

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine nucleobase catabolic process (GO:0006208) | 8.57631760 |
| 2 | cellular response to vitamin (GO:0071295) | 7.10154883 |
| 3 | nucleobase catabolic process (GO:0046113) | 7.00284743 |
| 4 | response to UV-C (GO:0010225) | 6.96101863 |
| 5 | melanin biosynthetic process (GO:0042438) | 6.69724832 |
| 6 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 6.63181240 |
| 7 | negative regulation of cell cycle arrest (GO:0071157) | 6.51820684 |
| 8 | melanin metabolic process (GO:0006582) | 6.20903317 |
| 9 | negative regulation of norepinephrine secretion (GO:0010700) | 6.11305879 |
| 10 | secondary metabolite biosynthetic process (GO:0044550) | 6.09144373 |
| 11 | embryonic camera-type eye development (GO:0031076) | 5.60003916 |
| 12 | hair cell differentiation (GO:0035315) | 5.54826205 |
| 13 | positive regulation of protein export from nucleus (GO:0046827) | 5.18210339 |
| 14 | response to magnesium ion (GO:0032026) | 5.07279267 |
| 15 | cell migration involved in heart development (GO:0060973) | 5.06062249 |
| 16 | positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) | 5.01755247 |
| 17 | venous blood vessel morphogenesis (GO:0048845) | 4.95892186 |
| 18 | cellular response to antibiotic (GO:0071236) | 4.90655732 |
| 19 | ketone body metabolic process (GO:1902224) | 4.75143996 |
| 20 | ventricular cardiac muscle cell development (GO:0055015) | 4.73888542 |
| 21 | positive regulation of cell cycle G1/S phase transition (GO:1902808) | 4.69875643 |
| 22 | lung morphogenesis (GO:0060425) | 4.68464749 |
| 23 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 4.65958450 |
| 24 | left/right axis specification (GO:0070986) | 4.60988224 |
| 25 | negative regulation of calcium ion-dependent exocytosis (GO:0045955) | 4.59198711 |
| 26 | central nervous system projection neuron axonogenesis (GO:0021952) | 4.26056158 |
| 27 | negative regulation of catecholamine secretion (GO:0033604) | 4.13024369 |
| 28 | cellular response to toxic substance (GO:0097237) | 4.11967238 |
| 29 | protein K11-linked deubiquitination (GO:0035871) | 4.08383520 |
| 30 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 4.00783960 |
| 31 | female gonad development (GO:0008585) | 3.91937862 |
| 32 | melanosome organization (GO:0032438) | 3.84620619 |
| 33 | regulation of penile erection (GO:0060405) | 3.71110691 |
| 34 | pigment granule organization (GO:0048753) | 3.70949985 |
| 35 | negative regulation of signal transduction by p53 class mediator (GO:1901797) | 3.58936040 |
| 36 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.53708410 |
| 37 | central nervous system neuron axonogenesis (GO:0021955) | 3.48342090 |
| 38 | male meiosis (GO:0007140) | 3.45357595 |
| 39 | ganglion development (GO:0061548) | 3.41222948 |
| 40 | ventricular septum morphogenesis (GO:0060412) | 3.38903761 |
| 41 | nerve growth factor signaling pathway (GO:0038180) | 3.38075106 |
| 42 | sympathetic nervous system development (GO:0048485) | 3.37726521 |
| 43 | synaptonemal complex assembly (GO:0007130) | 3.33737021 |
| 44 | exocrine pancreas development (GO:0031017) | 3.31014800 |
| 45 | synaptonemal complex organization (GO:0070193) | 3.27431894 |
| 46 | melanocyte differentiation (GO:0030318) | 3.26388974 |
| 47 | regulation of norepinephrine secretion (GO:0014061) | 3.23936537 |
| 48 | response to cocaine (GO:0042220) | 3.23885703 |
| 49 | phenol-containing compound biosynthetic process (GO:0046189) | 3.21610053 |
| 50 | olfactory bulb development (GO:0021772) | 3.20406485 |
| 51 | digestive tract morphogenesis (GO:0048546) | 3.17106065 |
| 52 | postsynaptic membrane organization (GO:0001941) | 3.14878851 |
| 53 | retinal ganglion cell axon guidance (GO:0031290) | 3.08729230 |
| 54 | piRNA metabolic process (GO:0034587) | 3.06746296 |
| 55 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 3.06497572 |
| 56 | response to iron ion (GO:0010039) | 3.05603464 |
| 57 | short-chain fatty acid metabolic process (GO:0046459) | 3.05178326 |
| 58 | dentate gyrus development (GO:0021542) | 3.04914710 |
| 59 | cellular response to nutrient (GO:0031670) | 3.04632305 |
| 60 | neuron recognition (GO:0008038) | 3.01830807 |
| 61 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.99687313 |
| 62 | UMP metabolic process (GO:0046049) | 2.99687313 |
| 63 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.99687313 |
| 64 | UMP biosynthetic process (GO:0006222) | 2.99687313 |
| 65 | peristalsis (GO:0030432) | 2.97380641 |
| 66 | response to vitamin A (GO:0033189) | 2.94269258 |
| 67 | neuroepithelial cell differentiation (GO:0060563) | 2.92291958 |
| 68 | pigment cell differentiation (GO:0050931) | 2.90889225 |
| 69 | myoblast fusion (GO:0007520) | 2.90614840 |
| 70 | protein destabilization (GO:0031648) | 2.90370175 |
| 71 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.87171236 |
| 72 | embryonic digestive tract morphogenesis (GO:0048557) | 2.86930815 |
| 73 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.85753561 |
| 74 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 2.84613237 |
| 75 | positive regulation of developmental pigmentation (GO:0048087) | 2.83478406 |
| 76 | DNA damage response, detection of DNA damage (GO:0042769) | 2.81732782 |
| 77 | regulation of protein export from nucleus (GO:0046825) | 2.80668137 |
| 78 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 2.79817490 |
| 79 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.79693951 |
| 80 | rRNA methylation (GO:0031167) | 2.78090052 |
| 81 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 2.75047783 |
| 82 | phasic smooth muscle contraction (GO:0014821) | 2.73400444 |
| 83 | inositol phosphate catabolic process (GO:0071545) | 2.73273415 |
| 84 | ncRNA catabolic process (GO:0034661) | 2.70735046 |
| 85 | regulation of telomere maintenance via telomerase (GO:0032210) | 2.69616138 |
| 86 | regulation of hexokinase activity (GO:1903299) | 2.69040455 |
| 87 | regulation of glucokinase activity (GO:0033131) | 2.69040455 |
| 88 | opioid receptor signaling pathway (GO:0038003) | 2.69018686 |
| 89 | cellular response to estrogen stimulus (GO:0071391) | 2.68322874 |
| 90 | neural crest cell migration (GO:0001755) | 2.66610037 |
| 91 | brain morphogenesis (GO:0048854) | 2.66575366 |
| 92 | replication fork processing (GO:0031297) | 2.65859017 |
| 93 | rRNA catabolic process (GO:0016075) | 2.64093677 |
| 94 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.63800285 |
| 95 | rRNA modification (GO:0000154) | 2.62993480 |
| 96 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.61451424 |
| 97 | neuron fate determination (GO:0048664) | 2.61245834 |
| 98 | positive regulation of DNA-dependent DNA replication (GO:2000105) | 2.61153535 |
| 99 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.60168803 |
| 100 | anterograde synaptic vesicle transport (GO:0048490) | 2.59716318 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.17638384 |
| 2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.36188910 |
| 3 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.35969516 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 2.99422829 |
| 5 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.80068333 |
| 6 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.71926890 |
| 7 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.58406150 |
| 8 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.55820112 |
| 9 | FUS_26573619_Chip-Seq_HEK293_Human | 2.47180466 |
| 10 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.42963971 |
| 11 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 2.42929054 |
| 12 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.25385824 |
| 13 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 2.19422920 |
| 14 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.19422920 |
| 15 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 2.17962645 |
| 16 | P300_19829295_ChIP-Seq_ESCs_Human | 2.16631990 |
| 17 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98038925 |
| 18 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.94559047 |
| 19 | EWS_26573619_Chip-Seq_HEK293_Human | 1.88944508 |
| 20 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.77197816 |
| 21 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.76016253 |
| 22 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.75280516 |
| 23 | TP53_16413492_ChIP-PET_HCT116_Human | 1.65565081 |
| 24 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.64459257 |
| 25 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.63864554 |
| 26 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.56891546 |
| 27 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.54448382 |
| 28 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.54292194 |
| 29 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.53455859 |
| 30 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.50523381 |
| 31 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.50437742 |
| 32 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.47707746 |
| 33 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.46311508 |
| 34 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.45356953 |
| 35 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.44601926 |
| 36 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.43644995 |
| 37 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.43038664 |
| 38 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.41287536 |
| 39 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.40241218 |
| 40 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.40110122 |
| 41 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.38640386 |
| 42 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.37864398 |
| 43 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.36588356 |
| 44 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.35708618 |
| 45 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.35645082 |
| 46 | STAT3_23295773_ChIP-Seq_U87_Human | 1.35505025 |
| 47 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.34686464 |
| 48 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.34092245 |
| 49 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.34049495 |
| 50 | AR_25329375_ChIP-Seq_VCAP_Human | 1.33806158 |
| 51 | RXR_22108803_ChIP-Seq_LS180_Human | 1.33786944 |
| 52 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.31881022 |
| 53 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31454186 |
| 54 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.29895091 |
| 55 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.28662760 |
| 56 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.28553502 |
| 57 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.26780865 |
| 58 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.26260212 |
| 59 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.24801494 |
| 60 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.18356689 |
| 61 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.17899076 |
| 62 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.17132262 |
| 63 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14850416 |
| 64 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.14150422 |
| 65 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.12176555 |
| 66 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.11794793 |
| 67 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.11475718 |
| 68 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.11460882 |
| 69 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.11213835 |
| 70 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.10285139 |
| 71 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.09971330 |
| 72 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09859668 |
| 73 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.09587198 |
| 74 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.09380235 |
| 75 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.09350881 |
| 76 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.08947800 |
| 77 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.08568204 |
| 78 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.08568204 |
| 79 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.08514510 |
| 80 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.08131106 |
| 81 | TCF4_23295773_ChIP-Seq_U87_Human | 1.07804254 |
| 82 | GF1B_26923725_Chip-Seq_HPCs_Mouse | 1.06556152 |
| 83 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.06503930 |
| 84 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.06223825 |
| 85 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.05777809 |
| 86 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.04374552 |
| 87 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.04031812 |
| 88 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.04003147 |
| 89 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.04003147 |
| 90 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.03850292 |
| 91 | NCOR_22424771_ChIP-Seq_293T_Human | 1.03397607 |
| 92 | JUN_21703547_ChIP-Seq_K562_Human | 1.02031448 |
| 93 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01732777 |
| 94 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.01207245 |
| 95 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99505142 |
| 96 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.99176704 |
| 97 | POU3F1_26484290_ChIP-Seq_ESCss_Mouse | 0.97597836 |
| 98 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.96579932 |
| 99 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.96561804 |
| 100 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.96212575 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 5.59109586 |
| 2 | MP0003878_abnormal_ear_physiology | 4.63306029 |
| 3 | MP0005377_hearing/vestibular/ear_phenot | 4.63306029 |
| 4 | MP0010030_abnormal_orbit_morphology | 4.31291125 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.83543597 |
| 6 | MP0000372_irregular_coat_pigmentation | 3.47231912 |
| 7 | MP0004133_heterotaxia | 3.07731805 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 2.81306557 |
| 9 | MP0003136_yellow_coat_color | 2.71712991 |
| 10 | MP0008789_abnormal_olfactory_epithelium | 2.63984128 |
| 11 | MP0004885_abnormal_endolymph | 2.57262965 |
| 12 | MP0000778_abnormal_nervous_system | 2.49707827 |
| 13 | MP0003221_abnormal_cardiomyocyte_apopto | 2.32134045 |
| 14 | MP0000569_abnormal_digit_pigmentation | 2.16377228 |
| 15 | MP0001299_abnormal_eye_distance/ | 2.09376481 |
| 16 | MP0002234_abnormal_pharynx_morphology | 2.06213748 |
| 17 | MP0000015_abnormal_ear_pigmentation | 2.05515561 |
| 18 | MP0005171_absent_coat_pigmentation | 1.98733936 |
| 19 | MP0005499_abnormal_olfactory_system | 1.97745406 |
| 20 | MP0005394_taste/olfaction_phenotype | 1.97745406 |
| 21 | MP0003137_abnormal_impulse_conducting | 1.90994711 |
| 22 | MP0002938_white_spotting | 1.86634663 |
| 23 | MP0001545_abnormal_hematopoietic_system | 1.72856542 |
| 24 | MP0005397_hematopoietic_system_phenotyp | 1.72856542 |
| 25 | MP0001324_abnormal_eye_pigmentation | 1.72468612 |
| 26 | MP0000631_abnormal_neuroendocrine_gland | 1.64239943 |
| 27 | MP0008872_abnormal_physiological_respon | 1.61808309 |
| 28 | MP0003880_abnormal_central_pattern | 1.60092622 |
| 29 | MP0005408_hypopigmentation | 1.57679417 |
| 30 | MP0000371_diluted_coat_color | 1.54247041 |
| 31 | MP0002095_abnormal_skin_pigmentation | 1.48894700 |
| 32 | MP0005197_abnormal_uvea_morphology | 1.47254577 |
| 33 | MP0000534_abnormal_ureter_morphology | 1.46409844 |
| 34 | MP0003755_abnormal_palate_morphology | 1.42048688 |
| 35 | MP0001984_abnormal_olfaction | 1.41377185 |
| 36 | MP0008877_abnormal_DNA_methylation | 1.39732505 |
| 37 | MP0001286_abnormal_eye_development | 1.29560265 |
| 38 | MP0005423_abnormal_somatic_nervous | 1.25429024 |
| 39 | MP0003186_abnormal_redox_activity | 1.24458474 |
| 40 | MP0003787_abnormal_imprinting | 1.21163072 |
| 41 | MP0002184_abnormal_innervation | 1.16181830 |
| 42 | MP0001293_anophthalmia | 1.09637178 |
| 43 | MP0005195_abnormal_posterior_eye | 1.08196185 |
| 44 | MP0002233_abnormal_nose_morphology | 1.04017661 |
| 45 | MP0000955_abnormal_spinal_cord | 1.03686167 |
| 46 | MP0005451_abnormal_body_composition | 1.02554685 |
| 47 | MP0000470_abnormal_stomach_morphology | 1.01177677 |
| 48 | MP0002653_abnormal_ependyma_morphology | 1.00835962 |
| 49 | MP0005386_behavior/neurological_phenoty | 1.00318395 |
| 50 | MP0004924_abnormal_behavior | 1.00318395 |
| 51 | MP0005551_abnormal_eye_electrophysiolog | 1.00014002 |
| 52 | MP0004859_abnormal_synaptic_plasticity | 0.99576346 |
| 53 | MP0003942_abnormal_urinary_system | 0.99529142 |
| 54 | MP0009053_abnormal_anal_canal | 0.99214576 |
| 55 | MP0003635_abnormal_synaptic_transmissio | 0.99016106 |
| 56 | MP0008057_abnormal_DNA_replication | 0.97991976 |
| 57 | MP0001177_atelectasis | 0.97633935 |
| 58 | MP0002092_abnormal_eye_morphology | 0.97188628 |
| 59 | MP0003718_maternal_effect | 0.96717048 |
| 60 | MP0003385_abnormal_body_wall | 0.96269974 |
| 61 | MP0004085_abnormal_heartbeat | 0.96067387 |
| 62 | MP0002822_catalepsy | 0.93955934 |
| 63 | MP0005391_vision/eye_phenotype | 0.92589471 |
| 64 | MP0002752_abnormal_somatic_nervous | 0.91364284 |
| 65 | MP0001664_abnormal_digestion | 0.90912877 |
| 66 | MP0000049_abnormal_middle_ear | 0.90182493 |
| 67 | MP0004742_abnormal_vestibular_system | 0.89189928 |
| 68 | MP0009745_abnormal_behavioral_response | 0.88768038 |
| 69 | MP0005174_abnormal_tail_pigmentation | 0.88637737 |
| 70 | MP0002089_abnormal_postnatal_growth/wei | 0.87023447 |
| 71 | MP0002837_dystrophic_cardiac_calcinosis | 0.85991511 |
| 72 | MP0003861_abnormal_nervous_system | 0.85324402 |
| 73 | MP0002882_abnormal_neuron_morphology | 0.83023771 |
| 74 | MP0003938_abnormal_ear_development | 0.81281162 |
| 75 | MP0005220_abnormal_exocrine_pancreas | 0.78156069 |
| 76 | MP0002733_abnormal_thermal_nociception | 0.78088976 |
| 77 | MP0002272_abnormal_nervous_system | 0.78066401 |
| 78 | MP0002736_abnormal_nociception_after | 0.77917483 |
| 79 | MP0006072_abnormal_retinal_apoptosis | 0.77596255 |
| 80 | MP0003121_genomic_imprinting | 0.76865135 |
| 81 | MP0005253_abnormal_eye_physiology | 0.76224315 |
| 82 | MP0003122_maternal_imprinting | 0.74964984 |
| 83 | MP0000026_abnormal_inner_ear | 0.74467765 |
| 84 | MP0001963_abnormal_hearing_physiology | 0.73493719 |
| 85 | MP0004381_abnormal_hair_follicle | 0.72967944 |
| 86 | MP0003656_abnormal_erythrocyte_physiolo | 0.72518256 |
| 87 | MP0002751_abnormal_autonomic_nervous | 0.72299860 |
| 88 | MP0001486_abnormal_startle_reflex | 0.70303506 |
| 89 | MP0009379_abnormal_foot_pigmentation | 0.67732895 |
| 90 | MP0008775_abnormal_heart_ventricle | 0.67113290 |
| 91 | MP0001485_abnormal_pinna_reflex | 0.67083762 |
| 92 | MP0002735_abnormal_chemical_nociception | 0.67026525 |
| 93 | MP0000516_abnormal_urinary_system | 0.66518207 |
| 94 | MP0005367_renal/urinary_system_phenotyp | 0.66518207 |
| 95 | MP0002064_seizures | 0.66233777 |
| 96 | MP0002063_abnormal_learning/memory/cond | 0.65491141 |
| 97 | MP0004142_abnormal_muscle_tone | 0.64962095 |
| 98 | MP0002152_abnormal_brain_morphology | 0.64768858 |
| 99 | MP0001986_abnormal_taste_sensitivity | 0.63912436 |
| 100 | MP0001968_abnormal_touch/_nociception | 0.63867957 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Anterior segment dysgenesis (HP:0007700) | 6.98665512 |
| 2 | Neoplasm of the adrenal gland (HP:0100631) | 6.57222228 |
| 3 | Iris hypopigmentation (HP:0007730) | 6.12280171 |
| 4 | Hypoplasia of the iris (HP:0007676) | 4.31041981 |
| 5 | Ocular albinism (HP:0001107) | 4.17783165 |
| 6 | Focal motor seizures (HP:0011153) | 4.13177788 |
| 7 | Intestinal atresia (HP:0011100) | 3.73371806 |
| 8 | Anal stenosis (HP:0002025) | 3.57845532 |
| 9 | Focal seizures (HP:0007359) | 3.30913674 |
| 10 | Pancreatic fibrosis (HP:0100732) | 3.26345395 |
| 11 | Megalocornea (HP:0000485) | 3.20961408 |
| 12 | Gastrointestinal atresia (HP:0002589) | 3.10572289 |
| 13 | Melanoma (HP:0002861) | 3.08402626 |
| 14 | Tetraplegia (HP:0002445) | 3.06630922 |
| 15 | Growth hormone deficiency (HP:0000824) | 3.03666774 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 2.87442937 |
| 17 | Abnormality of midbrain morphology (HP:0002418) | 2.87442937 |
| 18 | Decreased subcutaneous fat (HP:0001002) | 2.78983805 |
| 19 | Metaphyseal dysplasia (HP:0100255) | 2.78962582 |
| 20 | Short chin (HP:0000331) | 2.71675375 |
| 21 | Acute necrotizing encephalopathy (HP:0006965) | 2.66979440 |
| 22 | Steatorrhea (HP:0002570) | 2.65942333 |
| 23 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.62342217 |
| 24 | Optic nerve hypoplasia (HP:0000609) | 2.61816609 |
| 25 | Anal atresia (HP:0002023) | 2.60644495 |
| 26 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.59557228 |
| 27 | Aplasia/Hypoplasia of the lens (HP:0008063) | 2.52327747 |
| 28 | Progressive macrocephaly (HP:0004481) | 2.46197281 |
| 29 | Neoplasm of the lung (HP:0100526) | 2.44933615 |
| 30 | Abnormality of the anterior chamber (HP:0000593) | 2.41527226 |
| 31 | Medial flaring of the eyebrow (HP:0010747) | 2.38705843 |
| 32 | Dialeptic seizures (HP:0011146) | 2.37028913 |
| 33 | Abnormality of subcutaneous fat tissue (HP:0001001) | 2.36030912 |
| 34 | Congenital stationary night blindness (HP:0007642) | 2.30431241 |
| 35 | Neoplasm of the colon (HP:0100273) | 2.29260942 |
| 36 | Rectovaginal fistula (HP:0000143) | 2.28152557 |
| 37 | Rectal fistula (HP:0100590) | 2.28152557 |
| 38 | Renal hypoplasia (HP:0000089) | 2.25958813 |
| 39 | Acute encephalopathy (HP:0006846) | 2.25046505 |
| 40 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.25022681 |
| 41 | Abnormal hair whorl (HP:0010721) | 2.24759105 |
| 42 | Pachygyria (HP:0001302) | 2.24738841 |
| 43 | Congenital glaucoma (HP:0001087) | 2.24343141 |
| 44 | Abnormality of the line of Schwalbe (HP:0008048) | 2.22813522 |
| 45 | Genital tract atresia (HP:0001827) | 2.19894872 |
| 46 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.19320821 |
| 47 | Ulnar claw (HP:0001178) | 2.18855361 |
| 48 | Inability to walk (HP:0002540) | 2.18699299 |
| 49 | Atonic seizures (HP:0010819) | 2.16915379 |
| 50 | Maternal diabetes (HP:0009800) | 2.15977927 |
| 51 | Neoplasm of the respiratory system (HP:0100606) | 2.15226500 |
| 52 | Preaxial hand polydactyly (HP:0001177) | 2.09887247 |
| 53 | Posterior embryotoxon (HP:0000627) | 2.09253011 |
| 54 | Aplasia/Hypoplasia affecting the fundus (HP:0008057) | 2.09245443 |
| 55 | Gait imbalance (HP:0002141) | 2.08563587 |
| 56 | Mitochondrial inheritance (HP:0001427) | 2.08104021 |
| 57 | Retinal dysplasia (HP:0007973) | 2.04440801 |
| 58 | Nephronophthisis (HP:0000090) | 2.02915028 |
| 59 | Drooling (HP:0002307) | 2.02756941 |
| 60 | Increased corneal curvature (HP:0100692) | 2.02745088 |
| 61 | Keratoconus (HP:0000563) | 2.02745088 |
| 62 | Megalencephaly (HP:0001355) | 2.02313653 |
| 63 | Median cleft lip (HP:0000161) | 2.01914607 |
| 64 | Reticulocytopenia (HP:0001896) | 2.01804583 |
| 65 | Fat malabsorption (HP:0002630) | 2.00600831 |
| 66 | Congenital primary aphakia (HP:0007707) | 2.00286685 |
| 67 | Neoplasm of the adrenal cortex (HP:0100641) | 11.8131211 |
| 68 | Abnormality of the pupil (HP:0000615) | 1.97483139 |
| 69 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.97422059 |
| 70 | Gaze-evoked nystagmus (HP:0000640) | 1.97096197 |
| 71 | Amblyopia (HP:0000646) | 1.94243359 |
| 72 | Postaxial foot polydactyly (HP:0001830) | 1.92086435 |
| 73 | Decreased central vision (HP:0007663) | 1.90813937 |
| 74 | Cerebral hypomyelination (HP:0006808) | 1.90244654 |
| 75 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.90049849 |
| 76 | Freckling (HP:0001480) | 1.89569459 |
| 77 | Absence seizures (HP:0002121) | 1.86159170 |
| 78 | Excessive salivation (HP:0003781) | 1.86125772 |
| 79 | True hermaphroditism (HP:0010459) | 1.85983595 |
| 80 | Scotoma (HP:0000575) | 1.83295887 |
| 81 | Pancreatic cysts (HP:0001737) | 1.82754352 |
| 82 | Partial duplication of thumb phalanx (HP:0009944) | 1.82049414 |
| 83 | Vaginal fistula (HP:0004320) | 1.81444354 |
| 84 | Sclerocornea (HP:0000647) | 1.80806159 |
| 85 | White forelock (HP:0002211) | 1.79681969 |
| 86 | Increased CSF lactate (HP:0002490) | 1.79539576 |
| 87 | Prominent supraorbital ridges (HP:0000336) | 1.77768252 |
| 88 | Poor coordination (HP:0002370) | 1.76854014 |
| 89 | Adrenal hypoplasia (HP:0000835) | 1.76836714 |
| 90 | Hyperglycinemia (HP:0002154) | 1.75583144 |
| 91 | Syncope (HP:0001279) | 1.74430803 |
| 92 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.73702074 |
| 93 | Short tibia (HP:0005736) | 1.73424669 |
| 94 | Generalized tonic-clonic seizures (HP:0002069) | 1.72652175 |
| 95 | Nephrogenic diabetes insipidus (HP:0009806) | 1.71678773 |
| 96 | Patchy hypopigmentation of hair (HP:0011365) | 1.71088329 |
| 97 | Birth length less than 3rd percentile (HP:0003561) | 1.70809092 |
| 98 | Abnormality of lateral ventricle (HP:0030047) | 1.69874842 |
| 99 | Abnormality of the nasal septum (HP:0000419) | 1.69482340 |
| 100 | Intestinal fistula (HP:0100819) | 1.69298352 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TYRO3 | 4.48742581 |
| 2 | TRIM28 | 4.38288755 |
| 3 | DAPK3 | 4.24260417 |
| 4 | FRK | 3.87659497 |
| 5 | MARK1 | 3.40422737 |
| 6 | PIM1 | 2.62393773 |
| 7 | EPHA4 | 2.44854850 |
| 8 | ERBB3 | 2.38513563 |
| 9 | BMPR1B | 2.18558290 |
| 10 | BCR | 2.10470925 |
| 11 | MAP4K2 | 2.05421880 |
| 12 | CASK | 1.95973044 |
| 13 | CDK19 | 1.85057983 |
| 14 | DYRK2 | 1.76113472 |
| 15 | ACVR1B | 1.71610579 |
| 16 | PINK1 | 1.64034570 |
| 17 | WEE1 | 1.62243031 |
| 18 | CSNK1G1 | 1.57750578 |
| 19 | STK39 | 1.56951927 |
| 20 | FGFR2 | 1.48973819 |
| 21 | BMPR2 | 1.44819108 |
| 22 | RPS6KB1 | 1.43642707 |
| 23 | CSNK1D | 1.33091077 |
| 24 | GRK1 | 1.30871020 |
| 25 | PLK2 | 1.30518491 |
| 26 | CSNK1G2 | 1.29512449 |
| 27 | PLK4 | 1.29225146 |
| 28 | WNK4 | 1.23936726 |
| 29 | PRKCZ | 1.14826839 |
| 30 | ADRBK1 | 1.13547882 |
| 31 | WNK3 | 1.10338174 |
| 32 | AKT2 | 1.07262234 |
| 33 | CSNK1G3 | 1.06806594 |
| 34 | PLK1 | 1.05036235 |
| 35 | TGFBR2 | 1.02682964 |
| 36 | ADRBK2 | 1.02235718 |
| 37 | NUAK1 | 0.99760406 |
| 38 | MAPKAPK2 | 0.97905657 |
| 39 | MAPK13 | 0.97693350 |
| 40 | OXSR1 | 0.93795670 |
| 41 | PAK3 | 0.87251645 |
| 42 | CAMK1D | 0.86097107 |
| 43 | CAMKK2 | 0.85245060 |
| 44 | DAPK2 | 0.83660956 |
| 45 | MAP2K7 | 0.81473752 |
| 46 | CAMK4 | 0.74707767 |
| 47 | CSNK1A1L | 0.73652912 |
| 48 | TIE1 | 0.73537824 |
| 49 | GRK5 | 0.71797348 |
| 50 | MAP3K4 | 0.71620349 |
| 51 | ATR | 0.71165232 |
| 52 | FES | 0.68496590 |
| 53 | ABL1 | 0.67697406 |
| 54 | ATM | 0.64273989 |
| 55 | CSNK1A1 | 0.63831415 |
| 56 | SGK223 | 0.62485046 |
| 57 | SGK494 | 0.62485046 |
| 58 | CDC7 | 0.61434895 |
| 59 | PRKCD | 0.60681562 |
| 60 | STK38L | 0.60107344 |
| 61 | PIK3CA | 0.58024822 |
| 62 | PRKDC | 0.57354732 |
| 63 | SGK2 | 0.56508164 |
| 64 | ZAK | 0.56312515 |
| 65 | VRK2 | 0.55992744 |
| 66 | PRKCG | 0.55954047 |
| 67 | MINK1 | 0.54978851 |
| 68 | PRKCE | 0.54633683 |
| 69 | DYRK3 | 0.54053876 |
| 70 | CHUK | 0.53268357 |
| 71 | EIF2AK3 | 0.53110517 |
| 72 | ILK | 0.51974545 |
| 73 | CLK1 | 0.51573803 |
| 74 | STK11 | 0.51407348 |
| 75 | KDR | 0.51134880 |
| 76 | LRRK2 | 0.51056388 |
| 77 | CDK5 | 0.50777235 |
| 78 | CAMK1G | 0.49504277 |
| 79 | PRKACA | 0.49503933 |
| 80 | NTRK2 | 0.49013403 |
| 81 | YES1 | 0.48141035 |
| 82 | CAMK1 | 0.47013924 |
| 83 | STK3 | 0.46185567 |
| 84 | STK38 | 0.44751859 |
| 85 | GSK3B | 0.44072533 |
| 86 | CHEK2 | 0.43781691 |
| 87 | AKT1 | 0.43380453 |
| 88 | DYRK1A | 0.42944595 |
| 89 | SIK2 | 0.39737979 |
| 90 | CAMK2A | 0.39343727 |
| 91 | MKNK2 | 0.39061689 |
| 92 | PRKCB | 0.38989877 |
| 93 | RPS6KA3 | 0.37976901 |
| 94 | MARK2 | 0.37826953 |
| 95 | FER | 0.35697655 |
| 96 | PRKCI | 0.35072624 |
| 97 | CDK2 | 0.34794712 |
| 98 | PRKAA1 | 0.34676300 |
| 99 | TEC | 0.34222122 |
| 100 | PRKACG | 0.34050851 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 3.18904200 |
| 2 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.77459775 |
| 3 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.70259659 |
| 4 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.63183191 |
| 5 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.60537284 |
| 6 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.46551982 |
| 7 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.27403665 |
| 8 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 2.21667747 |
| 9 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.18297974 |
| 10 | p53 signaling pathway_Homo sapiens_hsa04115 | 2.08932043 |
| 11 | Phototransduction_Homo sapiens_hsa04744 | 1.99855917 |
| 12 | Protein export_Homo sapiens_hsa03060 | 1.98335758 |
| 13 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.97439321 |
| 14 | Bladder cancer_Homo sapiens_hsa05219 | 1.91495960 |
| 15 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.85450777 |
| 16 | Nicotine addiction_Homo sapiens_hsa05033 | 1.83020653 |
| 17 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.72165634 |
| 18 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.71906947 |
| 19 | Melanoma_Homo sapiens_hsa05218 | 1.64100300 |
| 20 | Taste transduction_Homo sapiens_hsa04742 | 1.57425194 |
| 21 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.54515039 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.49851997 |
| 23 | Parkinsons disease_Homo sapiens_hsa05012 | 1.47099205 |
| 24 | Basal transcription factors_Homo sapiens_hsa03022 | 1.46857874 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.42852065 |
| 26 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.41481686 |
| 27 | Glioma_Homo sapiens_hsa05214 | 1.39666806 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.38198678 |
| 29 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.37825819 |
| 30 | RNA polymerase_Homo sapiens_hsa03020 | 1.33690182 |
| 31 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.31746840 |
| 32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.30253956 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.27603909 |
| 34 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.23647791 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.23099062 |
| 36 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.21690030 |
| 37 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.21148786 |
| 38 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.14485094 |
| 39 | Alzheimers disease_Homo sapiens_hsa05010 | 1.14478659 |
| 40 | Morphine addiction_Homo sapiens_hsa05032 | 1.12493313 |
| 41 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.12201246 |
| 42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.11010891 |
| 43 | Axon guidance_Homo sapiens_hsa04360 | 1.05439727 |
| 44 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.04403257 |
| 45 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.03312563 |
| 46 | Huntingtons disease_Homo sapiens_hsa05016 | 1.03100364 |
| 47 | Histidine metabolism_Homo sapiens_hsa00340 | 1.01190484 |
| 48 | Ribosome_Homo sapiens_hsa03010 | 0.96097108 |
| 49 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.93314282 |
| 50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.90356239 |
| 51 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.90297954 |
| 52 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.90196598 |
| 53 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.89930502 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.87853565 |
| 55 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.87603547 |
| 56 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.87167718 |
| 57 | Long-term depression_Homo sapiens_hsa04730 | 0.85295903 |
| 58 | RNA transport_Homo sapiens_hsa03013 | 0.84530877 |
| 59 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83073451 |
| 60 | Prostate cancer_Homo sapiens_hsa05215 | 0.80809921 |
| 61 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.76756256 |
| 62 | Salivary secretion_Homo sapiens_hsa04970 | 0.76098300 |
| 63 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.73356413 |
| 64 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.73054695 |
| 65 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.70008013 |
| 66 | Retinol metabolism_Homo sapiens_hsa00830 | 0.69850448 |
| 67 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.68491816 |
| 68 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.67538351 |
| 69 | GABAergic synapse_Homo sapiens_hsa04727 | 0.65962007 |
| 70 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.65182525 |
| 71 | Insulin secretion_Homo sapiens_hsa04911 | 0.65038841 |
| 72 | Cell cycle_Homo sapiens_hsa04110 | 0.63122013 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.62983227 |
| 74 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.61762051 |
| 75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.61441981 |
| 76 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.58727432 |
| 77 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57902529 |
| 78 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.55309036 |
| 79 | Melanogenesis_Homo sapiens_hsa04916 | 0.54491952 |
| 80 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.53783953 |
| 81 | Circadian entrainment_Homo sapiens_hsa04713 | 0.53029522 |
| 82 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.52704538 |
| 83 | Cocaine addiction_Homo sapiens_hsa05030 | 0.52461893 |
| 84 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.50848182 |
| 85 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.50556870 |
| 86 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.49144310 |
| 87 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.48237357 |
| 88 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.47904089 |
| 89 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.47853226 |
| 90 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.44373270 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.41439779 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.40236206 |
| 93 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38574542 |
| 94 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.38261432 |
| 95 | Long-term potentiation_Homo sapiens_hsa04720 | 0.38049716 |
| 96 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.35552790 |
| 97 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.35519779 |
| 98 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.35458182 |
| 99 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.33161743 |
| 100 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30109374 |

