RPL32

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L32E family of ribosomal proteins. It is located in the cytoplasm. Although some studies have mapped this gene to 3q13.3-q21, it is believed to map to 3p25-p24. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants encoding the same protein have been observed for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)9.42016643
2* viral transcription (GO:0019083)9.07031288
3* translational termination (GO:0006415)8.71461934
4ribosomal small subunit biogenesis (GO:0042274)8.18599801
5* translational elongation (GO:0006414)7.48025672
6* SRP-dependent cotranslational protein targeting to membrane (GO:0006614)7.44458859
7* cotranslational protein targeting to membrane (GO:0006613)7.29355653
8* protein targeting to ER (GO:0045047)7.27973985
9maturation of SSU-rRNA (GO:0030490)7.12282224
10* establishment of protein localization to endoplasmic reticulum (GO:0072599)6.95485076
11* nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)6.85256777
12* protein localization to endoplasmic reticulum (GO:0070972)6.81687602
13* viral life cycle (GO:0019058)6.75826773
14* cellular protein complex disassembly (GO:0043624)6.75060887
15* translational initiation (GO:0006413)6.48613882
16* protein complex disassembly (GO:0043241)5.95273255
17ribosomal large subunit biogenesis (GO:0042273)5.93988915
18* macromolecular complex disassembly (GO:0032984)5.55182227
19ATP synthesis coupled proton transport (GO:0015986)5.53561086
20energy coupled proton transport, down electrochemical gradient (GO:0015985)5.53561086
21* nuclear-transcribed mRNA catabolic process (GO:0000956)4.99225910
22* protein targeting to membrane (GO:0006612)4.81577366
23* mRNA catabolic process (GO:0006402)4.74267213
24ribonucleoprotein complex biogenesis (GO:0022613)4.62353720
25* translation (GO:0006412)4.60196675
26* RNA catabolic process (GO:0006401)4.44789940
27formation of translation preinitiation complex (GO:0001731)4.32413553
28DNA deamination (GO:0045006)4.31704527
29chaperone-mediated protein transport (GO:0072321)4.17240528
30respiratory electron transport chain (GO:0022904)3.89599382
31DNA strand elongation involved in DNA replication (GO:0006271)3.86465109
32electron transport chain (GO:0022900)3.79150000
33telomere maintenance via semi-conservative replication (GO:0032201)3.78862048
34establishment of protein localization to mitochondrial membrane (GO:0090151)3.73715912
35rRNA processing (GO:0006364)3.73363635
36DNA strand elongation (GO:0022616)3.67680333
37rRNA metabolic process (GO:0016072)3.59944330
38mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.55055978
39DNA unwinding involved in DNA replication (GO:0006268)3.52260453
40cellular component biogenesis (GO:0044085)3.41277971
41telomere maintenance via recombination (GO:0000722)3.32304115
42DNA replication initiation (GO:0006270)3.28622695
43* establishment of protein localization to membrane (GO:0090150)3.21892845
44* protein localization to organelle (GO:0033365)3.15825519
45pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.13009603
46mitotic recombination (GO:0006312)3.11527264
47establishment of integrated proviral latency (GO:0075713)3.05784422
48regulation of mitochondrial translation (GO:0070129)3.05644401
49negative regulation of RNA splicing (GO:0033119)3.02433816
50ATP biosynthetic process (GO:0006754)3.01084753
51* establishment of protein localization to organelle (GO:0072594)2.99330211
52protein targeting to mitochondrion (GO:0006626)2.98926097
53telomere maintenance via telomere lengthening (GO:0010833)2.98886188
54nucleotide-excision repair, DNA gap filling (GO:0006297)2.96668392
55regulation of translational fidelity (GO:0006450)2.95435084
56* protein targeting (GO:0006605)2.93658858
57mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.92891427
58mitochondrial respiratory chain complex I assembly (GO:0032981)2.92891427
59NADH dehydrogenase complex assembly (GO:0010257)2.92891427
60oxidative phosphorylation (GO:0006119)2.92207399
61spliceosomal snRNP assembly (GO:0000387)2.91801773
62mitochondrial respiratory chain complex assembly (GO:0033108)2.88391258
63protein complex biogenesis (GO:0070271)2.86543835
64purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.83845723
65purine nucleoside triphosphate biosynthetic process (GO:0009145)2.82521763
66ncRNA 3-end processing (GO:0043628)2.81632583
67ribonucleoside triphosphate biosynthetic process (GO:0009201)2.80316952
68ribosome biogenesis (GO:0042254)2.79173528
69spliceosomal complex assembly (GO:0000245)2.78657647
70establishment of protein localization to mitochondrion (GO:0072655)2.77563779
71pseudouridine synthesis (GO:0001522)2.77484345
72inner mitochondrial membrane organization (GO:0007007)2.75376842
73protein localization to kinetochore (GO:0034501)2.72897048
74pyrimidine nucleotide catabolic process (GO:0006244)2.71564295
75negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.68534379
76exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.68351009
77CENP-A containing nucleosome assembly (GO:0034080)2.68313377
78nucleobase biosynthetic process (GO:0046112)2.67250441
79chromatin remodeling at centromere (GO:0031055)2.65775492
80transcription-coupled nucleotide-excision repair (GO:0006283)2.62658291
81deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.62573511
82protein localization to mitochondrion (GO:0070585)2.60586659
83DNA replication checkpoint (GO:0000076)2.60251310
84ncRNA processing (GO:0034470)2.60119331
85nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.57731935
86histone mRNA metabolic process (GO:0008334)2.57407363
87ribonucleoprotein complex subunit organization (GO:0071826)2.56298168
88folic acid-containing compound biosynthetic process (GO:0009396)2.54675178
89DNA replication-dependent nucleosome assembly (GO:0006335)2.54178429
90DNA replication-dependent nucleosome organization (GO:0034723)2.54178429
91purine nucleoside monophosphate biosynthetic process (GO:0009127)2.53902769
92purine ribonucleoside monophosphate biosynthetic process (GO:0009168)2.53902769
93* gene expression (GO:0010467)2.53826899
94proteasome assembly (GO:0043248)2.52426851
95kinetochore organization (GO:0051383)2.52080486
96termination of RNA polymerase III transcription (GO:0006386)2.50801946
97transcription elongation from RNA polymerase III promoter (GO:0006385)2.50801946
98DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.50687766
99termination of RNA polymerase II transcription (GO:0006369)2.49912101
100regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.49251913
101negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.48934813
102negative regulation of ligase activity (GO:0051352)2.48934813
103antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.48301983
104positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.48291589
105DNA replication-independent nucleosome assembly (GO:0006336)2.48287444
106DNA replication-independent nucleosome organization (GO:0034724)2.48287444
107ribonucleoprotein complex assembly (GO:0022618)2.48141069
108mRNA splicing, via spliceosome (GO:0000398)2.48039313
109RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.48039313
110RNA splicing, via transesterification reactions (GO:0000375)2.47806680
111heterochromatin organization (GO:0070828)2.47335645
112mitotic nuclear envelope disassembly (GO:0007077)2.47301061
113intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.47300755
114signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.47300755
115nucleobase-containing small molecule interconversion (GO:0015949)2.47104191
116guanosine-containing compound biosynthetic process (GO:1901070)2.46817373
117IMP biosynthetic process (GO:0006188)2.46800254
118anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.46778637
119* cellular component disassembly (GO:0022411)2.46446640
120UTP biosynthetic process (GO:0006228)2.44294133
121establishment of viral latency (GO:0019043)2.44211040
122rRNA modification (GO:0000154)2.44123981
123signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.43590487
124signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.43590487
125signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.43590487
126aerobic respiration (GO:0009060)2.43463319
127viral mRNA export from host cell nucleus (GO:0046784)2.42968408
128ribosome assembly (GO:0042255)2.41872921
129signal transduction involved in DNA integrity checkpoint (GO:0072401)2.41610703
130signal transduction involved in DNA damage checkpoint (GO:0072422)2.41610703
131pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.41520435
132mitochondrial transport (GO:0006839)2.40662226
133ncRNA metabolic process (GO:0034660)2.40487107
134* protein localization to membrane (GO:0072657)2.39883089
135protein localization to chromosome, centromeric region (GO:0071459)2.39407085
136mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.38945136
137regulation of protein heterodimerization activity (GO:0043497)2.38928181
138nucleoside triphosphate biosynthetic process (GO:0009142)2.38926468
139pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.37951362
140myeloid cell homeostasis (GO:0002262)2.37386282
141pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.36473817
142pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.36300981
143positive regulation of viral transcription (GO:0050434)2.33852378
144ribonucleoside monophosphate biosynthetic process (GO:0009156)2.32335037

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.86549548
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.52655556
3* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.96765649
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.70072495
5* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.26338112
6* EST1_17652178_ChIP-ChIP_JURKAT_Human3.08345973
7E2F4_17652178_ChIP-ChIP_JURKAT_Human3.01108086
8* GABP_17652178_ChIP-ChIP_JURKAT_Human2.97213954
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.85295726
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.81236591
11* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.77580044
12KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.73867695
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.69471399
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.66406503
15* XRN2_22483619_ChIP-Seq_HELA_Human2.60827875
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.59626683
17JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.49346056
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.48715598
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.40808629
20* CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.33006500
21* VDR_23849224_ChIP-Seq_CD4+_Human2.29970505
22* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.23700896
23* ELF1_17652178_ChIP-ChIP_JURKAT_Human2.18204692
24TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.17171508
25NELFA_20434984_ChIP-Seq_ESCs_Mouse2.14665986
26* TTF2_22483619_ChIP-Seq_HELA_Human2.08365734
27NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.02824763
28* FOXP3_21729870_ChIP-Seq_TREG_Human2.01490302
29DCP1A_22483619_ChIP-Seq_HELA_Human1.96435308
30* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.90572585
31* ELK1_19687146_ChIP-ChIP_HELA_Human1.90250326
32MYC_22102868_ChIP-Seq_BL_Human1.87304843
33* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.82785636
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.77303984
35TP63_17297297_ChIP-ChIP_HaCaT_Human1.74373767
36FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.72133376
37SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.70532611
38CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.69543107
39* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.68621100
40EGR1_19374776_ChIP-ChIP_THP-1_Human1.62928112
41GABP_19822575_ChIP-Seq_HepG2_Human1.62217677
42CIITA_25753668_ChIP-Seq_RAJI_Human1.60998906
43VDR_21846776_ChIP-Seq_THP-1_Human1.56355308
44PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.56270046
45ERG_20887958_ChIP-Seq_HPC-7_Mouse1.55857537
46E2F1_21310950_ChIP-Seq_MCF-7_Human1.53840390
47FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.51818012
48IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.50526609
49POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.50214621
50THAP11_20581084_ChIP-Seq_MESCs_Mouse1.49567448
51FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.48481507
52ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.47038478
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.46815926
54NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39211896
55* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.38946028
56MYCN_18555785_ChIP-Seq_MESCs_Mouse1.37433292
57ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.37312190
58SPI1_23547873_ChIP-Seq_NB4_Human1.35679139
59YY1_21170310_ChIP-Seq_MESCs_Mouse1.34927844
60MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.34211951
61AR_21909140_ChIP-Seq_LNCAP_Human1.30966673
62NOTCH1_21737748_ChIP-Seq_TLL_Human1.29733904
63SRF_21415370_ChIP-Seq_HL-1_Mouse1.28650634
64CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.27232227
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21725589
66KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.21588873
67YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.21301339
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.20837692
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.19773973
70ZNF263_19887448_ChIP-Seq_K562_Human1.19472254
71KDM5A_27292631_Chip-Seq_BREAST_Human1.19184208
72PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.18279840
73SCL_19346495_ChIP-Seq_HPC-7_Human1.16819948
74MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.16587350
75* ELK1_22589737_ChIP-Seq_MCF10A_Human1.16424844
76* CTCF_18555785_ChIP-Seq_MESCs_Mouse1.14964908
77HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.13589350
78SRY_22984422_ChIP-ChIP_TESTIS_Rat1.12915700
79STAT3_1855785_ChIP-Seq_MESCs_Mouse1.12688317
80ESR1_15608294_ChIP-ChIP_MCF-7_Human1.12029021
81RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.10269449
82TP63_19390658_ChIP-ChIP_HaCaT_Human1.09759927
83MYC_18940864_ChIP-ChIP_HL60_Human1.08084044
84IRF8_22096565_ChIP-ChIP_GC-B_Human1.07968233
85STAT4_19710469_ChIP-ChIP_TH1__Mouse1.07914045
86E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.07750173
87CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.06603980
88RBPJ_22232070_ChIP-Seq_NCS_Mouse1.06532603
89* TET1_21451524_ChIP-Seq_MESCs_Mouse1.06471895
90POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.05775461
91MAF_26560356_Chip-Seq_TH2_Human1.05255305
92GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04987708
93OCT4_18692474_ChIP-Seq_MEFs_Mouse1.01814899
94* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01130336
95FOXP1_21924763_ChIP-Seq_HESCs_Human1.00613008
96HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.98245096
97TFEB_21752829_ChIP-Seq_HELA_Human0.97760579
98KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.97100913
99UTX_26944678_Chip-Seq_JUKART_Human0.96206206
100SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.95829922
101MYB_26560356_Chip-Seq_TH2_Human0.95581522
102KLF4_18555785_ChIP-Seq_MESCs_Mouse0.95571168
103MAF_26560356_Chip-Seq_TH1_Human0.95253699
104DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.94563057
105CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.93377783
106BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92284712
107SOX2_18555785_ChIP-Seq_MESCs_Mouse0.92039260
108ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.91877385
109SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.91797113
110MYB_21317192_ChIP-Seq_ERMYB_Mouse0.91782111
111MYCN_21190229_ChIP-Seq_SHEP-21N_Human0.91428980
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91193222
113CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.91061895
114* CTCF_26484167_Chip-Seq_Bcells_Mouse0.90898240
115E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.89375379
116PADI4_21655091_ChIP-ChIP_MCF-7_Human0.89015156
117SOX2_18692474_ChIP-Seq_MEFs_Mouse0.87403240
118* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84571253

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.27648740
2MP0003693_abnormal_embryo_hatching4.05182303
3MP0004957_abnormal_blastocyst_morpholog3.41551332
4MP0010094_abnormal_chromosome_stability3.14214870
5MP0003077_abnormal_cell_cycle2.93385408
6MP0002396_abnormal_hematopoietic_system2.86880930
7MP0003111_abnormal_nucleus_morphology2.79028389
8MP0006292_abnormal_olfactory_placode2.72783954
9MP0008057_abnormal_DNA_replication2.63212799
10MP0003763_abnormal_thymus_physiology2.34220953
11MP0008007_abnormal_cellular_replicative2.18058674
12MP0008058_abnormal_DNA_repair2.12567850
13MP0000490_abnormal_crypts_of2.09650800
14MP0003806_abnormal_nucleotide_metabolis2.07422990
15MP0004808_abnormal_hematopoietic_stem1.98065897
16MP0001835_abnormal_antigen_presentation1.89994344
17MP0009333_abnormal_splenocyte_physiolog1.89026555
18MP0010352_gastrointestinal_tract_polyps1.85917294
19MP0005174_abnormal_tail_pigmentation1.81995732
20MP0003786_premature_aging1.79991270
21MP0008932_abnormal_embryonic_tissue1.78924153
22MP0002398_abnormal_bone_marrow1.70090572
23MP0002166_altered_tumor_susceptibility1.69678174
24MP0000685_abnormal_immune_system1.65872778
25MP0005671_abnormal_response_to1.57629193
26MP0001545_abnormal_hematopoietic_system1.55146390
27MP0005397_hematopoietic_system_phenotyp1.55146390
28MP0001800_abnormal_humoral_immune1.54677794
29MP0006054_spinal_hemorrhage1.54409664
30MP0002722_abnormal_immune_system1.53559697
31MP0000703_abnormal_thymus_morphology1.53482387
32MP0000350_abnormal_cell_proliferation1.52327041
33MP0001346_abnormal_lacrimal_gland1.51923471
34MP0003136_yellow_coat_color1.48095816
35MP0000566_synostosis1.47070799
36MP0002006_tumorigenesis1.43034265
37MP0000689_abnormal_spleen_morphology1.42613367
38MP0002160_abnormal_reproductive_system1.42429355
39MP0002019_abnormal_tumor_incidence1.41003837
40MP0009785_altered_susceptibility_to1.40190485
41MP0002420_abnormal_adaptive_immunity1.39152742
42MP0001730_embryonic_growth_arrest1.36829091
43MP0001819_abnormal_immune_cell1.36374670
44MP0002452_abnormal_antigen_presenting1.34609191
45MP0006036_abnormal_mitochondrial_physio1.33668154
46MP0002095_abnormal_skin_pigmentation1.33455904
47MP0000716_abnormal_immune_system1.32854966
48MP0002429_abnormal_blood_cell1.32745503
49MP0004185_abnormal_adipocyte_glucose1.32716382
50MP0002132_abnormal_respiratory_system1.31103627
51MP0000465_gastrointestinal_hemorrhage1.31009006
52MP0005075_abnormal_melanosome_morpholog1.30198837
53MP0000858_altered_metastatic_potential1.28445263
54MP0001853_heart_inflammation1.27818174
55MP0002723_abnormal_immune_serum1.26133919
56MP0002405_respiratory_system_inflammati1.25523548
57MP0005025_abnormal_response_to1.24908664
58MP0003567_abnormal_fetal_cardiomyocyte1.24074444
59MP0001873_stomach_inflammation1.23699643
60MP0010155_abnormal_intestine_physiology1.23321040
61MP0003436_decreased_susceptibility_to1.23018793
62MP0000678_abnormal_parathyroid_gland1.22206301
63MP0005000_abnormal_immune_tolerance1.21870612
64MP0002249_abnormal_larynx_morphology1.21217268
65MP0000313_abnormal_cell_death1.20796943
66MP0002148_abnormal_hypersensitivity_rea1.20224577
67MP0003123_paternal_imprinting1.17109195
68MP0010307_abnormal_tumor_latency1.17087754
69MP0000049_abnormal_middle_ear1.13756949
70MP0003941_abnormal_skin_development1.13428167
71MP0003315_abnormal_perineum_morphology1.10885359
72MP0002277_abnormal_respiratory_mucosa1.09691616
73MP0002938_white_spotting1.06303051
74MP0002080_prenatal_lethality1.03811199
75MP0001697_abnormal_embryo_size1.02152895
76MP0001286_abnormal_eye_development0.99866983
77MP0004381_abnormal_hair_follicle0.99856095
78MP0002653_abnormal_ependyma_morphology0.99495941
79MP0005501_abnormal_skin_physiology0.99300125
80MP0002210_abnormal_sex_determination0.98620497
81MP0003938_abnormal_ear_development0.98238250
82MP0003866_abnormal_defecation0.98073249
83MP0002697_abnormal_eye_size0.97225041
84MP0005464_abnormal_platelet_physiology0.96998853
85MP0001790_abnormal_immune_system0.95251397
86MP0005387_immune_system_phenotype0.95251397
87MP0001881_abnormal_mammary_gland0.95212975
88MP0006035_abnormal_mitochondrial_morpho0.92997706
89MP0002638_abnormal_pupillary_reflex0.92584793
90MP0009278_abnormal_bone_marrow0.92143897
91MP0005023_abnormal_wound_healing0.91349118
92MP0008995_early_reproductive_senescence0.90024954
93MP0000750_abnormal_muscle_regeneration0.89734665
94MP0005389_reproductive_system_phenotype0.89675871
95MP0005380_embryogenesis_phenotype0.89429747
96MP0001672_abnormal_embryogenesis/_devel0.89429747
97MP0002086_abnormal_extraembryonic_tissu0.85068788
98MP0009250_abnormal_appendicular_skeleto0.82509876
99MP0002085_abnormal_embryonic_tissue0.82353580
100MP0005379_endocrine/exocrine_gland_phen0.82057323
101MP0004197_abnormal_fetal_growth/weight/0.81682152
102MP0003186_abnormal_redox_activity0.81404902
103MP0000372_irregular_coat_pigmentation0.81280976
104MP0003984_embryonic_growth_retardation0.80886098
105MP0002088_abnormal_embryonic_growth/wei0.80336588
106MP0004947_skin_inflammation0.79464421
107MP0001216_abnormal_epidermal_layer0.78527492
108MP0000477_abnormal_intestine_morphology0.78436303
109MP0001145_abnormal_male_reproductive0.78279502
110MP0001919_abnormal_reproductive_system0.77379642
111MP0002009_preneoplasia0.77077259
112MP0001293_anophthalmia0.77029630
113MP0002084_abnormal_developmental_patter0.76880296
114MP0003724_increased_susceptibility_to0.76556023
115MP0009053_abnormal_anal_canal0.76045571
116MP0002796_impaired_skin_barrier0.75834752
117MP0003718_maternal_effect0.75506755
118MP0003942_abnormal_urinary_system0.74823004
119MP0001845_abnormal_inflammatory_respons0.74673077
120MP0000537_abnormal_urethra_morphology0.74360054
121MP0002419_abnormal_innate_immunity0.73317572
122MP0002932_abnormal_joint_morphology0.69328099
123MP0003448_altered_tumor_morphology0.69061078
124MP0002111_abnormal_tail_morphology0.68957712
125MP0002092_abnormal_eye_morphology0.68577069
126MP0002060_abnormal_skin_morphology0.68506207
127MP0000762_abnormal_tongue_morphology0.68235350
128MP0010030_abnormal_orbit_morphology0.67870265
129MP0002163_abnormal_gland_morphology0.66874586
130MP0000358_abnormal_cell_content/0.66748979
131MP0008789_abnormal_olfactory_epithelium0.66456372
132MP0003959_abnormal_lean_body0.65617115
133MP0005408_hypopigmentation0.65160109
134MP0009931_abnormal_skin_appearance0.64732441
135MP0002098_abnormal_vibrissa_morphology0.63455168
136MP0000631_abnormal_neuroendocrine_gland0.63097603
137MP0000653_abnormal_sex_gland0.61537064
138MP0001340_abnormal_eyelid_morphology0.61201483
139MP0001348_abnormal_lacrimal_gland0.60243959
140MP0009697_abnormal_copulation0.59421113
141MP0003937_abnormal_limbs/digits/tail_de0.57239308
142MP0001929_abnormal_gametogenesis0.57046407
143MP0003936_abnormal_reproductive_system0.55281373

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)8.71155475
2Reticulocytopenia (HP:0001896)8.18067015
3Abnormal number of erythroid precursors (HP:0012131)7.89030196
4Macrocytic anemia (HP:0001972)5.65121631
5Pallor (HP:0000980)5.46221749
6Thrombocytosis (HP:0001894)4.22642611
7Acute necrotizing encephalopathy (HP:0006965)4.16739486
8Abnormal mitochondria in muscle tissue (HP:0008316)4.07840525
9Aplastic anemia (HP:0001915)3.83117772
10Increased intramyocellular lipid droplets (HP:0012240)3.82336734
11Colon cancer (HP:0003003)3.81984497
1211 pairs of ribs (HP:0000878)3.60636385
13Acute encephalopathy (HP:0006846)3.55477954
14Renal Fanconi syndrome (HP:0001994)3.40531391
15Increased muscle lipid content (HP:0009058)3.40406945
16Increased CSF lactate (HP:0002490)3.36132574
17Aplasia/Hypoplasia of the sacrum (HP:0008517)3.33424296
18Progressive macrocephaly (HP:0004481)3.23921569
19IgM deficiency (HP:0002850)3.12057861
20Oral leukoplakia (HP:0002745)2.97776227
21Absent thumb (HP:0009777)2.93779906
22Abnormality of the parietal bone (HP:0002696)2.91680417
23Hepatic necrosis (HP:0002605)2.87868587
24Abnormality of reticulocytes (HP:0004312)2.75289266
25Cerebral edema (HP:0002181)2.69612905
26Abnormal hemoglobin (HP:0011902)2.62173521
27Depressed nasal ridge (HP:0000457)2.54144349
28Exercise intolerance (HP:0003546)2.49548225
29Elevated erythrocyte sedimentation rate (HP:0003565)2.46396755
30Myelodysplasia (HP:0002863)2.45090583
31Selective tooth agenesis (HP:0001592)2.44197335
32Birth length less than 3rd percentile (HP:0003561)2.42883391
33Multiple enchondromatosis (HP:0005701)2.39152612
34Trismus (HP:0000211)2.35029793
35Progressive muscle weakness (HP:0003323)2.34578101
36Increased serum lactate (HP:0002151)2.33488893
37Rough bone trabeculation (HP:0100670)2.25619308
38Petechiae (HP:0000967)2.24971775
39Microvesicular hepatic steatosis (HP:0001414)2.23045013
40Lactic acidosis (HP:0003128)2.22442431
41Recurrent bronchitis (HP:0002837)2.21998191
42Increased hepatocellular lipid droplets (HP:0006565)2.21600986
43Congenital, generalized hypertrichosis (HP:0004540)2.20728470
44Decreased activity of mitochondrial respiratory chain (HP:0008972)2.17141436
45Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.17141436
46Stenosis of the external auditory canal (HP:0000402)2.14574140
47Missing ribs (HP:0000921)2.14254474
48Chronic otitis media (HP:0000389)2.14135073
49Poikiloderma (HP:0001029)2.13950212
50Thick lower lip vermilion (HP:0000179)2.12233581
51Exertional dyspnea (HP:0002875)2.12155929
52Duplication of thumb phalanx (HP:0009942)2.11190064
53Premature graying of hair (HP:0002216)2.10431275
54Lymphoma (HP:0002665)2.10084013
55Asplenia (HP:0001746)2.08950807
56Migraine (HP:0002076)2.08417911
57Basal cell carcinoma (HP:0002671)2.07700649
58Carpal bone hypoplasia (HP:0001498)2.07023659
59Seborrheic dermatitis (HP:0001051)2.06671008
60Abnormality of the preputium (HP:0100587)2.05943636
61Abnormality of T cell physiology (HP:0011840)2.04354535
62Triphalangeal thumb (HP:0001199)2.03658248
63Microretrognathia (HP:0000308)2.03616276
64Abnormality of renal resorption (HP:0011038)2.03210370
65Leukodystrophy (HP:0002415)2.02135109
66Abnormality of T cells (HP:0002843)2.00145114
67Chromsome breakage (HP:0040012)1.99265703
68Respiratory failure (HP:0002878)1.99232811
69Breast hypoplasia (HP:0003187)1.98318603
70Hypoplasia of the radius (HP:0002984)1.97196841
71Nasolacrimal duct obstruction (HP:0000579)1.96572011
72Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.96408118
73Panhypogammaglobulinemia (HP:0003139)1.94230621
74Neoplasm of the pancreas (HP:0002894)1.92812787
75Type I transferrin isoform profile (HP:0003642)1.92534615
76Cleft eyelid (HP:0000625)1.92424316
77Aplasia/Hypoplasia of the spleen (HP:0010451)1.92409410
78Abnormal number of incisors (HP:0011064)1.91041515
79Glossoptosis (HP:0000162)1.90452850
80IgG deficiency (HP:0004315)1.89589129
81Pancytopenia (HP:0001876)1.87632871
82Respiratory difficulties (HP:0002880)1.86067386
83Lipid accumulation in hepatocytes (HP:0006561)1.83783302
84Concave nail (HP:0001598)1.83508704
85Hypertensive crisis (HP:0100735)1.82112571
86Hyperthyroidism (HP:0000836)1.81801734
87Patellar aplasia (HP:0006443)1.81756297
88Amaurosis fugax (HP:0100576)1.81178065
89Cellular immunodeficiency (HP:0005374)1.80374506
90Aplasia/Hypoplasia of the thymus (HP:0010515)1.80334887
91Recurrent viral infections (HP:0004429)1.80235225
92Abnormality of chromosome stability (HP:0003220)1.76107538
93Atresia of the external auditory canal (HP:0000413)1.75792982
94Woolly hair (HP:0002224)1.75649551
95Abnormality of B cell number (HP:0010975)1.74982214
96B lymphocytopenia (HP:0010976)1.74982214
97Squamous cell carcinoma (HP:0002860)1.74691978
98Mitochondrial inheritance (HP:0001427)1.74650837
99Sparse eyelashes (HP:0000653)1.74477817
100Medulloblastoma (HP:0002885)1.74421987
101Meckel diverticulum (HP:0002245)1.74317190
102Agnosia (HP:0010524)1.72490889
103Aplasia/Hypoplasia of the patella (HP:0006498)1.71245472
104Partial duplication of thumb phalanx (HP:0009944)1.70007380
105Hepatocellular necrosis (HP:0001404)1.69399088
106Bone marrow hypocellularity (HP:0005528)1.69259686
107Truncus arteriosus (HP:0001660)1.68953230
108Abnormality of the ileum (HP:0001549)1.68076933
109Abnormality of cochlea (HP:0000375)1.67259769
110Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.67004903
111Muscle fiber atrophy (HP:0100295)1.65373242
112Chromosomal breakage induced by crosslinking agents (HP:0003221)1.65175504
113Abnormality of cells of the lymphoid lineage (HP:0012140)1.64550017
114T lymphocytopenia (HP:0005403)1.64346351
115Myositis (HP:0100614)1.64024010
116Broad distal phalanx of finger (HP:0009836)1.64023621
117Acute lymphatic leukemia (HP:0006721)1.63929961
118Hyperphosphaturia (HP:0003109)1.63395244
119Tracheoesophageal fistula (HP:0002575)1.63064997
120Partial duplication of the phalanx of hand (HP:0009999)1.62370005
121Pulmonary fibrosis (HP:0002206)1.60459866
122Horseshoe kidney (HP:0000085)1.59950427
123Abnormal trabecular bone morphology (HP:0100671)1.59899796
124Hypoplasia of the pons (HP:0012110)1.59153862
125Lymphopenia (HP:0001888)1.59125284
1263-Methylglutaconic aciduria (HP:0003535)1.58624104
127Abnormality of DNA repair (HP:0003254)1.57896733
128Degeneration of anterior horn cells (HP:0002398)1.57781416
129Abnormality of the anterior horn cell (HP:0006802)1.57781416
130Prolonged bleeding time (HP:0003010)1.56981620
131Rib fusion (HP:0000902)1.55696800
132Esophageal neoplasm (HP:0100751)1.51594920
133Neoplasm of head and neck (HP:0012288)1.51594920
134Colitis (HP:0002583)1.51378402
135Septo-optic dysplasia (HP:0100842)1.50886134
136Hypoparathyroidism (HP:0000829)1.50721301
137Optic disc pallor (HP:0000543)1.50650881
138Abnormality of the pons (HP:0007361)1.49819048
139Abnormality of small intestinal villus morphology (HP:0011472)1.49701677
140Villous atrophy (HP:0011473)1.49701677
141Short thumb (HP:0009778)1.49517756
142Short middle phalanx of the 5th finger (HP:0004220)1.49309012
143Homocystinuria (HP:0002156)1.48416464
144Abnormality of homocysteine metabolism (HP:0010919)1.48416464
145Abnormal urine phosphate concentration (HP:0012599)1.46631456
146Diastasis recti (HP:0001540)1.46063241
147Supernumerary ribs (HP:0005815)1.45816218
148Renal tubular dysfunction (HP:0000124)1.44573375

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.45763395
2VRK23.84814696
3WEE13.15175952
4BUB13.09257172
5EEF2K2.86495470
6RPS6KB22.70653776
7MAP4K12.45162199
8TLK12.44235843
9CDC72.38513145
10TGFBR12.31437013
11LRRK22.29482117
12STK162.20735421
13SRPK12.18167503
14PASK2.10428218
15PIM22.10196020
16VRK12.05400575
17SMG11.99205157
18EIF2AK11.85931455
19TRIB31.82804187
20NEK21.70303650
21MST41.59895759
22EIF2AK31.57500493
23ACVR1B1.53776454
24DYRK31.53645437
25FLT31.53230943
26BTK1.47568110
27AURKB1.45247127
28TEC1.42679085
29RPS6KA41.42261707
30CDK71.41637728
31PRPF4B1.39792134
32MKNK11.36909128
33TESK21.36194347
34STK101.35432393
35BRSK21.31877854
36PBK1.31865293
37TSSK61.28702981
38KDR1.28341479
39MAP3K101.21738330
40MAPKAPK31.21143541
41ATR1.21130271
42PKN21.20911261
43PIM11.18268818
44ILK1.17843967
45KIT1.17121894
46ZAP701.16198336
47PLK11.07841323
48TXK1.06338297
49SCYL21.04304695
50CDK41.03795069
51PAK41.01947849
52BLK0.96817197
53MAP2K30.94724180
54MAP3K80.94685205
55BRAF0.93340510
56TAF10.92047192
57ARAF0.90726221
58TTK0.88492793
59PLK40.88274687
60TYK20.86173547
61JAK30.85970264
62STK40.83369328
63IKBKB0.82962308
64CDK80.79962317
65BCKDK0.78992504
66SYK0.76781490
67CSF1R0.75985946
68GRK60.74645148
69CSNK2A20.74627097
70AURKA0.74568245
71RPS6KA50.73244988
72DAPK30.71392568
73SIK10.69747250
74CDK190.68430708
75CCNB10.66709755
76TESK10.66702894
77CHEK10.66102921
78MKNK20.65906097
79CDK120.65512195
80LCK0.65074916
81NLK0.64681661
82IRAK30.64629466
83MAP3K30.64286329
84MARK30.64009543
85CSNK2A10.62207733
86CHEK20.62022297
87MAP3K130.61813636
88ITK0.60957040
89ICK0.60412800
90ZAK0.59950795
91LYN0.59375976
92MAP3K110.57884517
93PDK20.57852567
94IKBKE0.57601800
95EPHA20.57450201
96CDK60.56216559
97CLK10.55781641
98IRAK40.55496929
99TBK10.54274003
100EIF2AK20.53482663
101DYRK20.52126736
102PAK10.50508452
103BRSK10.50462701
104NME10.49998556
105PAK20.49834519
106ATM0.47905058
107PLK30.47714145
108RIPK40.46612565
109NEK10.44643203
110RPS6KL10.43561100
111RPS6KC10.43561100
112RPS6KA60.43416697
113CDK20.43334819
114MATK0.41427121
115MAPK150.40559845
116ABL20.39052618
117IRAK20.38857279
118MAP2K20.38709464
119MAPKAPK20.38606912
120RPS6KA10.38445437
121CAMKK10.37715729
122CDK10.36755172
123TYRO30.36537166
124MAP2K60.35978019
125CSNK1E0.34059191
126PTK60.34031288
127CDK90.33354412
128PRKCI0.32891845
129TGFBR20.31531767
130MUSK0.30633472
131MTOR0.29300308
132AKT20.28510169
133STK240.25383459

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030107.07572665
2DNA replication_Homo sapiens_hsa030304.13616475
3Mismatch repair_Homo sapiens_hsa034303.43945028
4Proteasome_Homo sapiens_hsa030503.03273260
5Spliceosome_Homo sapiens_hsa030403.00967969
6RNA polymerase_Homo sapiens_hsa030202.90965866
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.59780605
8Homologous recombination_Homo sapiens_hsa034402.52270276
9Base excision repair_Homo sapiens_hsa034102.47362853
10Nucleotide excision repair_Homo sapiens_hsa034202.45628379
11RNA transport_Homo sapiens_hsa030132.23947420
12Pyrimidine metabolism_Homo sapiens_hsa002402.21685802
13One carbon pool by folate_Homo sapiens_hsa006701.79859191
14Cell cycle_Homo sapiens_hsa041101.77718946
15Non-homologous end-joining_Homo sapiens_hsa034501.75097185
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.67551304
17Primary immunodeficiency_Homo sapiens_hsa053401.64865889
18Fanconi anemia pathway_Homo sapiens_hsa034601.62841452
19Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.60017487
20RNA degradation_Homo sapiens_hsa030181.58852507
21Cardiac muscle contraction_Homo sapiens_hsa042601.56226535
22Protein export_Homo sapiens_hsa030601.52611923
23p53 signaling pathway_Homo sapiens_hsa041151.37843865
24Systemic lupus erythematosus_Homo sapiens_hsa053221.37725190
25Basal transcription factors_Homo sapiens_hsa030221.32054027
26Antigen processing and presentation_Homo sapiens_hsa046121.26728376
27Parkinsons disease_Homo sapiens_hsa050121.22745489
28Oxidative phosphorylation_Homo sapiens_hsa001901.12549578
29mRNA surveillance pathway_Homo sapiens_hsa030151.09300928
30Herpes simplex infection_Homo sapiens_hsa051681.09051774
31Epstein-Barr virus infection_Homo sapiens_hsa051691.07764426
32Purine metabolism_Homo sapiens_hsa002301.01301918
33Huntingtons disease_Homo sapiens_hsa050161.01244990
34Cyanoamino acid metabolism_Homo sapiens_hsa004600.93315524
35Viral carcinogenesis_Homo sapiens_hsa052030.87886983
36Hematopoietic cell lineage_Homo sapiens_hsa046400.87416626
37Measles_Homo sapiens_hsa051620.82538470
38Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.80998451
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.80820661
40NF-kappa B signaling pathway_Homo sapiens_hsa040640.78094066
41Intestinal immune network for IgA production_Homo sapiens_hsa046720.77861922
42Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77639053
43HTLV-I infection_Homo sapiens_hsa051660.72979055
44Legionellosis_Homo sapiens_hsa051340.72450696
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.70527516
46Sulfur relay system_Homo sapiens_hsa041220.70404922
47Pentose phosphate pathway_Homo sapiens_hsa000300.67967835
48Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.67959185
49Alzheimers disease_Homo sapiens_hsa050100.66210846
50Allograft rejection_Homo sapiens_hsa053300.62210368
51Folate biosynthesis_Homo sapiens_hsa007900.61936209
52N-Glycan biosynthesis_Homo sapiens_hsa005100.61814621
53Small cell lung cancer_Homo sapiens_hsa052220.61481603
54Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.60690913
55Apoptosis_Homo sapiens_hsa042100.60565335
56Thyroid cancer_Homo sapiens_hsa052160.57418153
57RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.56864637
58Leishmaniasis_Homo sapiens_hsa051400.56783286
59Shigellosis_Homo sapiens_hsa051310.51972754
60Hepatitis B_Homo sapiens_hsa051610.51296184
61B cell receptor signaling pathway_Homo sapiens_hsa046620.49906823
62Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.49887506
63Jak-STAT signaling pathway_Homo sapiens_hsa046300.49705751
64Biosynthesis of amino acids_Homo sapiens_hsa012300.48972667
65NOD-like receptor signaling pathway_Homo sapiens_hsa046210.48407691
66Acute myeloid leukemia_Homo sapiens_hsa052210.48283841
67Alcoholism_Homo sapiens_hsa050340.47663114
68Glutathione metabolism_Homo sapiens_hsa004800.47598716
69Asthma_Homo sapiens_hsa053100.47002107
70Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46516283
71Non-small cell lung cancer_Homo sapiens_hsa052230.46114013
72Graft-versus-host disease_Homo sapiens_hsa053320.44829168
73T cell receptor signaling pathway_Homo sapiens_hsa046600.43463943
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.43296444
75Carbon metabolism_Homo sapiens_hsa012000.42750224
76Metabolic pathways_Homo sapiens_hsa011000.41560442
77Influenza A_Homo sapiens_hsa051640.40711818
78Viral myocarditis_Homo sapiens_hsa054160.40151059
79Pyruvate metabolism_Homo sapiens_hsa006200.39793431
80Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.39723339
81Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.39563556
82Notch signaling pathway_Homo sapiens_hsa043300.38574591
83MicroRNAs in cancer_Homo sapiens_hsa052060.38300480
84Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.38052594
85Drug metabolism - other enzymes_Homo sapiens_hsa009830.37715509
86Chronic myeloid leukemia_Homo sapiens_hsa052200.37414472
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.36277835
88Toxoplasmosis_Homo sapiens_hsa051450.33305170
89Vitamin digestion and absorption_Homo sapiens_hsa049770.31193837
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.30848164
91Colorectal cancer_Homo sapiens_hsa052100.30244353
92Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.28935761
93Pancreatic cancer_Homo sapiens_hsa052120.28875572
94Renal cell carcinoma_Homo sapiens_hsa052110.28794149
95Cysteine and methionine metabolism_Homo sapiens_hsa002700.28513472
96Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.28135584
97Bladder cancer_Homo sapiens_hsa052190.27603644
98Pathways in cancer_Homo sapiens_hsa052000.27581722
99Basal cell carcinoma_Homo sapiens_hsa052170.27159452
100Autoimmune thyroid disease_Homo sapiens_hsa053200.26584095
101HIF-1 signaling pathway_Homo sapiens_hsa040660.25898555
102Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.24952288
103Platelet activation_Homo sapiens_hsa046110.24565941
104Arachidonic acid metabolism_Homo sapiens_hsa005900.24406427
105Other glycan degradation_Homo sapiens_hsa005110.24173782
106TGF-beta signaling pathway_Homo sapiens_hsa043500.24042424
107Malaria_Homo sapiens_hsa051440.22921293
108Pertussis_Homo sapiens_hsa051330.22449553
109Osteoclast differentiation_Homo sapiens_hsa043800.22438230
110VEGF signaling pathway_Homo sapiens_hsa043700.20691639
111Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.19079394
112Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.18175696
113Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.17618444
114Oocyte meiosis_Homo sapiens_hsa041140.17507422
115Wnt signaling pathway_Homo sapiens_hsa043100.16103517
116Fructose and mannose metabolism_Homo sapiens_hsa000510.12979134
117Hedgehog signaling pathway_Homo sapiens_hsa043400.12063824
118Tyrosine metabolism_Homo sapiens_hsa003500.09503312
119mTOR signaling pathway_Homo sapiens_hsa041500.07496189
120Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.06599660
121Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.06581835
122Melanoma_Homo sapiens_hsa052180.05985844
123Galactose metabolism_Homo sapiens_hsa000520.05975426
124Regulation of autophagy_Homo sapiens_hsa041400.02986106
125Prostate cancer_Homo sapiens_hsa052150.02194434

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