RPL30P7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.57187176
2translational termination (GO:0006415)6.29465863
3chaperone-mediated protein transport (GO:0072321)5.98926534
4ribosomal small subunit assembly (GO:0000028)5.69363599
5ATP synthesis coupled proton transport (GO:0015986)5.62461858
6energy coupled proton transport, down electrochemical gradient (GO:0015985)5.62461858
7establishment of protein localization to mitochondrial membrane (GO:0090151)5.58287276
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.57673059
9cotranslational protein targeting to membrane (GO:0006613)5.50693536
10protein targeting to ER (GO:0045047)5.48740693
11translational elongation (GO:0006414)5.27475717
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.24292273
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.20791158
14mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.19431516
15protein localization to endoplasmic reticulum (GO:0070972)5.12747926
16behavioral response to nicotine (GO:0035095)4.99058118
17ribosomal large subunit biogenesis (GO:0042273)4.69638536
18cellular protein complex disassembly (GO:0043624)4.68214717
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.65263346
20viral life cycle (GO:0019058)4.62136512
21GTP biosynthetic process (GO:0006183)4.59150341
22respiratory electron transport chain (GO:0022904)4.49284825
23electron transport chain (GO:0022900)4.45613362
24DNA deamination (GO:0045006)4.34806222
25translational initiation (GO:0006413)4.28731916
26ribosomal small subunit biogenesis (GO:0042274)4.27875519
27peptidyl-histidine modification (GO:0018202)4.27262413
28protein complex biogenesis (GO:0070271)4.17840390
29gonadal mesoderm development (GO:0007506)4.15316647
30exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.97051289
31RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.96017555
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.96017555
33nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.94437223
34protein complex disassembly (GO:0043241)3.93632498
35translation (GO:0006412)3.90296045
36UTP biosynthetic process (GO:0006228)3.84024142
37protein neddylation (GO:0045116)3.82064860
38mitochondrial respiratory chain complex assembly (GO:0033108)3.79679958
39maturation of SSU-rRNA (GO:0030490)3.76965913
40UTP metabolic process (GO:0046051)3.67029715
41macromolecular complex disassembly (GO:0032984)3.66998940
42purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.61267319
43nuclear-transcribed mRNA catabolic process (GO:0000956)3.57795913
44water-soluble vitamin biosynthetic process (GO:0042364)3.55835550
45purine nucleoside triphosphate biosynthetic process (GO:0009145)3.54213116
46mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.49422272
47mitochondrial respiratory chain complex I assembly (GO:0032981)3.49422272
48NADH dehydrogenase complex assembly (GO:0010257)3.49422272
49positive regulation of protein homooligomerization (GO:0032464)3.49070234
50protein targeting to membrane (GO:0006612)3.48399335
51mRNA catabolic process (GO:0006402)3.39657910
52negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.35669184
53protein-cofactor linkage (GO:0018065)3.33324883
54ATP biosynthetic process (GO:0006754)3.30356890
55epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.29196748
56preassembly of GPI anchor in ER membrane (GO:0016254)3.25112985
57cell proliferation in forebrain (GO:0021846)3.23458817
58hydrogen ion transmembrane transport (GO:1902600)3.20658647
59RNA catabolic process (GO:0006401)3.17091638
60CTP metabolic process (GO:0046036)3.14916660
61CTP biosynthetic process (GO:0006241)3.14916660
62ribonucleoside triphosphate biosynthetic process (GO:0009201)3.10529550
63aldehyde catabolic process (GO:0046185)3.03515990
64nucleoside diphosphate phosphorylation (GO:0006165)3.02532070
65cellular response to interferon-beta (GO:0035458)3.00377972
66regulation of oxidative phosphorylation (GO:0002082)2.99220071
67cellular component biogenesis (GO:0044085)2.98726988
68axoneme assembly (GO:0035082)2.97782798
69detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.92581528
70proton transport (GO:0015992)2.89236780
71hydrogen transport (GO:0006818)2.88006300
72left/right axis specification (GO:0070986)2.87972864
73rRNA modification (GO:0000154)2.83920774
74ubiquinone biosynthetic process (GO:0006744)2.80576507
75rRNA catabolic process (GO:0016075)2.79063957
76nonmotile primary cilium assembly (GO:0035058)2.78529484
77epithelial cilium movement (GO:0003351)2.78056350
78nucleoside triphosphate biosynthetic process (GO:0009142)2.75999209
79axonemal dynein complex assembly (GO:0070286)2.74773397
80ribonucleoprotein complex biogenesis (GO:0022613)2.74500418
81pseudouridine synthesis (GO:0001522)2.73224648
82indolalkylamine metabolic process (GO:0006586)2.71929900
83pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.71701493
84regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645)2.70569333
85cytochrome complex assembly (GO:0017004)2.69862461
86pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.69556543
87pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.68671833
88respiratory chain complex IV assembly (GO:0008535)2.68456814
89neural tube formation (GO:0001841)2.67694673
90guanosine-containing compound biosynthetic process (GO:1901070)2.67326592
91pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.62220797
92negative regulation of DNA-templated transcription, elongation (GO:0032785)2.62097983
93negative regulation of response to food (GO:0032096)2.60957333
94negative regulation of appetite (GO:0032099)2.60957333
95intracellular protein transmembrane import (GO:0044743)2.60354260
96proteasome assembly (GO:0043248)2.59218568
97rRNA metabolic process (GO:0016072)2.58156387
98ubiquinone metabolic process (GO:0006743)2.56052786
99positive regulation of prostaglandin secretion (GO:0032308)2.54391610
100rRNA processing (GO:0006364)2.53196583

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human3.99936588
2SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.92360009
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.58180541
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.24209965
5FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.11808959
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.07540765
7EZH2_22144423_ChIP-Seq_EOC_Human3.02053140
8ZNF274_21170338_ChIP-Seq_K562_Hela2.72521854
9ETS1_20019798_ChIP-Seq_JURKAT_Human2.53645087
10JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.44151377
11MYC_18555785_ChIP-Seq_MESCs_Mouse2.41386986
12EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human2.33887232
13ELK1_19687146_ChIP-ChIP_HELA_Human2.32453828
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.31342615
15VDR_23849224_ChIP-Seq_CD4+_Human2.18572538
16IRF1_19129219_ChIP-ChIP_H3396_Human2.09647457
17TP53_22573176_ChIP-Seq_HFKS_Human2.06732801
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.05929961
19CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.02355980
20CREB1_15753290_ChIP-ChIP_HEK293T_Human1.94573615
21FOXP3_21729870_ChIP-Seq_TREG_Human1.91975358
22FLI1_27457419_Chip-Seq_LIVER_Mouse1.89243503
23ELF1_17652178_ChIP-ChIP_JURKAT_Human1.86110704
24SRF_21415370_ChIP-Seq_HL-1_Mouse1.83649843
25TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.78385676
26VDR_22108803_ChIP-Seq_LS180_Human1.76965298
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.62076313
28PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.57527729
29MYC_18358816_ChIP-ChIP_MESCs_Mouse1.57261263
30IGF1R_20145208_ChIP-Seq_DFB_Human1.55074948
31FUS_26573619_Chip-Seq_HEK293_Human1.54406175
32TTF2_22483619_ChIP-Seq_HELA_Human1.52495767
33MYC_18940864_ChIP-ChIP_HL60_Human1.52038033
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.51433145
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.51312475
36FOXA1_27270436_Chip-Seq_PROSTATE_Human1.47507384
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.47507384
38GATA3_21878914_ChIP-Seq_MCF-7_Human1.45199718
39CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.44043328
40BCAT_22108803_ChIP-Seq_LS180_Human1.43420380
41E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40886702
42PCGF2_27294783_Chip-Seq_ESCs_Mouse1.40715967
43GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.38050388
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.36197997
45ETV2_25802403_ChIP-Seq_MESCs_Mouse1.33669694
46EWS_26573619_Chip-Seq_HEK293_Human1.32032412
47BMI1_23680149_ChIP-Seq_NPCS_Mouse1.28336023
48CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.26524897
49GABP_19822575_ChIP-Seq_HepG2_Human1.24355888
50TAF15_26573619_Chip-Seq_HEK293_Human1.22193940
51PCGF2_27294783_Chip-Seq_NPCs_Mouse1.21845358
52ERG_20517297_ChIP-Seq_VCAP_Human1.19240568
53GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.16893652
54AUTS2_25519132_ChIP-Seq_293T-REX_Human1.15844474
55NCOR_22424771_ChIP-Seq_293T_Human1.14450328
56FOXH1_21741376_ChIP-Seq_EPCs_Human1.14444602
57CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.14298026
58GATA6_21074721_ChIP-Seq_CACO-2_Human1.12161148
59P300_19829295_ChIP-Seq_ESCs_Human1.11589865
60CBP_20019798_ChIP-Seq_JUKART_Human1.10599729
61IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.10599729
62TDRD3_21172665_ChIP-Seq_MCF-7_Human1.10069149
63PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.08878854
64RBPJ_21746931_ChIP-Seq_IB4_Human1.08863135
65MYC_19079543_ChIP-ChIP_MESCs_Mouse1.08791063
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.08630678
67CBX2_27304074_Chip-Seq_ESCs_Mouse1.07193739
68PHF8_20622853_ChIP-Seq_HELA_Human1.06057695
69GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05921775
70TAF2_19829295_ChIP-Seq_ESCs_Human1.05820099
71AR_20517297_ChIP-Seq_VCAP_Human1.04620751
72CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.02365154
73SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.01572188
74GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.99698558
75NANOG_19829295_ChIP-Seq_ESCs_Human0.99443557
76SOX2_19829295_ChIP-Seq_ESCs_Human0.99443557
77NOTCH1_17114293_ChIP-ChIP_T-ALL_Human0.97681954
78HCFC1_20581084_ChIP-Seq_MESCs_Mouse0.96859977
79POU5F1_16153702_ChIP-ChIP_HESCs_Human0.96641985
80NFE2_27457419_Chip-Seq_LIVER_Mouse0.96345267
81CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.96341783
82HOXB7_26014856_ChIP-Seq_BT474_Human0.95579787
83KDM5A_27292631_Chip-Seq_BREAST_Human0.95135215
84EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.94506390
85ER_23166858_ChIP-Seq_MCF-7_Human0.93565170
86ETV1_20927104_ChIP-Seq_GIST48_Human0.93233308
87SOX2_18555785_ChIP-Seq_MESCs_Mouse0.93146932
88FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.91281039
89MYC_19829295_ChIP-Seq_ESCs_Human0.91101294
90P53_21459846_ChIP-Seq_SAOS-2_Human0.90251333
91RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.90033962
92KLF5_20875108_ChIP-Seq_MESCs_Mouse0.89222823
93MYC_19030024_ChIP-ChIP_MESCs_Mouse0.89090166
94EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.89047032
95PADI4_21655091_ChIP-ChIP_MCF-7_Human0.88233405
96TCF4_22108803_ChIP-Seq_LS180_Human0.87005925
97HNFA_21074721_ChIP-Seq_CACO-2_Human0.86332500
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.86033574
99TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.85807816
100NANOG_20526341_ChIP-Seq_ESCs_Human0.85726751

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation5.22504552
2MP0006292_abnormal_olfactory_placode4.48751240
3MP0003787_abnormal_imprinting4.22989187
4MP0005360_urolithiasis3.27385429
5MP0008877_abnormal_DNA_methylation2.89683498
6MP0002837_dystrophic_cardiac_calcinosis2.79024497
7MP0003121_genomic_imprinting2.53405390
8MP0000372_irregular_coat_pigmentation2.51676501
9MP0001348_abnormal_lacrimal_gland2.45484617
10MP0002163_abnormal_gland_morphology2.45023380
11MP0003806_abnormal_nucleotide_metabolis2.33062887
12MP0003123_paternal_imprinting2.20781410
13MP0008875_abnormal_xenobiotic_pharmacok2.20373134
14MP0005379_endocrine/exocrine_gland_phen2.10277576
15MP0002102_abnormal_ear_morphology2.04742790
16MP0008789_abnormal_olfactory_epithelium1.95833970
17MP0008872_abnormal_physiological_respon1.95513394
18MP0005646_abnormal_pituitary_gland1.93766090
19MP0003195_calcinosis1.81645306
20MP0003122_maternal_imprinting1.78971418
21MP0003252_abnormal_bile_duct1.74402289
22MP0002653_abnormal_ependyma_morphology1.64115054
23MP0005377_hearing/vestibular/ear_phenot1.64105956
24MP0003878_abnormal_ear_physiology1.64105956
25MP0005075_abnormal_melanosome_morpholog1.63680233
26MP0002160_abnormal_reproductive_system1.59718941
27MP0005394_taste/olfaction_phenotype1.52041478
28MP0005499_abnormal_olfactory_system1.52041478
29MP0001968_abnormal_touch/_nociception1.49000235
30MP0004142_abnormal_muscle_tone1.44643915
31MP0001984_abnormal_olfaction1.44408923
32MP0002876_abnormal_thyroid_physiology1.40596147
33MP0005084_abnormal_gallbladder_morpholo1.37970883
34MP0003011_delayed_dark_adaptation1.37775671
35MP0005389_reproductive_system_phenotype1.37390574
36MP0001293_anophthalmia1.34702286
37MP0004043_abnormal_pH_regulation1.34613472
38MP0006072_abnormal_retinal_apoptosis1.33254045
39MP0001905_abnormal_dopamine_level1.32071637
40MP0003646_muscle_fatigue1.28859614
41MP0000049_abnormal_middle_ear1.25492528
42MP0002234_abnormal_pharynx_morphology1.24743846
43MP0001835_abnormal_antigen_presentation1.24271169
44MP0003136_yellow_coat_color1.22339287
45MP0002928_abnormal_bile_duct1.21964364
46MP0006276_abnormal_autonomic_nervous1.20726879
47MP0009764_decreased_sensitivity_to1.20062775
48MP0002272_abnormal_nervous_system1.18973269
49MP0002736_abnormal_nociception_after1.18361763
50MP0001986_abnormal_taste_sensitivity1.15059967
51MP0003186_abnormal_redox_activity1.14790764
52MP0004145_abnormal_muscle_electrophysio1.14777863
53MP0005551_abnormal_eye_electrophysiolog1.13540851
54MP0003315_abnormal_perineum_morphology1.13155389
55MP0003718_maternal_effect1.10545982
56MP0005253_abnormal_eye_physiology1.07931103
57MP0006082_CNS_inflammation1.07488986
58MP0001529_abnormal_vocalization1.05546824
59MP0004147_increased_porphyrin_level1.04174608
60MP0001873_stomach_inflammation1.01437656
61MP0009046_muscle_twitch1.00464733
62MP0000685_abnormal_immune_system1.00055992
63MP0001970_abnormal_pain_threshold0.99795747
64MP0002095_abnormal_skin_pigmentation0.98835947
65MP0009745_abnormal_behavioral_response0.94056978
66MP0008058_abnormal_DNA_repair0.92518015
67MP0002733_abnormal_thermal_nociception0.91200305
68MP0005645_abnormal_hypothalamus_physiol0.86079292
69MP0001756_abnormal_urination0.84548289
70MP0005332_abnormal_amino_acid0.83842761
71MP0001919_abnormal_reproductive_system0.83265212
72MP0000631_abnormal_neuroendocrine_gland0.82689028
73MP0004885_abnormal_endolymph0.81918359
74MP0002277_abnormal_respiratory_mucosa0.81844444
75MP0002557_abnormal_social/conspecific_i0.80160495
76MP0004019_abnormal_vitamin_homeostasis0.78985040
77MP0005410_abnormal_fertilization0.78202545
78MP0001501_abnormal_sleep_pattern0.75278952
79MP0002148_abnormal_hypersensitivity_rea0.74543098
80MP0002233_abnormal_nose_morphology0.74162182
81MP0000230_abnormal_systemic_arterial0.73934294
82MP0005195_abnormal_posterior_eye0.72847094
83MP0008775_abnormal_heart_ventricle0.71874970
84MP0001663_abnormal_digestive_system0.71784685
85MP0005671_abnormal_response_to0.70211078
86MP0003638_abnormal_response/metabolism_0.69947514
87MP0002693_abnormal_pancreas_physiology0.68558784
88MP0005386_behavior/neurological_phenoty0.68318537
89MP0004924_abnormal_behavior0.68318537
90MP0000613_abnormal_salivary_gland0.68203313
91MP0002210_abnormal_sex_determination0.68034933
92MP0002138_abnormal_hepatobiliary_system0.67099886
93MP0006036_abnormal_mitochondrial_physio0.65282161
94MP0009333_abnormal_splenocyte_physiolog0.65273691
95MP0001764_abnormal_homeostasis0.64496500
96MP0005636_abnormal_mineral_homeostasis0.63385898
97MP0001790_abnormal_immune_system0.62827897
98MP0005387_immune_system_phenotype0.62827897
99MP0005408_hypopigmentation0.61816100
100MP0002752_abnormal_somatic_nervous0.61757062

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.73615121
2Mitochondrial inheritance (HP:0001427)4.55449464
3Abnormal mitochondria in muscle tissue (HP:0008316)4.23761415
4Increased CSF lactate (HP:0002490)4.14853349
5Acute encephalopathy (HP:0006846)4.05232223
6Increased hepatocellular lipid droplets (HP:0006565)4.03285040
7Progressive macrocephaly (HP:0004481)3.82259553
8Lipid accumulation in hepatocytes (HP:0006561)3.71128546
9Hepatocellular necrosis (HP:0001404)3.61011030
10Hepatic necrosis (HP:0002605)3.50824547
11Abnormality of cells of the erythroid lineage (HP:0012130)3.24320128
12Medial flaring of the eyebrow (HP:0010747)3.22201938
13Molar tooth sign on MRI (HP:0002419)3.18712349
14Abnormality of midbrain morphology (HP:0002418)3.18712349
15Large for gestational age (HP:0001520)3.18575518
16Absent rod-and cone-mediated responses on ERG (HP:0007688)3.18258274
17Renal Fanconi syndrome (HP:0001994)3.18203550
18Cerebral edema (HP:0002181)3.06064448
19Pancreatic fibrosis (HP:0100732)2.98834701
20Optic disc pallor (HP:0000543)2.97576631
213-Methylglutaconic aciduria (HP:0003535)2.93340894
22Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.91581241
23Increased intramyocellular lipid droplets (HP:0012240)2.89305092
24Pancreatic cysts (HP:0001737)2.86963685
25Nephronophthisis (HP:0000090)2.79537842
26Septo-optic dysplasia (HP:0100842)2.70490159
27Sclerocornea (HP:0000647)2.68346817
28Abnormal rod and cone electroretinograms (HP:0008323)2.68094347
29Lactic acidosis (HP:0003128)2.65839202
30Exertional dyspnea (HP:0002875)2.64693583
31Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.63140747
32Elevated erythrocyte sedimentation rate (HP:0003565)2.62387676
33Abnormality of renal resorption (HP:0011038)2.58878944
34Abnormal number of erythroid precursors (HP:0012131)2.56094770
35Congenital, generalized hypertrichosis (HP:0004540)2.53941095
36Macrocytic anemia (HP:0001972)2.53809600
37Increased serum lactate (HP:0002151)2.52941076
38Reticulocytopenia (HP:0001896)2.52787099
39Abnormal respiratory motile cilium physiology (HP:0012261)2.49042060
40True hermaphroditism (HP:0010459)2.45581185
41Limb dystonia (HP:0002451)2.44894852
42Abnormal ciliary motility (HP:0012262)2.42590146
43Gait imbalance (HP:0002141)2.41434801
44Congenital primary aphakia (HP:0007707)2.40030695
45Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.38381250
46Increased muscle lipid content (HP:0009058)2.37134904
47Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.36805390
48Decreased activity of mitochondrial respiratory chain (HP:0008972)2.36805390
49Respiratory difficulties (HP:0002880)2.32377333
50Nephrogenic diabetes insipidus (HP:0009806)2.29958477
51Abnormality of the renal medulla (HP:0100957)2.25800631
52Congenital stationary night blindness (HP:0007642)2.23886602
53Leukodystrophy (HP:0002415)2.22484547
54Respiratory failure (HP:0002878)2.20387156
55Constricted visual fields (HP:0001133)2.20110553
56Dynein arm defect of respiratory motile cilia (HP:0012255)2.19866688
57Absent/shortened dynein arms (HP:0200106)2.19866688
58Abnormality of alanine metabolism (HP:0010916)2.17522906
59Hyperalaninemia (HP:0003348)2.17522906
60Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.17522906
61Exercise intolerance (HP:0003546)2.15526678
62Abnormality of T cell physiology (HP:0011840)2.10811519
63Pendular nystagmus (HP:0012043)2.05608503
64Abnormality of the renal cortex (HP:0011035)2.05359729
65Stenosis of the external auditory canal (HP:0000402)2.04492712
66Pallor (HP:0000980)2.04150048
67Rib fusion (HP:0000902)2.00024778
68Lethargy (HP:0001254)1.99778190
69Colon cancer (HP:0003003)1.97837892
70Absent thumb (HP:0009777)1.97511417
71Decreased electroretinogram (ERG) amplitude (HP:0000654)1.97453335
72Abnormality of urine glucose concentration (HP:0011016)1.96555271
73Glycosuria (HP:0003076)1.96555271
74Hypothermia (HP:0002045)1.95923567
75Aplasia/Hypoplasia of the spleen (HP:0010451)1.94702725
76Chronic hepatic failure (HP:0100626)1.94010682
77Decreased central vision (HP:0007663)1.92992008
78X-linked dominant inheritance (HP:0001423)1.92803918
79Attenuation of retinal blood vessels (HP:0007843)1.91790915
80Asplenia (HP:0001746)1.91445117
81Type I transferrin isoform profile (HP:0003642)1.91412275
82Abnormal hemoglobin (HP:0011902)1.89624856
83Abolished electroretinogram (ERG) (HP:0000550)1.89315269
84Renal cortical cysts (HP:0000803)1.88059318
85Anencephaly (HP:0002323)1.86700574
86Progressive cerebellar ataxia (HP:0002073)1.85331398
87Hyperphosphaturia (HP:0003109)1.84429317
88Absent septum pellucidum (HP:0001331)1.84309620
89Rhinitis (HP:0012384)1.82648260
90Abnormal respiratory epithelium morphology (HP:0012253)1.82524534
91Abnormal respiratory motile cilium morphology (HP:0005938)1.82524534
92Aplasia/Hypoplasia of the sacrum (HP:0008517)1.80116180
93Type II lissencephaly (HP:0007260)1.79808425
94Cystic liver disease (HP:0006706)1.79255902
95Growth hormone deficiency (HP:0000824)1.79210490
96Chronic bronchitis (HP:0004469)1.77912752
97Cleft eyelid (HP:0000625)1.77426920
98Occipital encephalocele (HP:0002085)1.76312295
99Abnormal drinking behavior (HP:0030082)1.75332097
100Polydipsia (HP:0001959)1.75332097

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K24.99328174
2BMPR1B4.21046307
3WNK43.06399853
4CDK192.73183384
5BCKDK2.61184530
6ADRBK22.28688659
7CDK82.22353171
8TNK22.09640484
9GRK12.05205232
10NUAK12.02439344
11TAOK31.88751699
12ZAK1.82060236
13FRK1.71568747
14TGFBR11.67250783
15NEK11.65175035
16VRK21.62495620
17OXSR11.58598132
18NME21.54573185
19STK391.52162728
20LIMK11.50982925
21DYRK21.46428717
22MAP2K61.42372493
23WNK31.34939291
24TXK1.32679387
25PIM21.25074885
26PBK1.22394837
27EPHB21.20554794
28TIE11.19700314
29TAF11.17947046
30MKNK11.17387455
31ABL21.15396167
32TLK11.12144176
33PINK11.11886294
34SRPK11.08744527
35PIK3CA1.06771359
36BCR1.04597186
37CASK1.04441092
38PHKG11.01738993
39PHKG21.01738993
40BMPR20.88715159
41TNIK0.86515096
42ADRBK10.85438519
43PRKCG0.84945967
44MAP3K40.84659755
45PRKCQ0.83466372
46ITK0.81816207
47TEC0.79609475
48RPS6KA50.77968620
49CSF1R0.75650729
50INSRR0.73543707
51NME10.72811445
52IKBKB0.70865515
53PDK20.70263237
54VRK10.69926910
55PRKD30.66563194
56CDK90.65674016
57KIT0.64554755
58DYRK1B0.64333617
59LYN0.64034314
60FLT30.63683970
61PASK0.62945823
62PLK10.62745144
63PLK40.62398396
64MAP2K70.62201398
65DAPK30.60519001
66ACVR1B0.59887753
67MAPKAPK50.59582293
68FES0.58983381
69RPS6KA60.56511801
70BTK0.56001387
71SYK0.55842733
72CHEK20.54577967
73STK38L0.53750456
74CSNK1G20.53591912
75AURKB0.52692826
76STK110.52005588
77PTK60.51254333
78CDK30.50264848
79MAPK150.50190522
80CSNK1G30.50022091
81NTRK20.49674330
82CSNK2A20.49126761
83CSNK2A10.48257043
84PRKACA0.47895656
85MAP4K10.47487696
86CAMK10.46623905
87GRK60.45721454
88EIF2AK30.45383296
89IKBKE0.44978431
90DYRK1A0.44159249
91PLK30.41824746
92MKNK20.40574390
93CAMKK20.40151729
94CSNK1G10.39854587
95RPS6KC10.39420543
96RPS6KL10.39420543
97MARK30.38339583
98DAPK20.37195611
99ATR0.36700497
100EPHA40.36339040

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.25376050
2Oxidative phosphorylation_Homo sapiens_hsa001904.21864345
3Parkinsons disease_Homo sapiens_hsa050123.73222091
4Asthma_Homo sapiens_hsa053103.04186849
5Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.56139432
6Alzheimers disease_Homo sapiens_hsa050102.53158445
7Huntingtons disease_Homo sapiens_hsa050162.51401896
8Protein export_Homo sapiens_hsa030602.45296018
9Allograft rejection_Homo sapiens_hsa053302.24264172
10Intestinal immune network for IgA production_Homo sapiens_hsa046722.18053341
11Cardiac muscle contraction_Homo sapiens_hsa042602.15926283
12Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.15251706
13RNA polymerase_Homo sapiens_hsa030202.12640987
14Autoimmune thyroid disease_Homo sapiens_hsa053202.11067180
15Homologous recombination_Homo sapiens_hsa034402.07067745
16Proteasome_Homo sapiens_hsa030501.86353481
17Linoleic acid metabolism_Homo sapiens_hsa005911.84642511
18RNA degradation_Homo sapiens_hsa030181.82824114
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.67065557
20Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.65929374
21Type I diabetes mellitus_Homo sapiens_hsa049401.58417839
22Nucleotide excision repair_Homo sapiens_hsa034201.49585788
23Graft-versus-host disease_Homo sapiens_hsa053321.41074924
24Basal transcription factors_Homo sapiens_hsa030221.37316923
25Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.31663783
26Pyrimidine metabolism_Homo sapiens_hsa002401.31418722
27Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.29424225
28Base excision repair_Homo sapiens_hsa034101.23473512
29Caffeine metabolism_Homo sapiens_hsa002321.21223553
30Tryptophan metabolism_Homo sapiens_hsa003801.19102248
31Nitrogen metabolism_Homo sapiens_hsa009101.17645393
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.16189911
33Mismatch repair_Homo sapiens_hsa034301.14924377
34DNA replication_Homo sapiens_hsa030301.10776639
35Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.08033022
36Butanoate metabolism_Homo sapiens_hsa006501.05241536
37Fanconi anemia pathway_Homo sapiens_hsa034601.02101032
38Maturity onset diabetes of the young_Homo sapiens_hsa049501.00262994
39Purine metabolism_Homo sapiens_hsa002300.98969746
40Propanoate metabolism_Homo sapiens_hsa006400.98731896
41Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.95011877
42Arachidonic acid metabolism_Homo sapiens_hsa005900.93251772
43Spliceosome_Homo sapiens_hsa030400.93175454
44Olfactory transduction_Homo sapiens_hsa047400.87886171
45Retinol metabolism_Homo sapiens_hsa008300.87740973
46Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.84253455
47Phototransduction_Homo sapiens_hsa047440.84034511
48Ether lipid metabolism_Homo sapiens_hsa005650.82218246
49Peroxisome_Homo sapiens_hsa041460.80462774
50Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79464481
51Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77593335
52Vitamin B6 metabolism_Homo sapiens_hsa007500.74522531
53RNA transport_Homo sapiens_hsa030130.73194461
54Chemical carcinogenesis_Homo sapiens_hsa052040.71880689
55Metabolic pathways_Homo sapiens_hsa011000.71756301
56Rheumatoid arthritis_Homo sapiens_hsa053230.71604999
57Fatty acid elongation_Homo sapiens_hsa000620.68827453
58Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.68790619
59Steroid hormone biosynthesis_Homo sapiens_hsa001400.65288209
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.63132778
61SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62259350
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.61286158
63Viral myocarditis_Homo sapiens_hsa054160.61285687
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59573207
65Fat digestion and absorption_Homo sapiens_hsa049750.59186450
66Ovarian steroidogenesis_Homo sapiens_hsa049130.58487768
67Nicotine addiction_Homo sapiens_hsa050330.55290794
68Hematopoietic cell lineage_Homo sapiens_hsa046400.53806787
69Cysteine and methionine metabolism_Homo sapiens_hsa002700.52416354
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.52198494
71Primary immunodeficiency_Homo sapiens_hsa053400.52121625
72Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50627553
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.50444529
74Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.50224069
75Morphine addiction_Homo sapiens_hsa050320.50016161
76p53 signaling pathway_Homo sapiens_hsa041150.48196201
77Salivary secretion_Homo sapiens_hsa049700.47688974
78Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45612192
79Selenocompound metabolism_Homo sapiens_hsa004500.44575344
80Taste transduction_Homo sapiens_hsa047420.44200965
81Insulin secretion_Homo sapiens_hsa049110.43612044
82Staphylococcus aureus infection_Homo sapiens_hsa051500.41672524
83beta-Alanine metabolism_Homo sapiens_hsa004100.41061974
84Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.40853524
85Primary bile acid biosynthesis_Homo sapiens_hsa001200.40810771
86One carbon pool by folate_Homo sapiens_hsa006700.36505147
87Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.34109599
88Antigen processing and presentation_Homo sapiens_hsa046120.33483620
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31656413
90Fatty acid degradation_Homo sapiens_hsa000710.29702803
91African trypanosomiasis_Homo sapiens_hsa051430.29597606
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.29560029
93Systemic lupus erythematosus_Homo sapiens_hsa053220.26640800
94Pentose and glucuronate interconversions_Homo sapiens_hsa000400.24715957
95Glycerolipid metabolism_Homo sapiens_hsa005610.24696631
96Mineral absorption_Homo sapiens_hsa049780.23633436
97GABAergic synapse_Homo sapiens_hsa047270.22776551
98Steroid biosynthesis_Homo sapiens_hsa001000.20235456
99Serotonergic synapse_Homo sapiens_hsa047260.20161998
100Fatty acid metabolism_Homo sapiens_hsa012120.16368697

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »