RPL32P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleoside salvage (GO:0043097)5.67561907
2pyrimidine-containing compound salvage (GO:0008655)5.67561907
3nucleotide salvage (GO:0043173)5.07882441
4regulation of B cell receptor signaling pathway (GO:0050855)4.86974823
5nucleoside salvage (GO:0043174)4.77644402
6viral transcription (GO:0019083)4.55882759
7immunoglobulin mediated immune response (GO:0016064)4.53948351
8neutrophil activation involved in immune response (GO:0002283)4.52953327
9RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.48861598
10tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.48861598
11pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174)4.34578424
12UMP metabolic process (GO:0046049)4.34578424
13pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173)4.34578424
14UMP biosynthetic process (GO:0006222)4.34578424
15translational termination (GO:0006415)4.29669160
16pyrimidine nucleoside monophosphate metabolic process (GO:0009129)4.18475053
17positive thymic T cell selection (GO:0045059)4.13224756
18CTP metabolic process (GO:0046036)4.12920967
19CTP biosynthetic process (GO:0006241)4.12920967
20translational elongation (GO:0006414)4.12766591
21positive regulation of gamma-delta T cell activation (GO:0046645)4.10624604
22regulation of B cell differentiation (GO:0045577)4.01641776
23pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)3.94378533
24positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.90250550
25pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.71195347
26cellular extravasation (GO:0045123)3.68032125
27pentose metabolic process (GO:0019321)3.66171978
28negative thymic T cell selection (GO:0045060)3.65977067
29T cell selection (GO:0045058)3.60300089
30regulation of dendritic cell antigen processing and presentation (GO:0002604)3.59925838
31positive T cell selection (GO:0043368)3.59290813
32regulation of hypersensitivity (GO:0002883)3.56222835
33B cell mediated immunity (GO:0019724)3.50395901
34negative T cell selection (GO:0043383)3.48832917
35pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.44819967
36interferon-gamma-mediated signaling pathway (GO:0060333)3.41579530
37positive regulation of B cell differentiation (GO:0045579)3.37753883
38defense response to protozoan (GO:0042832)3.36086969
39positive regulation of antigen processing and presentation (GO:0002579)3.29940284
40positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.27536408
41SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.26254623
42B cell receptor signaling pathway (GO:0050853)3.25677348
43pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.24481850
44negative regulation of interleukin-8 production (GO:0032717)3.24088595
45cellular protein complex disassembly (GO:0043624)3.21620136
46protein targeting to ER (GO:0045047)3.16466789
47cotranslational protein targeting to membrane (GO:0006613)3.16240204
48T-helper 1 type immune response (GO:0042088)3.15961511
49positive regulation of protein homooligomerization (GO:0032464)3.14140108
50negative regulation of interleukin-12 production (GO:0032695)3.12900206
51regulation of antigen processing and presentation (GO:0002577)3.11626207
52regulation of isotype switching to IgG isotypes (GO:0048302)3.10885984
53thymic T cell selection (GO:0045061)3.09044939
54pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.07872964
55behavioral response to nicotine (GO:0035095)3.03969200
56protein localization to endoplasmic reticulum (GO:0070972)3.01704822
57response to protozoan (GO:0001562)3.00675261
58lymphocyte costimulation (GO:0031294)2.99919655
59establishment of protein localization to endoplasmic reticulum (GO:0072599)2.98617131
60T cell costimulation (GO:0031295)2.97828845
61ribosomal small subunit assembly (GO:0000028)2.97813250
62organ or tissue specific immune response (GO:0002251)2.96810582
63viral life cycle (GO:0019058)2.93097319
64neutrophil mediated immunity (GO:0002446)2.92134329
65nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)2.90040490
66protein complex disassembly (GO:0043241)2.89862519
67positive regulation of defense response to virus by host (GO:0002230)2.87376730
68macromolecular complex disassembly (GO:0032984)2.81896753
69regulation of gamma-delta T cell activation (GO:0046643)2.81767241
70interferon-gamma production (GO:0032609)2.79977578
71activation of NF-kappaB-inducing kinase activity (GO:0007250)2.79818447
72diterpenoid biosynthetic process (GO:0016102)2.79276101
73regulation of germinal center formation (GO:0002634)2.73408316
74negative regulation of T-helper cell differentiation (GO:0045623)2.73278125
75negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.73278125
76pyrimidine ribonucleoside biosynthetic process (GO:0046132)2.73228253
77myeloid cell activation involved in immune response (GO:0002275)2.72957852
78innate immune response in mucosa (GO:0002227)2.72863420
79positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.71938911
80negative regulation of B cell proliferation (GO:0030889)2.71340341
81neutrophil activation (GO:0042119)2.71134497
82purinergic nucleotide receptor signaling pathway (GO:0035590)2.70910513
83negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.70536510
84pentose-phosphate shunt (GO:0006098)2.70511213
85positive regulation of mast cell activation (GO:0033005)2.69333627
86regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.67802937
87response to peptidoglycan (GO:0032494)2.67775865
88hepatocyte apoptotic process (GO:0097284)2.67347792
89regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)2.66570527
90positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO2.66570527
91positive regulation of T-helper 1 type immune response (GO:0002827)2.65857633
92regulation of activation of Janus kinase activity (GO:0010533)2.64643379
93regulation of mast cell activation (GO:0033003)2.63803646
94regulation of B cell mediated immunity (GO:0002712)2.60864447
95cellular response to exogenous dsRNA (GO:0071360)2.59913617
96regulation of B cell activation (GO:0050864)2.59713345
97regulation of T-helper 1 type immune response (GO:0002825)2.59326607
98regulation of B cell apoptotic process (GO:0002902)2.59312283
99glycosylceramide metabolic process (GO:0006677)2.58882636
100regulation of alpha-beta T cell proliferation (GO:0046640)2.58460028

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human6.52285191
2CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human4.37678938
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.09354363
4BP1_19119308_ChIP-ChIP_Hs578T_Human4.07012738
5IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.94538516
6IKZF1_21737484_ChIP-ChIP_HCT116_Human3.49823564
7STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse3.36197545
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.11873991
9E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.00115488
10SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.73646039
11RUNX_20019798_ChIP-Seq_JUKART_Human2.64602802
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.48041242
13PCGF2_27294783_Chip-Seq_NPCs_Mouse2.38404808
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.29806669
15MYB_26560356_Chip-Seq_TH2_Human2.23049306
16RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.20883734
17E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.16947134
18SPI1_23547873_ChIP-Seq_NB4_Human2.12437187
19IRF8_27001747_Chip-Seq_BMDM_Mouse2.08819894
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.02004462
21MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.94695551
22STAT6_21828071_ChIP-Seq_BEAS2B_Human1.88001791
23IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.85899343
24GATA3_26560356_Chip-Seq_TH2_Human1.82346284
25FLI1_27457419_Chip-Seq_LIVER_Mouse1.78859508
26STAT1_20625510_ChIP-Seq_HELA_Human1.78315216
27SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.76390292
28VDR_21846776_ChIP-Seq_THP-1_Human1.75869003
29CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.71293823
30MYB_26560356_Chip-Seq_TH1_Human1.67735241
31VDR_24763502_ChIP-Seq_THP-1_Human1.66296074
32UTX_26944678_Chip-Seq_JUKART_Human1.61362019
33ELF1_20517297_ChIP-Seq_JURKAT_Human1.59719806
34LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.58966637
35MAF_26560356_Chip-Seq_TH1_Human1.56471812
36STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.51012432
37RUNX1_22412390_ChIP-Seq_EML_Mouse1.48902396
38PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44461463
39CIITA_25753668_ChIP-Seq_RAJI_Human1.41849962
40MYC_22102868_ChIP-Seq_BL_Human1.41763777
41SCL_19346495_ChIP-Seq_HPC-7_Human1.40127521
42BCL6_27268052_Chip-Seq_Bcells_Human1.39874839
43SPI1_23127762_ChIP-Seq_K562_Human1.39842863
44PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.38835821
45LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37841471
46FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.35972776
47PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.31942540
48VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.30492726
49TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.29859814
50MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.29675743
51FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.27707245
52STAT4_19710469_ChIP-ChIP_TH1__Mouse1.27175525
53RAC3_21632823_ChIP-Seq_H3396_Human1.24202573
54BRD4_27068464_Chip-Seq_AML-cells_Mouse1.23130152
55ERA_21632823_ChIP-Seq_H3396_Human1.20801581
56GATA3_27048872_Chip-Seq_THYMUS_Human1.19589872
57MAF_26560356_Chip-Seq_TH2_Human1.18546922
58P300_27268052_Chip-Seq_Bcells_Human1.17707117
59VDR_24787735_ChIP-Seq_THP-1_Human1.16681623
60RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.15309828
61EGR1_23403033_ChIP-Seq_LIVER_Mouse1.14793574
62GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.14777273
63P68_20966046_ChIP-Seq_HELA_Human1.14221211
64E2F1_20622854_ChIP-Seq_HELA_Human1.12337583
65SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.10607212
66RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.08438164
67BCOR_27268052_Chip-Seq_Bcells_Human1.07606844
68NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.05456187
69TP53_16413492_ChIP-PET_HCT116_Human1.05066641
70FOXP3_21729870_ChIP-Seq_TREG_Human1.04976672
71PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.04460465
72VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.04185781
73MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.04093756
74SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.03303948
75EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.03051928
76CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.00527987
77RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.99811072
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.99775828
79NFE2_27457419_Chip-Seq_LIVER_Mouse0.99256520
80SUZ12_27294783_Chip-Seq_NPCs_Mouse0.96595600
81VDR_23849224_ChIP-Seq_CD4+_Human0.94494519
82GATA3_21878914_ChIP-Seq_MCF-7_Human0.93607005
83PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.91599313
84IRF1_19129219_ChIP-ChIP_H3396_Human0.91355241
85PHF8_20622854_ChIP-Seq_HELA_Human0.91125308
86GATA3_26560356_Chip-Seq_TH1_Human0.90732074
87CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.90724488
88FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90320925
89SPI1_20517297_ChIP-Seq_HL60_Human0.89381782
90CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.88782064
91PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.86953364
92VDR_22108803_ChIP-Seq_LS180_Human0.86335201
93GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86103759
94GABP_17652178_ChIP-ChIP_JURKAT_Human0.85705928
95FOXH1_21741376_ChIP-Seq_ESCs_Human0.84383767
96P53_21459846_ChIP-Seq_SAOS-2_Human0.81087389
97KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.79246486
98KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.79246486
99KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.79246486
100GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.78848491

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation5.32733805
2MP0003806_abnormal_nucleotide_metabolis4.02426009
3MP0006292_abnormal_olfactory_placode3.75875494
4MP0003950_abnormal_plasma_membrane3.62577071
5MP0003724_increased_susceptibility_to3.20664141
6MP0006082_CNS_inflammation2.65402104
7MP0009278_abnormal_bone_marrow2.54267401
8MP0001800_abnormal_humoral_immune2.52437768
9MP0001545_abnormal_hematopoietic_system2.44958802
10MP0005397_hematopoietic_system_phenotyp2.44958802
11MP0008057_abnormal_DNA_replication2.44926110
12MP0005000_abnormal_immune_tolerance2.32753949
13MP0005387_immune_system_phenotype2.30784735
14MP0001790_abnormal_immune_system2.30784735
15MP0006072_abnormal_retinal_apoptosis2.25642916
16MP0005671_abnormal_response_to2.25421376
17MP0002452_abnormal_antigen_presenting2.25393790
18MP0002723_abnormal_immune_serum2.24328071
19MP0001873_stomach_inflammation2.24247346
20MP0003646_muscle_fatigue2.21600779
21MP0000685_abnormal_immune_system2.13904819
22MP0008875_abnormal_xenobiotic_pharmacok2.11312395
23MP0005310_abnormal_salivary_gland2.07786471
24MP0003436_decreased_susceptibility_to2.03467694
25MP0003303_peritoneal_inflammation1.99635698
26MP0002419_abnormal_innate_immunity1.97627129
27MP0002420_abnormal_adaptive_immunity1.96192847
28MP0005025_abnormal_response_to1.94524838
29MP0001819_abnormal_immune_cell1.93827889
30MP0005451_abnormal_body_composition1.87649988
31MP0002148_abnormal_hypersensitivity_rea1.87116231
32MP0009764_decreased_sensitivity_to1.74921222
33MP0009785_altered_susceptibility_to1.73722177
34MP0001853_heart_inflammation1.71957099
35MP0000716_abnormal_immune_system1.66539110
36MP0002398_abnormal_bone_marrow1.66376143
37MP0010155_abnormal_intestine_physiology1.59654145
38MP0002396_abnormal_hematopoietic_system1.55373394
39MP0002163_abnormal_gland_morphology1.46015226
40MP0000689_abnormal_spleen_morphology1.43580366
41MP0002429_abnormal_blood_cell1.41873539
42MP0002405_respiratory_system_inflammati1.41211726
43MP0003763_abnormal_thymus_physiology1.35582830
44MP0001986_abnormal_taste_sensitivity1.30689434
45MP0004808_abnormal_hematopoietic_stem1.28278221
46MP0001348_abnormal_lacrimal_gland1.23476289
47MP0002876_abnormal_thyroid_physiology1.22518324
48MP0002722_abnormal_immune_system1.21538885
49MP0008872_abnormal_physiological_respon1.20715564
50MP0001845_abnormal_inflammatory_respons1.18547735
51MP0009379_abnormal_foot_pigmentation1.18086008
52MP0000703_abnormal_thymus_morphology1.15061347
53MP0002090_abnormal_vision1.14415010
54MP0005670_abnormal_white_adipose1.13681317
55MP0001663_abnormal_digestive_system1.07397955
56MP0003866_abnormal_defecation0.96560422
57MP0002138_abnormal_hepatobiliary_system0.95447498
58MP0003656_abnormal_erythrocyte_physiolo0.94782605
59MP0005464_abnormal_platelet_physiology0.92331919
60MP0005266_abnormal_metabolism0.91991266
61MP0005365_abnormal_bile_salt0.91976362
62MP0008469_abnormal_protein_level0.91429997
63MP0005645_abnormal_hypothalamus_physiol0.90975289
64MP0001533_abnormal_skeleton_physiology0.89715425
65MP0004142_abnormal_muscle_tone0.88085368
66MP0000015_abnormal_ear_pigmentation0.85920691
67MP0000383_abnormal_hair_follicle0.84289835
68MP0002095_abnormal_skin_pigmentation0.81229946
69MP0002019_abnormal_tumor_incidence0.80751144
70MP0008873_increased_physiological_sensi0.80444266
71MP0003191_abnormal_cellular_cholesterol0.79455837
72MP0005551_abnormal_eye_electrophysiolog0.78810468
73MP0002006_tumorigenesis0.76508307
74MP0002998_abnormal_bone_remodeling0.76041999
75MP0009333_abnormal_splenocyte_physiolog0.74989286
76MP0002933_joint_inflammation0.74181382
77MP0001501_abnormal_sleep_pattern0.73422547
78MP0005084_abnormal_gallbladder_morpholo0.73090696
79MP0005646_abnormal_pituitary_gland0.71266980
80MP0002166_altered_tumor_susceptibility0.69744199
81MP0001919_abnormal_reproductive_system0.68806946
82MP0002332_abnormal_exercise_endurance0.67881003
83MP0005253_abnormal_eye_physiology0.65986751
84MP0009840_abnormal_foam_cell0.65753479
85MP0010386_abnormal_urinary_bladder0.64973383
86MP0004782_abnormal_surfactant_physiolog0.63942674
87MP0005167_abnormal_blood-brain_barrier0.63702624
88MP0006036_abnormal_mitochondrial_physio0.58981195
89MP0004130_abnormal_muscle_cell0.58716975
90MP0005389_reproductive_system_phenotype0.57533726
91MP0001542_abnormal_bone_strength0.56023579
92MP0008995_early_reproductive_senescence0.55009493
93MP0009115_abnormal_fat_cell0.54687923
94MP0000465_gastrointestinal_hemorrhage0.54262507
95MP0000343_altered_response_to0.53568309
96MP0008877_abnormal_DNA_methylation0.51240880
97MP0008789_abnormal_olfactory_epithelium0.50853847
98MP0002102_abnormal_ear_morphology0.49971032
99MP0004742_abnormal_vestibular_system0.49060915
100MP0005379_endocrine/exocrine_gland_phen0.47823809

Predicted human phenotypes

RankGene SetZ-score
1Panhypogammaglobulinemia (HP:0003139)4.35698518
2Abnormal delayed hypersensitivity skin test (HP:0002963)4.09343774
3Abnormal number of erythroid precursors (HP:0012131)3.93965108
4Abnormality of cells of the erythroid lineage (HP:0012130)3.85289430
5Hip dysplasia (HP:0001385)3.83699820
6Stomatitis (HP:0010280)3.51626649
7Elevated erythrocyte sedimentation rate (HP:0003565)3.51028607
8Myositis (HP:0100614)3.35717802
9Thrombocytosis (HP:0001894)3.25356943
10Agammaglobulinemia (HP:0004432)3.15468913
11Meningitis (HP:0001287)3.11874520
12Absent rod-and cone-mediated responses on ERG (HP:0007688)3.07805370
13Exertional dyspnea (HP:0002875)3.06709880
14Hyperglycinemia (HP:0002154)3.03820203
15Stomach cancer (HP:0012126)3.03433999
16Abnormality of the prostate (HP:0008775)2.97469895
17Mediastinal lymphadenopathy (HP:0100721)2.97403204
18Vasculitis (HP:0002633)2.96143805
19Recurrent cutaneous fungal infections (HP:0011370)2.96074067
20Chronic mucocutaneous candidiasis (HP:0002728)2.96074067
21Retrobulbar optic neuritis (HP:0100654)2.89066945
22Optic neuritis (HP:0100653)2.89066945
23Hypoplasia of the pons (HP:0012110)2.85436421
24Concave nail (HP:0001598)2.83941528
25Abnormality of the pons (HP:0007361)2.80968037
26Poor eye contact (HP:0000817)2.80463986
27Recurrent bacterial skin infections (HP:0005406)2.77914654
28Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.77318979
29Obstructive lung disease (HP:0006536)2.73452516
30Chronic obstructive pulmonary disease (HP:0006510)2.73452516
31Recurrent fungal infections (HP:0002841)2.71965779
32Increased hepatocellular lipid droplets (HP:0006565)2.71751838
33Pustule (HP:0200039)2.70091774
34Lipid accumulation in hepatocytes (HP:0006561)2.68746492
35Difficulty running (HP:0009046)2.66840388
36Alveolar cell carcinoma (HP:0006519)2.60640131
37Autoimmune thrombocytopenia (HP:0001973)2.59042479
38Gastrointestinal infarctions (HP:0005244)2.58647586
39Spondylolisthesis (HP:0003302)2.57415600
40Type 2 muscle fiber atrophy (HP:0003554)2.55297408
41Recurrent viral infections (HP:0004429)2.53635058
42Pancreatic cysts (HP:0001737)2.48581368
43Chest pain (HP:0100749)2.48153696
44Abnormality of the periventricular white matter (HP:0002518)2.46110557
45Encephalitis (HP:0002383)2.45796733
46Congenital, generalized hypertrichosis (HP:0004540)2.44808026
47Asplenia (HP:0001746)2.44178250
48Keratitis (HP:0000491)2.43837566
49Aplasia/Hypoplasia of the spleen (HP:0010451)2.43652623
50Pulmonary infiltrates (HP:0002113)2.42078717
51Orchitis (HP:0100796)2.37923576
52Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.35975887
53Neoplasm of the tracheobronchial system (HP:0100552)2.32839129
54Gangrene (HP:0100758)2.30473581
55Hemoptysis (HP:0002105)2.29867182
56Poor suck (HP:0002033)2.25437441
57Colitis (HP:0002583)2.25156668
58Recurrent skin infections (HP:0001581)2.22697907
59Abnormality of T cell physiology (HP:0011840)2.22667423
60Decreased central vision (HP:0007663)2.22206665
61Renal Fanconi syndrome (HP:0001994)2.20766322
62Abnormal rod and cone electroretinograms (HP:0008323)2.19818592
63Spontaneous abortion (HP:0005268)2.19594390
64Recurrent abscess formation (HP:0002722)2.18528066
65Arterial thrombosis (HP:0004420)2.17314057
66Muscle fiber atrophy (HP:0100295)2.15696375
67Attenuation of retinal blood vessels (HP:0007843)2.14829827
68Hypochromic anemia (HP:0001931)2.09423919
69Keratoconjunctivitis (HP:0001096)2.09384994
70Mitochondrial inheritance (HP:0001427)2.08053758
71Abnormality of the pleura (HP:0002103)2.07362917
72Parakeratosis (HP:0001036)2.06652980
73Decreased electroretinogram (ERG) amplitude (HP:0000654)2.05755060
74Macrocytic anemia (HP:0001972)2.03675272
75Increased intramyocellular lipid droplets (HP:0012240)2.03435136
76Abnormal drinking behavior (HP:0030082)2.02296748
77Polydipsia (HP:0001959)2.02296748
78IgG deficiency (HP:0004315)2.01388688
79Recurrent gram-negative bacterial infections (HP:0005420)2.01348374
80Amaurosis fugax (HP:0100576)2.01031057
81Pulmonary fibrosis (HP:0002206)2.00455479
82Increased muscle lipid content (HP:0009058)1.99712526
83Episodic fever (HP:0001954)1.98975884
84Gastrointestinal stroma tumor (HP:0100723)1.95671118
85Polyuria (HP:0000103)1.95467351
86Viral hepatitis (HP:0006562)1.94109969
87Congenital stationary night blindness (HP:0007642)1.93864921
88Pulmonary embolism (HP:0002204)1.93030858
89Keratoconjunctivitis sicca (HP:0001097)1.92766897
90Restrictive lung disease (HP:0002091)1.91731812
91Eosinophilia (HP:0001880)1.90320771
92Amyloidosis (HP:0011034)1.88818936
93Pallor (HP:0000980)1.88646756
94Metaphyseal dysplasia (HP:0100255)1.88016852
95Urticaria (HP:0001025)1.87530122
96Tinnitus (HP:0000360)1.84574096
97Pancreatic fibrosis (HP:0100732)1.83282701
98Polyneuropathy (HP:0001271)1.82183847
99Decreased circulating renin level (HP:0003351)1.81436400
100Acute lymphatic leukemia (HP:0006721)1.79975504

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.46197099
2ZAK3.84310143
3RIPK43.70389604
4BMPR23.46502922
5CSF1R3.05194421
6FLT32.84012304
7STK162.57063541
8ADRBK22.55953306
9PIK3CG2.35449744
10KIT2.32064168
11TAOK32.26843702
12IKBKB2.23491843
13JAK32.19403215
14NME22.13946883
15TYK22.05684045
16GRK72.01309484
17MAP2K31.95657757
18TXK1.76100280
19BLK1.75711892
20SYK1.65187452
21BTK1.65075130
22LIMK11.60361638
23BRD41.56145355
24LYN1.54015576
25TEC1.38549304
26LCK1.32154605
27TLK11.31391186
28PRKCQ1.30737030
29MAP3K31.30164604
30PTK2B1.29410362
31ITK1.21601908
32TNK21.15589447
33IKBKE1.15085621
34PINK11.14332787
35SGK21.10067400
36PIM11.06593714
37RPS6KA51.02615916
38IRAK40.98845684
39FES0.98385555
40SGK30.95186638
41EPHB10.94885744
42PASK0.91887430
43CSK0.91849743
44PDK10.90365724
45GRK10.88641813
46AKT30.85746622
47MATK0.83449848
48CDC42BPA0.83189533
49SIK20.82979050
50JAK10.82255840
51CDK40.82016369
52RPS6KA10.79508039
53INSRR0.78026491
54IRAK10.76907752
55ABL10.68540627
56TBK10.67645287
57RPS6KA60.65275130
58MARK30.64924889
59SGK2230.64455835
60SGK4940.64455835
61PKN10.63333675
62HCK0.60776291
63RPS6KC10.60341011
64RPS6KL10.60341011
65MAPK70.58526602
66MAPK120.57126028
67ICK0.56564905
68PRKCE0.56533409
69MAPK30.48621618
70JAK20.48150746
71MAPK150.47805967
72GRK60.47326498
73CDK80.46776323
74FYN0.45324895
75RPS6KB20.45084923
76CSNK2A20.44297524
77NUAK10.43501840
78CAMKK10.43343197
79CHUK0.42317809
80LRRK20.41660934
81TIE10.41647356
82BCKDK0.41371678
83CAMKK20.40342466
84NLK0.38599183
85DYRK30.38454227
86CAMK10.36470359
87MAP3K130.36043635
88BRAF0.35585228
89SGK10.32999313
90PAK10.32253377
91ZAP700.32136894
92CDK30.31490857
93MKNK20.30756725
94PRKCA0.30377373
95MOS0.28849485
96MARK20.27626299
97VRK10.27492459
98MAPK110.27243079
99FRK0.26865916
100EGFR0.26546542

Predicted pathways (KEGG)

RankGene SetZ-score
1Asthma_Homo sapiens_hsa053105.52914935
2Allograft rejection_Homo sapiens_hsa053304.64921442
3Autoimmune thyroid disease_Homo sapiens_hsa053204.40364611
4Intestinal immune network for IgA production_Homo sapiens_hsa046724.18726443
5Graft-versus-host disease_Homo sapiens_hsa053324.15751100
6Type I diabetes mellitus_Homo sapiens_hsa049403.52771093
7Staphylococcus aureus infection_Homo sapiens_hsa051502.99873078
8Inflammatory bowel disease (IBD)_Homo sapiens_hsa053212.86978062
9Leishmaniasis_Homo sapiens_hsa051402.80814880
10Antigen processing and presentation_Homo sapiens_hsa046122.69224349
11Ribosome_Homo sapiens_hsa030102.65510500
12Viral myocarditis_Homo sapiens_hsa054162.33600123
13Primary immunodeficiency_Homo sapiens_hsa053402.31212252
14Hematopoietic cell lineage_Homo sapiens_hsa046402.04294722
15Sulfur relay system_Homo sapiens_hsa041222.00475244
16Rheumatoid arthritis_Homo sapiens_hsa053231.95920223
17Osteoclast differentiation_Homo sapiens_hsa043801.46072357
18Systemic lupus erythematosus_Homo sapiens_hsa053221.42274638
19Drug metabolism - other enzymes_Homo sapiens_hsa009831.40432834
20Tuberculosis_Homo sapiens_hsa051521.39760017
21Influenza A_Homo sapiens_hsa051641.37533781
22SNARE interactions in vesicular transport_Homo sapiens_hsa041301.32621956
23Toxoplasmosis_Homo sapiens_hsa051451.31081980
24Herpes simplex infection_Homo sapiens_hsa051681.15046716
25Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.13691038
26B cell receptor signaling pathway_Homo sapiens_hsa046621.10774303
27Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.09149278
28Measles_Homo sapiens_hsa051621.04393313
29NOD-like receptor signaling pathway_Homo sapiens_hsa046211.00126444
30Jak-STAT signaling pathway_Homo sapiens_hsa046300.98513921
31Pyrimidine metabolism_Homo sapiens_hsa002400.97265983
32Linoleic acid metabolism_Homo sapiens_hsa005910.86192664
33Phagosome_Homo sapiens_hsa041450.82602452
34Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.82379082
35NF-kappa B signaling pathway_Homo sapiens_hsa040640.70797845
36Legionellosis_Homo sapiens_hsa051340.67040934
37RNA polymerase_Homo sapiens_hsa030200.65673799
38Toll-like receptor signaling pathway_Homo sapiens_hsa046200.64186846
39Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64013417
40Regulation of autophagy_Homo sapiens_hsa041400.63651908
41Phototransduction_Homo sapiens_hsa047440.63439388
42Other glycan degradation_Homo sapiens_hsa005110.62835354
43Oxidative phosphorylation_Homo sapiens_hsa001900.61338429
44Pentose phosphate pathway_Homo sapiens_hsa000300.59203206
45Apoptosis_Homo sapiens_hsa042100.59171825
46Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56472892
47T cell receptor signaling pathway_Homo sapiens_hsa046600.56171742
48Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.54277802
49DNA replication_Homo sapiens_hsa030300.54058168
50RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.52625046
51Ether lipid metabolism_Homo sapiens_hsa005650.51683273
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.51655675
53alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.51270264
54Chemokine signaling pathway_Homo sapiens_hsa040620.50475421
55Epstein-Barr virus infection_Homo sapiens_hsa051690.50224305
56Collecting duct acid secretion_Homo sapiens_hsa049660.48455545
57Parkinsons disease_Homo sapiens_hsa050120.47663911
58Arachidonic acid metabolism_Homo sapiens_hsa005900.47623739
59Olfactory transduction_Homo sapiens_hsa047400.47174775
60One carbon pool by folate_Homo sapiens_hsa006700.46696358
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.45678623
62Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.45501379
63Dorso-ventral axis formation_Homo sapiens_hsa043200.44585400
64Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.43812558
65Nitrogen metabolism_Homo sapiens_hsa009100.43728690
66Carbohydrate digestion and absorption_Homo sapiens_hsa049730.40961750
67African trypanosomiasis_Homo sapiens_hsa051430.38862847
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.38133936
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.36209047
70HTLV-I infection_Homo sapiens_hsa051660.34311312
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.33282952
72Base excision repair_Homo sapiens_hsa034100.31530612
73Platelet activation_Homo sapiens_hsa046110.31493943
74Pertussis_Homo sapiens_hsa051330.30885590
75Caffeine metabolism_Homo sapiens_hsa002320.29693456
76p53 signaling pathway_Homo sapiens_hsa041150.29588161
77Nucleotide excision repair_Homo sapiens_hsa034200.27977803
78Inositol phosphate metabolism_Homo sapiens_hsa005620.26665712
79Huntingtons disease_Homo sapiens_hsa050160.26358045
80Malaria_Homo sapiens_hsa051440.24128683
81Sphingolipid metabolism_Homo sapiens_hsa006000.23895379
82Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.23780533
83Butanoate metabolism_Homo sapiens_hsa006500.23646263
84TNF signaling pathway_Homo sapiens_hsa046680.21990676
85Homologous recombination_Homo sapiens_hsa034400.19397240
86Glycerolipid metabolism_Homo sapiens_hsa005610.19135020
87Tryptophan metabolism_Homo sapiens_hsa003800.18313870
88Steroid hormone biosynthesis_Homo sapiens_hsa001400.17233430
89Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.16912843
90Chemical carcinogenesis_Homo sapiens_hsa052040.15512466
91Primary bile acid biosynthesis_Homo sapiens_hsa001200.14748914
92Purine metabolism_Homo sapiens_hsa002300.14621194
93Fat digestion and absorption_Homo sapiens_hsa049750.14607976
94Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.14339945
95Alzheimers disease_Homo sapiens_hsa050100.14162825
96Non-homologous end-joining_Homo sapiens_hsa034500.13184448
97Salivary secretion_Homo sapiens_hsa049700.10439586
98Acute myeloid leukemia_Homo sapiens_hsa052210.09791603
99Selenocompound metabolism_Homo sapiens_hsa004500.09775025
100RNA degradation_Homo sapiens_hsa030180.09630821

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