Rank | Gene Set | Z-score |
---|---|---|
1 | cytidine catabolic process (GO:0006216) | 7.86381225 |
2 | cytidine deamination (GO:0009972) | 7.86381225 |
3 | cytidine metabolic process (GO:0046087) | 7.86381225 |
4 | DNA deamination (GO:0045006) | 7.17749222 |
5 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.98530520 |
6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 6.84039591 |
7 | ribosomal small subunit assembly (GO:0000028) | 5.40123009 |
8 | response to gravity (GO:0009629) | 5.03289630 |
9 | viral transcription (GO:0019083) | 4.57931414 |
10 | ATP synthesis coupled proton transport (GO:0015986) | 4.45301692 |
11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.45301692 |
12 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.44104709 |
13 | translational termination (GO:0006415) | 4.35712598 |
14 | ribosomal small subunit biogenesis (GO:0042274) | 4.30325220 |
15 | protein complex biogenesis (GO:0070271) | 4.18693831 |
16 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.10794751 |
17 | translational elongation (GO:0006414) | 4.04524187 |
18 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.97971537 |
19 | skeletal muscle adaptation (GO:0043501) | 3.97546107 |
20 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.94315645 |
21 | striated muscle atrophy (GO:0014891) | 3.93645129 |
22 | skeletal muscle tissue regeneration (GO:0043403) | 3.88792086 |
23 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.83521012 |
24 | protein targeting to ER (GO:0045047) | 3.81754869 |
25 | respiratory electron transport chain (GO:0022904) | 3.79394684 |
26 | cotranslational protein targeting to membrane (GO:0006613) | 3.77882534 |
27 | negative regulation of muscle hypertrophy (GO:0014741) | 3.76415465 |
28 | actin-myosin filament sliding (GO:0033275) | 3.74071312 |
29 | muscle filament sliding (GO:0030049) | 3.74071312 |
30 | electron transport chain (GO:0022900) | 3.73932563 |
31 | muscle atrophy (GO:0014889) | 3.73440080 |
32 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.69846697 |
33 | chaperone-mediated protein transport (GO:0072321) | 3.68277264 |
34 | sequestering of actin monomers (GO:0042989) | 3.66996715 |
35 | maturation of SSU-rRNA (GO:0030490) | 3.65799426 |
36 | regulation of skeletal muscle contraction (GO:0014819) | 3.65191299 |
37 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.61456769 |
38 | protein localization to endoplasmic reticulum (GO:0070972) | 3.60759729 |
39 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.60575078 |
40 | behavioral response to nicotine (GO:0035095) | 3.59703299 |
41 | protein neddylation (GO:0045116) | 3.50881271 |
42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.47613140 |
43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.47613140 |
44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.47613140 |
45 | positive regulation of T cell apoptotic process (GO:0070234) | 3.47008444 |
46 | positive regulation of translational initiation (GO:0045948) | 3.31109464 |
47 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.27778973 |
48 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.27415242 |
49 | viral life cycle (GO:0019058) | 3.22278905 |
50 | cellular protein complex disassembly (GO:0043624) | 3.21055031 |
51 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.18971457 |
52 | protein polyglutamylation (GO:0018095) | 3.15233699 |
53 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.13753436 |
54 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.11655701 |
55 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.11655701 |
56 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.10197208 |
57 | cytolysis (GO:0019835) | 3.06832065 |
58 | negative regulation by host of viral transcription (GO:0043922) | 3.05815879 |
59 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.05044432 |
60 | positive regulation of B cell differentiation (GO:0045579) | 3.02193114 |
61 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.01509843 |
62 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.01358386 |
63 | translation (GO:0006412) | 2.99872722 |
64 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.97181873 |
65 | positive T cell selection (GO:0043368) | 2.96987528 |
66 | regulation of chronic inflammatory response (GO:0002676) | 2.96315149 |
67 | regulation of activation of Janus kinase activity (GO:0010533) | 2.94977090 |
68 | cytochrome complex assembly (GO:0017004) | 2.93397659 |
69 | DNA demethylation (GO:0080111) | 2.92832317 |
70 | translational initiation (GO:0006413) | 2.92002801 |
71 | pseudouridine synthesis (GO:0001522) | 2.89457071 |
72 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 2.87285133 |
73 | ubiquinone biosynthetic process (GO:0006744) | 2.86788124 |
74 | platelet dense granule organization (GO:0060155) | 2.85617550 |
75 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.85298518 |
76 | actin-mediated cell contraction (GO:0070252) | 2.84649761 |
77 | positive thymic T cell selection (GO:0045059) | 2.83532951 |
78 | actin nucleation (GO:0045010) | 2.83171079 |
79 | response to muscle activity (GO:0014850) | 2.83046712 |
80 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.81709798 |
81 | negative regulation of organelle assembly (GO:1902116) | 2.77667932 |
82 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.76233833 |
83 | T cell migration (GO:0072678) | 2.73173782 |
84 | cellular component biogenesis (GO:0044085) | 2.70209069 |
85 | hydrogen ion transmembrane transport (GO:1902600) | 2.68160170 |
86 | regulation of calcium-mediated signaling (GO:0050848) | 2.67101139 |
87 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.65015142 |
88 | regulation of B cell differentiation (GO:0045577) | 2.64941807 |
89 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.64552823 |
90 | negative T cell selection (GO:0043383) | 2.63476664 |
91 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.63075231 |
92 | eosinophil chemotaxis (GO:0048245) | 2.62436159 |
93 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.62157453 |
94 | negative regulation of viral genome replication (GO:0045071) | 2.61478034 |
95 | positive regulation of defense response to virus by host (GO:0002230) | 2.61215697 |
96 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.60799183 |
97 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.60799183 |
98 | ATP biosynthetic process (GO:0006754) | 2.60795509 |
99 | rRNA modification (GO:0000154) | 2.60350097 |
100 | positive regulation of cell killing (GO:0031343) | 2.60253725 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.82104099 |
2 | VDR_22108803_ChIP-Seq_LS180_Human | 4.66193094 |
3 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.45747698 |
4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.13044292 |
5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.10130953 |
6 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.96408097 |
7 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.93774769 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.74638260 |
9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.71060276 |
10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.68358322 |
11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.66856357 |
12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.30189790 |
13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.28468744 |
14 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.07306995 |
15 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.03661236 |
16 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.96104785 |
17 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.95256171 |
18 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.95131212 |
19 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.88009047 |
20 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.75861070 |
21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.74753749 |
22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.72178159 |
23 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.64773887 |
24 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.64159495 |
25 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.61474248 |
26 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.59113587 |
27 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.56671007 |
28 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.54140831 |
29 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47838714 |
30 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.43582101 |
31 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.42952417 |
32 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.39679089 |
33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.38120873 |
34 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.35602383 |
35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.35003179 |
36 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.34161727 |
37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.32096577 |
38 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30527530 |
39 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.30507912 |
40 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.30494978 |
41 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29014218 |
42 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.26650061 |
43 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.25285309 |
44 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.25080725 |
45 | NCOR_22424771_ChIP-Seq_293T_Human | 1.24065651 |
46 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.23661084 |
47 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.21644324 |
48 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.21022603 |
49 | AR_20517297_ChIP-Seq_VCAP_Human | 1.20436471 |
50 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.19839046 |
51 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.19460010 |
52 | MYB_26560356_Chip-Seq_TH2_Human | 1.18700987 |
53 | ERA_21632823_ChIP-Seq_H3396_Human | 1.18457242 |
54 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18029765 |
55 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.17980248 |
56 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.17508305 |
57 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.16530349 |
58 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.16081152 |
59 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.15382534 |
60 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.13511061 |
61 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.11878423 |
62 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11760343 |
63 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.10973276 |
64 | GATA3_26560356_Chip-Seq_TH2_Human | 1.10679517 |
65 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.07224772 |
66 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06251076 |
67 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.03460387 |
68 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.03446318 |
69 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.03387972 |
70 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.02180505 |
71 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.02113947 |
72 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.01264015 |
73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01113717 |
74 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.00243285 |
75 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.99859688 |
76 | FUS_26573619_Chip-Seq_HEK293_Human | 0.99623692 |
77 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.97422397 |
78 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97264157 |
79 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.96121836 |
80 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.94771783 |
81 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.94367236 |
82 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.94333541 |
83 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.94333541 |
84 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.94132089 |
85 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.93440167 |
86 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92820921 |
87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.92468567 |
88 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91753649 |
89 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.91287080 |
90 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.91003791 |
91 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.90555369 |
92 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.90555369 |
93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89310223 |
94 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.88445137 |
95 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.88338381 |
96 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.88085482 |
97 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.87979015 |
98 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.87853740 |
99 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.84520997 |
100 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.83433296 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005671_abnormal_response_to | 4.34813100 |
2 | MP0006292_abnormal_olfactory_placode | 4.15434090 |
3 | MP0004145_abnormal_muscle_electrophysio | 3.59421849 |
4 | MP0002638_abnormal_pupillary_reflex | 3.50569895 |
5 | MP0009379_abnormal_foot_pigmentation | 3.44780337 |
6 | MP0003646_muscle_fatigue | 3.41584980 |
7 | MP0004147_increased_porphyrin_level | 2.74888497 |
8 | MP0002138_abnormal_hepatobiliary_system | 2.24363471 |
9 | MP0000372_irregular_coat_pigmentation | 2.16951105 |
10 | MP0005645_abnormal_hypothalamus_physiol | 1.84837068 |
11 | MP0009333_abnormal_splenocyte_physiolog | 1.84361465 |
12 | MP0008877_abnormal_DNA_methylation | 1.81423470 |
13 | MP0009785_altered_susceptibility_to | 1.79303577 |
14 | MP0005083_abnormal_biliary_tract | 1.79034583 |
15 | MP0003787_abnormal_imprinting | 1.74361764 |
16 | MP0001835_abnormal_antigen_presentation | 1.72226339 |
17 | MP0002837_dystrophic_cardiac_calcinosis | 1.67990300 |
18 | MP0008789_abnormal_olfactory_epithelium | 1.67325960 |
19 | MP0001968_abnormal_touch/_nociception | 1.66416872 |
20 | MP0001905_abnormal_dopamine_level | 1.66362646 |
21 | MP0006072_abnormal_retinal_apoptosis | 1.66261285 |
22 | MP0002102_abnormal_ear_morphology | 1.64567566 |
23 | MP0002095_abnormal_skin_pigmentation | 1.60868951 |
24 | MP0002736_abnormal_nociception_after | 1.55763864 |
25 | MP0003763_abnormal_thymus_physiology | 1.55173691 |
26 | MP0002277_abnormal_respiratory_mucosa | 1.52493139 |
27 | MP0005551_abnormal_eye_electrophysiolog | 1.51212717 |
28 | MP0002876_abnormal_thyroid_physiology | 1.43681308 |
29 | MP0004142_abnormal_muscle_tone | 1.42123182 |
30 | MP0001800_abnormal_humoral_immune | 1.39560391 |
31 | MP0000747_muscle_weakness | 1.39029233 |
32 | MP0005084_abnormal_gallbladder_morpholo | 1.38043737 |
33 | MP0003786_premature_aging | 1.36766495 |
34 | MP0001919_abnormal_reproductive_system | 1.34453106 |
35 | MP0008872_abnormal_physiological_respon | 1.34143696 |
36 | MP0002089_abnormal_postnatal_growth/wei | 1.33584934 |
37 | MP0000685_abnormal_immune_system | 1.29711143 |
38 | MP0008995_early_reproductive_senescence | 1.29503503 |
39 | MP0005000_abnormal_immune_tolerance | 1.28891404 |
40 | MP0005389_reproductive_system_phenotype | 1.27930512 |
41 | MP0003878_abnormal_ear_physiology | 1.26650888 |
42 | MP0005377_hearing/vestibular/ear_phenot | 1.26650888 |
43 | MP0005387_immune_system_phenotype | 1.26598323 |
44 | MP0001790_abnormal_immune_system | 1.26598323 |
45 | MP0004036_abnormal_muscle_relaxation | 1.25302833 |
46 | MP0002723_abnormal_immune_serum | 1.25255526 |
47 | MP0002148_abnormal_hypersensitivity_rea | 1.24853846 |
48 | MP0003880_abnormal_central_pattern | 1.22827495 |
49 | MP0000749_muscle_degeneration | 1.21658866 |
50 | MP0004885_abnormal_endolymph | 1.21436524 |
51 | MP0002420_abnormal_adaptive_immunity | 1.18684170 |
52 | MP0001485_abnormal_pinna_reflex | 1.14692372 |
53 | MP0001819_abnormal_immune_cell | 1.13220988 |
54 | MP0002160_abnormal_reproductive_system | 1.12494506 |
55 | MP0002938_white_spotting | 1.08746236 |
56 | MP0001661_extended_life_span | 1.07871850 |
57 | MP0005025_abnormal_response_to | 1.05148456 |
58 | MP0002163_abnormal_gland_morphology | 1.04458160 |
59 | MP0003959_abnormal_lean_body | 1.03962221 |
60 | MP0001873_stomach_inflammation | 1.02754507 |
61 | MP0003866_abnormal_defecation | 1.01262336 |
62 | MP0005423_abnormal_somatic_nervous | 0.99611256 |
63 | MP0009745_abnormal_behavioral_response | 0.97692037 |
64 | MP0002106_abnormal_muscle_physiology | 0.97165967 |
65 | MP0005620_abnormal_muscle_contractility | 0.96523520 |
66 | MP0006276_abnormal_autonomic_nervous | 0.94153623 |
67 | MP0000631_abnormal_neuroendocrine_gland | 0.93784091 |
68 | MP0002272_abnormal_nervous_system | 0.93560458 |
69 | MP0005499_abnormal_olfactory_system | 0.93427250 |
70 | MP0005394_taste/olfaction_phenotype | 0.93427250 |
71 | MP0002733_abnormal_thermal_nociception | 0.92951068 |
72 | MP0004130_abnormal_muscle_cell | 0.90954817 |
73 | MP0008875_abnormal_xenobiotic_pharmacok | 0.90642129 |
74 | MP0000716_abnormal_immune_system | 0.90412644 |
75 | MP0002269_muscular_atrophy | 0.89033607 |
76 | MP0002108_abnormal_muscle_morphology | 0.88343522 |
77 | MP0000049_abnormal_middle_ear | 0.87303870 |
78 | MP0005410_abnormal_fertilization | 0.86567187 |
79 | MP0005646_abnormal_pituitary_gland | 0.84723237 |
80 | MP0002398_abnormal_bone_marrow | 0.84071627 |
81 | MP0005253_abnormal_eye_physiology | 0.83852288 |
82 | MP0005636_abnormal_mineral_homeostasis | 0.83188488 |
83 | MP0000759_abnormal_skeletal_muscle | 0.82819920 |
84 | MP0001293_anophthalmia | 0.82653567 |
85 | MP0002452_abnormal_antigen_presenting | 0.81757818 |
86 | MP0004742_abnormal_vestibular_system | 0.81712451 |
87 | MP0001970_abnormal_pain_threshold | 0.78877951 |
88 | MP0001486_abnormal_startle_reflex | 0.77339696 |
89 | MP0005379_endocrine/exocrine_gland_phen | 0.75318771 |
90 | MP0000703_abnormal_thymus_morphology | 0.73564412 |
91 | MP0005369_muscle_phenotype | 0.73311722 |
92 | MP0001119_abnormal_female_reproductive | 0.72136961 |
93 | MP0003806_abnormal_nucleotide_metabolis | 0.71960216 |
94 | MP0001765_abnormal_ion_homeostasis | 0.71676457 |
95 | MP0003252_abnormal_bile_duct | 0.70536185 |
96 | MP0002006_tumorigenesis | 0.70448616 |
97 | MP0002653_abnormal_ependyma_morphology | 0.70279449 |
98 | MP0002166_altered_tumor_susceptibility | 0.70135743 |
99 | MP0001986_abnormal_taste_sensitivity | 0.68967175 |
100 | MP0005195_abnormal_posterior_eye | 0.66828096 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Palpebral edema (HP:0100540) | 4.75020462 |
2 | Aplastic anemia (HP:0001915) | 4.36013074 |
3 | Acute necrotizing encephalopathy (HP:0006965) | 4.25081750 |
4 | Congenital stationary night blindness (HP:0007642) | 4.06705991 |
5 | Mitochondrial inheritance (HP:0001427) | 3.99578714 |
6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.84965873 |
7 | Increased CSF lactate (HP:0002490) | 3.51713114 |
8 | Acute encephalopathy (HP:0006846) | 3.51632258 |
9 | Progressive macrocephaly (HP:0004481) | 3.46114010 |
10 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.39718401 |
11 | Increased hepatocellular lipid droplets (HP:0006565) | 3.31449979 |
12 | IgG deficiency (HP:0004315) | 3.27473888 |
13 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.18438293 |
14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.09749351 |
15 | Hepatocellular necrosis (HP:0001404) | 3.08155738 |
16 | Absent phalangeal crease (HP:0006109) | 3.03487534 |
17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.02644776 |
18 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.90295780 |
19 | Distal arthrogryposis (HP:0005684) | 2.88285556 |
20 | 3-Methylglutaconic aciduria (HP:0003535) | 2.87589055 |
21 | Abnormality of midbrain morphology (HP:0002418) | 2.85986367 |
22 | Molar tooth sign on MRI (HP:0002419) | 2.85986367 |
23 | Renal Fanconi syndrome (HP:0001994) | 2.85292524 |
24 | T lymphocytopenia (HP:0005403) | 2.83948055 |
25 | Hypoproteinemia (HP:0003075) | 2.83733385 |
26 | Cerebral edema (HP:0002181) | 2.83275526 |
27 | Periorbital edema (HP:0100539) | 2.80836864 |
28 | Hepatic necrosis (HP:0002605) | 2.76168474 |
29 | Reticulocytopenia (HP:0001896) | 2.74818610 |
30 | Nemaline bodies (HP:0003798) | 2.74809281 |
31 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.73675470 |
32 | Facial edema (HP:0000282) | 2.65775446 |
33 | Abnormality of T cell number (HP:0011839) | 2.56867605 |
34 | Increased muscle lipid content (HP:0009058) | 2.56210087 |
35 | Exertional dyspnea (HP:0002875) | 2.49447608 |
36 | Abnormality of the prostate (HP:0008775) | 2.47886933 |
37 | Abnormal finger flexion creases (HP:0006143) | 2.47781812 |
38 | Abnormal number of erythroid precursors (HP:0012131) | 2.40098546 |
39 | Mask-like facies (HP:0000298) | 2.37925160 |
40 | Pancreatic fibrosis (HP:0100732) | 2.36677000 |
41 | Round ear (HP:0100830) | 2.36401006 |
42 | Severe combined immunodeficiency (HP:0004430) | 2.35608688 |
43 | Optic disc pallor (HP:0000543) | 2.33697475 |
44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.32132499 |
45 | Macrocytic anemia (HP:0001972) | 2.31967717 |
46 | Increased serum lactate (HP:0002151) | 2.29603472 |
47 | Myotonia (HP:0002486) | 2.28330920 |
48 | Pancreatic cysts (HP:0001737) | 2.26747891 |
49 | Ulnar deviation of the wrist (HP:0003049) | 2.22800793 |
50 | Exercise intolerance (HP:0003546) | 2.20955197 |
51 | Increased IgM level (HP:0003496) | 2.20474580 |
52 | Autoimmune hemolytic anemia (HP:0001890) | 2.20333586 |
53 | Muscle fiber inclusion bodies (HP:0100299) | 2.19543079 |
54 | Type 2 muscle fiber atrophy (HP:0003554) | 2.18989580 |
55 | Abolished electroretinogram (ERG) (HP:0000550) | 2.18498679 |
56 | Calcaneovalgus deformity (HP:0001848) | 2.18265095 |
57 | Pendular nystagmus (HP:0012043) | 2.17854827 |
58 | Reduced antithrombin III activity (HP:0001976) | 2.15664357 |
59 | Lactic acidosis (HP:0003128) | 2.13971460 |
60 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.12014110 |
61 | True hermaphroditism (HP:0010459) | 2.11923159 |
62 | Pancytopenia (HP:0001876) | 2.10716934 |
63 | Deformed tarsal bones (HP:0008119) | 2.09780375 |
64 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.05261835 |
65 | Lethargy (HP:0001254) | 2.04015421 |
66 | Abnormal drinking behavior (HP:0030082) | 2.03152380 |
67 | Polydipsia (HP:0001959) | 2.03152380 |
68 | Abnormality of T cells (HP:0002843) | 2.03053142 |
69 | Oligomenorrhea (HP:0000876) | 2.01937472 |
70 | Abnormality of B cell number (HP:0010975) | 2.01754054 |
71 | B lymphocytopenia (HP:0010976) | 1.99894639 |
72 | Exercise-induced myalgia (HP:0003738) | 1.99848804 |
73 | Type II lissencephaly (HP:0007260) | 1.98204088 |
74 | Pallor (HP:0000980) | 1.96472421 |
75 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.93342256 |
76 | Thyroiditis (HP:0100646) | 1.91273950 |
77 | Hypoplasia of the fovea (HP:0007750) | 1.90158243 |
78 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.90158243 |
79 | Muscle fiber atrophy (HP:0100295) | 1.87934062 |
80 | Decreased circulating renin level (HP:0003351) | 1.85682947 |
81 | Constricted visual fields (HP:0001133) | 1.83301551 |
82 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.83092600 |
83 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.83092600 |
84 | Attenuation of retinal blood vessels (HP:0007843) | 1.82780049 |
85 | Stomatitis (HP:0010280) | 1.82657606 |
86 | Pigmentary retinal degeneration (HP:0001146) | 1.82481299 |
87 | Abnormality of renal resorption (HP:0011038) | 1.80341114 |
88 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.79686938 |
89 | Hypoalbuminemia (HP:0003073) | 1.79350697 |
90 | Abnormal albumin level (HP:0012116) | 1.79350697 |
91 | Abnormality of the fovea (HP:0000493) | 1.79342116 |
92 | Decreased central vision (HP:0007663) | 1.78960773 |
93 | Asplenia (HP:0001746) | 1.77926818 |
94 | IgM deficiency (HP:0002850) | 1.77448896 |
95 | Nephronophthisis (HP:0000090) | 1.77005073 |
96 | Respiratory failure (HP:0002878) | 1.76609338 |
97 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.75630160 |
98 | Severe visual impairment (HP:0001141) | 1.74036113 |
99 | Polyuria (HP:0000103) | 1.73639505 |
100 | Hyperglycinemia (HP:0002154) | 1.73526184 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TXK | 4.69565112 |
2 | TESK2 | 4.05998860 |
3 | KDR | 3.95676645 |
4 | BCKDK | 3.17741194 |
5 | MAP4K1 | 2.86183305 |
6 | VRK2 | 2.65685955 |
7 | TIE1 | 2.39351180 |
8 | WNK4 | 2.36158338 |
9 | GRK1 | 2.34129466 |
10 | MAP3K12 | 2.26527202 |
11 | ADRBK2 | 2.14974021 |
12 | TLK1 | 2.08118464 |
13 | OBSCN | 2.05477075 |
14 | ZAK | 2.01926720 |
15 | PHKG1 | 1.81684285 |
16 | PHKG2 | 1.81684285 |
17 | MAP4K2 | 1.78360944 |
18 | MAPK13 | 1.71650583 |
19 | NUAK1 | 1.67653241 |
20 | ITK | 1.66754321 |
21 | TYRO3 | 1.62867248 |
22 | PIK3CA | 1.62437929 |
23 | DYRK2 | 1.53410442 |
24 | VRK1 | 1.47457278 |
25 | MAP3K11 | 1.44387747 |
26 | LIMK1 | 1.42677274 |
27 | MST4 | 1.29600659 |
28 | CDK19 | 1.26004919 |
29 | MUSK | 1.19538368 |
30 | SYK | 1.17984911 |
31 | JAK3 | 1.15220329 |
32 | FES | 1.15137074 |
33 | TAOK3 | 1.10896469 |
34 | TEC | 1.09871684 |
35 | MAPKAPK3 | 1.08986015 |
36 | PRKCQ | 1.07785044 |
37 | SCYL2 | 1.06310613 |
38 | INSRR | 0.98410753 |
39 | CAMKK2 | 0.97627312 |
40 | OXSR1 | 0.95307058 |
41 | PRKCI | 0.95128509 |
42 | STK16 | 0.91106133 |
43 | PIK3CG | 0.88848932 |
44 | BTK | 0.87034723 |
45 | DAPK3 | 0.83443136 |
46 | TESK1 | 0.81989392 |
47 | CSK | 0.81692052 |
48 | BMPR2 | 0.80724126 |
49 | LCK | 0.80715069 |
50 | BMPR1B | 0.80436463 |
51 | WNK1 | 0.78799461 |
52 | AURKA | 0.78322593 |
53 | FRK | 0.78240243 |
54 | RPS6KA5 | 0.78060583 |
55 | PINK1 | 0.76993904 |
56 | DAPK2 | 0.76019274 |
57 | TAOK2 | 0.72004904 |
58 | DAPK1 | 0.71795246 |
59 | GRK6 | 0.71373847 |
60 | PRKCG | 0.70070681 |
61 | GRK7 | 0.69461182 |
62 | WNK3 | 0.69395136 |
63 | STK39 | 0.68677072 |
64 | MYLK | 0.67935773 |
65 | CHEK2 | 0.64787404 |
66 | CAMK1 | 0.62156184 |
67 | PIM2 | 0.61844088 |
68 | IKBKB | 0.61451126 |
69 | RIPK1 | 0.58185805 |
70 | PLK4 | 0.57080326 |
71 | PIM1 | 0.53618778 |
72 | BUB1 | 0.52464036 |
73 | PRKACA | 0.50702612 |
74 | ADRBK1 | 0.50466298 |
75 | CAMKK1 | 0.49920317 |
76 | LYN | 0.47690270 |
77 | NME1 | 0.46972846 |
78 | ATR | 0.44208285 |
79 | PRKCA | 0.43336023 |
80 | LRRK2 | 0.42276060 |
81 | CSNK2A1 | 0.41964437 |
82 | CSNK1G3 | 0.41650920 |
83 | PRKCD | 0.41601832 |
84 | CSNK2A2 | 0.38464513 |
85 | TNK2 | 0.37239875 |
86 | PKN1 | 0.36632430 |
87 | CAMK2G | 0.36599231 |
88 | CSNK1A1 | 0.35339682 |
89 | KIT | 0.32484050 |
90 | MAP2K7 | 0.31976927 |
91 | CSNK1G1 | 0.31437554 |
92 | FYN | 0.30828938 |
93 | ABL2 | 0.30545027 |
94 | PASK | 0.30188996 |
95 | CASK | 0.29820824 |
96 | TAF1 | 0.29108989 |
97 | ILK | 0.28254229 |
98 | PRKCE | 0.27721282 |
99 | IGF1R | 0.27654238 |
100 | PRKCB | 0.26422912 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 4.74198594 |
2 | Proteasome_Homo sapiens_hsa03050 | 4.11730914 |
3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.06529706 |
4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.70118803 |
5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.45831595 |
6 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.45110926 |
7 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.44592960 |
8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.38284619 |
9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.35908786 |
10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.25946837 |
11 | Allograft rejection_Homo sapiens_hsa05330 | 2.20576983 |
12 | RNA polymerase_Homo sapiens_hsa03020 | 2.16392500 |
13 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.13810139 |
14 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.13730123 |
15 | Asthma_Homo sapiens_hsa05310 | 1.97280048 |
16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.89987029 |
17 | Protein export_Homo sapiens_hsa03060 | 1.79588398 |
18 | Phototransduction_Homo sapiens_hsa04744 | 1.76057175 |
19 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.72045171 |
20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.63539363 |
21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.63240730 |
22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57011961 |
23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.49719620 |
24 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.49619713 |
25 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.42006740 |
26 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.40871517 |
27 | RNA degradation_Homo sapiens_hsa03018 | 1.32202697 |
28 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.15093495 |
29 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.12542305 |
30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.12246187 |
31 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.11457449 |
32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.10279236 |
33 | Homologous recombination_Homo sapiens_hsa03440 | 1.09710636 |
34 | Sulfur relay system_Homo sapiens_hsa04122 | 1.02405657 |
35 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.02065687 |
36 | Olfactory transduction_Homo sapiens_hsa04740 | 1.01433936 |
37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.00775138 |
38 | Peroxisome_Homo sapiens_hsa04146 | 1.00202394 |
39 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.96775560 |
40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.86708026 |
41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85247785 |
42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.84221857 |
43 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.81749398 |
44 | Purine metabolism_Homo sapiens_hsa00230 | 0.81606098 |
45 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.79403181 |
46 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.78858818 |
47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.76543982 |
48 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.75111206 |
49 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.73816395 |
50 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.73076003 |
51 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.69900975 |
52 | Basal transcription factors_Homo sapiens_hsa03022 | 0.69622118 |
53 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.69260182 |
54 | Viral myocarditis_Homo sapiens_hsa05416 | 0.69005635 |
55 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68491034 |
56 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.67373099 |
57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.65426168 |
58 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.64865740 |
59 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63145826 |
60 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.61209955 |
61 | Measles_Homo sapiens_hsa05162 | 0.60993646 |
62 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.57293302 |
63 | Spliceosome_Homo sapiens_hsa03040 | 0.56531713 |
64 | Nicotine addiction_Homo sapiens_hsa05033 | 0.55209824 |
65 | Mismatch repair_Homo sapiens_hsa03430 | 0.54724319 |
66 | Morphine addiction_Homo sapiens_hsa05032 | 0.52981095 |
67 | Tight junction_Homo sapiens_hsa04530 | 0.52507163 |
68 | DNA replication_Homo sapiens_hsa03030 | 0.51393408 |
69 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49981434 |
70 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.48121778 |
71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47251809 |
72 | Base excision repair_Homo sapiens_hsa03410 | 0.40637440 |
73 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.39714683 |
74 | Malaria_Homo sapiens_hsa05144 | 0.38050580 |
75 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.37301184 |
76 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.36782242 |
77 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.33048497 |
78 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.30370321 |
79 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.28841550 |
80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.28642759 |
81 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.28480713 |
82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.28253832 |
83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.28110641 |
84 | RNA transport_Homo sapiens_hsa03013 | 0.27640223 |
85 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.27602195 |
86 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.27530191 |
87 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.27012089 |
88 | Taste transduction_Homo sapiens_hsa04742 | 0.26732313 |
89 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.26708258 |
90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.26220716 |
91 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25291778 |
92 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.24121329 |
93 | GABAergic synapse_Homo sapiens_hsa04727 | 0.23211605 |
94 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.22529462 |
95 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.20662124 |
96 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.18316133 |
97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.18244342 |
98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.14864386 |
99 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.14632757 |
100 | Shigellosis_Homo sapiens_hsa05131 | 0.14094904 |