

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.61901629 |
| 2 | cytidine deamination (GO:0009972) | 7.24150004 |
| 3 | cytidine metabolic process (GO:0046087) | 7.24150004 |
| 4 | cytidine catabolic process (GO:0006216) | 7.24150004 |
| 5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.63500532 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.27571937 |
| 7 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.70272456 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.56860311 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.49208852 |
| 10 | actin nucleation (GO:0045010) | 4.25173692 |
| 11 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 4.19717465 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.13890947 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.13890947 |
| 14 | positive thymic T cell selection (GO:0045059) | 3.91831308 |
| 15 | positive T cell selection (GO:0043368) | 3.79515196 |
| 16 | positive regulation of B cell differentiation (GO:0045579) | 3.78222909 |
| 17 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.75398045 |
| 18 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.73271192 |
| 19 | respiratory electron transport chain (GO:0022904) | 3.71655548 |
| 20 | protein complex biogenesis (GO:0070271) | 3.68820062 |
| 21 | electron transport chain (GO:0022900) | 3.64952164 |
| 22 | regulation of activation of Janus kinase activity (GO:0010533) | 3.60142911 |
| 23 | negative T cell selection (GO:0043383) | 3.58573093 |
| 24 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.52867990 |
| 25 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.43452359 |
| 26 | response to interferon-beta (GO:0035456) | 3.40197848 |
| 27 | deoxyribonucleotide catabolic process (GO:0009264) | 3.38314299 |
| 28 | negative regulation by host of viral transcription (GO:0043922) | 3.37386421 |
| 29 | negative regulation of B cell apoptotic process (GO:0002903) | 3.37329957 |
| 30 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.31211242 |
| 31 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.30817779 |
| 32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.28559638 |
| 33 | T cell migration (GO:0072678) | 3.26566917 |
| 34 | macrophage chemotaxis (GO:0048246) | 3.26086527 |
| 35 | ribosomal small subunit biogenesis (GO:0042274) | 3.26033293 |
| 36 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.24709481 |
| 37 | negative regulation of T cell apoptotic process (GO:0070233) | 3.23590375 |
| 38 | deoxyribose phosphate catabolic process (GO:0046386) | 3.23479677 |
| 39 | viral transcription (GO:0019083) | 3.23144214 |
| 40 | negative regulation of viral genome replication (GO:0045071) | 3.22006748 |
| 41 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.21400612 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.19411148 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.19411148 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.19411148 |
| 45 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.17572802 |
| 46 | sequestering of actin monomers (GO:0042989) | 3.15377966 |
| 47 | cytochrome complex assembly (GO:0017004) | 3.13562970 |
| 48 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.13399469 |
| 49 | positive regulation of T cell apoptotic process (GO:0070234) | 3.11115784 |
| 50 | translational termination (GO:0006415) | 3.10262510 |
| 51 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.09750612 |
| 52 | base-excision repair, AP site formation (GO:0006285) | 3.07808356 |
| 53 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.06928024 |
| 54 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.06839300 |
| 55 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.06548806 |
| 56 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.04938974 |
| 57 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.04507144 |
| 58 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.04220504 |
| 59 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.02197460 |
| 60 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.00647425 |
| 61 | chaperone-mediated protein transport (GO:0072321) | 3.00494737 |
| 62 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.98297120 |
| 63 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.98297120 |
| 64 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.97615562 |
| 65 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.95875384 |
| 66 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.95875384 |
| 67 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.95875384 |
| 68 | translational elongation (GO:0006414) | 2.95317999 |
| 69 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.94283882 |
| 70 | negative thymic T cell selection (GO:0045060) | 2.94041661 |
| 71 | protein targeting to ER (GO:0045047) | 2.93510054 |
| 72 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.93097911 |
| 73 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.93097911 |
| 74 | regulation of B cell differentiation (GO:0045577) | 2.91328675 |
| 75 | iron-sulfur cluster assembly (GO:0016226) | 2.90607337 |
| 76 | metallo-sulfur cluster assembly (GO:0031163) | 2.90607337 |
| 77 | cotranslational protein targeting to membrane (GO:0006613) | 2.89532863 |
| 78 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.89441130 |
| 79 | protein neddylation (GO:0045116) | 2.89185005 |
| 80 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.87920250 |
| 81 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.85838884 |
| 82 | positive regulation of cell killing (GO:0031343) | 2.84827518 |
| 83 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.84077523 |
| 84 | respiratory chain complex IV assembly (GO:0008535) | 2.83410536 |
| 85 | immunoglobulin mediated immune response (GO:0016064) | 2.82702339 |
| 86 | protein localization to endoplasmic reticulum (GO:0070972) | 2.81836403 |
| 87 | mannosylation (GO:0097502) | 2.81753190 |
| 88 | thymic T cell selection (GO:0045061) | 2.79430963 |
| 89 | mast cell activation involved in immune response (GO:0002279) | 2.79068768 |
| 90 | mast cell degranulation (GO:0043303) | 2.79068768 |
| 91 | eosinophil chemotaxis (GO:0048245) | 2.78972730 |
| 92 | positive regulation of prostaglandin secretion (GO:0032308) | 2.78646418 |
| 93 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.78318683 |
| 94 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.78318683 |
| 95 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.77545403 |
| 96 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.77167268 |
| 97 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.75058071 |
| 98 | maturation of SSU-rRNA (GO:0030490) | 2.73368587 |
| 99 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.72941052 |
| 100 | cytolysis (GO:0019835) | 2.72693915 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.96201929 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.15313655 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.91064212 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.34143162 |
| 5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.27782243 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.23039443 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.14725593 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.14272422 |
| 9 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.08274169 |
| 10 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.03422990 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.90750532 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.59620434 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.52273758 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.36638653 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.34002844 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.24955440 |
| 17 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.17261119 |
| 18 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.15321507 |
| 19 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 2.05663624 |
| 20 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.02849243 |
| 21 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.02359139 |
| 22 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.02050774 |
| 23 | MYB_26560356_Chip-Seq_TH2_Human | 2.01222628 |
| 24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.01136155 |
| 25 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.97389654 |
| 26 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.90026842 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.81419721 |
| 28 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.81300916 |
| 29 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.77443404 |
| 30 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.68047684 |
| 31 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.64362409 |
| 32 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.60315255 |
| 33 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.60030039 |
| 34 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.53513775 |
| 35 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.53480683 |
| 36 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.52982062 |
| 37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.49674625 |
| 38 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.47210072 |
| 39 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.46777538 |
| 40 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.41757391 |
| 41 | UTX_26944678_Chip-Seq_JUKART_Human | 1.40978036 |
| 42 | GATA3_26560356_Chip-Seq_TH2_Human | 1.40832634 |
| 43 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.39077490 |
| 44 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.36284803 |
| 45 | MYB_26560356_Chip-Seq_TH1_Human | 1.34179323 |
| 46 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.33127209 |
| 47 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.32418140 |
| 48 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.29911036 |
| 49 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.28890042 |
| 50 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.27841912 |
| 51 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.26288557 |
| 52 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.26038514 |
| 53 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.24855743 |
| 54 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.24666859 |
| 55 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.24143837 |
| 56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.22329290 |
| 57 | MAF_26560356_Chip-Seq_TH2_Human | 1.22115015 |
| 58 | VDR_22108803_ChIP-Seq_LS180_Human | 1.21244601 |
| 59 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.18944936 |
| 60 | P300_27268052_Chip-Seq_Bcells_Human | 1.17768839 |
| 61 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.17157233 |
| 62 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.16840207 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.14487596 |
| 64 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.14395963 |
| 65 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.14271987 |
| 66 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.13509518 |
| 67 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.13406236 |
| 68 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.12633148 |
| 69 | AR_20517297_ChIP-Seq_VCAP_Human | 1.11026985 |
| 70 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.10247261 |
| 71 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.09932505 |
| 72 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.09293075 |
| 73 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07721975 |
| 74 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.06499625 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.05426953 |
| 76 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04047703 |
| 77 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.02192578 |
| 78 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02111914 |
| 79 | MAF_26560356_Chip-Seq_TH1_Human | 1.00629606 |
| 80 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.98442230 |
| 81 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.97525166 |
| 82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97195465 |
| 83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97195465 |
| 84 | NCOR_22424771_ChIP-Seq_293T_Human | 0.95758296 |
| 85 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.95586867 |
| 86 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95456415 |
| 87 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.94832075 |
| 88 | E2F1_20622854_ChIP-Seq_HELA_Human | 0.94747794 |
| 89 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.93480418 |
| 90 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.92893830 |
| 91 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92509625 |
| 92 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.92471432 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.91428705 |
| 94 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.91415697 |
| 95 | ERA_21632823_ChIP-Seq_H3396_Human | 0.91356462 |
| 96 | SA1_27219007_Chip-Seq_Bcells_Human | 0.88686460 |
| 97 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.87879737 |
| 98 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.87403567 |
| 99 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.86926497 |
| 100 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.84949198 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.23179752 |
| 2 | MP0001835_abnormal_antigen_presentation | 3.19087788 |
| 3 | MP0005645_abnormal_hypothalamus_physiol | 2.85763833 |
| 4 | MP0009785_altered_susceptibility_to | 2.80419881 |
| 5 | MP0003763_abnormal_thymus_physiology | 2.58293947 |
| 6 | MP0009333_abnormal_splenocyte_physiolog | 2.57765943 |
| 7 | MP0000372_irregular_coat_pigmentation | 2.40316858 |
| 8 | MP0002148_abnormal_hypersensitivity_rea | 2.37904864 |
| 9 | MP0004147_increased_porphyrin_level | 2.37854942 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.36863506 |
| 11 | MP0001800_abnormal_humoral_immune | 2.26967649 |
| 12 | MP0005025_abnormal_response_to | 2.25635315 |
| 13 | MP0000685_abnormal_immune_system | 2.24523896 |
| 14 | MP0009379_abnormal_foot_pigmentation | 2.16606694 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.13881368 |
| 16 | MP0001819_abnormal_immune_cell | 2.07067944 |
| 17 | MP0005387_immune_system_phenotype | 2.05035017 |
| 18 | MP0001790_abnormal_immune_system | 2.05035017 |
| 19 | MP0002723_abnormal_immune_serum | 2.03109243 |
| 20 | MP0003806_abnormal_nucleotide_metabolis | 2.01594340 |
| 21 | MP0001873_stomach_inflammation | 1.96611335 |
| 22 | MP0005075_abnormal_melanosome_morpholog | 1.96566243 |
| 23 | MP0002452_abnormal_antigen_presenting | 1.78029347 |
| 24 | MP0003646_muscle_fatigue | 1.77268512 |
| 25 | MP0006082_CNS_inflammation | 1.70746092 |
| 26 | MP0002398_abnormal_bone_marrow | 1.68613260 |
| 27 | MP0000716_abnormal_immune_system | 1.67360209 |
| 28 | MP0006292_abnormal_olfactory_placode | 1.62196539 |
| 29 | MP0008872_abnormal_physiological_respon | 1.60771869 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.56886752 |
| 31 | MP0003866_abnormal_defecation | 1.53854811 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.50156045 |
| 33 | MP0001905_abnormal_dopamine_level | 1.46469756 |
| 34 | MP0000689_abnormal_spleen_morphology | 1.43619241 |
| 35 | MP0002102_abnormal_ear_morphology | 1.43500302 |
| 36 | MP0002405_respiratory_system_inflammati | 1.39994038 |
| 37 | MP0002722_abnormal_immune_system | 1.36803132 |
| 38 | MP0008058_abnormal_DNA_repair | 1.34813233 |
| 39 | MP0003786_premature_aging | 1.34747262 |
| 40 | MP0002419_abnormal_innate_immunity | 1.34363736 |
| 41 | MP0002429_abnormal_blood_cell | 1.32982712 |
| 42 | MP0002837_dystrophic_cardiac_calcinosis | 1.32898405 |
| 43 | MP0002163_abnormal_gland_morphology | 1.32042235 |
| 44 | MP0005084_abnormal_gallbladder_morpholo | 1.31507366 |
| 45 | MP0002138_abnormal_hepatobiliary_system | 1.30675550 |
| 46 | MP0006072_abnormal_retinal_apoptosis | 1.29441660 |
| 47 | MP0002006_tumorigenesis | 1.28669679 |
| 48 | MP0005464_abnormal_platelet_physiology | 1.28501003 |
| 49 | MP0006036_abnormal_mitochondrial_physio | 1.27124378 |
| 50 | MP0001845_abnormal_inflammatory_respons | 1.26820934 |
| 51 | MP0001853_heart_inflammation | 1.26212302 |
| 52 | MP0000703_abnormal_thymus_morphology | 1.22734886 |
| 53 | MP0002638_abnormal_pupillary_reflex | 1.21712917 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.20811199 |
| 55 | MP0005646_abnormal_pituitary_gland | 1.17935583 |
| 56 | MP0001919_abnormal_reproductive_system | 1.17145558 |
| 57 | MP0003436_decreased_susceptibility_to | 1.16955868 |
| 58 | MP0005389_reproductive_system_phenotype | 1.16548536 |
| 59 | MP0010155_abnormal_intestine_physiology | 1.15744619 |
| 60 | MP0005551_abnormal_eye_electrophysiolog | 1.15138609 |
| 61 | MP0005083_abnormal_biliary_tract | 1.14099626 |
| 62 | MP0008877_abnormal_DNA_methylation | 1.13605015 |
| 63 | MP0002095_abnormal_skin_pigmentation | 1.11600440 |
| 64 | MP0004142_abnormal_muscle_tone | 1.07881276 |
| 65 | MP0005410_abnormal_fertilization | 1.07745881 |
| 66 | MP0003787_abnormal_imprinting | 1.06449412 |
| 67 | MP0002019_abnormal_tumor_incidence | 1.01232218 |
| 68 | MP0008469_abnormal_protein_level | 1.00357690 |
| 69 | MP0009643_abnormal_urine_homeostasis | 0.94629777 |
| 70 | MP0000465_gastrointestinal_hemorrhage | 0.93833018 |
| 71 | MP0002933_joint_inflammation | 0.93601165 |
| 72 | MP0002876_abnormal_thyroid_physiology | 0.92031869 |
| 73 | MP0005636_abnormal_mineral_homeostasis | 0.91642544 |
| 74 | MP0009763_increased_sensitivity_to | 0.91631907 |
| 75 | MP0001485_abnormal_pinna_reflex | 0.91189726 |
| 76 | MP0003252_abnormal_bile_duct | 0.90597836 |
| 77 | MP0003878_abnormal_ear_physiology | 0.90569820 |
| 78 | MP0005377_hearing/vestibular/ear_phenot | 0.90569820 |
| 79 | MP0008995_early_reproductive_senescence | 0.90421209 |
| 80 | MP0006276_abnormal_autonomic_nervous | 0.89665985 |
| 81 | MP0001764_abnormal_homeostasis | 0.89603767 |
| 82 | MP0002693_abnormal_pancreas_physiology | 0.88927139 |
| 83 | MP0002160_abnormal_reproductive_system | 0.88450674 |
| 84 | MP0001968_abnormal_touch/_nociception | 0.86200766 |
| 85 | MP0003186_abnormal_redox_activity | 0.83802549 |
| 86 | MP0002277_abnormal_respiratory_mucosa | 0.83455042 |
| 87 | MP0003011_delayed_dark_adaptation | 0.81927497 |
| 88 | MP0010386_abnormal_urinary_bladder | 0.79395249 |
| 89 | MP0004043_abnormal_pH_regulation | 0.78031019 |
| 90 | MP0003195_calcinosis | 0.77828286 |
| 91 | MP0005379_endocrine/exocrine_gland_phen | 0.77277855 |
| 92 | MP0005166_decreased_susceptibility_to | 0.75773254 |
| 93 | MP0005253_abnormal_eye_physiology | 0.75422139 |
| 94 | MP0009764_decreased_sensitivity_to | 0.73425809 |
| 95 | MP0004742_abnormal_vestibular_system | 0.73177323 |
| 96 | MP0002653_abnormal_ependyma_morphology | 0.72239345 |
| 97 | MP0001119_abnormal_female_reproductive | 0.69241696 |
| 98 | MP0008873_increased_physiological_sensi | 0.67383065 |
| 99 | MP0003448_altered_tumor_morphology | 0.66274319 |
| 100 | MP0003075_altered_response_to | 0.65840253 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 4.67625201 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.52790061 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.28034349 |
| 4 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.14808214 |
| 5 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.06341667 |
| 6 | Hepatocellular necrosis (HP:0001404) | 3.98837268 |
| 7 | Increased CSF lactate (HP:0002490) | 3.83461201 |
| 8 | Increased intramyocellular lipid droplets (HP:0012240) | 3.74561243 |
| 9 | IgG deficiency (HP:0004315) | 3.70896820 |
| 10 | Agammaglobulinemia (HP:0004432) | 3.66591773 |
| 11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.59735165 |
| 12 | Acute encephalopathy (HP:0006846) | 3.55744540 |
| 13 | 3-Methylglutaconic aciduria (HP:0003535) | 3.51518089 |
| 14 | Hepatic necrosis (HP:0002605) | 3.51253706 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 3.49700694 |
| 16 | Progressive macrocephaly (HP:0004481) | 3.44630960 |
| 17 | Autoimmune hemolytic anemia (HP:0001890) | 3.39582607 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.32407853 |
| 19 | T lymphocytopenia (HP:0005403) | 3.30883066 |
| 20 | Abnormality of T cell number (HP:0011839) | 3.28574829 |
| 21 | Lipid accumulation in hepatocytes (HP:0006561) | 3.26302647 |
| 22 | Hypoproteinemia (HP:0003075) | 3.24652572 |
| 23 | Abnormality of the prostate (HP:0008775) | 3.21335770 |
| 24 | Congenital stationary night blindness (HP:0007642) | 3.20319677 |
| 25 | Increased muscle lipid content (HP:0009058) | 3.20073690 |
| 26 | Abnormality of B cell number (HP:0010975) | 3.17808559 |
| 27 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.10354961 |
| 28 | Increased IgM level (HP:0003496) | 3.07568733 |
| 29 | Cerebral edema (HP:0002181) | 3.07297461 |
| 30 | B lymphocytopenia (HP:0010976) | 2.96719893 |
| 31 | Abnormality of T cells (HP:0002843) | 2.89505435 |
| 32 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.77560166 |
| 33 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.77560166 |
| 34 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.76997218 |
| 35 | Obstructive lung disease (HP:0006536) | 2.72096403 |
| 36 | Chronic obstructive pulmonary disease (HP:0006510) | 2.72096403 |
| 37 | Combined immunodeficiency (HP:0005387) | 2.65011604 |
| 38 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.61327710 |
| 39 | Meningitis (HP:0001287) | 2.61011975 |
| 40 | Exertional dyspnea (HP:0002875) | 2.59933046 |
| 41 | Severe visual impairment (HP:0001141) | 2.56795690 |
| 42 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.54967700 |
| 43 | Cerebral palsy (HP:0100021) | 2.51876676 |
| 44 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.47098917 |
| 45 | Optic disc pallor (HP:0000543) | 2.46550009 |
| 46 | Abnormal number of erythroid precursors (HP:0012131) | 2.46161607 |
| 47 | Pancytopenia (HP:0001876) | 2.45308948 |
| 48 | Thyroiditis (HP:0100646) | 2.44759031 |
| 49 | Abnormality of eosinophils (HP:0001879) | 2.44282176 |
| 50 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.42788169 |
| 51 | Lactic acidosis (HP:0003128) | 2.42107476 |
| 52 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.40962372 |
| 53 | Increased serum lactate (HP:0002151) | 2.40379858 |
| 54 | Exercise intolerance (HP:0003546) | 2.38675506 |
| 55 | Panhypogammaglobulinemia (HP:0003139) | 2.36738562 |
| 56 | Stomatitis (HP:0010280) | 2.31835714 |
| 57 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.30304442 |
| 58 | Dicarboxylic aciduria (HP:0003215) | 2.30304442 |
| 59 | Type I transferrin isoform profile (HP:0003642) | 2.26554964 |
| 60 | Respiratory failure (HP:0002878) | 2.22045738 |
| 61 | Reduced antithrombin III activity (HP:0001976) | 2.19108972 |
| 62 | Encephalitis (HP:0002383) | 2.18626931 |
| 63 | Eosinophilia (HP:0001880) | 2.15750735 |
| 64 | Reticulocytopenia (HP:0001896) | 2.13975710 |
| 65 | Lethargy (HP:0001254) | 2.08238252 |
| 66 | Skin rash (HP:0000988) | 2.07372016 |
| 67 | Lymphopenia (HP:0001888) | 2.06996537 |
| 68 | Recurrent bronchitis (HP:0002837) | 2.06788718 |
| 69 | Recurrent fungal infections (HP:0002841) | 2.05394078 |
| 70 | Abnormality of T cell physiology (HP:0011840) | 2.05115403 |
| 71 | Methylmalonic aciduria (HP:0012120) | 2.04975763 |
| 72 | Abnormal albumin level (HP:0012116) | 2.04897675 |
| 73 | Hypoalbuminemia (HP:0003073) | 2.04897675 |
| 74 | Chronic diarrhea (HP:0002028) | 2.04334182 |
| 75 | Abnormality of midbrain morphology (HP:0002418) | 2.03210743 |
| 76 | Molar tooth sign on MRI (HP:0002419) | 2.03210743 |
| 77 | Pancreatic cysts (HP:0001737) | 2.00025744 |
| 78 | Decreased central vision (HP:0007663) | 1.95445578 |
| 79 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.94988878 |
| 80 | Leukocytosis (HP:0001974) | 1.94593477 |
| 81 | Oral leukoplakia (HP:0002745) | 1.94122232 |
| 82 | Attenuation of retinal blood vessels (HP:0007843) | 1.94090930 |
| 83 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93310679 |
| 84 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93310679 |
| 85 | Abnormal protein glycosylation (HP:0012346) | 1.93310679 |
| 86 | Abnormal glycosylation (HP:0012345) | 1.93310679 |
| 87 | Abnormality of renal resorption (HP:0011038) | 1.92780463 |
| 88 | Recurrent cutaneous fungal infections (HP:0011370) | 1.91793268 |
| 89 | Chronic mucocutaneous candidiasis (HP:0002728) | 1.91793268 |
| 90 | Absent thumb (HP:0009777) | 1.91125888 |
| 91 | Respiratory difficulties (HP:0002880) | 1.89436029 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 1.89277593 |
| 93 | Abolished electroretinogram (ERG) (HP:0000550) | 1.87507149 |
| 94 | Hypergammaglobulinemia (HP:0010702) | 1.87450212 |
| 95 | Mediastinal lymphadenopathy (HP:0100721) | 1.86272475 |
| 96 | Recurrent viral infections (HP:0004429) | 1.86263053 |
| 97 | Granulocytopenia (HP:0001913) | 1.85246969 |
| 98 | Abnormality of male internal genitalia (HP:0000022) | 1.84088719 |
| 99 | Prostate neoplasm (HP:0100787) | 1.83907591 |
| 100 | Microvesicular hepatic steatosis (HP:0001414) | 1.81393517 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 5.43279697 |
| 2 | TESK2 | 5.39486502 |
| 3 | VRK2 | 4.28293475 |
| 4 | TXK | 3.99560872 |
| 5 | BCKDK | 3.75217521 |
| 6 | MAP4K1 | 2.46852489 |
| 7 | SCYL2 | 2.17279552 |
| 8 | MAP3K11 | 2.14786011 |
| 9 | VRK1 | 2.05601668 |
| 10 | TESK1 | 1.91184573 |
| 11 | TAOK3 | 1.90638185 |
| 12 | NUAK1 | 1.90170867 |
| 13 | LIMK1 | 1.88529655 |
| 14 | ZAK | 1.86730235 |
| 15 | MAP3K12 | 1.82940250 |
| 16 | ADRBK2 | 1.73659327 |
| 17 | GRK1 | 1.71539272 |
| 18 | MAP4K2 | 1.64070876 |
| 19 | TLK1 | 1.59619128 |
| 20 | ITK | 1.58892685 |
| 21 | SYK | 1.56084658 |
| 22 | PIM2 | 1.52957762 |
| 23 | KIT | 1.45282761 |
| 24 | TAF1 | 1.33396773 |
| 25 | TEC | 1.25836889 |
| 26 | TNK2 | 1.25061209 |
| 27 | MST4 | 1.22264988 |
| 28 | FES | 1.19840187 |
| 29 | CCNB1 | 1.18336306 |
| 30 | GRK6 | 1.15551079 |
| 31 | PRKCQ | 1.12599087 |
| 32 | DAPK1 | 1.11414347 |
| 33 | BTK | 1.09766953 |
| 34 | CDK19 | 1.06326633 |
| 35 | NME2 | 1.01918208 |
| 36 | LCK | 0.94300576 |
| 37 | BUB1 | 0.93073709 |
| 38 | MUSK | 0.92942148 |
| 39 | GRK7 | 0.92865630 |
| 40 | LRRK2 | 0.89876458 |
| 41 | IKBKB | 0.87819829 |
| 42 | RPS6KA5 | 0.83021323 |
| 43 | MAPKAPK3 | 0.82762021 |
| 44 | PIK3CG | 0.79031856 |
| 45 | DAPK3 | 0.78263267 |
| 46 | AURKA | 0.77842391 |
| 47 | TIE1 | 0.77417185 |
| 48 | IKBKE | 0.76477087 |
| 49 | LYN | 0.75649283 |
| 50 | WNK4 | 0.73714791 |
| 51 | CSK | 0.72374103 |
| 52 | CSF1R | 0.68406122 |
| 53 | DYRK2 | 0.66687519 |
| 54 | STK16 | 0.66652935 |
| 55 | CAMKK2 | 0.66545613 |
| 56 | MYLK | 0.65990150 |
| 57 | ZAP70 | 0.65734604 |
| 58 | INSRR | 0.65086514 |
| 59 | TBK1 | 0.62421823 |
| 60 | MATK | 0.62272624 |
| 61 | ARAF | 0.61012804 |
| 62 | PIM1 | 0.59848864 |
| 63 | NEK2 | 0.57654571 |
| 64 | MAPKAPK5 | 0.57560242 |
| 65 | IRAK4 | 0.57508416 |
| 66 | PINK1 | 0.56862751 |
| 67 | ABL2 | 0.56492646 |
| 68 | BMPR1B | 0.55318793 |
| 69 | GRK5 | 0.53535794 |
| 70 | JAK3 | 0.53276747 |
| 71 | OXSR1 | 0.51940668 |
| 72 | MAPK13 | 0.50240742 |
| 73 | ADRBK1 | 0.46954397 |
| 74 | WNK3 | 0.45665188 |
| 75 | PASK | 0.45579908 |
| 76 | ILK | 0.45574183 |
| 77 | FRK | 0.44989825 |
| 78 | TRPM7 | 0.44208227 |
| 79 | CDK8 | 0.43035496 |
| 80 | DAPK2 | 0.42616502 |
| 81 | NME1 | 0.41835490 |
| 82 | MAP2K6 | 0.41247672 |
| 83 | OBSCN | 0.41097692 |
| 84 | ATR | 0.39251319 |
| 85 | CSNK2A2 | 0.38979136 |
| 86 | PRKCA | 0.37969579 |
| 87 | AURKB | 0.36468267 |
| 88 | CSNK2A1 | 0.35488253 |
| 89 | CSNK1G3 | 0.34196364 |
| 90 | PRKACA | 0.34027488 |
| 91 | ROCK1 | 0.31771568 |
| 92 | CDC7 | 0.29762760 |
| 93 | PRKCD | 0.28856319 |
| 94 | MAPK15 | 0.28684554 |
| 95 | PAK1 | 0.28541110 |
| 96 | IGF1R | 0.28013749 |
| 97 | MAP2K7 | 0.26875313 |
| 98 | TAOK2 | 0.26270159 |
| 99 | MARK3 | 0.25143134 |
| 100 | FYN | 0.24583537 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.60651029 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.26508854 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.74232453 |
| 4 | Ribosome_Homo sapiens_hsa03010 | 3.43009109 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.23103231 |
| 6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.81498815 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.78188461 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.74219199 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.49009673 |
| 10 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.29397970 |
| 11 | Asthma_Homo sapiens_hsa05310 | 2.17645422 |
| 12 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.07059639 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 2.06769131 |
| 14 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.06523274 |
| 15 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.95250227 |
| 16 | RNA polymerase_Homo sapiens_hsa03020 | 1.92903427 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.92032581 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.91973376 |
| 19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.88708103 |
| 20 | Protein export_Homo sapiens_hsa03060 | 1.55326927 |
| 21 | Homologous recombination_Homo sapiens_hsa03440 | 1.53676049 |
| 22 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.52769200 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.47711719 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.39603086 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.39063308 |
| 26 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.38608774 |
| 27 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25574940 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.21745206 |
| 29 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.19265647 |
| 30 | DNA replication_Homo sapiens_hsa03030 | 1.18751069 |
| 31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.13273084 |
| 32 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.10806604 |
| 33 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.05901499 |
| 34 | Base excision repair_Homo sapiens_hsa03410 | 1.03862490 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 1.03569392 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 1.01248006 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.94105204 |
| 38 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.89501805 |
| 39 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.87453891 |
| 40 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.87318762 |
| 41 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.85456382 |
| 42 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.85008878 |
| 43 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.84769248 |
| 44 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.84543516 |
| 45 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.82908277 |
| 46 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.81589817 |
| 47 | Mismatch repair_Homo sapiens_hsa03430 | 0.81461496 |
| 48 | Purine metabolism_Homo sapiens_hsa00230 | 0.80744544 |
| 49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.74380313 |
| 50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.74302930 |
| 51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.73216901 |
| 52 | Measles_Homo sapiens_hsa05162 | 0.73090597 |
| 53 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.72110010 |
| 54 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.71371115 |
| 55 | RNA degradation_Homo sapiens_hsa03018 | 0.70263804 |
| 56 | Sulfur relay system_Homo sapiens_hsa04122 | 0.68942321 |
| 57 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.66103091 |
| 58 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.65972372 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.65317868 |
| 60 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.63406570 |
| 61 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62066026 |
| 62 | Spliceosome_Homo sapiens_hsa03040 | 0.62065451 |
| 63 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.61451626 |
| 64 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.60377948 |
| 65 | Retinol metabolism_Homo sapiens_hsa00830 | 0.60177550 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59496203 |
| 67 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58581744 |
| 68 | Malaria_Homo sapiens_hsa05144 | 0.58181853 |
| 69 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.57910263 |
| 70 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.57486322 |
| 71 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.55119052 |
| 72 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.53892263 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.53421950 |
| 74 | Salmonella infection_Homo sapiens_hsa05132 | 0.52289125 |
| 75 | Leishmaniasis_Homo sapiens_hsa05140 | 0.51469013 |
| 76 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.48561656 |
| 77 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.46538692 |
| 78 | Shigellosis_Homo sapiens_hsa05131 | 0.46101561 |
| 79 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.45738508 |
| 80 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.45719102 |
| 81 | Basal transcription factors_Homo sapiens_hsa03022 | 0.42391246 |
| 82 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.39733654 |
| 83 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.39410391 |
| 84 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.37627055 |
| 85 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.37198114 |
| 86 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.37115810 |
| 87 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.36361386 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35889796 |
| 89 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.34439487 |
| 90 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34403639 |
| 91 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.32809518 |
| 92 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.32777117 |
| 93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.32730695 |
| 94 | Alcoholism_Homo sapiens_hsa05034 | 0.28562906 |
| 95 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.26264319 |
| 96 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.22435095 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.17149350 |
| 98 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.15479218 |
| 99 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.14287143 |
| 100 | HTLV-I infection_Homo sapiens_hsa05166 | 0.14218517 |

