

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 6.61016927 |
| 2 | translational termination (GO:0006415) | 6.35190732 |
| 3 | maturation of SSU-rRNA (GO:0030490) | 6.26261613 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 5.41524898 |
| 5 | cotranslational protein targeting to membrane (GO:0006613) | 5.25055582 |
| 6 | behavioral response to nicotine (GO:0035095) | 5.24462169 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.23122775 |
| 8 | translational elongation (GO:0006414) | 5.17359619 |
| 9 | protein targeting to ER (GO:0045047) | 5.17109724 |
| 10 | chaperone-mediated protein transport (GO:0072321) | 5.11526834 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 4.96347883 |
| 12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.94253041 |
| 13 | viral life cycle (GO:0019058) | 4.83128730 |
| 14 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.79817414 |
| 15 | protein localization to endoplasmic reticulum (GO:0070972) | 4.79541621 |
| 16 | cellular protein complex disassembly (GO:0043624) | 4.76092673 |
| 17 | protein neddylation (GO:0045116) | 4.69564414 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 4.39885099 |
| 19 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.39885099 |
| 20 | translational initiation (GO:0006413) | 4.20075482 |
| 21 | cell proliferation in forebrain (GO:0021846) | 4.02575050 |
| 22 | protein complex disassembly (GO:0043241) | 4.01648664 |
| 23 | positive regulation of amino acid transport (GO:0051957) | 4.00572902 |
| 24 | macromolecular complex disassembly (GO:0032984) | 3.89653852 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.84730986 |
| 26 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.67758931 |
| 27 | protein complex biogenesis (GO:0070271) | 3.62642771 |
| 28 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.61641183 |
| 29 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.60078872 |
| 30 | neuron fate determination (GO:0048664) | 3.58745571 |
| 31 | protein targeting to membrane (GO:0006612) | 3.52051336 |
| 32 | positive regulation of catecholamine secretion (GO:0033605) | 3.51239341 |
| 33 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.49576421 |
| 34 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.47365465 |
| 35 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.47365465 |
| 36 | NADH dehydrogenase complex assembly (GO:0010257) | 3.47365465 |
| 37 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.45211919 |
| 38 | piRNA metabolic process (GO:0034587) | 3.44309948 |
| 39 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.41987788 |
| 40 | negative regulation of neurotransmitter secretion (GO:0046929) | 3.36271660 |
| 41 | synaptic transmission, cholinergic (GO:0007271) | 3.32023124 |
| 42 | somite development (GO:0061053) | 3.31270653 |
| 43 | ribosomal large subunit biogenesis (GO:0042273) | 3.27775326 |
| 44 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.26704164 |
| 45 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.26704164 |
| 46 | translation (GO:0006412) | 3.26230907 |
| 47 | negative regulation of amino acid transport (GO:0051956) | 3.18336926 |
| 48 | mRNA catabolic process (GO:0006402) | 3.17077477 |
| 49 | protein-cofactor linkage (GO:0018065) | 3.15540536 |
| 50 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.14999503 |
| 51 | resolution of meiotic recombination intermediates (GO:0000712) | 3.11593904 |
| 52 | transmission of nerve impulse (GO:0019226) | 3.01951944 |
| 53 | pattern specification involved in kidney development (GO:0061004) | 2.99237650 |
| 54 | DNA methylation involved in gamete generation (GO:0043046) | 2.96623630 |
| 55 | respiratory electron transport chain (GO:0022904) | 2.96365564 |
| 56 | electron transport chain (GO:0022900) | 2.95665669 |
| 57 | spinal cord association neuron differentiation (GO:0021527) | 2.91621608 |
| 58 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.87269843 |
| 59 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.86086216 |
| 60 | nucleobase catabolic process (GO:0046113) | 2.85705548 |
| 61 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.85482077 |
| 62 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.80656941 |
| 63 | kynurenine metabolic process (GO:0070189) | 2.75876669 |
| 64 | RNA catabolic process (GO:0006401) | 2.74316391 |
| 65 | DNA deamination (GO:0045006) | 2.73670717 |
| 66 | central nervous system myelination (GO:0022010) | 2.72800477 |
| 67 | axon ensheathment in central nervous system (GO:0032291) | 2.72800477 |
| 68 | cellular component biogenesis (GO:0044085) | 2.72365532 |
| 69 | negative regulation of neurotransmitter transport (GO:0051589) | 2.71897254 |
| 70 | protein localization to cilium (GO:0061512) | 2.71541574 |
| 71 | serotonin receptor signaling pathway (GO:0007210) | 2.69365234 |
| 72 | positive regulation of organic acid transport (GO:0032892) | 2.68373829 |
| 73 | nonmotile primary cilium assembly (GO:0035058) | 2.67979958 |
| 74 | regulation of cilium movement (GO:0003352) | 2.66374053 |
| 75 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.65882161 |
| 76 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.64719202 |
| 77 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.64541589 |
| 78 | epithelial cilium movement (GO:0003351) | 2.64370420 |
| 79 | retinal ganglion cell axon guidance (GO:0031290) | 2.64082821 |
| 80 | negative regulation of transcription regulatory region DNA binding (GO:2000678) | 2.63063697 |
| 81 | rRNA catabolic process (GO:0016075) | 2.62227577 |
| 82 | negative regulation of DNA-templated transcription, elongation (GO:0032785) | 2.61322121 |
| 83 | hydrogen ion transmembrane transport (GO:1902600) | 2.60667996 |
| 84 | positive regulation of respiratory burst (GO:0060267) | 2.60608996 |
| 85 | regulation of dopamine secretion (GO:0014059) | 2.59417150 |
| 86 | termination of RNA polymerase III transcription (GO:0006386) | 2.59178780 |
| 87 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.59178780 |
| 88 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.58321285 |
| 89 | regulation of microtubule-based movement (GO:0060632) | 2.58183127 |
| 90 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.57542947 |
| 91 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.57542947 |
| 92 | intracellular protein transmembrane import (GO:0044743) | 2.56724189 |
| 93 | interferon-gamma production (GO:0032609) | 2.56007845 |
| 94 | indolalkylamine metabolic process (GO:0006586) | 2.55919852 |
| 95 | tongue development (GO:0043586) | 2.55397044 |
| 96 | dendritic spine morphogenesis (GO:0060997) | 2.54844218 |
| 97 | regulation of glycogen (starch) synthase activity (GO:2000465) | 2.54363533 |
| 98 | axonal fasciculation (GO:0007413) | 2.53585026 |
| 99 | GTP biosynthetic process (GO:0006183) | 2.53412580 |
| 100 | proton transport (GO:0015992) | 2.51360484 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.51256835 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.27087892 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.26456389 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79643085 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 2.60899552 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.45975373 |
| 7 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.31745811 |
| 8 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.26053252 |
| 9 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.21686336 |
| 10 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.18838731 |
| 11 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.18437298 |
| 12 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.15432178 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.14058099 |
| 14 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.10991582 |
| 15 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.10286972 |
| 16 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.07561103 |
| 17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.02093033 |
| 18 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.94968814 |
| 19 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.93800398 |
| 20 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.92149158 |
| 21 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.92004234 |
| 22 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.90289388 |
| 23 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.90069528 |
| 24 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.89680497 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80055230 |
| 26 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.72966315 |
| 27 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.72661774 |
| 28 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.67880118 |
| 29 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.58990180 |
| 30 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.58215025 |
| 31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.57665978 |
| 32 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.55411731 |
| 33 | EWS_26573619_Chip-Seq_HEK293_Human | 1.54262909 |
| 34 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.52133627 |
| 35 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.48450031 |
| 36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.48040261 |
| 37 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.46842673 |
| 38 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.45346535 |
| 39 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.45048948 |
| 40 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.44413481 |
| 41 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.33867283 |
| 42 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.32423700 |
| 43 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.30784517 |
| 44 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.29780639 |
| 45 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.29688965 |
| 46 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.29450102 |
| 47 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.29450102 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25625509 |
| 49 | P300_19829295_ChIP-Seq_ESCs_Human | 1.22553869 |
| 50 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.22159647 |
| 51 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.21803996 |
| 52 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.20347110 |
| 53 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.19181815 |
| 54 | NCOR_22424771_ChIP-Seq_293T_Human | 1.19065672 |
| 55 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.18782823 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.18502303 |
| 57 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.18296108 |
| 58 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15194184 |
| 59 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15161306 |
| 60 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.14681358 |
| 61 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.12923015 |
| 62 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.12334870 |
| 63 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.12238462 |
| 64 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.11882973 |
| 65 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.11865138 |
| 66 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.09709271 |
| 67 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.08026030 |
| 68 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.07789880 |
| 69 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.07740791 |
| 70 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.07229007 |
| 71 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07229007 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.06642887 |
| 73 | ERA_21632823_ChIP-Seq_H3396_Human | 1.06145182 |
| 74 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.04721009 |
| 75 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.04229109 |
| 76 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.03348531 |
| 77 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.02570132 |
| 78 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.01637430 |
| 79 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.01567178 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00329331 |
| 81 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.99593983 |
| 82 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.98723739 |
| 83 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.98539159 |
| 84 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.98523344 |
| 85 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.98480122 |
| 86 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.97872314 |
| 87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96391314 |
| 88 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.95444024 |
| 89 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.94798504 |
| 90 | AR_20517297_ChIP-Seq_VCAP_Human | 0.94591746 |
| 91 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.94066692 |
| 92 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.94064469 |
| 93 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.93311445 |
| 94 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93231113 |
| 95 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.92113163 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.91743313 |
| 97 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91040192 |
| 98 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.90973060 |
| 99 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90933703 |
| 100 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.90833744 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 4.57551564 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.43512548 |
| 3 | MP0003787_abnormal_imprinting | 3.99906238 |
| 4 | MP0008877_abnormal_DNA_methylation | 3.80005532 |
| 5 | MP0003122_maternal_imprinting | 2.61790078 |
| 6 | MP0004142_abnormal_muscle_tone | 2.55639485 |
| 7 | MP0003121_genomic_imprinting | 2.28637702 |
| 8 | MP0002653_abnormal_ependyma_morphology | 2.24831773 |
| 9 | MP0002234_abnormal_pharynx_morphology | 2.16972786 |
| 10 | MP0008789_abnormal_olfactory_epithelium | 2.09926867 |
| 11 | MP0000778_abnormal_nervous_system | 2.06918710 |
| 12 | MP0003646_muscle_fatigue | 2.03537384 |
| 13 | MP0006276_abnormal_autonomic_nervous | 2.03399862 |
| 14 | MP0003123_paternal_imprinting | 1.89571665 |
| 15 | MP0002163_abnormal_gland_morphology | 1.88422438 |
| 16 | MP0001293_anophthalmia | 1.77860620 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 1.75702571 |
| 18 | MP0005499_abnormal_olfactory_system | 1.74212600 |
| 19 | MP0005394_taste/olfaction_phenotype | 1.74212600 |
| 20 | MP0002272_abnormal_nervous_system | 1.73037136 |
| 21 | MP0004885_abnormal_endolymph | 1.71701639 |
| 22 | MP0002735_abnormal_chemical_nociception | 1.69768060 |
| 23 | MP0009745_abnormal_behavioral_response | 1.68613999 |
| 24 | MP0004147_increased_porphyrin_level | 1.66083467 |
| 25 | MP0000049_abnormal_middle_ear | 1.64862708 |
| 26 | MP0002638_abnormal_pupillary_reflex | 1.61850210 |
| 27 | MP0001529_abnormal_vocalization | 1.54338524 |
| 28 | MP0002938_white_spotting | 1.52035112 |
| 29 | MP0005551_abnormal_eye_electrophysiolog | 1.51220485 |
| 30 | MP0008875_abnormal_xenobiotic_pharmacok | 1.51107556 |
| 31 | MP0000631_abnormal_neuroendocrine_gland | 1.50790360 |
| 32 | MP0005423_abnormal_somatic_nervous | 1.49885394 |
| 33 | MP0003011_delayed_dark_adaptation | 1.39695916 |
| 34 | MP0004859_abnormal_synaptic_plasticity | 1.36911540 |
| 35 | MP0001970_abnormal_pain_threshold | 1.36553877 |
| 36 | MP0002184_abnormal_innervation | 1.34299212 |
| 37 | MP0001984_abnormal_olfaction | 1.33788882 |
| 38 | MP0002557_abnormal_social/conspecific_i | 1.32412754 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.32035157 |
| 40 | MP0002572_abnormal_emotion/affect_behav | 1.31545104 |
| 41 | MP0002733_abnormal_thermal_nociception | 1.31176798 |
| 42 | MP0001485_abnormal_pinna_reflex | 1.29839190 |
| 43 | MP0001188_hyperpigmentation | 1.26852732 |
| 44 | MP0003635_abnormal_synaptic_transmissio | 1.25063437 |
| 45 | MP0003136_yellow_coat_color | 1.24255823 |
| 46 | MP0001905_abnormal_dopamine_level | 1.23092205 |
| 47 | MP0005195_abnormal_posterior_eye | 1.22457092 |
| 48 | MP0001986_abnormal_taste_sensitivity | 1.21705095 |
| 49 | MP0009046_muscle_twitch | 1.20013745 |
| 50 | MP0002736_abnormal_nociception_after | 1.19723417 |
| 51 | MP0004133_heterotaxia | 1.19155286 |
| 52 | MP0003938_abnormal_ear_development | 1.18494336 |
| 53 | MP0008872_abnormal_physiological_respon | 1.18485714 |
| 54 | MP0000955_abnormal_spinal_cord | 1.18322739 |
| 55 | MP0002063_abnormal_learning/memory/cond | 1.18206437 |
| 56 | MP0008775_abnormal_heart_ventricle | 1.16859619 |
| 57 | MP0005379_endocrine/exocrine_gland_phen | 1.14683418 |
| 58 | MP0004742_abnormal_vestibular_system | 1.11964840 |
| 59 | MP0002752_abnormal_somatic_nervous | 1.11240440 |
| 60 | MP0001919_abnormal_reproductive_system | 1.11195421 |
| 61 | MP0005386_behavior/neurological_phenoty | 1.10938883 |
| 62 | MP0004924_abnormal_behavior | 1.10938883 |
| 63 | MP0003879_abnormal_hair_cell | 1.10916819 |
| 64 | MP0002822_catalepsy | 1.08083014 |
| 65 | MP0003942_abnormal_urinary_system | 1.08021780 |
| 66 | MP0005253_abnormal_eye_physiology | 1.07333715 |
| 67 | MP0002138_abnormal_hepatobiliary_system | 1.07105908 |
| 68 | MP0002064_seizures | 1.04287148 |
| 69 | MP0005377_hearing/vestibular/ear_phenot | 1.03370491 |
| 70 | MP0003878_abnormal_ear_physiology | 1.03370491 |
| 71 | MP0005389_reproductive_system_phenotype | 1.02864856 |
| 72 | MP0001486_abnormal_startle_reflex | 1.02071576 |
| 73 | MP0000026_abnormal_inner_ear | 1.01884190 |
| 74 | MP0002734_abnormal_mechanical_nocicepti | 1.00719918 |
| 75 | MP0003195_calcinosis | 1.00045124 |
| 76 | MP0001963_abnormal_hearing_physiology | 0.98551321 |
| 77 | MP0000427_abnormal_hair_cycle | 0.98165467 |
| 78 | MP0002876_abnormal_thyroid_physiology | 0.97507115 |
| 79 | MP0002102_abnormal_ear_morphology | 0.96949254 |
| 80 | MP0005646_abnormal_pituitary_gland | 0.95727642 |
| 81 | MP0005645_abnormal_hypothalamus_physiol | 0.94565325 |
| 82 | MP0000372_irregular_coat_pigmentation | 0.94310515 |
| 83 | MP0005167_abnormal_blood-brain_barrier | 0.94242349 |
| 84 | MP0002882_abnormal_neuron_morphology | 0.91908967 |
| 85 | MP0010030_abnormal_orbit_morphology | 0.89998537 |
| 86 | MP0004043_abnormal_pH_regulation | 0.89524050 |
| 87 | MP0001440_abnormal_grooming_behavior | 0.88864799 |
| 88 | MP0005084_abnormal_gallbladder_morpholo | 0.88818306 |
| 89 | MP0002837_dystrophic_cardiac_calcinosis | 0.88521211 |
| 90 | MP0008995_early_reproductive_senescence | 0.85254649 |
| 91 | MP0001286_abnormal_eye_development | 0.84741421 |
| 92 | MP0002095_abnormal_skin_pigmentation | 0.82436441 |
| 93 | MP0001501_abnormal_sleep_pattern | 0.82145141 |
| 94 | MP0002277_abnormal_respiratory_mucosa | 0.81926449 |
| 95 | MP0002067_abnormal_sensory_capabilities | 0.80499450 |
| 96 | MP0003880_abnormal_central_pattern | 0.80261501 |
| 97 | MP0002160_abnormal_reproductive_system | 0.78743260 |
| 98 | MP0003937_abnormal_limbs/digits/tail_de | 0.77739101 |
| 99 | MP0008961_abnormal_basal_metabolism | 0.76600528 |
| 100 | MP0002152_abnormal_brain_morphology | 0.76435692 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.96440745 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.22776282 |
| 3 | Septo-optic dysplasia (HP:0100842) | 3.84819255 |
| 4 | Type II lissencephaly (HP:0007260) | 3.71385568 |
| 5 | Pancreatic fibrosis (HP:0100732) | 3.60094914 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 3.57759879 |
| 7 | Molar tooth sign on MRI (HP:0002419) | 3.57759879 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.52098552 |
| 9 | Medial flaring of the eyebrow (HP:0010747) | 3.34366731 |
| 10 | Stenosis of the external auditory canal (HP:0000402) | 3.34212301 |
| 11 | Macrocytic anemia (HP:0001972) | 3.23284069 |
| 12 | Nephronophthisis (HP:0000090) | 3.19627564 |
| 13 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.19137941 |
| 14 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.12862875 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.08490484 |
| 16 | Acute encephalopathy (HP:0006846) | 3.06613843 |
| 17 | Pancreatic cysts (HP:0001737) | 3.05896321 |
| 18 | Pendular nystagmus (HP:0012043) | 3.01925719 |
| 19 | Mitochondrial inheritance (HP:0001427) | 3.01485441 |
| 20 | Progressive macrocephaly (HP:0004481) | 2.94024564 |
| 21 | Increased hepatocellular lipid droplets (HP:0006565) | 2.86150323 |
| 22 | True hermaphroditism (HP:0010459) | 2.77399699 |
| 23 | Myokymia (HP:0002411) | 2.77384342 |
| 24 | Agitation (HP:0000713) | 2.75101143 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 2.74363572 |
| 26 | Cerebral edema (HP:0002181) | 2.72868969 |
| 27 | Pallor (HP:0000980) | 2.69200659 |
| 28 | Absent thumb (HP:0009777) | 2.68904227 |
| 29 | Gait imbalance (HP:0002141) | 2.66251669 |
| 30 | Congenital stationary night blindness (HP:0007642) | 2.65098580 |
| 31 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.65090675 |
| 32 | Chronic hepatic failure (HP:0100626) | 2.61663492 |
| 33 | Increased CSF lactate (HP:0002490) | 2.59604310 |
| 34 | Adrenal hypoplasia (HP:0000835) | 2.57080900 |
| 35 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.54779618 |
| 36 | Absent/shortened dynein arms (HP:0200106) | 2.54779618 |
| 37 | Abnormality of the renal medulla (HP:0100957) | 2.52007173 |
| 38 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.48756939 |
| 39 | Asplenia (HP:0001746) | 2.48197119 |
| 40 | Optic disc pallor (HP:0000543) | 2.47557466 |
| 41 | Optic nerve hypoplasia (HP:0000609) | 2.42303080 |
| 42 | Congenital primary aphakia (HP:0007707) | 2.40417344 |
| 43 | Absent septum pellucidum (HP:0001331) | 2.39141379 |
| 44 | Sclerocornea (HP:0000647) | 2.38321624 |
| 45 | Abnormality of DNA repair (HP:0003254) | 2.34291435 |
| 46 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.32672527 |
| 47 | Hyperthyroidism (HP:0000836) | 2.30060844 |
| 48 | Nephrogenic diabetes insipidus (HP:0009806) | 2.28182212 |
| 49 | Growth hormone deficiency (HP:0000824) | 2.26480588 |
| 50 | Abnormal hemoglobin (HP:0011902) | 2.25095519 |
| 51 | Renal Fanconi syndrome (HP:0001994) | 2.24903551 |
| 52 | Lissencephaly (HP:0001339) | 2.22664287 |
| 53 | Retinal dysplasia (HP:0007973) | 2.22093659 |
| 54 | Pachygyria (HP:0001302) | 2.20442390 |
| 55 | Abnormality of the renal collecting system (HP:0004742) | 2.20081172 |
| 56 | Short 1st metacarpal (HP:0010034) | 2.15030030 |
| 57 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 2.15030030 |
| 58 | Cystic liver disease (HP:0006706) | 2.14746681 |
| 59 | 3-Methylglutaconic aciduria (HP:0003535) | 2.14106485 |
| 60 | Rib fusion (HP:0000902) | 2.10782327 |
| 61 | Colon cancer (HP:0003003) | 2.09024302 |
| 62 | Abnormality of the labia minora (HP:0012880) | 2.06708730 |
| 63 | Abolished electroretinogram (ERG) (HP:0000550) | 2.04177816 |
| 64 | Maternal diabetes (HP:0009800) | 2.00251461 |
| 65 | Cerebellar dysplasia (HP:0007033) | 2.00142542 |
| 66 | Depressed nasal ridge (HP:0000457) | 1.95836267 |
| 67 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.95532824 |
| 68 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.95532824 |
| 69 | Increased intramyocellular lipid droplets (HP:0012240) | 1.95230169 |
| 70 | Increased corneal curvature (HP:0100692) | 1.93696530 |
| 71 | Keratoconus (HP:0000563) | 1.93696530 |
| 72 | Vaginal atresia (HP:0000148) | 1.93316725 |
| 73 | Anencephaly (HP:0002323) | 1.91042005 |
| 74 | Abnormal ciliary motility (HP:0012262) | 1.90848427 |
| 75 | Abnormality of the 1st metacarpal (HP:0010009) | 1.90286088 |
| 76 | Tubular atrophy (HP:0000092) | 1.89646542 |
| 77 | Hepatocellular necrosis (HP:0001404) | 1.89526756 |
| 78 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.89293072 |
| 79 | Abnormal number of incisors (HP:0011064) | 1.87885769 |
| 80 | Increased serum lactate (HP:0002151) | 1.87503812 |
| 81 | Hypoplasia of the radius (HP:0002984) | 1.86205578 |
| 82 | Genital tract atresia (HP:0001827) | 1.84582480 |
| 83 | Ectopic kidney (HP:0000086) | 1.83819279 |
| 84 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.82813485 |
| 85 | Abnormality of the pons (HP:0007361) | 1.82601726 |
| 86 | Poor coordination (HP:0002370) | 1.82491418 |
| 87 | Neoplasm of the adrenal cortex (HP:0100641) | 1.82470289 |
| 88 | Polyphagia (HP:0002591) | 1.81575889 |
| 89 | Hypoplasia of the pons (HP:0012110) | 1.81325110 |
| 90 | Postaxial hand polydactyly (HP:0001162) | 1.80674703 |
| 91 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 1.80336254 |
| 92 | Hypoplasia of the brainstem (HP:0002365) | 1.80336254 |
| 93 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.79898542 |
| 94 | Lactic acidosis (HP:0003128) | 1.78647133 |
| 95 | Chorioretinal atrophy (HP:0000533) | 1.76601506 |
| 96 | Lethargy (HP:0001254) | 1.75499028 |
| 97 | Hypoplasia of the ulna (HP:0003022) | 1.74948998 |
| 98 | Poor suck (HP:0002033) | 1.73659622 |
| 99 | Holoprosencephaly (HP:0001360) | 1.72594989 |
| 100 | Thyroid-stimulating hormone excess (HP:0002925) | 1.71473332 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BCKDK | 5.97101057 |
| 2 | STK16 | 4.43101966 |
| 3 | WNK4 | 2.59382727 |
| 4 | CDK19 | 2.55174568 |
| 5 | MAP4K2 | 2.51747213 |
| 6 | TIE1 | 2.43085655 |
| 7 | DYRK2 | 2.33825897 |
| 8 | NUAK1 | 2.30470569 |
| 9 | BMPR1B | 2.23371599 |
| 10 | FRK | 2.14141657 |
| 11 | EIF2AK3 | 2.09261936 |
| 12 | PINK1 | 2.01383559 |
| 13 | EPHB2 | 1.98476626 |
| 14 | ADRBK2 | 1.92212945 |
| 15 | GRK1 | 1.91840496 |
| 16 | TNIK | 1.87910783 |
| 17 | WNK3 | 1.79849390 |
| 18 | PIK3CA | 1.77927313 |
| 19 | ZAK | 1.70707857 |
| 20 | TAOK3 | 1.68218515 |
| 21 | MARK1 | 1.67756565 |
| 22 | TYRO3 | 1.48001038 |
| 23 | MAPK13 | 1.40782021 |
| 24 | NTRK2 | 1.34867592 |
| 25 | MAP2K7 | 1.24826254 |
| 26 | VRK2 | 1.14733270 |
| 27 | MAP3K9 | 1.13130610 |
| 28 | STK39 | 0.97220373 |
| 29 | MAP3K4 | 0.96423525 |
| 30 | CASK | 0.91783574 |
| 31 | TLK1 | 0.89942645 |
| 32 | PRKCG | 0.89559547 |
| 33 | TXK | 0.89318642 |
| 34 | STK11 | 0.89316208 |
| 35 | PHKG2 | 0.85450679 |
| 36 | PHKG1 | 0.85450679 |
| 37 | CAMKK2 | 0.84439962 |
| 38 | CAMK1 | 0.83581482 |
| 39 | VRK1 | 0.82834107 |
| 40 | MUSK | 0.82806619 |
| 41 | OXSR1 | 0.81291997 |
| 42 | CDK8 | 0.80121215 |
| 43 | TGFBR1 | 0.78343294 |
| 44 | INSRR | 0.78176923 |
| 45 | PRKCH | 0.75455731 |
| 46 | MINK1 | 0.75130373 |
| 47 | TEC | 0.70919637 |
| 48 | DYRK1B | 0.69131150 |
| 49 | PAK3 | 0.67565126 |
| 50 | EIF2AK2 | 0.65904481 |
| 51 | PIM2 | 0.64707502 |
| 52 | MAP3K11 | 0.63784516 |
| 53 | NME1 | 0.62120475 |
| 54 | TAF1 | 0.61286578 |
| 55 | PRKCQ | 0.59585897 |
| 56 | ADRBK1 | 0.59473211 |
| 57 | AURKA | 0.59466711 |
| 58 | PRKACA | 0.59384791 |
| 59 | TRIM28 | 0.59301473 |
| 60 | PRKD3 | 0.59072875 |
| 61 | MAPK15 | 0.58917815 |
| 62 | ACVR1B | 0.56945757 |
| 63 | CSNK1G2 | 0.56402299 |
| 64 | NTRK3 | 0.55284604 |
| 65 | PRKCZ | 0.55032540 |
| 66 | IKBKB | 0.51598164 |
| 67 | DYRK3 | 0.50832540 |
| 68 | ATR | 0.50386544 |
| 69 | FES | 0.50349477 |
| 70 | CSNK1G3 | 0.46667018 |
| 71 | FGFR2 | 0.45600280 |
| 72 | DYRK1A | 0.44745884 |
| 73 | SGK494 | 0.44134591 |
| 74 | SGK223 | 0.44134591 |
| 75 | PLK4 | 0.43743403 |
| 76 | PLK2 | 0.43718580 |
| 77 | DAPK3 | 0.43393865 |
| 78 | CAMKK1 | 0.41779313 |
| 79 | PRKCI | 0.41729340 |
| 80 | PRKCD | 0.41550925 |
| 81 | CAMK1D | 0.41471328 |
| 82 | CSNK2A2 | 0.40526951 |
| 83 | WNK1 | 0.39581702 |
| 84 | CDK5 | 0.39368308 |
| 85 | CSNK1E | 0.39356581 |
| 86 | CAMK2A | 0.38948539 |
| 87 | ERBB2 | 0.38574644 |
| 88 | PIM1 | 0.38145154 |
| 89 | RPS6KA6 | 0.38082498 |
| 90 | PRKCA | 0.37866879 |
| 91 | PRKCE | 0.37510410 |
| 92 | ARAF | 0.37029520 |
| 93 | CSNK1A1L | 0.36416293 |
| 94 | PLK3 | 0.36272903 |
| 95 | ABL2 | 0.36220176 |
| 96 | NEK2 | 0.35264390 |
| 97 | BRAF | 0.34993271 |
| 98 | KIT | 0.33891428 |
| 99 | AURKB | 0.33353183 |
| 100 | CSNK1A1 | 0.33259109 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.76699795 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.89650912 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.13567046 |
| 4 | Sulfur relay system_Homo sapiens_hsa04122 | 3.12773825 |
| 5 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.57893381 |
| 6 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.38416168 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.36177275 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.26548889 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.19250732 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.15742938 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.11295122 |
| 12 | Nicotine addiction_Homo sapiens_hsa05033 | 2.08065675 |
| 13 | Phototransduction_Homo sapiens_hsa04744 | 2.07360189 |
| 14 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.03642032 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.98811891 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.71357179 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.70265972 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.70255151 |
| 19 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.51606048 |
| 20 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.50742446 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.47544114 |
| 22 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.45573776 |
| 23 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.41918627 |
| 24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.41861440 |
| 25 | Asthma_Homo sapiens_hsa05310 | 1.39589253 |
| 26 | Morphine addiction_Homo sapiens_hsa05032 | 1.35180750 |
| 27 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.34100062 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.33660619 |
| 29 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.20182035 |
| 30 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.14986314 |
| 31 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.13728461 |
| 32 | Proteasome_Homo sapiens_hsa03050 | 1.11995642 |
| 33 | Homologous recombination_Homo sapiens_hsa03440 | 1.06811450 |
| 34 | Olfactory transduction_Homo sapiens_hsa04740 | 1.02961348 |
| 35 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.98230839 |
| 36 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.96459251 |
| 37 | Peroxisome_Homo sapiens_hsa04146 | 0.95866633 |
| 38 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.95510525 |
| 39 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.95412078 |
| 40 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.94490395 |
| 41 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.89432981 |
| 42 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.87168909 |
| 43 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.86725367 |
| 44 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.85739347 |
| 45 | Insulin secretion_Homo sapiens_hsa04911 | 0.82582106 |
| 46 | Retinol metabolism_Homo sapiens_hsa00830 | 0.82078244 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.81015600 |
| 48 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.79681206 |
| 49 | GABAergic synapse_Homo sapiens_hsa04727 | 0.78567466 |
| 50 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.77373761 |
| 51 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74964890 |
| 52 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.73874989 |
| 53 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.72086987 |
| 54 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.71307459 |
| 55 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.70419121 |
| 56 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.70391152 |
| 57 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67379038 |
| 58 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.66474321 |
| 59 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66403481 |
| 60 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65753601 |
| 61 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.63996830 |
| 62 | Axon guidance_Homo sapiens_hsa04360 | 0.63760113 |
| 63 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.63051868 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.62613330 |
| 65 | Salivary secretion_Homo sapiens_hsa04970 | 0.62462290 |
| 66 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.62228751 |
| 67 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.61872728 |
| 68 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.60842732 |
| 69 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.59765502 |
| 70 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59153474 |
| 71 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.59104689 |
| 72 | Mineral absorption_Homo sapiens_hsa04978 | 0.58664189 |
| 73 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.58030180 |
| 74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.57617509 |
| 75 | Taste transduction_Homo sapiens_hsa04742 | 0.56401922 |
| 76 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.54528846 |
| 77 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.54095014 |
| 78 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.54069842 |
| 79 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.53692497 |
| 80 | Purine metabolism_Homo sapiens_hsa00230 | 0.52783538 |
| 81 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.52040561 |
| 82 | Allograft rejection_Homo sapiens_hsa05330 | 0.51820486 |
| 83 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.49920576 |
| 84 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.48864075 |
| 85 | Circadian entrainment_Homo sapiens_hsa04713 | 0.47203922 |
| 86 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.46024540 |
| 87 | RNA transport_Homo sapiens_hsa03013 | 0.44972304 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.44720574 |
| 89 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.42589332 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.37820951 |
| 91 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.37726029 |
| 92 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.36603103 |
| 93 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.36300181 |
| 94 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.35900490 |
| 95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.32341027 |
| 96 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.31044088 |
| 97 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.30423630 |
| 98 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.29472114 |
| 99 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.27657218 |
| 100 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.27644330 |

