RPL35P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1maturation of SSU-rRNA (GO:0030490)8.62362439
2viral transcription (GO:0019083)7.39876257
3ribosomal small subunit biogenesis (GO:0042274)7.31997288
4translational termination (GO:0006415)7.09438397
5ribosomal small subunit assembly (GO:0000028)6.81407810
6energy coupled proton transport, down electrochemical gradient (GO:0015985)6.28282074
7ATP synthesis coupled proton transport (GO:0015986)6.28282074
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.13753657
9cotranslational protein targeting to membrane (GO:0006613)6.05737874
10protein targeting to ER (GO:0045047)6.03886878
11translational elongation (GO:0006414)5.93174132
12mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.85775792
13establishment of protein localization to endoplasmic reticulum (GO:0072599)5.75906218
14protein localization to endoplasmic reticulum (GO:0070972)5.69665368
15viral life cycle (GO:0019058)5.54081513
16chaperone-mediated protein transport (GO:0072321)5.52228868
17cellular protein complex disassembly (GO:0043624)5.35656472
18nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.13750914
19mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.94227496
20translational initiation (GO:0006413)4.71674527
21positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)4.57391304
22mitochondrial respiratory chain complex I assembly (GO:0032981)4.52695098
23NADH dehydrogenase complex assembly (GO:0010257)4.52695098
24mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.52695098
25protein complex disassembly (GO:0043241)4.52287433
26macromolecular complex disassembly (GO:0032984)4.46188231
27respiratory electron transport chain (GO:0022904)4.45112801
28electron transport chain (GO:0022900)4.38949922
29GTP biosynthetic process (GO:0006183)4.35874662
30organelle disassembly (GO:1903008)4.34932197
31protein complex biogenesis (GO:0070271)4.24967296
32regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)4.15372776
33purine nucleoside triphosphate biosynthetic process (GO:0009145)4.09361291
34ribosomal large subunit biogenesis (GO:0042273)4.08715750
35purine ribonucleoside triphosphate biosynthetic process (GO:0009206)4.06740288
36translation (GO:0006412)4.06724955
37protein targeting to membrane (GO:0006612)4.04335994
38protein neddylation (GO:0045116)4.01083718
39ATP biosynthetic process (GO:0006754)3.97539960
40UTP biosynthetic process (GO:0006228)3.94321936
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.93529217
42mitochondrial respiratory chain complex assembly (GO:0033108)3.83035801
43ribonucleoprotein complex biogenesis (GO:0022613)3.82348875
44nuclear-transcribed mRNA catabolic process (GO:0000956)3.69151137
45regulation of isotype switching to IgG isotypes (GO:0048302)3.67386685
46ribonucleoprotein complex disassembly (GO:0032988)3.66288679
47cellular component biogenesis (GO:0044085)3.66164228
48ribonucleoside triphosphate biosynthetic process (GO:0009201)3.63598496
49UTP metabolic process (GO:0046051)3.58929731
50mRNA catabolic process (GO:0006402)3.52300725
51tongue development (GO:0043586)3.50634720
52water-soluble vitamin biosynthetic process (GO:0042364)3.45588187
53DNA deamination (GO:0045006)3.39476753
54hydrogen ion transmembrane transport (GO:1902600)3.36073688
55somite development (GO:0061053)3.34175917
56kinetochore assembly (GO:0051382)3.26802692
57nucleoside triphosphate biosynthetic process (GO:0009142)3.25879791
58protein targeting to mitochondrion (GO:0006626)3.25149126
59pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)3.24231173
60substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.20608699
61substrate-independent telencephalic tangential migration (GO:0021826)3.20608699
62rRNA modification (GO:0000154)3.19532025
63tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.16825853
64RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.16825853
65behavioral response to nicotine (GO:0035095)3.16732352
66CTP biosynthetic process (GO:0006241)3.15253416
67CTP metabolic process (GO:0046036)3.15253416
68RNA catabolic process (GO:0006401)3.13484592
69preassembly of GPI anchor in ER membrane (GO:0016254)3.12535374
70rRNA processing (GO:0006364)3.11274550
71ovulation cycle (GO:0042698)3.06783812
72nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.06346384
73pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.04773849
74establishment of protein localization to mitochondrion (GO:0072655)3.03711471
75proton transport (GO:0015992)3.03427681
76nonmotile primary cilium assembly (GO:0035058)3.02923484
77rRNA metabolic process (GO:0016072)3.01987873
78exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.00370680
79hydrogen transport (GO:0006818)2.97477316
80cell proliferation in forebrain (GO:0021846)2.95387765
81protein localization to mitochondrion (GO:0070585)2.92862488
82pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.91944294
83protein targeting (GO:0006605)2.87560979
84homocysteine metabolic process (GO:0050667)2.84528966
85termination of RNA polymerase III transcription (GO:0006386)2.84220555
86transcription elongation from RNA polymerase III promoter (GO:0006385)2.84220555
87inner mitochondrial membrane organization (GO:0007007)2.81487520
88response to redox state (GO:0051775)2.79927247
89guanosine-containing compound biosynthetic process (GO:1901070)2.77444096
90establishment of protein localization to membrane (GO:0090150)2.76374776
91regulation of cilium movement (GO:0003352)2.73965970
92pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)2.71254125
93regulation of chronic inflammatory response (GO:0002676)2.69897074
94epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.69264846
95negative regulation of B cell apoptotic process (GO:0002903)2.66053081
96rRNA methylation (GO:0031167)2.66027045
97establishment of protein localization to organelle (GO:0072594)2.63479161
98ubiquinone biosynthetic process (GO:0006744)2.63175115
99kinetochore organization (GO:0051383)2.62441270
100regulation of immunoglobulin secretion (GO:0051023)2.60131482

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.85729384
2TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.14298608
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat4.13357270
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.85717603
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.46103163
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.40062176
7ETS1_20019798_ChIP-Seq_JURKAT_Human3.23051696
8EZH2_22144423_ChIP-Seq_EOC_Human3.18988869
9HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.05051122
10MYC_18555785_ChIP-Seq_MESCs_Mouse2.79782112
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65174577
12E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.54205471
13CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.51514511
14VDR_22108803_ChIP-Seq_LS180_Human2.40463153
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.35846953
16VDR_23849224_ChIP-Seq_CD4+_Human2.27137486
17CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.19649113
18ELK1_19687146_ChIP-ChIP_HELA_Human2.10668195
19CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.09833502
20CREB1_15753290_ChIP-ChIP_HEK293T_Human2.08449976
21IRF1_19129219_ChIP-ChIP_H3396_Human2.07735304
22HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.99229094
23FOXP3_21729870_ChIP-Seq_TREG_Human1.97627885
24SRF_21415370_ChIP-Seq_HL-1_Mouse1.94894831
25TTF2_22483619_ChIP-Seq_HELA_Human1.92322268
26MYC_18358816_ChIP-ChIP_MESCs_Mouse1.91805792
27MYC_18940864_ChIP-ChIP_HL60_Human1.87590966
28XRN2_22483619_ChIP-Seq_HELA_Human1.87560558
29ZNF274_21170338_ChIP-Seq_K562_Hela1.84856149
30GABP_19822575_ChIP-Seq_HepG2_Human1.81604600
31TP53_22573176_ChIP-Seq_HFKS_Human1.69001325
32CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.68842739
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.66558467
34MYC_19079543_ChIP-ChIP_MESCs_Mouse1.63309469
35EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.56164748
36PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.50204739
37POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.49080751
38MYC_19030024_ChIP-ChIP_MESCs_Mouse1.47140283
39E2F4_17652178_ChIP-ChIP_JURKAT_Human1.43028888
40NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.41054836
41CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.36011360
42POU5F1_16153702_ChIP-ChIP_HESCs_Human1.35613699
43TAF2_19829295_ChIP-Seq_ESCs_Human1.35284881
44FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.29790301
45SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.29756924
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.26896563
47MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.25275745
48ETV2_25802403_ChIP-Seq_MESCs_Mouse1.21139335
49SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.15937786
50EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.14438415
51GATA3_21878914_ChIP-Seq_MCF-7_Human1.13914195
52CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.13782745
53EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.13546556
54ELK1_22589737_ChIP-Seq_MCF10A_Human1.12889861
55E2F1_18555785_ChIP-Seq_MESCs_Mouse1.11490460
56NANOG_20526341_ChIP-Seq_ESCs_Human1.09306653
57CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.07519130
58FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.07468740
59ERA_21632823_ChIP-Seq_H3396_Human1.07358748
60TDRD3_21172665_ChIP-Seq_MCF-7_Human1.05466716
61TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.02209016
62DCP1A_22483619_ChIP-Seq_HELA_Human0.99918166
63GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.98469120
64STAT1_20625510_ChIP-Seq_HELA_Human0.97991642
65KDM5A_27292631_Chip-Seq_BREAST_Human0.97092898
66NCOR_22424771_ChIP-Seq_293T_Human0.97076230
67DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.96449613
68FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96258704
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.95936150
70EWS_26573619_Chip-Seq_HEK293_Human0.93542316
71REST_21632747_ChIP-Seq_MESCs_Mouse0.92513544
72BCL6_27268052_Chip-Seq_Bcells_Human0.92493575
73IGF1R_20145208_ChIP-Seq_DFB_Human0.92464986
74FLI1_27457419_Chip-Seq_LIVER_Mouse0.92162145
75RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91967003
76AR_20517297_ChIP-Seq_VCAP_Human0.91921903
77MYC_19829295_ChIP-Seq_ESCs_Human0.89989861
78FOXP1_21924763_ChIP-Seq_HESCs_Human0.89606056
79PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88954153
80ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.88758865
81PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.87032352
82CTCF_20526341_ChIP-Seq_ESCs_Human0.87007862
83AUTS2_25519132_ChIP-Seq_293T-REX_Human0.86277616
84ERG_20517297_ChIP-Seq_VCAP_Human0.85476581
85MYBL2_22936984_ChIP-ChIP_MESCs_Mouse0.84257566
86FOXA1_25329375_ChIP-Seq_VCAP_Human0.83873926
87FOXA1_27270436_Chip-Seq_PROSTATE_Human0.83873926
88FOXH1_21741376_ChIP-Seq_EPCs_Human0.83045982
89GATA6_21074721_ChIP-Seq_CACO-2_Human0.82488362
90CIITA_25753668_ChIP-Seq_RAJI_Human0.82290462
91SRY_22984422_ChIP-ChIP_TESTIS_Rat0.82110641
92CTCF_18555785_ChIP-Seq_MESCs_Mouse0.81652392
93EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.81638950
94SOX2_16153702_ChIP-ChIP_HESCs_Human0.80893755
95PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.80792283
96ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.80310376
97ELF1_20517297_ChIP-Seq_JURKAT_Human0.80226195
98FOXH1_21741376_ChIP-Seq_ESCs_Human0.79974077
99P53_21459846_ChIP-Seq_SAOS-2_Human0.78692025
100NOTCH1_21737748_ChIP-Seq_TLL_Human0.77913708

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation7.36330802
2MP0006292_abnormal_olfactory_placode4.52362472
3MP0004147_increased_porphyrin_level4.33842928
4MP0004142_abnormal_muscle_tone2.80585104
5MP0008877_abnormal_DNA_methylation2.76567580
6MP0003646_muscle_fatigue2.68735947
7MP0003122_maternal_imprinting2.53274867
8MP0005646_abnormal_pituitary_gland2.39438060
9MP0003787_abnormal_imprinting2.28215644
10MP0003880_abnormal_central_pattern2.21202985
11MP0008875_abnormal_xenobiotic_pharmacok2.17581677
12MP0005377_hearing/vestibular/ear_phenot1.99251658
13MP0003878_abnormal_ear_physiology1.99251658
14MP0001348_abnormal_lacrimal_gland1.93964936
15MP0004145_abnormal_muscle_electrophysio1.87767187
16MP0004885_abnormal_endolymph1.86605044
17MP0005083_abnormal_biliary_tract1.85321912
18MP0008789_abnormal_olfactory_epithelium1.84469520
19MP0002095_abnormal_skin_pigmentation1.69213132
20MP0005551_abnormal_eye_electrophysiolog1.60975112
21MP0001529_abnormal_vocalization1.60917761
22MP0002736_abnormal_nociception_after1.60912887
23MP0003186_abnormal_redox_activity1.60702775
24MP0003121_genomic_imprinting1.55007277
25MP0005499_abnormal_olfactory_system1.51975592
26MP0005394_taste/olfaction_phenotype1.51975592
27MP0001293_anophthalmia1.51502604
28MP0005423_abnormal_somatic_nervous1.44509055
29MP0006276_abnormal_autonomic_nervous1.43835442
30MP0008872_abnormal_physiological_respon1.39848336
31MP0001873_stomach_inflammation1.39474268
32MP0002160_abnormal_reproductive_system1.38461111
33MP0005389_reproductive_system_phenotype1.36755633
34MP0005671_abnormal_response_to1.36584281
35MP0001968_abnormal_touch/_nociception1.36130471
36MP0006036_abnormal_mitochondrial_physio1.35762481
37MP0002653_abnormal_ependyma_morphology1.32601238
38MP0001905_abnormal_dopamine_level1.31420139
39MP0002163_abnormal_gland_morphology1.31040299
40MP0003806_abnormal_nucleotide_metabolis1.29347366
41MP0003879_abnormal_hair_cell1.27905025
42MP0004742_abnormal_vestibular_system1.25183061
43MP0006072_abnormal_retinal_apoptosis1.23590069
44MP0001919_abnormal_reproductive_system1.21522523
45MP0001986_abnormal_taste_sensitivity1.15588038
46MP0001835_abnormal_antigen_presentation1.13405467
47MP0000631_abnormal_neuroendocrine_gland1.12845711
48MP0002938_white_spotting1.12284679
49MP0001440_abnormal_grooming_behavior1.10557504
50MP0003011_delayed_dark_adaptation1.05985320
51MP0009764_decreased_sensitivity_to1.05474240
52MP0005360_urolithiasis1.04390961
53MP0002272_abnormal_nervous_system1.04009073
54MP0000685_abnormal_immune_system1.03858579
55MP0000778_abnormal_nervous_system0.99016788
56MP0002557_abnormal_social/conspecific_i0.95720136
57MP0002752_abnormal_somatic_nervous0.94257154
58MP0000427_abnormal_hair_cycle0.94138009
59MP0005195_abnormal_posterior_eye0.90765271
60MP0002102_abnormal_ear_morphology0.90494374
61MP0003718_maternal_effect0.90014338
62MP0000955_abnormal_spinal_cord0.89894858
63MP0006035_abnormal_mitochondrial_morpho0.89522852
64MP0001970_abnormal_pain_threshold0.88017933
65MP0005410_abnormal_fertilization0.87411612
66MP0003123_paternal_imprinting0.85673797
67MP0008058_abnormal_DNA_repair0.83578431
68MP0002184_abnormal_innervation0.83055272
69MP0003136_yellow_coat_color0.83028302
70MP0002067_abnormal_sensory_capabilities0.82742405
71MP0002876_abnormal_thyroid_physiology0.81799049
72MP0002277_abnormal_respiratory_mucosa0.81162491
73MP0002210_abnormal_sex_determination0.80347879
74MP0002138_abnormal_hepatobiliary_system0.78406933
75MP0000049_abnormal_middle_ear0.77865189
76MP0009745_abnormal_behavioral_response0.77490524
77MP0002733_abnormal_thermal_nociception0.76508132
78MP0001764_abnormal_homeostasis0.76274247
79MP0003315_abnormal_perineum_morphology0.74366442
80MP0002572_abnormal_emotion/affect_behav0.74283913
81MP0005645_abnormal_hypothalamus_physiol0.74037376
82MP0001485_abnormal_pinna_reflex0.73777832
83MP0001324_abnormal_eye_pigmentation0.73191471
84MP0002822_catalepsy0.72323610
85MP0000026_abnormal_inner_ear0.71549928
86MP0000015_abnormal_ear_pigmentation0.71002828
87MP0009046_muscle_twitch0.69364630
88MP0005084_abnormal_gallbladder_morpholo0.69255916
89MP0005636_abnormal_mineral_homeostasis0.65584972
90MP0001984_abnormal_olfaction0.64610628
91MP0009053_abnormal_anal_canal0.63952795
92MP0003942_abnormal_urinary_system0.63891119
93MP0002882_abnormal_neuron_morphology0.62988369
94MP0005253_abnormal_eye_physiology0.62866774
95MP0001286_abnormal_eye_development0.61737893
96MP0005310_abnormal_salivary_gland0.59387891
97MP0005448_abnormal_energy_balance0.56697755
98MP0005332_abnormal_amino_acid0.56687127
99MP0005379_endocrine/exocrine_gland_phen0.56295424
100MP0002064_seizures0.55153634

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)6.34272034
2Abnormal mitochondria in muscle tissue (HP:0008316)5.80086273
3Acute encephalopathy (HP:0006846)5.48519879
4Reticulocytopenia (HP:0001896)5.29758300
5Progressive macrocephaly (HP:0004481)5.05845494
6Mitochondrial inheritance (HP:0001427)4.81965264
7Increased CSF lactate (HP:0002490)4.32702776
8Hepatocellular necrosis (HP:0001404)4.24262911
9Molar tooth sign on MRI (HP:0002419)4.04585728
10Abnormality of midbrain morphology (HP:0002418)4.04585728
11Abnormality of cells of the erythroid lineage (HP:0012130)3.98334564
12Cerebral edema (HP:0002181)3.83452091
13Pancreatic fibrosis (HP:0100732)3.63456723
14Pancreatic cysts (HP:0001737)3.49803624
15Hepatic necrosis (HP:0002605)3.47923237
16Pallor (HP:0000980)3.31319340
17Abnormal hemoglobin (HP:0011902)3.30100212
18Optic disc pallor (HP:0000543)3.27740701
19Abnormal number of erythroid precursors (HP:0012131)3.27537174
203-Methylglutaconic aciduria (HP:0003535)3.26127042
21True hermaphroditism (HP:0010459)3.07267924
22Nephronophthisis (HP:0000090)3.05140492
23Lipid accumulation in hepatocytes (HP:0006561)3.00480235
24Leukodystrophy (HP:0002415)2.96880591
25Decreased activity of mitochondrial respiratory chain (HP:0008972)2.95895284
26Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.95895284
27Increased hepatocellular lipid droplets (HP:0006565)2.95045877
28Macrocytic anemia (HP:0001972)2.91957703
29Absent rod-and cone-mediated responses on ERG (HP:0007688)2.85431561
30Anencephaly (HP:0002323)2.73535280
31Abnormality of the heme biosynthetic pathway (HP:0010472)2.72226977
32Increased intramyocellular lipid droplets (HP:0012240)2.67048344
33Increased serum lactate (HP:0002151)2.65513622
34Respiratory failure (HP:0002878)2.61338823
35Aplasia/Hypoplasia of the sacrum (HP:0008517)2.61176643
36Abnormality of DNA repair (HP:0003254)2.59036606
37Exercise intolerance (HP:0003546)2.58196880
38Renal Fanconi syndrome (HP:0001994)2.56959676
39Lactic acidosis (HP:0003128)2.51904321
40Absent thumb (HP:0009777)2.44320093
41Pendular nystagmus (HP:0012043)2.42757259
42Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.40714690
43Increased muscle lipid content (HP:0009058)2.39522612
44Medial flaring of the eyebrow (HP:0010747)2.33089207
45Cystic liver disease (HP:0006706)2.31856275
46Abnormality of the renal medulla (HP:0100957)2.26231259
47Sclerocornea (HP:0000647)2.25930786
48Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.23272890
49Horseshoe kidney (HP:0000085)2.19179832
50Exertional dyspnea (HP:0002875)2.19155549
51Septo-optic dysplasia (HP:0100842)2.18163657
52Rib fusion (HP:0000902)2.17857273
53X-linked dominant inheritance (HP:0001423)2.14461333
54Abnormal rod and cone electroretinograms (HP:0008323)2.09461907
55Chronic hepatic failure (HP:0100626)2.03804269
56Abnormality of the renal collecting system (HP:0004742)2.03012697
57Congenital hepatic fibrosis (HP:0002612)2.01660225
58Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.97773236
59Lethargy (HP:0001254)1.96838166
60Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.94401992
61Hyperthyroidism (HP:0000836)1.93767495
62Porencephaly (HP:0002132)1.93408136
63Chronic bronchitis (HP:0004469)1.92954556
64Type II lissencephaly (HP:0007260)1.92463042
65Duplicated collecting system (HP:0000081)1.89767076
66Depressed nasal ridge (HP:0000457)1.87910219
67Abnormality of reticulocytes (HP:0004312)1.87386672
68Microretrognathia (HP:0000308)1.83433821
69Bifid tongue (HP:0010297)1.82898432
70Postaxial foot polydactyly (HP:0001830)1.79671139
71Cleft eyelid (HP:0000625)1.78656383
72Median cleft lip (HP:0000161)1.78169173
73Anophthalmia (HP:0000528)1.75330957
74Aplasia/Hypoplasia of the spleen (HP:0010451)1.73093104
75Abolished electroretinogram (ERG) (HP:0000550)1.72927080
76Type 2 muscle fiber atrophy (HP:0003554)1.71371335
77Abnormal respiratory motile cilium physiology (HP:0012261)1.69586756
78Aplasia/Hypoplasia of the tongue (HP:0010295)1.68693648
79Holoprosencephaly (HP:0001360)1.68507304
80Abnormality of renal resorption (HP:0011038)1.66988833
81Gait imbalance (HP:0002141)1.66266610
82Hypoplasia of the ulna (HP:0003022)1.65619219
83Blindness (HP:0000618)1.65251540
84Absent septum pellucidum (HP:0001331)1.65126008
85Congenital ichthyosiform erythroderma (HP:0007431)1.64891152
86Ectopic kidney (HP:0000086)1.64562480
87Myokymia (HP:0002411)1.62751183
88Cerebellar dysplasia (HP:0007033)1.62451784
89Dynein arm defect of respiratory motile cilia (HP:0012255)1.62378575
90Absent/shortened dynein arms (HP:0200106)1.62378575
91Tubular atrophy (HP:0000092)1.62225657
92Lissencephaly (HP:0001339)1.58964712
93Aplasia/Hypoplasia of the tibia (HP:0005772)1.58565352
94Aplasia/Hypoplasia of the uvula (HP:0010293)1.58083256
95Abnormality of the phalanges of the 5th finger (HP:0004213)1.57612131
96Severe muscular hypotonia (HP:0006829)1.57226724
97Hyperglycinemia (HP:0002154)1.57013671
98Chromosomal breakage induced by crosslinking agents (HP:0003221)1.56841953
99Paralysis (HP:0003470)1.56772613
100Chromsome breakage (HP:0040012)1.56625621

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK163.24627355
2TLK13.20394843
3EPHB22.92449236
4EIF2AK12.75355164
5ZAK2.40401943
6NUAK12.35712061
7WNK42.28957697
8NME22.21338974
9PIK3CA2.11826641
10TAOK32.08023846
11GRK12.04814620
12DYRK21.82236593
13BMPR21.72379118
14NME11.61592894
15BCKDK1.61505096
16CAMK1D1.47337262
17PAK31.40970200
18ADRBK21.38151276
19LRRK21.32390171
20VRK21.29401013
21TXK1.29115157
22CAMK1G1.27627314
23FRK1.25015850
24MAPK131.23037004
25CASK1.17194383
26CDK191.16434952
27PIM21.15118704
28PRKCG1.14351456
29ARAF1.09823199
30TNIK1.08811157
31PINK11.06539626
32PKN11.04968259
33VRK11.03653424
34PRKCQ1.03131602
35TEC1.02374730
36PRKCH1.01476938
37MAP2K60.99883768
38AURKB0.99434429
39TRIM280.96618891
40DAPK30.94803346
41ADRBK10.94476028
42ILK0.90786016
43CAMK10.90118022
44TIE10.90054211
45IKBKB0.90027780
46ERBB40.88065800
47CSNK2A20.87688104
48AURKA0.87240497
49CAMKK20.87143391
50RPS6KA60.86205791
51STK40.85747845
52NTRK20.85055535
53BMPR1B0.84084982
54PRKCI0.83764912
55PLK20.82975093
56PHKG20.81463524
57PHKG10.81463524
58RPS6KA50.81060012
59NEK10.80822517
60DMPK0.79390796
61STK110.78519683
62PLK30.76048548
63MAPKAPK30.75257080
64RPS6KL10.73820472
65RPS6KC10.73820472
66MAP3K40.73074561
67CHEK20.72757777
68PNCK0.72445743
69EPHA40.71572447
70ERBB20.70062198
71CSNK2A10.68020452
72PLK10.67354805
73ABL20.66537359
74STK240.65099645
75EIF2AK20.64647124
76INSRR0.64010478
77STK30.63994756
78PIM10.63224952
79WNK30.61391884
80CSNK1E0.59667551
81PRKACA0.57746899
82OXSR10.57669612
83RPS6KB10.56044207
84ATR0.55547530
85PDK20.55460387
86MAP4K10.55447987
87WNK10.54194051
88ITK0.52848188
89MAP3K90.48549206
90SRPK10.48267587
91BTK0.47949450
92PRKDC0.44888512
93CAMK2G0.44463323
94MARK20.44336323
95PRKCZ0.43881422
96CAMK2A0.42933048
97TYRO30.41037019
98STK390.40570087
99OBSCN0.40532944
100RPS6KA10.40003010

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.92088426
2Oxidative phosphorylation_Homo sapiens_hsa001904.61608565
3Parkinsons disease_Homo sapiens_hsa050123.79215807
4Asthma_Homo sapiens_hsa053103.16723227
5Huntingtons disease_Homo sapiens_hsa050162.92103124
6Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.71391696
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.60240884
8Protein export_Homo sapiens_hsa030602.56714460
9Alzheimers disease_Homo sapiens_hsa050102.54927978
10RNA polymerase_Homo sapiens_hsa030202.53308327
11Proteasome_Homo sapiens_hsa030502.48168355
12Cardiac muscle contraction_Homo sapiens_hsa042602.40138831
13Intestinal immune network for IgA production_Homo sapiens_hsa046722.06024011
14Sulfur relay system_Homo sapiens_hsa041221.97066947
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.95446847
16Allograft rejection_Homo sapiens_hsa053301.81983762
17Autoimmune thyroid disease_Homo sapiens_hsa053201.75853340
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.61228038
19Graft-versus-host disease_Homo sapiens_hsa053321.59574380
20Nucleotide excision repair_Homo sapiens_hsa034201.55482781
21One carbon pool by folate_Homo sapiens_hsa006701.47379965
22Mismatch repair_Homo sapiens_hsa034301.44001657
23Basal transcription factors_Homo sapiens_hsa030221.41553166
24Nitrogen metabolism_Homo sapiens_hsa009101.36824680
25RNA degradation_Homo sapiens_hsa030181.31157102
26Pyrimidine metabolism_Homo sapiens_hsa002401.29338291
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.28306917
28Primary bile acid biosynthesis_Homo sapiens_hsa001201.26631857
29Fanconi anemia pathway_Homo sapiens_hsa034601.25390654
30Homologous recombination_Homo sapiens_hsa034401.22539606
31Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.22410619
32Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.18629708
33Type I diabetes mellitus_Homo sapiens_hsa049401.16154863
34Linoleic acid metabolism_Homo sapiens_hsa005911.13924709
35alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.08724886
36DNA replication_Homo sapiens_hsa030301.08214184
37Collecting duct acid secretion_Homo sapiens_hsa049661.03180070
38Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.98822717
39Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.96929836
40Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.94274429
41Cysteine and methionine metabolism_Homo sapiens_hsa002700.93041217
42Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.88834205
43Steroid biosynthesis_Homo sapiens_hsa001000.88619721
44Phototransduction_Homo sapiens_hsa047440.87902871
45Peroxisome_Homo sapiens_hsa041460.85940809
46Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.83446473
47Folate biosynthesis_Homo sapiens_hsa007900.81951165
48Base excision repair_Homo sapiens_hsa034100.78026523
49Nicotine addiction_Homo sapiens_hsa050330.77773058
50Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.77632007
51Propanoate metabolism_Homo sapiens_hsa006400.75935596
52Fat digestion and absorption_Homo sapiens_hsa049750.74610883
53Metabolic pathways_Homo sapiens_hsa011000.70792237
54Systemic lupus erythematosus_Homo sapiens_hsa053220.70118998
55Mineral absorption_Homo sapiens_hsa049780.66307968
56Tryptophan metabolism_Homo sapiens_hsa003800.62217019
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61224225
58Butanoate metabolism_Homo sapiens_hsa006500.60218162
59Rheumatoid arthritis_Homo sapiens_hsa053230.59938538
60Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59724109
61Pyruvate metabolism_Homo sapiens_hsa006200.58890957
62Purine metabolism_Homo sapiens_hsa002300.58496588
63Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.54802894
64Hematopoietic cell lineage_Homo sapiens_hsa046400.54756498
65Chemical carcinogenesis_Homo sapiens_hsa052040.54137638
66Olfactory transduction_Homo sapiens_hsa047400.53370164
67Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.52317636
68Spliceosome_Homo sapiens_hsa030400.51501053
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.50305708
70Vitamin B6 metabolism_Homo sapiens_hsa007500.48661911
71RNA transport_Homo sapiens_hsa030130.47625540
72Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.46811807
73Dorso-ventral axis formation_Homo sapiens_hsa043200.45897713
74Ether lipid metabolism_Homo sapiens_hsa005650.45733007
75Antigen processing and presentation_Homo sapiens_hsa046120.44742240
76Morphine addiction_Homo sapiens_hsa050320.41608058
77Arachidonic acid metabolism_Homo sapiens_hsa005900.40913502
78Glycerolipid metabolism_Homo sapiens_hsa005610.40171113
79Retinol metabolism_Homo sapiens_hsa008300.35674740
80Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.33263921
81Jak-STAT signaling pathway_Homo sapiens_hsa046300.32946955
82Fatty acid degradation_Homo sapiens_hsa000710.31254624
83Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26881713
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.26862241
85Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.26773378
86Alcoholism_Homo sapiens_hsa050340.25321018
87SNARE interactions in vesicular transport_Homo sapiens_hsa041300.25066364
88Pentose and glucuronate interconversions_Homo sapiens_hsa000400.23791237
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.23267072
90Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.22610748
91Sulfur metabolism_Homo sapiens_hsa009200.20233899
92Epstein-Barr virus infection_Homo sapiens_hsa051690.18343468
93GABAergic synapse_Homo sapiens_hsa047270.16860121
94beta-Alanine metabolism_Homo sapiens_hsa004100.16826186
95Primary immunodeficiency_Homo sapiens_hsa053400.15226781
96Regulation of autophagy_Homo sapiens_hsa041400.14710364
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.11407155
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.10973296
99Taste transduction_Homo sapiens_hsa047420.10658195
100Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.10538396

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »