 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.92360009 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.58180541 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.24209965 |
| 5 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.11808959 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.07540765 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.02053140 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.72521854 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.53645087 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.44151377 |
| 11 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.41386986 |
| 12 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.33887232 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.32453828 |
| 14 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.31342615 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.18572538 |
| 16 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.09647457 |
| 17 | TP53_22573176_ChIP-Seq_HFKS_Human | 2.06732801 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.05929961 |
| 19 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 2.02355980 |
| 20 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.94573615 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91975358 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.89243503 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.86110704 |
| 24 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.83649843 |
| 25 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.78385676 |
| 26 | VDR_22108803_ChIP-Seq_LS180_Human | 1.76965298 |
| 27 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.62076313 |
| 28 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.57527729 |
| 29 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.57261263 |
| 30 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.55074948 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.54406175 |
| 32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.52495767 |
| 33 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.52038033 |
| 34 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.51433145 |
| 35 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.51312475 |
| 36 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.47507384 |
| 37 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.47507384 |
| 38 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.45199718 |
| 39 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.44043328 |
| 40 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.43420380 |
| 41 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.40886702 |
| 42 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.40715967 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.38050388 |
| 44 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.36197997 |
| 45 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.33669694 |
| 46 | EWS_26573619_Chip-Seq_HEK293_Human | 1.32032412 |
| 47 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.28336023 |
| 48 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.26524897 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.24355888 |
| 50 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.22193940 |
| 51 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.21845358 |
| 52 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.19240568 |
| 53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.16893652 |
| 54 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.15844474 |
| 55 | NCOR_22424771_ChIP-Seq_293T_Human | 1.14450328 |
| 56 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.14444602 |
| 57 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.14298026 |
| 58 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.12161148 |
| 59 | P300_19829295_ChIP-Seq_ESCs_Human | 1.11589865 |
| 60 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.10599729 |
| 61 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.10599729 |
| 62 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.10069149 |
| 63 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.08878854 |
| 64 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.08863135 |
| 65 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.08791063 |
| 66 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.08630678 |
| 67 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.07193739 |
| 68 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.06057695 |
| 69 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.05921775 |
| 70 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.05820099 |
| 71 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04620751 |
| 72 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.02365154 |
| 73 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.01572188 |
| 74 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.99698558 |
| 75 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99443557 |
| 76 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99443557 |
| 77 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.97681954 |
| 78 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.96859977 |
| 79 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96641985 |
| 80 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.96345267 |
| 81 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96341783 |
| 82 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95579787 |
| 83 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.95135215 |
| 84 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94506390 |
| 85 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.93565170 |
| 86 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.93233308 |
| 87 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.93146932 |
| 88 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.91281039 |
| 89 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.91101294 |
| 90 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.90251333 |
| 91 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.90033962 |
| 92 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89222823 |
| 93 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.89090166 |
| 94 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.89047032 |
| 95 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.88233405 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.87005925 |
| 97 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.86332500 |
| 98 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.86033574 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.85807816 |
| 100 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.85726751 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.22504552 |
| 2 | MP0006292_abnormal_olfactory_placode | 4.48751240 |
| 3 | MP0003787_abnormal_imprinting | 4.22989187 |
| 4 | MP0005360_urolithiasis | 3.27385429 |
| 5 | MP0008877_abnormal_DNA_methylation | 2.89683498 |
| 6 | MP0002837_dystrophic_cardiac_calcinosis | 2.79024497 |
| 7 | MP0003121_genomic_imprinting | 2.53405390 |
| 8 | MP0000372_irregular_coat_pigmentation | 2.51676501 |
| 9 | MP0001348_abnormal_lacrimal_gland | 2.45484617 |
| 10 | MP0002163_abnormal_gland_morphology | 2.45023380 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.33062887 |
| 12 | MP0003123_paternal_imprinting | 2.20781410 |
| 13 | MP0008875_abnormal_xenobiotic_pharmacok | 2.20373134 |
| 14 | MP0005379_endocrine/exocrine_gland_phen | 2.10277576 |
| 15 | MP0002102_abnormal_ear_morphology | 2.04742790 |
| 16 | MP0008789_abnormal_olfactory_epithelium | 1.95833970 |
| 17 | MP0008872_abnormal_physiological_respon | 1.95513394 |
| 18 | MP0005646_abnormal_pituitary_gland | 1.93766090 |
| 19 | MP0003195_calcinosis | 1.81645306 |
| 20 | MP0003122_maternal_imprinting | 1.78971418 |
| 21 | MP0003252_abnormal_bile_duct | 1.74402289 |
| 22 | MP0002653_abnormal_ependyma_morphology | 1.64115054 |
| 23 | MP0005377_hearing/vestibular/ear_phenot | 1.64105956 |
| 24 | MP0003878_abnormal_ear_physiology | 1.64105956 |
| 25 | MP0005075_abnormal_melanosome_morpholog | 1.63680233 |
| 26 | MP0002160_abnormal_reproductive_system | 1.59718941 |
| 27 | MP0005394_taste/olfaction_phenotype | 1.52041478 |
| 28 | MP0005499_abnormal_olfactory_system | 1.52041478 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.49000235 |
| 30 | MP0004142_abnormal_muscle_tone | 1.44643915 |
| 31 | MP0001984_abnormal_olfaction | 1.44408923 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.40596147 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.37970883 |
| 34 | MP0003011_delayed_dark_adaptation | 1.37775671 |
| 35 | MP0005389_reproductive_system_phenotype | 1.37390574 |
| 36 | MP0001293_anophthalmia | 1.34702286 |
| 37 | MP0004043_abnormal_pH_regulation | 1.34613472 |
| 38 | MP0006072_abnormal_retinal_apoptosis | 1.33254045 |
| 39 | MP0001905_abnormal_dopamine_level | 1.32071637 |
| 40 | MP0003646_muscle_fatigue | 1.28859614 |
| 41 | MP0000049_abnormal_middle_ear | 1.25492528 |
| 42 | MP0002234_abnormal_pharynx_morphology | 1.24743846 |
| 43 | MP0001835_abnormal_antigen_presentation | 1.24271169 |
| 44 | MP0003136_yellow_coat_color | 1.22339287 |
| 45 | MP0002928_abnormal_bile_duct | 1.21964364 |
| 46 | MP0006276_abnormal_autonomic_nervous | 1.20726879 |
| 47 | MP0009764_decreased_sensitivity_to | 1.20062775 |
| 48 | MP0002272_abnormal_nervous_system | 1.18973269 |
| 49 | MP0002736_abnormal_nociception_after | 1.18361763 |
| 50 | MP0001986_abnormal_taste_sensitivity | 1.15059967 |
| 51 | MP0003186_abnormal_redox_activity | 1.14790764 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 1.14777863 |
| 53 | MP0005551_abnormal_eye_electrophysiolog | 1.13540851 |
| 54 | MP0003315_abnormal_perineum_morphology | 1.13155389 |
| 55 | MP0003718_maternal_effect | 1.10545982 |
| 56 | MP0005253_abnormal_eye_physiology | 1.07931103 |
| 57 | MP0006082_CNS_inflammation | 1.07488986 |
| 58 | MP0001529_abnormal_vocalization | 1.05546824 |
| 59 | MP0004147_increased_porphyrin_level | 1.04174608 |
| 60 | MP0001873_stomach_inflammation | 1.01437656 |
| 61 | MP0009046_muscle_twitch | 1.00464733 |
| 62 | MP0000685_abnormal_immune_system | 1.00055992 |
| 63 | MP0001970_abnormal_pain_threshold | 0.99795747 |
| 64 | MP0002095_abnormal_skin_pigmentation | 0.98835947 |
| 65 | MP0009745_abnormal_behavioral_response | 0.94056978 |
| 66 | MP0008058_abnormal_DNA_repair | 0.92518015 |
| 67 | MP0002733_abnormal_thermal_nociception | 0.91200305 |
| 68 | MP0005645_abnormal_hypothalamus_physiol | 0.86079292 |
| 69 | MP0001756_abnormal_urination | 0.84548289 |
| 70 | MP0005332_abnormal_amino_acid | 0.83842761 |
| 71 | MP0001919_abnormal_reproductive_system | 0.83265212 |
| 72 | MP0000631_abnormal_neuroendocrine_gland | 0.82689028 |
| 73 | MP0004885_abnormal_endolymph | 0.81918359 |
| 74 | MP0002277_abnormal_respiratory_mucosa | 0.81844444 |
| 75 | MP0002557_abnormal_social/conspecific_i | 0.80160495 |
| 76 | MP0004019_abnormal_vitamin_homeostasis | 0.78985040 |
| 77 | MP0005410_abnormal_fertilization | 0.78202545 |
| 78 | MP0001501_abnormal_sleep_pattern | 0.75278952 |
| 79 | MP0002148_abnormal_hypersensitivity_rea | 0.74543098 |
| 80 | MP0002233_abnormal_nose_morphology | 0.74162182 |
| 81 | MP0000230_abnormal_systemic_arterial | 0.73934294 |
| 82 | MP0005195_abnormal_posterior_eye | 0.72847094 |
| 83 | MP0008775_abnormal_heart_ventricle | 0.71874970 |
| 84 | MP0001663_abnormal_digestive_system | 0.71784685 |
| 85 | MP0005671_abnormal_response_to | 0.70211078 |
| 86 | MP0003638_abnormal_response/metabolism_ | 0.69947514 |
| 87 | MP0002693_abnormal_pancreas_physiology | 0.68558784 |
| 88 | MP0005386_behavior/neurological_phenoty | 0.68318537 |
| 89 | MP0004924_abnormal_behavior | 0.68318537 |
| 90 | MP0000613_abnormal_salivary_gland | 0.68203313 |
| 91 | MP0002210_abnormal_sex_determination | 0.68034933 |
| 92 | MP0002138_abnormal_hepatobiliary_system | 0.67099886 |
| 93 | MP0006036_abnormal_mitochondrial_physio | 0.65282161 |
| 94 | MP0009333_abnormal_splenocyte_physiolog | 0.65273691 |
| 95 | MP0001764_abnormal_homeostasis | 0.64496500 |
| 96 | MP0005636_abnormal_mineral_homeostasis | 0.63385898 |
| 97 | MP0001790_abnormal_immune_system | 0.62827897 |
| 98 | MP0005387_immune_system_phenotype | 0.62827897 |
| 99 | MP0005408_hypopigmentation | 0.61816100 |
| 100 | MP0002752_abnormal_somatic_nervous | 0.61757062 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.73615121 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.55449464 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.23761415 |
| 4 | Increased CSF lactate (HP:0002490) | 4.14853349 |
| 5 | Acute encephalopathy (HP:0006846) | 4.05232223 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.03285040 |
| 7 | Progressive macrocephaly (HP:0004481) | 3.82259553 |
| 8 | Lipid accumulation in hepatocytes (HP:0006561) | 3.71128546 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.61011030 |
| 10 | Hepatic necrosis (HP:0002605) | 3.50824547 |
| 11 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.24320128 |
| 12 | Medial flaring of the eyebrow (HP:0010747) | 3.22201938 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.18712349 |
| 14 | Abnormality of midbrain morphology (HP:0002418) | 3.18712349 |
| 15 | Large for gestational age (HP:0001520) | 3.18575518 |
| 16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.18258274 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.18203550 |
| 18 | Cerebral edema (HP:0002181) | 3.06064448 |
| 19 | Pancreatic fibrosis (HP:0100732) | 2.98834701 |
| 20 | Optic disc pallor (HP:0000543) | 2.97576631 |
| 21 | 3-Methylglutaconic aciduria (HP:0003535) | 2.93340894 |
| 22 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.91581241 |
| 23 | Increased intramyocellular lipid droplets (HP:0012240) | 2.89305092 |
| 24 | Pancreatic cysts (HP:0001737) | 2.86963685 |
| 25 | Nephronophthisis (HP:0000090) | 2.79537842 |
| 26 | Septo-optic dysplasia (HP:0100842) | 2.70490159 |
| 27 | Sclerocornea (HP:0000647) | 2.68346817 |
| 28 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.68094347 |
| 29 | Lactic acidosis (HP:0003128) | 2.65839202 |
| 30 | Exertional dyspnea (HP:0002875) | 2.64693583 |
| 31 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.63140747 |
| 32 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.62387676 |
| 33 | Abnormality of renal resorption (HP:0011038) | 2.58878944 |
| 34 | Abnormal number of erythroid precursors (HP:0012131) | 2.56094770 |
| 35 | Congenital, generalized hypertrichosis (HP:0004540) | 2.53941095 |
| 36 | Macrocytic anemia (HP:0001972) | 2.53809600 |
| 37 | Increased serum lactate (HP:0002151) | 2.52941076 |
| 38 | Reticulocytopenia (HP:0001896) | 2.52787099 |
| 39 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.49042060 |
| 40 | True hermaphroditism (HP:0010459) | 2.45581185 |
| 41 | Limb dystonia (HP:0002451) | 2.44894852 |
| 42 | Abnormal ciliary motility (HP:0012262) | 2.42590146 |
| 43 | Gait imbalance (HP:0002141) | 2.41434801 |
| 44 | Congenital primary aphakia (HP:0007707) | 2.40030695 |
| 45 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.38381250 |
| 46 | Increased muscle lipid content (HP:0009058) | 2.37134904 |
| 47 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.36805390 |
| 48 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.36805390 |
| 49 | Respiratory difficulties (HP:0002880) | 2.32377333 |
| 50 | Nephrogenic diabetes insipidus (HP:0009806) | 2.29958477 |
| 51 | Abnormality of the renal medulla (HP:0100957) | 2.25800631 |
| 52 | Congenital stationary night blindness (HP:0007642) | 2.23886602 |
| 53 | Leukodystrophy (HP:0002415) | 2.22484547 |
| 54 | Respiratory failure (HP:0002878) | 2.20387156 |
| 55 | Constricted visual fields (HP:0001133) | 2.20110553 |
| 56 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.19866688 |
| 57 | Absent/shortened dynein arms (HP:0200106) | 2.19866688 |
| 58 | Abnormality of alanine metabolism (HP:0010916) | 2.17522906 |
| 59 | Hyperalaninemia (HP:0003348) | 2.17522906 |
| 60 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.17522906 |
| 61 | Exercise intolerance (HP:0003546) | 2.15526678 |
| 62 | Abnormality of T cell physiology (HP:0011840) | 2.10811519 |
| 63 | Pendular nystagmus (HP:0012043) | 2.05608503 |
| 64 | Abnormality of the renal cortex (HP:0011035) | 2.05359729 |
| 65 | Stenosis of the external auditory canal (HP:0000402) | 2.04492712 |
| 66 | Pallor (HP:0000980) | 2.04150048 |
| 67 | Rib fusion (HP:0000902) | 2.00024778 |
| 68 | Lethargy (HP:0001254) | 1.99778190 |
| 69 | Colon cancer (HP:0003003) | 1.97837892 |
| 70 | Absent thumb (HP:0009777) | 1.97511417 |
| 71 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.97453335 |
| 72 | Abnormality of urine glucose concentration (HP:0011016) | 1.96555271 |
| 73 | Glycosuria (HP:0003076) | 1.96555271 |
| 74 | Hypothermia (HP:0002045) | 1.95923567 |
| 75 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.94702725 |
| 76 | Chronic hepatic failure (HP:0100626) | 1.94010682 |
| 77 | Decreased central vision (HP:0007663) | 1.92992008 |
| 78 | X-linked dominant inheritance (HP:0001423) | 1.92803918 |
| 79 | Attenuation of retinal blood vessels (HP:0007843) | 1.91790915 |
| 80 | Asplenia (HP:0001746) | 1.91445117 |
| 81 | Type I transferrin isoform profile (HP:0003642) | 1.91412275 |
| 82 | Abnormal hemoglobin (HP:0011902) | 1.89624856 |
| 83 | Abolished electroretinogram (ERG) (HP:0000550) | 1.89315269 |
| 84 | Renal cortical cysts (HP:0000803) | 1.88059318 |
| 85 | Anencephaly (HP:0002323) | 1.86700574 |
| 86 | Progressive cerebellar ataxia (HP:0002073) | 1.85331398 |
| 87 | Hyperphosphaturia (HP:0003109) | 1.84429317 |
| 88 | Absent septum pellucidum (HP:0001331) | 1.84309620 |
| 89 | Rhinitis (HP:0012384) | 1.82648260 |
| 90 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.82524534 |
| 91 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.82524534 |
| 92 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.80116180 |
| 93 | Type II lissencephaly (HP:0007260) | 1.79808425 |
| 94 | Cystic liver disease (HP:0006706) | 1.79255902 |
| 95 | Growth hormone deficiency (HP:0000824) | 1.79210490 |
| 96 | Chronic bronchitis (HP:0004469) | 1.77912752 |
| 97 | Cleft eyelid (HP:0000625) | 1.77426920 |
| 98 | Occipital encephalocele (HP:0002085) | 1.76312295 |
| 99 | Abnormal drinking behavior (HP:0030082) | 1.75332097 |
| 100 | Polydipsia (HP:0001959) | 1.75332097 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 4.99328174 |
| 2 | BMPR1B | 4.21046307 |
| 3 | WNK4 | 3.06399853 |
| 4 | CDK19 | 2.73183384 |
| 5 | BCKDK | 2.61184530 |
| 6 | ADRBK2 | 2.28688659 |
| 7 | CDK8 | 2.22353171 |
| 8 | TNK2 | 2.09640484 |
| 9 | GRK1 | 2.05205232 |
| 10 | NUAK1 | 2.02439344 |
| 11 | TAOK3 | 1.88751699 |
| 12 | ZAK | 1.82060236 |
| 13 | FRK | 1.71568747 |
| 14 | TGFBR1 | 1.67250783 |
| 15 | NEK1 | 1.65175035 |
| 16 | VRK2 | 1.62495620 |
| 17 | OXSR1 | 1.58598132 |
| 18 | NME2 | 1.54573185 |
| 19 | STK39 | 1.52162728 |
| 20 | LIMK1 | 1.50982925 |
| 21 | DYRK2 | 1.46428717 |
| 22 | MAP2K6 | 1.42372493 |
| 23 | WNK3 | 1.34939291 |
| 24 | TXK | 1.32679387 |
| 25 | PIM2 | 1.25074885 |
| 26 | PBK | 1.22394837 |
| 27 | EPHB2 | 1.20554794 |
| 28 | TIE1 | 1.19700314 |
| 29 | TAF1 | 1.17947046 |
| 30 | MKNK1 | 1.17387455 |
| 31 | ABL2 | 1.15396167 |
| 32 | TLK1 | 1.12144176 |
| 33 | PINK1 | 1.11886294 |
| 34 | SRPK1 | 1.08744527 |
| 35 | PIK3CA | 1.06771359 |
| 36 | BCR | 1.04597186 |
| 37 | CASK | 1.04441092 |
| 38 | PHKG1 | 1.01738993 |
| 39 | PHKG2 | 1.01738993 |
| 40 | BMPR2 | 0.88715159 |
| 41 | TNIK | 0.86515096 |
| 42 | ADRBK1 | 0.85438519 |
| 43 | PRKCG | 0.84945967 |
| 44 | MAP3K4 | 0.84659755 |
| 45 | PRKCQ | 0.83466372 |
| 46 | ITK | 0.81816207 |
| 47 | TEC | 0.79609475 |
| 48 | RPS6KA5 | 0.77968620 |
| 49 | CSF1R | 0.75650729 |
| 50 | INSRR | 0.73543707 |
| 51 | NME1 | 0.72811445 |
| 52 | IKBKB | 0.70865515 |
| 53 | PDK2 | 0.70263237 |
| 54 | VRK1 | 0.69926910 |
| 55 | PRKD3 | 0.66563194 |
| 56 | CDK9 | 0.65674016 |
| 57 | KIT | 0.64554755 |
| 58 | DYRK1B | 0.64333617 |
| 59 | LYN | 0.64034314 |
| 60 | FLT3 | 0.63683970 |
| 61 | PASK | 0.62945823 |
| 62 | PLK1 | 0.62745144 |
| 63 | PLK4 | 0.62398396 |
| 64 | MAP2K7 | 0.62201398 |
| 65 | DAPK3 | 0.60519001 |
| 66 | ACVR1B | 0.59887753 |
| 67 | MAPKAPK5 | 0.59582293 |
| 68 | FES | 0.58983381 |
| 69 | RPS6KA6 | 0.56511801 |
| 70 | BTK | 0.56001387 |
| 71 | SYK | 0.55842733 |
| 72 | CHEK2 | 0.54577967 |
| 73 | STK38L | 0.53750456 |
| 74 | CSNK1G2 | 0.53591912 |
| 75 | AURKB | 0.52692826 |
| 76 | STK11 | 0.52005588 |
| 77 | PTK6 | 0.51254333 |
| 78 | CDK3 | 0.50264848 |
| 79 | MAPK15 | 0.50190522 |
| 80 | CSNK1G3 | 0.50022091 |
| 81 | NTRK2 | 0.49674330 |
| 82 | CSNK2A2 | 0.49126761 |
| 83 | CSNK2A1 | 0.48257043 |
| 84 | PRKACA | 0.47895656 |
| 85 | MAP4K1 | 0.47487696 |
| 86 | CAMK1 | 0.46623905 |
| 87 | GRK6 | 0.45721454 |
| 88 | EIF2AK3 | 0.45383296 |
| 89 | IKBKE | 0.44978431 |
| 90 | DYRK1A | 0.44159249 |
| 91 | PLK3 | 0.41824746 |
| 92 | MKNK2 | 0.40574390 |
| 93 | CAMKK2 | 0.40151729 |
| 94 | CSNK1G1 | 0.39854587 |
| 95 | RPS6KC1 | 0.39420543 |
| 96 | RPS6KL1 | 0.39420543 |
| 97 | MARK3 | 0.38339583 |
| 98 | DAPK2 | 0.37195611 |
| 99 | ATR | 0.36700497 |
| 100 | EPHA4 | 0.36339040 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.25376050 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.21864345 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.73222091 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.04186849 |
| 5 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.56139432 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.53158445 |
| 7 | Huntingtons disease_Homo sapiens_hsa05016 | 2.51401896 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.45296018 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.24264172 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.18053341 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.15926283 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.15251706 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 2.12640987 |
| 14 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.11067180 |
| 15 | Homologous recombination_Homo sapiens_hsa03440 | 2.07067745 |
| 16 | Proteasome_Homo sapiens_hsa03050 | 1.86353481 |
| 17 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.84642511 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.82824114 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67065557 |
| 20 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.65929374 |
| 21 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.58417839 |
| 22 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.49585788 |
| 23 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.41074924 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37316923 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.31663783 |
| 26 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.31418722 |
| 27 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.29424225 |
| 28 | Base excision repair_Homo sapiens_hsa03410 | 1.23473512 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.21223553 |
| 30 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.19102248 |
| 31 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.17645393 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16189911 |
| 33 | Mismatch repair_Homo sapiens_hsa03430 | 1.14924377 |
| 34 | DNA replication_Homo sapiens_hsa03030 | 1.10776639 |
| 35 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.08033022 |
| 36 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.05241536 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.02101032 |
| 38 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.00262994 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 0.98969746 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.98731896 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.95011877 |
| 42 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93251772 |
| 43 | Spliceosome_Homo sapiens_hsa03040 | 0.93175454 |
| 44 | Olfactory transduction_Homo sapiens_hsa04740 | 0.87886171 |
| 45 | Retinol metabolism_Homo sapiens_hsa00830 | 0.87740973 |
| 46 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.84253455 |
| 47 | Phototransduction_Homo sapiens_hsa04744 | 0.84034511 |
| 48 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.82218246 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.80462774 |
| 50 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.79464481 |
| 51 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.77593335 |
| 52 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.74522531 |
| 53 | RNA transport_Homo sapiens_hsa03013 | 0.73194461 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71880689 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71756301 |
| 56 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.71604999 |
| 57 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68827453 |
| 58 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68790619 |
| 59 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.65288209 |
| 60 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63132778 |
| 61 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62259350 |
| 62 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.61286158 |
| 63 | Viral myocarditis_Homo sapiens_hsa05416 | 0.61285687 |
| 64 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.59573207 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.59186450 |
| 66 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.58487768 |
| 67 | Nicotine addiction_Homo sapiens_hsa05033 | 0.55290794 |
| 68 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.53806787 |
| 69 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.52416354 |
| 70 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.52198494 |
| 71 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.52121625 |
| 72 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50627553 |
| 73 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50444529 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.50224069 |
| 75 | Morphine addiction_Homo sapiens_hsa05032 | 0.50016161 |
| 76 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.48196201 |
| 77 | Salivary secretion_Homo sapiens_hsa04970 | 0.47688974 |
| 78 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.45612192 |
| 79 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.44575344 |
| 80 | Taste transduction_Homo sapiens_hsa04742 | 0.44200965 |
| 81 | Insulin secretion_Homo sapiens_hsa04911 | 0.43612044 |
| 82 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.41672524 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41061974 |
| 84 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.40853524 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40810771 |
| 86 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.36505147 |
| 87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.34109599 |
| 88 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.33483620 |
| 89 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.31656413 |
| 90 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29702803 |
| 91 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.29597606 |
| 92 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.29560029 |
| 93 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.26640800 |
| 94 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.24715957 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.24696631 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.23633436 |
| 97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.22776551 |
| 98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.20235456 |
| 99 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.20161998 |
| 100 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.16368697 |

