

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Peyers patch development (GO:0048541) | 8.31964644 |
| 2 | mucosal-associated lymphoid tissue development (GO:0048537) | 8.31964644 |
| 3 | detection of light stimulus involved in visual perception (GO:0050908) | 7.30264357 |
| 4 | detection of light stimulus involved in sensory perception (GO:0050962) | 7.30264357 |
| 5 | regulation of chromatin binding (GO:0035561) | 6.09517255 |
| 6 | regulation of voltage-gated calcium channel activity (GO:1901385) | 5.36772181 |
| 7 | protein-chromophore linkage (GO:0018298) | 5.32063842 |
| 8 | serotonin metabolic process (GO:0042428) | 4.72668197 |
| 9 | behavioral response to nicotine (GO:0035095) | 4.65381487 |
| 10 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 4.64988589 |
| 11 | keratinocyte development (GO:0003334) | 4.62267102 |
| 12 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 4.51800953 |
| 13 | primary amino compound metabolic process (GO:1901160) | 4.49638162 |
| 14 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.47337760 |
| 15 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 4.36358199 |
| 16 | seminiferous tubule development (GO:0072520) | 4.06255813 |
| 17 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.99961161 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 3.99961161 |
| 19 | cellular ketone body metabolic process (GO:0046950) | 3.94699037 |
| 20 | activated T cell proliferation (GO:0050798) | 3.79251319 |
| 21 | DNA deamination (GO:0045006) | 3.69608623 |
| 22 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.58913915 |
| 23 | phosphatidylethanolamine acyl-chain remodeling (GO:0036152) | 3.57484138 |
| 24 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.53008657 |
| 25 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.53008657 |
| 26 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.50373533 |
| 27 | ketone body metabolic process (GO:1902224) | 3.48935549 |
| 28 | phosphatidylcholine acyl-chain remodeling (GO:0036151) | 3.44384287 |
| 29 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.43422004 |
| 30 | ribosomal small subunit assembly (GO:0000028) | 3.37666182 |
| 31 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.35961729 |
| 32 | spinal cord association neuron differentiation (GO:0021527) | 3.35033053 |
| 33 | synaptic transmission, glutamatergic (GO:0035249) | 3.28782404 |
| 34 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 3.25288010 |
| 35 | regulation of inositol phosphate biosynthetic process (GO:0010919) | 3.24570395 |
| 36 | Sertoli cell development (GO:0060009) | 3.10755668 |
| 37 | positive regulation of cAMP-mediated signaling (GO:0043950) | 3.09696624 |
| 38 | viral transcription (GO:0019083) | 3.07903114 |
| 39 | negative regulation of T cell differentiation in thymus (GO:0033085) | 3.06252188 |
| 40 | adult walking behavior (GO:0007628) | 3.02849961 |
| 41 | detection of mechanical stimulus involved in sensory perception (GO:0050974) | 3.02266410 |
| 42 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.02248256 |
| 43 | translational termination (GO:0006415) | 3.01702048 |
| 44 | neuronal action potential (GO:0019228) | 2.99882163 |
| 45 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.98633753 |
| 46 | behavioral response to ethanol (GO:0048149) | 2.97854083 |
| 47 | regulation of oxidative phosphorylation (GO:0002082) | 2.97361182 |
| 48 | protein complex biogenesis (GO:0070271) | 2.97063588 |
| 49 | histone-serine phosphorylation (GO:0035404) | 2.96364713 |
| 50 | ribosome biogenesis (GO:0042254) | 2.96007914 |
| 51 | mitochondrion morphogenesis (GO:0070584) | 2.95939824 |
| 52 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.94994064 |
| 53 | thymus development (GO:0048538) | 2.94748587 |
| 54 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.92544859 |
| 55 | spinal cord motor neuron differentiation (GO:0021522) | 2.91905529 |
| 56 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.91012683 |
| 57 | protein localization to cilium (GO:0061512) | 2.88897372 |
| 58 | mitochondrial RNA metabolic process (GO:0000959) | 2.86753709 |
| 59 | indole-containing compound metabolic process (GO:0042430) | 2.86467830 |
| 60 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.84000903 |
| 61 | respiratory chain complex IV assembly (GO:0008535) | 2.74581385 |
| 62 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.74553701 |
| 63 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.74553701 |
| 64 | NADH dehydrogenase complex assembly (GO:0010257) | 2.74553701 |
| 65 | cAMP metabolic process (GO:0046058) | 2.71660088 |
| 66 | response to acidic pH (GO:0010447) | 2.68670941 |
| 67 | cotranslational protein targeting to membrane (GO:0006613) | 2.67224069 |
| 68 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.66154146 |
| 69 | regulation of cellular respiration (GO:0043457) | 2.65088823 |
| 70 | forebrain neuron differentiation (GO:0021879) | 2.64795502 |
| 71 | protein targeting to ER (GO:0045047) | 2.63834912 |
| 72 | ventricular septum development (GO:0003281) | 2.63395632 |
| 73 | parturition (GO:0007567) | 2.60096762 |
| 74 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.59025073 |
| 75 | isotype switching (GO:0045190) | 2.59025073 |
| 76 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.59025073 |
| 77 | synaptic transmission, cholinergic (GO:0007271) | 2.58773611 |
| 78 | epithelial cilium movement (GO:0003351) | 2.58617519 |
| 79 | intracellular protein transmembrane import (GO:0044743) | 2.58067606 |
| 80 | cellular response to interferon-beta (GO:0035458) | 2.55445696 |
| 81 | adipose tissue development (GO:0060612) | 2.55375466 |
| 82 | ncRNA catabolic process (GO:0034661) | 2.55054130 |
| 83 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.54414735 |
| 84 | regulation of gene silencing by miRNA (GO:0060964) | 2.54414735 |
| 85 | regulation of gene silencing by RNA (GO:0060966) | 2.54414735 |
| 86 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.54317614 |
| 87 | cytochrome complex assembly (GO:0017004) | 2.53194861 |
| 88 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.52935730 |
| 89 | histone H4-K12 acetylation (GO:0043983) | 2.51838062 |
| 90 | positive regulation of mRNA catabolic process (GO:0061014) | 2.51756184 |
| 91 | kynurenine metabolic process (GO:0070189) | 2.51597942 |
| 92 | proteasome assembly (GO:0043248) | 2.51462640 |
| 93 | phosphatidylglycerol acyl-chain remodeling (GO:0036148) | 2.51030975 |
| 94 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.48922034 |
| 95 | rRNA catabolic process (GO:0016075) | 2.48781842 |
| 96 | protein localization to endoplasmic reticulum (GO:0070972) | 2.48460442 |
| 97 | skeletal muscle tissue regeneration (GO:0043403) | 2.47927176 |
| 98 | cellular component biogenesis (GO:0044085) | 2.47319148 |
| 99 | neuronal action potential propagation (GO:0019227) | 11.6700319 |
| 100 | gamma-aminobutyric acid transport (GO:0015812) | 10.5987014 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 8.69842347 |
| 2 | VDR_22108803_ChIP-Seq_LS180_Human | 3.66273185 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.44536087 |
| 4 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.35043042 |
| 5 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.96292917 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.65122672 |
| 7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.39234038 |
| 8 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.14812031 |
| 9 | EWS_26573619_Chip-Seq_HEK293_Human | 2.11937722 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.05464242 |
| 11 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.05346408 |
| 12 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.02916959 |
| 13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.01547897 |
| 14 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.96814577 |
| 15 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.92673184 |
| 16 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.86920028 |
| 17 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.85392010 |
| 18 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.84929055 |
| 19 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.82108103 |
| 20 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.82090972 |
| 21 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.80194682 |
| 22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.77109960 |
| 23 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.73562978 |
| 24 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.71143343 |
| 25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.65855485 |
| 26 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.60334452 |
| 27 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.59612048 |
| 28 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.59225759 |
| 29 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.55130394 |
| 30 | TP53_16413492_ChIP-PET_HCT116_Human | 1.55073250 |
| 31 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.49597261 |
| 32 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.46670190 |
| 33 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.46670190 |
| 34 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.46291419 |
| 35 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.45051027 |
| 36 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.44039302 |
| 37 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.43468276 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.42606249 |
| 39 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.41275443 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.40853841 |
| 41 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.38673514 |
| 42 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.35831652 |
| 43 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.32835293 |
| 44 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.31197140 |
| 45 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.27857445 |
| 46 | AR_25329375_ChIP-Seq_VCAP_Human | 1.26296514 |
| 47 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.26185935 |
| 48 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.24408909 |
| 49 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.22215186 |
| 50 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.22060599 |
| 51 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.21442691 |
| 52 | STAT3_23295773_ChIP-Seq_U87_Human | 1.17524433 |
| 53 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.16780667 |
| 54 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.16652219 |
| 55 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.16233999 |
| 56 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.15607194 |
| 57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.14898333 |
| 58 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.14072190 |
| 59 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.13559071 |
| 60 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.11981146 |
| 61 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.11953082 |
| 62 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11096721 |
| 63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11096721 |
| 64 | TCF4_23295773_ChIP-Seq_U87_Human | 1.10623692 |
| 65 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.10474153 |
| 66 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.09495876 |
| 67 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.09356203 |
| 68 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.08371818 |
| 69 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.06582508 |
| 70 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.05602664 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.04207957 |
| 72 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03733397 |
| 73 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.03598602 |
| 74 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.02836959 |
| 75 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.01925013 |
| 76 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.01080282 |
| 77 | FUS_26573619_Chip-Seq_HEK293_Human | 1.00662640 |
| 78 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.00506414 |
| 79 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.00222492 |
| 80 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.00100274 |
| 81 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.99253655 |
| 82 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.98581138 |
| 83 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98459805 |
| 84 | OCT1_27270436_Chip-Seq_PROSTATE_Human | 0.96960769 |
| 85 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.96679079 |
| 86 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.94276512 |
| 87 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.93419985 |
| 88 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.93106034 |
| 89 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.92951021 |
| 90 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.92147984 |
| 91 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.90196721 |
| 92 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.89732148 |
| 93 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.89707933 |
| 94 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 0.88240138 |
| 95 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.88233540 |
| 96 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.87293792 |
| 97 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.87026521 |
| 98 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.86800975 |
| 99 | GATA1_22025678_ChIP-Seq_K562_Human | 0.85494296 |
| 100 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84756132 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 3.98353984 |
| 2 | MP0008789_abnormal_olfactory_epithelium | 3.49225157 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 3.16443408 |
| 4 | MP0008877_abnormal_DNA_methylation | 2.91627653 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.89512271 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.84839360 |
| 7 | MP0003880_abnormal_central_pattern | 2.77192398 |
| 8 | MP0001529_abnormal_vocalization | 2.73021776 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.70498253 |
| 10 | MP0005499_abnormal_olfactory_system | 2.70498253 |
| 11 | MP0005671_abnormal_response_to | 2.60022830 |
| 12 | MP0009745_abnormal_behavioral_response | 2.50305627 |
| 13 | MP0001968_abnormal_touch/_nociception | 2.40822072 |
| 14 | MP0000631_abnormal_neuroendocrine_gland | 2.39620883 |
| 15 | MP0002736_abnormal_nociception_after | 2.24942213 |
| 16 | MP0003195_calcinosis | 2.24686383 |
| 17 | MP0005408_hypopigmentation | 2.23888162 |
| 18 | MP0002272_abnormal_nervous_system | 2.21142332 |
| 19 | MP0003315_abnormal_perineum_morphology | 2.17547907 |
| 20 | MP0009046_muscle_twitch | 2.16806778 |
| 21 | MP0005386_behavior/neurological_phenoty | 1.99074569 |
| 22 | MP0004924_abnormal_behavior | 1.99074569 |
| 23 | MP0005389_reproductive_system_phenotype | 1.96716180 |
| 24 | MP0001919_abnormal_reproductive_system | 1.96554711 |
| 25 | MP0009379_abnormal_foot_pigmentation | 1.96201580 |
| 26 | MP0005551_abnormal_eye_electrophysiolog | 1.94464060 |
| 27 | MP0001542_abnormal_bone_strength | 1.93830004 |
| 28 | MP0003646_muscle_fatigue | 1.89644658 |
| 29 | MP0005423_abnormal_somatic_nervous | 1.83305126 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.72626129 |
| 31 | MP0001486_abnormal_startle_reflex | 1.61654853 |
| 32 | MP0004142_abnormal_muscle_tone | 1.57620596 |
| 33 | MP0002160_abnormal_reproductive_system | 1.55781468 |
| 34 | MP0002837_dystrophic_cardiac_calcinosis | 1.53372084 |
| 35 | MP0004147_increased_porphyrin_level | 1.48284123 |
| 36 | MP0000685_abnormal_immune_system | 1.48104237 |
| 37 | MP0000639_abnormal_adrenal_gland | 1.46228014 |
| 38 | MP0005187_abnormal_penis_morphology | 1.45238369 |
| 39 | MP0003866_abnormal_defecation | 1.43110523 |
| 40 | MP0002067_abnormal_sensory_capabilities | 1.38855748 |
| 41 | MP0002572_abnormal_emotion/affect_behav | 1.36751542 |
| 42 | MP0002163_abnormal_gland_morphology | 1.35540027 |
| 43 | MP0002557_abnormal_social/conspecific_i | 1.35022696 |
| 44 | MP0004742_abnormal_vestibular_system | 1.31488684 |
| 45 | MP0002064_seizures | 1.28724565 |
| 46 | MP0004019_abnormal_vitamin_homeostasis | 1.26707478 |
| 47 | MP0008872_abnormal_physiological_respon | 1.26488625 |
| 48 | MP0001970_abnormal_pain_threshold | 1.21998741 |
| 49 | MP0002653_abnormal_ependyma_morphology | 1.21664130 |
| 50 | MP0002734_abnormal_mechanical_nocicepti | 1.16205051 |
| 51 | MP0002735_abnormal_chemical_nociception | 1.15275602 |
| 52 | MP0003693_abnormal_embryo_hatching | 1.13732375 |
| 53 | MP0003635_abnormal_synaptic_transmissio | 1.13085369 |
| 54 | MP0001440_abnormal_grooming_behavior | 1.12839035 |
| 55 | MP0002938_white_spotting | 1.10380387 |
| 56 | MP0005379_endocrine/exocrine_gland_phen | 1.07790949 |
| 57 | MP0005410_abnormal_fertilization | 1.07670532 |
| 58 | MP0001963_abnormal_hearing_physiology | 1.07296910 |
| 59 | MP0003878_abnormal_ear_physiology | 1.07083891 |
| 60 | MP0005377_hearing/vestibular/ear_phenot | 1.07083891 |
| 61 | MP0001986_abnormal_taste_sensitivity | 1.04117481 |
| 62 | MP0003806_abnormal_nucleotide_metabolis | 1.04059528 |
| 63 | MP0002638_abnormal_pupillary_reflex | 0.99026156 |
| 64 | MP0001485_abnormal_pinna_reflex | 0.98526255 |
| 65 | MP0001835_abnormal_antigen_presentation | 0.94141894 |
| 66 | MP0002733_abnormal_thermal_nociception | 0.92968866 |
| 67 | MP0001790_abnormal_immune_system | 0.92661715 |
| 68 | MP0005387_immune_system_phenotype | 0.92661715 |
| 69 | MP0001905_abnormal_dopamine_level | 0.92535711 |
| 70 | MP0002210_abnormal_sex_determination | 0.91439153 |
| 71 | MP0002277_abnormal_respiratory_mucosa | 0.91264783 |
| 72 | MP0000613_abnormal_salivary_gland | 0.91256088 |
| 73 | MP0003938_abnormal_ear_development | 0.90868443 |
| 74 | MP0005451_abnormal_body_composition | 0.90790799 |
| 75 | MP0003119_abnormal_digestive_system | 0.90116184 |
| 76 | MP0001873_stomach_inflammation | 0.89592158 |
| 77 | MP0002138_abnormal_hepatobiliary_system | 0.89416042 |
| 78 | MP0003698_abnormal_male_reproductive | 0.87291381 |
| 79 | MP0009764_decreased_sensitivity_to | 0.87258239 |
| 80 | MP0000372_irregular_coat_pigmentation | 0.85009760 |
| 81 | MP0002752_abnormal_somatic_nervous | 0.83914413 |
| 82 | MP0003136_yellow_coat_color | 0.81866189 |
| 83 | MP0002822_catalepsy | 0.81520162 |
| 84 | MP0001929_abnormal_gametogenesis | 0.81335940 |
| 85 | MP0000653_abnormal_sex_gland | 0.81023559 |
| 86 | MP0000026_abnormal_inner_ear | 0.80403353 |
| 87 | MP0002063_abnormal_learning/memory/cond | 0.79368008 |
| 88 | MP0003638_abnormal_response/metabolism_ | 0.79127093 |
| 89 | MP0003718_maternal_effect | 0.78255463 |
| 90 | MP0001119_abnormal_female_reproductive | 0.76157317 |
| 91 | MP0001293_anophthalmia | 0.74763838 |
| 92 | MP0005503_abnormal_tendon_morphology | 0.74012069 |
| 93 | MP0005647_abnormal_sex_gland | 0.73637657 |
| 94 | MP0005167_abnormal_blood-brain_barrier | 0.72928191 |
| 95 | MP0002184_abnormal_innervation | 0.72293615 |
| 96 | MP0001501_abnormal_sleep_pattern | 0.71629609 |
| 97 | MP0001800_abnormal_humoral_immune | 0.71216916 |
| 98 | MP0000049_abnormal_middle_ear | 0.69749624 |
| 99 | MP0003122_maternal_imprinting | 0.67386712 |
| 100 | MP0000566_synostosis | 0.67162631 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Bilateral sensorineural hearing impairment (HP:0008619) | 7.86982923 |
| 2 | Hyperventilation (HP:0002883) | 5.43160919 |
| 3 | Gaze-evoked nystagmus (HP:0000640) | 5.14642526 |
| 4 | Tinnitus (HP:0000360) | 4.68928331 |
| 5 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.40251558 |
| 6 | Tubular atrophy (HP:0000092) | 4.25319249 |
| 7 | Abnormality of dentin (HP:0010299) | 4.17349891 |
| 8 | Febrile seizures (HP:0002373) | 3.81432638 |
| 9 | Stomatitis (HP:0010280) | 3.77757099 |
| 10 | Abnormal drinking behavior (HP:0030082) | 3.69126719 |
| 11 | Polydipsia (HP:0001959) | 3.69126719 |
| 12 | 3-Methylglutaconic aciduria (HP:0003535) | 3.56876942 |
| 13 | Tubulointerstitial fibrosis (HP:0005576) | 3.42438634 |
| 14 | Inappropriate behavior (HP:0000719) | 3.29705528 |
| 15 | Congenital, generalized hypertrichosis (HP:0004540) | 3.16255289 |
| 16 | Dyskinesia (HP:0100660) | 3.16163385 |
| 17 | Abnormality of the renal cortex (HP:0011035) | 3.12044149 |
| 18 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.11614704 |
| 19 | Attenuation of retinal blood vessels (HP:0007843) | 2.93571385 |
| 20 | Pancreatic cysts (HP:0001737) | 2.90450494 |
| 21 | Acanthocytosis (HP:0001927) | 2.88614319 |
| 22 | Enlarged penis (HP:0000040) | 2.83828466 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.78295995 |
| 24 | Molar tooth sign on MRI (HP:0002419) | 2.78295995 |
| 25 | Nephronophthisis (HP:0000090) | 2.75075852 |
| 26 | Abnormality of the renal medulla (HP:0100957) | 2.74785851 |
| 27 | Atonic seizures (HP:0010819) | 2.68367058 |
| 28 | Decreased central vision (HP:0007663) | 2.66364625 |
| 29 | Polyuria (HP:0000103) | 2.64748891 |
| 30 | Hemiparesis (HP:0001269) | 2.62053219 |
| 31 | Drooling (HP:0002307) | 2.57007015 |
| 32 | Focal motor seizures (HP:0011153) | 2.55302635 |
| 33 | Abnormality of the dental pulp (HP:0006479) | 2.53413799 |
| 34 | Concave nail (HP:0001598) | 2.53013360 |
| 35 | Inability to walk (HP:0002540) | 2.52989637 |
| 36 | Acute necrotizing encephalopathy (HP:0006965) | 2.52082988 |
| 37 | Tubulointerstitial abnormality (HP:0001969) | 2.52034455 |
| 38 | Severe muscular hypotonia (HP:0006829) | 2.48610164 |
| 39 | Mitochondrial inheritance (HP:0001427) | 2.46841362 |
| 40 | Acute encephalopathy (HP:0006846) | 2.45380110 |
| 41 | Clumsiness (HP:0002312) | 2.41763426 |
| 42 | Medial flaring of the eyebrow (HP:0010747) | 2.40587719 |
| 43 | Small hand (HP:0200055) | 2.40224807 |
| 44 | Excessive salivation (HP:0003781) | 2.36563889 |
| 45 | Status epilepticus (HP:0002133) | 2.36419949 |
| 46 | Flat occiput (HP:0005469) | 2.35037509 |
| 47 | Focal seizures (HP:0007359) | 2.33866575 |
| 48 | Broad-based gait (HP:0002136) | 2.32075421 |
| 49 | Birth length less than 3rd percentile (HP:0003561) | 2.28803607 |
| 50 | Pendular nystagmus (HP:0012043) | 2.25363359 |
| 51 | Bile duct proliferation (HP:0001408) | 2.25326877 |
| 52 | Abnormal biliary tract physiology (HP:0012439) | 2.25326877 |
| 53 | Pancreatic fibrosis (HP:0100732) | 2.24967934 |
| 54 | Gonadotropin excess (HP:0000837) | 2.23138137 |
| 55 | Increased CSF lactate (HP:0002490) | 2.22176219 |
| 56 | Methylmalonic acidemia (HP:0002912) | 2.21356696 |
| 57 | Enlarged kidneys (HP:0000105) | 2.19824892 |
| 58 | Generalized myoclonic seizures (HP:0002123) | 2.19604160 |
| 59 | Abnormality of the diencephalon (HP:0010662) | 2.19387740 |
| 60 | Lipid accumulation in hepatocytes (HP:0006561) | 2.16698457 |
| 61 | Abnormal urine output (HP:0012590) | 2.16461455 |
| 62 | Fair hair (HP:0002286) | 2.16282503 |
| 63 | Increased hepatocellular lipid droplets (HP:0006565) | 2.15035631 |
| 64 | Poor eye contact (HP:0000817) | 2.13022632 |
| 65 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.12853237 |
| 66 | Bulbous nose (HP:0000414) | 2.12750537 |
| 67 | Hyperglycinemia (HP:0002154) | 2.11053326 |
| 68 | Adrenal hypoplasia (HP:0000835) | 2.08528287 |
| 69 | Abnormality of renal excretion (HP:0011036) | 2.04762975 |
| 70 | Optic disc pallor (HP:0000543) | 2.03124237 |
| 71 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.02019562 |
| 72 | Potter facies (HP:0002009) | 1.99908668 |
| 73 | Facial shape deformation (HP:0011334) | 1.99908668 |
| 74 | Protruding tongue (HP:0010808) | 1.99491732 |
| 75 | Abnormality of secondary sexual hair (HP:0009888) | 1.98066180 |
| 76 | Abnormality of the axillary hair (HP:0100134) | 1.98066180 |
| 77 | Progressive macrocephaly (HP:0004481) | 1.93770913 |
| 78 | Hypoplasia of the radius (HP:0002984) | 1.89768776 |
| 79 | Widely spaced teeth (HP:0000687) | 1.83875414 |
| 80 | Abnormality of homocysteine metabolism (HP:0010919) | 1.83221259 |
| 81 | Homocystinuria (HP:0002156) | 1.83221259 |
| 82 | Forearm undergrowth (HP:0009821) | 1.82881787 |
| 83 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.82369088 |
| 84 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.81755864 |
| 85 | Absent/shortened dynein arms (HP:0200106) | 1.81755864 |
| 86 | Cortical visual impairment (HP:0100704) | 1.81422576 |
| 87 | Progressive microcephaly (HP:0000253) | 1.80585946 |
| 88 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.78141088 |
| 89 | Abnormality of alanine metabolism (HP:0010916) | 1.78141088 |
| 90 | Hyperalaninemia (HP:0003348) | 1.78141088 |
| 91 | Hepatocellular necrosis (HP:0001404) | 1.76287983 |
| 92 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.74984305 |
| 93 | Disinhibition (HP:0000734) | 1.74247273 |
| 94 | Partial agenesis of the corpus callosum (HP:0001338) | 1.73343375 |
| 95 | Increased corneal curvature (HP:0100692) | 1.73109215 |
| 96 | Keratoconus (HP:0000563) | 1.73109215 |
| 97 | Asplenia (HP:0001746) | 1.72881820 |
| 98 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.72427693 |
| 99 | Fibular hypoplasia (HP:0003038) | 1.68805955 |
| 100 | Patellar aplasia (HP:0006443) | 1.67504960 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K9 | 4.64208748 |
| 2 | FRK | 3.66277096 |
| 3 | MKNK2 | 3.64101880 |
| 4 | MAP3K4 | 3.11232578 |
| 5 | MAP2K7 | 3.09259973 |
| 6 | ZAK | 2.87395453 |
| 7 | WNK4 | 2.86438535 |
| 8 | PIK3CA | 2.48826052 |
| 9 | PTK2B | 2.43257720 |
| 10 | GRK1 | 2.41219645 |
| 11 | AKT3 | 2.20685549 |
| 12 | SIK2 | 2.16606537 |
| 13 | TLK1 | 2.14492513 |
| 14 | ADRBK2 | 2.07093051 |
| 15 | TNIK | 1.86536011 |
| 16 | MKNK1 | 1.84914120 |
| 17 | BRAF | 1.72632063 |
| 18 | NEK1 | 1.70005843 |
| 19 | MAP3K6 | 1.66132597 |
| 20 | STK39 | 1.63641944 |
| 21 | MAP4K2 | 1.62407252 |
| 22 | NTRK2 | 1.61505009 |
| 23 | INSRR | 1.53904568 |
| 24 | OXSR1 | 1.46705024 |
| 25 | NTRK1 | 1.39304433 |
| 26 | BMPR1B | 1.34547446 |
| 27 | ARAF | 1.28689539 |
| 28 | PRKCG | 1.24719213 |
| 29 | LIMK1 | 1.21745366 |
| 30 | NEK2 | 1.16988485 |
| 31 | VRK1 | 0.98370681 |
| 32 | DAPK2 | 0.95445503 |
| 33 | RPS6KA6 | 0.92066401 |
| 34 | PKN1 | 0.90978946 |
| 35 | PLK4 | 0.90574018 |
| 36 | WNK3 | 0.89719569 |
| 37 | RPS6KA5 | 0.88804748 |
| 38 | PHKG1 | 0.85635020 |
| 39 | PHKG2 | 0.85635020 |
| 40 | NME1 | 0.84893061 |
| 41 | ADRBK1 | 0.82454929 |
| 42 | NUAK1 | 0.82418586 |
| 43 | CSNK1D | 0.81335180 |
| 44 | MOS | 0.79395516 |
| 45 | MAP2K4 | 0.77782906 |
| 46 | PDK2 | 0.77150452 |
| 47 | FES | 0.75710649 |
| 48 | CAMK4 | 0.75437881 |
| 49 | TNK2 | 0.73868895 |
| 50 | PASK | 0.72563609 |
| 51 | NTRK3 | 0.69727660 |
| 52 | PRKCQ | 0.68237479 |
| 53 | IKBKB | 0.67594502 |
| 54 | IKBKE | 0.67346953 |
| 55 | STK38 | 0.66590542 |
| 56 | MAPK13 | 0.64698206 |
| 57 | PRKD3 | 0.60343181 |
| 58 | KIT | 0.59116660 |
| 59 | CAMK1 | 0.59109627 |
| 60 | MARK1 | 0.58685287 |
| 61 | BTK | 0.58599677 |
| 62 | TAOK2 | 0.55714179 |
| 63 | SGK2 | 0.54799067 |
| 64 | BCKDK | 0.53252933 |
| 65 | CAMK2A | 0.51167504 |
| 66 | CAMKK2 | 0.50704748 |
| 67 | RPS6KB2 | 0.50131037 |
| 68 | DYRK3 | 0.49545102 |
| 69 | TXK | 0.48512743 |
| 70 | LYN | 0.46973442 |
| 71 | PLK1 | 0.46914452 |
| 72 | EIF2AK1 | 0.46777683 |
| 73 | PRKCD | 0.45336840 |
| 74 | DYRK2 | 0.44698178 |
| 75 | MAP2K2 | 0.44150800 |
| 76 | CAMK1D | 0.44142090 |
| 77 | CHEK2 | 0.42469334 |
| 78 | PRKCE | 0.42071779 |
| 79 | PINK1 | 0.41514332 |
| 80 | TYK2 | 0.40865063 |
| 81 | PRKACA | 0.39983165 |
| 82 | ATR | 0.39601823 |
| 83 | VRK2 | 0.38069573 |
| 84 | TAF1 | 0.37426149 |
| 85 | CASK | 0.36307725 |
| 86 | PLK2 | 0.35507362 |
| 87 | EPHA4 | 0.35053312 |
| 88 | CSNK2A1 | 0.34103659 |
| 89 | TGFBR1 | 0.33152900 |
| 90 | CAMK2D | 0.32609620 |
| 91 | CSNK1E | 0.32535995 |
| 92 | TIE1 | 0.31493376 |
| 93 | SGK3 | 0.31044117 |
| 94 | NEK9 | 0.30739866 |
| 95 | MUSK | 0.29741580 |
| 96 | MAP3K13 | 0.29468385 |
| 97 | SGK494 | 0.29451883 |
| 98 | SGK223 | 0.29451883 |
| 99 | CDC7 | 0.28351651 |
| 100 | GRK5 | 0.28094276 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 3.85048656 |
| 2 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 3.80034937 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.33939944 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.33878117 |
| 5 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.00315638 |
| 6 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.61995081 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.36153664 |
| 8 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.33006261 |
| 9 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 2.23993185 |
| 10 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.11412520 |
| 11 | Ether lipid metabolism_Homo sapiens_hsa00565 | 2.11279777 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.97605352 |
| 13 | Nicotine addiction_Homo sapiens_hsa05033 | 1.83819029 |
| 14 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.71550791 |
| 15 | Protein export_Homo sapiens_hsa03060 | 1.70713658 |
| 16 | RNA degradation_Homo sapiens_hsa03018 | 1.69990980 |
| 17 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.68709769 |
| 18 | Asthma_Homo sapiens_hsa05310 | 1.66445132 |
| 19 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.58683461 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.58330608 |
| 21 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 1.57038888 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.54064222 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.52379529 |
| 24 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.51983822 |
| 25 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.51555956 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.50714781 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.49785415 |
| 28 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.47727242 |
| 29 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.42968992 |
| 30 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.37128355 |
| 31 | Olfactory transduction_Homo sapiens_hsa04740 | 1.36698898 |
| 32 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.28938429 |
| 33 | Basal transcription factors_Homo sapiens_hsa03022 | 1.27158123 |
| 34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.21390383 |
| 35 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.19639728 |
| 36 | Proteasome_Homo sapiens_hsa03050 | 1.11391131 |
| 37 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.02946274 |
| 38 | Phototransduction_Homo sapiens_hsa04744 | 1.02024793 |
| 39 | Taste transduction_Homo sapiens_hsa04742 | 1.01681467 |
| 40 | Allograft rejection_Homo sapiens_hsa05330 | 0.95290961 |
| 41 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.95103367 |
| 42 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.90665988 |
| 43 | RNA polymerase_Homo sapiens_hsa03020 | 0.87065058 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 0.86914033 |
| 45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.85952815 |
| 46 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.85315319 |
| 47 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.84634143 |
| 48 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.83834692 |
| 49 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.83400737 |
| 50 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.82345017 |
| 51 | Long-term depression_Homo sapiens_hsa04730 | 0.82281131 |
| 52 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.81207016 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.78760405 |
| 54 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.78159413 |
| 55 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.72970491 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.72003906 |
| 57 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.71976639 |
| 58 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.71739627 |
| 59 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.71277162 |
| 60 | Peroxisome_Homo sapiens_hsa04146 | 0.69391411 |
| 61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.65790974 |
| 62 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.65291569 |
| 63 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.62047624 |
| 64 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.61753247 |
| 65 | Purine metabolism_Homo sapiens_hsa00230 | 0.60717102 |
| 66 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.60235809 |
| 67 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.60018729 |
| 68 | Circadian entrainment_Homo sapiens_hsa04713 | 0.58588927 |
| 69 | Cocaine addiction_Homo sapiens_hsa05030 | 0.58077629 |
| 70 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.56442798 |
| 71 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.53785932 |
| 72 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.53648187 |
| 73 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.53520036 |
| 74 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.53207834 |
| 75 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.52544917 |
| 76 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51159826 |
| 77 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.49333930 |
| 78 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.48777069 |
| 79 | Metabolic pathways_Homo sapiens_hsa01100 | 0.46568052 |
| 80 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.46333136 |
| 81 | Mineral absorption_Homo sapiens_hsa04978 | 0.45967952 |
| 82 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.45959750 |
| 83 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.45587299 |
| 84 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.44475003 |
| 85 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.44155278 |
| 86 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.42536272 |
| 87 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.40756219 |
| 88 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.40754882 |
| 89 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.40663529 |
| 90 | Circadian rhythm_Homo sapiens_hsa04710 | 0.40603742 |
| 91 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.39313657 |
| 92 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.38660053 |
| 93 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.38167039 |
| 94 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35823110 |
| 95 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33823243 |
| 96 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.33029822 |
| 97 | Spliceosome_Homo sapiens_hsa03040 | 0.32483636 |
| 98 | GABAergic synapse_Homo sapiens_hsa04727 | 0.31110456 |
| 99 | Insulin secretion_Homo sapiens_hsa04911 | 0.30439682 |
| 100 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.29592435 |

