

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 7.24701037 |
| 2 | nonmotile primary cilium assembly (GO:0035058) | 5.89923880 |
| 3 | ribosomal small subunit biogenesis (GO:0042274) | 5.48355086 |
| 4 | viral transcription (GO:0019083) | 5.44744632 |
| 5 | translational termination (GO:0006415) | 5.25016160 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 4.66395616 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.64825825 |
| 8 | protein neddylation (GO:0045116) | 4.59839182 |
| 9 | protein targeting to ER (GO:0045047) | 4.58243218 |
| 10 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 4.55269604 |
| 11 | substrate-independent telencephalic tangential migration (GO:0021826) | 4.55269604 |
| 12 | negative regulation of mast cell activation (GO:0033004) | 4.40628307 |
| 13 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.40408718 |
| 14 | behavioral response to nicotine (GO:0035095) | 4.38501459 |
| 15 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.36677752 |
| 16 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.36677752 |
| 17 | NADH dehydrogenase complex assembly (GO:0010257) | 4.36677752 |
| 18 | protein localization to endoplasmic reticulum (GO:0070972) | 4.30561169 |
| 19 | cellular potassium ion homeostasis (GO:0030007) | 4.30050496 |
| 20 | translational elongation (GO:0006414) | 4.15669953 |
| 21 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 4.12461581 |
| 22 | protein complex biogenesis (GO:0070271) | 4.10269063 |
| 23 | potassium ion homeostasis (GO:0055075) | 4.00152518 |
| 24 | regulation of cilium movement (GO:0003352) | 3.91419529 |
| 25 | body morphogenesis (GO:0010171) | 3.89647619 |
| 26 | cellular protein complex disassembly (GO:0043624) | 3.88419294 |
| 27 | positive regulation of growth hormone secretion (GO:0060124) | 3.87847619 |
| 28 | nucleobase catabolic process (GO:0046113) | 3.76660363 |
| 29 | viral life cycle (GO:0019058) | 3.75363655 |
| 30 | negative regulation of response to food (GO:0032096) | 3.75232396 |
| 31 | negative regulation of appetite (GO:0032099) | 3.75232396 |
| 32 | ribosomal small subunit assembly (GO:0000028) | 3.74188043 |
| 33 | embryonic body morphogenesis (GO:0010172) | 3.72885263 |
| 34 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.68453186 |
| 35 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.67133476 |
| 36 | somite development (GO:0061053) | 3.65101197 |
| 37 | myeloid cell homeostasis (GO:0002262) | 3.64819584 |
| 38 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.57560676 |
| 39 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.55853844 |
| 40 | ATP synthesis coupled proton transport (GO:0015986) | 3.55853844 |
| 41 | nephron epithelium morphogenesis (GO:0072088) | 3.54838933 |
| 42 | nephron tubule morphogenesis (GO:0072078) | 3.54838933 |
| 43 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.48236059 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.37458356 |
| 45 | cell wall macromolecule catabolic process (GO:0016998) | 3.37239103 |
| 46 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.36979277 |
| 47 | microtubule severing (GO:0051013) | 3.34446970 |
| 48 | centriole replication (GO:0007099) | 3.27555582 |
| 49 | protein localization to cilium (GO:0061512) | 3.24319816 |
| 50 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.23681348 |
| 51 | renal tubule morphogenesis (GO:0061333) | 3.22897232 |
| 52 | protein complex disassembly (GO:0043241) | 3.21317548 |
| 53 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 3.19556347 |
| 54 | sodium ion export (GO:0071436) | 3.18569187 |
| 55 | ribosomal large subunit biogenesis (GO:0042273) | 3.18454788 |
| 56 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 3.18367432 |
| 57 | chaperone-mediated protein transport (GO:0072321) | 3.14816843 |
| 58 | protein targeting to membrane (GO:0006612) | 3.11214938 |
| 59 | macromolecular complex disassembly (GO:0032984) | 3.10002930 |
| 60 | pattern specification involved in kidney development (GO:0061004) | 3.07295682 |
| 61 | Sertoli cell development (GO:0060009) | 3.06100487 |
| 62 | cell proliferation in forebrain (GO:0021846) | 3.05799845 |
| 63 | segment specification (GO:0007379) | 2.99554143 |
| 64 | pyrimidine nucleobase catabolic process (GO:0006208) | 2.97344061 |
| 65 | regulation of microtubule-based movement (GO:0060632) | 2.94894445 |
| 66 | membrane repolarization (GO:0086009) | 2.92468270 |
| 67 | dentate gyrus development (GO:0021542) | 2.91714941 |
| 68 | translational initiation (GO:0006413) | 2.90430820 |
| 69 | behavioral response to ethanol (GO:0048149) | 2.89626413 |
| 70 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.88646730 |
| 71 | regulation of cellular respiration (GO:0043457) | 2.88024749 |
| 72 | electron transport chain (GO:0022900) | 2.85793464 |
| 73 | neuron fate determination (GO:0048664) | 2.85475222 |
| 74 | respiratory electron transport chain (GO:0022904) | 2.83584645 |
| 75 | cAMP-mediated signaling (GO:0019933) | 2.81984147 |
| 76 | cell wall macromolecule metabolic process (GO:0044036) | 2.81422644 |
| 77 | spinal cord association neuron differentiation (GO:0021527) | 2.79299771 |
| 78 | glycerophospholipid catabolic process (GO:0046475) | 2.79253041 |
| 79 | platelet dense granule organization (GO:0060155) | 2.76064102 |
| 80 | striatum development (GO:0021756) | 2.74701024 |
| 81 | potassium ion import (GO:0010107) | 2.74367460 |
| 82 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.71129976 |
| 83 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.71068506 |
| 84 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.70397398 |
| 85 | regulation of growth hormone secretion (GO:0060123) | 2.67760742 |
| 86 | brain morphogenesis (GO:0048854) | 2.67055598 |
| 87 | atrial cardiac muscle cell action potential (GO:0086014) | 2.65965768 |
| 88 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.63410806 |
| 89 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.63252290 |
| 90 | regulation of response to food (GO:0032095) | 2.61588689 |
| 91 | cellular sodium ion homeostasis (GO:0006883) | 2.61343391 |
| 92 | cellular response to leptin stimulus (GO:0044320) | 2.56967051 |
| 93 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.56821064 |
| 94 | DNA deamination (GO:0045006) | 2.56476508 |
| 95 | sodium-independent organic anion transport (GO:0043252) | 2.54617239 |
| 96 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.50607843 |
| 97 | mRNA catabolic process (GO:0006402) | 2.50526620 |
| 98 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.50038876 |
| 99 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.50038876 |
| 100 | parturition (GO:0007567) | 2.49161054 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.86196701 |
| 2 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 3.24565601 |
| 3 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 2.67714717 |
| 4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.54259181 |
| 5 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.49312676 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.39630561 |
| 7 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.31901476 |
| 8 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.24680876 |
| 9 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.19252650 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11190481 |
| 11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.99456634 |
| 12 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.96712799 |
| 13 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.95410021 |
| 14 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.92071335 |
| 15 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.85520921 |
| 16 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.79344483 |
| 17 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.79344483 |
| 18 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.79207445 |
| 19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.79037260 |
| 20 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.73127200 |
| 21 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.70766068 |
| 22 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.68989616 |
| 23 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.68386891 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.68176575 |
| 25 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.67281801 |
| 26 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.58889052 |
| 27 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.58889052 |
| 28 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.58134199 |
| 29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.55314392 |
| 30 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.51043085 |
| 31 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.50855818 |
| 32 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.49703363 |
| 33 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.49344430 |
| 34 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.49012390 |
| 35 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.47280989 |
| 36 | EWS_26573619_Chip-Seq_HEK293_Human | 1.46526275 |
| 37 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.45812807 |
| 38 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.45728600 |
| 39 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.44271934 |
| 40 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.43411699 |
| 41 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.42203138 |
| 42 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40040354 |
| 43 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.38287292 |
| 44 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.35626935 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34011276 |
| 46 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.28552883 |
| 47 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.27221605 |
| 48 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.26638818 |
| 49 | FUS_26573619_Chip-Seq_HEK293_Human | 1.23728474 |
| 50 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.23138669 |
| 51 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.19497283 |
| 52 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.18796561 |
| 53 | AR_25329375_ChIP-Seq_VCAP_Human | 1.18423246 |
| 54 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.18318802 |
| 55 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.18269689 |
| 56 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18227448 |
| 57 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.18088692 |
| 58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.18016346 |
| 59 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17892438 |
| 60 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.17855438 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.17440827 |
| 62 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.17309566 |
| 63 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.16821638 |
| 64 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16438709 |
| 65 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15636800 |
| 66 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15636800 |
| 67 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.14666089 |
| 68 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.13602867 |
| 69 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12828410 |
| 70 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.12528828 |
| 71 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.11131309 |
| 72 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.10479994 |
| 73 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.10393939 |
| 74 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10321274 |
| 75 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.10152059 |
| 76 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.09916762 |
| 77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09842220 |
| 78 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.05951233 |
| 79 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05483818 |
| 80 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.05026517 |
| 81 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.05026517 |
| 82 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.04861114 |
| 83 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.03906886 |
| 84 | AR_20517297_ChIP-Seq_VCAP_Human | 1.02744077 |
| 85 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.02536242 |
| 86 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.00833670 |
| 87 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.99716422 |
| 88 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98720343 |
| 89 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.98715469 |
| 90 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.98705663 |
| 91 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.98208580 |
| 92 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.97395372 |
| 93 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.96549182 |
| 94 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.96140139 |
| 95 | STAT3_19079543_ChIP-ChIP_MESCs_Mouse | 0.95378478 |
| 96 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.95262605 |
| 97 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.94237410 |
| 98 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.93129739 |
| 99 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.92745071 |
| 100 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.92717498 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003787_abnormal_imprinting | 3.88440361 |
| 2 | MP0004142_abnormal_muscle_tone | 3.29266594 |
| 3 | MP0002138_abnormal_hepatobiliary_system | 3.25560288 |
| 4 | MP0005423_abnormal_somatic_nervous | 3.07045034 |
| 5 | MP0002163_abnormal_gland_morphology | 3.04521228 |
| 6 | MP0005084_abnormal_gallbladder_morpholo | 3.00229334 |
| 7 | MP0001529_abnormal_vocalization | 2.97487176 |
| 8 | MP0009379_abnormal_foot_pigmentation | 2.87374072 |
| 9 | MP0003122_maternal_imprinting | 2.70543251 |
| 10 | MP0005645_abnormal_hypothalamus_physiol | 2.51588542 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.47274291 |
| 12 | MP0003123_paternal_imprinting | 2.38428010 |
| 13 | MP0003183_abnormal_peptide_metabolism | 2.31493439 |
| 14 | MP0008789_abnormal_olfactory_epithelium | 2.30747257 |
| 15 | MP0001968_abnormal_touch/_nociception | 2.27430189 |
| 16 | MP0002837_dystrophic_cardiac_calcinosis | 2.27251545 |
| 17 | MP0003646_muscle_fatigue | 2.14987780 |
| 18 | MP0001984_abnormal_olfaction | 2.08399336 |
| 19 | MP0002139_abnormal_hepatobiliary_system | 2.03886686 |
| 20 | MP0005379_endocrine/exocrine_gland_phen | 1.90757666 |
| 21 | MP0000013_abnormal_adipose_tissue | 1.89984180 |
| 22 | MP0002653_abnormal_ependyma_morphology | 1.85910669 |
| 23 | MP0003121_genomic_imprinting | 1.82480818 |
| 24 | MP0005394_taste/olfaction_phenotype | 1.77944176 |
| 25 | MP0005499_abnormal_olfactory_system | 1.77944176 |
| 26 | MP0002734_abnormal_mechanical_nocicepti | 1.70847729 |
| 27 | MP0001485_abnormal_pinna_reflex | 1.63981898 |
| 28 | MP0001188_hyperpigmentation | 1.62510953 |
| 29 | MP0000778_abnormal_nervous_system | 1.58263943 |
| 30 | MP0009046_muscle_twitch | 1.54519813 |
| 31 | MP0004885_abnormal_endolymph | 1.53696216 |
| 32 | MP0008877_abnormal_DNA_methylation | 1.50587147 |
| 33 | MP0001970_abnormal_pain_threshold | 1.49553262 |
| 34 | MP0002272_abnormal_nervous_system | 1.48983011 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.45852267 |
| 36 | MP0001486_abnormal_startle_reflex | 1.44628686 |
| 37 | MP0002102_abnormal_ear_morphology | 1.43750386 |
| 38 | MP0004742_abnormal_vestibular_system | 1.42709181 |
| 39 | MP0001440_abnormal_grooming_behavior | 1.41765213 |
| 40 | MP0002234_abnormal_pharynx_morphology | 1.39733431 |
| 41 | MP0005551_abnormal_eye_electrophysiolog | 1.37222069 |
| 42 | MP0002572_abnormal_emotion/affect_behav | 1.35543644 |
| 43 | MP0009745_abnormal_behavioral_response | 1.33915676 |
| 44 | MP0002909_abnormal_adrenal_gland | 1.31830862 |
| 45 | MP0003879_abnormal_hair_cell | 1.30121485 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.30006318 |
| 47 | MP0003195_calcinosis | 1.26501310 |
| 48 | MP0001905_abnormal_dopamine_level | 1.24445672 |
| 49 | MP0003635_abnormal_synaptic_transmissio | 1.23925664 |
| 50 | MP0002928_abnormal_bile_duct | 1.23699287 |
| 51 | MP0002733_abnormal_thermal_nociception | 1.23548844 |
| 52 | MP0002067_abnormal_sensory_capabilities | 1.22321399 |
| 53 | MP0002064_seizures | 1.22123372 |
| 54 | MP0002063_abnormal_learning/memory/cond | 1.19570065 |
| 55 | MP0002557_abnormal_social/conspecific_i | 1.19028704 |
| 56 | MP0005389_reproductive_system_phenotype | 1.14769615 |
| 57 | MP0003385_abnormal_body_wall | 1.14374864 |
| 58 | MP0005670_abnormal_white_adipose | 1.09775214 |
| 59 | MP0003186_abnormal_redox_activity | 1.08627247 |
| 60 | MP0000516_abnormal_urinary_system | 1.08340921 |
| 61 | MP0005367_renal/urinary_system_phenotyp | 1.08340921 |
| 62 | MP0006276_abnormal_autonomic_nervous | 1.07815557 |
| 63 | MP0000631_abnormal_neuroendocrine_gland | 1.05043377 |
| 64 | MP0009780_abnormal_chondrocyte_physiolo | 1.04358865 |
| 65 | MP0002736_abnormal_nociception_after | 1.03695041 |
| 66 | MP0003880_abnormal_central_pattern | 1.03334976 |
| 67 | MP0002160_abnormal_reproductive_system | 1.02580273 |
| 68 | MP0000955_abnormal_spinal_cord | 1.01836171 |
| 69 | MP0005248_abnormal_Harderian_gland | 1.01226534 |
| 70 | MP0003136_yellow_coat_color | 0.99577133 |
| 71 | MP0004924_abnormal_behavior | 0.95633884 |
| 72 | MP0005386_behavior/neurological_phenoty | 0.95633884 |
| 73 | MP0005195_abnormal_posterior_eye | 0.92756024 |
| 74 | MP0002752_abnormal_somatic_nervous | 0.91583525 |
| 75 | MP0004147_increased_porphyrin_level | 0.90276391 |
| 76 | MP0002882_abnormal_neuron_morphology | 0.84900146 |
| 77 | MP0002735_abnormal_chemical_nociception | 0.83854105 |
| 78 | MP0000026_abnormal_inner_ear | 0.83564648 |
| 79 | MP0004145_abnormal_muscle_electrophysio | 0.82703375 |
| 80 | MP0002233_abnormal_nose_morphology | 0.81588185 |
| 81 | MP0002184_abnormal_innervation | 0.78888174 |
| 82 | MP0005253_abnormal_eye_physiology | 0.78105845 |
| 83 | MP0004043_abnormal_pH_regulation | 0.77731431 |
| 84 | MP0003567_abnormal_fetal_cardiomyocyte | 0.75706889 |
| 85 | MP0003938_abnormal_ear_development | 0.74551734 |
| 86 | MP0002152_abnormal_brain_morphology | 0.72403021 |
| 87 | MP0003718_maternal_effect | 0.72112831 |
| 88 | MP0002876_abnormal_thyroid_physiology | 0.71981287 |
| 89 | MP0000230_abnormal_systemic_arterial | 0.71904166 |
| 90 | MP0010030_abnormal_orbit_morphology | 0.71614339 |
| 91 | MP0001286_abnormal_eye_development | 0.71578069 |
| 92 | MP0004859_abnormal_synaptic_plasticity | 0.71189904 |
| 93 | MP0000049_abnormal_middle_ear | 0.70968197 |
| 94 | MP0008872_abnormal_physiological_respon | 0.70035329 |
| 95 | MP0001270_distended_abdomen | 0.69505559 |
| 96 | MP0002090_abnormal_vision | 0.68383957 |
| 97 | MP0001963_abnormal_hearing_physiology | 0.68223177 |
| 98 | MP0001324_abnormal_eye_pigmentation | 0.67380191 |
| 99 | MP0005171_absent_coat_pigmentation | 0.67239372 |
| 100 | MP0000534_abnormal_ureter_morphology | 0.67072189 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 7.02843439 |
| 2 | Abnormal pancreas size (HP:0012094) | 4.56541320 |
| 3 | Methylmalonic acidemia (HP:0002912) | 4.43006426 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 3.94559991 |
| 5 | Abnormality of midbrain morphology (HP:0002418) | 3.88402101 |
| 6 | Molar tooth sign on MRI (HP:0002419) | 3.88402101 |
| 7 | Septo-optic dysplasia (HP:0100842) | 3.76140237 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.65454252 |
| 9 | Methylmalonic aciduria (HP:0012120) | 3.55042343 |
| 10 | Hypoplasia of the uterus (HP:0000013) | 3.51483711 |
| 11 | Agitation (HP:0000713) | 3.47802830 |
| 12 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.43288558 |
| 13 | Medial flaring of the eyebrow (HP:0010747) | 3.37515779 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.30213599 |
| 15 | Mitochondrial inheritance (HP:0001427) | 3.27635562 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.20504246 |
| 17 | Gait imbalance (HP:0002141) | 3.19212847 |
| 18 | Acute encephalopathy (HP:0006846) | 3.17705596 |
| 19 | Abnormal hemoglobin (HP:0011902) | 3.13106048 |
| 20 | Stenosis of the external auditory canal (HP:0000402) | 3.12596095 |
| 21 | Nephrogenic diabetes insipidus (HP:0009806) | 3.04851768 |
| 22 | Hepatic necrosis (HP:0002605) | 3.03298622 |
| 23 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.00312535 |
| 24 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.98803467 |
| 25 | Congenital primary aphakia (HP:0007707) | 2.92082941 |
| 26 | Macrocytic anemia (HP:0001972) | 2.89235135 |
| 27 | Abnormality of vitamin B metabolism (HP:0004340) | 2.82656180 |
| 28 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.79667200 |
| 29 | Exertional dyspnea (HP:0002875) | 2.78461060 |
| 30 | Myokymia (HP:0002411) | 2.75496570 |
| 31 | Hemiparesis (HP:0001269) | 2.64794050 |
| 32 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.64392821 |
| 33 | Absent thumb (HP:0009777) | 2.60935517 |
| 34 | Increased CSF lactate (HP:0002490) | 2.58246593 |
| 35 | Increased hepatocellular lipid droplets (HP:0006565) | 2.57789763 |
| 36 | Type II lissencephaly (HP:0007260) | 2.57485618 |
| 37 | Hyperventilation (HP:0002883) | 2.52372891 |
| 38 | Pallor (HP:0000980) | 2.47557647 |
| 39 | Vaginal atresia (HP:0000148) | 2.47129223 |
| 40 | Genital tract atresia (HP:0001827) | 2.47102640 |
| 41 | Focal seizures (HP:0007359) | 2.46383220 |
| 42 | Abnormality of the labia minora (HP:0012880) | 2.45730007 |
| 43 | Focal motor seizures (HP:0011153) | 2.42856171 |
| 44 | Abolished electroretinogram (ERG) (HP:0000550) | 2.39908554 |
| 45 | Confusion (HP:0001289) | 2.36461765 |
| 46 | Leukodystrophy (HP:0002415) | 2.34461622 |
| 47 | Adrenal hypoplasia (HP:0000835) | 2.34300497 |
| 48 | Pendular nystagmus (HP:0012043) | 2.33658234 |
| 49 | Hyperglycinemia (HP:0002154) | 2.33320562 |
| 50 | Neoplasm of the adrenal cortex (HP:0100641) | 2.30372981 |
| 51 | Lipid accumulation in hepatocytes (HP:0006561) | 2.29018780 |
| 52 | Optic nerve hypoplasia (HP:0000609) | 2.28252647 |
| 53 | 3-Methylglutaconic aciduria (HP:0003535) | 2.24265363 |
| 54 | Hepatoblastoma (HP:0002884) | 2.23202760 |
| 55 | Pancreatic cysts (HP:0001737) | 2.22171627 |
| 56 | Cerebral edema (HP:0002181) | 2.21847336 |
| 57 | Dialeptic seizures (HP:0011146) | 2.20525426 |
| 58 | Poor coordination (HP:0002370) | 2.14514150 |
| 59 | Intestinal atresia (HP:0011100) | 2.08921800 |
| 60 | Cerebral palsy (HP:0100021) | 2.06189498 |
| 61 | Absent septum pellucidum (HP:0001331) | 2.05853845 |
| 62 | Abnormality of vitamin metabolism (HP:0100508) | 2.05388661 |
| 63 | Polyphagia (HP:0002591) | 2.01063516 |
| 64 | Neoplasm of the oral cavity (HP:0100649) | 2.01056539 |
| 65 | Abnormality of urine glucose concentration (HP:0011016) | 1.98680877 |
| 66 | Glycosuria (HP:0003076) | 1.98680877 |
| 67 | Rectovaginal fistula (HP:0000143) | 1.97378514 |
| 68 | Rectal fistula (HP:0100590) | 1.97378514 |
| 69 | Pancreatic fibrosis (HP:0100732) | 1.96947792 |
| 70 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.96927018 |
| 71 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.96888789 |
| 72 | Vitreoretinal degeneration (HP:0000655) | 1.93481868 |
| 73 | Bifid tongue (HP:0010297) | 1.93323225 |
| 74 | Nephronophthisis (HP:0000090) | 1.91461326 |
| 75 | Abnormality of lateral ventricle (HP:0030047) | 1.90731720 |
| 76 | Horseshoe kidney (HP:0000085) | 1.89192905 |
| 77 | Restlessness (HP:0000711) | 1.89180539 |
| 78 | Status epilepticus (HP:0002133) | 1.88776219 |
| 79 | Abnormality of homocysteine metabolism (HP:0010919) | 1.86418878 |
| 80 | Homocystinuria (HP:0002156) | 1.86418878 |
| 81 | Inability to walk (HP:0002540) | 1.85712820 |
| 82 | Increased intramyocellular lipid droplets (HP:0012240) | 1.85552425 |
| 83 | Increased serum lactate (HP:0002151) | 1.85357323 |
| 84 | Renal Fanconi syndrome (HP:0001994) | 1.83813083 |
| 85 | Anencephaly (HP:0002323) | 1.82268558 |
| 86 | Broad-based gait (HP:0002136) | 1.81342561 |
| 87 | Global brain atrophy (HP:0002283) | 1.81314641 |
| 88 | True hermaphroditism (HP:0010459) | 1.79548530 |
| 89 | Congenital stationary night blindness (HP:0007642) | 1.79130611 |
| 90 | Lissencephaly (HP:0001339) | 1.78092480 |
| 91 | Cystic liver disease (HP:0006706) | 1.77838132 |
| 92 | Growth hormone deficiency (HP:0000824) | 1.75118124 |
| 93 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.75100004 |
| 94 | Cerebellar dysplasia (HP:0007033) | 1.73698785 |
| 95 | Shawl scrotum (HP:0000049) | 1.72755230 |
| 96 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.72460106 |
| 97 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 1.72460106 |
| 98 | Abnormal hair whorl (HP:0010721) | 1.71777025 |
| 99 | Abnormality of reticulocytes (HP:0004312) | 1.69872048 |
| 100 | Abnormal number of erythroid precursors (HP:0012131) | 1.67897170 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CASK | 4.62088963 |
| 2 | MAP3K4 | 3.77562919 |
| 3 | WNK4 | 2.99918175 |
| 4 | WNK3 | 2.58892265 |
| 5 | TNIK | 2.52428851 |
| 6 | CCNB1 | 2.42804423 |
| 7 | ADRBK2 | 2.29084056 |
| 8 | MARK1 | 2.16006340 |
| 9 | TRIM28 | 2.03906162 |
| 10 | DYRK2 | 1.95585994 |
| 11 | GRK1 | 1.87855674 |
| 12 | MAPK13 | 1.84894780 |
| 13 | KSR1 | 1.76601366 |
| 14 | STK16 | 1.75726199 |
| 15 | MARK3 | 1.66595098 |
| 16 | PINK1 | 1.66259837 |
| 17 | MAP3K13 | 1.65024974 |
| 18 | NUAK1 | 1.62060475 |
| 19 | EPHB2 | 1.54531184 |
| 20 | PLK2 | 1.52222143 |
| 21 | TYRO3 | 1.48294463 |
| 22 | PRKCI | 1.46007147 |
| 23 | BMPR1B | 1.45643301 |
| 24 | NTRK2 | 1.42141494 |
| 25 | FRK | 1.42004906 |
| 26 | CAMKK2 | 1.40243614 |
| 27 | PIK3CA | 1.39113467 |
| 28 | EPHA4 | 1.38356361 |
| 29 | LRRK2 | 1.34693865 |
| 30 | MINK1 | 1.33174134 |
| 31 | CDK19 | 1.32869943 |
| 32 | CSNK1G1 | 1.27476700 |
| 33 | ZAK | 1.26116758 |
| 34 | CSNK1G3 | 1.25961780 |
| 35 | PRKCG | 1.25864400 |
| 36 | CSNK1G2 | 1.22934681 |
| 37 | PLK4 | 1.19839742 |
| 38 | NTRK3 | 1.13006307 |
| 39 | MAP4K2 | 1.07978751 |
| 40 | CDC7 | 1.06437006 |
| 41 | PKN1 | 1.04760719 |
| 42 | MAP3K6 | 1.00599913 |
| 43 | CSNK1A1L | 0.99689512 |
| 44 | PRKCQ | 0.96999728 |
| 45 | ADRBK1 | 0.95279435 |
| 46 | MAP2K7 | 0.93374909 |
| 47 | MAP2K6 | 0.91737498 |
| 48 | PRKCZ | 0.90202961 |
| 49 | STK11 | 0.88783859 |
| 50 | ICK | 0.83333929 |
| 51 | ZAP70 | 0.82273492 |
| 52 | PRKCE | 0.81699134 |
| 53 | CAMK2A | 0.80556360 |
| 54 | SGK1 | 0.79349057 |
| 55 | NLK | 0.77107818 |
| 56 | EPHA3 | 0.74904471 |
| 57 | TIE1 | 0.74391646 |
| 58 | INSRR | 0.73744636 |
| 59 | PRKACA | 0.69592619 |
| 60 | WNK1 | 0.66919373 |
| 61 | PHKG1 | 0.66854891 |
| 62 | PHKG2 | 0.66854891 |
| 63 | STK39 | 0.66553136 |
| 64 | EIF2AK1 | 0.65956803 |
| 65 | CAMK1 | 0.65657928 |
| 66 | TLK1 | 0.65104720 |
| 67 | ILK | 0.64650899 |
| 68 | CAMKK1 | 0.61335755 |
| 69 | CSNK2A2 | 0.61200623 |
| 70 | PNCK | 0.60775297 |
| 71 | MKNK2 | 0.59520357 |
| 72 | DAPK3 | 0.57915329 |
| 73 | BCKDK | 0.57860015 |
| 74 | CAMK4 | 0.55453943 |
| 75 | PDK2 | 0.54749125 |
| 76 | CAMK1D | 0.54153174 |
| 77 | PAK3 | 0.52860239 |
| 78 | DMPK | 0.52632694 |
| 79 | CSNK1E | 0.52380065 |
| 80 | DAPK2 | 0.52341565 |
| 81 | OXSR1 | 0.50107275 |
| 82 | MAP2K4 | 0.47217070 |
| 83 | PAK6 | 0.46750983 |
| 84 | PIM2 | 0.46327779 |
| 85 | CSNK1A1 | 0.46198865 |
| 86 | PIM1 | 0.44827264 |
| 87 | PRKCA | 0.44718223 |
| 88 | PLK1 | 0.43861624 |
| 89 | PRKDC | 0.43345763 |
| 90 | CAMK1G | 0.41696776 |
| 91 | OBSCN | 0.41609765 |
| 92 | MST4 | 0.40304504 |
| 93 | ROCK1 | 0.39600768 |
| 94 | MAP3K11 | 0.38605579 |
| 95 | MAPK7 | 0.37764647 |
| 96 | PRKG1 | 0.36291094 |
| 97 | DYRK1B | 0.35834845 |
| 98 | MAPKAPK5 | 0.34297572 |
| 99 | MAPK12 | 0.34280168 |
| 100 | ERBB2 | 0.34083709 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.29807126 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.88301259 |
| 3 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.18389324 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.95992733 |
| 5 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.81552797 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.78212258 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40660943 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.33888968 |
| 9 | Nicotine addiction_Homo sapiens_hsa05033 | 2.30596445 |
| 10 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 2.23863637 |
| 11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.22616117 |
| 12 | Asthma_Homo sapiens_hsa05310 | 1.94085979 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.91185845 |
| 14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79423472 |
| 15 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.76503668 |
| 16 | Taste transduction_Homo sapiens_hsa04742 | 1.59608518 |
| 17 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.50883011 |
| 18 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.37894272 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.37490030 |
| 20 | RNA polymerase_Homo sapiens_hsa03020 | 1.37314113 |
| 21 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.34816068 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.33244520 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.31267120 |
| 24 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.27208398 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.22385772 |
| 26 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.21655322 |
| 27 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.19855816 |
| 28 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.18604368 |
| 29 | Insulin secretion_Homo sapiens_hsa04911 | 1.17608781 |
| 30 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.14615394 |
| 31 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.10372409 |
| 32 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.07353657 |
| 33 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.06393973 |
| 34 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.03223996 |
| 35 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.02688494 |
| 36 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.01199258 |
| 37 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.00714143 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.00481130 |
| 39 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.98937899 |
| 40 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.98891297 |
| 41 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.98587066 |
| 42 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.97874553 |
| 43 | Allograft rejection_Homo sapiens_hsa05330 | 0.96540701 |
| 44 | GABAergic synapse_Homo sapiens_hsa04727 | 0.95626065 |
| 45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.94371756 |
| 46 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93142562 |
| 47 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.89530136 |
| 48 | Salivary secretion_Homo sapiens_hsa04970 | 0.88743399 |
| 49 | Morphine addiction_Homo sapiens_hsa05032 | 0.88385452 |
| 50 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.84528523 |
| 51 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.83788614 |
| 52 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.83624629 |
| 53 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.82883685 |
| 54 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.80355761 |
| 55 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.77772614 |
| 56 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.77027640 |
| 57 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.76240383 |
| 58 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.75466198 |
| 59 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.74983304 |
| 60 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.74537145 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.72703885 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.72033971 |
| 63 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.71752371 |
| 64 | Proteasome_Homo sapiens_hsa03050 | 0.70467019 |
| 65 | Olfactory transduction_Homo sapiens_hsa04740 | 0.70160192 |
| 66 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.70146954 |
| 67 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.69968122 |
| 68 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.68984353 |
| 69 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68711422 |
| 70 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.67127129 |
| 71 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.66933035 |
| 72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66630110 |
| 73 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.65786705 |
| 74 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.65748120 |
| 75 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.65096617 |
| 76 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.64271146 |
| 77 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.64100031 |
| 78 | Circadian entrainment_Homo sapiens_hsa04713 | 0.63816078 |
| 79 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.63586598 |
| 80 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.62600821 |
| 81 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.61770218 |
| 82 | Homologous recombination_Homo sapiens_hsa03440 | 0.61594337 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.59412520 |
| 84 | Mineral absorption_Homo sapiens_hsa04978 | 0.59141561 |
| 85 | Peroxisome_Homo sapiens_hsa04146 | 0.57693011 |
| 86 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.52561462 |
| 87 | Metabolic pathways_Homo sapiens_hsa01100 | 0.51671778 |
| 88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50351322 |
| 89 | Retinol metabolism_Homo sapiens_hsa00830 | 0.47419804 |
| 90 | Bile secretion_Homo sapiens_hsa04976 | 0.46290228 |
| 91 | Sulfur relay system_Homo sapiens_hsa04122 | 0.45705659 |
| 92 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.45518461 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43272200 |
| 94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.42446488 |
| 95 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41931422 |
| 96 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.37972769 |
| 97 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.35924056 |
| 98 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.35142691 |
| 99 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.34819042 |
| 100 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.32394593 |

