

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neuron cell-cell adhesion (GO:0007158) | 8.23026989 |
| 2 | regulation of immunoglobulin secretion (GO:0051023) | 7.74016461 |
| 3 | positive regulation of macrophage activation (GO:0043032) | 6.95627799 |
| 4 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 6.46729782 |
| 5 | regulation of interleukin-13 production (GO:0032656) | 6.14988568 |
| 6 | positive regulation of chemokine secretion (GO:0090197) | 5.98669382 |
| 7 | negative regulation of cAMP-mediated signaling (GO:0043951) | 5.59095526 |
| 8 | L-methionine salvage (GO:0071267) | 5.40178650 |
| 9 | L-methionine biosynthetic process (GO:0071265) | 5.40178650 |
| 10 | amino acid salvage (GO:0043102) | 5.40178650 |
| 11 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 5.33739041 |
| 12 | microtubule nucleation (GO:0007020) | 5.32029981 |
| 13 | response to pheromone (GO:0019236) | 5.30921890 |
| 14 | regulation of chemokine secretion (GO:0090196) | 5.30829471 |
| 15 | atrial cardiac muscle cell action potential (GO:0086014) | 5.18700482 |
| 16 | base-excision repair, AP site formation (GO:0006285) | 5.15873342 |
| 17 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 5.04151628 |
| 18 | regulation of translation in response to stress (GO:0043555) | 4.94232054 |
| 19 | ER overload response (GO:0006983) | 4.88838732 |
| 20 | regulation of meiosis I (GO:0060631) | 4.79238177 |
| 21 | response to folic acid (GO:0051593) | 4.71061727 |
| 22 | primitive streak formation (GO:0090009) | 4.70924123 |
| 23 | toxin transport (GO:1901998) | 4.55532789 |
| 24 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 4.38148703 |
| 25 | secretory granule organization (GO:0033363) | 4.32262265 |
| 26 | single strand break repair (GO:0000012) | 4.24143962 |
| 27 | amino-acid betaine metabolic process (GO:0006577) | 4.20071383 |
| 28 | purine deoxyribonucleotide catabolic process (GO:0009155) | 4.16267928 |
| 29 | ribosomal small subunit assembly (GO:0000028) | 4.12911995 |
| 30 | methionine biosynthetic process (GO:0009086) | 4.08815521 |
| 31 | cell migration involved in gastrulation (GO:0042074) | 4.07483914 |
| 32 | centriole replication (GO:0007099) | 4.05673555 |
| 33 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.97055298 |
| 34 | protein carboxylation (GO:0018214) | 3.97055298 |
| 35 | positive regulation of type 2 immune response (GO:0002830) | 3.96328727 |
| 36 | regulation of macrophage activation (GO:0043030) | 3.90724735 |
| 37 | lysosome localization (GO:0032418) | 3.76365262 |
| 38 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 3.66743851 |
| 39 | platelet dense granule organization (GO:0060155) | 3.62477830 |
| 40 | otic vesicle formation (GO:0030916) | 3.47428169 |
| 41 | cellular response to cholesterol (GO:0071397) | 3.44275067 |
| 42 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.43390093 |
| 43 | positive regulation of interleukin-4 production (GO:0032753) | 3.42258494 |
| 44 | cellular response to sterol (GO:0036315) | 3.39531059 |
| 45 | positive regulation of immunoglobulin production (GO:0002639) | 3.39113113 |
| 46 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.38067630 |
| 47 | head development (GO:0060322) | 3.37887927 |
| 48 | GMP metabolic process (GO:0046037) | 3.37848105 |
| 49 | methionine metabolic process (GO:0006555) | 3.27278524 |
| 50 | aspartate family amino acid biosynthetic process (GO:0009067) | 3.24778664 |
| 51 | deoxyribonucleotide catabolic process (GO:0009264) | 3.21709200 |
| 52 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.20032662 |
| 53 | cell wall macromolecule catabolic process (GO:0016998) | 3.19292605 |
| 54 | negative regulation of leukocyte migration (GO:0002686) | 3.17104023 |
| 55 | radial glial cell differentiation (GO:0060019) | 3.16074217 |
| 56 | arginine catabolic process (GO:0006527) | 3.13568607 |
| 57 | positive regulation of meiosis (GO:0045836) | 3.13253020 |
| 58 | deoxyribose phosphate catabolic process (GO:0046386) | 3.09656741 |
| 59 | phosphatidylinositol phosphorylation (GO:0046854) | 3.08504645 |
| 60 | regulation of interleukin-5 production (GO:0032674) | 3.07134162 |
| 61 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 3.05687318 |
| 62 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.04327918 |
| 63 | regulation of mesenchymal cell apoptotic process (GO:2001053) | 3.00075153 |
| 64 | retinoic acid metabolic process (GO:0042573) | 2.99458860 |
| 65 | regulation of immunoglobulin production (GO:0002637) | 2.96812450 |
| 66 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.96411270 |
| 67 | regulation of phospholipase A2 activity (GO:0032429) | 2.94859681 |
| 68 | pyrimidine dimer repair (GO:0006290) | 2.93004803 |
| 69 | histone mRNA catabolic process (GO:0071044) | 2.92952419 |
| 70 | positive regulation of DNA recombination (GO:0045911) | 2.90968590 |
| 71 | positive regulation of meiotic cell cycle (GO:0051446) | 2.90418838 |
| 72 | embryonic viscerocranium morphogenesis (GO:0048703) | 2.89659447 |
| 73 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.82507901 |
| 74 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.82503977 |
| 75 | postreplication repair (GO:0006301) | 2.81129635 |
| 76 | cartilage morphogenesis (GO:0060536) | 2.80763908 |
| 77 | endoderm formation (GO:0001706) | 2.80485285 |
| 78 | rRNA catabolic process (GO:0016075) | 2.79590232 |
| 79 | dopamine transport (GO:0015872) | 2.79100015 |
| 80 | lipid phosphorylation (GO:0046834) | 2.78800204 |
| 81 | neuroblast proliferation (GO:0007405) | 2.77999533 |
| 82 | regulation of cell proliferation involved in heart morphogenesis (GO:2000136) | 2.76082097 |
| 83 | dopaminergic neuron differentiation (GO:0071542) | 2.75082364 |
| 84 | negative regulation of adaptive immune response (GO:0002820) | 2.75000139 |
| 85 | renal tubule morphogenesis (GO:0061333) | 2.74711060 |
| 86 | protein complex biogenesis (GO:0070271) | 2.71785347 |
| 87 | cellular response to ATP (GO:0071318) | 2.70903966 |
| 88 | sulfur amino acid biosynthetic process (GO:0000097) | 2.70744370 |
| 89 | protein heterotrimerization (GO:0070208) | 2.69649806 |
| 90 | genitalia morphogenesis (GO:0035112) | 2.66850833 |
| 91 | DNA demethylation (GO:0080111) | 2.66762712 |
| 92 | cell wall macromolecule metabolic process (GO:0044036) | 2.65082369 |
| 93 | positive regulation of heart rate (GO:0010460) | 2.63376974 |
| 94 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.62878002 |
| 95 | NADH dehydrogenase complex assembly (GO:0010257) | 2.62878002 |
| 96 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.62878002 |
| 97 | cardiovascular system development (GO:0072358) | 2.62837194 |
| 98 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.61099629 |
| 99 | regulation of smooth muscle cell apoptotic process (GO:0034391) | 2.58792397 |
| 100 | regulation of T-helper 1 type immune response (GO:0002825) | 2.58632425 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.85800156 |
| 2 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 3.31459796 |
| 3 | IRF1_19129219_ChIP-ChIP_H3396_Human | 3.23289898 |
| 4 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.21432569 |
| 5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.99830279 |
| 6 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.61804684 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.33357100 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.31994739 |
| 9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.22296707 |
| 10 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.07858768 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.07562044 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.05173920 |
| 13 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.01720382 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.00314535 |
| 15 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.94517343 |
| 16 | GATA1_22025678_ChIP-Seq_K562_Human | 1.86658607 |
| 17 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.86032072 |
| 18 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.79629246 |
| 19 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.75077404 |
| 20 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.71607866 |
| 21 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.71037795 |
| 22 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.64745233 |
| 23 | EWS_26573619_Chip-Seq_HEK293_Human | 1.63900212 |
| 24 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.63378570 |
| 25 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.51748582 |
| 26 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.47192348 |
| 27 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.44618407 |
| 28 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.37364790 |
| 29 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.37358647 |
| 30 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.36685273 |
| 31 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.35069890 |
| 32 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.32959782 |
| 33 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.32829160 |
| 34 | RARB_24833708_ChIP-Seq_LIVER_Mouse | 1.32345289 |
| 35 | ETV1_20927104_ChIP-Seq_GIST48_Human | 1.31394733 |
| 36 | ERA_21632823_ChIP-Seq_H3396_Human | 1.30805756 |
| 37 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.30040888 |
| 38 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.29071900 |
| 39 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.28966833 |
| 40 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.28657511 |
| 41 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.27161952 |
| 42 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.27161952 |
| 43 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.27056528 |
| 44 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.24369213 |
| 45 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.23721110 |
| 46 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.22216205 |
| 47 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.22051266 |
| 48 | NCOR_22424771_ChIP-Seq_293T_Human | 1.21331921 |
| 49 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.21044875 |
| 50 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.20462962 |
| 51 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.17482645 |
| 52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15665923 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15665923 |
| 54 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.15569111 |
| 55 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.15496036 |
| 56 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.15496036 |
| 57 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.15070561 |
| 58 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.14451652 |
| 59 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.12365831 |
| 60 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.10589784 |
| 61 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.09496333 |
| 62 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.08670272 |
| 63 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.07630918 |
| 64 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.07552089 |
| 65 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.07010268 |
| 66 | PHF8_20622853_ChIP-Seq_HELA_Human | 1.06556226 |
| 67 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.05991080 |
| 68 | FUS_26573619_Chip-Seq_HEK293_Human | 1.05666474 |
| 69 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.05504493 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.05296210 |
| 71 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.04715244 |
| 72 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.03884642 |
| 73 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.03667565 |
| 74 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.03507788 |
| 75 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.03470089 |
| 76 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.02380806 |
| 77 | CBX2_22325352_ChIP-Seq_293T-Rex_Human | 1.02294508 |
| 78 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 1.01992973 |
| 79 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.01892989 |
| 80 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.01860952 |
| 81 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.01506213 |
| 82 | P300_19829295_ChIP-Seq_ESCs_Human | 1.01412960 |
| 83 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01270239 |
| 84 | TCF4_23295773_ChIP-Seq_U87_Human | 1.00927696 |
| 85 | NFYB_21822215_ChIP-Seq_K562_Human | 1.00414787 |
| 86 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.00238724 |
| 87 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.99612027 |
| 88 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.99305369 |
| 89 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 0.98877053 |
| 90 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.98743082 |
| 91 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.98640803 |
| 92 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.98460110 |
| 93 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.98042905 |
| 94 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.98023931 |
| 95 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.97275522 |
| 96 | STAT3_23295773_ChIP-Seq_U87_Human | 0.96454876 |
| 97 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.96219617 |
| 98 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.96067187 |
| 99 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.96026409 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.95943923 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004885_abnormal_endolymph | 6.35164787 |
| 2 | MP0003283_abnormal_digestive_organ | 4.81817910 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.85854527 |
| 4 | MP0004742_abnormal_vestibular_system | 3.14332634 |
| 5 | MP0001440_abnormal_grooming_behavior | 2.61552194 |
| 6 | MP0003122_maternal_imprinting | 2.54034099 |
| 7 | MP0000015_abnormal_ear_pigmentation | 2.52285808 |
| 8 | MP0005075_abnormal_melanosome_morpholog | 2.41989431 |
| 9 | MP0002653_abnormal_ependyma_morphology | 2.25777449 |
| 10 | MP0002132_abnormal_respiratory_system | 2.25425418 |
| 11 | MP0002735_abnormal_chemical_nociception | 2.19586222 |
| 12 | MP0001485_abnormal_pinna_reflex | 2.13697072 |
| 13 | MP0002254_reproductive_system_inflammat | 2.12534346 |
| 14 | MP0003890_abnormal_embryonic-extraembry | 2.07643215 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.06693962 |
| 16 | MP0000049_abnormal_middle_ear | 1.90208107 |
| 17 | MP0001984_abnormal_olfaction | 1.89254051 |
| 18 | MP0006035_abnormal_mitochondrial_morpho | 1.88789919 |
| 19 | MP0008875_abnormal_xenobiotic_pharmacok | 1.87098906 |
| 20 | MP0004133_heterotaxia | 1.82216543 |
| 21 | MP0002095_abnormal_skin_pigmentation | 1.75422538 |
| 22 | MP0000566_synostosis | 1.72668345 |
| 23 | MP0003567_abnormal_fetal_cardiomyocyte | 1.71441159 |
| 24 | MP0005551_abnormal_eye_electrophysiolog | 1.65330167 |
| 25 | MP0002736_abnormal_nociception_after | 1.55395200 |
| 26 | MP0008872_abnormal_physiological_respon | 1.54379752 |
| 27 | MP0001968_abnormal_touch/_nociception | 1.48450211 |
| 28 | MP0006036_abnormal_mitochondrial_physio | 1.43344461 |
| 29 | MP0001727_abnormal_embryo_implantation | 1.37867235 |
| 30 | MP0000631_abnormal_neuroendocrine_gland | 1.36473537 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.35120393 |
| 32 | MP0008995_early_reproductive_senescence | 1.31405467 |
| 33 | MP0003121_genomic_imprinting | 1.30828173 |
| 34 | MP0002938_white_spotting | 1.30370639 |
| 35 | MP0006276_abnormal_autonomic_nervous | 1.29569343 |
| 36 | MP0004142_abnormal_muscle_tone | 1.29188877 |
| 37 | MP0005646_abnormal_pituitary_gland | 1.25933237 |
| 38 | MP0002557_abnormal_social/conspecific_i | 1.25683950 |
| 39 | MP0009764_decreased_sensitivity_to | 1.25148518 |
| 40 | MP0008789_abnormal_olfactory_epithelium | 1.24687268 |
| 41 | MP0002272_abnormal_nervous_system | 1.20163490 |
| 42 | MP0000026_abnormal_inner_ear | 1.20035561 |
| 43 | MP0001293_anophthalmia | 1.16932855 |
| 44 | MP0005084_abnormal_gallbladder_morpholo | 1.12229222 |
| 45 | MP0003646_muscle_fatigue | 1.10854339 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.09710186 |
| 47 | MP0001963_abnormal_hearing_physiology | 1.09476175 |
| 48 | MP0002638_abnormal_pupillary_reflex | 1.08206307 |
| 49 | MP0003880_abnormal_central_pattern | 1.07698210 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.05267364 |
| 51 | MP0002177_abnormal_outer_ear | 1.02195146 |
| 52 | MP0002102_abnormal_ear_morphology | 1.01964661 |
| 53 | MP0003635_abnormal_synaptic_transmissio | 0.97182092 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 0.95407344 |
| 55 | MP0000678_abnormal_parathyroid_gland | 0.95049597 |
| 56 | MP0003878_abnormal_ear_physiology | 0.94143425 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 0.94143425 |
| 58 | MP0005195_abnormal_posterior_eye | 0.93814418 |
| 59 | MP0001502_abnormal_circadian_rhythm | 0.92789313 |
| 60 | MP0004811_abnormal_neuron_physiology | 0.92456170 |
| 61 | MP0004859_abnormal_synaptic_plasticity | 0.92141531 |
| 62 | MP0002234_abnormal_pharynx_morphology | 0.91664822 |
| 63 | MP0001188_hyperpigmentation | 0.90360556 |
| 64 | MP0003698_abnormal_male_reproductive | 0.90209211 |
| 65 | MP0003123_paternal_imprinting | 0.90190456 |
| 66 | MP0009379_abnormal_foot_pigmentation | 0.89853009 |
| 67 | MP0008775_abnormal_heart_ventricle | 0.89353882 |
| 68 | MP0004019_abnormal_vitamin_homeostasis | 0.88510459 |
| 69 | MP0008058_abnormal_DNA_repair | 0.87932354 |
| 70 | MP0002752_abnormal_somatic_nervous | 0.86331786 |
| 71 | MP0002063_abnormal_learning/memory/cond | 0.86326777 |
| 72 | MP0005452_abnormal_adipose_tissue | 0.84973875 |
| 73 | MP0003195_calcinosis | 0.84437798 |
| 74 | MP0003252_abnormal_bile_duct | 0.83323488 |
| 75 | MP0003638_abnormal_response/metabolism_ | 0.82653954 |
| 76 | MP0005394_taste/olfaction_phenotype | 0.82465792 |
| 77 | MP0005499_abnormal_olfactory_system | 0.82465792 |
| 78 | MP0005645_abnormal_hypothalamus_physiol | 0.79941686 |
| 79 | MP0005389_reproductive_system_phenotype | 0.79518206 |
| 80 | MP0008569_lethality_at_weaning | 0.79085799 |
| 81 | MP0003787_abnormal_imprinting | 0.78916916 |
| 82 | MP0002160_abnormal_reproductive_system | 0.77906149 |
| 83 | MP0009745_abnormal_behavioral_response | 0.77423559 |
| 84 | MP0001324_abnormal_eye_pigmentation | 0.76209814 |
| 85 | MP0001764_abnormal_homeostasis | 0.75888143 |
| 86 | MP0002115_abnormal_skeleton_extremities | 0.75352411 |
| 87 | MP0003186_abnormal_redox_activity | 0.74870266 |
| 88 | MP0002009_preneoplasia | 0.74075825 |
| 89 | MP0003937_abnormal_limbs/digits/tail_de | 0.72184735 |
| 90 | MP0001765_abnormal_ion_homeostasis | 0.71852123 |
| 91 | MP0002572_abnormal_emotion/affect_behav | 0.69256822 |
| 92 | MP0003959_abnormal_lean_body | 0.67826231 |
| 93 | MP0002282_abnormal_trachea_morphology | 0.67688459 |
| 94 | MP0001905_abnormal_dopamine_level | 0.65700821 |
| 95 | MP0001486_abnormal_startle_reflex | 0.65371090 |
| 96 | MP0002229_neurodegeneration | 0.63883884 |
| 97 | MP0004043_abnormal_pH_regulation | 0.63761405 |
| 98 | MP0001270_distended_abdomen | 0.63427591 |
| 99 | MP0000778_abnormal_nervous_system | 0.61866622 |
| 100 | MP0002066_abnormal_motor_capabilities/c | 0.61705428 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Conjugated hyperbilirubinemia (HP:0002908) | 5.80708759 |
| 2 | Morphological abnormality of the inner ear (HP:0011390) | 4.31428279 |
| 3 | Rectal prolapse (HP:0002035) | 4.28289863 |
| 4 | Cerebral hypomyelination (HP:0006808) | 4.25442739 |
| 5 | Hip dysplasia (HP:0001385) | 4.19834106 |
| 6 | Congenital stationary night blindness (HP:0007642) | 4.12350009 |
| 7 | Entropion (HP:0000621) | 4.06622357 |
| 8 | Abnormality of the renal cortex (HP:0011035) | 3.93250169 |
| 9 | Abnormality of the right ventricle (HP:0001707) | 3.81169403 |
| 10 | Nephrogenic diabetes insipidus (HP:0009806) | 3.79610086 |
| 11 | Metabolic alkalosis (HP:0200114) | 3.61342433 |
| 12 | Polyuria (HP:0000103) | 3.57423184 |
| 13 | Tubulointerstitial fibrosis (HP:0005576) | 3.31159636 |
| 14 | Arthropathy (HP:0003040) | 3.26295920 |
| 15 | Renal salt wasting (HP:0000127) | 3.25090192 |
| 16 | Hypokalemic alkalosis (HP:0001949) | 3.23627971 |
| 17 | Thickened calvaria (HP:0002684) | 3.09788337 |
| 18 | Abnormality of the renal medulla (HP:0100957) | 3.07788296 |
| 19 | Morphological abnormality of the middle ear (HP:0008609) | 3.06777081 |
| 20 | Poikiloderma (HP:0001029) | 2.93843477 |
| 21 | Abnormality of incisor morphology (HP:0011063) | 2.92964905 |
| 22 | Abnormality of the labia minora (HP:0012880) | 2.90856502 |
| 23 | Abnormal urine output (HP:0012590) | 2.90546239 |
| 24 | Hypoplastic ischia (HP:0003175) | 2.90412076 |
| 25 | Hypomagnesemia (HP:0002917) | 2.87753449 |
| 26 | Cutaneous melanoma (HP:0012056) | 2.85266214 |
| 27 | Abnormality of the nasal septum (HP:0000419) | 2.84464600 |
| 28 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.80816038 |
| 29 | Absent/shortened dynein arms (HP:0200106) | 2.80816038 |
| 30 | True hermaphroditism (HP:0010459) | 2.74159552 |
| 31 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.73588963 |
| 32 | Squamous cell carcinoma (HP:0002860) | 2.66918626 |
| 33 | Vitreoretinal degeneration (HP:0000655) | 2.66370933 |
| 34 | Molar tooth sign on MRI (HP:0002419) | 2.65097333 |
| 35 | Abnormality of midbrain morphology (HP:0002418) | 2.65097333 |
| 36 | Oligodactyly (hands) (HP:0001180) | 2.63155776 |
| 37 | Abnormality of the 4th metacarpal (HP:0010012) | 2.56452455 |
| 38 | Unsteady gait (HP:0002317) | 2.53888517 |
| 39 | Pancreatic fibrosis (HP:0100732) | 2.52948152 |
| 40 | Tubulointerstitial abnormality (HP:0001969) | 2.41446952 |
| 41 | Abnormality of renal excretion (HP:0011036) | 2.38057720 |
| 42 | Alkalosis (HP:0001948) | 2.37828424 |
| 43 | Pancreatic cysts (HP:0001737) | 2.37750419 |
| 44 | Abnormality of magnesium homeostasis (HP:0004921) | 2.37363084 |
| 45 | Acute necrotizing encephalopathy (HP:0006965) | 2.36880701 |
| 46 | Hyponatremia (HP:0002902) | 2.35058332 |
| 47 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.32161380 |
| 48 | Abnormality of the ischium (HP:0003174) | 2.31703168 |
| 49 | Hepatocellular necrosis (HP:0001404) | 2.31216052 |
| 50 | CNS demyelination (HP:0007305) | 2.31147718 |
| 51 | Abnormality of chloride homeostasis (HP:0011422) | 2.30615397 |
| 52 | Hyperaldosteronism (HP:0000859) | 2.29533047 |
| 53 | Delusions (HP:0000746) | 2.29519203 |
| 54 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.29510171 |
| 55 | Hypoplasia of the fovea (HP:0007750) | 2.29077794 |
| 56 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.29077794 |
| 57 | Hypokalemia (HP:0002900) | 2.26243953 |
| 58 | Polyphagia (HP:0002591) | 2.25276109 |
| 59 | Small hand (HP:0200055) | 2.21384183 |
| 60 | Chorioretinal atrophy (HP:0000533) | 2.20941970 |
| 61 | Failure to thrive in infancy (HP:0001531) | 2.19961329 |
| 62 | Long clavicles (HP:0000890) | 2.19473218 |
| 63 | Mitochondrial inheritance (HP:0001427) | 2.17824391 |
| 64 | Nephronophthisis (HP:0000090) | 2.15883344 |
| 65 | Emotional lability (HP:0000712) | 2.15784370 |
| 66 | Chronic bronchitis (HP:0004469) | 2.15421961 |
| 67 | Irregular epiphyses (HP:0010582) | 2.12475040 |
| 68 | 11 pairs of ribs (HP:0000878) | 2.11204894 |
| 69 | Esotropia (HP:0000565) | 2.10135527 |
| 70 | Decreased subcutaneous fat (HP:0001002) | 2.08616993 |
| 71 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.07882779 |
| 72 | Abnormality of cochlea (HP:0000375) | 2.07834046 |
| 73 | Increased CSF lactate (HP:0002490) | 2.07539005 |
| 74 | Shawl scrotum (HP:0000049) | 2.05889895 |
| 75 | Volvulus (HP:0002580) | 2.02754539 |
| 76 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02656801 |
| 77 | Medial flaring of the eyebrow (HP:0010747) | 1.99422484 |
| 78 | Renal tubular acidosis (HP:0001947) | 1.98835949 |
| 79 | Fibular hypoplasia (HP:0003038) | 1.97959444 |
| 80 | Abnormality of DNA repair (HP:0003254) | 1.96830041 |
| 81 | Narrow forehead (HP:0000341) | 1.96516438 |
| 82 | Papilledema (HP:0001085) | 1.95919956 |
| 83 | Lissencephaly (HP:0001339) | 1.95511713 |
| 84 | Premature ovarian failure (HP:0008209) | 1.95037289 |
| 85 | Asplenia (HP:0001746) | 1.94997135 |
| 86 | Oligodactyly (HP:0012165) | 1.94235374 |
| 87 | Keratoconus (HP:0000563) | 1.94059329 |
| 88 | Increased corneal curvature (HP:0100692) | 1.94059329 |
| 89 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.93175227 |
| 90 | Febrile seizures (HP:0002373) | 1.91893843 |
| 91 | Short chin (HP:0000331) | 1.89993607 |
| 92 | Secondary amenorrhea (HP:0000869) | 1.88339040 |
| 93 | Pendular nystagmus (HP:0012043) | 1.87593594 |
| 94 | Abnormal EKG (HP:0003115) | 1.85164358 |
| 95 | Acute encephalopathy (HP:0006846) | 1.84919207 |
| 96 | Colon cancer (HP:0003003) | 1.84194960 |
| 97 | Abnormal number of erythroid precursors (HP:0012131) | 1.83930838 |
| 98 | Hepatic necrosis (HP:0002605) | 1.83229958 |
| 99 | Abnormality of potassium homeostasis (HP:0011042) | 1.81617655 |
| 100 | Neoplasm of the peripheral nervous system (HP:0100007) | 1.81428591 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NUAK1 | 5.72201135 |
| 2 | LATS1 | 4.54348068 |
| 3 | CASK | 3.59886222 |
| 4 | STK16 | 3.12758453 |
| 5 | MAPK12 | 2.90020372 |
| 6 | PINK1 | 2.85362964 |
| 7 | FGFR3 | 2.79706626 |
| 8 | ADRBK2 | 2.75092007 |
| 9 | EIF2AK1 | 2.15444256 |
| 10 | CDK3 | 2.13104641 |
| 11 | MARK3 | 2.03788708 |
| 12 | PBK | 1.98000747 |
| 13 | CCNB1 | 1.97075918 |
| 14 | CSNK1G1 | 1.86290910 |
| 15 | MAP4K2 | 1.84823830 |
| 16 | MAP2K2 | 1.75635689 |
| 17 | DAPK2 | 1.59732141 |
| 18 | STK4 | 1.56853492 |
| 19 | MST4 | 1.48974658 |
| 20 | AKT3 | 1.40328708 |
| 21 | EPHB2 | 1.40018033 |
| 22 | MAP2K6 | 1.22235410 |
| 23 | DMPK | 1.19242940 |
| 24 | BCKDK | 1.14175651 |
| 25 | NLK | 1.10986490 |
| 26 | PIM1 | 1.08439722 |
| 27 | TEC | 1.06163263 |
| 28 | PASK | 1.03318291 |
| 29 | PAK3 | 1.02808268 |
| 30 | MAPK13 | 1.00433949 |
| 31 | PRKD2 | 0.99070779 |
| 32 | FGFR1 | 0.94662855 |
| 33 | WNK3 | 0.94510770 |
| 34 | PNCK | 0.94390870 |
| 35 | WNK1 | 0.93371168 |
| 36 | INSRR | 0.93326134 |
| 37 | CDK19 | 0.93114158 |
| 38 | STK3 | 0.92415889 |
| 39 | TLK1 | 0.91256633 |
| 40 | MARK1 | 0.90650399 |
| 41 | FRK | 0.88936557 |
| 42 | WNK4 | 0.79960857 |
| 43 | DYRK1B | 0.77365868 |
| 44 | MAP3K11 | 0.75244163 |
| 45 | PHKG1 | 0.74422305 |
| 46 | PHKG2 | 0.74422305 |
| 47 | BMPR1B | 0.73223104 |
| 48 | MAP3K9 | 0.72127741 |
| 49 | GRK7 | 0.70782621 |
| 50 | STK10 | 0.70046767 |
| 51 | RPS6KA6 | 0.68263546 |
| 52 | MATK | 0.67541773 |
| 53 | UHMK1 | 0.63967218 |
| 54 | PIK3CA | 0.63362526 |
| 55 | IKBKB | 0.62957399 |
| 56 | CDC7 | 0.61982860 |
| 57 | WEE1 | 0.61604578 |
| 58 | TXK | 0.61554878 |
| 59 | GSK3A | 0.59644971 |
| 60 | RPS6KB2 | 0.57599663 |
| 61 | PRKCH | 0.54058197 |
| 62 | CSNK1G2 | 0.53990340 |
| 63 | MAPK7 | 0.53422268 |
| 64 | CAMK1 | 0.53256171 |
| 65 | IKBKE | 0.53008893 |
| 66 | CSNK1G3 | 0.52557909 |
| 67 | ITK | 0.52228508 |
| 68 | SIK3 | 0.51184318 |
| 69 | SGK494 | 0.50571366 |
| 70 | SGK223 | 0.50571366 |
| 71 | RPS6KL1 | 0.50062817 |
| 72 | RPS6KC1 | 0.50062817 |
| 73 | DYRK2 | 0.49522266 |
| 74 | KSR1 | 0.49058433 |
| 75 | GRK1 | 0.48702990 |
| 76 | ADRBK1 | 0.47877058 |
| 77 | CSNK1E | 0.47236190 |
| 78 | PRKCQ | 0.46018122 |
| 79 | PTK2B | 0.45733768 |
| 80 | FER | 0.44759320 |
| 81 | PRKCE | 0.42931470 |
| 82 | RIPK4 | 0.42060105 |
| 83 | AURKB | 0.41064078 |
| 84 | CSNK1A1 | 0.36915971 |
| 85 | MAP3K7 | 0.35241100 |
| 86 | KIT | 0.34964073 |
| 87 | OBSCN | 0.34845893 |
| 88 | RPS6KA1 | 0.33279380 |
| 89 | TAOK3 | 0.33166841 |
| 90 | PLK4 | 0.33134720 |
| 91 | PRKCI | 0.33132673 |
| 92 | PRKACA | 0.32552063 |
| 93 | BRSK2 | 0.32344860 |
| 94 | MAPK9 | 0.32260183 |
| 95 | CAMK1G | 0.31990065 |
| 96 | MAPK14 | 0.31465871 |
| 97 | DAPK3 | 0.31281384 |
| 98 | RPS6KB1 | 0.30827180 |
| 99 | OXSR1 | 0.30823263 |
| 100 | TGFBR1 | 0.30702237 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 7.59553559 |
| 2 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.32133827 |
| 3 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.92321665 |
| 4 | Phototransduction_Homo sapiens_hsa04744 | 2.82078344 |
| 5 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.32149733 |
| 6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.30952885 |
| 7 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.28442145 |
| 8 | Base excision repair_Homo sapiens_hsa03410 | 2.10795751 |
| 9 | Ribosome_Homo sapiens_hsa03010 | 2.10036969 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.06158859 |
| 11 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.03131620 |
| 12 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.82554897 |
| 13 | Proteasome_Homo sapiens_hsa03050 | 1.78666177 |
| 14 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.75362343 |
| 15 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.63498097 |
| 16 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.59615980 |
| 17 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.49645802 |
| 18 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.42612474 |
| 19 | Parkinsons disease_Homo sapiens_hsa05012 | 1.40434993 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.39079663 |
| 21 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.37071663 |
| 22 | Long-term depression_Homo sapiens_hsa04730 | 1.35195595 |
| 23 | Protein export_Homo sapiens_hsa03060 | 1.33736323 |
| 24 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.32201726 |
| 25 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.27739819 |
| 26 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.27500061 |
| 27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.25961727 |
| 28 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.24903429 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.24802383 |
| 30 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.23098391 |
| 31 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.16547997 |
| 32 | Retinol metabolism_Homo sapiens_hsa00830 | 1.16256015 |
| 33 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.15848489 |
| 34 | Taste transduction_Homo sapiens_hsa04742 | 1.13025504 |
| 35 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.11485908 |
| 36 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.11332091 |
| 37 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.10061558 |
| 38 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.09509644 |
| 39 | Nicotine addiction_Homo sapiens_hsa05033 | 1.09046421 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.08682033 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.07762984 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.03832653 |
| 43 | Homologous recombination_Homo sapiens_hsa03440 | 1.00141540 |
| 44 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.98271886 |
| 45 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.98161493 |
| 46 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.97067965 |
| 47 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.95822192 |
| 48 | Peroxisome_Homo sapiens_hsa04146 | 0.94045328 |
| 49 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.93455229 |
| 50 | Olfactory transduction_Homo sapiens_hsa04740 | 0.93046701 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.91047258 |
| 52 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.84196298 |
| 53 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.80629947 |
| 54 | Huntingtons disease_Homo sapiens_hsa05016 | 0.80174083 |
| 55 | Alzheimers disease_Homo sapiens_hsa05010 | 0.77086950 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.74817065 |
| 57 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.74317370 |
| 58 | Morphine addiction_Homo sapiens_hsa05032 | 0.73123508 |
| 59 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.69155844 |
| 60 | Salivary secretion_Homo sapiens_hsa04970 | 0.68591955 |
| 61 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68384800 |
| 62 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.68141014 |
| 63 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.68091533 |
| 64 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.63179955 |
| 65 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.61708000 |
| 66 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.59846742 |
| 67 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.57966841 |
| 68 | RNA transport_Homo sapiens_hsa03013 | 0.57627834 |
| 69 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.54301539 |
| 70 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.50945229 |
| 71 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48054680 |
| 72 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.47366103 |
| 73 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.45402288 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.43877376 |
| 75 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.42780888 |
| 76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.42574019 |
| 77 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.41439760 |
| 78 | Circadian entrainment_Homo sapiens_hsa04713 | 0.41231030 |
| 79 | Purine metabolism_Homo sapiens_hsa00230 | 0.39728517 |
| 80 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.37546563 |
| 81 | Mineral absorption_Homo sapiens_hsa04978 | 0.37255846 |
| 82 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.36540431 |
| 83 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.36274091 |
| 84 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.36015654 |
| 85 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.35141689 |
| 86 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.35020632 |
| 87 | RNA degradation_Homo sapiens_hsa03018 | 0.34721416 |
| 88 | Cocaine addiction_Homo sapiens_hsa05030 | 0.34689467 |
| 89 | RNA polymerase_Homo sapiens_hsa03020 | 0.33847065 |
| 90 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.32279099 |
| 91 | Insulin secretion_Homo sapiens_hsa04911 | 0.31119166 |
| 92 | Allograft rejection_Homo sapiens_hsa05330 | 0.30693897 |
| 93 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.30568444 |
| 94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.30329787 |
| 95 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.27870583 |
| 96 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.27129343 |
| 97 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.26944291 |
| 98 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.25291672 |
| 99 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.24287824 |
| 100 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.24195818 |

