

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | maturation of SSU-rRNA (GO:0030490) | 9.77501385 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 9.50394694 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 9.43194487 |
| 4 | viral transcription (GO:0019083) | 8.19441459 |
| 5 | translational termination (GO:0006415) | 7.82176502 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.75574170 |
| 7 | substrate-independent telencephalic tangential migration (GO:0021826) | 6.72615732 |
| 8 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 6.72615732 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 6.66168286 |
| 10 | protein targeting to ER (GO:0045047) | 6.60769494 |
| 11 | translational elongation (GO:0006414) | 6.49534565 |
| 12 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.40952225 |
| 13 | protein localization to endoplasmic reticulum (GO:0070972) | 6.29968807 |
| 14 | cellular protein complex disassembly (GO:0043624) | 5.92928908 |
| 15 | chaperone-mediated protein transport (GO:0072321) | 5.89766700 |
| 16 | viral life cycle (GO:0019058) | 5.81772346 |
| 17 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.72781480 |
| 18 | ATP synthesis coupled proton transport (GO:0015986) | 5.51657373 |
| 19 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.51657373 |
| 20 | translational initiation (GO:0006413) | 5.46362686 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.12194445 |
| 22 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.99030384 |
| 23 | protein complex disassembly (GO:0043241) | 4.92794184 |
| 24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.86570535 |
| 25 | macromolecular complex disassembly (GO:0032984) | 4.71467663 |
| 26 | translation (GO:0006412) | 4.57586178 |
| 27 | protein targeting to membrane (GO:0006612) | 4.56985124 |
| 28 | respiratory electron transport chain (GO:0022904) | 4.49243013 |
| 29 | electron transport chain (GO:0022900) | 4.40401805 |
| 30 | positive regulation of respiratory burst (GO:0060267) | 4.35586866 |
| 31 | nonmotile primary cilium assembly (GO:0035058) | 4.33896666 |
| 32 | tongue development (GO:0043586) | 4.31848749 |
| 33 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.24279824 |
| 34 | ribosomal large subunit biogenesis (GO:0042273) | 4.15691308 |
| 35 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.15481192 |
| 36 | GTP biosynthetic process (GO:0006183) | 4.00401887 |
| 37 | cellular component biogenesis (GO:0044085) | 3.93624708 |
| 38 | mRNA catabolic process (GO:0006402) | 3.90907186 |
| 39 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.89452597 |
| 40 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.86239927 |
| 41 | positive regulation of T cell apoptotic process (GO:0070234) | 3.75362067 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.72090741 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.72090741 |
| 44 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.72090741 |
| 45 | protein complex biogenesis (GO:0070271) | 3.68902569 |
| 46 | rRNA processing (GO:0006364) | 3.61063252 |
| 47 | cardiovascular system development (GO:0072358) | 3.60992105 |
| 48 | UTP biosynthetic process (GO:0006228) | 3.60131940 |
| 49 | DNA deamination (GO:0045006) | 3.59571897 |
| 50 | axonemal dynein complex assembly (GO:0070286) | 3.54797569 |
| 51 | RNA catabolic process (GO:0006401) | 3.52210364 |
| 52 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.51991984 |
| 53 | behavioral response to nicotine (GO:0035095) | 3.50708665 |
| 54 | UTP metabolic process (GO:0046051) | 3.50322358 |
| 55 | rRNA metabolic process (GO:0016072) | 3.49539856 |
| 56 | spliceosomal complex assembly (GO:0000245) | 3.48629676 |
| 57 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.43389085 |
| 58 | L-serine metabolic process (GO:0006563) | 3.40357734 |
| 59 | protein-cofactor linkage (GO:0018065) | 3.39892848 |
| 60 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.38612243 |
| 61 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.34155410 |
| 62 | somite development (GO:0061053) | 3.32909699 |
| 63 | protein targeting to mitochondrion (GO:0006626) | 3.29666638 |
| 64 | left/right axis specification (GO:0070986) | 3.25766605 |
| 65 | ATP biosynthetic process (GO:0006754) | 3.25385042 |
| 66 | establishment of protein localization to mitochondrion (GO:0072655) | 3.22633518 |
| 67 | establishment of protein localization to membrane (GO:0090150) | 3.21217347 |
| 68 | protein neddylation (GO:0045116) | 3.19417849 |
| 69 | DNA damage response, detection of DNA damage (GO:0042769) | 3.19073722 |
| 70 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.14951103 |
| 71 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.14951103 |
| 72 | cerebral cortex radially oriented cell migration (GO:0021799) | 3.14341528 |
| 73 | regulation of cellular respiration (GO:0043457) | 3.14124640 |
| 74 | protein targeting (GO:0006605) | 3.13300313 |
| 75 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.06676675 |
| 76 | hydrogen ion transmembrane transport (GO:1902600) | 3.01859273 |
| 77 | protein localization to mitochondrion (GO:0070585) | 2.97479618 |
| 78 | peptidyl-histidine modification (GO:0018202) | 2.92346894 |
| 79 | establishment of protein localization to organelle (GO:0072594) | 2.92105343 |
| 80 | CTP metabolic process (GO:0046036) | 2.90139388 |
| 81 | CTP biosynthetic process (GO:0006241) | 2.90139388 |
| 82 | ncRNA 3-end processing (GO:0043628) | 2.88965062 |
| 83 | regulation of mitochondrial translation (GO:0070129) | 2.88434756 |
| 84 | rRNA modification (GO:0000154) | 2.87582029 |
| 85 | outer ear morphogenesis (GO:0042473) | 2.85005127 |
| 86 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.83872976 |
| 87 | mature B cell differentiation involved in immune response (GO:0002313) | 2.83287584 |
| 88 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.80234546 |
| 89 | negative regulation of B cell apoptotic process (GO:0002903) | 2.79401917 |
| 90 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.74533500 |
| 91 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.73294565 |
| 92 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.73107738 |
| 93 | neuron fate determination (GO:0048664) | 2.71465431 |
| 94 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.70138724 |
| 95 | negative regulation of telomere maintenance (GO:0032205) | 2.68803434 |
| 96 | proton transport (GO:0015992) | 2.68170236 |
| 97 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 2.67181232 |
| 98 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.64845262 |
| 99 | indolalkylamine metabolic process (GO:0006586) | 2.63116106 |
| 100 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.63018051 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.52115685 |
| 2 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.26842009 |
| 3 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 4.47726947 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.27107695 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.77089662 |
| 6 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.27872030 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.26856038 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.24223195 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.19555425 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.11009666 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.91066114 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.72039837 |
| 13 | VDR_22108803_ChIP-Seq_LS180_Human | 2.19362305 |
| 14 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.11985348 |
| 15 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.03457567 |
| 16 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.00316051 |
| 17 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.86087768 |
| 18 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.86050003 |
| 19 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83452683 |
| 20 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.80589284 |
| 21 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.79487389 |
| 22 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.76884240 |
| 23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.76431828 |
| 24 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.74877130 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.73002234 |
| 26 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.54774121 |
| 27 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.54452164 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.53716474 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.50533615 |
| 30 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.46675105 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.44558415 |
| 32 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.43638531 |
| 33 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.38525602 |
| 34 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.37898981 |
| 35 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.36816555 |
| 36 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.35672797 |
| 37 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.33248048 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.33221270 |
| 39 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.31264760 |
| 40 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30028409 |
| 41 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.29869318 |
| 42 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.18336052 |
| 43 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.18277683 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.17118857 |
| 45 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.17010915 |
| 46 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.15652936 |
| 47 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.15144884 |
| 48 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.12958775 |
| 49 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.12687908 |
| 50 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.12212038 |
| 51 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.12209681 |
| 52 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.10559563 |
| 53 | FUS_26573619_Chip-Seq_HEK293_Human | 1.07793529 |
| 54 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.07514717 |
| 55 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.06581932 |
| 56 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.05628491 |
| 57 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05473655 |
| 58 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.03909256 |
| 59 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03817755 |
| 60 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.02669058 |
| 61 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.02286854 |
| 62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.02072931 |
| 63 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.01417437 |
| 64 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.01233326 |
| 65 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.01058745 |
| 66 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.00899088 |
| 67 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.00793180 |
| 68 | ERA_21632823_ChIP-Seq_H3396_Human | 0.99803391 |
| 69 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.99038205 |
| 70 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.98206348 |
| 71 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.97996720 |
| 72 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.96888232 |
| 73 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.95713005 |
| 74 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 0.95616854 |
| 75 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.94631307 |
| 76 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.92553568 |
| 77 | EWS_26573619_Chip-Seq_HEK293_Human | 0.92116574 |
| 78 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.90689288 |
| 79 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.90657926 |
| 80 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89435792 |
| 81 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.88831634 |
| 82 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.88009656 |
| 83 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.85834520 |
| 84 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.85624883 |
| 85 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.84659075 |
| 86 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.83328097 |
| 87 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.82804536 |
| 88 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 0.82753672 |
| 89 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.82292498 |
| 90 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.82155243 |
| 91 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.82046362 |
| 92 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.81742124 |
| 93 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.79766456 |
| 94 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 0.77060323 |
| 95 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.77024433 |
| 96 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.77010750 |
| 97 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.76827163 |
| 98 | AR_20517297_ChIP-Seq_VCAP_Human | 0.76426345 |
| 99 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.75331729 |
| 100 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.74038129 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 8.87872910 |
| 2 | MP0006292_abnormal_olfactory_placode | 5.16862362 |
| 3 | MP0008789_abnormal_olfactory_epithelium | 2.98801527 |
| 4 | MP0003646_muscle_fatigue | 2.97221158 |
| 5 | MP0003878_abnormal_ear_physiology | 2.71162982 |
| 6 | MP0005377_hearing/vestibular/ear_phenot | 2.71162982 |
| 7 | MP0005499_abnormal_olfactory_system | 2.66161394 |
| 8 | MP0005394_taste/olfaction_phenotype | 2.66161394 |
| 9 | MP0002837_dystrophic_cardiac_calcinosis | 2.60399419 |
| 10 | MP0004142_abnormal_muscle_tone | 2.57675964 |
| 11 | MP0009053_abnormal_anal_canal | 2.26611676 |
| 12 | MP0003136_yellow_coat_color | 2.17717060 |
| 13 | MP0000049_abnormal_middle_ear | 2.02580994 |
| 14 | MP0002653_abnormal_ependyma_morphology | 1.96430621 |
| 15 | MP0005174_abnormal_tail_pigmentation | 1.88332698 |
| 16 | MP0001293_anophthalmia | 1.83900051 |
| 17 | MP0005670_abnormal_white_adipose | 1.81109417 |
| 18 | MP0001853_heart_inflammation | 1.76391324 |
| 19 | MP0003880_abnormal_central_pattern | 1.74109963 |
| 20 | MP0002277_abnormal_respiratory_mucosa | 1.69094776 |
| 21 | MP0002138_abnormal_hepatobiliary_system | 1.67450492 |
| 22 | MP0003122_maternal_imprinting | 1.66844308 |
| 23 | MP0006276_abnormal_autonomic_nervous | 1.57627510 |
| 24 | MP0004885_abnormal_endolymph | 1.57584957 |
| 25 | MP0001485_abnormal_pinna_reflex | 1.57419622 |
| 26 | MP0005360_urolithiasis | 1.54390985 |
| 27 | MP0003938_abnormal_ear_development | 1.46683126 |
| 28 | MP0002938_white_spotting | 1.39160486 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.37643851 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.32047953 |
| 31 | MP0002234_abnormal_pharynx_morphology | 1.31708661 |
| 32 | MP0002736_abnormal_nociception_after | 1.30490425 |
| 33 | MP0001529_abnormal_vocalization | 1.27868076 |
| 34 | MP0002095_abnormal_skin_pigmentation | 1.25081049 |
| 35 | MP0002876_abnormal_thyroid_physiology | 1.23423681 |
| 36 | MP0000678_abnormal_parathyroid_gland | 1.21213510 |
| 37 | MP0000778_abnormal_nervous_system | 1.20835873 |
| 38 | MP0004742_abnormal_vestibular_system | 1.19517001 |
| 39 | MP0004145_abnormal_muscle_electrophysio | 1.19039977 |
| 40 | MP0002249_abnormal_larynx_morphology | 1.19006374 |
| 41 | MP0002233_abnormal_nose_morphology | 1.18820744 |
| 42 | MP0005084_abnormal_gallbladder_morpholo | 1.17408202 |
| 43 | MP0003567_abnormal_fetal_cardiomyocyte | 1.16628390 |
| 44 | MP0002272_abnormal_nervous_system | 1.14184309 |
| 45 | MP0004147_increased_porphyrin_level | 1.13644220 |
| 46 | MP0001188_hyperpigmentation | 1.10385688 |
| 47 | MP0010030_abnormal_orbit_morphology | 1.08924337 |
| 48 | MP0002160_abnormal_reproductive_system | 1.08801803 |
| 49 | MP0004133_heterotaxia | 1.08200097 |
| 50 | MP0003186_abnormal_redox_activity | 1.08171852 |
| 51 | MP0001905_abnormal_dopamine_level | 1.07893661 |
| 52 | MP0005551_abnormal_eye_electrophysiolog | 1.05593198 |
| 53 | MP0000566_synostosis | 1.05230701 |
| 54 | MP0003123_paternal_imprinting | 1.03447882 |
| 55 | MP0003121_genomic_imprinting | 1.03369329 |
| 56 | MP0005646_abnormal_pituitary_gland | 1.03000296 |
| 57 | MP0006036_abnormal_mitochondrial_physio | 1.02631605 |
| 58 | MP0000631_abnormal_neuroendocrine_gland | 0.98689093 |
| 59 | MP0008995_early_reproductive_senescence | 0.97027497 |
| 60 | MP0008872_abnormal_physiological_respon | 0.96551913 |
| 61 | MP0000569_abnormal_digit_pigmentation | 0.94173301 |
| 62 | MP0001986_abnormal_taste_sensitivity | 0.92347134 |
| 63 | MP0003879_abnormal_hair_cell | 0.90592642 |
| 64 | MP0002184_abnormal_innervation | 0.89453211 |
| 65 | MP0005195_abnormal_posterior_eye | 0.88145476 |
| 66 | MP0000026_abnormal_inner_ear | 0.87310560 |
| 67 | MP0001440_abnormal_grooming_behavior | 0.84583171 |
| 68 | MP0001984_abnormal_olfaction | 0.83947827 |
| 69 | MP0005332_abnormal_amino_acid | 0.83487982 |
| 70 | MP0008877_abnormal_DNA_methylation | 0.81888598 |
| 71 | MP0003755_abnormal_palate_morphology | 0.81658787 |
| 72 | MP0005085_abnormal_gallbladder_physiolo | 0.80347838 |
| 73 | MP0003937_abnormal_limbs/digits/tail_de | 0.79927412 |
| 74 | MP0000516_abnormal_urinary_system | 0.77333588 |
| 75 | MP0005367_renal/urinary_system_phenotyp | 0.77333588 |
| 76 | MP0005389_reproductive_system_phenotype | 0.76870252 |
| 77 | MP0000955_abnormal_spinal_cord | 0.76760792 |
| 78 | MP0008775_abnormal_heart_ventricle | 0.76106882 |
| 79 | MP0002557_abnormal_social/conspecific_i | 0.75553144 |
| 80 | MP0009250_abnormal_appendicular_skeleto | 0.74547854 |
| 81 | MP0002177_abnormal_outer_ear | 0.73474332 |
| 82 | MP0001324_abnormal_eye_pigmentation | 0.73432878 |
| 83 | MP0003942_abnormal_urinary_system | 0.71683807 |
| 84 | MP0002752_abnormal_somatic_nervous | 0.70265352 |
| 85 | MP0002102_abnormal_ear_morphology | 0.70053055 |
| 86 | MP0009046_muscle_twitch | 0.69480119 |
| 87 | MP0005636_abnormal_mineral_homeostasis | 0.68651887 |
| 88 | MP0001486_abnormal_startle_reflex | 0.67406769 |
| 89 | MP0009745_abnormal_behavioral_response | 0.67385303 |
| 90 | MP0008875_abnormal_xenobiotic_pharmacok | 0.67219101 |
| 91 | MP0002733_abnormal_thermal_nociception | 0.65864391 |
| 92 | MP0000604_amyloidosis | 0.62859515 |
| 93 | MP0003786_premature_aging | 0.62081405 |
| 94 | MP0002210_abnormal_sex_determination | 0.61219689 |
| 95 | MP0001963_abnormal_hearing_physiology | 0.60615217 |
| 96 | MP0001286_abnormal_eye_development | 0.59289345 |
| 97 | MP0002067_abnormal_sensory_capabilities | 0.59093848 |
| 98 | MP0002572_abnormal_emotion/affect_behav | 0.58212346 |
| 99 | MP0006035_abnormal_mitochondrial_morpho | 0.58091010 |
| 100 | MP0002928_abnormal_bile_duct | 0.57776037 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 7.01881961 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 5.14011563 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.73984865 |
| 4 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 4.71313021 |
| 5 | Molar tooth sign on MRI (HP:0002419) | 4.65225890 |
| 6 | Abnormality of midbrain morphology (HP:0002418) | 4.65225890 |
| 7 | Acute encephalopathy (HP:0006846) | 4.63028725 |
| 8 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.48028137 |
| 9 | Macrocytic anemia (HP:0001972) | 4.27690073 |
| 10 | Progressive macrocephaly (HP:0004481) | 4.08497493 |
| 11 | Mitochondrial inheritance (HP:0001427) | 3.90060835 |
| 12 | 11 pairs of ribs (HP:0000878) | 3.70953070 |
| 13 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.61939371 |
| 14 | Cerebral edema (HP:0002181) | 3.44104042 |
| 15 | Abnormal number of erythroid precursors (HP:0012131) | 3.41171565 |
| 16 | Increased CSF lactate (HP:0002490) | 3.40500981 |
| 17 | Increased hepatocellular lipid droplets (HP:0006565) | 3.20891365 |
| 18 | Septo-optic dysplasia (HP:0100842) | 3.18863684 |
| 19 | Absent thumb (HP:0009777) | 3.17914000 |
| 20 | Pallor (HP:0000980) | 3.11725207 |
| 21 | Rib fusion (HP:0000902) | 3.01178337 |
| 22 | Absent/shortened dynein arms (HP:0200106) | 2.97479438 |
| 23 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.97479438 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 2.92325375 |
| 25 | Nephronophthisis (HP:0000090) | 2.90052376 |
| 26 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.84992006 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.77339444 |
| 28 | Hepatic necrosis (HP:0002605) | 2.71022487 |
| 29 | Partial duplication of thumb phalanx (HP:0009944) | 2.65606245 |
| 30 | Hypoplasia of the radius (HP:0002984) | 2.64532354 |
| 31 | Hepatocellular necrosis (HP:0001404) | 2.62326960 |
| 32 | Colon cancer (HP:0003003) | 2.56189578 |
| 33 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.54361385 |
| 34 | Missing ribs (HP:0000921) | 2.50283969 |
| 35 | Stenosis of the external auditory canal (HP:0000402) | 2.46755442 |
| 36 | Hyperglycinemia (HP:0002154) | 2.44132071 |
| 37 | Leukodystrophy (HP:0002415) | 2.39296890 |
| 38 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.38002670 |
| 39 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.38002670 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.35546867 |
| 41 | Tubular atrophy (HP:0000092) | 2.32490352 |
| 42 | Supernumerary spleens (HP:0009799) | 2.30060523 |
| 43 | Abnormal ciliary motility (HP:0012262) | 2.30007494 |
| 44 | Sclerocornea (HP:0000647) | 2.23555503 |
| 45 | Optic disc pallor (HP:0000543) | 2.23544619 |
| 46 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.22159936 |
| 47 | Lethargy (HP:0001254) | 2.21301377 |
| 48 | Myokymia (HP:0002411) | 2.21162152 |
| 49 | Abnormality of the 4th metacarpal (HP:0010012) | 2.20180604 |
| 50 | Abnormality of the diencephalon (HP:0010662) | 2.19840222 |
| 51 | Partial duplication of the phalanx of hand (HP:0009999) | 2.18374888 |
| 52 | Abnormality of the renal medulla (HP:0100957) | 2.14409657 |
| 53 | Maternal diabetes (HP:0009800) | 2.13747145 |
| 54 | Lactic acidosis (HP:0003128) | 2.13317476 |
| 55 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.09656507 |
| 56 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.09656507 |
| 57 | Forearm undergrowth (HP:0009821) | 2.08964609 |
| 58 | Abnormality of urine glucose concentration (HP:0011016) | 2.08263712 |
| 59 | Glycosuria (HP:0003076) | 2.08263712 |
| 60 | Depressed nasal ridge (HP:0000457) | 2.08047715 |
| 61 | Anencephaly (HP:0002323) | 2.06801372 |
| 62 | Pancreatic fibrosis (HP:0100732) | 2.05879441 |
| 63 | Type II lissencephaly (HP:0007260) | 2.03476229 |
| 64 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.03011564 |
| 65 | Hyperphosphaturia (HP:0003109) | 2.00437635 |
| 66 | Abnormal drinking behavior (HP:0030082) | 1.97577813 |
| 67 | Polydipsia (HP:0001959) | 1.97577813 |
| 68 | Pendular nystagmus (HP:0012043) | 1.96960133 |
| 69 | Absent septum pellucidum (HP:0001331) | 1.95552305 |
| 70 | Increased serum lactate (HP:0002151) | 1.95363831 |
| 71 | Respiratory failure (HP:0002878) | 1.94864252 |
| 72 | 3-Methylglutaconic aciduria (HP:0003535) | 1.93073954 |
| 73 | Abnormality of the metopic suture (HP:0005556) | 1.92928468 |
| 74 | Triphalangeal thumb (HP:0001199) | 1.90377376 |
| 75 | Medial flaring of the eyebrow (HP:0010747) | 1.89140084 |
| 76 | Exercise intolerance (HP:0003546) | 1.88586893 |
| 77 | Increased muscle lipid content (HP:0009058) | 1.87426531 |
| 78 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.87301305 |
| 79 | Abnormality of alanine metabolism (HP:0010916) | 1.87301305 |
| 80 | Hyperalaninemia (HP:0003348) | 1.87301305 |
| 81 | True hermaphroditism (HP:0010459) | 1.86706992 |
| 82 | Abnormality of renal resorption (HP:0011038) | 1.85770365 |
| 83 | Renal dysplasia (HP:0000110) | 1.85116446 |
| 84 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.85002111 |
| 85 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.83450082 |
| 86 | Optic nerve hypoplasia (HP:0000609) | 1.82306418 |
| 87 | Generalized aminoaciduria (HP:0002909) | 1.81271073 |
| 88 | Pancreatic cysts (HP:0001737) | 1.81230574 |
| 89 | Hyperglycinuria (HP:0003108) | 1.80967738 |
| 90 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 1.80948237 |
| 91 | Hip dysplasia (HP:0001385) | 1.79496865 |
| 92 | Fibular hypoplasia (HP:0003038) | 1.77904155 |
| 93 | Exertional dyspnea (HP:0002875) | 1.77717837 |
| 94 | Abnormal number of incisors (HP:0011064) | 1.77573112 |
| 95 | Respiratory difficulties (HP:0002880) | 1.77394728 |
| 96 | Duplication of thumb phalanx (HP:0009942) | 1.77248771 |
| 97 | Asplenia (HP:0001746) | 1.75954310 |
| 98 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.75176263 |
| 99 | Constricted visual fields (HP:0001133) | 1.74964316 |
| 100 | Abnormal hemoglobin (HP:0011902) | 1.74234344 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME2 | 4.21389869 |
| 2 | WNK4 | 3.55923352 |
| 3 | MAP3K9 | 3.23663352 |
| 4 | CASK | 2.76595053 |
| 5 | DYRK2 | 2.47814836 |
| 6 | BCKDK | 2.45680617 |
| 7 | STK16 | 2.36443020 |
| 8 | ARAF | 2.35738816 |
| 9 | STK39 | 2.31107194 |
| 10 | PINK1 | 2.14453440 |
| 11 | LRRK2 | 2.08600185 |
| 12 | LIMK1 | 2.08257135 |
| 13 | EPHB2 | 2.03058685 |
| 14 | MAP3K12 | 2.02306438 |
| 15 | PDK2 | 2.02194871 |
| 16 | BRAF | 1.82979176 |
| 17 | TRIM28 | 1.81086350 |
| 18 | TLK1 | 1.77084962 |
| 19 | SRPK1 | 1.68107762 |
| 20 | PAK3 | 1.64339008 |
| 21 | GRK1 | 1.51749574 |
| 22 | OXSR1 | 1.39421703 |
| 23 | ADRBK2 | 1.34009764 |
| 24 | TIE1 | 1.32638994 |
| 25 | CDC7 | 1.32392837 |
| 26 | EPHA4 | 1.30488125 |
| 27 | PRKCG | 1.29132703 |
| 28 | MAP3K13 | 1.27450987 |
| 29 | MAP2K7 | 1.25585138 |
| 30 | WNK3 | 1.22299657 |
| 31 | MAP3K11 | 1.17243048 |
| 32 | NUAK1 | 1.12454541 |
| 33 | CSNK1E | 1.09351246 |
| 34 | CAMK1 | 1.08857770 |
| 35 | NTRK2 | 1.06458378 |
| 36 | PIM2 | 1.04998670 |
| 37 | BRSK1 | 1.01836149 |
| 38 | CSNK2A2 | 1.00301080 |
| 39 | MST4 | 0.97651358 |
| 40 | DAPK3 | 0.95489768 |
| 41 | FRK | 0.92994720 |
| 42 | TEC | 0.92555007 |
| 43 | ABL2 | 0.90227152 |
| 44 | INSRR | 0.87295238 |
| 45 | ATR | 0.83947481 |
| 46 | WNK1 | 0.83774429 |
| 47 | MYLK | 0.82994037 |
| 48 | PLK1 | 0.81533519 |
| 49 | PRKCQ | 0.79038070 |
| 50 | PLK4 | 0.77731401 |
| 51 | AURKB | 0.76391474 |
| 52 | PRKACA | 0.75082317 |
| 53 | NME1 | 0.74639972 |
| 54 | OBSCN | 0.74338387 |
| 55 | TXK | 0.74148526 |
| 56 | BTK | 0.73171356 |
| 57 | ILK | 0.72638829 |
| 58 | AURKA | 0.70980132 |
| 59 | RPS6KA6 | 0.70863389 |
| 60 | MARK1 | 0.69594941 |
| 61 | PIK3CA | 0.68892745 |
| 62 | VRK2 | 0.68843544 |
| 63 | TYRO3 | 0.66442071 |
| 64 | CCNB1 | 0.64947305 |
| 65 | ICK | 0.64814014 |
| 66 | MAP2K6 | 0.64632461 |
| 67 | ZAK | 0.63684093 |
| 68 | CSNK2A1 | 0.62697711 |
| 69 | MAPK13 | 0.61876097 |
| 70 | PHKG2 | 0.61318252 |
| 71 | PHKG1 | 0.61318252 |
| 72 | NTRK1 | 0.59649600 |
| 73 | MAPK15 | 0.57986119 |
| 74 | MAP2K4 | 0.56664821 |
| 75 | ADRBK1 | 0.56604333 |
| 76 | RPS6KA5 | 0.56200186 |
| 77 | MOS | 0.53656026 |
| 78 | CAMK2A | 0.53143033 |
| 79 | MINK1 | 0.52220829 |
| 80 | CHEK1 | 0.51784376 |
| 81 | PAK2 | 0.51337846 |
| 82 | DMPK | 0.49997396 |
| 83 | PTK2B | 0.49809324 |
| 84 | VRK1 | 0.49690796 |
| 85 | CSNK1A1 | 0.48089699 |
| 86 | CAMKK1 | 0.46075744 |
| 87 | IKBKB | 0.43543063 |
| 88 | PRKCA | 0.43286363 |
| 89 | RPS6KC1 | 0.43006293 |
| 90 | RPS6KL1 | 0.43006293 |
| 91 | SGK1 | 0.41048113 |
| 92 | PRKCI | 0.38183669 |
| 93 | STK11 | 0.37589646 |
| 94 | PRKCD | 0.37145073 |
| 95 | TAF1 | 0.36844087 |
| 96 | NEK1 | 0.36840839 |
| 97 | MUSK | 0.36266559 |
| 98 | AKT2 | 0.33086342 |
| 99 | PIM1 | 0.31781951 |
| 100 | BMPR1B | 0.31655984 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.73758848 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.43314839 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.80195363 |
| 4 | Huntingtons disease_Homo sapiens_hsa05016 | 2.80766647 |
| 5 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.75392133 |
| 6 | Alzheimers disease_Homo sapiens_hsa05010 | 2.67092183 |
| 7 | Asthma_Homo sapiens_hsa05310 | 2.37432412 |
| 8 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.31368896 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.16955294 |
| 10 | Protein export_Homo sapiens_hsa03060 | 1.96205516 |
| 11 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.77493735 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.76537597 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 1.70715528 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.68825111 |
| 15 | Proteasome_Homo sapiens_hsa03050 | 1.66042506 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.60670383 |
| 17 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.57020170 |
| 18 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.46294668 |
| 19 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.45424602 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.43115607 |
| 21 | Allograft rejection_Homo sapiens_hsa05330 | 1.41490371 |
| 22 | Mismatch repair_Homo sapiens_hsa03430 | 1.39319586 |
| 23 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.39223796 |
| 24 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.36645561 |
| 25 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.35534961 |
| 26 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.33904619 |
| 27 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.31847424 |
| 28 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.31212991 |
| 29 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.29559271 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.27054296 |
| 31 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.24211154 |
| 32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.22652935 |
| 33 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.20980755 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.19952315 |
| 35 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.19685918 |
| 36 | Basal transcription factors_Homo sapiens_hsa03022 | 1.17677948 |
| 37 | RNA degradation_Homo sapiens_hsa03018 | 1.16432561 |
| 38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.13823617 |
| 39 | Sulfur relay system_Homo sapiens_hsa04122 | 1.13154362 |
| 40 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.01539655 |
| 41 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.01315798 |
| 42 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.00134135 |
| 43 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.97471748 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 0.95888290 |
| 45 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.94065463 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.90303403 |
| 47 | Spliceosome_Homo sapiens_hsa03040 | 0.90160392 |
| 48 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.87032434 |
| 49 | DNA replication_Homo sapiens_hsa03030 | 0.84085186 |
| 50 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.83038450 |
| 51 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.82876467 |
| 52 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.82093548 |
| 53 | Retinol metabolism_Homo sapiens_hsa00830 | 0.81643359 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.77726045 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76043028 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.75130731 |
| 57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.71917175 |
| 58 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.70120212 |
| 59 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.69299948 |
| 60 | RNA transport_Homo sapiens_hsa03013 | 0.67061577 |
| 61 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.65481653 |
| 62 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.63943332 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.63048767 |
| 64 | Nicotine addiction_Homo sapiens_hsa05033 | 0.61408873 |
| 65 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.59103416 |
| 66 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.57786739 |
| 67 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.55475135 |
| 68 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53069087 |
| 69 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.51687116 |
| 70 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.51669850 |
| 71 | Purine metabolism_Homo sapiens_hsa00230 | 0.51521671 |
| 72 | Phototransduction_Homo sapiens_hsa04744 | 0.51101099 |
| 73 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.50257630 |
| 74 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.48343483 |
| 75 | Histidine metabolism_Homo sapiens_hsa00340 | 0.47108047 |
| 76 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45471599 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.41954237 |
| 78 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.39884570 |
| 79 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.38359975 |
| 80 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.37188159 |
| 81 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.35701384 |
| 82 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.34117691 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.33705691 |
| 84 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.33634128 |
| 85 | Mineral absorption_Homo sapiens_hsa04978 | 0.32704660 |
| 86 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.32059543 |
| 87 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.31183232 |
| 88 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.26693045 |
| 89 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.26236492 |
| 90 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25632522 |
| 91 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.25571861 |
| 92 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.24727606 |
| 93 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.21755308 |
| 94 | Base excision repair_Homo sapiens_hsa03410 | 0.20190907 |
| 95 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.19959155 |
| 96 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.19325792 |
| 97 | Olfactory transduction_Homo sapiens_hsa04740 | 0.18668840 |
| 98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.18526641 |
| 99 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.17721822 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.17511815 |

