

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | hematopoietic stem cell differentiation (GO:0060218) | 9.43213833 |
| 2 | base-excision repair, AP site formation (GO:0006285) | 6.71211825 |
| 3 | cerebral cortex radially oriented cell migration (GO:0021799) | 6.29052527 |
| 4 | sulfate transmembrane transport (GO:1902358) | 6.03157253 |
| 5 | protein polyglutamylation (GO:0018095) | 5.68122432 |
| 6 | sulfate transport (GO:0008272) | 5.39975839 |
| 7 | cholesterol catabolic process (GO:0006707) | 5.21758641 |
| 8 | sterol catabolic process (GO:0016127) | 5.21758641 |
| 9 | mitochondrial calcium ion homeostasis (GO:0051560) | 4.96513648 |
| 10 | virion assembly (GO:0019068) | 4.70909720 |
| 11 | protein K6-linked ubiquitination (GO:0085020) | 4.69679077 |
| 12 | viral protein processing (GO:0019082) | 4.62606091 |
| 13 | acrosome assembly (GO:0001675) | 4.52742780 |
| 14 | mRNA modification (GO:0016556) | 4.51190491 |
| 15 | seminiferous tubule development (GO:0072520) | 4.49163352 |
| 16 | response to gravity (GO:0009629) | 4.47348586 |
| 17 | regulation of cholesterol homeostasis (GO:2000188) | 4.44170369 |
| 18 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 4.28530666 |
| 19 | DNA damage response, detection of DNA damage (GO:0042769) | 4.26991613 |
| 20 | positive regulation of mitochondrial membrane permeability (GO:0035794) | 4.24127180 |
| 21 | cytidine deamination (GO:0009972) | 4.17376786 |
| 22 | cytidine metabolic process (GO:0046087) | 4.17376786 |
| 23 | cytidine catabolic process (GO:0006216) | 4.17376786 |
| 24 | melanocyte differentiation (GO:0030318) | 4.10925086 |
| 25 | negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) | 4.05803502 |
| 26 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.99309216 |
| 27 | detection of light stimulus involved in visual perception (GO:0050908) | 3.90044777 |
| 28 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.90044777 |
| 29 | behavioral response to nicotine (GO:0035095) | 3.90035311 |
| 30 | positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) | 3.85023756 |
| 31 | regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) | 3.85023756 |
| 32 | pigment cell differentiation (GO:0050931) | 3.79926492 |
| 33 | regulation of synapse maturation (GO:0090128) | 3.77084723 |
| 34 | cell proliferation in forebrain (GO:0021846) | 3.65822249 |
| 35 | dicarboxylic acid catabolic process (GO:0043649) | 3.65550179 |
| 36 | negative regulation of keratinocyte proliferation (GO:0010839) | 3.65045470 |
| 37 | dopamine transport (GO:0015872) | 3.59931667 |
| 38 | mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) | 3.51591247 |
| 39 | positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110 | 3.51591247 |
| 40 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.48490973 |
| 41 | regulation of MHC class I biosynthetic process (GO:0045343) | 3.47453667 |
| 42 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.45001740 |
| 43 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.43319214 |
| 44 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.43319214 |
| 45 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 3.40639210 |
| 46 | regulation of megakaryocyte differentiation (GO:0045652) | 3.40396975 |
| 47 | cellular response to ATP (GO:0071318) | 3.38439675 |
| 48 | alkaloid metabolic process (GO:0009820) | 3.36295714 |
| 49 | regulation of protein glycosylation (GO:0060049) | 3.34866520 |
| 50 | lipoprotein transport (GO:0042953) | 3.34803518 |
| 51 | DNA double-strand break processing (GO:0000729) | 3.34453530 |
| 52 | TOR signaling (GO:0031929) | 3.29129146 |
| 53 | signal peptide processing (GO:0006465) | 3.27796273 |
| 54 | embryonic digestive tract morphogenesis (GO:0048557) | 3.26727445 |
| 55 | sodium-independent organic anion transport (GO:0043252) | 3.26337811 |
| 56 | base-excision repair (GO:0006284) | 3.25823204 |
| 57 | mammary gland epithelial cell proliferation (GO:0033598) | 3.23463431 |
| 58 | regulation of ER to Golgi vesicle-mediated transport (GO:0060628) | 3.22063039 |
| 59 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.20831415 |
| 60 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.20497467 |
| 61 | regulation of metalloenzyme activity (GO:0048552) | 3.19057154 |
| 62 | protein-cofactor linkage (GO:0018065) | 3.17502990 |
| 63 | regulation of cilium movement (GO:0003352) | 3.16897357 |
| 64 | positive regulation of protein kinase C signaling (GO:0090037) | 3.14857210 |
| 65 | positive regulation of erythrocyte differentiation (GO:0045648) | 3.13409675 |
| 66 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 3.13309205 |
| 67 | histone deubiquitination (GO:0016578) | 3.10831801 |
| 68 | neural tube formation (GO:0001841) | 3.09835635 |
| 69 | keratinocyte development (GO:0003334) | 3.07586367 |
| 70 | regulation of cell migration involved in sprouting angiogenesis (GO:0090049) | 3.06857292 |
| 71 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 3.05144725 |
| 72 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 3.04523696 |
| 73 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 3.04523696 |
| 74 | positive regulation of megakaryocyte differentiation (GO:0045654) | 3.03551436 |
| 75 | mitochondrial genome maintenance (GO:0000002) | 3.00520641 |
| 76 | entrainment of circadian clock (GO:0009649) | 2.97792017 |
| 77 | entrainment of circadian clock by photoperiod (GO:0043153) | 2.96851262 |
| 78 | neuroepithelial cell differentiation (GO:0060563) | 2.94808049 |
| 79 | negative regulation of actin filament bundle assembly (GO:0032232) | 2.94646618 |
| 80 | regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process (GO:2 | 2.94433527 |
| 81 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 2.87172380 |
| 82 | regulation of beta-amyloid formation (GO:1902003) | 2.85331327 |
| 83 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 2.84903154 |
| 84 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 2.84903154 |
| 85 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.84803326 |
| 86 | Peyers patch development (GO:0048541) | 2.84803326 |
| 87 | positive regulation of calcium ion import (GO:0090280) | 2.84096901 |
| 88 | adaptation of signaling pathway (GO:0023058) | 2.83729291 |
| 89 | amino acid salvage (GO:0043102) | 2.82439565 |
| 90 | L-methionine salvage (GO:0071267) | 2.82439565 |
| 91 | L-methionine biosynthetic process (GO:0071265) | 2.82439565 |
| 92 | cerebral cortex cell migration (GO:0021795) | 2.81058390 |
| 93 | retinal cone cell development (GO:0046549) | 2.80766213 |
| 94 | positive regulation of astrocyte differentiation (GO:0048711) | 2.80476066 |
| 95 | positive regulation of extracellular matrix organization (GO:1903055) | 2.79998641 |
| 96 | cellular response to reactive nitrogen species (GO:1902170) | 2.77840683 |
| 97 | sulfur compound transport (GO:0072348) | 2.77499419 |
| 98 | steroid catabolic process (GO:0006706) | 2.76067818 |
| 99 | L-fucose catabolic process (GO:0042355) | 2.75226882 |
| 100 | L-fucose metabolic process (GO:0042354) | 2.75226882 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 6.70669821 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 6.23154584 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.45950015 |
| 4 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.05941801 |
| 5 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.77272152 |
| 6 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 3.48723219 |
| 7 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 3.48723219 |
| 8 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 3.48723219 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.22625613 |
| 10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.70623085 |
| 11 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.67059211 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.60833641 |
| 13 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 2.46811088 |
| 14 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.37612354 |
| 15 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 2.36977842 |
| 16 | VDR_22108803_ChIP-Seq_LS180_Human | 2.13683479 |
| 17 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.86340538 |
| 18 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.71540559 |
| 19 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.66879430 |
| 20 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.62954677 |
| 21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.61995975 |
| 22 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.53261258 |
| 23 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.51226419 |
| 24 | FUS_26573619_Chip-Seq_HEK293_Human | 1.49540891 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.44666679 |
| 26 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.44564762 |
| 27 | P300_19829295_ChIP-Seq_ESCs_Human | 1.44533633 |
| 28 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.42994905 |
| 29 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.41117958 |
| 30 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.41024782 |
| 31 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.38880150 |
| 32 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.37673177 |
| 33 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.36898704 |
| 34 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.35561266 |
| 35 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.33145032 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.32978480 |
| 37 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.31279591 |
| 38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.28507290 |
| 39 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.27707452 |
| 40 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.27707452 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.27532789 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25795781 |
| 43 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.22227781 |
| 44 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.21287958 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.19961179 |
| 46 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.16663744 |
| 47 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.16145271 |
| 48 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.15771656 |
| 49 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.15676861 |
| 50 | AR_25329375_ChIP-Seq_VCAP_Human | 1.14349035 |
| 51 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.14183734 |
| 52 | JUN_21703547_ChIP-Seq_K562_Human | 1.13363078 |
| 53 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.13224652 |
| 54 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.12218000 |
| 55 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.11481211 |
| 56 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10165537 |
| 57 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.07957936 |
| 58 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.06707203 |
| 59 | STAT3_23295773_ChIP-Seq_U87_Human | 1.06374882 |
| 60 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.05379909 |
| 61 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.05275213 |
| 62 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04023816 |
| 63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.02092267 |
| 64 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.01996197 |
| 65 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.01440068 |
| 66 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.01419691 |
| 67 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.00599513 |
| 68 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.98815205 |
| 69 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97128142 |
| 70 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97128142 |
| 71 | CJUN_26792858_Chip-Seq_BT549_Human | 0.94636707 |
| 72 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.93911082 |
| 73 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.93130410 |
| 74 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.92510385 |
| 75 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.91712056 |
| 76 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.90878872 |
| 77 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.89820228 |
| 78 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.89628540 |
| 79 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.88568146 |
| 80 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.88407390 |
| 81 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.88225825 |
| 82 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.87452167 |
| 83 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 0.86675395 |
| 84 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.86005451 |
| 85 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.85294367 |
| 86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.85167995 |
| 87 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.84950113 |
| 88 | GATA3_26560356_Chip-Seq_TH2_Human | 0.84376977 |
| 89 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.82025085 |
| 90 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.81674842 |
| 91 | BRD4_25478319_ChIP-Seq_HGPS_Human | 0.81028610 |
| 92 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.80808440 |
| 93 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.80683364 |
| 94 | EWS_26573619_Chip-Seq_HEK293_Human | 0.80356252 |
| 95 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.80205723 |
| 96 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.79718277 |
| 97 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.79556006 |
| 98 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.79303690 |
| 99 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.78553238 |
| 100 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.77270812 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000013_abnormal_adipose_tissue | 8.20389913 |
| 2 | MP0008004_abnormal_stomach_pH | 7.60078917 |
| 3 | MP0000003_abnormal_adipose_tissue | 4.83402826 |
| 4 | MP0001984_abnormal_olfaction | 3.22283817 |
| 5 | MP0001502_abnormal_circadian_rhythm | 3.10792560 |
| 6 | MP0002736_abnormal_nociception_after | 2.95805187 |
| 7 | MP0003787_abnormal_imprinting | 2.95652602 |
| 8 | MP0001986_abnormal_taste_sensitivity | 2.33727931 |
| 9 | MP0001501_abnormal_sleep_pattern | 2.14778096 |
| 10 | MP0006054_spinal_hemorrhage | 2.11972619 |
| 11 | MP0005551_abnormal_eye_electrophysiolog | 2.08755637 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.06664191 |
| 13 | MP0004885_abnormal_endolymph | 2.05456345 |
| 14 | MP0002933_joint_inflammation | 2.01386072 |
| 15 | MP0006072_abnormal_retinal_apoptosis | 1.90524325 |
| 16 | MP0009250_abnormal_appendicular_skeleto | 1.61692907 |
| 17 | MP0004742_abnormal_vestibular_system | 1.59540271 |
| 18 | MP0000371_diluted_coat_color | 1.58842229 |
| 19 | MP0000538_abnormal_urinary_bladder | 1.56922445 |
| 20 | MP0008961_abnormal_basal_metabolism | 1.55548667 |
| 21 | MP0003195_calcinosis | 1.54747057 |
| 22 | MP0003950_abnormal_plasma_membrane | 1.52942115 |
| 23 | MP0006292_abnormal_olfactory_placode | 1.52123222 |
| 24 | MP0005375_adipose_tissue_phenotype | 1.48500593 |
| 25 | MP0004484_altered_response_of | 1.41898603 |
| 26 | MP0005253_abnormal_eye_physiology | 1.39865689 |
| 27 | MP0008875_abnormal_xenobiotic_pharmacok | 1.37970251 |
| 28 | MP0004233_abnormal_muscle_weight | 1.37704940 |
| 29 | MP0004145_abnormal_muscle_electrophysio | 1.36616457 |
| 30 | MP0001486_abnormal_startle_reflex | 1.34888788 |
| 31 | MP0001485_abnormal_pinna_reflex | 1.29912995 |
| 32 | MP0002733_abnormal_thermal_nociception | 1.26244743 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.20913034 |
| 34 | MP0003693_abnormal_embryo_hatching | 1.19696614 |
| 35 | MP0005367_renal/urinary_system_phenotyp | 1.17420318 |
| 36 | MP0000516_abnormal_urinary_system | 1.17420318 |
| 37 | MP0000427_abnormal_hair_cycle | 1.16973097 |
| 38 | MP0004142_abnormal_muscle_tone | 1.16285545 |
| 39 | MP0009278_abnormal_bone_marrow | 1.14521943 |
| 40 | MP0009046_muscle_twitch | 1.14446379 |
| 41 | MP0003011_delayed_dark_adaptation | 1.11780098 |
| 42 | MP0008877_abnormal_DNA_methylation | 1.07495381 |
| 43 | MP0010307_abnormal_tumor_latency | 1.05462144 |
| 44 | MP0002572_abnormal_emotion/affect_behav | 1.04269300 |
| 45 | MP0005410_abnormal_fertilization | 1.00477561 |
| 46 | MP0001970_abnormal_pain_threshold | 0.97653739 |
| 47 | MP0001440_abnormal_grooming_behavior | 0.97569305 |
| 48 | MP0000470_abnormal_stomach_morphology | 0.97208969 |
| 49 | MP0002735_abnormal_chemical_nociception | 0.95815519 |
| 50 | MP0008058_abnormal_DNA_repair | 0.93771386 |
| 51 | MP0005377_hearing/vestibular/ear_phenot | 0.92995145 |
| 52 | MP0003878_abnormal_ear_physiology | 0.92995145 |
| 53 | MP0005076_abnormal_cell_differentiation | 0.89159930 |
| 54 | MP0002234_abnormal_pharynx_morphology | 0.85391798 |
| 55 | MP0002653_abnormal_ependyma_morphology | 0.83081390 |
| 56 | MP0008872_abnormal_physiological_respon | 0.80978311 |
| 57 | MP0010368_abnormal_lymphatic_system | 0.79146829 |
| 58 | MP0005386_behavior/neurological_phenoty | 0.78338949 |
| 59 | MP0004924_abnormal_behavior | 0.78338949 |
| 60 | MP0010329_abnormal_lipoprotein_level | 0.76475120 |
| 61 | MP0002272_abnormal_nervous_system | 0.75608892 |
| 62 | MP0003635_abnormal_synaptic_transmissio | 0.74933504 |
| 63 | MP0004019_abnormal_vitamin_homeostasis | 0.74703384 |
| 64 | MP0003121_genomic_imprinting | 0.70750987 |
| 65 | MP0003646_muscle_fatigue | 0.69942010 |
| 66 | MP0003879_abnormal_hair_cell | 0.69791179 |
| 67 | MP0001919_abnormal_reproductive_system | 0.68979422 |
| 68 | MP0009115_abnormal_fat_cell | 0.67249223 |
| 69 | MP0005671_abnormal_response_to | 0.67005318 |
| 70 | MP0010386_abnormal_urinary_bladder | 0.66279379 |
| 71 | MP0002876_abnormal_thyroid_physiology | 0.65753693 |
| 72 | MP0002896_abnormal_bone_mineralization | 0.65420027 |
| 73 | MP0005334_abnormal_fat_pad | 0.65110843 |
| 74 | MP0009745_abnormal_behavioral_response | 0.64596239 |
| 75 | MP0000627_abnormal_mammary_gland | 0.64419946 |
| 76 | MP0002210_abnormal_sex_determination | 0.64298502 |
| 77 | MP0002135_abnormal_kidney_morphology | 0.63614980 |
| 78 | MP0002557_abnormal_social/conspecific_i | 0.61015135 |
| 79 | MP0003718_maternal_effect | 0.59865688 |
| 80 | MP0005310_abnormal_salivary_gland | 0.59496595 |
| 81 | MP0009764_decreased_sensitivity_to | 0.58443607 |
| 82 | MP0000631_abnormal_neuroendocrine_gland | 0.58219655 |
| 83 | MP0002638_abnormal_pupillary_reflex | 0.58206016 |
| 84 | MP0001800_abnormal_humoral_immune | 0.57812473 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.56642800 |
| 86 | MP0002229_neurodegeneration | 0.56271193 |
| 87 | MP0002064_seizures | 0.56212278 |
| 88 | MP0001929_abnormal_gametogenesis | 0.56158766 |
| 89 | MP0002118_abnormal_lipid_homeostasis | 0.53748235 |
| 90 | MP0001666_abnormal_nutrient_absorption | 0.52549276 |
| 91 | MP0005332_abnormal_amino_acid | 0.49908456 |
| 92 | MP0002063_abnormal_learning/memory/cond | 0.49788383 |
| 93 | MP0005452_abnormal_adipose_tissue | 0.49503870 |
| 94 | MP0002067_abnormal_sensory_capabilities | 0.49358392 |
| 95 | MP0001764_abnormal_homeostasis | 0.47324394 |
| 96 | MP0000579_abnormal_nail_morphology | 0.46932342 |
| 97 | MP0002136_abnormal_kidney_physiology | 0.46883459 |
| 98 | MP0000653_abnormal_sex_gland | 0.46848208 |
| 99 | MP0008995_early_reproductive_senescence | 0.46731228 |
| 100 | MP0002282_abnormal_trachea_morphology | 0.46260702 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Stomach cancer (HP:0012126) | 6.00978314 |
| 2 | Renal cortical cysts (HP:0000803) | 5.70602295 |
| 3 | Generalized hypopigmentation of hair (HP:0011358) | 5.02347938 |
| 4 | Abnormality of the renal cortex (HP:0011035) | 4.87661928 |
| 5 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 4.86691233 |
| 6 | Hypoplasia of the fovea (HP:0007750) | 4.86691233 |
| 7 | Prominent supraorbital ridges (HP:0000336) | 4.59014122 |
| 8 | Abnormality of lateral ventricle (HP:0030047) | 4.10524789 |
| 9 | Colon cancer (HP:0003003) | 4.02254555 |
| 10 | Anterior segment dysgenesis (HP:0007700) | 3.96357618 |
| 11 | Abnormality of the fovea (HP:0000493) | 3.66267962 |
| 12 | Woolly hair (HP:0002224) | 3.60264918 |
| 13 | Chronic hepatic failure (HP:0100626) | 3.45751562 |
| 14 | Proximal amyotrophy (HP:0007126) | 3.36480805 |
| 15 | Abnormal hair laboratory examination (HP:0003328) | 3.30565432 |
| 16 | Intellectual disability, moderate (HP:0002342) | 3.16656478 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.16023780 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.16023780 |
| 19 | Generalized hypopigmentation (HP:0007513) | 3.13370369 |
| 20 | Vacuolated lymphocytes (HP:0001922) | 3.12923509 |
| 21 | Conical tooth (HP:0000698) | 3.02530388 |
| 22 | Hypoalbuminemia (HP:0003073) | 2.96675714 |
| 23 | Abnormal albumin level (HP:0012116) | 2.96675714 |
| 24 | Abnormality of the renal medulla (HP:0100957) | 2.88191129 |
| 25 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.87153265 |
| 26 | Volvulus (HP:0002580) | 2.79542481 |
| 27 | Molar tooth sign on MRI (HP:0002419) | 2.77791122 |
| 28 | Abnormality of midbrain morphology (HP:0002418) | 2.77791122 |
| 29 | Polyuria (HP:0000103) | 2.72727426 |
| 30 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.63934588 |
| 31 | Hypoplastic labia majora (HP:0000059) | 2.63756783 |
| 32 | Polydipsia (HP:0001959) | 2.61086621 |
| 33 | Abnormal drinking behavior (HP:0030082) | 2.61086621 |
| 34 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.56293504 |
| 35 | Overlapping toe (HP:0001845) | 2.53764012 |
| 36 | Congenital, generalized hypertrichosis (HP:0004540) | 2.45484372 |
| 37 | Abnormality of the labia majora (HP:0012881) | 2.43898246 |
| 38 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.41331067 |
| 39 | Prominent forehead (HP:0011220) | 2.40951146 |
| 40 | Wormian bones (HP:0002645) | 2.40941453 |
| 41 | Congenital stationary night blindness (HP:0007642) | 2.39922935 |
| 42 | True hermaphroditism (HP:0010459) | 2.39383897 |
| 43 | Curly hair (HP:0002212) | 2.35127082 |
| 44 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.35024439 |
| 45 | Nephronophthisis (HP:0000090) | 2.34958611 |
| 46 | Ocular albinism (HP:0001107) | 2.33636233 |
| 47 | Abnormality of methionine metabolism (HP:0010901) | 2.31070863 |
| 48 | Chorioretinal coloboma (HP:0000567) | 2.30584533 |
| 49 | Nausea (HP:0002018) | 2.28792430 |
| 50 | Scrotal hypoplasia (HP:0000046) | 2.28159380 |
| 51 | Thrombocytosis (HP:0001894) | 2.25517949 |
| 52 | Abnormal urine output (HP:0012590) | 2.24949955 |
| 53 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.24190949 |
| 54 | Flat capital femoral epiphysis (HP:0003370) | 2.23016943 |
| 55 | Abnormal number of incisors (HP:0011064) | 2.21907847 |
| 56 | Absent speech (HP:0001344) | 2.18514548 |
| 57 | Brittle hair (HP:0002299) | 2.18148819 |
| 58 | Patellar aplasia (HP:0006443) | 2.17115287 |
| 59 | Abnormality of dental color (HP:0011073) | 2.15214162 |
| 60 | Hyperaldosteronism (HP:0000859) | 2.14831207 |
| 61 | Abnormality of small intestinal villus morphology (HP:0011472) | 2.13103293 |
| 62 | Villous atrophy (HP:0011473) | 2.13103293 |
| 63 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.11764483 |
| 64 | Thyroid-stimulating hormone excess (HP:0002925) | 2.11413304 |
| 65 | Neoplasm of the oral cavity (HP:0100649) | 2.08826117 |
| 66 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.04786793 |
| 67 | Febrile seizures (HP:0002373) | 2.04527460 |
| 68 | Broad alveolar ridges (HP:0000187) | 2.02437200 |
| 69 | Tracheomalacia (HP:0002779) | 2.01561485 |
| 70 | Subacute progressive viral hepatitis (HP:0006572) | 2.01274736 |
| 71 | IgG deficiency (HP:0004315) | 2.00970474 |
| 72 | Hepatocellular necrosis (HP:0001404) | 1.99126289 |
| 73 | Hypoplasia of the thymus (HP:0000778) | 1.97986602 |
| 74 | Small epiphyses (HP:0010585) | 1.96614349 |
| 75 | Broad-based gait (HP:0002136) | 1.94713958 |
| 76 | Pancreatic cysts (HP:0001737) | 1.94454959 |
| 77 | Tetraplegia (HP:0002445) | 1.94000882 |
| 78 | Chronic diarrhea (HP:0002028) | 1.92021288 |
| 79 | Iris hypopigmentation (HP:0007730) | 1.91510998 |
| 80 | Abnormality of alanine metabolism (HP:0010916) | 1.91134917 |
| 81 | Hyperalaninemia (HP:0003348) | 1.91134917 |
| 82 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.91134917 |
| 83 | Hypokalemic alkalosis (HP:0001949) | 1.88963034 |
| 84 | Abnormality of the incisor (HP:0000676) | 1.87399527 |
| 85 | Abnormality of macular pigmentation (HP:0008002) | 1.87263054 |
| 86 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.87099680 |
| 87 | Abnormality of renal excretion (HP:0011036) | 1.86715790 |
| 88 | Pancreatic fibrosis (HP:0100732) | 1.85712725 |
| 89 | Optic nerve hypoplasia (HP:0000609) | 1.82172939 |
| 90 | Autoimmune hemolytic anemia (HP:0001890) | 1.82062464 |
| 91 | Optic disc pallor (HP:0000543) | 1.82010978 |
| 92 | Abnormal number of erythroid precursors (HP:0012131) | 1.81604542 |
| 93 | Abnormal gallbladder physiology (HP:0012438) | 1.81490887 |
| 94 | Cholecystitis (HP:0001082) | 1.81490887 |
| 95 | Postnatal microcephaly (HP:0005484) | 1.79221979 |
| 96 | Aortic regurgitation (HP:0001659) | 1.79208815 |
| 97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78400239 |
| 98 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.76538529 |
| 99 | Sclerocornea (HP:0000647) | 1.74012454 |
| 100 | Abnormality of iron homeostasis (HP:0011031) | 1.73753190 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CASK | 7.97034137 |
| 2 | TLK1 | 7.00095718 |
| 3 | ZAK | 6.13586484 |
| 4 | TRIM28 | 3.05645181 |
| 5 | BCKDK | 2.70031151 |
| 6 | PDK2 | 2.45703565 |
| 7 | VRK1 | 2.28505521 |
| 8 | CCNB1 | 2.22495615 |
| 9 | EPHA3 | 2.11860707 |
| 10 | MST4 | 1.98807521 |
| 11 | KDR | 1.97809460 |
| 12 | PNCK | 1.94779365 |
| 13 | WNK3 | 1.81975955 |
| 14 | PHKG1 | 1.65055137 |
| 15 | PHKG2 | 1.65055137 |
| 16 | NEK6 | 1.50926360 |
| 17 | FLT3 | 1.46663865 |
| 18 | WEE1 | 1.41806849 |
| 19 | PKN1 | 1.36516583 |
| 20 | NUAK1 | 1.33279206 |
| 21 | STK38L | 1.31401239 |
| 22 | TSSK6 | 1.28437171 |
| 23 | PRKD3 | 1.27270171 |
| 24 | FRK | 1.14703993 |
| 25 | DAPK2 | 1.12841515 |
| 26 | RPS6KA5 | 1.12803301 |
| 27 | VRK2 | 1.07894378 |
| 28 | PIM1 | 1.05974063 |
| 29 | STK39 | 1.02414298 |
| 30 | CDK12 | 0.93089611 |
| 31 | STK24 | 0.91979245 |
| 32 | WNK4 | 0.91628262 |
| 33 | GRK5 | 0.86500684 |
| 34 | IKBKB | 0.85275472 |
| 35 | TNIK | 0.81239587 |
| 36 | MKNK2 | 0.76109433 |
| 37 | PRKCQ | 0.68877983 |
| 38 | DYRK2 | 0.68520069 |
| 39 | PINK1 | 0.61111330 |
| 40 | MAP4K2 | 0.60911982 |
| 41 | SIK3 | 0.60037283 |
| 42 | MAP3K14 | 0.58751387 |
| 43 | MAPK13 | 0.57416530 |
| 44 | MAPKAPK5 | 0.55867770 |
| 45 | CAMKK2 | 0.55530367 |
| 46 | DAPK1 | 0.53808785 |
| 47 | ROCK1 | 0.52770808 |
| 48 | MAP2K2 | 0.52638018 |
| 49 | PRKCI | 0.52091948 |
| 50 | MAPKAPK3 | 0.48877979 |
| 51 | OXSR1 | 0.48830137 |
| 52 | AKT2 | 0.46894960 |
| 53 | JAK1 | 0.46149856 |
| 54 | CHUK | 0.42170551 |
| 55 | CHEK2 | 0.41231688 |
| 56 | MAP3K12 | 0.40901317 |
| 57 | PRKAA1 | 0.40045202 |
| 58 | CDK6 | 0.39382574 |
| 59 | MKNK1 | 0.39028595 |
| 60 | BRSK2 | 0.37428501 |
| 61 | STK4 | 0.36782043 |
| 62 | ADRBK1 | 0.36177018 |
| 63 | BMPR2 | 0.33202201 |
| 64 | MAPK14 | 0.32066074 |
| 65 | IKBKE | 0.31581541 |
| 66 | MAPK7 | 0.29662304 |
| 67 | NTRK1 | 0.29462845 |
| 68 | LRRK2 | 0.28768964 |
| 69 | MAP3K5 | 0.28523306 |
| 70 | CAMK1G | 0.28288770 |
| 71 | PLK4 | 0.27683458 |
| 72 | TAF1 | 0.27438204 |
| 73 | PRKAA2 | 0.27362435 |
| 74 | MARK1 | 0.27050822 |
| 75 | DAPK3 | 0.25236679 |
| 76 | NLK | 0.24805310 |
| 77 | MAPK9 | 0.23663848 |
| 78 | MELK | 0.23563298 |
| 79 | GRK1 | 0.23408323 |
| 80 | CSNK1A1L | 0.22839638 |
| 81 | CDK4 | 0.22387750 |
| 82 | RPS6KA6 | 0.21010631 |
| 83 | MET | 0.20324237 |
| 84 | ERBB4 | 0.19973139 |
| 85 | CSNK1G3 | 0.19947236 |
| 86 | PIK3CA | 0.18399698 |
| 87 | GRK7 | 0.17101425 |
| 88 | BMPR1B | 0.16004163 |
| 89 | TAOK3 | 0.15591790 |
| 90 | STK10 | 0.14785090 |
| 91 | LATS2 | 0.14726075 |
| 92 | PKN2 | 0.13872554 |
| 93 | EIF2AK2 | 0.13535098 |
| 94 | RPS6KA2 | 0.13240757 |
| 95 | RPS6KA1 | 0.12002903 |
| 96 | TRPM7 | 0.11948228 |
| 97 | HIPK2 | 0.11883587 |
| 98 | TIE1 | 0.11568845 |
| 99 | DYRK1A | 0.11531518 |
| 100 | NTRK2 | 0.11077358 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Base excision repair_Homo sapiens_hsa03410 | 4.41146432 |
| 2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.29925290 |
| 3 | Caffeine metabolism_Homo sapiens_hsa00232 | 3.08596815 |
| 4 | Selenocompound metabolism_Homo sapiens_hsa00450 | 2.85136512 |
| 5 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.75360098 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.48762723 |
| 7 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.24194044 |
| 8 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.10558544 |
| 9 | Proteasome_Homo sapiens_hsa03050 | 1.89564409 |
| 10 | Circadian rhythm_Homo sapiens_hsa04710 | 1.88721394 |
| 11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.87134529 |
| 12 | Mineral absorption_Homo sapiens_hsa04978 | 1.79530780 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 1.60918438 |
| 14 | Alcoholism_Homo sapiens_hsa05034 | 1.52478513 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.51021234 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.50738377 |
| 17 | Retinol metabolism_Homo sapiens_hsa00830 | 1.49670862 |
| 18 | Nicotine addiction_Homo sapiens_hsa05033 | 1.48332958 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.46863004 |
| 20 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.44292045 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.44206025 |
| 22 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.40383375 |
| 23 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.39485075 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.36616338 |
| 25 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.33950400 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.33642987 |
| 27 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.31952320 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.29013597 |
| 29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.28995190 |
| 30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.25941377 |
| 31 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.21177806 |
| 32 | Parkinsons disease_Homo sapiens_hsa05012 | 1.17335146 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.16871873 |
| 34 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.16678178 |
| 35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.15788551 |
| 36 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.14979580 |
| 37 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.14966466 |
| 38 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.14328027 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.11204071 |
| 40 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.08894794 |
| 41 | Lysine degradation_Homo sapiens_hsa00310 | 1.06979156 |
| 42 | Salivary secretion_Homo sapiens_hsa04970 | 1.05480405 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.03248296 |
| 44 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.02730376 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.02379931 |
| 46 | RNA polymerase_Homo sapiens_hsa03020 | 0.94967959 |
| 47 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.94676891 |
| 48 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.94283189 |
| 49 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.94242684 |
| 50 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.88943524 |
| 51 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.88648805 |
| 52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.85326058 |
| 53 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.84977097 |
| 54 | Morphine addiction_Homo sapiens_hsa05032 | 0.83237467 |
| 55 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.82985114 |
| 56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.82446977 |
| 57 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.81829754 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.81015650 |
| 59 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.79114043 |
| 60 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.78391008 |
| 61 | Alzheimers disease_Homo sapiens_hsa05010 | 0.76259887 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.75598604 |
| 63 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.74047497 |
| 64 | Circadian entrainment_Homo sapiens_hsa04713 | 0.72093017 |
| 65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.72035876 |
| 66 | Huntingtons disease_Homo sapiens_hsa05016 | 0.68889946 |
| 67 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.67833300 |
| 68 | Taste transduction_Homo sapiens_hsa04742 | 0.64917144 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.64689926 |
| 70 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.64031501 |
| 71 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.63284324 |
| 72 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.61940402 |
| 73 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.61213748 |
| 74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60807821 |
| 75 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.59770657 |
| 76 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.57321382 |
| 77 | Insulin secretion_Homo sapiens_hsa04911 | 0.56116088 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.55888450 |
| 79 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53912374 |
| 80 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53138571 |
| 81 | Histidine metabolism_Homo sapiens_hsa00340 | 0.53040497 |
| 82 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.52307641 |
| 83 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.50362619 |
| 84 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.47729850 |
| 85 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.46840553 |
| 86 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.43831110 |
| 87 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.43659871 |
| 88 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.42527187 |
| 89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.40578247 |
| 90 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.39544542 |
| 91 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.37850852 |
| 92 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.37726649 |
| 93 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.33893185 |
| 94 | Spliceosome_Homo sapiens_hsa03040 | 0.33228953 |
| 95 | Ribosome_Homo sapiens_hsa03010 | 0.30591041 |
| 96 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.28974245 |
| 97 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.27495229 |
| 98 | GABAergic synapse_Homo sapiens_hsa04727 | 0.27422312 |
| 99 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.27245953 |
| 100 | Bile secretion_Homo sapiens_hsa04976 | 0.26959260 |

