

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 9.54835820 |
| 2 | viral transcription (GO:0019083) | 7.55630267 |
| 3 | translational termination (GO:0006415) | 7.12303649 |
| 4 | ribosomal small subunit biogenesis (GO:0042274) | 6.53092900 |
| 5 | ribosomal small subunit assembly (GO:0000028) | 6.23139209 |
| 6 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 6.12372657 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.04615698 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.98604976 |
| 9 | protein targeting to ER (GO:0045047) | 5.94458981 |
| 10 | translational elongation (GO:0006414) | 5.94059810 |
| 11 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.81079463 |
| 12 | protein localization to endoplasmic reticulum (GO:0070972) | 5.54213555 |
| 13 | viral life cycle (GO:0019058) | 5.52253108 |
| 14 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 5.39430577 |
| 15 | cellular protein complex disassembly (GO:0043624) | 5.27172837 |
| 16 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.01144981 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.63058521 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 4.63058521 |
| 19 | translational initiation (GO:0006413) | 4.54460016 |
| 20 | ribosomal large subunit biogenesis (GO:0042273) | 4.52721776 |
| 21 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.48709553 |
| 22 | behavioral response to nicotine (GO:0035095) | 4.36905881 |
| 23 | piRNA metabolic process (GO:0034587) | 4.35922768 |
| 24 | protein complex disassembly (GO:0043241) | 4.33637490 |
| 25 | macromolecular complex disassembly (GO:0032984) | 4.22964182 |
| 26 | oxygen transport (GO:0015671) | 4.13231940 |
| 27 | negative regulation of B cell apoptotic process (GO:0002903) | 4.11849389 |
| 28 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.00984136 |
| 29 | protein targeting to membrane (GO:0006612) | 3.95016092 |
| 30 | positive regulation of fatty acid transport (GO:2000193) | 3.94459656 |
| 31 | S-adenosylmethionine metabolic process (GO:0046500) | 3.83853285 |
| 32 | positive regulation of prostaglandin secretion (GO:0032308) | 3.68155221 |
| 33 | DNA deamination (GO:0045006) | 3.67849758 |
| 34 | translation (GO:0006412) | 3.66794488 |
| 35 | rRNA catabolic process (GO:0016075) | 3.62366459 |
| 36 | cell wall macromolecule catabolic process (GO:0016998) | 3.55008790 |
| 37 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.53614327 |
| 38 | nonmotile primary cilium assembly (GO:0035058) | 3.50023978 |
| 39 | homocysteine metabolic process (GO:0050667) | 3.49271888 |
| 40 | DNA methylation involved in gamete generation (GO:0043046) | 3.49123300 |
| 41 | gas transport (GO:0015669) | 3.49047356 |
| 42 | positive regulation of interleukin-17 production (GO:0032740) | 3.48920539 |
| 43 | regulation of regulatory T cell differentiation (GO:0045589) | 3.46097628 |
| 44 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.41262440 |
| 45 | aggressive behavior (GO:0002118) | 3.35900722 |
| 46 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.35430954 |
| 47 | mRNA catabolic process (GO:0006402) | 3.35003710 |
| 48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.34334304 |
| 49 | motile cilium assembly (GO:0044458) | 3.27217087 |
| 50 | positive regulation of icosanoid secretion (GO:0032305) | 3.21759285 |
| 51 | chaperone-mediated protein transport (GO:0072321) | 3.21041205 |
| 52 | cellular response to interferon-beta (GO:0035458) | 3.14563738 |
| 53 | positive regulation of activated T cell proliferation (GO:0042104) | 3.13176887 |
| 54 | regulation of prostaglandin secretion (GO:0032306) | 3.08788292 |
| 55 | organelle disassembly (GO:1903008) | 3.00351034 |
| 56 | mannosylation (GO:0097502) | 2.97729387 |
| 57 | male meiosis (GO:0007140) | 2.96216104 |
| 58 | cell wall macromolecule metabolic process (GO:0044036) | 2.95932742 |
| 59 | ATP biosynthetic process (GO:0006754) | 2.95550611 |
| 60 | regulation of B cell apoptotic process (GO:0002902) | 2.94137213 |
| 61 | regulation of immunoglobulin secretion (GO:0051023) | 2.94129512 |
| 62 | RNA catabolic process (GO:0006401) | 2.93719374 |
| 63 | positive regulation of T cell apoptotic process (GO:0070234) | 2.93688072 |
| 64 | myoblast migration (GO:0051451) | 2.93662256 |
| 65 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.89809885 |
| 66 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.89751603 |
| 67 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.89696959 |
| 68 | positive regulation of isotype switching (GO:0045830) | 2.89474889 |
| 69 | embryonic hemopoiesis (GO:0035162) | 2.89215063 |
| 70 | resolution of meiotic recombination intermediates (GO:0000712) | 2.85600482 |
| 71 | substrate-independent telencephalic tangential migration (GO:0021826) | 2.85043930 |
| 72 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 2.85043930 |
| 73 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.84198020 |
| 74 | ribonucleoprotein complex disassembly (GO:0032988) | 2.83143842 |
| 75 | cellular biogenic amine catabolic process (GO:0042402) | 2.83068720 |
| 76 | amine catabolic process (GO:0009310) | 2.83068720 |
| 77 | indolalkylamine metabolic process (GO:0006586) | 2.82659929 |
| 78 | nucleotide transmembrane transport (GO:1901679) | 2.81034854 |
| 79 | interferon-gamma production (GO:0032609) | 2.80194900 |
| 80 | cellular component biogenesis (GO:0044085) | 2.76807031 |
| 81 | rRNA processing (GO:0006364) | 2.76027682 |
| 82 | positive regulation of DNA recombination (GO:0045911) | 2.75442679 |
| 83 | positive regulation of catecholamine secretion (GO:0033605) | 2.75397162 |
| 84 | rRNA metabolic process (GO:0016072) | 2.74878810 |
| 85 | somite development (GO:0061053) | 2.71910854 |
| 86 | regulation of female receptivity (GO:0045924) | 2.70709054 |
| 87 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.70638947 |
| 88 | establishment of protein localization to membrane (GO:0090150) | 2.69123455 |
| 89 | pseudouridine synthesis (GO:0001522) | 2.68225049 |
| 90 | response to interferon-beta (GO:0035456) | 2.66361438 |
| 91 | positive regulation of defense response to virus by host (GO:0002230) | 2.65333194 |
| 92 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 2.64964709 |
| 93 | peptidyl-histidine modification (GO:0018202) | 2.63448101 |
| 94 | viral protein processing (GO:0019082) | 2.62153558 |
| 95 | GPI anchor metabolic process (GO:0006505) | 2.61934861 |
| 96 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 2.59564362 |
| 97 | cytidine metabolic process (GO:0046087) | 2.57724948 |
| 98 | cytidine catabolic process (GO:0006216) | 2.57724948 |
| 99 | cytidine deamination (GO:0009972) | 2.57724948 |
| 100 | negative regulation of macrophage differentiation (GO:0045650) | 2.56444723 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.66033286 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.23733596 |
| 3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.22042026 |
| 4 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.09131918 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.61818032 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.52541629 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.40338945 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.28578914 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.12889973 |
| 10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.02498194 |
| 11 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 2.01326074 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.97683837 |
| 13 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.91017018 |
| 14 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.89892078 |
| 15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.88478912 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.84360025 |
| 17 | EWS_26573619_Chip-Seq_HEK293_Human | 1.83581354 |
| 18 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.75646425 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.72911909 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.71444969 |
| 21 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.55437451 |
| 22 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.55272359 |
| 23 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.53898515 |
| 24 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.53490488 |
| 25 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.51323816 |
| 26 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.51091618 |
| 27 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.49123714 |
| 28 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.45763230 |
| 29 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.44956170 |
| 30 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.44956170 |
| 31 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.44778575 |
| 32 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.44324080 |
| 33 | NCOR_22424771_ChIP-Seq_293T_Human | 1.42144433 |
| 34 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.42023981 |
| 35 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.41696315 |
| 36 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.41044341 |
| 37 | FUS_26573619_Chip-Seq_HEK293_Human | 1.40429192 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.37262614 |
| 39 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.36383451 |
| 40 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.36336094 |
| 41 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.35186601 |
| 42 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.35117315 |
| 43 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.34606418 |
| 44 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34185844 |
| 45 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.32955555 |
| 46 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.32090454 |
| 47 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.30488256 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30212420 |
| 49 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.28483792 |
| 50 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.28483792 |
| 51 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.27386608 |
| 52 | ERA_21632823_ChIP-Seq_H3396_Human | 1.26901942 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.24599719 |
| 54 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.23991387 |
| 55 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.23488491 |
| 56 | P300_19829295_ChIP-Seq_ESCs_Human | 1.22345013 |
| 57 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.18649269 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.18454256 |
| 59 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.18206356 |
| 60 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.17696785 |
| 61 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.15975836 |
| 62 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.15907861 |
| 63 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.15017504 |
| 64 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.14104679 |
| 65 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.14034925 |
| 66 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.13791489 |
| 67 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.12163396 |
| 68 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.11551813 |
| 69 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.09044896 |
| 70 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.08496552 |
| 71 | RBPJ_21746931_ChIP-Seq_IB4_Human | 1.07979625 |
| 72 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.07554649 |
| 73 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 1.06535235 |
| 74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06500336 |
| 75 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.06289212 |
| 76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.05606557 |
| 77 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.05502902 |
| 78 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.05344952 |
| 79 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.02504512 |
| 80 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01022363 |
| 81 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.00081608 |
| 82 | NFYB_21822215_ChIP-Seq_K562_Human | 0.99709556 |
| 83 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99182609 |
| 84 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.98071347 |
| 85 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.96415736 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.94972874 |
| 87 | NFYA_21822215_ChIP-Seq_K562_Human | 0.94578079 |
| 88 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.94017770 |
| 89 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.93923480 |
| 90 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.93709645 |
| 91 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93707325 |
| 92 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.92571424 |
| 93 | SA1_27219007_Chip-Seq_Bcells_Human | 0.92119752 |
| 94 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.92002589 |
| 95 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.91514246 |
| 96 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.90620879 |
| 97 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.90598881 |
| 98 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.90344685 |
| 99 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.89821464 |
| 100 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 0.89753573 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.38769929 |
| 2 | MP0003878_abnormal_ear_physiology | 3.58828136 |
| 3 | MP0005377_hearing/vestibular/ear_phenot | 3.58828136 |
| 4 | MP0003787_abnormal_imprinting | 3.48662984 |
| 5 | MP0006292_abnormal_olfactory_placode | 3.14252889 |
| 6 | MP0004147_increased_porphyrin_level | 3.07005294 |
| 7 | MP0004885_abnormal_endolymph | 3.03672424 |
| 8 | MP0003011_delayed_dark_adaptation | 2.78738449 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.75488356 |
| 10 | MP0004142_abnormal_muscle_tone | 2.65340970 |
| 11 | MP0003646_muscle_fatigue | 2.42642747 |
| 12 | MP0001440_abnormal_grooming_behavior | 2.26174012 |
| 13 | MP0004742_abnormal_vestibular_system | 2.15792189 |
| 14 | MP0001968_abnormal_touch/_nociception | 2.09443956 |
| 15 | MP0003300_gastrointestinal_ulcer | 2.03483232 |
| 16 | MP0006276_abnormal_autonomic_nervous | 1.95674196 |
| 17 | MP0004019_abnormal_vitamin_homeostasis | 1.91393962 |
| 18 | MP0008875_abnormal_xenobiotic_pharmacok | 1.89831257 |
| 19 | MP0002736_abnormal_nociception_after | 1.89209734 |
| 20 | MP0001986_abnormal_taste_sensitivity | 1.87037717 |
| 21 | MP0003879_abnormal_hair_cell | 1.84311235 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.70856540 |
| 23 | MP0000015_abnormal_ear_pigmentation | 1.64122592 |
| 24 | MP0001502_abnormal_circadian_rhythm | 1.63127941 |
| 25 | MP0008872_abnormal_physiological_respon | 1.60294246 |
| 26 | MP0001853_heart_inflammation | 1.58712344 |
| 27 | MP0000427_abnormal_hair_cycle | 1.57317296 |
| 28 | MP0002095_abnormal_skin_pigmentation | 1.50106698 |
| 29 | MP0009046_muscle_twitch | 1.49618520 |
| 30 | MP0003186_abnormal_redox_activity | 1.48495082 |
| 31 | MP0006035_abnormal_mitochondrial_morpho | 1.47178500 |
| 32 | MP0003121_genomic_imprinting | 1.41545780 |
| 33 | MP0001293_anophthalmia | 1.38272176 |
| 34 | MP0001984_abnormal_olfaction | 1.38007995 |
| 35 | MP0002234_abnormal_pharynx_morphology | 1.31329058 |
| 36 | MP0003718_maternal_effect | 1.30595428 |
| 37 | MP0002272_abnormal_nervous_system | 1.30384175 |
| 38 | MP0004133_heterotaxia | 1.26234187 |
| 39 | MP0005551_abnormal_eye_electrophysiolog | 1.25811550 |
| 40 | MP0000604_amyloidosis | 1.25134346 |
| 41 | MP0001835_abnormal_antigen_presentation | 1.23817166 |
| 42 | MP0009764_decreased_sensitivity_to | 1.23233794 |
| 43 | MP0003866_abnormal_defecation | 1.21538273 |
| 44 | MP0002160_abnormal_reproductive_system | 1.20326199 |
| 45 | MP0005360_urolithiasis | 1.19763845 |
| 46 | MP0003122_maternal_imprinting | 1.18684012 |
| 47 | MP0005389_reproductive_system_phenotype | 1.16889320 |
| 48 | MP0002638_abnormal_pupillary_reflex | 1.15131667 |
| 49 | MP0002102_abnormal_ear_morphology | 1.14298329 |
| 50 | MP0009745_abnormal_behavioral_response | 1.14042809 |
| 51 | MP0004145_abnormal_muscle_electrophysio | 1.10804168 |
| 52 | MP0005671_abnormal_response_to | 1.10780306 |
| 53 | MP0003806_abnormal_nucleotide_metabolis | 1.05367156 |
| 54 | MP0002733_abnormal_thermal_nociception | 1.04808687 |
| 55 | MP0005646_abnormal_pituitary_gland | 1.04716074 |
| 56 | MP0005083_abnormal_biliary_tract | 1.03670129 |
| 57 | MP0001970_abnormal_pain_threshold | 1.03099870 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.01819147 |
| 59 | MP0000631_abnormal_neuroendocrine_gland | 1.01344645 |
| 60 | MP0000778_abnormal_nervous_system | 0.99570904 |
| 61 | MP0002557_abnormal_social/conspecific_i | 0.97935067 |
| 62 | MP0001881_abnormal_mammary_gland | 0.95530449 |
| 63 | MP0000049_abnormal_middle_ear | 0.94811469 |
| 64 | MP0002751_abnormal_autonomic_nervous | 0.93064688 |
| 65 | MP0002148_abnormal_hypersensitivity_rea | 0.92769067 |
| 66 | MP0001529_abnormal_vocalization | 0.91342972 |
| 67 | MP0005636_abnormal_mineral_homeostasis | 0.91228239 |
| 68 | MP0001905_abnormal_dopamine_level | 0.90496795 |
| 69 | MP0004924_abnormal_behavior | 0.86658115 |
| 70 | MP0005386_behavior/neurological_phenoty | 0.86658115 |
| 71 | MP0002572_abnormal_emotion/affect_behav | 0.86004807 |
| 72 | MP0000538_abnormal_urinary_bladder | 0.85968487 |
| 73 | MP0005084_abnormal_gallbladder_morpholo | 0.85950888 |
| 74 | MP0003786_premature_aging | 0.81271716 |
| 75 | MP0001324_abnormal_eye_pigmentation | 0.80985991 |
| 76 | MP0001188_hyperpigmentation | 0.77614119 |
| 77 | MP0001919_abnormal_reproductive_system | 0.76965295 |
| 78 | MP0005253_abnormal_eye_physiology | 0.74840486 |
| 79 | MP0002064_seizures | 0.74812311 |
| 80 | MP0001879_abnormal_lymphatic_vessel | 0.74445360 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.72112110 |
| 82 | MP0002735_abnormal_chemical_nociception | 0.71804814 |
| 83 | MP0002734_abnormal_mechanical_nocicepti | 0.71532995 |
| 84 | MP0005410_abnormal_fertilization | 0.71242367 |
| 85 | MP0008775_abnormal_heart_ventricle | 0.70841258 |
| 86 | MP0005423_abnormal_somatic_nervous | 0.70311997 |
| 87 | MP0001664_abnormal_digestion | 0.68472642 |
| 88 | MP0008789_abnormal_olfactory_epithelium | 0.67694307 |
| 89 | MP0000026_abnormal_inner_ear | 0.67622973 |
| 90 | MP0002938_white_spotting | 0.66730212 |
| 91 | MP0002138_abnormal_hepatobiliary_system | 0.66413437 |
| 92 | MP0005332_abnormal_amino_acid | 0.65827966 |
| 93 | MP0000470_abnormal_stomach_morphology | 0.64524752 |
| 94 | MP0005195_abnormal_posterior_eye | 0.62549401 |
| 95 | MP0002229_neurodegeneration | 0.61726871 |
| 96 | MP0001485_abnormal_pinna_reflex | 0.61323700 |
| 97 | MP0000516_abnormal_urinary_system | 0.60977011 |
| 98 | MP0005367_renal/urinary_system_phenotyp | 0.60977011 |
| 99 | MP0002184_abnormal_innervation | 0.60808249 |
| 100 | MP0000230_abnormal_systemic_arterial | 0.60806138 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormal hemoglobin (HP:0011902) | 6.90945057 |
| 2 | Reticulocytopenia (HP:0001896) | 5.69317184 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.03640946 |
| 4 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 4.44547424 |
| 5 | Pallor (HP:0000980) | 4.23029809 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 4.17991431 |
| 7 | Keratoconus (HP:0000563) | 4.08643179 |
| 8 | Increased corneal curvature (HP:0100692) | 4.08643179 |
| 9 | Macrocytic anemia (HP:0001972) | 3.97245750 |
| 10 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.88457153 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.83919384 |
| 12 | Stenosis of the external auditory canal (HP:0000402) | 3.80963485 |
| 13 | Pancreatic cysts (HP:0001737) | 3.72035663 |
| 14 | Acute encephalopathy (HP:0006846) | 3.65150975 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.64625218 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.64625218 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.58677216 |
| 18 | Abnormal number of erythroid precursors (HP:0012131) | 3.55347441 |
| 19 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.52475031 |
| 20 | True hermaphroditism (HP:0010459) | 3.10435328 |
| 21 | Nephronophthisis (HP:0000090) | 3.05019240 |
| 22 | Pendular nystagmus (HP:0012043) | 3.02198487 |
| 23 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.00794356 |
| 24 | Cystic liver disease (HP:0006706) | 2.96773770 |
| 25 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.96519096 |
| 26 | Decreased central vision (HP:0007663) | 2.90732062 |
| 27 | Optic disc pallor (HP:0000543) | 2.88700114 |
| 28 | Abnormality of the renal medulla (HP:0100957) | 2.87324776 |
| 29 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.82626723 |
| 30 | Type II lissencephaly (HP:0007260) | 2.80539102 |
| 31 | Mitochondrial inheritance (HP:0001427) | 2.78366992 |
| 32 | Anencephaly (HP:0002323) | 2.74670428 |
| 33 | Absent/shortened dynein arms (HP:0200106) | 2.73277078 |
| 34 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.73277078 |
| 35 | Focal motor seizures (HP:0011153) | 2.71309659 |
| 36 | Abnormality of the renal cortex (HP:0011035) | 2.69417335 |
| 37 | Confusion (HP:0001289) | 2.58676735 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.50200641 |
| 39 | Congenital stationary night blindness (HP:0007642) | 2.48479785 |
| 40 | Cerebral edema (HP:0002181) | 2.46823493 |
| 41 | Increased CSF lactate (HP:0002490) | 2.42969457 |
| 42 | Abnormality of homocysteine metabolism (HP:0010919) | 2.33887680 |
| 43 | Homocystinuria (HP:0002156) | 2.33887680 |
| 44 | Osteomalacia (HP:0002749) | 2.31900791 |
| 45 | Abnormality of reticulocytes (HP:0004312) | 2.31337812 |
| 46 | 3-Methylglutaconic aciduria (HP:0003535) | 2.27788687 |
| 47 | Abnormal biliary tract physiology (HP:0012439) | 2.26803269 |
| 48 | Bile duct proliferation (HP:0001408) | 2.26803269 |
| 49 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.26320882 |
| 50 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.25480776 |
| 51 | Clumsiness (HP:0002312) | 2.24872137 |
| 52 | Septo-optic dysplasia (HP:0100842) | 2.14601036 |
| 53 | Asplenia (HP:0001746) | 2.12844792 |
| 54 | Gastrointestinal infarctions (HP:0005244) | 2.11543114 |
| 55 | Abnormality of the labia minora (HP:0012880) | 2.07709746 |
| 56 | Leukodystrophy (HP:0002415) | 2.05946463 |
| 57 | Sclerocornea (HP:0000647) | 2.05874166 |
| 58 | Supernumerary spleens (HP:0009799) | 2.05404392 |
| 59 | Congenital hepatic fibrosis (HP:0002612) | 2.00721211 |
| 60 | Medial flaring of the eyebrow (HP:0010747) | 1.99794925 |
| 61 | Constricted visual fields (HP:0001133) | 1.98659666 |
| 62 | Hypoplasia of the uterus (HP:0000013) | 1.95156125 |
| 63 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.93739916 |
| 64 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.93739916 |
| 65 | Colon cancer (HP:0003003) | 1.93261692 |
| 66 | Absent thumb (HP:0009777) | 1.91940328 |
| 67 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.88989262 |
| 68 | Thyroid-stimulating hormone excess (HP:0002925) | 1.86252336 |
| 69 | Depressed nasal ridge (HP:0000457) | 1.86251934 |
| 70 | Abnormality of cochlea (HP:0000375) | 1.86154946 |
| 71 | Abnormality of serum amino acid levels (HP:0003112) | 1.86082673 |
| 72 | Chorioretinal atrophy (HP:0000533) | 1.85636297 |
| 73 | Inability to walk (HP:0002540) | 1.84630612 |
| 74 | Hyperglycinemia (HP:0002154) | 1.84131869 |
| 75 | Adrenal hypoplasia (HP:0000835) | 1.83890980 |
| 76 | Chronic hepatic failure (HP:0100626) | 1.83765092 |
| 77 | Male pseudohermaphroditism (HP:0000037) | 1.83386245 |
| 78 | Optic nerve hypoplasia (HP:0000609) | 1.83271383 |
| 79 | Brushfield spots (HP:0001088) | 1.82705247 |
| 80 | Increased serum lactate (HP:0002151) | 1.81554298 |
| 81 | Enlarged kidneys (HP:0000105) | 1.79356914 |
| 82 | Stomatitis (HP:0010280) | 1.78792432 |
| 83 | Abnormality of renal resorption (HP:0011038) | 1.78184604 |
| 84 | Type 2 muscle fiber atrophy (HP:0003554) | 1.77934288 |
| 85 | Hyperglycinuria (HP:0003108) | 1.77025890 |
| 86 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.74222477 |
| 87 | Abnormal drinking behavior (HP:0030082) | 1.73198264 |
| 88 | Polydipsia (HP:0001959) | 1.73198264 |
| 89 | Chronic bronchitis (HP:0004469) | 1.67694405 |
| 90 | Abnormality of macular pigmentation (HP:0008002) | 1.66857556 |
| 91 | Tubular atrophy (HP:0000092) | 1.66635748 |
| 92 | Tubulointerstitial fibrosis (HP:0005576) | 1.66333652 |
| 93 | Congenital, generalized hypertrichosis (HP:0004540) | 1.66066602 |
| 94 | Thrombocytosis (HP:0001894) | 1.64904799 |
| 95 | Attenuation of retinal blood vessels (HP:0007843) | 1.64786871 |
| 96 | Progressive inability to walk (HP:0002505) | 1.63697088 |
| 97 | Hyperthyroidism (HP:0000836) | 1.62389093 |
| 98 | Polyphagia (HP:0002591) | 1.62349167 |
| 99 | Abnormal ciliary motility (HP:0012262) | 1.61982865 |
| 100 | Potter facies (HP:0002009) | 1.60546459 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | FRK | 3.68752846 |
| 2 | ADRBK2 | 3.01982736 |
| 3 | MAP3K13 | 2.92556382 |
| 4 | EIF2AK1 | 2.85978792 |
| 5 | TAOK3 | 2.59569181 |
| 6 | GRK1 | 2.55503848 |
| 7 | WNK4 | 2.32033486 |
| 8 | MAP4K2 | 2.17470069 |
| 9 | PIK3CA | 2.09806160 |
| 10 | NUAK1 | 1.98087948 |
| 11 | VRK2 | 1.97632539 |
| 12 | PHKG2 | 1.83274899 |
| 13 | PHKG1 | 1.83274899 |
| 14 | EPHB2 | 1.74331722 |
| 15 | TEC | 1.68297153 |
| 16 | DYRK2 | 1.67024430 |
| 17 | AKT3 | 1.66377257 |
| 18 | IKBKB | 1.63974849 |
| 19 | CSNK1G3 | 1.63558485 |
| 20 | BMPR1B | 1.61664953 |
| 21 | PINK1 | 1.60815071 |
| 22 | CDK19 | 1.52624360 |
| 23 | CSNK1G2 | 1.44794067 |
| 24 | CSNK1G1 | 1.42763635 |
| 25 | TRPM7 | 1.40679511 |
| 26 | TIE1 | 1.32085427 |
| 27 | PDK2 | 1.27963512 |
| 28 | ZAK | 1.26924104 |
| 29 | CSNK1A1L | 1.25337260 |
| 30 | TLK1 | 1.24252343 |
| 31 | RPS6KB2 | 1.18837419 |
| 32 | ACVR1B | 1.14589165 |
| 33 | MAP3K12 | 1.10563456 |
| 34 | BCKDK | 1.09919302 |
| 35 | RPS6KA6 | 1.08535027 |
| 36 | ADRBK1 | 1.08310570 |
| 37 | MAP4K1 | 1.06090306 |
| 38 | TGFBR1 | 1.05040769 |
| 39 | KIT | 1.02154376 |
| 40 | OXSR1 | 0.99520370 |
| 41 | RPS6KC1 | 0.96686855 |
| 42 | RPS6KL1 | 0.96686855 |
| 43 | TXK | 0.96147163 |
| 44 | ITK | 0.91565946 |
| 45 | NME2 | 0.89228430 |
| 46 | NTRK3 | 0.86742184 |
| 47 | TYRO3 | 0.86418727 |
| 48 | PRKCQ | 0.83635526 |
| 49 | MAPK13 | 0.83425431 |
| 50 | CHEK2 | 0.82476799 |
| 51 | DAPK3 | 0.82226246 |
| 52 | PLK2 | 0.82067317 |
| 53 | BTK | 0.81616677 |
| 54 | STK11 | 0.80956590 |
| 55 | PRKCG | 0.80619199 |
| 56 | VRK1 | 0.79974715 |
| 57 | MOS | 0.78485414 |
| 58 | RPS6KA5 | 0.76284229 |
| 59 | LRRK2 | 0.72570046 |
| 60 | PRKACA | 0.71882439 |
| 61 | INSRR | 0.71771040 |
| 62 | CAMK2A | 0.70895717 |
| 63 | CAMK2D | 0.70168422 |
| 64 | MAPKAPK5 | 0.69989998 |
| 65 | MKNK2 | 0.69208964 |
| 66 | GRK7 | 0.68309402 |
| 67 | BRAF | 0.66920192 |
| 68 | CHUK | 0.66267290 |
| 69 | MAP3K7 | 0.65967672 |
| 70 | PAK6 | 0.65517404 |
| 71 | CSNK2A2 | 0.65273195 |
| 72 | PIK3CG | 0.64914238 |
| 73 | EPHA4 | 0.62013934 |
| 74 | RPS6KB1 | 0.61290618 |
| 75 | PRKCE | 0.59995445 |
| 76 | JAK3 | 0.57895492 |
| 77 | PRKCI | 0.57775780 |
| 78 | MAP3K11 | 0.56615889 |
| 79 | PRKCA | 0.55401952 |
| 80 | CASK | 0.55002891 |
| 81 | PRKG1 | 0.54420529 |
| 82 | PAK3 | 0.54404407 |
| 83 | GRK5 | 0.53523192 |
| 84 | MAPKAPK3 | 0.53128758 |
| 85 | PLK3 | 0.52988734 |
| 86 | OBSCN | 0.52103332 |
| 87 | PRKCZ | 0.51167007 |
| 88 | PRKCH | 0.50922069 |
| 89 | PRKCD | 0.49791744 |
| 90 | MYLK | 0.47323960 |
| 91 | CAMKK2 | 0.46072422 |
| 92 | MARK1 | 0.44957523 |
| 93 | ABL2 | 0.44709379 |
| 94 | MUSK | 0.44213918 |
| 95 | STK16 | 0.43208213 |
| 96 | SGK1 | 0.42938181 |
| 97 | CSNK1A1 | 0.42294789 |
| 98 | PRKACG | 0.41204836 |
| 99 | DYRK1A | 0.39741616 |
| 100 | SGK223 | 0.39016615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.26474830 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.43064264 |
| 3 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.91485832 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.77894718 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.49162906 |
| 6 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.40178692 |
| 7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.38369626 |
| 8 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.15259033 |
| 9 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.97427328 |
| 10 | Phototransduction_Homo sapiens_hsa04744 | 1.91868659 |
| 11 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.90735865 |
| 12 | Alzheimers disease_Homo sapiens_hsa05010 | 1.89329714 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88316056 |
| 14 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.87247616 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.87036616 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.85724234 |
| 17 | Basal transcription factors_Homo sapiens_hsa03022 | 1.77739073 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.75974668 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.64139607 |
| 20 | Allograft rejection_Homo sapiens_hsa05330 | 1.63909802 |
| 21 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.58134069 |
| 22 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.55011835 |
| 23 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.53889431 |
| 24 | Nicotine addiction_Homo sapiens_hsa05033 | 1.53064251 |
| 25 | Proteasome_Homo sapiens_hsa03050 | 1.51156351 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.50889026 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.47974869 |
| 28 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.38827746 |
| 29 | Mineral absorption_Homo sapiens_hsa04978 | 1.37950063 |
| 30 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.35262823 |
| 31 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.32649106 |
| 32 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.31037134 |
| 33 | Olfactory transduction_Homo sapiens_hsa04740 | 1.30136896 |
| 34 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.28274256 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.21948158 |
| 36 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.21903895 |
| 37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.19012769 |
| 38 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.18529941 |
| 39 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.16598983 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.16209521 |
| 41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.16003830 |
| 42 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.13579180 |
| 43 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.12619005 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 1.10058182 |
| 45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.08358186 |
| 46 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.04596139 |
| 47 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.01065626 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.95898858 |
| 49 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.91100292 |
| 50 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.88874074 |
| 51 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.88164733 |
| 52 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85098266 |
| 53 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.84390546 |
| 54 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.79230106 |
| 55 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74473814 |
| 56 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.74227798 |
| 57 | Morphine addiction_Homo sapiens_hsa05032 | 0.72209283 |
| 58 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.69536764 |
| 59 | Homologous recombination_Homo sapiens_hsa03440 | 0.68628906 |
| 60 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.67718106 |
| 61 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.61142166 |
| 62 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.60763913 |
| 63 | Metabolic pathways_Homo sapiens_hsa01100 | 0.59912756 |
| 64 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.59653841 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.57505147 |
| 66 | Insulin secretion_Homo sapiens_hsa04911 | 0.53127345 |
| 67 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.53059595 |
| 68 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.52798722 |
| 69 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52528944 |
| 70 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.52355803 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51419010 |
| 72 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.49552272 |
| 73 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.49424003 |
| 74 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.48395857 |
| 75 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.47669723 |
| 76 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.47590402 |
| 77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.46599005 |
| 78 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.45689454 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.45522069 |
| 80 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.45105522 |
| 81 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.43618692 |
| 82 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.43254304 |
| 83 | Taste transduction_Homo sapiens_hsa04742 | 0.43026925 |
| 84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.42502634 |
| 85 | Salivary secretion_Homo sapiens_hsa04970 | 0.38776286 |
| 86 | Purine metabolism_Homo sapiens_hsa00230 | 0.38700008 |
| 87 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.37470303 |
| 88 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.36354347 |
| 89 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.35314320 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32619158 |
| 91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.30577064 |
| 92 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.30240928 |
| 93 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.29510566 |
| 94 | Bile secretion_Homo sapiens_hsa04976 | 0.28665776 |
| 95 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.26290328 |
| 96 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.24655301 |
| 97 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.22736102 |
| 98 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.21061357 |
| 99 | Histidine metabolism_Homo sapiens_hsa00340 | 0.20949974 |
| 100 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.20418488 |

