RPL32P26

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ketone body metabolic process (GO:1902224)4.90687987
2cellular ketone body metabolic process (GO:0046950)4.80635502
3water-soluble vitamin biosynthetic process (GO:0042364)4.47186883
4DNA deamination (GO:0045006)4.24032039
5branched-chain amino acid catabolic process (GO:0009083)3.85131916
6cell wall macromolecule metabolic process (GO:0044036)3.85122968
7base-excision repair, AP site formation (GO:0006285)3.82320550
8inositol phosphate catabolic process (GO:0071545)3.76148171
9regulation of glucokinase activity (GO:0033131)3.69480289
10regulation of hexokinase activity (GO:1903299)3.69480289
11protein complex biogenesis (GO:0070271)3.67905466
12respiratory chain complex IV assembly (GO:0008535)3.65946828
13lactate metabolic process (GO:0006089)3.62235695
14regulation of acrosome reaction (GO:0060046)3.50277057
15negative regulation of cytosolic calcium ion concentration (GO:0051481)3.49534005
16inositol phosphate dephosphorylation (GO:0046855)3.45277323
17phosphorylated carbohydrate dephosphorylation (GO:0046838)3.45277323
18mitochondrial respiratory chain complex assembly (GO:0033108)3.44323305
19positive regulation of histone H3-K4 methylation (GO:0051571)3.41495350
20tryptophan catabolic process (GO:0006569)3.38201829
21indole-containing compound catabolic process (GO:0042436)3.38201829
22indolalkylamine catabolic process (GO:0046218)3.38201829
23cell wall macromolecule catabolic process (GO:0016998)3.37964014
24cytochrome complex assembly (GO:0017004)3.33629763
25mannosylation (GO:0097502)3.32501378
26preassembly of GPI anchor in ER membrane (GO:0016254)3.32308535
27piRNA metabolic process (GO:0034587)3.26099076
28branched-chain amino acid metabolic process (GO:0009081)3.25299076
29signal peptide processing (GO:0006465)3.24963912
30tryptophan metabolic process (GO:0006568)3.24638964
31mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.22961241
32mitochondrial respiratory chain complex I assembly (GO:0032981)3.22961241
33NADH dehydrogenase complex assembly (GO:0010257)3.22961241
34behavioral response to ethanol (GO:0048149)3.21383027
35protoporphyrinogen IX biosynthetic process (GO:0006782)3.15173131
36polyol catabolic process (GO:0046174)3.11135367
37dopamine transport (GO:0015872)3.09328328
38positive regulation of prostaglandin secretion (GO:0032308)3.08914443
39behavioral response to nicotine (GO:0035095)3.07905924
40centriole replication (GO:0007099)3.06527720
41proteasome assembly (GO:0043248)3.06304902
42C-terminal protein lipidation (GO:0006501)3.02622487
43response to pheromone (GO:0019236)3.01174747
44deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.98969317
45somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.97688498
46isotype switching (GO:0045190)2.97688498
47somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.97688498
48glucosamine-containing compound catabolic process (GO:1901072)2.97591280
49pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.96745089
50adult feeding behavior (GO:0008343)2.96552793
51platelet dense granule organization (GO:0060155)2.94142869
52regulation of protein glycosylation (GO:0060049)2.86190996
53negative regulation of interleukin-1 beta production (GO:0032691)2.86186005
54valine metabolic process (GO:0006573)2.84017644
55indolalkylamine metabolic process (GO:0006586)2.82910668
56negative regulation of cAMP-mediated signaling (GO:0043951)2.78793655
57RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.78638245
58xenobiotic catabolic process (GO:0042178)2.78061285
59negative regulation of acute inflammatory response (GO:0002674)2.77800981
60aspartate family amino acid catabolic process (GO:0009068)2.77471170
61synapsis (GO:0007129)2.75911980
62regulation of ER to Golgi vesicle-mediated transport (GO:0060628)2.73548256
63regulation of rhodopsin mediated signaling pathway (GO:0022400)2.72234357
64aldehyde catabolic process (GO:0046185)2.71208783
65nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.70450475
66regulation of B cell apoptotic process (GO:0002902)2.69745142
67somatic diversification of immunoglobulins (GO:0016445)2.69720482
68aromatic amino acid family catabolic process (GO:0009074)2.68349778
69C-terminal protein amino acid modification (GO:0018410)2.66573586
70ubiquinone biosynthetic process (GO:0006744)2.64181414
71amino sugar catabolic process (GO:0046348)2.64130068
72rRNA modification (GO:0000154)2.60974969
73short-chain fatty acid metabolic process (GO:0046459)2.57989404
74secondary metabolite biosynthetic process (GO:0044550)2.57400316
75phosphatidylinositol acyl-chain remodeling (GO:0036149)2.55223292
76cellular response to ATP (GO:0071318)2.54827651
77rhodopsin mediated signaling pathway (GO:0016056)2.54550063
78reciprocal meiotic recombination (GO:0007131)2.53751906
79reciprocal DNA recombination (GO:0035825)2.53751906
80heme biosynthetic process (GO:0006783)2.53645165
81deoxyribonucleotide catabolic process (GO:0009264)2.53276348
82peptidyl-histidine modification (GO:0018202)2.51779800
83male meiosis (GO:0007140)2.51722872
84glutathione derivative biosynthetic process (GO:1901687)2.51173420
85glutathione derivative metabolic process (GO:1901685)2.51173420
86glucosamine-containing compound metabolic process (GO:1901071)2.49635923
87regulation of meiosis I (GO:0060631)2.49258825
88phosphatidylserine acyl-chain remodeling (GO:0036150)2.48839050
89axoneme assembly (GO:0035082)2.47561129
90protein deneddylation (GO:0000338)2.47526501
91somatic recombination of immunoglobulin gene segments (GO:0016447)2.46870824
92UDP-N-acetylglucosamine metabolic process (GO:0006047)2.46443598
93mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.45586348
94maturation of 5.8S rRNA (GO:0000460)2.45374522
95RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.44846555
96tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.44846555
97serotonin receptor signaling pathway (GO:0007210)2.44765823
98N-acetylneuraminate metabolic process (GO:0006054)2.44444381
99regulation of mitochondrial translation (GO:0070129)2.43870075
100negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.43445013

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.62825212
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.01962243
3GABP_17652178_ChIP-ChIP_JURKAT_Human2.81981485
4ZNF274_21170338_ChIP-Seq_K562_Hela2.80710324
5VDR_22108803_ChIP-Seq_LS180_Human2.55455711
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.50459482
7POU3F2_20337985_ChIP-ChIP_501MEL_Human2.41784545
8IGF1R_20145208_ChIP-Seq_DFB_Human2.34526392
9FLI1_27457419_Chip-Seq_LIVER_Mouse2.32031534
10EST1_17652178_ChIP-ChIP_JURKAT_Human2.17096380
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.15044077
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.14884381
13FUS_26573619_Chip-Seq_HEK293_Human2.14144613
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.10833237
15ELK1_19687146_ChIP-ChIP_HELA_Human2.09552270
16GBX2_23144817_ChIP-Seq_PC3_Human2.07329869
17PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse2.00263136
18GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.97640252
19EWS_26573619_Chip-Seq_HEK293_Human1.89005660
20HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.88940512
21ER_23166858_ChIP-Seq_MCF-7_Human1.87835605
22VDR_23849224_ChIP-Seq_CD4+_Human1.87363729
23SRF_21415370_ChIP-Seq_HL-1_Mouse1.86195143
24ZFP57_27257070_Chip-Seq_ESCs_Mouse1.78123739
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.75576661
26TAF15_26573619_Chip-Seq_HEK293_Human1.74152828
27EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.73993040
28JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.73641779
29PCGF2_27294783_Chip-Seq_ESCs_Mouse1.72516171
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.68418773
31SALL1_21062744_ChIP-ChIP_HESCs_Human1.67827565
32P300_19829295_ChIP-Seq_ESCs_Human1.65816978
33SOX2_19829295_ChIP-Seq_ESCs_Human1.65351613
34NANOG_19829295_ChIP-Seq_ESCs_Human1.65351613
35TP53_22573176_ChIP-Seq_HFKS_Human1.64083120
36FOXP3_21729870_ChIP-Seq_TREG_Human1.61016858
37FOXA1_25329375_ChIP-Seq_VCAP_Human1.57691686
38FOXA1_27270436_Chip-Seq_PROSTATE_Human1.57691686
39BCAT_22108803_ChIP-Seq_LS180_Human1.54470202
40ETS1_20019798_ChIP-Seq_JURKAT_Human1.54222193
41NFE2_27457419_Chip-Seq_LIVER_Mouse1.51224610
42EZH2_27294783_Chip-Seq_NPCs_Mouse1.50668206
43AR_20517297_ChIP-Seq_VCAP_Human1.47217970
44SUZ12_27294783_Chip-Seq_NPCs_Mouse1.42864527
45FOXA1_21572438_ChIP-Seq_LNCaP_Human1.42862006
46CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39000065
47CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.33933035
48CRX_20693478_ChIP-Seq_RETINA_Mouse1.33265673
49AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.32049899
50FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29909012
51AUTS2_25519132_ChIP-Seq_293T-REX_Human1.29535915
52MYC_18940864_ChIP-ChIP_HL60_Human1.29053712
53CDX2_22108803_ChIP-Seq_LS180_Human1.29015500
54IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.28792484
55CBP_20019798_ChIP-Seq_JUKART_Human1.28792484
56PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.28365353
57CTBP2_25329375_ChIP-Seq_LNCAP_Human1.27948673
58CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25999341
59CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.23842649
60LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.23405595
61PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.23030675
62TCF4_23295773_ChIP-Seq_U87_Human1.23005667
63EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.21452016
64GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21396477
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21224925
66UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.20697291
67TCF4_22108803_ChIP-Seq_LS180_Human1.19844249
68MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.19585292
69STAT3_18555785_Chip-Seq_ESCs_Mouse1.19347135
70KLF5_20875108_ChIP-Seq_MESCs_Mouse1.18352646
71MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.18129914
72HOXB7_26014856_ChIP-Seq_BT474_Human1.15655861
73HTT_18923047_ChIP-ChIP_STHdh_Human1.15029824
74IRF8_22096565_ChIP-ChIP_GC-B_Human1.14114010
75PADI4_21655091_ChIP-ChIP_MCF-7_Human1.12274869
76SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.12168229
77P53_22387025_ChIP-Seq_ESCs_Mouse1.11670550
78NANOG_18555785_Chip-Seq_ESCs_Mouse1.11426138
79PIAS1_25552417_ChIP-Seq_VCAP_Human1.11133958
80EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.09672741
81HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.09425519
82P300_18555785_Chip-Seq_ESCs_Mouse1.06992420
83ETV2_25802403_ChIP-Seq_MESCs_Mouse1.06366840
84STAT3_23295773_ChIP-Seq_U87_Human1.06191233
85HOXB4_20404135_ChIP-ChIP_EML_Mouse1.06141343
86IRF1_19129219_ChIP-ChIP_H3396_Human1.05541124
87SUZ12_18555785_Chip-Seq_ESCs_Mouse1.05197702
88NCOR_22424771_ChIP-Seq_293T_Human1.04664071
89GATA3_21878914_ChIP-Seq_MCF-7_Human1.04588701
90SMAD4_21799915_ChIP-Seq_A2780_Human1.04380893
91PHF8_20622853_ChIP-Seq_HELA_Human1.02366491
92CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.01498472
93CTCF_18555785_Chip-Seq_ESCs_Mouse1.01428307
94SOX2_18555785_Chip-Seq_ESCs_Mouse1.00454125
95SMAD3_21741376_ChIP-Seq_EPCs_Human1.00375863
96CMYC_18555785_Chip-Seq_ESCs_Mouse0.99914693
97TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.99908499
98E2F1_18555785_Chip-Seq_ESCs_Mouse0.99031847
99OCT4_21477851_ChIP-Seq_ESCs_Mouse0.98870098
100RBPJ_21746931_ChIP-Seq_IB4_Human0.98678283

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003195_calcinosis3.86773696
2MP0000372_irregular_coat_pigmentation3.45872946
3MP0005646_abnormal_pituitary_gland3.17361210
4MP0002102_abnormal_ear_morphology2.96813983
5MP0002876_abnormal_thyroid_physiology2.57666118
6MP0008877_abnormal_DNA_methylation2.56408015
7MP0008058_abnormal_DNA_repair2.54693947
8MP0005083_abnormal_biliary_tract2.46932966
9MP0008875_abnormal_xenobiotic_pharmacok2.39103918
10MP0003806_abnormal_nucleotide_metabolis2.30770060
11MP0008872_abnormal_physiological_respon2.28546088
12MP0002837_dystrophic_cardiac_calcinosis2.21604080
13MP0003718_maternal_effect2.18999131
14MP0003252_abnormal_bile_duct2.17684595
15MP0005379_endocrine/exocrine_gland_phen2.17597839
16MP0004147_increased_porphyrin_level2.17526835
17MP0005084_abnormal_gallbladder_morpholo2.17285647
18MP0005551_abnormal_eye_electrophysiolog2.14061494
19MP0003787_abnormal_imprinting2.02621232
20MP0005220_abnormal_exocrine_pancreas2.00227305
21MP0005365_abnormal_bile_salt1.89295144
22MP0006036_abnormal_mitochondrial_physio1.78534874
23MP0005075_abnormal_melanosome_morpholog1.75210906
24MP0002163_abnormal_gland_morphology1.74915773
25MP0005332_abnormal_amino_acid1.69785782
26MP0004043_abnormal_pH_regulation1.68420250
27MP0000015_abnormal_ear_pigmentation1.62248265
28MP0003172_abnormal_lysosome_physiology1.59192698
29MP0003186_abnormal_redox_activity1.56463377
30MP0005367_renal/urinary_system_phenotyp1.56279399
31MP0000516_abnormal_urinary_system1.56279399
32MP0005085_abnormal_gallbladder_physiolo1.53548890
33MP0006072_abnormal_retinal_apoptosis1.51524724
34MP0002693_abnormal_pancreas_physiology1.50856959
35MP0001968_abnormal_touch/_nociception1.49821124
36MP0002638_abnormal_pupillary_reflex1.49013987
37MP0005408_hypopigmentation1.48178264
38MP0005645_abnormal_hypothalamus_physiol1.42407199
39MP0005174_abnormal_tail_pigmentation1.40741294
40MP0010386_abnormal_urinary_bladder1.40601736
41MP0005253_abnormal_eye_physiology1.37128501
42MP0001944_abnormal_pancreas_morphology1.36754460
43MP0002090_abnormal_vision1.35349790
44MP0002928_abnormal_bile_duct1.33480344
45MP0002938_white_spotting1.31190916
46MP0005397_hematopoietic_system_phenotyp1.30734887
47MP0001545_abnormal_hematopoietic_system1.30734887
48MP0003646_muscle_fatigue1.30310585
49MP0008057_abnormal_DNA_replication1.28237297
50MP0003786_premature_aging1.26134489
51MP0009643_abnormal_urine_homeostasis1.25969041
52MP0002254_reproductive_system_inflammat1.19391845
53MP0005636_abnormal_mineral_homeostasis1.19178813
54MP0009046_muscle_twitch1.18480340
55MP0010329_abnormal_lipoprotein_level1.17147798
56MP0001905_abnormal_dopamine_level1.13804636
57MP0002277_abnormal_respiratory_mucosa1.13582686
58MP0002095_abnormal_skin_pigmentation1.12632068
59MP0004142_abnormal_muscle_tone1.11379000
60MP0006035_abnormal_mitochondrial_morpho1.11267107
61MP0005167_abnormal_blood-brain_barrier1.10754423
62MP0005395_other_phenotype1.08947752
63MP0002138_abnormal_hepatobiliary_system1.07164432
64MP0003136_yellow_coat_color1.05214474
65MP0001764_abnormal_homeostasis1.05000955
66MP0005410_abnormal_fertilization1.02324970
67MP0002909_abnormal_adrenal_gland1.02087463
68MP0009780_abnormal_chondrocyte_physiolo1.01611229
69MP0001501_abnormal_sleep_pattern0.99718076
70MP0004782_abnormal_surfactant_physiolog0.97131409
71MP0003011_delayed_dark_adaptation0.96519397
72MP0003283_abnormal_digestive_organ0.94012928
73MP0001756_abnormal_urination0.92006631
74MP0006054_spinal_hemorrhage0.87717361
75MP0001984_abnormal_olfaction0.87514473
76MP0006276_abnormal_autonomic_nervous0.86935826
77MP0010678_abnormal_skin_adnexa0.82587644
78MP0001661_extended_life_span0.82355118
79MP0003950_abnormal_plasma_membrane0.82308593
80MP0005389_reproductive_system_phenotype0.80435883
81MP0003656_abnormal_erythrocyte_physiolo0.79950272
82MP0001324_abnormal_eye_pigmentation0.79154997
83MP0000631_abnormal_neuroendocrine_gland0.78240679
84MP0000230_abnormal_systemic_arterial0.78181306
85MP0002160_abnormal_reproductive_system0.77975325
86MP0002078_abnormal_glucose_homeostasis0.77886097
87MP0000538_abnormal_urinary_bladder0.77851294
88MP0003121_genomic_imprinting0.76738729
89MP0002148_abnormal_hypersensitivity_rea0.75122260
90MP0001929_abnormal_gametogenesis0.74851191
91MP0002229_neurodegeneration0.74469379
92MP0008775_abnormal_heart_ventricle0.74045319
93MP0000639_abnormal_adrenal_gland0.73495427
94MP0001502_abnormal_circadian_rhythm0.72607491
95MP0001986_abnormal_taste_sensitivity0.72417070
96MP0009745_abnormal_behavioral_response0.71983486
97MP0005647_abnormal_sex_gland0.71824219
98MP0004484_altered_response_of0.71764993
99MP0004019_abnormal_vitamin_homeostasis0.69910302
100MP0010234_abnormal_vibrissa_follicle0.69607916

Predicted human phenotypes

RankGene SetZ-score
1Decreased central vision (HP:0007663)4.07411579
2Abnormality of aspartate family amino acid metabolism (HP:0010899)3.63443488
3Methylmalonic acidemia (HP:0002912)3.53688689
4Congenital stationary night blindness (HP:0007642)3.42596617
5Pancreatic fibrosis (HP:0100732)3.35800769
6Increased CSF lactate (HP:0002490)3.29253526
7Lipid accumulation in hepatocytes (HP:0006561)3.22659103
8Pancreatic cysts (HP:0001737)3.22205415
9Ketoacidosis (HP:0001993)3.19128299
10Decreased electroretinogram (ERG) amplitude (HP:0000654)3.18539547
11Acute necrotizing encephalopathy (HP:0006965)3.13534842
12Mitochondrial inheritance (HP:0001427)3.11627107
13Acute encephalopathy (HP:0006846)3.04634984
14True hermaphroditism (HP:0010459)3.04210166
15Increased hepatocellular lipid droplets (HP:0006565)3.02531827
16Abnormal rod and cone electroretinograms (HP:0008323)2.97388333
17Progressive macrocephaly (HP:0004481)2.97290258
183-Methylglutaconic aciduria (HP:0003535)2.95252154
19Type II lissencephaly (HP:0007260)2.94271868
20Attenuation of retinal blood vessels (HP:0007843)2.91932268
21Methylmalonic aciduria (HP:0012120)2.90299178
22Large for gestational age (HP:0001520)2.86553468
23Abnormality of vitamin B metabolism (HP:0004340)2.83644247
24Abnormal mitochondria in muscle tissue (HP:0008316)2.80352741
25Abnormality of the renal cortex (HP:0011035)2.75627926
26Abnormality of midbrain morphology (HP:0002418)2.65364766
27Molar tooth sign on MRI (HP:0002419)2.65364766
28Intestinal atresia (HP:0011100)2.64958799
29Hypothermia (HP:0002045)2.62337231
30Ketosis (HP:0001946)2.60506527
31Absent rod-and cone-mediated responses on ERG (HP:0007688)2.59836158
32Abnormality of methionine metabolism (HP:0010901)2.57973719
33Keratoconus (HP:0000563)2.51602901
34Increased corneal curvature (HP:0100692)2.51602901
35Hepatic necrosis (HP:0002605)2.49126601
36Thyroid-stimulating hormone excess (HP:0002925)2.47856423
37Abnormality of the vitamin B12 metabolism (HP:0004341)2.44645572
38Hyperglycinemia (HP:0002154)2.42679817
39Hepatocellular necrosis (HP:0001404)2.38921314
40Abnormality of the pancreatic islet cells (HP:0006476)2.37278911
41Abnormality of endocrine pancreas physiology (HP:0012093)2.37278911
42Pancreatic islet-cell hyperplasia (HP:0004510)2.33211038
43Renal cortical cysts (HP:0000803)2.25931941
44Renal Fanconi syndrome (HP:0001994)2.25458189
45Medial flaring of the eyebrow (HP:0010747)2.19772198
46Cerebellar dysplasia (HP:0007033)2.18589624
47Dicarboxylic aciduria (HP:0003215)2.18366146
48Abnormality of dicarboxylic acid metabolism (HP:0010995)2.18366146
49Cerebral edema (HP:0002181)2.17005490
50Increased serum lactate (HP:0002151)2.15349092
51Lethargy (HP:0001254)2.14949143
52Abnormality of vitamin metabolism (HP:0100508)2.14398184
53Abnormality of urine glucose concentration (HP:0011016)2.14174514
54Glycosuria (HP:0003076)2.14174514
55Cystic liver disease (HP:0006706)2.13834791
56Gaze-evoked nystagmus (HP:0000640)2.12567958
57Neoplasm of the adrenal cortex (HP:0100641)2.12054786
58Abnormality of serum amino acid levels (HP:0003112)2.07812065
59Progressive microcephaly (HP:0000253)2.07271621
60Lactic acidosis (HP:0003128)2.06486572
61Hyperglycinuria (HP:0003108)2.02617403
62Aplasia/Hypoplasia of the fovea (HP:0008060)2.00933340
63Hypoplasia of the fovea (HP:0007750)2.00933340
64Exertional dyspnea (HP:0002875)2.00540526
65Abnormality of serine family amino acid metabolism (HP:0010894)1.99319270
66Abnormality of glycine metabolism (HP:0010895)1.99319270
67Optic disc pallor (HP:0000543)1.97053726
68Congenital hepatic fibrosis (HP:0002612)1.96896313
69Abolished electroretinogram (ERG) (HP:0000550)1.96499583
70Abnormality of the pons (HP:0007361)1.94783490
71Abnormality of the renal medulla (HP:0100957)1.94207302
72Abnormality of macular pigmentation (HP:0008002)1.93239745
73Increased intramyocellular lipid droplets (HP:0012240)1.93044845
74Hyperinsulinemic hypoglycemia (HP:0000825)1.92974425
75Nephronophthisis (HP:0000090)1.92786754
76Neoplasm of the adrenal gland (HP:0100631)1.90480140
77Respiratory failure (HP:0002878)1.89609866
78Polydipsia (HP:0001959)1.89137121
79Abnormal drinking behavior (HP:0030082)1.89137121
80Tubular atrophy (HP:0000092)1.87928704
81Hypomagnesemia (HP:0002917)1.87073544
82Abnormality of the fovea (HP:0000493)1.85082246
83Lissencephaly (HP:0001339)1.84592743
84Hypokinesia (HP:0002375)1.84453475
85Hyperglycemia (HP:0003074)1.82730606
86Increased muscle lipid content (HP:0009058)1.80207731
87Furrowed tongue (HP:0000221)1.78796399
88Occipital encephalocele (HP:0002085)1.78626891
89Abnormal albumin level (HP:0012116)1.78142793
90Hypoalbuminemia (HP:0003073)1.78142793
91Progressive inability to walk (HP:0002505)1.77858011
92Hyperthyroidism (HP:0000836)1.77250614
93Inability to walk (HP:0002540)1.77126373
94Hypoglycemic coma (HP:0001325)1.75957851
95Hypoglycemic seizures (HP:0002173)1.75573022
96Abnormality of aromatic amino acid family metabolism (HP:0004338)1.74737956
97Constricted visual fields (HP:0001133)1.74610119
98Bony spicule pigmentary retinopathy (HP:0007737)1.73497478
99Polyuria (HP:0000103)1.72873481
100Abnormality of sulfur amino acid metabolism (HP:0004339)1.72538408

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.92457184
2NUAK13.23356101
3MST42.97075782
4ADRBK22.96167959
5VRK22.70243064
6EIF2AK32.67124308
7CCNB12.27799923
8ZAK2.18881488
9GRK12.17569259
10BMPR1B2.10387190
11EIF2AK11.99381099
12MAP4K21.97592396
13MKNK11.85773118
14ACVR1B1.78361128
15WNK31.77846860
16BCKDK1.73913758
17TRIM281.71770791
18LMTK21.62349491
19NEK21.52977290
20OXSR11.47610702
21MKNK21.45593675
22MAPKAPK51.37596347
23CAMKK21.37055698
24TAF11.32923459
25ERBB31.28916329
26FGFR21.25776215
27FER1.19478641
28TNIK1.17933405
29VRK11.15555353
30TLK11.14506168
31STK391.13377445
32PLK31.13029915
33WNK41.07683416
34PRKCE1.06119817
35TAOK31.03721211
36IKBKB1.03225257
37NME21.02040277
38INSRR1.00402981
39PLK20.98553010
40PBK0.97263888
41TNK20.96985160
42ADRBK10.96562994
43PDK20.94143273
44MAP3K120.93941283
45CSNK1G30.93464568
46CSNK1G10.93015068
47PINK10.92901706
48DAPK20.89201734
49PAK30.88189520
50STK38L0.84168883
51PHKG10.81895760
52PHKG20.81895760
53CSNK1G20.81105275
54WEE10.81087988
55PRKCG0.74080317
56TGFBR10.73860214
57PRKCI0.71711671
58TXK0.70457346
59CASK0.70433908
60BRSK20.68956834
61PRKCQ0.68530771
62PRKAA20.67829093
63EIF2AK20.64504149
64MAP3K40.62326769
65RPS6KA50.60272402
66MAP2K60.58323572
67KDR0.57395213
68CAMK1G0.56453435
69ABL20.55817090
70BMPR20.53103723
71CHUK0.52056990
72TRPM70.50035876
73GRK50.47882037
74TIE10.45629080
75DAPK10.44097626
76ATM0.43865287
77CAMK1D0.43726657
78CSNK1A1L0.42809236
79STK30.42749571
80NLK0.41327536
81CAMK10.41173231
82PRKG20.40724059
83PNCK0.40314734
84PTK2B0.40293159
85SCYL20.39698358
86PIK3CG0.39015211
87CSNK1A10.38363365
88LIMK10.37622893
89PRKCA0.37210597
90CAMK2D0.36876621
91CAMK2A0.35972865
92BRD40.35586784
93PIK3CA0.35547227
94PLK10.35479803
95TEC0.34269849
96TSSK60.33510786
97MARK30.32901359
98CSNK2A20.32325039
99PRKAA10.30810087
100KIT0.30260323

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.33618782
2Butanoate metabolism_Homo sapiens_hsa006502.79066298
3Maturity onset diabetes of the young_Homo sapiens_hsa049502.78189479
4Protein export_Homo sapiens_hsa030602.77780038
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.74698221
6Propanoate metabolism_Homo sapiens_hsa006402.68954678
7Phototransduction_Homo sapiens_hsa047442.52364521
8Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.46363995
9Proteasome_Homo sapiens_hsa030502.38513693
10Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.16995788
11Oxidative phosphorylation_Homo sapiens_hsa001902.16459207
12Tryptophan metabolism_Homo sapiens_hsa003802.13425387
13Homologous recombination_Homo sapiens_hsa034402.06058322
14Caffeine metabolism_Homo sapiens_hsa002321.89424254
15One carbon pool by folate_Homo sapiens_hsa006701.67638071
16Nitrogen metabolism_Homo sapiens_hsa009101.66989332
17Parkinsons disease_Homo sapiens_hsa050121.65052503
18Cyanoamino acid metabolism_Homo sapiens_hsa004601.62422769
19Peroxisome_Homo sapiens_hsa041461.61841110
20Fanconi anemia pathway_Homo sapiens_hsa034601.61598164
21Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.61132946
22RNA polymerase_Homo sapiens_hsa030201.55192023
23Fatty acid degradation_Homo sapiens_hsa000711.47851731
24Linoleic acid metabolism_Homo sapiens_hsa005911.47315604
25Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.45356673
26Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.38100771
27Sulfur metabolism_Homo sapiens_hsa009201.36684456
28Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.31923214
29Glutathione metabolism_Homo sapiens_hsa004801.30818153
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.22574099
31Basal transcription factors_Homo sapiens_hsa030221.22221448
32Non-homologous end-joining_Homo sapiens_hsa034501.20952353
33Fatty acid elongation_Homo sapiens_hsa000621.19639139
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.18180985
35Vitamin B6 metabolism_Homo sapiens_hsa007501.18054044
36Primary bile acid biosynthesis_Homo sapiens_hsa001201.16317092
37Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.14530039
38Selenocompound metabolism_Homo sapiens_hsa004501.14284305
39Ether lipid metabolism_Homo sapiens_hsa005651.14233709
40beta-Alanine metabolism_Homo sapiens_hsa004101.14137470
41Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.07950157
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.06990773
43RNA degradation_Homo sapiens_hsa030181.06810363
44Pentose and glucuronate interconversions_Homo sapiens_hsa000401.06742129
45Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.06165847
46Pyruvate metabolism_Homo sapiens_hsa006201.03079488
47Chemical carcinogenesis_Homo sapiens_hsa052041.02645927
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.02275870
49Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.00879178
50Steroid hormone biosynthesis_Homo sapiens_hsa001400.99143212
51Retinol metabolism_Homo sapiens_hsa008300.98681320
52Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.97813556
53Arachidonic acid metabolism_Homo sapiens_hsa005900.96869647
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.95862708
55Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.95744722
56Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.95156499
57SNARE interactions in vesicular transport_Homo sapiens_hsa041300.94949074
58Collecting duct acid secretion_Homo sapiens_hsa049660.93216346
59Base excision repair_Homo sapiens_hsa034100.91104850
60Purine metabolism_Homo sapiens_hsa002300.89827189
61Metabolic pathways_Homo sapiens_hsa011000.89484552
62Olfactory transduction_Homo sapiens_hsa047400.87502943
63Alzheimers disease_Homo sapiens_hsa050100.87062227
64Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.86648705
65Mismatch repair_Homo sapiens_hsa034300.86420714
66Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.86303073
67Pyrimidine metabolism_Homo sapiens_hsa002400.85398151
68Folate biosynthesis_Homo sapiens_hsa007900.84402956
69Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.83548920
70Huntingtons disease_Homo sapiens_hsa050160.82689133
71Type I diabetes mellitus_Homo sapiens_hsa049400.82340267
72Regulation of autophagy_Homo sapiens_hsa041400.68167547
73Glycerolipid metabolism_Homo sapiens_hsa005610.67024060
74Fatty acid metabolism_Homo sapiens_hsa012120.66062271
75Sphingolipid metabolism_Homo sapiens_hsa006000.63506527
76ABC transporters_Homo sapiens_hsa020100.62600789
77Nucleotide excision repair_Homo sapiens_hsa034200.60409687
78Intestinal immune network for IgA production_Homo sapiens_hsa046720.59736814
79Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56580475
80Arginine and proline metabolism_Homo sapiens_hsa003300.56018359
81Ovarian steroidogenesis_Homo sapiens_hsa049130.55139236
82RNA transport_Homo sapiens_hsa030130.54846277
83Asthma_Homo sapiens_hsa053100.53448541
84Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.52138286
85Mineral absorption_Homo sapiens_hsa049780.50197479
86Histidine metabolism_Homo sapiens_hsa003400.47561860
87Glycosaminoglycan degradation_Homo sapiens_hsa005310.47165768
88Vitamin digestion and absorption_Homo sapiens_hsa049770.44365223
89Circadian rhythm_Homo sapiens_hsa047100.44007900
90Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.43965143
91Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.43491715
92Insulin secretion_Homo sapiens_hsa049110.41850532
93Rheumatoid arthritis_Homo sapiens_hsa053230.38390110
94Lysine degradation_Homo sapiens_hsa003100.36257527
95Tyrosine metabolism_Homo sapiens_hsa003500.35812449
96Allograft rejection_Homo sapiens_hsa053300.35532786
97Sulfur relay system_Homo sapiens_hsa041220.35058065
98Starch and sucrose metabolism_Homo sapiens_hsa005000.32216011
99Taste transduction_Homo sapiens_hsa047420.31153489
100Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.30237995

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