RPL32P29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)7.50681846
2viral transcription (GO:0019083)6.67344173
3translational termination (GO:0006415)6.48468554
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.91036576
5cotranslational protein targeting to membrane (GO:0006613)5.86207080
6protein targeting to ER (GO:0045047)5.73800564
7translational elongation (GO:0006414)5.59259260
8establishment of protein localization to endoplasmic reticulum (GO:0072599)5.51761137
9protein localization to endoplasmic reticulum (GO:0070972)5.47011008
10viral life cycle (GO:0019058)4.97508077
11translational initiation (GO:0006413)4.92076509
12cellular protein complex disassembly (GO:0043624)4.78717895
13nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.74872911
14ribosomal small subunit biogenesis (GO:0042274)4.73294020
15ribosomal large subunit biogenesis (GO:0042273)4.65186038
16protein neddylation (GO:0045116)4.27953114
17translation (GO:0006412)4.07774573
18negative regulation of retinoic acid receptor signaling pathway (GO:0048387)4.06116843
19protein complex disassembly (GO:0043241)3.97543013
20NADH dehydrogenase complex assembly (GO:0010257)3.91415872
21mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.91415872
22mitochondrial respiratory chain complex I assembly (GO:0032981)3.91415872
23maturation of SSU-rRNA (GO:0030490)3.90460193
24intraciliary transport (GO:0042073)3.90380743
25pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.90058688
26cell wall macromolecule metabolic process (GO:0044036)3.90006212
27protein complex biogenesis (GO:0070271)3.89345545
28macromolecular complex disassembly (GO:0032984)3.87249377
29regulation of retinoic acid receptor signaling pathway (GO:0048385)3.86813212
30protein targeting to membrane (GO:0006612)3.77607659
31platelet dense granule organization (GO:0060155)3.71369955
32establishment of protein localization to mitochondrial membrane (GO:0090151)3.68963142
33nuclear-transcribed mRNA catabolic process (GO:0000956)3.68754937
34mitochondrial respiratory chain complex assembly (GO:0033108)3.54702881
35cullin deneddylation (GO:0010388)3.50193339
36tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.49581863
37RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.49581863
38mRNA catabolic process (GO:0006402)3.44558491
39chaperone-mediated protein transport (GO:0072321)3.43771058
40microtubule severing (GO:0051013)3.40361629
41respiratory chain complex IV assembly (GO:0008535)3.39627498
42piRNA metabolic process (GO:0034587)3.35910669
43formation of translation preinitiation complex (GO:0001731)3.31832645
44nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.25691167
45exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.22497350
46pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.21820491
47cellular component biogenesis (GO:0044085)3.20048339
48deoxyribose phosphate catabolic process (GO:0046386)3.20015439
49pyrimidine nucleotide catabolic process (GO:0006244)3.19553315
50protein deneddylation (GO:0000338)3.19382718
51energy coupled proton transport, down electrochemical gradient (GO:0015985)3.17922343
52ATP synthesis coupled proton transport (GO:0015986)3.17922343
53male meiosis I (GO:0007141)3.17578701
54ribonucleoprotein complex biogenesis (GO:0022613)3.15970243
55axoneme assembly (GO:0035082)3.11979590
56RNA catabolic process (GO:0006401)3.11773833
57DNA deamination (GO:0045006)3.07211818
58mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.05096949
59single strand break repair (GO:0000012)3.05077452
60deoxyribonucleotide catabolic process (GO:0009264)3.03945317
61positive regulation of amino acid transport (GO:0051957)3.01033394
62peroxisome fission (GO:0016559)2.99231843
63mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.97157784
64epithelial cilium movement (GO:0003351)2.97138906
65cytochrome complex assembly (GO:0017004)2.96763688
66proteasome assembly (GO:0043248)2.94277850
67negative regulation of appetite (GO:0032099)2.90765157
68negative regulation of response to food (GO:0032096)2.90765157
69aerobic respiration (GO:0009060)2.90736535
70transcription elongation from RNA polymerase III promoter (GO:0006385)2.89063378
71termination of RNA polymerase III transcription (GO:0006386)2.89063378
72negative regulation of transcription regulatory region DNA binding (GO:2000678)2.83167896
73protein targeting (GO:0006605)2.80799346
74positive regulation of histone H3-K4 methylation (GO:0051571)2.79627986
75base-excision repair, AP site formation (GO:0006285)2.78156514
76DNA methylation involved in gamete generation (GO:0043046)2.77562336
77negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.76162551
78mannosylation (GO:0097502)2.70017423
79regulation of cilium movement (GO:0003352)2.69633087
80respiratory electron transport chain (GO:0022904)2.68915922
81RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.67512795
82positive regulation of mitochondrial fission (GO:0090141)2.67116454
83electron transport chain (GO:0022900)2.65866816
84ncRNA 3-end processing (GO:0043628)2.64753677
85regulation of feeding behavior (GO:0060259)2.64045236
86peptidyl-histidine modification (GO:0018202)2.63466459
87protein K6-linked ubiquitination (GO:0085020)2.62368209
88nonmotile primary cilium assembly (GO:0035058)2.61711444
89establishment of protein localization to membrane (GO:0090150)2.58351796
90regulation of meiosis I (GO:0060631)2.56893095
91protein targeting to mitochondrion (GO:0006626)2.55751642
92chromatin remodeling at centromere (GO:0031055)2.54909805
93glucosamine-containing compound catabolic process (GO:1901072)2.54332987
94mitochondrial calcium ion transport (GO:0006851)2.54124749
95intracellular protein transmembrane import (GO:0044743)2.53803764
96protein polyglutamylation (GO:0018095)2.52785357
97establishment of protein localization to organelle (GO:0072594)2.52636990
98ribonucleoprotein complex disassembly (GO:0032988)2.52402737
99positive regulation of gastrulation (GO:2000543)2.50662008
100replication fork processing (GO:0031297)2.50264703

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.54057508
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.38769271
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.04298667
4EST1_17652178_ChIP-ChIP_JURKAT_Human3.57420061
5EZH2_22144423_ChIP-Seq_EOC_Human3.32445105
6FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.29973799
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.27818218
8SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.17699076
9RBPJ_22232070_ChIP-Seq_NCS_Mouse3.13992099
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.03083116
11VDR_22108803_ChIP-Seq_LS180_Human2.98235266
12ETS1_20019798_ChIP-Seq_JURKAT_Human2.80141981
13VDR_23849224_ChIP-Seq_CD4+_Human2.61032710
14JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.57491727
15ZNF274_21170338_ChIP-Seq_K562_Hela2.50647277
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.40739514
17ELF1_17652178_ChIP-ChIP_JURKAT_Human2.36259523
18ELK1_19687146_ChIP-ChIP_HELA_Human2.32664551
19FOXP3_21729870_ChIP-Seq_TREG_Human2.29441176
20IGF1R_20145208_ChIP-Seq_DFB_Human2.15446383
21MYC_18555785_ChIP-Seq_MESCs_Mouse2.02135820
22EWS_26573619_Chip-Seq_HEK293_Human1.93832469
23MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.88948276
24MYC_18940864_ChIP-ChIP_HL60_Human1.87402876
25FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.79713803
26CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.75701964
27PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.68336834
28NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.64565381
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.63674450
30TTF2_22483619_ChIP-Seq_HELA_Human1.60536704
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.58948257
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.56191475
33GABP_19822575_ChIP-Seq_HepG2_Human1.55109701
34NOTCH1_21737748_ChIP-Seq_TLL_Human1.53470742
35HOXB4_20404135_ChIP-ChIP_EML_Mouse1.51274330
36FUS_26573619_Chip-Seq_HEK293_Human1.50342288
37IRF1_19129219_ChIP-ChIP_H3396_Human1.48749975
38FLI1_27457419_Chip-Seq_LIVER_Mouse1.47924846
39EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.46861561
40POU3F2_20337985_ChIP-ChIP_501MEL_Human1.44114540
41DCP1A_22483619_ChIP-Seq_HELA_Human1.39853378
42MYC_18358816_ChIP-ChIP_MESCs_Mouse1.39333840
43TP53_22573176_ChIP-Seq_HFKS_Human1.39010205
44P300_19829295_ChIP-Seq_ESCs_Human1.38267113
45MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.38162576
46PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.37386959
47PADI4_21655091_ChIP-ChIP_MCF-7_Human1.36824745
48ZFP57_27257070_Chip-Seq_ESCs_Mouse1.36622657
49TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.32903874
50E2F4_17652178_ChIP-ChIP_JURKAT_Human1.31793263
51SALL1_21062744_ChIP-ChIP_HESCs_Human1.26130542
52GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.21764885
53CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.19126625
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.18285287
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.17351929
56SOX2_19829295_ChIP-Seq_ESCs_Human1.15779593
57NANOG_19829295_ChIP-Seq_ESCs_Human1.15779593
58E2F1_18555785_ChIP-Seq_MESCs_Mouse1.15462585
59GBX2_23144817_ChIP-Seq_PC3_Human1.15253095
60ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14343042
61BCAT_22108803_ChIP-Seq_LS180_Human1.12669018
62POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11812142
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.11615940
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.10255377
65MYC_19030024_ChIP-ChIP_MESCs_Mouse1.07889172
66CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.07547196
67CBP_20019798_ChIP-Seq_JUKART_Human1.06900392
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.06900392
69PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.06318581
70RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.05946069
71AR_20517297_ChIP-Seq_VCAP_Human1.05698351
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.05454219
73CTBP1_25329375_ChIP-Seq_LNCAP_Human1.04600719
74HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03789282
75THAP11_20581084_ChIP-Seq_MESCs_Mouse1.03255316
76KLF5_20875108_ChIP-Seq_MESCs_Mouse1.02417566
77ER_23166858_ChIP-Seq_MCF-7_Human1.01850362
78FOXA1_27270436_Chip-Seq_PROSTATE_Human1.00944660
79FOXA1_25329375_ChIP-Seq_VCAP_Human1.00944660
80UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.00603753
81EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.00198109
82MYC_19079543_ChIP-ChIP_MESCs_Mouse0.99828421
83SOX2_16153702_ChIP-ChIP_HESCs_Human0.99787555
84TAF15_26573619_Chip-Seq_HEK293_Human0.99423440
85KDM5A_27292631_Chip-Seq_BREAST_Human0.95319979
86ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93210423
87TCF4_22108803_ChIP-Seq_LS180_Human0.92196372
88RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.91980217
89CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.91585953
90HTT_18923047_ChIP-ChIP_STHdh_Human0.89766125
91CTBP2_25329375_ChIP-Seq_LNCAP_Human0.89296974
92ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88861820
93XRN2_22483619_ChIP-Seq_HELA_Human0.88522752
94SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.87107477
95NANOG_20526341_ChIP-Seq_ESCs_Human0.86556540
96ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85759060
97FOXH1_21741376_ChIP-Seq_EPCs_Human0.85520253
98FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.85376562
99GATA3_21878914_ChIP-Seq_MCF-7_Human0.84990260
100AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82515853

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.03083722
2MP0003787_abnormal_imprinting3.25617118
3MP0008877_abnormal_DNA_methylation3.20163412
4MP0008789_abnormal_olfactory_epithelium3.14333758
5MP0005645_abnormal_hypothalamus_physiol2.79903605
6MP0008058_abnormal_DNA_repair2.65498428
7MP0005394_taste/olfaction_phenotype2.56758425
8MP0005499_abnormal_olfactory_system2.56758425
9MP0009379_abnormal_foot_pigmentation2.52571852
10MP0002163_abnormal_gland_morphology2.44832512
11MP0000372_irregular_coat_pigmentation2.44030270
12MP0003121_genomic_imprinting2.22326066
13MP0003880_abnormal_central_pattern2.21279849
14MP0006072_abnormal_retinal_apoptosis2.18701348
15MP0001986_abnormal_taste_sensitivity2.16446941
16MP0003136_yellow_coat_color2.10234835
17MP0002138_abnormal_hepatobiliary_system2.08427255
18MP0003122_maternal_imprinting2.02166188
19MP0003186_abnormal_redox_activity2.00792995
20MP0005646_abnormal_pituitary_gland1.96459351
21MP0005075_abnormal_melanosome_morpholog1.88619356
22MP0005551_abnormal_eye_electrophysiolog1.85935115
23MP0002938_white_spotting1.84127060
24MP0001293_anophthalmia1.83162947
25MP0000631_abnormal_neuroendocrine_gland1.81624902
26MP0002837_dystrophic_cardiac_calcinosis1.81221330
27MP0005084_abnormal_gallbladder_morpholo1.77545539
28MP0004147_increased_porphyrin_level1.77367737
29MP0005379_endocrine/exocrine_gland_phen1.76816734
30MP0003718_maternal_effect1.71395396
31MP0004142_abnormal_muscle_tone1.64543474
32MP0002160_abnormal_reproductive_system1.59086709
33MP0004145_abnormal_muscle_electrophysio1.57630561
34MP0002102_abnormal_ear_morphology1.55687160
35MP0002254_reproductive_system_inflammat1.55033271
36MP0002638_abnormal_pupillary_reflex1.50595036
37MP0001529_abnormal_vocalization1.49409545
38MP0004133_heterotaxia1.47636734
39MP0003011_delayed_dark_adaptation1.44104191
40MP0009697_abnormal_copulation1.43965505
41MP0005174_abnormal_tail_pigmentation1.40858736
42MP0005253_abnormal_eye_physiology1.40159143
43MP0003693_abnormal_embryo_hatching1.37661613
44MP0003123_paternal_imprinting1.33933003
45MP0006036_abnormal_mitochondrial_physio1.33414443
46MP0002233_abnormal_nose_morphology1.32568820
47MP0003890_abnormal_embryonic-extraembry1.32161321
48MP0008872_abnormal_physiological_respon1.31919810
49MP0002210_abnormal_sex_determination1.31799126
50MP0001324_abnormal_eye_pigmentation1.27935178
51MP0005220_abnormal_exocrine_pancreas1.21604837
52MP0006276_abnormal_autonomic_nervous1.20589066
53MP0001968_abnormal_touch/_nociception1.15675962
54MP0002736_abnormal_nociception_after1.13653891
55MP0001188_hyperpigmentation1.13549959
56MP0002095_abnormal_skin_pigmentation1.12743688
57MP0001929_abnormal_gametogenesis1.12726725
58MP0000516_abnormal_urinary_system1.12228765
59MP0005367_renal/urinary_system_phenotyp1.12228765
60MP0005389_reproductive_system_phenotype1.09583970
61MP0000653_abnormal_sex_gland1.08866799
62MP0002751_abnormal_autonomic_nervous1.06662357
63MP0001145_abnormal_male_reproductive1.02984187
64MP0001764_abnormal_homeostasis1.02673085
65MP0005195_abnormal_posterior_eye1.00651841
66MP0001119_abnormal_female_reproductive1.00531968
67MP0001905_abnormal_dopamine_level0.97583720
68MP0000427_abnormal_hair_cycle0.96800905
69MP0002928_abnormal_bile_duct0.96177085
70MP0000049_abnormal_middle_ear0.95589768
71MP0002234_abnormal_pharynx_morphology0.95320404
72MP0000358_abnormal_cell_content/0.95091924
73MP0006035_abnormal_mitochondrial_morpho0.94819437
74MP0003183_abnormal_peptide_metabolism0.92977094
75MP0003646_muscle_fatigue0.90231844
76MP0005410_abnormal_fertilization0.88658086
77MP0001984_abnormal_olfaction0.88173574
78MP0002090_abnormal_vision0.87822772
79MP0002127_abnormal_cardiovascular_syste0.84421586
80MP0001485_abnormal_pinna_reflex0.83183117
81MP0002132_abnormal_respiratory_system0.81750100
82MP0003698_abnormal_male_reproductive0.80517423
83MP0002752_abnormal_somatic_nervous0.80118569
84MP0002693_abnormal_pancreas_physiology0.79164250
85MP0001963_abnormal_hearing_physiology0.78162025
86MP0005391_vision/eye_phenotype0.78105813
87MP0008995_early_reproductive_senescence0.76992897
88MP0001286_abnormal_eye_development0.75263650
89MP0002653_abnormal_ependyma_morphology0.73995922
90MP0002272_abnormal_nervous_system0.72980745
91MP0010094_abnormal_chromosome_stability0.71866267
92MP0004957_abnormal_blastocyst_morpholog0.70954788
93MP0000778_abnormal_nervous_system0.69680202
94MP0003283_abnormal_digestive_organ0.66631805
95MP0002277_abnormal_respiratory_mucosa0.65451102
96MP0000026_abnormal_inner_ear0.64473024
97MP0003252_abnormal_bile_duct0.63905333
98MP0003119_abnormal_digestive_system0.62255526
99MP0001835_abnormal_antigen_presentation0.62220323
100MP0008932_abnormal_embryonic_tissue0.61719319

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.04270656
2Abnormality of cells of the erythroid lineage (HP:0012130)3.76574818
3Reticulocytopenia (HP:0001896)3.69267941
4Acute encephalopathy (HP:0006846)3.53639805
5Abnormal mitochondria in muscle tissue (HP:0008316)3.53383669
6Mitochondrial inheritance (HP:0001427)3.51826468
7Progressive macrocephaly (HP:0004481)3.49050454
8Increased hepatocellular lipid droplets (HP:0006565)3.46768216
9Medial flaring of the eyebrow (HP:0010747)3.44070052
10Increased CSF lactate (HP:0002490)3.31630479
11Renal Fanconi syndrome (HP:0001994)3.25900862
12Macrocytic anemia (HP:0001972)3.12814290
13Lipid accumulation in hepatocytes (HP:0006561)3.11700457
14Methylmalonic acidemia (HP:0002912)3.06206782
15Abnormal number of erythroid precursors (HP:0012131)3.04790451
16Congenital primary aphakia (HP:0007707)2.98265292
17Absent rod-and cone-mediated responses on ERG (HP:0007688)2.94904270
18Gait imbalance (HP:0002141)2.94161617
19Abnormal rod and cone electroretinograms (HP:0008323)2.83737820
20Optic disc pallor (HP:0000543)2.77722229
21Nephrogenic diabetes insipidus (HP:0009806)2.74445162
223-Methylglutaconic aciduria (HP:0003535)2.74380766
23Hepatic necrosis (HP:0002605)2.73361447
24Pancreatic fibrosis (HP:0100732)2.72917659
25Nephronophthisis (HP:0000090)2.71312908
26Hepatocellular necrosis (HP:0001404)2.69008918
27Abnormality of midbrain morphology (HP:0002418)2.68743453
28Molar tooth sign on MRI (HP:0002419)2.68743453
29Pancreatic cysts (HP:0001737)2.68204562
30Stenosis of the external auditory canal (HP:0000402)2.67267716
31Methylmalonic aciduria (HP:0012120)2.64281862
32Abnormality of the labia minora (HP:0012880)2.60396332
33Hyperglycinemia (HP:0002154)2.50791979
34Aplasia/Hypoplasia of the sacrum (HP:0008517)2.45508619
35Abnormality of renal resorption (HP:0011038)2.44474116
36True hermaphroditism (HP:0010459)2.40179738
37Aplasia/Hypoplasia of the spleen (HP:0010451)2.39853191
38Abnormality of the renal cortex (HP:0011035)2.35315576
39Renal cortical cysts (HP:0000803)2.33640965
40Abnormality of the renal medulla (HP:0100957)2.32333341
41Abnormality of urine glucose concentration (HP:0011016)2.32324192
42Glycosuria (HP:0003076)2.32324192
43Cerebral edema (HP:0002181)2.31889552
44Increased intramyocellular lipid droplets (HP:0012240)2.31698482
45Tubular atrophy (HP:0000092)2.28827066
46Colon cancer (HP:0003003)2.27076073
47Neoplasm of the adrenal cortex (HP:0100641)2.25745172
48Exertional dyspnea (HP:0002875)2.24183093
49Pallor (HP:0000980)2.19430983
50Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.18380096
51Tubulointerstitial nephritis (HP:0001970)2.13303869
52Asplenia (HP:0001746)2.13058667
53Lactic acidosis (HP:0003128)2.13039823
54Abnormality of DNA repair (HP:0003254)2.12891912
55Increased serum lactate (HP:0002151)2.12154861
56Genital tract atresia (HP:0001827)2.10654413
57Supernumerary spleens (HP:0009799)2.10385817
58Aplasia/Hypoplasia of the tongue (HP:0010295)2.08942523
59Hypoglycemic seizures (HP:0002173)2.05277806
60Abnormal drinking behavior (HP:0030082)2.04484232
61Polydipsia (HP:0001959)2.04484232
62Respiratory difficulties (HP:0002880)2.03611067
63Intestinal atresia (HP:0011100)2.02958127
64Abnormal pancreas size (HP:0012094)2.02413228
65Median cleft lip (HP:0000161)2.02322896
66Attenuation of retinal blood vessels (HP:0007843)2.01750075
67Vaginal atresia (HP:0000148)2.01346700
68Respiratory failure (HP:0002878)1.97368236
69Decreased testicular size (HP:0008734)1.96655388
70Type 2 muscle fiber atrophy (HP:0003554)1.96436289
71Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.95842593
72Dyschromatopsia (HP:0007641)1.93960656
73Adrenal hypoplasia (HP:0000835)1.93669457
74Aplastic anemia (HP:0001915)1.93625166
75Congenital stationary night blindness (HP:0007642)1.93205826
76Abolished electroretinogram (ERG) (HP:0000550)1.92197171
77Poor coordination (HP:0002370)1.90064243
78Lethargy (HP:0001254)1.88284531
79Sensory axonal neuropathy (HP:0003390)1.87429085
80Abnormality of dicarboxylic acid metabolism (HP:0010995)1.84894441
81Dicarboxylic aciduria (HP:0003215)1.84894441
82Brushfield spots (HP:0001088)1.83799026
83Hyperinsulinemic hypoglycemia (HP:0000825)1.83126335
84Hypoglycemic coma (HP:0001325)1.82561257
85Hypophosphatemic rickets (HP:0004912)1.81001219
86Increased muscle lipid content (HP:0009058)1.80354022
87Constricted visual fields (HP:0001133)1.79073148
88Poor suck (HP:0002033)1.78683744
89Hypokinesia (HP:0002375)1.75620559
90Poikiloderma (HP:0001029)1.74554031
91Depressed nasal ridge (HP:0000457)1.74254940
92Absent thumb (HP:0009777)1.73291473
93Metaphyseal dysplasia (HP:0100255)1.72672072
94Short tibia (HP:0005736)1.70458051
95Multiple enchondromatosis (HP:0005701)1.70288752
96Entropion (HP:0000621)1.69119387
97Anencephaly (HP:0002323)1.68001291
98Tubulointerstitial abnormality (HP:0001969)1.67357895
99Neoplasm of the adrenal gland (HP:0100631)1.66015641
100Decreased electroretinogram (ERG) amplitude (HP:0000654)1.65418953

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK165.67007207
2CDK193.47311714
3MAP3K123.24012409
4NUAK12.85498028
5MAP4K22.71697821
6MST42.71262239
7TIE12.67702266
8BCKDK2.30282936
9PINK12.12272059
10MAP3K92.07568534
11TNIK1.89043421
12GRK11.88629473
13TRIM281.80631853
14ZAK1.63323140
15PASK1.57672891
16BMPR1B1.49849331
17FRK1.47586447
18ARAF1.47046603
19WNK31.46672250
20TEC1.45778341
21FLT31.45634564
22EIF2AK31.36892783
23BRSK21.36510817
24WNK41.28516516
25TLK11.27423020
26DYRK21.27282625
27TRPM71.22098838
28VRK11.21692113
29CCNB11.19725568
30STK391.14271752
31KIT1.00761971
32TGFBR10.99164948
33OXSR10.98700907
34DYRK30.97851159
35STK240.94913935
36MAP3K40.94496709
37CDC70.92134445
38EPHA40.91282161
39CSNK1G10.89056955
40BMPR20.88907736
41EIF2AK10.88866821
42MARK30.86266505
43PRKCQ0.85839418
44CSF1R0.84827746
45CSNK1G30.84052568
46ILK0.83083560
47ADRBK20.82651996
48MAPK130.81058487
49MAP2K70.76386597
50BRAF0.74880918
51RAF10.74512944
52VRK20.74501616
53SCYL20.73239589
54PLK30.71887570
55DMPK0.70910426
56PAK30.69978508
57NME20.65307168
58PLK10.65296980
59PIM20.62021087
60CSNK1A1L0.61821497
61CSNK1G20.61610419
62MATK0.61551629
63PLK40.61131730
64CAMKK20.60818509
65ERBB30.60708492
66BCR0.59294786
67TAOK30.59279850
68BTK0.58799575
69PRKCE0.57761144
70RPS6KB20.56732076
71LRRK20.56500015
72CSNK2A20.56429566
73MAP3K50.56121071
74STK30.54404256
75MUSK0.53823100
76DAPK30.53686362
77NEK10.52847794
78IKBKB0.52153031
79INSRR0.51656590
80AURKB0.51116991
81ATR0.49785640
82AURKA0.49112955
83ADRBK10.48538484
84MYLK0.47345880
85CHEK20.46488275
86RPS6KA50.45440869
87ACVR1B0.44732848
88CSNK2A10.43782712
89MAP4K10.41841475
90ITK0.41771788
91NLK0.39674045
92ATM0.38745418
93PRKACA0.36546941
94CASK0.36084944
95LIMK10.35831508
96MKNK10.34706866
97PLK20.34503096
98ABL20.32850824
99PRKCI0.32237781
100CSNK1E0.31083584

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.90522542
2Protein export_Homo sapiens_hsa030603.52492297
3Oxidative phosphorylation_Homo sapiens_hsa001903.34876844
4Parkinsons disease_Homo sapiens_hsa050122.88056670
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.69000137
6Basal transcription factors_Homo sapiens_hsa030222.57996948
7RNA polymerase_Homo sapiens_hsa030202.48347506
8Regulation of autophagy_Homo sapiens_hsa041402.10889303
9RNA degradation_Homo sapiens_hsa030181.96027877
10Proteasome_Homo sapiens_hsa030501.93313471
11Homologous recombination_Homo sapiens_hsa034401.92611347
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.92012411
13Mismatch repair_Homo sapiens_hsa034301.87741598
14Huntingtons disease_Homo sapiens_hsa050161.87488735
15Non-homologous end-joining_Homo sapiens_hsa034501.85385829
16Propanoate metabolism_Homo sapiens_hsa006401.81281076
17Vitamin B6 metabolism_Homo sapiens_hsa007501.76245634
18Nucleotide excision repair_Homo sapiens_hsa034201.74041335
19Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.66898848
20Fanconi anemia pathway_Homo sapiens_hsa034601.63319120
21Phototransduction_Homo sapiens_hsa047441.61676322
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.60728539
23Asthma_Homo sapiens_hsa053101.56746573
24Alzheimers disease_Homo sapiens_hsa050101.56388801
25Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.54575866
26Base excision repair_Homo sapiens_hsa034101.53867899
27Butanoate metabolism_Homo sapiens_hsa006501.50177093
28Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.46321563
29Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.45616178
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41732029
31Peroxisome_Homo sapiens_hsa041461.40530925
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.39706782
33Fatty acid elongation_Homo sapiens_hsa000621.38124560
34Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.36685736
35Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.36229339
36RNA transport_Homo sapiens_hsa030131.34792700
37Type I diabetes mellitus_Homo sapiens_hsa049401.26899964
38Collecting duct acid secretion_Homo sapiens_hsa049661.22848934
39Allograft rejection_Homo sapiens_hsa053301.21040673
40Purine metabolism_Homo sapiens_hsa002301.20654960
41Intestinal immune network for IgA production_Homo sapiens_hsa046721.20514802
42Pyrimidine metabolism_Homo sapiens_hsa002401.18698811
43Cardiac muscle contraction_Homo sapiens_hsa042601.14978942
44Sulfur metabolism_Homo sapiens_hsa009201.09753634
45Steroid biosynthesis_Homo sapiens_hsa001001.03868381
46Caffeine metabolism_Homo sapiens_hsa002321.01256042
47Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.96368110
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.95710284
49Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.95308028
50Cysteine and methionine metabolism_Homo sapiens_hsa002700.87902815
51Autoimmune thyroid disease_Homo sapiens_hsa053200.87180511
52Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.81947556
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.79866611
54DNA replication_Homo sapiens_hsa030300.77788514
55Olfactory transduction_Homo sapiens_hsa047400.77741621
56p53 signaling pathway_Homo sapiens_hsa041150.76387245
57Metabolic pathways_Homo sapiens_hsa011000.73881736
58Spliceosome_Homo sapiens_hsa030400.73752446
59Glutathione metabolism_Homo sapiens_hsa004800.67908685
60Rheumatoid arthritis_Homo sapiens_hsa053230.67356276
61Graft-versus-host disease_Homo sapiens_hsa053320.64397029
62Systemic lupus erythematosus_Homo sapiens_hsa053220.59422005
63Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.58090020
64Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.57183004
65Linoleic acid metabolism_Homo sapiens_hsa005910.56823008
66alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.49241128
67Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.47373238
68Retinol metabolism_Homo sapiens_hsa008300.44550489
69Sulfur relay system_Homo sapiens_hsa041220.43834877
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.43531182
71Hedgehog signaling pathway_Homo sapiens_hsa043400.43171007
72Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42872974
73Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.41549032
74Tryptophan metabolism_Homo sapiens_hsa003800.39278651
75Folate biosynthesis_Homo sapiens_hsa007900.38570641
76Alcoholism_Homo sapiens_hsa050340.36290731
77Nitrogen metabolism_Homo sapiens_hsa009100.33866207
78beta-Alanine metabolism_Homo sapiens_hsa004100.33417751
79Drug metabolism - other enzymes_Homo sapiens_hsa009830.32174138
80Chemical carcinogenesis_Homo sapiens_hsa052040.31817151
81Pyruvate metabolism_Homo sapiens_hsa006200.31555090
82Arachidonic acid metabolism_Homo sapiens_hsa005900.31504445
83Fatty acid degradation_Homo sapiens_hsa000710.31000402
84Fatty acid metabolism_Homo sapiens_hsa012120.30968994
85One carbon pool by folate_Homo sapiens_hsa006700.30533542
86Primary immunodeficiency_Homo sapiens_hsa053400.29947110
87Pentose and glucuronate interconversions_Homo sapiens_hsa000400.27620115
88N-Glycan biosynthesis_Homo sapiens_hsa005100.27385998
89Steroid hormone biosynthesis_Homo sapiens_hsa001400.27177720
90Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.27026565
91Oocyte meiosis_Homo sapiens_hsa041140.25242175
92Ether lipid metabolism_Homo sapiens_hsa005650.24249319
93Legionellosis_Homo sapiens_hsa051340.24203061
942-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.23720130
95Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.22816967
96Arginine and proline metabolism_Homo sapiens_hsa003300.19512409
97mRNA surveillance pathway_Homo sapiens_hsa030150.19186591
98Epstein-Barr virus infection_Homo sapiens_hsa051690.17559475
99Cell cycle_Homo sapiens_hsa041100.17178152
100Viral myocarditis_Homo sapiens_hsa054160.17001841

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