RPL34P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)6.61016927
2translational termination (GO:0006415)6.35190732
3maturation of SSU-rRNA (GO:0030490)6.26261613
4ribosomal small subunit biogenesis (GO:0042274)5.41524898
5cotranslational protein targeting to membrane (GO:0006613)5.25055582
6behavioral response to nicotine (GO:0035095)5.24462169
7SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.23122775
8translational elongation (GO:0006414)5.17359619
9protein targeting to ER (GO:0045047)5.17109724
10chaperone-mediated protein transport (GO:0072321)5.11526834
11ribosomal small subunit assembly (GO:0000028)4.96347883
12establishment of protein localization to endoplasmic reticulum (GO:0072599)4.94253041
13viral life cycle (GO:0019058)4.83128730
14nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.79817414
15protein localization to endoplasmic reticulum (GO:0070972)4.79541621
16cellular protein complex disassembly (GO:0043624)4.76092673
17protein neddylation (GO:0045116)4.69564414
18ATP synthesis coupled proton transport (GO:0015986)4.39885099
19energy coupled proton transport, down electrochemical gradient (GO:0015985)4.39885099
20translational initiation (GO:0006413)4.20075482
21cell proliferation in forebrain (GO:0021846)4.02575050
22protein complex disassembly (GO:0043241)4.01648664
23positive regulation of amino acid transport (GO:0051957)4.00572902
24macromolecular complex disassembly (GO:0032984)3.89653852
25establishment of protein localization to mitochondrial membrane (GO:0090151)3.84730986
26mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.67758931
27protein complex biogenesis (GO:0070271)3.62642771
28epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.61641183
29pyrimidine nucleobase catabolic process (GO:0006208)3.60078872
30neuron fate determination (GO:0048664)3.58745571
31protein targeting to membrane (GO:0006612)3.52051336
32positive regulation of catecholamine secretion (GO:0033605)3.51239341
33negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)3.49576421
34mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.47365465
35mitochondrial respiratory chain complex I assembly (GO:0032981)3.47365465
36NADH dehydrogenase complex assembly (GO:0010257)3.47365465
37mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.45211919
38piRNA metabolic process (GO:0034587)3.44309948
39nuclear-transcribed mRNA catabolic process (GO:0000956)3.41987788
40negative regulation of neurotransmitter secretion (GO:0046929)3.36271660
41synaptic transmission, cholinergic (GO:0007271)3.32023124
42somite development (GO:0061053)3.31270653
43ribosomal large subunit biogenesis (GO:0042273)3.27775326
44substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.26704164
45substrate-independent telencephalic tangential migration (GO:0021826)3.26704164
46translation (GO:0006412)3.26230907
47negative regulation of amino acid transport (GO:0051956)3.18336926
48mRNA catabolic process (GO:0006402)3.17077477
49protein-cofactor linkage (GO:0018065)3.15540536
50mitochondrial respiratory chain complex assembly (GO:0033108)3.14999503
51resolution of meiotic recombination intermediates (GO:0000712)3.11593904
52transmission of nerve impulse (GO:0019226)3.01951944
53pattern specification involved in kidney development (GO:0061004)2.99237650
54DNA methylation involved in gamete generation (GO:0043046)2.96623630
55respiratory electron transport chain (GO:0022904)2.96365564
56electron transport chain (GO:0022900)2.95665669
57spinal cord association neuron differentiation (GO:0021527)2.91621608
58nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87269843
59water-soluble vitamin biosynthetic process (GO:0042364)2.86086216
60nucleobase catabolic process (GO:0046113)2.85705548
61exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.85482077
62cerebral cortex radially oriented cell migration (GO:0021799)2.80656941
63kynurenine metabolic process (GO:0070189)2.75876669
64RNA catabolic process (GO:0006401)2.74316391
65DNA deamination (GO:0045006)2.73670717
66central nervous system myelination (GO:0022010)2.72800477
67axon ensheathment in central nervous system (GO:0032291)2.72800477
68cellular component biogenesis (GO:0044085)2.72365532
69negative regulation of neurotransmitter transport (GO:0051589)2.71897254
70protein localization to cilium (GO:0061512)2.71541574
71serotonin receptor signaling pathway (GO:0007210)2.69365234
72positive regulation of organic acid transport (GO:0032892)2.68373829
73nonmotile primary cilium assembly (GO:0035058)2.67979958
74regulation of cilium movement (GO:0003352)2.66374053
75ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.65882161
76regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.64719202
77detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.64541589
78epithelial cilium movement (GO:0003351)2.64370420
79retinal ganglion cell axon guidance (GO:0031290)2.64082821
80negative regulation of transcription regulatory region DNA binding (GO:2000678)2.63063697
81rRNA catabolic process (GO:0016075)2.62227577
82negative regulation of DNA-templated transcription, elongation (GO:0032785)2.61322121
83hydrogen ion transmembrane transport (GO:1902600)2.60667996
84positive regulation of respiratory burst (GO:0060267)2.60608996
85regulation of dopamine secretion (GO:0014059)2.59417150
86termination of RNA polymerase III transcription (GO:0006386)2.59178780
87transcription elongation from RNA polymerase III promoter (GO:0006385)2.59178780
88ribonucleoprotein complex biogenesis (GO:0022613)2.58321285
89regulation of microtubule-based movement (GO:0060632)2.58183127
90RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.57542947
91tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.57542947
92intracellular protein transmembrane import (GO:0044743)2.56724189
93interferon-gamma production (GO:0032609)2.56007845
94indolalkylamine metabolic process (GO:0006586)2.55919852
95tongue development (GO:0043586)2.55397044
96dendritic spine morphogenesis (GO:0060997)2.54844218
97regulation of glycogen (starch) synthase activity (GO:2000465)2.54363533
98axonal fasciculation (GO:0007413)2.53585026
99GTP biosynthetic process (GO:0006183)2.53412580
100proton transport (GO:0015992)2.51360484

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.51256835
2E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.27087892
3TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat3.26456389
4GABP_17652178_ChIP-ChIP_JURKAT_Human2.79643085
5VDR_22108803_ChIP-Seq_LS180_Human2.60899552
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.45975373
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.31745811
8CBX2_27304074_Chip-Seq_ESCs_Mouse2.26053252
9RBPJ_22232070_ChIP-Seq_NCS_Mouse2.21686336
10BMI1_23680149_ChIP-Seq_NPCS_Mouse2.18838731
11EZH2_27304074_Chip-Seq_ESCs_Mouse2.18437298
12ZNF274_21170338_ChIP-Seq_K562_Hela2.15432178
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.14058099
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.10991582
15GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.10286972
16IGF1R_20145208_ChIP-Seq_DFB_Human2.07561103
17GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.02093033
18JARID2_20064375_ChIP-Seq_MESCs_Mouse1.94968814
19SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.93800398
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.92149158
21REST_21632747_ChIP-Seq_MESCs_Mouse1.92004234
22IRF1_19129219_ChIP-ChIP_H3396_Human1.90289388
23EED_16625203_ChIP-ChIP_MESCs_Mouse1.90069528
24RNF2_27304074_Chip-Seq_NSC_Mouse1.89680497
25MYC_18940864_ChIP-ChIP_HL60_Human1.80055230
26EZH2_27294783_Chip-Seq_ESCs_Mouse1.72966315
27CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.72661774
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.67880118
29MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.58990180
30MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.58215025
31EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.57665978
32ETS1_20019798_ChIP-Seq_JURKAT_Human1.55411731
33EWS_26573619_Chip-Seq_HEK293_Human1.54262909
34REST_18959480_ChIP-ChIP_MESCs_Mouse1.52133627
35ZFP57_27257070_Chip-Seq_ESCs_Mouse1.48450031
36TP53_22573176_ChIP-Seq_HFKS_Human1.48040261
37RNF2_27304074_Chip-Seq_ESCs_Mouse1.46842673
38JARID2_20075857_ChIP-Seq_MESCs_Mouse1.45346535
39SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.45048948
40CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.44413481
41FLI1_27457419_Chip-Seq_LIVER_Mouse1.33867283
42PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.32423700
43POU5F1_16153702_ChIP-ChIP_HESCs_Human1.30784517
44JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.29780639
45SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.29688965
46RNF2_18974828_ChIP-Seq_MESCs_Mouse1.29450102
47EZH2_18974828_ChIP-Seq_MESCs_Mouse1.29450102
48CTBP1_25329375_ChIP-Seq_LNCAP_Human1.25625509
49P300_19829295_ChIP-Seq_ESCs_Human1.22553869
50CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.22159647
51ELK1_19687146_ChIP-ChIP_HELA_Human1.21803996
52IKZF1_21737484_ChIP-ChIP_HCT116_Human1.20347110
53SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.19181815
54NCOR_22424771_ChIP-Seq_293T_Human1.19065672
55ETV2_25802403_ChIP-Seq_MESCs_Mouse1.18782823
56FUS_26573619_Chip-Seq_HEK293_Human1.18502303
57ELF1_17652178_ChIP-ChIP_JURKAT_Human1.18296108
58GATA3_21878914_ChIP-Seq_MCF-7_Human1.15194184
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.15161306
60CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.14681358
61SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.12923015
62RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.12334870
63SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.12238462
64CTBP2_25329375_ChIP-Seq_LNCAP_Human1.11882973
65SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.11865138
66TP53_20018659_ChIP-ChIP_R1E_Mouse1.09709271
67PRDM14_20953172_ChIP-Seq_ESCs_Human1.08026030
68VDR_23849224_ChIP-Seq_CD4+_Human1.07789880
69TTF2_22483619_ChIP-Seq_HELA_Human1.07740791
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.07229007
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07229007
72GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.06642887
73ERA_21632823_ChIP-Seq_H3396_Human1.06145182
74RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.04721009
75TP63_19390658_ChIP-ChIP_HaCaT_Human1.04229109
76RING1B_27294783_Chip-Seq_ESCs_Mouse1.03348531
77PCGF2_27294783_Chip-Seq_ESCs_Mouse1.02570132
78KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01637430
79RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.01567178
80AUTS2_25519132_ChIP-Seq_293T-REX_Human1.00329331
81PCGF2_27294783_Chip-Seq_NPCs_Mouse0.99593983
82CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.98723739
83SUZ12_18974828_ChIP-Seq_MESCs_Mouse0.98539159
84YY1_21170310_ChIP-Seq_MESCs_Mouse0.98523344
85FOXP3_21729870_ChIP-Seq_TREG_Human0.98480122
86NANOG_20526341_ChIP-Seq_ESCs_Human0.97872314
87TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.96391314
88PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.95444024
89TAF2_19829295_ChIP-Seq_ESCs_Human0.94798504
90AR_20517297_ChIP-Seq_VCAP_Human0.94591746
91P53_21459846_ChIP-Seq_SAOS-2_Human0.94066692
92MYC_19829295_ChIP-Seq_ESCs_Human0.94064469
93MTF2_20144788_ChIP-Seq_MESCs_Mouse0.93311445
94GBX2_23144817_ChIP-Seq_PC3_Human0.93231113
95RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.92113163
96TCF4_22108803_ChIP-Seq_LS180_Human0.91743313
97TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.91040192
98TDRD3_21172665_ChIP-Seq_MCF-7_Human0.90973060
99FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.90933703
100CBP_20019798_ChIP-Seq_JUKART_Human0.90833744

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode4.57551564
2MP0009379_abnormal_foot_pigmentation4.43512548
3MP0003787_abnormal_imprinting3.99906238
4MP0008877_abnormal_DNA_methylation3.80005532
5MP0003122_maternal_imprinting2.61790078
6MP0004142_abnormal_muscle_tone2.55639485
7MP0003121_genomic_imprinting2.28637702
8MP0002653_abnormal_ependyma_morphology2.24831773
9MP0002234_abnormal_pharynx_morphology2.16972786
10MP0008789_abnormal_olfactory_epithelium2.09926867
11MP0000778_abnormal_nervous_system2.06918710
12MP0003646_muscle_fatigue2.03537384
13MP0006276_abnormal_autonomic_nervous2.03399862
14MP0003123_paternal_imprinting1.89571665
15MP0002163_abnormal_gland_morphology1.88422438
16MP0001293_anophthalmia1.77860620
17MP0006072_abnormal_retinal_apoptosis1.75702571
18MP0005499_abnormal_olfactory_system1.74212600
19MP0005394_taste/olfaction_phenotype1.74212600
20MP0002272_abnormal_nervous_system1.73037136
21MP0004885_abnormal_endolymph1.71701639
22MP0002735_abnormal_chemical_nociception1.69768060
23MP0009745_abnormal_behavioral_response1.68613999
24MP0004147_increased_porphyrin_level1.66083467
25MP0000049_abnormal_middle_ear1.64862708
26MP0002638_abnormal_pupillary_reflex1.61850210
27MP0001529_abnormal_vocalization1.54338524
28MP0002938_white_spotting1.52035112
29MP0005551_abnormal_eye_electrophysiolog1.51220485
30MP0008875_abnormal_xenobiotic_pharmacok1.51107556
31MP0000631_abnormal_neuroendocrine_gland1.50790360
32MP0005423_abnormal_somatic_nervous1.49885394
33MP0003011_delayed_dark_adaptation1.39695916
34MP0004859_abnormal_synaptic_plasticity1.36911540
35MP0001970_abnormal_pain_threshold1.36553877
36MP0002184_abnormal_innervation1.34299212
37MP0001984_abnormal_olfaction1.33788882
38MP0002557_abnormal_social/conspecific_i1.32412754
39MP0001968_abnormal_touch/_nociception1.32035157
40MP0002572_abnormal_emotion/affect_behav1.31545104
41MP0002733_abnormal_thermal_nociception1.31176798
42MP0001485_abnormal_pinna_reflex1.29839190
43MP0001188_hyperpigmentation1.26852732
44MP0003635_abnormal_synaptic_transmissio1.25063437
45MP0003136_yellow_coat_color1.24255823
46MP0001905_abnormal_dopamine_level1.23092205
47MP0005195_abnormal_posterior_eye1.22457092
48MP0001986_abnormal_taste_sensitivity1.21705095
49MP0009046_muscle_twitch1.20013745
50MP0002736_abnormal_nociception_after1.19723417
51MP0004133_heterotaxia1.19155286
52MP0003938_abnormal_ear_development1.18494336
53MP0008872_abnormal_physiological_respon1.18485714
54MP0000955_abnormal_spinal_cord1.18322739
55MP0002063_abnormal_learning/memory/cond1.18206437
56MP0008775_abnormal_heart_ventricle1.16859619
57MP0005379_endocrine/exocrine_gland_phen1.14683418
58MP0004742_abnormal_vestibular_system1.11964840
59MP0002752_abnormal_somatic_nervous1.11240440
60MP0001919_abnormal_reproductive_system1.11195421
61MP0005386_behavior/neurological_phenoty1.10938883
62MP0004924_abnormal_behavior1.10938883
63MP0003879_abnormal_hair_cell1.10916819
64MP0002822_catalepsy1.08083014
65MP0003942_abnormal_urinary_system1.08021780
66MP0005253_abnormal_eye_physiology1.07333715
67MP0002138_abnormal_hepatobiliary_system1.07105908
68MP0002064_seizures1.04287148
69MP0005377_hearing/vestibular/ear_phenot1.03370491
70MP0003878_abnormal_ear_physiology1.03370491
71MP0005389_reproductive_system_phenotype1.02864856
72MP0001486_abnormal_startle_reflex1.02071576
73MP0000026_abnormal_inner_ear1.01884190
74MP0002734_abnormal_mechanical_nocicepti1.00719918
75MP0003195_calcinosis1.00045124
76MP0001963_abnormal_hearing_physiology0.98551321
77MP0000427_abnormal_hair_cycle0.98165467
78MP0002876_abnormal_thyroid_physiology0.97507115
79MP0002102_abnormal_ear_morphology0.96949254
80MP0005646_abnormal_pituitary_gland0.95727642
81MP0005645_abnormal_hypothalamus_physiol0.94565325
82MP0000372_irregular_coat_pigmentation0.94310515
83MP0005167_abnormal_blood-brain_barrier0.94242349
84MP0002882_abnormal_neuron_morphology0.91908967
85MP0010030_abnormal_orbit_morphology0.89998537
86MP0004043_abnormal_pH_regulation0.89524050
87MP0001440_abnormal_grooming_behavior0.88864799
88MP0005084_abnormal_gallbladder_morpholo0.88818306
89MP0002837_dystrophic_cardiac_calcinosis0.88521211
90MP0008995_early_reproductive_senescence0.85254649
91MP0001286_abnormal_eye_development0.84741421
92MP0002095_abnormal_skin_pigmentation0.82436441
93MP0001501_abnormal_sleep_pattern0.82145141
94MP0002277_abnormal_respiratory_mucosa0.81926449
95MP0002067_abnormal_sensory_capabilities0.80499450
96MP0003880_abnormal_central_pattern0.80261501
97MP0002160_abnormal_reproductive_system0.78743260
98MP0003937_abnormal_limbs/digits/tail_de0.77739101
99MP0008961_abnormal_basal_metabolism0.76600528
100MP0002152_abnormal_brain_morphology0.76435692

Predicted human phenotypes

RankGene SetZ-score
1Reticulocytopenia (HP:0001896)4.96440745
2Abnormality of cells of the erythroid lineage (HP:0012130)4.22776282
3Septo-optic dysplasia (HP:0100842)3.84819255
4Type II lissencephaly (HP:0007260)3.71385568
5Pancreatic fibrosis (HP:0100732)3.60094914
6Abnormality of midbrain morphology (HP:0002418)3.57759879
7Molar tooth sign on MRI (HP:0002419)3.57759879
8Acute necrotizing encephalopathy (HP:0006965)3.52098552
9Medial flaring of the eyebrow (HP:0010747)3.34366731
10Stenosis of the external auditory canal (HP:0000402)3.34212301
11Macrocytic anemia (HP:0001972)3.23284069
12Nephronophthisis (HP:0000090)3.19627564
13Absent rod-and cone-mediated responses on ERG (HP:0007688)3.19137941
14Abnormal mitochondria in muscle tissue (HP:0008316)3.12862875
15Abnormal number of erythroid precursors (HP:0012131)3.08490484
16Acute encephalopathy (HP:0006846)3.06613843
17Pancreatic cysts (HP:0001737)3.05896321
18Pendular nystagmus (HP:0012043)3.01925719
19Mitochondrial inheritance (HP:0001427)3.01485441
20Progressive macrocephaly (HP:0004481)2.94024564
21Increased hepatocellular lipid droplets (HP:0006565)2.86150323
22True hermaphroditism (HP:0010459)2.77399699
23Myokymia (HP:0002411)2.77384342
24Agitation (HP:0000713)2.75101143
25Lipid accumulation in hepatocytes (HP:0006561)2.74363572
26Cerebral edema (HP:0002181)2.72868969
27Pallor (HP:0000980)2.69200659
28Absent thumb (HP:0009777)2.68904227
29Gait imbalance (HP:0002141)2.66251669
30Congenital stationary night blindness (HP:0007642)2.65098580
31Aplasia/Hypoplasia of the spleen (HP:0010451)2.65090675
32Chronic hepatic failure (HP:0100626)2.61663492
33Increased CSF lactate (HP:0002490)2.59604310
34Adrenal hypoplasia (HP:0000835)2.57080900
35Dynein arm defect of respiratory motile cilia (HP:0012255)2.54779618
36Absent/shortened dynein arms (HP:0200106)2.54779618
37Abnormality of the renal medulla (HP:0100957)2.52007173
38Abnormal rod and cone electroretinograms (HP:0008323)2.48756939
39Asplenia (HP:0001746)2.48197119
40Optic disc pallor (HP:0000543)2.47557466
41Optic nerve hypoplasia (HP:0000609)2.42303080
42Congenital primary aphakia (HP:0007707)2.40417344
43Absent septum pellucidum (HP:0001331)2.39141379
44Sclerocornea (HP:0000647)2.38321624
45Abnormality of DNA repair (HP:0003254)2.34291435
46Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.32672527
47Hyperthyroidism (HP:0000836)2.30060844
48Nephrogenic diabetes insipidus (HP:0009806)2.28182212
49Growth hormone deficiency (HP:0000824)2.26480588
50Abnormal hemoglobin (HP:0011902)2.25095519
51Renal Fanconi syndrome (HP:0001994)2.24903551
52Lissencephaly (HP:0001339)2.22664287
53Retinal dysplasia (HP:0007973)2.22093659
54Pachygyria (HP:0001302)2.20442390
55Abnormality of the renal collecting system (HP:0004742)2.20081172
56Short 1st metacarpal (HP:0010034)2.15030030
57Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.15030030
58Cystic liver disease (HP:0006706)2.14746681
593-Methylglutaconic aciduria (HP:0003535)2.14106485
60Rib fusion (HP:0000902)2.10782327
61Colon cancer (HP:0003003)2.09024302
62Abnormality of the labia minora (HP:0012880)2.06708730
63Abolished electroretinogram (ERG) (HP:0000550)2.04177816
64Maternal diabetes (HP:0009800)2.00251461
65Cerebellar dysplasia (HP:0007033)2.00142542
66Depressed nasal ridge (HP:0000457)1.95836267
67Abnormal respiratory epithelium morphology (HP:0012253)1.95532824
68Abnormal respiratory motile cilium morphology (HP:0005938)1.95532824
69Increased intramyocellular lipid droplets (HP:0012240)1.95230169
70Increased corneal curvature (HP:0100692)1.93696530
71Keratoconus (HP:0000563)1.93696530
72Vaginal atresia (HP:0000148)1.93316725
73Anencephaly (HP:0002323)1.91042005
74Abnormal ciliary motility (HP:0012262)1.90848427
75Abnormality of the 1st metacarpal (HP:0010009)1.90286088
76Tubular atrophy (HP:0000092)1.89646542
77Hepatocellular necrosis (HP:0001404)1.89526756
78Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.89293072
79Abnormal number of incisors (HP:0011064)1.87885769
80Increased serum lactate (HP:0002151)1.87503812
81Hypoplasia of the radius (HP:0002984)1.86205578
82Genital tract atresia (HP:0001827)1.84582480
83Ectopic kidney (HP:0000086)1.83819279
84Abnormal respiratory motile cilium physiology (HP:0012261)1.82813485
85Abnormality of the pons (HP:0007361)1.82601726
86Poor coordination (HP:0002370)1.82491418
87Neoplasm of the adrenal cortex (HP:0100641)1.82470289
88Polyphagia (HP:0002591)1.81575889
89Hypoplasia of the pons (HP:0012110)1.81325110
90Postaxial hand polydactyly (HP:0001162)1.80674703
91Aplasia/Hypoplasia of the brainstem (HP:0007362)1.80336254
92Hypoplasia of the brainstem (HP:0002365)1.80336254
93Aplasia/Hypoplasia of the tongue (HP:0010295)1.79898542
94Lactic acidosis (HP:0003128)1.78647133
95Chorioretinal atrophy (HP:0000533)1.76601506
96Lethargy (HP:0001254)1.75499028
97Hypoplasia of the ulna (HP:0003022)1.74948998
98Poor suck (HP:0002033)1.73659622
99Holoprosencephaly (HP:0001360)1.72594989
100Thyroid-stimulating hormone excess (HP:0002925)1.71473332

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK5.97101057
2STK164.43101966
3WNK42.59382727
4CDK192.55174568
5MAP4K22.51747213
6TIE12.43085655
7DYRK22.33825897
8NUAK12.30470569
9BMPR1B2.23371599
10FRK2.14141657
11EIF2AK32.09261936
12PINK12.01383559
13EPHB21.98476626
14ADRBK21.92212945
15GRK11.91840496
16TNIK1.87910783
17WNK31.79849390
18PIK3CA1.77927313
19ZAK1.70707857
20TAOK31.68218515
21MARK11.67756565
22TYRO31.48001038
23MAPK131.40782021
24NTRK21.34867592
25MAP2K71.24826254
26VRK21.14733270
27MAP3K91.13130610
28STK390.97220373
29MAP3K40.96423525
30CASK0.91783574
31TLK10.89942645
32PRKCG0.89559547
33TXK0.89318642
34STK110.89316208
35PHKG20.85450679
36PHKG10.85450679
37CAMKK20.84439962
38CAMK10.83581482
39VRK10.82834107
40MUSK0.82806619
41OXSR10.81291997
42CDK80.80121215
43TGFBR10.78343294
44INSRR0.78176923
45PRKCH0.75455731
46MINK10.75130373
47TEC0.70919637
48DYRK1B0.69131150
49PAK30.67565126
50EIF2AK20.65904481
51PIM20.64707502
52MAP3K110.63784516
53NME10.62120475
54TAF10.61286578
55PRKCQ0.59585897
56ADRBK10.59473211
57AURKA0.59466711
58PRKACA0.59384791
59TRIM280.59301473
60PRKD30.59072875
61MAPK150.58917815
62ACVR1B0.56945757
63CSNK1G20.56402299
64NTRK30.55284604
65PRKCZ0.55032540
66IKBKB0.51598164
67DYRK30.50832540
68ATR0.50386544
69FES0.50349477
70CSNK1G30.46667018
71FGFR20.45600280
72DYRK1A0.44745884
73SGK4940.44134591
74SGK2230.44134591
75PLK40.43743403
76PLK20.43718580
77DAPK30.43393865
78CAMKK10.41779313
79PRKCI0.41729340
80PRKCD0.41550925
81CAMK1D0.41471328
82CSNK2A20.40526951
83WNK10.39581702
84CDK50.39368308
85CSNK1E0.39356581
86CAMK2A0.38948539
87ERBB20.38574644
88PIM10.38145154
89RPS6KA60.38082498
90PRKCA0.37866879
91PRKCE0.37510410
92ARAF0.37029520
93CSNK1A1L0.36416293
94PLK30.36272903
95ABL20.36220176
96NEK20.35264390
97BRAF0.34993271
98KIT0.33891428
99AURKB0.33353183
100CSNK1A10.33259109

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.76699795
2Oxidative phosphorylation_Homo sapiens_hsa001903.89650912
3Parkinsons disease_Homo sapiens_hsa050123.13567046
4Sulfur relay system_Homo sapiens_hsa041223.12773825
5Cardiac muscle contraction_Homo sapiens_hsa042602.57893381
6Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.38416168
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.36177275
8RNA polymerase_Homo sapiens_hsa030202.26548889
9Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.19250732
10Huntingtons disease_Homo sapiens_hsa050162.15742938
11Alzheimers disease_Homo sapiens_hsa050102.11295122
12Nicotine addiction_Homo sapiens_hsa050332.08065675
13Phototransduction_Homo sapiens_hsa047442.07360189
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03642032
15Protein export_Homo sapiens_hsa030601.98811891
16Linoleic acid metabolism_Homo sapiens_hsa005911.71357179
17RNA degradation_Homo sapiens_hsa030181.70265972
18Basal transcription factors_Homo sapiens_hsa030221.70255151
19alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.51606048
20Intestinal immune network for IgA production_Homo sapiens_hsa046721.50742446
21Fanconi anemia pathway_Homo sapiens_hsa034601.47544114
22Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.45573776
23Propanoate metabolism_Homo sapiens_hsa006401.41918627
24Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.41861440
25Asthma_Homo sapiens_hsa053101.39589253
26Morphine addiction_Homo sapiens_hsa050321.35180750
27Tryptophan metabolism_Homo sapiens_hsa003801.34100062
28Nitrogen metabolism_Homo sapiens_hsa009101.33660619
29Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.20182035
30Butanoate metabolism_Homo sapiens_hsa006501.14986314
31Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.13728461
32Proteasome_Homo sapiens_hsa030501.11995642
33Homologous recombination_Homo sapiens_hsa034401.06811450
34Olfactory transduction_Homo sapiens_hsa047401.02961348
35Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.98230839
36Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.96459251
37Peroxisome_Homo sapiens_hsa041460.95866633
38Caffeine metabolism_Homo sapiens_hsa002320.95510525
39Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.95412078
40Fat digestion and absorption_Homo sapiens_hsa049750.94490395
41Hedgehog signaling pathway_Homo sapiens_hsa043400.89432981
42Basal cell carcinoma_Homo sapiens_hsa052170.87168909
43Chemical carcinogenesis_Homo sapiens_hsa052040.86725367
44Collecting duct acid secretion_Homo sapiens_hsa049660.85739347
45Insulin secretion_Homo sapiens_hsa049110.82582106
46Retinol metabolism_Homo sapiens_hsa008300.82078244
47Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.81015600
48Pyrimidine metabolism_Homo sapiens_hsa002400.79681206
49GABAergic synapse_Homo sapiens_hsa047270.78567466
50Glutamatergic synapse_Homo sapiens_hsa047240.77373761
51Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.74964890
52Serotonergic synapse_Homo sapiens_hsa047260.73874989
53Starch and sucrose metabolism_Homo sapiens_hsa005000.72086987
54Steroid hormone biosynthesis_Homo sapiens_hsa001400.71307459
55Nucleotide excision repair_Homo sapiens_hsa034200.70419121
56Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70391152
57Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.67379038
58Autoimmune thyroid disease_Homo sapiens_hsa053200.66474321
59Metabolic pathways_Homo sapiens_hsa011000.66403481
60Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.65753601
61Arachidonic acid metabolism_Homo sapiens_hsa005900.63996830
62Axon guidance_Homo sapiens_hsa043600.63760113
63beta-Alanine metabolism_Homo sapiens_hsa004100.63051868
64Pentose and glucuronate interconversions_Homo sapiens_hsa000400.62613330
65Salivary secretion_Homo sapiens_hsa049700.62462290
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.62228751
67Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.61872728
68Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.60842732
69Primary immunodeficiency_Homo sapiens_hsa053400.59765502
70Selenocompound metabolism_Homo sapiens_hsa004500.59153474
71Steroid biosynthesis_Homo sapiens_hsa001000.59104689
72Mineral absorption_Homo sapiens_hsa049780.58664189
73Glycerolipid metabolism_Homo sapiens_hsa005610.58030180
74Ether lipid metabolism_Homo sapiens_hsa005650.57617509
75Taste transduction_Homo sapiens_hsa047420.56401922
76Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.54528846
77Fatty acid degradation_Homo sapiens_hsa000710.54095014
78Ovarian steroidogenesis_Homo sapiens_hsa049130.54069842
79Regulation of autophagy_Homo sapiens_hsa041400.53692497
80Purine metabolism_Homo sapiens_hsa002300.52783538
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.52040561
82Allograft rejection_Homo sapiens_hsa053300.51820486
83Folate biosynthesis_Homo sapiens_hsa007900.49920576
84Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.48864075
85Circadian entrainment_Homo sapiens_hsa047130.47203922
86Synaptic vesicle cycle_Homo sapiens_hsa047210.46024540
87RNA transport_Homo sapiens_hsa030130.44972304
88Arginine and proline metabolism_Homo sapiens_hsa003300.44720574
89Cysteine and methionine metabolism_Homo sapiens_hsa002700.42589332
90Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.37820951
91Calcium signaling pathway_Homo sapiens_hsa040200.37726029
92Cholinergic synapse_Homo sapiens_hsa047250.36603103
93Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.36300181
94Rheumatoid arthritis_Homo sapiens_hsa053230.35900490
95Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.32341027
96Vitamin B6 metabolism_Homo sapiens_hsa007500.31044088
97Oxytocin signaling pathway_Homo sapiens_hsa049210.30423630
98cAMP signaling pathway_Homo sapiens_hsa040240.29472114
99Pyruvate metabolism_Homo sapiens_hsa006200.27657218
100Hippo signaling pathway_Homo sapiens_hsa043900.27644330

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »