Rank | Gene Set | Z-score |
---|---|---|
1 | * SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 9.75226489 |
2 | * cotranslational protein targeting to membrane (GO:0006613) | 9.62897532 |
3 | * protein targeting to ER (GO:0045047) | 9.59412921 |
4 | * translational elongation (GO:0006414) | 9.48131619 |
5 | * establishment of protein localization to endoplasmic reticulum (GO:0072599) | 9.18259532 |
6 | * protein localization to endoplasmic reticulum (GO:0070972) | 9.01039501 |
7 | * viral life cycle (GO:0019058) | 8.85439691 |
8 | * cellular protein complex disassembly (GO:0043624) | 8.78038123 |
9 | * nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 8.64029790 |
10 | maturation of SSU-rRNA (GO:0030490) | 8.44495775 |
11 | * translational initiation (GO:0006413) | 7.93322139 |
12 | * protein complex disassembly (GO:0043241) | 7.55797248 |
13 | ribosomal large subunit biogenesis (GO:0042273) | 7.24273445 |
14 | * macromolecular complex disassembly (GO:0032984) | 7.04207666 |
15 | * protein targeting to membrane (GO:0006612) | 6.43629387 |
16 | * nuclear-transcribed mRNA catabolic process (GO:0000956) | 5.97788997 |
17 | * mRNA catabolic process (GO:0006402) | 5.67936848 |
18 | * translation (GO:0006412) | 5.63546743 |
19 | * RNA catabolic process (GO:0006401) | 5.15762512 |
20 | ribonucleoprotein complex biogenesis (GO:0022613) | 5.10119182 |
21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.76479862 |
22 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.59536348 |
23 | ATP synthesis coupled proton transport (GO:0015986) | 4.59536348 |
24 | * establishment of protein localization to membrane (GO:0090150) | 4.35207068 |
25 | ATP biosynthetic process (GO:0006754) | 4.24127282 |
26 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.23672642 |
27 | DNA deamination (GO:0045006) | 4.10020226 |
28 | hydrogen ion transmembrane transport (GO:1902600) | 4.02320545 |
29 | cellular component biogenesis (GO:0044085) | 4.01055567 |
30 | * protein targeting (GO:0006605) | 3.97647885 |
31 | sequestering of actin monomers (GO:0042989) | 3.97277581 |
32 | rRNA processing (GO:0006364) | 3.90254215 |
33 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.82328210 |
34 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.81579426 |
35 | * establishment of protein localization to organelle (GO:0072594) | 3.80437994 |
36 | rRNA metabolic process (GO:0016072) | 3.73814422 |
37 | proton transport (GO:0015992) | 3.61668969 |
38 | formation of translation preinitiation complex (GO:0001731) | 3.57944330 |
39 | hydrogen transport (GO:0006818) | 3.55088685 |
40 | inner mitochondrial membrane organization (GO:0007007) | 3.42842107 |
41 | * protein localization to membrane (GO:0072657) | 3.39931989 |
42 | oxidative phosphorylation (GO:0006119) | 3.30884458 |
43 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.30718426 |
44 | protein-cofactor linkage (GO:0018065) | 3.21751547 |
45 | ncRNA 3-end processing (GO:0043628) | 3.19949597 |
46 | establishment of integrated proviral latency (GO:0075713) | 3.14608663 |
47 | termination of RNA polymerase III transcription (GO:0006386) | 3.14217432 |
48 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.14217432 |
49 | GTP biosynthetic process (GO:0006183) | 3.14110518 |
50 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.13604873 |
51 | intracellular protein transmembrane import (GO:0044743) | 3.09679558 |
52 | proteasome assembly (GO:0043248) | 2.97249375 |
53 | respiratory electron transport chain (GO:0022904) | 2.96075933 |
54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.95921047 |
55 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.95921047 |
56 | UTP biosynthetic process (GO:0006228) | 2.93586780 |
57 | electron transport chain (GO:0022900) | 2.90960015 |
58 | nucleoside triphosphate biosynthetic process (GO:0009142) | 2.87006217 |
59 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.85407780 |
60 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.84621673 |
61 | cytochrome complex assembly (GO:0017004) | 2.84505791 |
62 | establishment of protein localization to mitochondrion (GO:0072655) | 2.83291019 |
63 | protein targeting to mitochondrion (GO:0006626) | 2.83192262 |
64 | respiratory chain complex IV assembly (GO:0008535) | 2.82866045 |
65 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.82086243 |
66 | regulation of mitochondrial translation (GO:0070129) | 2.81952723 |
67 | * cellular component disassembly (GO:0022411) | 2.81119214 |
68 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.79938993 |
69 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.79938993 |
70 | establishment of viral latency (GO:0019043) | 2.77633739 |
71 | aerobic respiration (GO:0009060) | 2.75706448 |
72 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.75591608 |
73 | spliceosomal complex assembly (GO:0000245) | 2.75535542 |
74 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.74672896 |
75 | rRNA modification (GO:0000154) | 2.74075131 |
76 | * protein localization to organelle (GO:0033365) | 2.74058239 |
77 | mitochondrial transport (GO:0006839) | 2.72269794 |
78 | spliceosomal snRNP assembly (GO:0000387) | 2.72146789 |
79 | protein localization to mitochondrion (GO:0070585) | 2.71596081 |
80 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.69613042 |
81 | neuron fate determination (GO:0048664) | 2.68426401 |
82 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.66661068 |
83 | chromatin remodeling at centromere (GO:0031055) | 2.65234677 |
84 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.64187749 |
85 | pseudouridine synthesis (GO:0001522) | 2.62385558 |
86 | organelle disassembly (GO:1903008) | 2.62066557 |
87 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.60930677 |
88 | telomere maintenance via semi-conservative replication (GO:0032201) | 2.60545347 |
89 | DNA damage response, detection of DNA damage (GO:0042769) | 2.57982912 |
90 | chaperone-mediated protein transport (GO:0072321) | 2.57511424 |
91 | negative regulation of ligase activity (GO:0051352) | 2.57012230 |
92 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.57012230 |
93 | CENP-A containing nucleosome assembly (GO:0034080) | 2.55993007 |
94 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.55213185 |
95 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.55213185 |
96 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.54153969 |
97 | UTP metabolic process (GO:0046051) | 2.53980211 |
98 | ncRNA processing (GO:0034470) | 2.52618522 |
99 | negative regulation of RNA splicing (GO:0033119) | 2.52117935 |
100 | CTP biosynthetic process (GO:0006241) | 2.50581863 |
101 | CTP metabolic process (GO:0046036) | 2.50581863 |
102 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.49893712 |
103 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.49893712 |
104 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.49893712 |
105 | DNA strand elongation involved in DNA replication (GO:0006271) | 2.49182722 |
106 | otic vesicle formation (GO:0030916) | 2.47653909 |
107 | * gene expression (GO:0010467) | 2.47312614 |
108 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.46807046 |
109 | NADH dehydrogenase complex assembly (GO:0010257) | 2.46807046 |
110 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.46807046 |
111 | termination of RNA polymerase I transcription (GO:0006363) | 2.45030095 |
112 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.44753034 |
113 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.44753034 |
114 | protein neddylation (GO:0045116) | 2.42663755 |
115 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 2.42506586 |
116 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.42051016 |
117 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.41577502 |
118 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.41005103 |
119 | positive regulation of respiratory burst (GO:0060267) | 2.40206485 |
120 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.39766366 |
121 | behavioral response to nicotine (GO:0035095) | 2.39349670 |
122 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.39098825 |
123 | epithelial cilium movement (GO:0003351) | 2.35744783 |
124 | histone mRNA metabolic process (GO:0008334) | 2.35630364 |
125 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.34321837 |
126 | DNA strand elongation (GO:0022616) | 2.34245341 |
127 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.33460686 |
128 | platelet dense granule organization (GO:0060155) | 2.32440137 |
129 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.31335371 |
130 | 7-methylguanosine mRNA capping (GO:0006370) | 2.29842758 |
131 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.28547573 |
132 | protein complex biogenesis (GO:0070271) | 2.28350719 |
133 | RNA capping (GO:0036260) | 2.28321841 |
134 | 7-methylguanosine RNA capping (GO:0009452) | 2.28321841 |
135 | * viral transcription (GO:0019083) | 11.9434270 |
136 | * translational termination (GO:0006415) | 11.4102874 |
137 | ribosomal small subunit biogenesis (GO:0042274) | 11.0810957 |
138 | ribosomal small subunit assembly (GO:0000028) | 10.6739945 |
Rank | Gene Set | Z-score |
---|---|---|
1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 6.95822914 |
2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.81537747 |
3 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.88918341 |
4 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.84837454 |
5 | * EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.75072287 |
6 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.61256527 |
7 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.60945439 |
8 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.48070302 |
9 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.33725622 |
10 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.28123518 |
11 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.27809356 |
12 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.03491113 |
13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.87514830 |
14 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.85763252 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.82503892 |
16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.80700612 |
17 | * CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.78203192 |
18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.74510281 |
19 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.70286114 |
20 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.55947265 |
21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.52215983 |
22 | * TTF2_22483619_ChIP-Seq_HELA_Human | 2.51511283 |
23 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.50820539 |
24 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.35484512 |
25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.34312514 |
26 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.26043918 |
27 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.19132495 |
28 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.14549479 |
29 | * FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04694349 |
30 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.03474566 |
31 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.03055774 |
32 | * CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 2.00907667 |
33 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.96175973 |
34 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88208751 |
35 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83920611 |
36 | * ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.80088802 |
37 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.77335716 |
38 | FUS_26573619_Chip-Seq_HEK293_Human | 1.75990032 |
39 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.73091091 |
40 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.71843940 |
41 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.67506087 |
42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.67483068 |
43 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.66618049 |
44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.66393475 |
45 | EWS_26573619_Chip-Seq_HEK293_Human | 1.64876584 |
46 | VDR_22108803_ChIP-Seq_LS180_Human | 1.60902357 |
47 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.57945633 |
48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54941809 |
49 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.51276243 |
50 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.49655777 |
51 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.49161405 |
52 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.46343756 |
53 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.45845135 |
54 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.45522536 |
55 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.44954742 |
56 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.44737120 |
57 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.42491286 |
58 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.42329736 |
59 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.39936354 |
60 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.39652421 |
61 | * MYC_18940864_ChIP-ChIP_HL60_Human | 1.39120450 |
62 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.34790962 |
63 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.34680663 |
64 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.34650553 |
65 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.33364045 |
66 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.32703399 |
67 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.32366461 |
68 | * YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.30554235 |
69 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.27371650 |
70 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.26756800 |
71 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.26278953 |
72 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.24165528 |
73 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.19926832 |
74 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.19712504 |
75 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.18326695 |
76 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.18257398 |
77 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.17061412 |
78 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.15003981 |
79 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.09652311 |
80 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.09247869 |
81 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.09039255 |
82 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.08283406 |
83 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.08199938 |
84 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.06074157 |
85 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.05384070 |
86 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04931112 |
87 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03926704 |
88 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.03761046 |
89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.03644491 |
90 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.03091665 |
91 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.02930821 |
92 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.02778021 |
93 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.02114223 |
94 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 1.01642444 |
95 | MYC_22102868_ChIP-Seq_BL_Human | 1.01503596 |
96 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.00706777 |
97 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.00678031 |
98 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.97780356 |
99 | MAF_26560356_Chip-Seq_TH2_Human | 0.97182240 |
100 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96891864 |
101 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.95718744 |
102 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.93168331 |
103 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90865180 |
104 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.88188453 |
105 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.87993501 |
106 | * HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.86943057 |
107 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.86398486 |
108 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.85790381 |
109 | VDR_24763502_ChIP-Seq_THP-1_Human | 0.85240718 |
110 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.84984442 |
111 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.84970352 |
112 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.84302760 |
113 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.83994772 |
114 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.83780700 |
115 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.82846885 |
116 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.82272100 |
117 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.82062895 |
118 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.81821936 |
119 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.80591359 |
120 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.80472519 |
121 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.80395244 |
122 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.80395244 |
123 | UTX_26944678_Chip-Seq_JUKART_Human | 0.80288157 |
124 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.79776120 |
125 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.79042410 |
126 | AR_20517297_ChIP-Seq_VCAP_Human | 0.78794383 |
127 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.77955571 |
128 | MAF_26560356_Chip-Seq_TH1_Human | 0.77408379 |
129 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.77054060 |
130 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.77019219 |
131 | MYB_26560356_Chip-Seq_TH2_Human | 0.75741969 |
132 | P300_19829295_ChIP-Seq_ESCs_Human | 0.73808238 |
133 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.72151356 |
134 | * IRF1_19129219_ChIP-ChIP_H3396_Human | 0.71937088 |
135 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.71741390 |
136 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.71396694 |
137 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.71307213 |
138 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.70933213 |
139 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.70809295 |
140 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.70519038 |
141 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.68201231 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0009379_abnormal_foot_pigmentation | 7.43978483 |
2 | MP0004381_abnormal_hair_follicle | 2.97873604 |
3 | MP0000566_synostosis | 2.69457332 |
4 | MP0003693_abnormal_embryo_hatching | 2.65323084 |
5 | MP0010030_abnormal_orbit_morphology | 2.62490708 |
6 | MP0005174_abnormal_tail_pigmentation | 2.30463859 |
7 | MP0004957_abnormal_blastocyst_morpholog | 2.27366354 |
8 | MP0003136_yellow_coat_color | 2.26758864 |
9 | MP0006072_abnormal_retinal_apoptosis | 2.24911837 |
10 | MP0001835_abnormal_antigen_presentation | 2.18536081 |
11 | MP0003763_abnormal_thymus_physiology | 2.13105995 |
12 | MP0003011_delayed_dark_adaptation | 2.09311531 |
13 | MP0004142_abnormal_muscle_tone | 1.98377926 |
14 | MP0009333_abnormal_splenocyte_physiolog | 1.94512008 |
15 | MP0005671_abnormal_response_to | 1.94135741 |
16 | MP0008057_abnormal_DNA_replication | 1.91302481 |
17 | MP0000685_abnormal_immune_system | 1.89075198 |
18 | MP0002148_abnormal_hypersensitivity_rea | 1.89060875 |
19 | MP0003880_abnormal_central_pattern | 1.88282577 |
20 | MP0002396_abnormal_hematopoietic_system | 1.86693663 |
21 | MP0002166_altered_tumor_susceptibility | 1.83871383 |
22 | MP0001293_anophthalmia | 1.81168366 |
23 | MP0001800_abnormal_humoral_immune | 1.80929126 |
24 | MP0002132_abnormal_respiratory_system | 1.80826258 |
25 | MP0002796_impaired_skin_barrier | 1.79880603 |
26 | MP0009785_altered_susceptibility_to | 1.79755279 |
27 | MP0005409_darkened_coat_color | 1.74480277 |
28 | MP0000490_abnormal_crypts_of | 1.71889675 |
29 | MP0003806_abnormal_nucleotide_metabolis | 1.69293183 |
30 | MP0005075_abnormal_melanosome_morpholog | 1.68388086 |
31 | MP0002653_abnormal_ependyma_morphology | 1.67311030 |
32 | MP0005000_abnormal_immune_tolerance | 1.64673978 |
33 | MP0005025_abnormal_response_to | 1.64034373 |
34 | MP0001853_heart_inflammation | 1.61242383 |
35 | MP0000465_gastrointestinal_hemorrhage | 1.58684831 |
36 | MP0003724_increased_susceptibility_to | 1.57374290 |
37 | MP0002420_abnormal_adaptive_immunity | 1.57121031 |
38 | MP0003283_abnormal_digestive_organ | 1.57085903 |
39 | MP0003077_abnormal_cell_cycle | 1.56743972 |
40 | MP0002938_white_spotting | 1.55926040 |
41 | MP0002095_abnormal_skin_pigmentation | 1.55193522 |
42 | MP0002723_abnormal_immune_serum | 1.55049437 |
43 | MP0002452_abnormal_antigen_presenting | 1.54384674 |
44 | MP0001819_abnormal_immune_cell | 1.53960749 |
45 | MP0000631_abnormal_neuroendocrine_gland | 1.53130367 |
46 | MP0002009_preneoplasia | 1.52537874 |
47 | MP0003941_abnormal_skin_development | 1.52126879 |
48 | MP0002398_abnormal_bone_marrow | 1.51783197 |
49 | MP0003786_premature_aging | 1.51079229 |
50 | MP0005084_abnormal_gallbladder_morpholo | 1.47808517 |
51 | MP0002006_tumorigenesis | 1.46573680 |
52 | MP0003436_decreased_susceptibility_to | 1.44676358 |
53 | MP0002163_abnormal_gland_morphology | 1.44495427 |
54 | MP0001485_abnormal_pinna_reflex | 1.44110297 |
55 | MP0010094_abnormal_chromosome_stability | 1.43807109 |
56 | MP0002722_abnormal_immune_system | 1.39176638 |
57 | MP0005501_abnormal_skin_physiology | 1.38558061 |
58 | MP0000372_irregular_coat_pigmentation | 1.37230440 |
59 | MP0002277_abnormal_respiratory_mucosa | 1.37039886 |
60 | MP0002102_abnormal_ear_morphology | 1.36998797 |
61 | MP0002405_respiratory_system_inflammati | 1.36362072 |
62 | MP0006054_spinal_hemorrhage | 1.35642590 |
63 | MP0001790_abnormal_immune_system | 1.34316133 |
64 | MP0005387_immune_system_phenotype | 1.34316133 |
65 | MP0000716_abnormal_immune_system | 1.33063823 |
66 | MP0003315_abnormal_perineum_morphology | 1.29616223 |
67 | MP0000703_abnormal_thymus_morphology | 1.29331223 |
68 | MP0008995_early_reproductive_senescence | 1.29132715 |
69 | MP0001873_stomach_inflammation | 1.29080580 |
70 | MP0005423_abnormal_somatic_nervous | 1.28631421 |
71 | MP0008877_abnormal_DNA_methylation | 1.28025316 |
72 | MP0008932_abnormal_embryonic_tissue | 1.25932439 |
73 | MP0000689_abnormal_spleen_morphology | 1.25827095 |
74 | MP0002429_abnormal_blood_cell | 1.23803946 |
75 | MP0004133_heterotaxia | 1.23802336 |
76 | MP0000383_abnormal_hair_follicle | 1.23776960 |
77 | MP0005551_abnormal_eye_electrophysiolog | 1.21503530 |
78 | MP0005499_abnormal_olfactory_system | 1.20317697 |
79 | MP0005394_taste/olfaction_phenotype | 1.20317697 |
80 | MP0001286_abnormal_eye_development | 1.19316218 |
81 | MP0010155_abnormal_intestine_physiology | 1.19107346 |
82 | MP0003866_abnormal_defecation | 1.18687365 |
83 | MP0004742_abnormal_vestibular_system | 1.17568857 |
84 | MP0005253_abnormal_eye_physiology | 1.15866067 |
85 | MP0000026_abnormal_inner_ear | 1.15328619 |
86 | MP0001216_abnormal_epidermal_layer | 1.14600485 |
87 | MP0004808_abnormal_hematopoietic_stem | 1.13765244 |
88 | MP0002638_abnormal_pupillary_reflex | 1.12970320 |
89 | MP0008058_abnormal_DNA_repair | 1.11029194 |
90 | MP0002098_abnormal_vibrissa_morphology | 1.09983976 |
91 | MP0003111_abnormal_nucleus_morphology | 1.07995355 |
92 | MP0006036_abnormal_mitochondrial_physio | 1.07293570 |
93 | MP0002234_abnormal_pharynx_morphology | 1.06095068 |
94 | MP0001346_abnormal_lacrimal_gland | 1.05776379 |
95 | MP0004885_abnormal_endolymph | 1.05558850 |
96 | MP0006276_abnormal_autonomic_nervous | 1.04279802 |
97 | MP0002822_catalepsy | 1.03010258 |
98 | MP0008007_abnormal_cellular_replicative | 1.02773973 |
99 | MP0003890_abnormal_embryonic-extraembry | 1.00525720 |
100 | MP0002160_abnormal_reproductive_system | 1.00181918 |
101 | MP0001984_abnormal_olfaction | 0.98175965 |
102 | MP0004145_abnormal_muscle_electrophysio | 0.97707864 |
103 | MP0003878_abnormal_ear_physiology | 0.97130176 |
104 | MP0005377_hearing/vestibular/ear_phenot | 0.97130176 |
105 | MP0002060_abnormal_skin_morphology | 0.96020405 |
106 | MP0000778_abnormal_nervous_system | 0.95945638 |
107 | MP0005397_hematopoietic_system_phenotyp | 0.95894027 |
108 | MP0001545_abnormal_hematopoietic_system | 0.95894027 |
109 | MP0005645_abnormal_hypothalamus_physiol | 0.95662416 |
110 | MP0001727_abnormal_embryo_implantation | 0.95635799 |
111 | MP0005195_abnormal_posterior_eye | 0.94842171 |
112 | MP0002419_abnormal_innate_immunity | 0.94405226 |
113 | MP0008789_abnormal_olfactory_epithelium | 0.92965210 |
114 | MP0002736_abnormal_nociception_after | 0.92443183 |
115 | MP0004947_skin_inflammation | 0.91543013 |
116 | MP0003938_abnormal_ear_development | 0.91090837 |
117 | MP0003121_genomic_imprinting | 0.90891109 |
118 | MP0000858_altered_metastatic_potential | 0.90478073 |
119 | MP0005646_abnormal_pituitary_gland | 0.90418701 |
120 | MP0003787_abnormal_imprinting | 0.90329955 |
121 | MP0005379_endocrine/exocrine_gland_phen | 0.89823343 |
122 | MP0005408_hypopigmentation | 0.89448522 |
123 | MP0005464_abnormal_platelet_physiology | 0.89183896 |
124 | MP0008875_abnormal_xenobiotic_pharmacok | 0.87687591 |
125 | MP0002019_abnormal_tumor_incidence | 0.87441715 |
126 | MP0002254_reproductive_system_inflammat | 0.87227977 |
127 | MP0002752_abnormal_somatic_nervous | 0.86567543 |
128 | MP0005389_reproductive_system_phenotype | 0.86402337 |
129 | MP0002282_abnormal_trachea_morphology | 0.85951305 |
130 | MP0008872_abnormal_physiological_respon | 0.85754265 |
131 | MP0001986_abnormal_taste_sensitivity | 0.85553710 |
132 | MP0010771_integument_phenotype | 0.85509666 |
133 | MP0001851_eye_inflammation | 0.85296218 |
134 | MP0002210_abnormal_sex_determination | 0.85290929 |
135 | MP0002928_abnormal_bile_duct | 0.85103819 |
136 | MP0006292_abnormal_olfactory_placode | 0.84876292 |
137 | MP0001905_abnormal_dopamine_level | 0.84868431 |
138 | MP0005391_vision/eye_phenotype | 0.83872437 |
139 | MP0001845_abnormal_inflammatory_respons | 0.83650102 |
140 | MP0002272_abnormal_nervous_system | 0.83465472 |
141 | MP0002751_abnormal_autonomic_nervous | 0.83452872 |
142 | MP0002933_joint_inflammation | 0.82719221 |
143 | MP0001968_abnormal_touch/_nociception | 0.81484965 |
144 | MP0000049_abnormal_middle_ear | 0.80924665 |
145 | MP0001529_abnormal_vocalization | 0.79591945 |
146 | MP0008961_abnormal_basal_metabolism | 0.79565387 |
147 | MP0009745_abnormal_behavioral_response | 0.78146499 |
148 | MP0009931_abnormal_skin_appearance | 0.77662509 |
149 | MP0003567_abnormal_fetal_cardiomyocyte | 0.77002408 |
150 | MP0003718_maternal_effect | 0.76496178 |
151 | MP0001919_abnormal_reproductive_system | 0.75931401 |
152 | MP0006035_abnormal_mitochondrial_morpho | 0.75509455 |
153 | MP0000377_abnormal_hair_follicle | 0.75000425 |
154 | MP0001324_abnormal_eye_pigmentation | 0.74914721 |
155 | MP0002233_abnormal_nose_morphology | 0.74780779 |
156 | MP0000762_abnormal_tongue_morphology | 0.74488285 |
157 | MP0003186_abnormal_redox_activity | 0.74328532 |
158 | MP0002697_abnormal_eye_size | 0.73850926 |
159 | MP0010386_abnormal_urinary_bladder | 0.73526035 |
160 | MP0002837_dystrophic_cardiac_calcinosis | 0.73082212 |
161 | MP0003937_abnormal_limbs/digits/tail_de | 0.72806692 |
162 | MP0001764_abnormal_homeostasis | 0.71721237 |
163 | MP0001963_abnormal_hearing_physiology | 0.70160643 |
164 | MP0009250_abnormal_appendicular_skeleto | 0.69532572 |
165 | MP0004147_increased_porphyrin_level | 0.67309188 |
166 | MP0002557_abnormal_social/conspecific_i | 0.66968371 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormal number of erythroid precursors (HP:0012131) | 9.54177318 |
2 | Reticulocytopenia (HP:0001896) | 8.72439993 |
3 | Macrocytic anemia (HP:0001972) | 6.97785743 |
4 | Pallor (HP:0000980) | 6.49081413 |
5 | Increased hepatocellular lipid droplets (HP:0006565) | 3.83572416 |
6 | Acute necrotizing encephalopathy (HP:0006965) | 3.64872042 |
7 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 3.58077993 |
8 | Mitochondrial inheritance (HP:0001427) | 3.53018738 |
9 | Congenital, generalized hypertrichosis (HP:0004540) | 3.45476908 |
10 | Thrombocytosis (HP:0001894) | 3.32840383 |
11 | Abnormal hemoglobin (HP:0011902) | 3.32250577 |
12 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.26631057 |
13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.24899691 |
14 | Renal Fanconi syndrome (HP:0001994) | 3.20474774 |
15 | Exertional dyspnea (HP:0002875) | 3.17959615 |
16 | Abnormality of secondary sexual hair (HP:0009888) | 3.16153053 |
17 | Abnormality of the axillary hair (HP:0100134) | 3.16153053 |
18 | Septo-optic dysplasia (HP:0100842) | 3.13562325 |
19 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.13413778 |
20 | Stenosis of the external auditory canal (HP:0000402) | 3.07702810 |
21 | Progressive macrocephaly (HP:0004481) | 2.97354765 |
22 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.91204578 |
23 | Depressed nasal ridge (HP:0000457) | 2.88988098 |
24 | 3-Methylglutaconic aciduria (HP:0003535) | 2.87920852 |
25 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.87154656 |
26 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.87154656 |
27 | Parakeratosis (HP:0001036) | 2.87005106 |
28 | Aplastic anemia (HP:0001915) | 2.85245021 |
29 | Hepatocellular necrosis (HP:0001404) | 2.84718196 |
30 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.82329548 |
31 | Pancreatic cysts (HP:0001737) | 2.81297324 |
32 | Increased CSF lactate (HP:0002490) | 2.77529650 |
33 | Abnormality of reticulocytes (HP:0004312) | 2.75756565 |
34 | 11 pairs of ribs (HP:0000878) | 2.75502084 |
35 | Molar tooth sign on MRI (HP:0002419) | 2.72222336 |
36 | Abnormality of midbrain morphology (HP:0002418) | 2.72222336 |
37 | Migraine (HP:0002076) | 2.69479435 |
38 | Acute encephalopathy (HP:0006846) | 2.68758706 |
39 | Pancreatic fibrosis (HP:0100732) | 2.68353140 |
40 | Respiratory difficulties (HP:0002880) | 2.65025510 |
41 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.64697590 |
42 | IgM deficiency (HP:0002850) | 2.63676797 |
43 | Increased intramyocellular lipid droplets (HP:0012240) | 2.59767901 |
44 | True hermaphroditism (HP:0010459) | 2.59646113 |
45 | Nephronophthisis (HP:0000090) | 2.52863834 |
46 | Absent thumb (HP:0009777) | 2.51929394 |
47 | Chronic otitis media (HP:0000389) | 2.50357866 |
48 | Woolly hair (HP:0002224) | 2.47483207 |
49 | Colon cancer (HP:0003003) | 2.43632353 |
50 | Glycosuria (HP:0003076) | 2.31631886 |
51 | Abnormality of urine glucose concentration (HP:0011016) | 2.31631886 |
52 | Thick lower lip vermilion (HP:0000179) | 2.28494233 |
53 | Hyperphosphaturia (HP:0003109) | 2.27812262 |
54 | Medial flaring of the eyebrow (HP:0010747) | 2.26722860 |
55 | Asplenia (HP:0001746) | 2.25856117 |
56 | Hepatic necrosis (HP:0002605) | 2.24206078 |
57 | Concave nail (HP:0001598) | 2.20693497 |
58 | Abnormality of the parietal bone (HP:0002696) | 2.18642376 |
59 | Petechiae (HP:0000967) | 2.18271425 |
60 | Partial duplication of thumb phalanx (HP:0009944) | 2.15836066 |
61 | Absent septum pellucidum (HP:0001331) | 2.13823064 |
62 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.13201404 |
63 | Trismus (HP:0000211) | 2.10569061 |
64 | Rib fusion (HP:0000902) | 2.09469937 |
65 | Increased muscle lipid content (HP:0009058) | 2.05391150 |
66 | Type I transferrin isoform profile (HP:0003642) | 2.04472763 |
67 | Hypoplasia of the radius (HP:0002984) | 2.03859203 |
68 | Exercise intolerance (HP:0003546) | 2.03724126 |
69 | Methylmalonic acidemia (HP:0002912) | 2.02911467 |
70 | Fragile nails (HP:0001808) | 2.02172210 |
71 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.01285506 |
72 | Abnormality of cells of the erythroid lineage (HP:0012130) | 10.8718346 |
73 | Sclerocornea (HP:0000647) | 1.99008104 |
74 | Partial duplication of the phalanx of hand (HP:0009999) | 1.97092219 |
75 | Myokymia (HP:0002411) | 1.96716834 |
76 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.96229813 |
77 | Triphalangeal thumb (HP:0001199) | 1.95937202 |
78 | Abnormality of the renal medulla (HP:0100957) | 1.95486731 |
79 | Recurrent bronchitis (HP:0002837) | 1.92945627 |
80 | Hypoproteinemia (HP:0003075) | 1.92039626 |
81 | Multiple enchondromatosis (HP:0005701) | 1.89909328 |
82 | Panhypogammaglobulinemia (HP:0003139) | 1.88933509 |
83 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.87944118 |
84 | Glossoptosis (HP:0000162) | 1.87806147 |
85 | Hypotrichosis (HP:0001006) | 1.87761045 |
86 | Oral leukoplakia (HP:0002745) | 1.87323328 |
87 | Lethargy (HP:0001254) | 1.86272346 |
88 | Maternal diabetes (HP:0009800) | 1.85322379 |
89 | Esophageal atresia (HP:0002032) | 1.84887595 |
90 | Abnormality of placental membranes (HP:0011409) | 1.84042918 |
91 | Amniotic constriction ring (HP:0009775) | 1.84042918 |
92 | Sparse eyelashes (HP:0000653) | 1.83910863 |
93 | Rhinitis (HP:0012384) | 1.83875621 |
94 | Increased serum lactate (HP:0002151) | 1.82501452 |
95 | Abnormal ciliary motility (HP:0012262) | 1.82000485 |
96 | Abnormality of renal resorption (HP:0011038) | 1.81594690 |
97 | Respiratory failure (HP:0002878) | 1.81163211 |
98 | Chronic sinusitis (HP:0011109) | 1.81135564 |
99 | Bilateral microphthalmos (HP:0007633) | 1.80652636 |
100 | Congenital primary aphakia (HP:0007707) | 1.79224718 |
101 | Optic disc pallor (HP:0000543) | 1.78688353 |
102 | Abnormality of the septum pellucidum (HP:0007375) | 1.77632869 |
103 | Cleft eyelid (HP:0000625) | 1.77446997 |
104 | Gait imbalance (HP:0002141) | 1.77430628 |
105 | Abnormality of the labia minora (HP:0012880) | 1.76617014 |
106 | Aplasia cutis congenita (HP:0001057) | 1.75541198 |
107 | Hypoplasia of the pons (HP:0012110) | 1.74262338 |
108 | Abnormality of the pons (HP:0007361) | 1.73068952 |
109 | Anophthalmia (HP:0000528) | 1.72884809 |
110 | Abnormal urine phosphate concentration (HP:0012599) | 1.71649778 |
111 | Male pseudohermaphroditism (HP:0000037) | 1.71496655 |
112 | Congenital stationary night blindness (HP:0007642) | 1.71271710 |
113 | Erythema (HP:0010783) | 1.71061425 |
114 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.68005150 |
115 | Optic nerve hypoplasia (HP:0000609) | 1.67281177 |
116 | Muscle fiber atrophy (HP:0100295) | 1.67273261 |
117 | Rough bone trabeculation (HP:0100670) | 1.67217644 |
118 | Methylmalonic aciduria (HP:0012120) | 1.67041777 |
119 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 1.66756796 |
120 | IgG deficiency (HP:0004315) | 1.64832721 |
121 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.64730911 |
122 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.64730911 |
123 | Nasolacrimal duct obstruction (HP:0000579) | 1.64227333 |
124 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.63007893 |
125 | Poikiloderma (HP:0001029) | 1.62781405 |
126 | Onycholysis (HP:0001806) | 1.62095242 |
127 | Nephrogenic diabetes insipidus (HP:0009806) | 1.62031870 |
128 | Vaginal atresia (HP:0000148) | 1.61801264 |
129 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.60687691 |
130 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.60176302 |
131 | Agammaglobulinemia (HP:0004432) | 1.60134655 |
132 | Microretrognathia (HP:0000308) | 1.59910950 |
133 | Anencephaly (HP:0002323) | 1.59452712 |
134 | Nasal polyposis (HP:0100582) | 1.58621578 |
135 | Pancytopenia (HP:0001876) | 1.58480507 |
136 | Lactic acidosis (HP:0003128) | 1.57350287 |
137 | Ridged nail (HP:0001807) | 1.55505472 |
138 | Seborrheic dermatitis (HP:0001051) | 1.55208808 |
139 | Recurrent abscess formation (HP:0002722) | 1.54158580 |
140 | Septate vagina (HP:0001153) | 1.53918627 |
141 | Leukodystrophy (HP:0002415) | 1.53702582 |
142 | Myositis (HP:0100614) | 1.52950943 |
143 | Pustule (HP:0200039) | 1.52619773 |
144 | Cerebral edema (HP:0002181) | 1.52226686 |
145 | Breast hypoplasia (HP:0003187) | 1.51374051 |
146 | Anhidrosis (HP:0000970) | 1.50865288 |
147 | Duplication of thumb phalanx (HP:0009942) | 1.50371909 |
Rank | Gene Set | Z-score |
---|---|---|
1 | NME2 | 5.66393258 |
2 | VRK2 | 5.07914419 |
3 | STK16 | 3.18907161 |
4 | MST4 | 3.07834186 |
5 | ZAK | 2.99053522 |
6 | TLK1 | 2.67337229 |
7 | BUB1 | 2.55272882 |
8 | LRRK2 | 2.49474420 |
9 | PIM2 | 2.49163458 |
10 | RPS6KB2 | 2.34140676 |
11 | VRK1 | 2.33499874 |
12 | MAP4K1 | 2.19925826 |
13 | WEE1 | 2.19292216 |
14 | SRPK1 | 1.99200527 |
15 | NUAK1 | 1.95845480 |
16 | TGFBR1 | 1.95372523 |
17 | DYRK3 | 1.91689186 |
18 | CDK19 | 1.86582836 |
19 | TAF1 | 1.83452466 |
20 | PNCK | 1.78526774 |
21 | BLK | 1.70859265 |
22 | KDR | 1.67975697 |
23 | EEF2K | 1.59007577 |
24 | NME1 | 1.55280997 |
25 | TEC | 1.43619385 |
26 | BTK | 1.43290085 |
27 | BCKDK | 1.43201238 |
28 | WNK3 | 1.36551705 |
29 | TAOK3 | 1.34160438 |
30 | KIT | 1.32501423 |
31 | EIF2AK3 | 1.29904327 |
32 | MAP3K4 | 1.29643174 |
33 | ILK | 1.29436412 |
34 | MAP4K2 | 1.24657097 |
35 | IKBKB | 1.22273273 |
36 | IRAK4 | 1.21203035 |
37 | MUSK | 1.21099300 |
38 | PASK | 1.19818407 |
39 | TYK2 | 1.19400524 |
40 | ACVR1B | 1.16227296 |
41 | TNIK | 1.14390717 |
42 | MAPKAPK3 | 1.14070554 |
43 | GRK7 | 1.13342739 |
44 | MAPKAPK5 | 1.12983300 |
45 | MKNK1 | 1.12632765 |
46 | INSRR | 1.10609041 |
47 | SYK | 1.09476965 |
48 | GRK6 | 1.08331620 |
49 | RPS6KA4 | 1.07098153 |
50 | NLK | 1.05094079 |
51 | MAP3K3 | 1.04044063 |
52 | EIF2AK1 | 1.03648374 |
53 | PBK | 1.00437020 |
54 | MAP2K7 | 0.96321506 |
55 | AURKB | 0.96176345 |
56 | RPS6KA5 | 0.95771381 |
57 | TESK2 | 0.95634531 |
58 | FGFR2 | 0.94995734 |
59 | WNK4 | 0.93687867 |
60 | PLK4 | 0.92483838 |
61 | MAP2K2 | 0.91972525 |
62 | PINK1 | 0.91073684 |
63 | BMPR1B | 0.90243289 |
64 | PLK3 | 0.87825019 |
65 | OXSR1 | 0.87166021 |
66 | CDK7 | 0.86708526 |
67 | TXK | 0.85744470 |
68 | MAP3K12 | 0.85459162 |
69 | ADRBK2 | 0.84969938 |
70 | IKBKE | 0.84683010 |
71 | ZAP70 | 0.81590478 |
72 | CDK3 | 0.81442301 |
73 | PIM1 | 0.79812315 |
74 | IRAK3 | 0.79340322 |
75 | TBK1 | 0.79281236 |
76 | LYN | 0.79091279 |
77 | CSNK2A2 | 0.76918362 |
78 | TGFBR2 | 0.76040340 |
79 | LCK | 0.75702678 |
80 | STK10 | 0.74685999 |
81 | DYRK2 | 0.73609108 |
82 | ITK | 0.73588964 |
83 | EIF2AK2 | 0.71898778 |
84 | CSF1R | 0.69742250 |
85 | FLT3 | 0.69702164 |
86 | CHEK2 | 0.69574594 |
87 | PRKCG | 0.68843955 |
88 | GRK1 | 0.67726997 |
89 | AURKA | 0.65364054 |
90 | CDC7 | 0.64175456 |
91 | CSNK2A1 | 0.64103865 |
92 | FES | 0.63643014 |
93 | MYLK | 0.63592180 |
94 | MST1R | 0.63011547 |
95 | MAP3K11 | 0.62692384 |
96 | MAPK4 | 0.62550302 |
97 | NEK2 | 0.61918872 |
98 | MAPK15 | 0.60969569 |
99 | CDK8 | 0.59391584 |
100 | JAK3 | 0.58539811 |
101 | TSSK6 | 0.54442361 |
102 | YES1 | 0.52970795 |
103 | MAP2K3 | 0.52545764 |
104 | NTRK2 | 0.52491352 |
105 | CLK1 | 0.50959875 |
106 | ADRBK1 | 0.50959118 |
107 | MKNK2 | 0.50537054 |
108 | ATR | 0.48832133 |
109 | DAPK3 | 0.48761756 |
110 | MAPK13 | 0.48239317 |
111 | BRSK2 | 0.47879537 |
112 | CSNK1G3 | 0.45566368 |
113 | MATK | 0.45536499 |
114 | ABL2 | 0.44855735 |
115 | CAMKK2 | 0.44360761 |
116 | PRKCQ | 0.44211191 |
117 | PAK1 | 0.44189482 |
118 | MAP2K4 | 0.44033493 |
119 | PIK3CG | 0.42938111 |
120 | CCNB1 | 0.41794238 |
121 | MAPKAPK2 | 0.41255534 |
122 | DYRK1B | 0.40900560 |
123 | PAK2 | 0.40887906 |
124 | PRKACA | 0.40669599 |
125 | EPHA4 | 0.39634224 |
126 | PRKCD | 0.38043577 |
127 | FGR | 0.38041756 |
128 | TIE1 | 0.37816264 |
129 | PIK3CA | 0.37704668 |
130 | CASK | 0.37428540 |
131 | TTK | 0.36785078 |
132 | MAP3K10 | 0.36287600 |
133 | MAPK7 | 0.35625283 |
134 | MOS | 0.35523463 |
135 | CSNK1E | 0.35267521 |
136 | EPHB2 | 0.35010238 |
137 | PLK1 | 0.34889132 |
138 | PRKG1 | 0.33648781 |
139 | STK24 | 0.33586867 |
140 | CAMK1 | 0.32477955 |
141 | UHMK1 | 0.32290991 |
142 | PHKG2 | 0.31176495 |
143 | PHKG1 | 0.31176495 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Ribosome_Homo sapiens_hsa03010 | 9.04602328 |
2 | Proteasome_Homo sapiens_hsa03050 | 3.40473219 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 3.15618639 |
4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.08157647 |
5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.72320215 |
6 | DNA replication_Homo sapiens_hsa03030 | 2.71444296 |
7 | Spliceosome_Homo sapiens_hsa03040 | 2.57577151 |
8 | Protein export_Homo sapiens_hsa03060 | 2.37819209 |
9 | Mismatch repair_Homo sapiens_hsa03430 | 2.21403145 |
10 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.02251359 |
11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.01437523 |
12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.95836347 |
13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.86126493 |
14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.84686013 |
15 | Homologous recombination_Homo sapiens_hsa03440 | 1.80704964 |
16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.80477412 |
17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.75213068 |
18 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.67743402 |
19 | Base excision repair_Homo sapiens_hsa03410 | 1.57644616 |
20 | RNA transport_Homo sapiens_hsa03013 | 1.34534987 |
21 | RNA degradation_Homo sapiens_hsa03018 | 1.19316320 |
22 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.18933983 |
23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.14687935 |
24 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.14286462 |
25 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.09405832 |
26 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.00159397 |
27 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.98429717 |
28 | Purine metabolism_Homo sapiens_hsa00230 | 0.96093351 |
29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.93213425 |
30 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.91172997 |
31 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.89450597 |
32 | Sulfur relay system_Homo sapiens_hsa04122 | 0.88421850 |
33 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.87190013 |
34 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.85678963 |
35 | Allograft rejection_Homo sapiens_hsa05330 | 0.83605090 |
36 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.83507354 |
37 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.81073820 |
38 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.79939251 |
39 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.79787552 |
40 | Phototransduction_Homo sapiens_hsa04744 | 0.79429699 |
41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.78390966 |
42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.77884846 |
43 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.77794189 |
44 | Asthma_Homo sapiens_hsa05310 | 0.74444219 |
45 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72772186 |
46 | Cell cycle_Homo sapiens_hsa04110 | 0.72764642 |
47 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.72128747 |
48 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70217961 |
49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.69794485 |
50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.69631673 |
51 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.68913844 |
52 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.65945840 |
53 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.65807502 |
54 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.64979763 |
55 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.64015496 |
56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.63285667 |
57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.62671183 |
58 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.62409606 |
59 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.60848665 |
60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.60109487 |
61 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.58354902 |
62 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.57747723 |
63 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.57388749 |
64 | Peroxisome_Homo sapiens_hsa04146 | 0.56338554 |
65 | Measles_Homo sapiens_hsa05162 | 0.55689066 |
66 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.54741997 |
67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.54630374 |
68 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.52385783 |
69 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.50939226 |
70 | Nicotine addiction_Homo sapiens_hsa05033 | 0.50689494 |
71 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.50148639 |
72 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.48928882 |
73 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.48812181 |
74 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.48802753 |
75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48682747 |
76 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.48106459 |
77 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.47752501 |
78 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.46853471 |
79 | Retinol metabolism_Homo sapiens_hsa00830 | 0.46097575 |
80 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.45979569 |
81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.45288362 |
82 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.44853112 |
83 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.44827452 |
84 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.44708606 |
85 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.44552840 |
86 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44497857 |
87 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.44124869 |
88 | Leishmaniasis_Homo sapiens_hsa05140 | 0.44023812 |
89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.43484944 |
90 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.43050783 |
91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42757750 |
92 | Alcoholism_Homo sapiens_hsa05034 | 0.42728954 |
93 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.40331956 |
94 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.40010404 |
95 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.39060910 |
96 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.38271595 |
97 | HTLV-I infection_Homo sapiens_hsa05166 | 0.38226053 |
98 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.37035418 |
99 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.36441187 |
100 | Apoptosis_Homo sapiens_hsa04210 | 0.36033208 |
101 | Malaria_Homo sapiens_hsa05144 | 0.35913566 |
102 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.35213809 |
103 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34812752 |
104 | Pertussis_Homo sapiens_hsa05133 | 0.34348234 |
105 | Legionellosis_Homo sapiens_hsa05134 | 0.33330983 |
106 | Metabolic pathways_Homo sapiens_hsa01100 | 0.32493985 |
107 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.32357082 |
108 | Taste transduction_Homo sapiens_hsa04742 | 0.31808607 |
109 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.29816854 |
110 | Olfactory transduction_Homo sapiens_hsa04740 | 0.28279584 |
111 | Shigellosis_Homo sapiens_hsa05131 | 0.28097008 |
112 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.28037926 |
113 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.27909580 |
114 | Mineral absorption_Homo sapiens_hsa04978 | 0.27792733 |
115 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.27653968 |
116 | Other glycan degradation_Homo sapiens_hsa00511 | 0.26562748 |
117 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.26176264 |
118 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.25474758 |
119 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.23779034 |
120 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.23270657 |
121 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.22823252 |
122 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.21980507 |
123 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.20916041 |
124 | Hepatitis B_Homo sapiens_hsa05161 | 0.20903364 |
125 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.20194225 |
126 | Platelet activation_Homo sapiens_hsa04611 | 0.19964877 |
127 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.19346791 |
128 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.19126905 |
129 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.18832726 |
130 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.18352390 |
131 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.17488386 |
132 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.17151615 |
133 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.17042041 |
134 | Pathways in cancer_Homo sapiens_hsa05200 | 0.16592489 |
135 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.15529306 |
136 | Thyroid cancer_Homo sapiens_hsa05216 | 0.14945133 |
137 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.13942745 |
138 | Influenza A_Homo sapiens_hsa05164 | 0.13914691 |
139 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.12044448 |
140 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.11169727 |
141 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.10708806 |
142 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.10471960 |