

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | protein neddylation (GO:0045116) | 6.55929552 |
| 2 | maturation of SSU-rRNA (GO:0030490) | 6.34399129 |
| 3 | chaperone-mediated protein transport (GO:0072321) | 5.98125025 |
| 4 | DNA deamination (GO:0045006) | 5.72920958 |
| 5 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.29492098 |
| 6 | proteasome assembly (GO:0043248) | 4.89457325 |
| 7 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.57852911 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.35122403 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.35122403 |
| 10 | negative regulation by host of viral transcription (GO:0043922) | 4.19867592 |
| 11 | behavioral response to nicotine (GO:0035095) | 4.15521224 |
| 12 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.05308228 |
| 13 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.03633906 |
| 14 | NADH dehydrogenase complex assembly (GO:0010257) | 4.03633906 |
| 15 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.03633906 |
| 16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.02451223 |
| 17 | peptidyl-histidine modification (GO:0018202) | 3.91431850 |
| 18 | positive regulation of protein homooligomerization (GO:0032464) | 3.89642462 |
| 19 | protein targeting to mitochondrion (GO:0006626) | 3.89091288 |
| 20 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.89068773 |
| 21 | cytidine deamination (GO:0009972) | 3.83779861 |
| 22 | cytidine metabolic process (GO:0046087) | 3.83779861 |
| 23 | cytidine catabolic process (GO:0006216) | 3.83779861 |
| 24 | ribosomal small subunit biogenesis (GO:0042274) | 3.76256021 |
| 25 | neuromuscular process controlling posture (GO:0050884) | 3.75742538 |
| 26 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.72526910 |
| 27 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.72526910 |
| 28 | protein complex biogenesis (GO:0070271) | 3.65712597 |
| 29 | establishment of protein localization to mitochondrion (GO:0072655) | 3.64821003 |
| 30 | protein-cofactor linkage (GO:0018065) | 3.62858142 |
| 31 | viral transcription (GO:0019083) | 3.62608755 |
| 32 | translational termination (GO:0006415) | 3.57806668 |
| 33 | maturation of 5.8S rRNA (GO:0000460) | 3.57635977 |
| 34 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 3.57430254 |
| 35 | ribosomal large subunit biogenesis (GO:0042273) | 3.52725898 |
| 36 | protein localization to mitochondrion (GO:0070585) | 3.50435706 |
| 37 | pseudouridine synthesis (GO:0001522) | 3.49229106 |
| 38 | ear development (GO:0043583) | 3.48629426 |
| 39 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.44371585 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.38476573 |
| 41 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.32735124 |
| 42 | protein localization to cilium (GO:0061512) | 3.31554942 |
| 43 | cotranslational protein targeting to membrane (GO:0006613) | 3.30097170 |
| 44 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.29833928 |
| 45 | protein targeting to ER (GO:0045047) | 3.28792562 |
| 46 | histone mRNA metabolic process (GO:0008334) | 3.26164371 |
| 47 | negative regulation of telomere maintenance (GO:0032205) | 3.24716483 |
| 48 | termination of RNA polymerase III transcription (GO:0006386) | 3.21377365 |
| 49 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.21377365 |
| 50 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.21088441 |
| 51 | translational elongation (GO:0006414) | 3.20705369 |
| 52 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.19394497 |
| 53 | cellular component biogenesis (GO:0044085) | 3.18892422 |
| 54 | muscle organ morphogenesis (GO:0048644) | 3.15544886 |
| 55 | histone H2A acetylation (GO:0043968) | 3.15322758 |
| 56 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.15060089 |
| 57 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.11375995 |
| 58 | protein localization to endoplasmic reticulum (GO:0070972) | 3.09487141 |
| 59 | electron transport chain (GO:0022900) | 3.08950544 |
| 60 | positive regulation of T cell apoptotic process (GO:0070234) | 3.07682116 |
| 61 | translation (GO:0006412) | 3.07618647 |
| 62 | 7-methylguanosine mRNA capping (GO:0006370) | 3.05936719 |
| 63 | respiratory electron transport chain (GO:0022904) | 3.04560841 |
| 64 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.03177968 |
| 65 | preassembly of GPI anchor in ER membrane (GO:0016254) | 3.00818658 |
| 66 | spliceosomal snRNP assembly (GO:0000387) | 3.00005713 |
| 67 | RNA capping (GO:0036260) | 2.98413626 |
| 68 | 7-methylguanosine RNA capping (GO:0009452) | 2.98413626 |
| 69 | melanosome localization (GO:0032400) | 2.90863519 |
| 70 | rRNA catabolic process (GO:0016075) | 2.90795418 |
| 71 | positive regulation of macrophage differentiation (GO:0045651) | 2.87698294 |
| 72 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 2.85663899 |
| 73 | ribosome assembly (GO:0042255) | 2.83876858 |
| 74 | GPI anchor metabolic process (GO:0006505) | 2.83615015 |
| 75 | organelle disassembly (GO:1903008) | 2.82625909 |
| 76 | translational initiation (GO:0006413) | 2.82336371 |
| 77 | ribonucleoprotein complex disassembly (GO:0032988) | 2.81306368 |
| 78 | polarized epithelial cell differentiation (GO:0030859) | 2.80334358 |
| 79 | protein K11-linked ubiquitination (GO:0070979) | 2.80060598 |
| 80 | cullin deneddylation (GO:0010388) | 2.79874826 |
| 81 | intracellular protein transmembrane import (GO:0044743) | 2.79150347 |
| 82 | ribosome biogenesis (GO:0042254) | 2.78953850 |
| 83 | isotype switching (GO:0045190) | 2.78190015 |
| 84 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.78190015 |
| 85 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.78190015 |
| 86 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.78064575 |
| 87 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.77967738 |
| 88 | pigment granule localization (GO:0051875) | 2.77024220 |
| 89 | rRNA processing (GO:0006364) | 2.73789304 |
| 90 | rRNA metabolic process (GO:0016072) | 2.72994140 |
| 91 | positive regulation of protein oligomerization (GO:0032461) | 2.71360813 |
| 92 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.71312832 |
| 93 | cellular protein complex disassembly (GO:0043624) | 2.70823409 |
| 94 | interferon-gamma production (GO:0032609) | 2.69933705 |
| 95 | regulation of catecholamine metabolic process (GO:0042069) | 2.69157652 |
| 96 | regulation of dopamine metabolic process (GO:0042053) | 2.69157652 |
| 97 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.68588711 |
| 98 | kinetochore assembly (GO:0051382) | 2.68145957 |
| 99 | tRNA processing (GO:0008033) | 2.65743752 |
| 100 | base-excision repair, AP site formation (GO:0006285) | 2.65400505 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.20085998 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.35669909 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.84048703 |
| 4 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.51545975 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.42790181 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.36883601 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.05742125 |
| 8 | VDR_22108803_ChIP-Seq_LS180_Human | 2.83768994 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.82249485 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.80239084 |
| 11 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.66904417 |
| 12 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.49241034 |
| 13 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.45166970 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.44046089 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.39690841 |
| 16 | IRF1_19129219_ChIP-ChIP_H3396_Human | 2.39451732 |
| 17 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.30901836 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.30804822 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.23639144 |
| 20 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.10139328 |
| 21 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.05285345 |
| 22 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.02542821 |
| 23 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.94810933 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.91097854 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.90165034 |
| 26 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.88868848 |
| 27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.88501061 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.85723475 |
| 29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.85514074 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.83562089 |
| 31 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.83247278 |
| 32 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.83089060 |
| 33 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.77937328 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.77078629 |
| 35 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.65360324 |
| 36 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.59275991 |
| 37 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.58565349 |
| 38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.55421940 |
| 39 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.50524943 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.45546100 |
| 41 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.44692541 |
| 42 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.42108326 |
| 43 | FUS_26573619_Chip-Seq_HEK293_Human | 1.37783395 |
| 44 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.35935233 |
| 45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.35199517 |
| 46 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.34959468 |
| 47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32447839 |
| 48 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.31758410 |
| 49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.23959736 |
| 50 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.21608104 |
| 51 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21102818 |
| 52 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.16555561 |
| 53 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.16391271 |
| 54 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.14825902 |
| 55 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.14678034 |
| 56 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13831426 |
| 57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.11983379 |
| 58 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.09159225 |
| 59 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.08163330 |
| 60 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.07790221 |
| 61 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.07544875 |
| 62 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06887371 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.05840106 |
| 64 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.05290731 |
| 65 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.05071093 |
| 66 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.04643121 |
| 67 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03285398 |
| 68 | AR_20517297_ChIP-Seq_VCAP_Human | 1.00174175 |
| 69 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.99751035 |
| 70 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98690684 |
| 71 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97376195 |
| 72 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 0.97201965 |
| 73 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.96602815 |
| 74 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95031806 |
| 75 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.94873874 |
| 76 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.93624608 |
| 77 | NCOR_22424771_ChIP-Seq_293T_Human | 0.92883880 |
| 78 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.92644132 |
| 79 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.91670240 |
| 80 | GATA3_26560356_Chip-Seq_TH2_Human | 0.90698471 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.90513863 |
| 82 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.89773547 |
| 83 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.87457124 |
| 84 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.86570819 |
| 85 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.86446062 |
| 86 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 0.85982012 |
| 87 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.85587591 |
| 88 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.85391059 |
| 89 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.83025710 |
| 90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.82928326 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.82695040 |
| 92 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.82378420 |
| 93 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.81222415 |
| 94 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.81142373 |
| 95 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.80089524 |
| 96 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.79438646 |
| 97 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.77883323 |
| 98 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76888108 |
| 99 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.75832635 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.75241921 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001984_abnormal_olfaction | 3.20101393 |
| 2 | MP0005075_abnormal_melanosome_morpholog | 2.92476433 |
| 3 | MP0000372_irregular_coat_pigmentation | 2.90990847 |
| 4 | MP0003941_abnormal_skin_development | 2.70869462 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.66285312 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.66120107 |
| 7 | MP0003195_calcinosis | 2.40153946 |
| 8 | MP0002938_white_spotting | 2.39520002 |
| 9 | MP0008995_early_reproductive_senescence | 2.37437289 |
| 10 | MP0009379_abnormal_foot_pigmentation | 2.35718302 |
| 11 | MP0003122_maternal_imprinting | 2.23132487 |
| 12 | MP0004742_abnormal_vestibular_system | 2.17369277 |
| 13 | MP0004145_abnormal_muscle_electrophysio | 2.16006387 |
| 14 | MP0005646_abnormal_pituitary_gland | 2.00993972 |
| 15 | MP0005387_immune_system_phenotype | 1.99192586 |
| 16 | MP0001790_abnormal_immune_system | 1.99192586 |
| 17 | MP0002138_abnormal_hepatobiliary_system | 1.91018028 |
| 18 | MP0005408_hypopigmentation | 1.77966082 |
| 19 | MP0002163_abnormal_gland_morphology | 1.75556392 |
| 20 | MP0003121_genomic_imprinting | 1.75095083 |
| 21 | MP0003806_abnormal_nucleotide_metabolis | 1.75062520 |
| 22 | MP0002653_abnormal_ependyma_morphology | 1.73226099 |
| 23 | MP0005671_abnormal_response_to | 1.72773049 |
| 24 | MP0001485_abnormal_pinna_reflex | 1.67898326 |
| 25 | MP0003646_muscle_fatigue | 1.66863061 |
| 26 | MP0002277_abnormal_respiratory_mucosa | 1.63938903 |
| 27 | MP0002234_abnormal_pharynx_morphology | 1.62333387 |
| 28 | MP0009046_muscle_twitch | 1.61503494 |
| 29 | MP0008789_abnormal_olfactory_epithelium | 1.60944053 |
| 30 | MP0005084_abnormal_gallbladder_morpholo | 1.60521660 |
| 31 | MP0002148_abnormal_hypersensitivity_rea | 1.52869541 |
| 32 | MP0001501_abnormal_sleep_pattern | 1.52678102 |
| 33 | MP0005174_abnormal_tail_pigmentation | 1.46588354 |
| 34 | MP0001188_hyperpigmentation | 1.41560179 |
| 35 | MP0005253_abnormal_eye_physiology | 1.40699056 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.37464082 |
| 37 | MP0000049_abnormal_middle_ear | 1.37205993 |
| 38 | MP0009764_decreased_sensitivity_to | 1.35397704 |
| 39 | MP0004142_abnormal_muscle_tone | 1.33752778 |
| 40 | MP0003786_premature_aging | 1.33059858 |
| 41 | MP0009697_abnormal_copulation | 1.32811727 |
| 42 | MP0006276_abnormal_autonomic_nervous | 1.31697702 |
| 43 | MP0008058_abnormal_DNA_repair | 1.27283176 |
| 44 | MP0005389_reproductive_system_phenotype | 1.24348670 |
| 45 | MP0001873_stomach_inflammation | 1.20862062 |
| 46 | MP0001835_abnormal_antigen_presentation | 1.20680998 |
| 47 | MP0002160_abnormal_reproductive_system | 1.20057557 |
| 48 | MP0000685_abnormal_immune_system | 1.18955016 |
| 49 | MP0003186_abnormal_redox_activity | 1.16403135 |
| 50 | MP0005394_taste/olfaction_phenotype | 1.14430050 |
| 51 | MP0005499_abnormal_olfactory_system | 1.14430050 |
| 52 | MP0002102_abnormal_ear_morphology | 1.13092576 |
| 53 | MP0009765_abnormal_xenobiotic_induced | 1.12029317 |
| 54 | MP0008007_abnormal_cellular_replicative | 1.11991943 |
| 55 | MP0005423_abnormal_somatic_nervous | 1.11152982 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 1.09225082 |
| 57 | MP0003718_maternal_effect | 1.08968160 |
| 58 | MP0003693_abnormal_embryo_hatching | 1.08866156 |
| 59 | MP0001293_anophthalmia | 1.08606485 |
| 60 | MP0001905_abnormal_dopamine_level | 1.06370901 |
| 61 | MP0001919_abnormal_reproductive_system | 1.05870673 |
| 62 | MP0002735_abnormal_chemical_nociception | 1.04152011 |
| 63 | MP0000569_abnormal_digit_pigmentation | 1.02936932 |
| 64 | MP0003787_abnormal_imprinting | 1.02693138 |
| 65 | MP0005551_abnormal_eye_electrophysiolog | 1.01602211 |
| 66 | MP0004147_increased_porphyrin_level | 0.99524048 |
| 67 | MP0008875_abnormal_xenobiotic_pharmacok | 0.95358525 |
| 68 | MP0000371_diluted_coat_color | 0.95090054 |
| 69 | MP0008872_abnormal_physiological_respon | 0.95005134 |
| 70 | MP0009745_abnormal_behavioral_response | 0.94351200 |
| 71 | MP0002095_abnormal_skin_pigmentation | 0.93695136 |
| 72 | MP0005195_abnormal_posterior_eye | 0.90254246 |
| 73 | MP0000604_amyloidosis | 0.89816391 |
| 74 | MP0004957_abnormal_blastocyst_morpholog | 0.89120592 |
| 75 | MP0001800_abnormal_humoral_immune | 0.87387955 |
| 76 | MP0001963_abnormal_hearing_physiology | 0.86681232 |
| 77 | MP0005167_abnormal_blood-brain_barrier | 0.83854164 |
| 78 | MP0002132_abnormal_respiratory_system | 0.82530121 |
| 79 | MP0004043_abnormal_pH_regulation | 0.81324862 |
| 80 | MP0001502_abnormal_circadian_rhythm | 0.78812469 |
| 81 | MP0010386_abnormal_urinary_bladder | 0.78180177 |
| 82 | MP0006035_abnormal_mitochondrial_morpho | 0.78088238 |
| 83 | MP0003763_abnormal_thymus_physiology | 0.77841539 |
| 84 | MP0002177_abnormal_outer_ear | 0.77474981 |
| 85 | MP0004885_abnormal_endolymph | 0.77432498 |
| 86 | MP0001270_distended_abdomen | 0.77284951 |
| 87 | MP0001881_abnormal_mammary_gland | 0.76800321 |
| 88 | MP0002557_abnormal_social/conspecific_i | 0.76270879 |
| 89 | MP0003329_amyloid_beta_deposits | 0.74762355 |
| 90 | MP0002067_abnormal_sensory_capabilities | 0.73023807 |
| 91 | MP0008873_increased_physiological_sensi | 0.71731131 |
| 92 | MP0005410_abnormal_fertilization | 0.71684083 |
| 93 | MP0005379_endocrine/exocrine_gland_phen | 0.71398347 |
| 94 | MP0005464_abnormal_platelet_physiology | 0.71144614 |
| 95 | MP0003137_abnormal_impulse_conducting | 0.70972223 |
| 96 | MP0002572_abnormal_emotion/affect_behav | 0.69680774 |
| 97 | MP0008877_abnormal_DNA_methylation | 0.69468962 |
| 98 | MP0002638_abnormal_pupillary_reflex | 0.69117206 |
| 99 | MP0001764_abnormal_homeostasis | 0.68966234 |
| 100 | MP0002272_abnormal_nervous_system | 0.67119402 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.57328158 |
| 2 | Acute encephalopathy (HP:0006846) | 4.31698296 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.07152324 |
| 4 | Abnormality of alanine metabolism (HP:0010916) | 3.87350696 |
| 5 | Hyperalaninemia (HP:0003348) | 3.87350696 |
| 6 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.87350696 |
| 7 | Mitochondrial inheritance (HP:0001427) | 3.87297038 |
| 8 | Increased CSF lactate (HP:0002490) | 3.77961288 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.58745701 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.51461400 |
| 11 | Nephronophthisis (HP:0000090) | 3.30776629 |
| 12 | Abnormality of midbrain morphology (HP:0002418) | 3.25615849 |
| 13 | Molar tooth sign on MRI (HP:0002419) | 3.25615849 |
| 14 | Colon cancer (HP:0003003) | 3.19945103 |
| 15 | Increased serum lactate (HP:0002151) | 3.14160124 |
| 16 | Medial flaring of the eyebrow (HP:0010747) | 3.12508776 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.11288946 |
| 18 | Attenuation of retinal blood vessels (HP:0007843) | 3.03092552 |
| 19 | Degeneration of anterior horn cells (HP:0002398) | 2.93333850 |
| 20 | Abnormality of the anterior horn cell (HP:0006802) | 2.93333850 |
| 21 | Hyperglycinemia (HP:0002154) | 2.93179878 |
| 22 | Optic disc pallor (HP:0000543) | 2.92812583 |
| 23 | Pancreatic fibrosis (HP:0100732) | 2.90684663 |
| 24 | Pancreatic cysts (HP:0001737) | 2.90066036 |
| 25 | Abnormal pupillary function (HP:0007686) | 2.85776331 |
| 26 | Nephrogenic diabetes insipidus (HP:0009806) | 2.83032555 |
| 27 | Lactic acidosis (HP:0003128) | 2.81308805 |
| 28 | Abnormality of the renal cortex (HP:0011035) | 2.78184642 |
| 29 | Reticulocytopenia (HP:0001896) | 2.75496891 |
| 30 | Stomatitis (HP:0010280) | 2.72311345 |
| 31 | Abnormality of the renal medulla (HP:0100957) | 2.72113443 |
| 32 | 3-Methylglutaconic aciduria (HP:0003535) | 2.71480588 |
| 33 | Pendular nystagmus (HP:0012043) | 2.69934051 |
| 34 | Abolished electroretinogram (ERG) (HP:0000550) | 2.69246022 |
| 35 | Cerebral edema (HP:0002181) | 2.65459628 |
| 36 | Increased intramyocellular lipid droplets (HP:0012240) | 2.63843592 |
| 37 | Focal motor seizures (HP:0011153) | 2.55716443 |
| 38 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.53916121 |
| 39 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.53916121 |
| 40 | Congenital, generalized hypertrichosis (HP:0004540) | 2.53566044 |
| 41 | IgG deficiency (HP:0004315) | 2.51427326 |
| 42 | Gastrointestinal infarctions (HP:0005244) | 2.47125395 |
| 43 | Congenital primary aphakia (HP:0007707) | 2.44430137 |
| 44 | Gait imbalance (HP:0002141) | 2.41286938 |
| 45 | Adrenal hypoplasia (HP:0000835) | 2.40868388 |
| 46 | Hepatocellular necrosis (HP:0001404) | 2.38410806 |
| 47 | Hyperglycinuria (HP:0003108) | 2.32340404 |
| 48 | Parakeratosis (HP:0001036) | 2.27687019 |
| 49 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.26883828 |
| 50 | Tachypnea (HP:0002789) | 2.25699473 |
| 51 | Respiratory failure (HP:0002878) | 2.25438069 |
| 52 | Microretrognathia (HP:0000308) | 2.23222162 |
| 53 | Abnormality of serum amino acid levels (HP:0003112) | 2.18853853 |
| 54 | Macrocytic anemia (HP:0001972) | 2.16574845 |
| 55 | Tubular atrophy (HP:0000092) | 2.14253632 |
| 56 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.14209966 |
| 57 | Absent thumb (HP:0009777) | 2.13726953 |
| 58 | Abnormal number of incisors (HP:0011064) | 2.13422911 |
| 59 | Methylmalonic aciduria (HP:0012120) | 2.13157638 |
| 60 | Exertional dyspnea (HP:0002875) | 2.12665023 |
| 61 | Decreased central vision (HP:0007663) | 2.11724824 |
| 62 | Methylmalonic acidemia (HP:0002912) | 2.11533162 |
| 63 | Abnormality of glycine metabolism (HP:0010895) | 2.10963769 |
| 64 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.10963769 |
| 65 | True hermaphroditism (HP:0010459) | 2.07600278 |
| 66 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.07522152 |
| 67 | Stenosis of the external auditory canal (HP:0000402) | 2.04743762 |
| 68 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.00304630 |
| 69 | Increased muscle lipid content (HP:0009058) | 2.00247217 |
| 70 | Panhypogammaglobulinemia (HP:0003139) | 1.99166684 |
| 71 | Abnormality of the labia minora (HP:0012880) | 1.95574063 |
| 72 | Broad-based gait (HP:0002136) | 1.93453942 |
| 73 | Cystic liver disease (HP:0006706) | 1.92988654 |
| 74 | Lethargy (HP:0001254) | 1.91060211 |
| 75 | Renal Fanconi syndrome (HP:0001994) | 1.90657031 |
| 76 | Hepatic necrosis (HP:0002605) | 1.90399522 |
| 77 | Agitation (HP:0000713) | 1.89420634 |
| 78 | Renal cortical cysts (HP:0000803) | 1.88410671 |
| 79 | Submucous cleft hard palate (HP:0000176) | 1.88322072 |
| 80 | Exercise intolerance (HP:0003546) | 1.87941090 |
| 81 | Polydipsia (HP:0001959) | 1.87705149 |
| 82 | Abnormal drinking behavior (HP:0030082) | 1.87705149 |
| 83 | Blindness (HP:0000618) | 1.86400136 |
| 84 | Abnormality of T cell physiology (HP:0011840) | 1.85115750 |
| 85 | Congenital stationary night blindness (HP:0007642) | 1.84594292 |
| 86 | Hypoplastic pelvis (HP:0008839) | 1.83875893 |
| 87 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.83739760 |
| 88 | Type II lissencephaly (HP:0007260) | 1.83077718 |
| 89 | Spinal muscular atrophy (HP:0007269) | 1.82593881 |
| 90 | Increased IgM level (HP:0003496) | 1.82564785 |
| 91 | Progressive microcephaly (HP:0000253) | 1.82374699 |
| 92 | CNS demyelination (HP:0007305) | 1.80540905 |
| 93 | Congenital hepatic fibrosis (HP:0002612) | 1.78439326 |
| 94 | Visual hallucinations (HP:0002367) | 1.77167773 |
| 95 | Lissencephaly (HP:0001339) | 1.73713752 |
| 96 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.73588201 |
| 97 | Hemiplegia (HP:0002301) | 1.73239702 |
| 98 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.72904792 |
| 99 | Chronic hepatic failure (HP:0100626) | 1.71809618 |
| 100 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 1.70817455 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TAOK3 | 6.78650094 |
| 2 | MAP4K2 | 3.86751594 |
| 3 | BUB1 | 3.27434171 |
| 4 | TSSK6 | 3.01416413 |
| 5 | EIF2AK1 | 2.63821605 |
| 6 | SRPK1 | 2.62246213 |
| 7 | TXK | 2.32870179 |
| 8 | PASK | 2.27696896 |
| 9 | ADRBK2 | 2.22872004 |
| 10 | NEK1 | 2.03396655 |
| 11 | BMPR1B | 1.87632761 |
| 12 | TNK2 | 1.87120265 |
| 13 | CDK19 | 1.85789253 |
| 14 | ZAK | 1.68521352 |
| 15 | CSNK1G3 | 1.67769496 |
| 16 | NUAK1 | 1.54802480 |
| 17 | EIF2AK3 | 1.50642767 |
| 18 | PIK3CA | 1.44641357 |
| 19 | STK24 | 1.42335273 |
| 20 | CDK8 | 1.41430038 |
| 21 | KDR | 1.40266994 |
| 22 | ITK | 1.38547862 |
| 23 | CSNK1G1 | 1.37365768 |
| 24 | CSNK1A1L | 1.32641451 |
| 25 | CSNK1G2 | 1.31755221 |
| 26 | MAP4K1 | 1.30726130 |
| 27 | TAF1 | 1.29910602 |
| 28 | GRK1 | 1.28340107 |
| 29 | OXSR1 | 1.26405261 |
| 30 | DYRK2 | 1.23368302 |
| 31 | PDK2 | 1.20962108 |
| 32 | TLK1 | 1.17981062 |
| 33 | MAP2K7 | 1.16768226 |
| 34 | WNK4 | 1.11201007 |
| 35 | FGFR1 | 0.99803803 |
| 36 | IKBKB | 0.99771463 |
| 37 | VRK2 | 0.98388265 |
| 38 | STK38L | 0.95891109 |
| 39 | TBK1 | 0.93887424 |
| 40 | FES | 0.92762706 |
| 41 | VRK1 | 0.84223779 |
| 42 | PRKD3 | 0.82939886 |
| 43 | CCNB1 | 0.82267510 |
| 44 | PAK3 | 0.82192506 |
| 45 | STK39 | 0.81657882 |
| 46 | TIE1 | 0.81218824 |
| 47 | SIK3 | 0.81062495 |
| 48 | AURKA | 0.79945078 |
| 49 | PRKCQ | 0.79577953 |
| 50 | PRKCH | 0.78754849 |
| 51 | BCKDK | 0.78463961 |
| 52 | ALK | 0.77194060 |
| 53 | ADRBK1 | 0.72713130 |
| 54 | PINK1 | 0.69878873 |
| 55 | TGFBR1 | 0.69399354 |
| 56 | MAP3K12 | 0.69179812 |
| 57 | MAP3K11 | 0.67299699 |
| 58 | TESK2 | 0.65574257 |
| 59 | INSRR | 0.63748965 |
| 60 | BCR | 0.63689522 |
| 61 | PLK3 | 0.62489230 |
| 62 | ATR | 0.59587955 |
| 63 | LRRK2 | 0.56661678 |
| 64 | CSNK1A1 | 0.56559731 |
| 65 | ERBB3 | 0.56203819 |
| 66 | AKT3 | 0.55793531 |
| 67 | SIK2 | 0.55313097 |
| 68 | MKNK1 | 0.54094533 |
| 69 | KIT | 0.53996783 |
| 70 | CDC7 | 0.53732790 |
| 71 | TEC | 0.53727408 |
| 72 | CAMKK1 | 0.53029780 |
| 73 | IRAK3 | 0.51521356 |
| 74 | EIF2AK2 | 0.49993500 |
| 75 | IKBKE | 0.49844867 |
| 76 | PHKG2 | 0.48577390 |
| 77 | PHKG1 | 0.48577390 |
| 78 | LIMK1 | 0.48271785 |
| 79 | CSNK2A1 | 0.47680197 |
| 80 | SYK | 0.46893516 |
| 81 | WNK3 | 0.44919230 |
| 82 | CSNK2A2 | 0.44650235 |
| 83 | NME1 | 0.43443912 |
| 84 | LCK | 0.43048553 |
| 85 | OBSCN | 0.42547485 |
| 86 | RPS6KA5 | 0.42364098 |
| 87 | PRKCA | 0.40912306 |
| 88 | PTK2B | 0.40844265 |
| 89 | PLK4 | 0.38947698 |
| 90 | PRKACA | 0.38840843 |
| 91 | AURKB | 0.37546740 |
| 92 | CAMK2A | 0.36080994 |
| 93 | CHUK | 0.35991550 |
| 94 | PRKCE | 0.35189222 |
| 95 | PRKCZ | 0.34993491 |
| 96 | DAPK1 | 0.34533528 |
| 97 | PRKCG | 0.34226709 |
| 98 | PLK2 | 0.33214950 |
| 99 | STK10 | 0.32568747 |
| 100 | PLK1 | 0.29714854 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.72384626 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.34010222 |
| 3 | Basal transcription factors_Homo sapiens_hsa03022 | 3.10513566 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.07109549 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 2.91849894 |
| 6 | Protein export_Homo sapiens_hsa03060 | 2.76953043 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.74293701 |
| 8 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.34441357 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.25360537 |
| 10 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.18873576 |
| 11 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 2.18871216 |
| 12 | Huntingtons disease_Homo sapiens_hsa05016 | 2.15452332 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.09027742 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.92153030 |
| 15 | RNA degradation_Homo sapiens_hsa03018 | 1.90014818 |
| 16 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.79291557 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.73285917 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.73224549 |
| 19 | Sulfur relay system_Homo sapiens_hsa04122 | 1.67304716 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.64837121 |
| 21 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.63341117 |
| 22 | Spliceosome_Homo sapiens_hsa03040 | 1.63304610 |
| 23 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.49916702 |
| 24 | Allograft rejection_Homo sapiens_hsa05330 | 1.46892511 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.46830068 |
| 26 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.43938080 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.42999838 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38800656 |
| 29 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.38666023 |
| 30 | Asthma_Homo sapiens_hsa05310 | 1.29077931 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.28054812 |
| 32 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.25824428 |
| 33 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.25637383 |
| 34 | RNA transport_Homo sapiens_hsa03013 | 1.25434631 |
| 35 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.21414259 |
| 36 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.16012191 |
| 37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.13530611 |
| 38 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 1.08214505 |
| 39 | DNA replication_Homo sapiens_hsa03030 | 1.07428553 |
| 40 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.04932648 |
| 41 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.03204008 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.00930955 |
| 43 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.96546787 |
| 44 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.96052436 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 0.94246755 |
| 46 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.93859265 |
| 47 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.93327611 |
| 48 | Base excision repair_Homo sapiens_hsa03410 | 0.93200312 |
| 49 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.91489067 |
| 50 | Purine metabolism_Homo sapiens_hsa00230 | 0.88499026 |
| 51 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.86523748 |
| 52 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80751265 |
| 53 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.79661057 |
| 54 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.78775460 |
| 55 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.77396689 |
| 56 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.74071261 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.73749108 |
| 58 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.72577845 |
| 59 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.72575254 |
| 60 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72184017 |
| 61 | Homologous recombination_Homo sapiens_hsa03440 | 0.71852620 |
| 62 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.70704608 |
| 63 | Mismatch repair_Homo sapiens_hsa03430 | 0.68530163 |
| 64 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.68166605 |
| 65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.66890603 |
| 66 | Olfactory transduction_Homo sapiens_hsa04740 | 0.65032946 |
| 67 | Metabolic pathways_Homo sapiens_hsa01100 | 0.63604676 |
| 68 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.62288666 |
| 69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59484310 |
| 70 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.59317055 |
| 71 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58506966 |
| 72 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.58421148 |
| 73 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.58201282 |
| 74 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54858861 |
| 75 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.53672861 |
| 76 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.53590044 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.51376989 |
| 78 | Measles_Homo sapiens_hsa05162 | 0.50465887 |
| 79 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.47262364 |
| 80 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.47084078 |
| 81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.46749754 |
| 82 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.46052110 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44719626 |
| 84 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.43748312 |
| 85 | Carbon metabolism_Homo sapiens_hsa01200 | 0.43271816 |
| 86 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.41632795 |
| 87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40476134 |
| 88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.40073489 |
| 89 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.37310452 |
| 90 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.35326287 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.34848350 |
| 92 | Viral myocarditis_Homo sapiens_hsa05416 | 0.33971108 |
| 93 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.31884870 |
| 94 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.27834395 |
| 95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.26577856 |
| 96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26002341 |
| 97 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.25425063 |
| 98 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.24250983 |
| 99 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.24244493 |
| 100 | Salmonella infection_Homo sapiens_hsa05132 | 0.24153637 |

