

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of respiratory burst (GO:0060267) | 5.54377112 |
| 2 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 4.60092381 |
| 3 | protein prenylation (GO:0018342) | 4.58324393 |
| 4 | prenylation (GO:0097354) | 4.58324393 |
| 5 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.29517803 |
| 6 | cellular ketone body metabolic process (GO:0046950) | 4.27128793 |
| 7 | regulation of transmission of nerve impulse (GO:0051969) | 4.25885478 |
| 8 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.23193758 |
| 9 | NADH dehydrogenase complex assembly (GO:0010257) | 4.23193758 |
| 10 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.23193758 |
| 11 | mechanosensory behavior (GO:0007638) | 4.16104570 |
| 12 | diterpenoid biosynthetic process (GO:0016102) | 4.02177486 |
| 13 | protein complex biogenesis (GO:0070271) | 3.97595646 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.93210659 |
| 15 | neural tube formation (GO:0001841) | 3.89786476 |
| 16 | mitochondrial calcium ion homeostasis (GO:0051560) | 3.88041879 |
| 17 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 3.86076473 |
| 18 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.85345625 |
| 19 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.84470762 |
| 20 | termination of RNA polymerase III transcription (GO:0006386) | 3.84470762 |
| 21 | sphingomyelin metabolic process (GO:0006684) | 3.82775110 |
| 22 | protein neddylation (GO:0045116) | 3.77569346 |
| 23 | ketone body metabolic process (GO:1902224) | 3.75868619 |
| 24 | mitochondrial calcium ion transport (GO:0006851) | 3.74449494 |
| 25 | behavioral response to nicotine (GO:0035095) | 3.72736178 |
| 26 | terpenoid biosynthetic process (GO:0016114) | 3.71231587 |
| 27 | positive regulation of glycolytic process (GO:0045821) | 3.69139227 |
| 28 | signal peptide processing (GO:0006465) | 3.67958200 |
| 29 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.67845972 |
| 30 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 3.66563494 |
| 31 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 3.63965794 |
| 32 | negative regulation of T-helper cell differentiation (GO:0045623) | 3.63965794 |
| 33 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.55942549 |
| 34 | ATP synthesis coupled proton transport (GO:0015986) | 3.55942549 |
| 35 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.49200391 |
| 36 | regulation of immunoglobulin secretion (GO:0051023) | 3.48457001 |
| 37 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.47400219 |
| 38 | monoubiquitinated protein deubiquitination (GO:0035520) | 3.46834497 |
| 39 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.45724407 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.42462322 |
| 41 | auditory receptor cell differentiation (GO:0042491) | 3.42147165 |
| 42 | electron transport chain (GO:0022900) | 3.41740442 |
| 43 | protein heterotetramerization (GO:0051290) | 3.36145842 |
| 44 | endoderm formation (GO:0001706) | 3.34560570 |
| 45 | piRNA metabolic process (GO:0034587) | 3.30387204 |
| 46 | inner ear receptor cell differentiation (GO:0060113) | 3.24862034 |
| 47 | DNA deamination (GO:0045006) | 3.23570580 |
| 48 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.18043371 |
| 49 | detection of chemical stimulus involved in sensory perception of smell (GO:0050911) | 3.17393738 |
| 50 | positive regulation of fatty acid oxidation (GO:0046321) | 3.14613083 |
| 51 | mast cell activation involved in immune response (GO:0002279) | 3.10055103 |
| 52 | mast cell degranulation (GO:0043303) | 3.10055103 |
| 53 | icosanoid secretion (GO:0032309) | 3.09647508 |
| 54 | arachidonic acid secretion (GO:0050482) | 3.09647508 |
| 55 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.09053886 |
| 56 | exocrine pancreas development (GO:0031017) | 3.07603937 |
| 57 | proteasome assembly (GO:0043248) | 3.05276517 |
| 58 | protein K11-linked deubiquitination (GO:0035871) | 3.04689753 |
| 59 | rRNA methylation (GO:0031167) | 3.04159500 |
| 60 | keratinocyte development (GO:0003334) | 3.02788822 |
| 61 | rRNA modification (GO:0000154) | 3.01863998 |
| 62 | regulation of chronic inflammatory response (GO:0002676) | 2.99987651 |
| 63 | regulation of B cell receptor signaling pathway (GO:0050855) | 2.97338024 |
| 64 | DNA methylation involved in gamete generation (GO:0043046) | 2.91966612 |
| 65 | protein-cofactor linkage (GO:0018065) | 2.91681905 |
| 66 | hydrogen ion transmembrane transport (GO:1902600) | 2.87841903 |
| 67 | negative regulation of alpha-beta T cell differentiation (GO:0046639) | 2.86773916 |
| 68 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.85271673 |
| 69 | photoreceptor cell maintenance (GO:0045494) | 2.84874589 |
| 70 | positive regulation of granulocyte differentiation (GO:0030854) | 2.82414991 |
| 71 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.81772130 |
| 72 | ribosomal small subunit assembly (GO:0000028) | 2.75695213 |
| 73 | branched-chain amino acid catabolic process (GO:0009083) | 2.75325906 |
| 74 | drug catabolic process (GO:0042737) | 2.74647117 |
| 75 | proton transport (GO:0015992) | 2.73903187 |
| 76 | nonmotile primary cilium assembly (GO:0035058) | 2.73867434 |
| 77 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 2.73464997 |
| 78 | cell wall macromolecule catabolic process (GO:0016998) | 2.69501888 |
| 79 | regulation of cilium movement (GO:0003352) | 2.67805501 |
| 80 | hydrogen transport (GO:0006818) | 2.67209240 |
| 81 | glyoxylate metabolic process (GO:0046487) | 2.64748468 |
| 82 | intracellular protein transmembrane import (GO:0044743) | 2.63625486 |
| 83 | regulation of vitamin D biosynthetic process (GO:0060556) | 2.63624463 |
| 84 | epithelial cilium movement (GO:0003351) | 2.63301687 |
| 85 | oxidative demethylation (GO:0070989) | 2.62859153 |
| 86 | DNA double-strand break processing (GO:0000729) | 2.57575817 |
| 87 | metallo-sulfur cluster assembly (GO:0031163) | 2.56525430 |
| 88 | iron-sulfur cluster assembly (GO:0016226) | 2.56525430 |
| 89 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 2.55273348 |
| 90 | aldehyde catabolic process (GO:0046185) | 2.55121032 |
| 91 | indolalkylamine metabolic process (GO:0006586) | 2.54366013 |
| 92 | GTP biosynthetic process (GO:0006183) | 2.53966167 |
| 93 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.52815929 |
| 94 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.51428666 |
| 95 | N-terminal protein amino acid acetylation (GO:0006474) | 2.50461135 |
| 96 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 2.50029018 |
| 97 | fatty acid derivative transport (GO:1901571) | 2.49533230 |
| 98 | icosanoid transport (GO:0071715) | 2.49533230 |
| 99 | kinetochore assembly (GO:0051382) | 2.47235104 |
| 100 | respiratory chain complex IV assembly (GO:0008535) | 2.45983748 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VDR_22108803_ChIP-Seq_LS180_Human | 3.43168037 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.13364210 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.08338636 |
| 4 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 3.01982594 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.84758181 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.59432713 |
| 7 | EWS_26573619_Chip-Seq_HEK293_Human | 2.53724608 |
| 8 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.46250730 |
| 9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.42939905 |
| 10 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.35338347 |
| 11 | FUS_26573619_Chip-Seq_HEK293_Human | 2.34311015 |
| 12 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.30728365 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.25309809 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.18452796 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.16345352 |
| 16 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.16130912 |
| 17 | ER_23166858_ChIP-Seq_MCF-7_Human | 2.15445325 |
| 18 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.13709678 |
| 19 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.00103604 |
| 20 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.95677863 |
| 21 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.94506580 |
| 22 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.90327098 |
| 23 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.89549793 |
| 24 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.87595804 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.85623883 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.84924644 |
| 27 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.80382098 |
| 28 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.80223643 |
| 29 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.75521916 |
| 30 | P300_19829295_ChIP-Seq_ESCs_Human | 1.70805535 |
| 31 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.70519041 |
| 32 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.70469749 |
| 33 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.60789327 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.47942013 |
| 35 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.45575041 |
| 36 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.45575041 |
| 37 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.44991305 |
| 38 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.43595260 |
| 39 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.42606051 |
| 40 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.41872442 |
| 41 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.40260397 |
| 42 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.39261200 |
| 43 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.37959223 |
| 44 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.36804089 |
| 45 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.36102608 |
| 46 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.31054941 |
| 47 | AR_20517297_ChIP-Seq_VCAP_Human | 1.30678715 |
| 48 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.29952080 |
| 49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.28650951 |
| 50 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.28092814 |
| 51 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.25936692 |
| 52 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.22944922 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.22400694 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.22400694 |
| 55 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.19127056 |
| 56 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.18376809 |
| 57 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.18215714 |
| 58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.17588333 |
| 59 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.17076540 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.15617048 |
| 61 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.15487061 |
| 62 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.14565602 |
| 63 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.13101167 |
| 64 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12311917 |
| 65 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.12159536 |
| 66 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11661972 |
| 67 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11661972 |
| 68 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.11041210 |
| 69 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.10554206 |
| 70 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.10431603 |
| 71 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.09773099 |
| 72 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.09735710 |
| 73 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.09078480 |
| 74 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.09049457 |
| 75 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.08425587 |
| 76 | NFYB_21822215_ChIP-Seq_K562_Human | 1.08421039 |
| 77 | GATA3_26560356_Chip-Seq_TH2_Human | 1.08257353 |
| 78 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.08212521 |
| 79 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.07811673 |
| 80 | TBL1_22424771_ChIP-Seq_293T_Human | 1.07623844 |
| 81 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.06949284 |
| 82 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.06765154 |
| 83 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.05130208 |
| 84 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.04807942 |
| 85 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.04480218 |
| 86 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.04322563 |
| 87 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.04005213 |
| 88 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.03937801 |
| 89 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.03463294 |
| 90 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.03457355 |
| 91 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.02858185 |
| 92 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.01931495 |
| 93 | NFYA_21822215_ChIP-Seq_K562_Human | 1.01521139 |
| 94 | TCF4_23295773_ChIP-Seq_U87_Human | 1.00608404 |
| 95 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.00225051 |
| 96 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.99800839 |
| 97 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.99751627 |
| 98 | AR_25329375_ChIP-Seq_VCAP_Human | 0.99124848 |
| 99 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.98869914 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.98234691 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005084_abnormal_gallbladder_morpholo | 3.69661645 |
| 2 | MP0001873_stomach_inflammation | 3.43398679 |
| 3 | MP0003646_muscle_fatigue | 3.33339944 |
| 4 | MP0001485_abnormal_pinna_reflex | 3.30061706 |
| 5 | MP0004742_abnormal_vestibular_system | 3.00933548 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.77813578 |
| 7 | MP0005670_abnormal_white_adipose | 2.73969504 |
| 8 | MP0006292_abnormal_olfactory_placode | 2.64176928 |
| 9 | MP0005451_abnormal_body_composition | 2.38021537 |
| 10 | MP0000427_abnormal_hair_cycle | 2.37405076 |
| 11 | MP0003283_abnormal_digestive_organ | 2.21307245 |
| 12 | MP0005365_abnormal_bile_salt | 2.12757012 |
| 13 | MP0005551_abnormal_eye_electrophysiolog | 2.11166179 |
| 14 | MP0001486_abnormal_startle_reflex | 2.06332993 |
| 15 | MP0001764_abnormal_homeostasis | 1.78619397 |
| 16 | MP0008872_abnormal_physiological_respon | 1.76955570 |
| 17 | MP0004043_abnormal_pH_regulation | 1.75997118 |
| 18 | MP0002736_abnormal_nociception_after | 1.75736993 |
| 19 | MP0005671_abnormal_response_to | 1.69135497 |
| 20 | MP0004142_abnormal_muscle_tone | 1.68312145 |
| 21 | MP0006072_abnormal_retinal_apoptosis | 1.66802337 |
| 22 | MP0002653_abnormal_ependyma_morphology | 1.66258433 |
| 23 | MP0004885_abnormal_endolymph | 1.61027606 |
| 24 | MP0004019_abnormal_vitamin_homeostasis | 1.58986301 |
| 25 | MP0001348_abnormal_lacrimal_gland | 1.58277271 |
| 26 | MP0003119_abnormal_digestive_system | 1.56701047 |
| 27 | MP0001293_anophthalmia | 1.54077081 |
| 28 | MP0006036_abnormal_mitochondrial_physio | 1.51112021 |
| 29 | MP0003763_abnormal_thymus_physiology | 1.44439947 |
| 30 | MP0008877_abnormal_DNA_methylation | 1.43141193 |
| 31 | MP0006035_abnormal_mitochondrial_morpho | 1.41050759 |
| 32 | MP0002009_preneoplasia | 1.39638247 |
| 33 | MP0008057_abnormal_DNA_replication | 1.39342752 |
| 34 | MP0002166_altered_tumor_susceptibility | 1.39116037 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.38453948 |
| 36 | MP0005646_abnormal_pituitary_gland | 1.33201942 |
| 37 | MP0002234_abnormal_pharynx_morphology | 1.29574410 |
| 38 | MP0000685_abnormal_immune_system | 1.28728784 |
| 39 | MP0002254_reproductive_system_inflammat | 1.25568512 |
| 40 | MP0008058_abnormal_DNA_repair | 1.24917138 |
| 41 | MP0010386_abnormal_urinary_bladder | 1.24091826 |
| 42 | MP0002160_abnormal_reproductive_system | 1.23658817 |
| 43 | MP0001756_abnormal_urination | 1.20894942 |
| 44 | MP0003718_maternal_effect | 1.16312651 |
| 45 | MP0005389_reproductive_system_phenotype | 1.16212486 |
| 46 | MP0003786_premature_aging | 1.15187311 |
| 47 | MP0003195_calcinosis | 1.14772926 |
| 48 | MP0003938_abnormal_ear_development | 1.13685081 |
| 49 | MP0005410_abnormal_fertilization | 1.13070676 |
| 50 | MP0001835_abnormal_antigen_presentation | 1.12750827 |
| 51 | MP0006276_abnormal_autonomic_nervous | 1.12390627 |
| 52 | MP0005645_abnormal_hypothalamus_physiol | 1.10537087 |
| 53 | MP0005448_abnormal_energy_balance | 1.10522595 |
| 54 | MP0002102_abnormal_ear_morphology | 1.09929035 |
| 55 | MP0005310_abnormal_salivary_gland | 1.08121088 |
| 56 | MP0001501_abnormal_sleep_pattern | 1.07852073 |
| 57 | MP0001529_abnormal_vocalization | 1.06789811 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.06254671 |
| 59 | MP0001968_abnormal_touch/_nociception | 1.05299730 |
| 60 | MP0003252_abnormal_bile_duct | 1.04384698 |
| 61 | MP0004133_heterotaxia | 1.02150787 |
| 62 | MP0003878_abnormal_ear_physiology | 1.01703458 |
| 63 | MP0005377_hearing/vestibular/ear_phenot | 1.01703458 |
| 64 | MP0005253_abnormal_eye_physiology | 1.00474557 |
| 65 | MP0002006_tumorigenesis | 0.96194719 |
| 66 | MP0003937_abnormal_limbs/digits/tail_de | 0.93986501 |
| 67 | MP0003638_abnormal_response/metabolism_ | 0.93042411 |
| 68 | MP0001663_abnormal_digestive_system | 0.92393889 |
| 69 | MP0000631_abnormal_neuroendocrine_gland | 0.91783501 |
| 70 | MP0001800_abnormal_humoral_immune | 0.90549497 |
| 71 | MP0002909_abnormal_adrenal_gland | 0.90508304 |
| 72 | MP0005386_behavior/neurological_phenoty | 0.89065769 |
| 73 | MP0004924_abnormal_behavior | 0.89065769 |
| 74 | MP0002837_dystrophic_cardiac_calcinosis | 0.87064763 |
| 75 | MP0003787_abnormal_imprinting | 0.86556488 |
| 76 | MP0001919_abnormal_reproductive_system | 0.85654670 |
| 77 | MP0003828_pulmonary_edema | 0.85383663 |
| 78 | MP0002735_abnormal_chemical_nociception | 0.82958621 |
| 79 | MP0008995_early_reproductive_senescence | 0.82164727 |
| 80 | MP0002693_abnormal_pancreas_physiology | 0.82140023 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.81555721 |
| 82 | MP0002233_abnormal_nose_morphology | 0.79874402 |
| 83 | MP0009764_decreased_sensitivity_to | 0.79644958 |
| 84 | MP0009046_muscle_twitch | 0.79317837 |
| 85 | MP0001929_abnormal_gametogenesis | 0.77722807 |
| 86 | MP0001984_abnormal_olfaction | 0.77455379 |
| 87 | MP0005408_hypopigmentation | 0.76751975 |
| 88 | MP0002396_abnormal_hematopoietic_system | 0.75910129 |
| 89 | MP0010094_abnormal_chromosome_stability | 0.74566370 |
| 90 | MP0001944_abnormal_pancreas_morphology | 0.73501028 |
| 91 | MP0003880_abnormal_central_pattern | 0.72349146 |
| 92 | MP0002277_abnormal_respiratory_mucosa | 0.72019318 |
| 93 | MP0003698_abnormal_male_reproductive | 0.71848015 |
| 94 | MP0000470_abnormal_stomach_morphology | 0.70602295 |
| 95 | MP0009115_abnormal_fat_cell | 0.69808092 |
| 96 | MP0009643_abnormal_urine_homeostasis | 0.68867608 |
| 97 | MP0001790_abnormal_immune_system | 0.68222701 |
| 98 | MP0005387_immune_system_phenotype | 0.68222701 |
| 99 | MP0001145_abnormal_male_reproductive | 0.68198819 |
| 100 | MP0002210_abnormal_sex_determination | 0.66356193 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Pancreatic islet-cell hyperplasia (HP:0004510) | 5.25895346 |
| 2 | Stomatitis (HP:0010280) | 4.71903920 |
| 3 | Congenital, generalized hypertrichosis (HP:0004540) | 4.61154974 |
| 4 | Hypoglycemic seizures (HP:0002173) | 4.10938178 |
| 5 | Pendular nystagmus (HP:0012043) | 4.06171787 |
| 6 | Hyperinsulinemic hypoglycemia (HP:0000825) | 3.89689597 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.78010688 |
| 8 | Pancreatic cysts (HP:0001737) | 3.55652368 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.50602137 |
| 10 | Abnormality of midbrain morphology (HP:0002418) | 3.50602137 |
| 11 | Enlarged penis (HP:0000040) | 3.49255165 |
| 12 | Type II lissencephaly (HP:0007260) | 3.32870561 |
| 13 | IgG deficiency (HP:0004315) | 3.29016616 |
| 14 | Decreased central vision (HP:0007663) | 3.20250673 |
| 15 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.19653345 |
| 16 | Attenuation of retinal blood vessels (HP:0007843) | 3.18518413 |
| 17 | Hypoglycemic coma (HP:0001325) | 3.17477281 |
| 18 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.03632461 |
| 19 | Increased IgM level (HP:0003496) | 3.02276748 |
| 20 | Cerebellar dysplasia (HP:0007033) | 3.01178048 |
| 21 | Long foot (HP:0001833) | 3.00132618 |
| 22 | Febrile seizures (HP:0002373) | 2.86368438 |
| 23 | B lymphocytopenia (HP:0010976) | 2.80522434 |
| 24 | Congenital stationary night blindness (HP:0007642) | 2.80091247 |
| 25 | Neuroendocrine neoplasm (HP:0100634) | 2.79632799 |
| 26 | Keratoconus (HP:0000563) | 2.78198063 |
| 27 | Increased corneal curvature (HP:0100692) | 2.78198063 |
| 28 | Pheochromocytoma (HP:0002666) | 2.76511467 |
| 29 | Symptomatic seizures (HP:0011145) | 2.65837330 |
| 30 | Acute necrotizing encephalopathy (HP:0006965) | 2.65829712 |
| 31 | Abnormality of B cell number (HP:0010975) | 2.62008779 |
| 32 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.59754696 |
| 33 | Abnormality of alanine metabolism (HP:0010916) | 2.59754696 |
| 34 | Hyperalaninemia (HP:0003348) | 2.59754696 |
| 35 | Ketoacidosis (HP:0001993) | 2.59502993 |
| 36 | Acute encephalopathy (HP:0006846) | 2.58954285 |
| 37 | Clitoromegaly (HP:0000057) | 2.55573113 |
| 38 | Abnormality of endocrine pancreas physiology (HP:0012093) | 2.55058324 |
| 39 | Abnormality of the pancreatic islet cells (HP:0006476) | 2.55058324 |
| 40 | Optic disc pallor (HP:0000543) | 2.52075269 |
| 41 | Progressive macrocephaly (HP:0004481) | 2.48163907 |
| 42 | True hermaphroditism (HP:0010459) | 2.42073218 |
| 43 | Medial flaring of the eyebrow (HP:0010747) | 2.40272641 |
| 44 | Abnormality of the ileum (HP:0001549) | 2.35101255 |
| 45 | Chronic bronchitis (HP:0004469) | 2.35070569 |
| 46 | Abolished electroretinogram (ERG) (HP:0000550) | 2.34815157 |
| 47 | Pancreatic fibrosis (HP:0100732) | 2.33424567 |
| 48 | Cerebral hemorrhage (HP:0001342) | 2.33280912 |
| 49 | Nephronophthisis (HP:0000090) | 2.26841789 |
| 50 | Reticulocytopenia (HP:0001896) | 2.22067092 |
| 51 | Clubbing of toes (HP:0100760) | 2.17010262 |
| 52 | Ectopic kidney (HP:0000086) | 2.15821742 |
| 53 | Thick nail (HP:0001805) | 2.13448788 |
| 54 | Meckel diverticulum (HP:0002245) | 2.13409481 |
| 55 | Ketosis (HP:0001946) | 2.13381759 |
| 56 | Fatigue (HP:0012378) | 2.13347855 |
| 57 | Colon cancer (HP:0003003) | 2.11796592 |
| 58 | Female pseudohermaphroditism (HP:0010458) | 2.08441862 |
| 59 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.06579604 |
| 60 | Absent/shortened dynein arms (HP:0200106) | 2.06579604 |
| 61 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.04651321 |
| 62 | Acute myeloid leukemia (HP:0004808) | 2.03452110 |
| 63 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.01534417 |
| 64 | Increased CSF lactate (HP:0002490) | 1.99049839 |
| 65 | Abnormal mitochondria in muscle tissue (HP:0008316) | 1.95996017 |
| 66 | Hyperglycemia (HP:0003074) | 1.95304455 |
| 67 | Bifid tongue (HP:0010297) | 1.95245886 |
| 68 | Mitochondrial inheritance (HP:0001427) | 1.94328347 |
| 69 | Genital tract atresia (HP:0001827) | 1.94313024 |
| 70 | Insulin-resistant diabetes mellitus (HP:0000831) | 1.94129237 |
| 71 | Vaginal atresia (HP:0000148) | 1.94091475 |
| 72 | Chorioretinal atrophy (HP:0000533) | 1.94028377 |
| 73 | Cellular immunodeficiency (HP:0005374) | 1.90846784 |
| 74 | Aplastic anemia (HP:0001915) | 1.89480407 |
| 75 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.89228748 |
| 76 | Abnormal lung lobation (HP:0002101) | 1.88074534 |
| 77 | Lethargy (HP:0001254) | 1.88000515 |
| 78 | Hypoplasia of the thymus (HP:0000778) | 1.87986878 |
| 79 | Chromsome breakage (HP:0040012) | 1.87890164 |
| 80 | Abnormality of chromosome stability (HP:0003220) | 1.87603119 |
| 81 | Homocystinuria (HP:0002156) | 1.87448398 |
| 82 | Abnormality of homocysteine metabolism (HP:0010919) | 1.87448398 |
| 83 | Abnormality of the renal medulla (HP:0100957) | 1.87418135 |
| 84 | Impulsivity (HP:0100710) | 1.85953910 |
| 85 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.85537108 |
| 86 | Abnormality of the prostate (HP:0008775) | 1.81857047 |
| 87 | Gaze-evoked nystagmus (HP:0000640) | 1.79836460 |
| 88 | Pancytopenia (HP:0001876) | 1.79539558 |
| 89 | Lissencephaly (HP:0001339) | 1.77923782 |
| 90 | Poor coordination (HP:0002370) | 1.77243050 |
| 91 | Bilateral microphthalmos (HP:0007633) | 1.76713059 |
| 92 | Methylmalonic aciduria (HP:0012120) | 1.76539066 |
| 93 | Methylmalonic acidemia (HP:0002912) | 1.76485021 |
| 94 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.76365691 |
| 95 | Absent thumb (HP:0009777) | 1.75708710 |
| 96 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.74185657 |
| 97 | Asplenia (HP:0001746) | 1.73400671 |
| 98 | Cerebral edema (HP:0002181) | 1.71867302 |
| 99 | Abnormality of the preputium (HP:0100587) | 1.71552025 |
| 100 | Hyperglycinemia (HP:0002154) | 1.70762893 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | INSRR | 8.08894023 |
| 2 | FRK | 4.90028423 |
| 3 | NUAK1 | 3.59867387 |
| 4 | CASK | 3.09715262 |
| 5 | MKNK1 | 2.72443587 |
| 6 | WNK3 | 2.48344683 |
| 7 | PDK2 | 2.24254504 |
| 8 | MAP4K2 | 2.24068462 |
| 9 | ZAK | 2.16696963 |
| 10 | TAF1 | 2.10230962 |
| 11 | TNIK | 1.97855253 |
| 12 | SIK2 | 1.85389408 |
| 13 | VRK2 | 1.83038774 |
| 14 | MST4 | 1.77574241 |
| 15 | TAOK3 | 1.68168097 |
| 16 | PBK | 1.64605971 |
| 17 | PIK3CG | 1.63174755 |
| 18 | MAPKAPK5 | 1.58664858 |
| 19 | TLK1 | 1.49161526 |
| 20 | MKNK2 | 1.43186444 |
| 21 | BMPR2 | 1.34970860 |
| 22 | BRSK2 | 1.30690266 |
| 23 | ADRBK2 | 1.23686488 |
| 24 | NEK2 | 1.23617282 |
| 25 | EIF2AK3 | 1.22709073 |
| 26 | LATS1 | 1.22048420 |
| 27 | EPHA3 | 1.21416033 |
| 28 | STK38L | 1.13341177 |
| 29 | GRK1 | 1.12951313 |
| 30 | NLK | 1.06341561 |
| 31 | TEC | 1.04569717 |
| 32 | VRK1 | 1.04123545 |
| 33 | CDC7 | 1.01792120 |
| 34 | STK39 | 1.01712447 |
| 35 | AKT3 | 1.00506352 |
| 36 | BRD4 | 0.99908719 |
| 37 | NME1 | 0.99348308 |
| 38 | OXSR1 | 0.97640474 |
| 39 | MAP3K9 | 0.97469831 |
| 40 | TNK2 | 0.93331625 |
| 41 | EIF2AK1 | 0.92375660 |
| 42 | PLK4 | 0.91158159 |
| 43 | STK38 | 0.87193664 |
| 44 | STK3 | 0.86397920 |
| 45 | BCKDK | 0.85900679 |
| 46 | EIF2AK2 | 0.85154761 |
| 47 | ACVR1B | 0.83319450 |
| 48 | RPS6KA5 | 0.82449863 |
| 49 | NEK6 | 0.80849909 |
| 50 | CAMKK2 | 0.78880013 |
| 51 | PLK2 | 0.77205742 |
| 52 | NME2 | 0.76878320 |
| 53 | ITK | 0.75544917 |
| 54 | WNK4 | 0.75292768 |
| 55 | BMPR1B | 0.72925027 |
| 56 | PINK1 | 0.70768039 |
| 57 | STK4 | 0.70254261 |
| 58 | BUB1 | 0.67146131 |
| 59 | FLT3 | 0.65358406 |
| 60 | ADRBK1 | 0.62723780 |
| 61 | IRAK1 | 0.62471728 |
| 62 | LYN | 0.61205490 |
| 63 | TIE1 | 0.56234420 |
| 64 | PIK3CA | 0.54772925 |
| 65 | TRIM28 | 0.51027639 |
| 66 | IKBKB | 0.50357610 |
| 67 | FER | 0.49596769 |
| 68 | TXK | 0.48735395 |
| 69 | DAPK2 | 0.48403329 |
| 70 | BLK | 0.47521316 |
| 71 | FES | 0.41819331 |
| 72 | PTK2B | 0.41335805 |
| 73 | DYRK1A | 0.41074633 |
| 74 | PRKAA2 | 0.39161400 |
| 75 | SYK | 0.37602199 |
| 76 | BRSK1 | 0.37399358 |
| 77 | TGFBR2 | 0.37188925 |
| 78 | CAMK1 | 0.37021032 |
| 79 | FGFR2 | 0.36234620 |
| 80 | PLK3 | 0.34921325 |
| 81 | WEE1 | 0.32178999 |
| 82 | CDK8 | 0.31388895 |
| 83 | IGF1R | 0.30423331 |
| 84 | CAMK4 | 0.28706514 |
| 85 | MAP4K1 | 0.27446820 |
| 86 | FGFR1 | 0.27393940 |
| 87 | CSNK1A1 | 0.27207673 |
| 88 | INSR | 0.25953974 |
| 89 | DYRK2 | 0.25037719 |
| 90 | SGK2 | 0.24210307 |
| 91 | GRK6 | 0.23146749 |
| 92 | PRKCH | 0.22352156 |
| 93 | PRKCA | 0.21207396 |
| 94 | GRK5 | 0.21183899 |
| 95 | TSSK6 | 0.21010058 |
| 96 | DAPK3 | 0.20733059 |
| 97 | PRKCE | 0.19873127 |
| 98 | PRKCG | 0.19846789 |
| 99 | EPHA4 | 0.19560874 |
| 100 | PRKCQ | 0.19185818 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.41230898 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.36938644 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.10624194 |
| 4 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.86493775 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 2.85767108 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.83353965 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.75957823 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.64881221 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50853536 |
| 10 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.26049759 |
| 11 | Ribosome_Homo sapiens_hsa03010 | 2.24527537 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.24079386 |
| 13 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.21169760 |
| 14 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.97715493 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.95446093 |
| 16 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.83716855 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.79740478 |
| 18 | Huntingtons disease_Homo sapiens_hsa05016 | 1.79535124 |
| 19 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.71034727 |
| 20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.69465756 |
| 21 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.68972476 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.68017917 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.67537582 |
| 24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.64447766 |
| 25 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.50905849 |
| 26 | Olfactory transduction_Homo sapiens_hsa04740 | 1.41677116 |
| 27 | Basal transcription factors_Homo sapiens_hsa03022 | 1.39883640 |
| 28 | Phototransduction_Homo sapiens_hsa04744 | 1.39084770 |
| 29 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.37420764 |
| 30 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.34623716 |
| 31 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.34027089 |
| 32 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.25852860 |
| 33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.21596043 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.20255066 |
| 35 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.19306199 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.17947331 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.17096687 |
| 38 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.12513515 |
| 39 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.11315332 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.10148970 |
| 41 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.08475286 |
| 42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.08023004 |
| 43 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.03397392 |
| 44 | Taste transduction_Homo sapiens_hsa04742 | 1.02344939 |
| 45 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.00917400 |
| 46 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.95563126 |
| 47 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.95402774 |
| 48 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.94612004 |
| 49 | Peroxisome_Homo sapiens_hsa04146 | 0.92568170 |
| 50 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.91318318 |
| 51 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.88488039 |
| 52 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.88023995 |
| 53 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.87142252 |
| 54 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.85275199 |
| 55 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.82869837 |
| 56 | Nicotine addiction_Homo sapiens_hsa05033 | 0.81470129 |
| 57 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.79786470 |
| 58 | Purine metabolism_Homo sapiens_hsa00230 | 0.79641278 |
| 59 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.79387218 |
| 60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.73470840 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.72354946 |
| 62 | Mismatch repair_Homo sapiens_hsa03430 | 0.71467823 |
| 63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70524183 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70520486 |
| 65 | RNA transport_Homo sapiens_hsa03013 | 0.69052067 |
| 66 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.67474846 |
| 67 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.65619540 |
| 68 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.59047969 |
| 69 | Mineral absorption_Homo sapiens_hsa04978 | 0.58487720 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.57692709 |
| 71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.55394427 |
| 72 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55337998 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54211008 |
| 74 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54069749 |
| 75 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.53843342 |
| 76 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.53000952 |
| 77 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.52528895 |
| 78 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.50981285 |
| 79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47927453 |
| 80 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.45297667 |
| 81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.43521342 |
| 82 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42400515 |
| 83 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41470872 |
| 84 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39198300 |
| 85 | DNA replication_Homo sapiens_hsa03030 | 0.36762328 |
| 86 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.35973062 |
| 87 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.35486172 |
| 88 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.34128581 |
| 89 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.32015843 |
| 90 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.29713499 |
| 91 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.29354225 |
| 92 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.29246723 |
| 93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.28697094 |
| 94 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.27721010 |
| 95 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.24432929 |
| 96 | Histidine metabolism_Homo sapiens_hsa00340 | 0.22252208 |
| 97 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.22187622 |
| 98 | Sulfur relay system_Homo sapiens_hsa04122 | 0.21125421 |
| 99 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.20675794 |
| 100 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.20247365 |

