RPL36AL

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which shares sequence similarity with yeast ribosomal protein L44, belongs to the L44E (L36AE) family of ribosomal proteins. This gene and the human gene officially named ribosomal protein L36a (RPL36A) encode nearly identical proteins; however, they are distinct genes. Although the name of this gene has been referred to as ribosomal protein L36a (RPL36A), its official name is ribosomal protein L36a-like (RPL36AL). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1viral transcription (GO:0019083)7.04159666
2ribosomal small subunit assembly (GO:0000028)6.91476874
3translational termination (GO:0006415)6.83415745
4SRP-dependent cotranslational protein targeting to membrane (GO:0006614)6.46603240
5ribosomal small subunit biogenesis (GO:0042274)6.40592732
6cotranslational protein targeting to membrane (GO:0006613)6.32632188
7protein targeting to ER (GO:0045047)6.32368246
8chaperone-mediated protein transport (GO:0072321)6.05320791
9establishment of protein localization to endoplasmic reticulum (GO:0072599)6.02522635
10translational elongation (GO:0006414)6.01408531
11protein localization to endoplasmic reticulum (GO:0070972)5.97565089
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)5.64666940
13electron transport chain (GO:0022900)5.51922320
14maturation of SSU-rRNA (GO:0030490)5.41241311
15translational initiation (GO:0006413)5.39416518
16DNA deamination (GO:0045006)5.37869348
17nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)5.33470613
18viral life cycle (GO:0019058)5.33209421
19cellular protein complex disassembly (GO:0043624)5.27306951
20ribosomal large subunit biogenesis (GO:0042273)5.05697275
21protein complex disassembly (GO:0043241)4.56809587
22* translation (GO:0006412)4.54188064
23protein complex biogenesis (GO:0070271)4.44260000
24protein neddylation (GO:0045116)4.35860109
25macromolecular complex disassembly (GO:0032984)4.31199447
26formation of translation preinitiation complex (GO:0001731)4.27709575
27ribonucleoprotein complex biogenesis (GO:0022613)4.26858921
28protein targeting to membrane (GO:0006612)4.18714719
29mitochondrial respiratory chain complex assembly (GO:0033108)4.18306362
30mitochondrial respiratory chain complex I assembly (GO:0032981)4.05830503
31NADH dehydrogenase complex assembly (GO:0010257)4.05830503
32mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.05830503
33nuclear-transcribed mRNA catabolic process (GO:0000956)3.96051754
34ATP biosynthetic process (GO:0006754)3.77019643
35folic acid-containing compound biosynthetic process (GO:0009396)3.76173870
36mRNA catabolic process (GO:0006402)3.75174467
37cytidine metabolic process (GO:0046087)3.74907058
38cytidine catabolic process (GO:0006216)3.74907058
39cytidine deamination (GO:0009972)3.74907058
40protein targeting to mitochondrion (GO:0006626)3.70084947
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.67816691
42telomere maintenance via semi-conservative replication (GO:0032201)3.67219272
43DNA strand elongation involved in DNA replication (GO:0006271)3.65475097
44hydrogen ion transmembrane transport (GO:1902600)3.64847626
45rRNA processing (GO:0006364)3.57383947
46RNA catabolic process (GO:0006401)3.56990662
47purine nucleoside triphosphate biosynthetic process (GO:0009145)3.55946146
48purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.55169253
49regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.49685492
50DNA strand elongation (GO:0022616)3.46667077
51establishment of protein localization to mitochondrion (GO:0072655)3.45776090
52rRNA metabolic process (GO:0016072)3.44077377
53proteasome assembly (GO:0043248)3.43111905
54cellular component biogenesis (GO:0044085)3.42808569
55cytochrome complex assembly (GO:0017004)3.42594366
56ATP synthesis coupled proton transport (GO:0015986)3.40898346
57energy coupled proton transport, down electrochemical gradient (GO:0015985)3.40898346
58ribosome assembly (GO:0042255)3.36686050
59nucleobase biosynthetic process (GO:0046112)3.36201052
60inner mitochondrial membrane organization (GO:0007007)3.31203246
61protein localization to mitochondrion (GO:0070585)3.31179696
62pteridine-containing compound biosynthetic process (GO:0042559)3.28215701
63respiratory chain complex IV assembly (GO:0008535)3.26740945
64negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.24497676
65deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.24178571
66ribosome biogenesis (GO:0042254)3.22353617
67proton transport (GO:0015992)3.21662914
68purine nucleobase biosynthetic process (GO:0009113)3.19817206
69telomere maintenance via recombination (GO:0000722)3.17909366
70DNA replication initiation (GO:0006270)3.15677568
71hydrogen transport (GO:0006818)3.14332820
72ribonucleoside triphosphate biosynthetic process (GO:0009201)3.13923199
73RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.13842455
74tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.13842455
75antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.12398526
76pseudouridine synthesis (GO:0001522)3.10576702
77spliceosomal snRNP assembly (GO:0000387)3.10460662
78pyrimidine ribonucleoside catabolic process (GO:0046133)3.06795789
79regulation of mitochondrial translation (GO:0070129)3.06765828
80establishment of viral latency (GO:0019043)3.05117582
81mitochondrial transport (GO:0006839)3.04045072
82positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.02910804
83transcription elongation from RNA polymerase III promoter (GO:0006385)3.01811443
84termination of RNA polymerase III transcription (GO:0006386)3.01811443
85antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.98992203
86establishment of integrated proviral latency (GO:0075713)2.98376910
87rRNA modification (GO:0000154)2.98166103
88regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.97392921
89regulation of cellular amino acid metabolic process (GO:0006521)2.96689518
90nucleobase-containing small molecule interconversion (GO:0015949)2.96561794
91DNA replication checkpoint (GO:0000076)2.96370936
92negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.94804352
93negative regulation of ligase activity (GO:0051352)2.94804352
94rRNA methylation (GO:0031167)2.92945715
95DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.92185414
96anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.91791731
97establishment of protein localization to membrane (GO:0090150)2.88811716
98mitotic recombination (GO:0006312)2.88703229
99positive regulation of cell cycle arrest (GO:0071158)2.88594625
100signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.88265695
101intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.88265695
102signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.86022814
103signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.86022814
104signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.86022814
105signal transduction involved in DNA damage checkpoint (GO:0072422)2.83867289
106signal transduction involved in DNA integrity checkpoint (GO:0072401)2.83867289
107establishment of protein localization to mitochondrial membrane (GO:0090151)2.83707519
108spliceosomal complex assembly (GO:0000245)2.83445899
109folic acid metabolic process (GO:0046655)2.83113542
110protein targeting (GO:0006605)2.80397087
111signal transduction involved in cell cycle checkpoint (GO:0072395)2.78029889
112establishment of protein localization to organelle (GO:0072594)2.77394200
113telomere maintenance via telomere lengthening (GO:0010833)2.76573655
114IMP biosynthetic process (GO:0006188)2.73246434
115chromatin remodeling at centromere (GO:0031055)2.69425835
116DNA unwinding involved in DNA replication (GO:0006268)2.68073268
117CENP-A containing nucleosome assembly (GO:0034080)2.67921024
118transcription-coupled nucleotide-excision repair (GO:0006283)2.67123960
119pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.67051949
120exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.66062147
121L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.63491666
122GDP-mannose metabolic process (GO:0019673)2.62708413
123oxidative phosphorylation (GO:0006119)2.62490695
124signal peptide processing (GO:0006465)2.61801825
125positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.61575206
126nucleotide-excision repair, DNA gap filling (GO:0006297)2.59523092
127pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.59151533
128nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.56195875
129UTP biosynthetic process (GO:0006228)2.55736263
130positive regulation of ligase activity (GO:0051351)2.52063032
131guanosine-containing compound biosynthetic process (GO:1901070)2.51726432
132antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.50792151
133respiratory electron transport chain (GO:0022904)2.50320724

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.25775602
2* MYC_18555785_ChIP-Seq_MESCs_Mouse4.36583221
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse4.13266512
4KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.51246314
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.47861693
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.31579380
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.12553517
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.10417855
9* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.92603448
10* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.92226437
11CREB1_15753290_ChIP-ChIP_HEK293T_Human2.88863119
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.82816380
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.70634205
14BP1_19119308_ChIP-ChIP_Hs578T_Human2.69171375
15NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.53325166
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.46697584
17E2F4_17652178_ChIP-ChIP_JURKAT_Human2.45194224
18XRN2_22483619_ChIP-Seq_HELA_Human2.44166547
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.42108904
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.36495945
21CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.36457997
22* VDR_23849224_ChIP-Seq_CD4+_Human2.33841258
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.17127782
24* DCP1A_22483619_ChIP-Seq_HELA_Human2.16315048
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.14397987
26FOXM1_23109430_ChIP-Seq_U2OS_Human2.10800629
27MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.08078113
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.01803570
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.99077786
30FOXP3_21729870_ChIP-Seq_TREG_Human1.97496085
31GABP_19822575_ChIP-Seq_HepG2_Human1.91034054
32TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.88471115
33* TTF2_22483619_ChIP-Seq_HELA_Human1.84176983
34ELK1_19687146_ChIP-ChIP_HELA_Human1.82544290
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.74991856
36THAP11_20581084_ChIP-Seq_MESCs_Mouse1.66181905
37SRF_21415370_ChIP-Seq_HL-1_Mouse1.63284145
38FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.58723686
39FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.58595598
40POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.58327182
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.58261333
42YY1_21170310_ChIP-Seq_MESCs_Mouse1.57459479
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.57096138
44ZFX_18555785_ChIP-Seq_MESCs_Mouse1.56979754
45HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56006317
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.53998685
47MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.53753583
48NANOG_18555785_ChIP-Seq_MESCs_Mouse1.49863148
49CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.49777764
50ERG_20887958_ChIP-Seq_HPC-7_Mouse1.48903524
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.44549041
52E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.42359246
53SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.40725843
54AR_21909140_ChIP-Seq_LNCAP_Human1.40692813
55E2F1_21310950_ChIP-Seq_MCF-7_Human1.38706113
56* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.37081178
57KDM5A_27292631_Chip-Seq_BREAST_Human1.35163511
58STAT3_1855785_ChIP-Seq_MESCs_Mouse1.30568404
59MYC_22102868_ChIP-Seq_BL_Human1.30359690
60ELK1_22589737_ChIP-Seq_MCF10A_Human1.29811093
61CIITA_25753668_ChIP-Seq_RAJI_Human1.29790273
62ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.28785901
63IRF8_22096565_ChIP-ChIP_GC-B_Human1.27174551
64HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.26005348
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.23843280
66MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.22643261
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.19126763
68SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15984041
69CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.15527042
70PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.14629673
71YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14259515
72TFEB_21752829_ChIP-Seq_HELA_Human1.11770593
73TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.11549944
74POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.10651920
75STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09764577
76SPI1_23547873_ChIP-Seq_NB4_Human1.09494714
77HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.09298514
78CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.08541673
79VDR_21846776_ChIP-Seq_THP-1_Human1.06940868
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.06242220
81PADI4_21655091_ChIP-ChIP_MCF-7_Human1.06239289
82KLF4_18555785_ChIP-Seq_MESCs_Mouse1.05012903
83POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.04215016
84EGR1_19374776_ChIP-ChIP_THP-1_Human1.03945868
85ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03372283
86* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.03166133
87TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.00996089
88IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.96064229
89* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.95915624
90GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.95671442
91IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.95258188
92KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.94906072
93KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94384359
94SRY_22984422_ChIP-ChIP_TESTIS_Rat0.93611089
95ELF5_23300383_ChIP-Seq_T47D_Human0.93307700
96HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.93195983
97MYC_18940864_ChIP-ChIP_HL60_Human0.93173961
98ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.90720552
99NOTCH1_21737748_ChIP-Seq_TLL_Human0.89518434
100IRF8_21731497_ChIP-ChIP_J774_Mouse0.89448654
101DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.89068045
102OCT4_18692474_ChIP-Seq_MEFs_Mouse0.85544856
103GATA1_22383799_ChIP-Seq_G1ME_Mouse0.84017063
104CTCF_18555785_ChIP-Seq_MESCs_Mouse0.82131791
105ERG_20517297_ChIP-Seq_VCAP_Human0.79362906
106STAT1_20625510_ChIP-Seq_HELA_Human0.78543853
107PPARA_22158963_ChIP-Seq_LIVER_Mouse0.77072809
108SOX2_18692474_ChIP-Seq_MEFs_Mouse0.76805171
109FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76495905
110MYB_26560356_Chip-Seq_TH2_Human0.74796141
111RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.74187222
112GATA3_26560356_Chip-Seq_TH2_Human0.71358901
113ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.71070640
114* PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.70886274
115EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.70467861
116VDR_22108803_ChIP-Seq_LS180_Human0.69601817
117SOX2_18555785_ChIP-Seq_MESCs_Mouse0.67842438
118* TP53_22573176_ChIP-Seq_HFKS_Human0.66765132
119NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.66110312

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.18463622
2MP0004957_abnormal_blastocyst_morpholog3.94302451
3MP0003806_abnormal_nucleotide_metabolis3.31081930
4MP0003077_abnormal_cell_cycle2.73388361
5MP0010094_abnormal_chromosome_stability2.70639202
6MP0003111_abnormal_nucleus_morphology2.65304217
7MP0009379_abnormal_foot_pigmentation2.53847712
8MP0003186_abnormal_redox_activity2.38376524
9MP0002277_abnormal_respiratory_mucosa2.26799925
10MP0008057_abnormal_DNA_replication2.25096937
11MP0001873_stomach_inflammation2.12337628
12MP0008058_abnormal_DNA_repair2.04023797
13MP0002163_abnormal_gland_morphology2.00035631
14MP0008932_abnormal_embryonic_tissue1.98554545
15MP0003011_delayed_dark_adaptation1.85971969
16MP0001790_abnormal_immune_system1.83758994
17MP0005387_immune_system_phenotype1.83758994
18MP0000490_abnormal_crypts_of1.82680974
19MP0006036_abnormal_mitochondrial_physio1.76963660
20MP0009333_abnormal_splenocyte_physiolog1.76368493
21MP0002396_abnormal_hematopoietic_system1.73152929
22MP0008007_abnormal_cellular_replicative1.72428175
23MP0006292_abnormal_olfactory_placode1.69380668
24MP0006082_CNS_inflammation1.68184296
25MP0010352_gastrointestinal_tract_polyps1.65068645
26MP0005083_abnormal_biliary_tract1.64597176
27MP0006072_abnormal_retinal_apoptosis1.63794086
28MP0000372_irregular_coat_pigmentation1.56121804
29MP0001730_embryonic_growth_arrest1.55165479
30MP0005084_abnormal_gallbladder_morpholo1.52693736
31MP0002139_abnormal_hepatobiliary_system1.47307876
32MP0003718_maternal_effect1.46971370
33MP0003786_premature_aging1.46477118
34MP0005220_abnormal_exocrine_pancreas1.43749513
35MP0000350_abnormal_cell_proliferation1.39206289
36MP0006054_spinal_hemorrhage1.34549173
37MP0005379_endocrine/exocrine_gland_phen1.32561214
38MP0005365_abnormal_bile_salt1.32512549
39MP0002138_abnormal_hepatobiliary_system1.31121723
40MP0002019_abnormal_tumor_incidence1.30947061
41MP0005085_abnormal_gallbladder_physiolo1.29261393
42MP0001919_abnormal_reproductive_system1.29174408
43MP0002837_dystrophic_cardiac_calcinosis1.28430804
44MP0005408_hypopigmentation1.28127960
45MP0003123_paternal_imprinting1.27668942
46MP0003763_abnormal_thymus_physiology1.26361542
47MP0000358_abnormal_cell_content/1.20784018
48MP0001853_heart_inflammation1.20713884
49MP0002132_abnormal_respiratory_system1.19112251
50MP0003436_decreased_susceptibility_to1.18123036
51MP0001764_abnormal_homeostasis1.17424262
52MP0005360_urolithiasis1.17335375
53MP0001835_abnormal_antigen_presentation1.17116538
54MP0000858_altered_metastatic_potential1.16230656
55MP0009840_abnormal_foam_cell1.15448188
56MP0000313_abnormal_cell_death1.15373652
57MP0001666_abnormal_nutrient_absorption1.14719115
58MP0003656_abnormal_erythrocyte_physiolo1.13887052
59MP0002938_white_spotting1.13686150
60MP0001905_abnormal_dopamine_level1.13633215
61MP0002095_abnormal_skin_pigmentation1.11432890
62MP0009764_decreased_sensitivity_to1.11234988
63MP0002080_prenatal_lethality1.11032743
64MP0009643_abnormal_urine_homeostasis1.10698113
65MP0008872_abnormal_physiological_respon1.10255484
66MP0004264_abnormal_extraembryonic_tissu1.09080103
67MP0002876_abnormal_thyroid_physiology1.07135846
68MP0005636_abnormal_mineral_homeostasis1.07121034
69MP0002722_abnormal_immune_system1.06912001
70MP0002166_altered_tumor_susceptibility1.06776471
71MP0001542_abnormal_bone_strength1.05656299
72MP0008995_early_reproductive_senescence1.05362978
73MP0006035_abnormal_mitochondrial_morpho1.05021225
74MP0001697_abnormal_embryo_size1.04895850
75MP0001727_abnormal_embryo_implantation1.04721743
76MP0003195_calcinosis1.04201861
77MP0005389_reproductive_system_phenotype1.03283187
78MP0001881_abnormal_mammary_gland1.03072900
79MP0000689_abnormal_spleen_morphology1.02364518
80MP0002398_abnormal_bone_marrow1.01745087
81MP0003567_abnormal_fetal_cardiomyocyte0.97991798
82MP0000343_altered_response_to0.95909176
83MP0004147_increased_porphyrin_level0.95236231
84MP0002429_abnormal_blood_cell0.94584852
85MP0005380_embryogenesis_phenotype0.92579526
86MP0001672_abnormal_embryogenesis/_devel0.92579526
87MP0002419_abnormal_innate_immunity0.92279777
88MP0005025_abnormal_response_to0.92039567
89MP0004142_abnormal_muscle_tone0.91407419
90MP0005501_abnormal_skin_physiology0.90819417
91MP0002693_abnormal_pancreas_physiology0.90813141
92MP0001800_abnormal_humoral_immune0.89997909
93MP0008873_increased_physiological_sensi0.89212529
94MP0000703_abnormal_thymus_morphology0.88931817
95MP0005397_hematopoietic_system_phenotyp0.87138885
96MP0001545_abnormal_hematopoietic_system0.87138885
97MP0002006_tumorigenesis0.86925198
98MP0001845_abnormal_inflammatory_respons0.86469369
99MP0008469_abnormal_protein_level0.86268230
100MP0010155_abnormal_intestine_physiology0.86178070
101MP0004808_abnormal_hematopoietic_stem0.85844504
102MP0009785_altered_susceptibility_to0.85589487
103MP0000609_abnormal_liver_physiology0.84958240
104MP0000716_abnormal_immune_system0.84735594
105MP0005319_abnormal_enzyme/_coenzyme0.84501700
106MP0010307_abnormal_tumor_latency0.84025305
107MP0003984_embryonic_growth_retardation0.83991406
108MP0005332_abnormal_amino_acid0.83767647
109MP0003866_abnormal_defecation0.83315233
110MP0000685_abnormal_immune_system0.82820233
111MP0005671_abnormal_response_to0.82453599
112MP0000750_abnormal_muscle_regeneration0.82272640
113MP0000598_abnormal_liver_morphology0.81894174
114MP0002088_abnormal_embryonic_growth/wei0.81760871
115MP0002796_impaired_skin_barrier0.81629831
116MP0003941_abnormal_skin_development0.80981931
117MP0002420_abnormal_adaptive_immunity0.79823624
118MP0005075_abnormal_melanosome_morpholog0.79568698
119MP0008877_abnormal_DNA_methylation0.78745316
120MP0002723_abnormal_immune_serum0.78611479
121MP0001819_abnormal_immune_cell0.78353805
122MP0001944_abnormal_pancreas_morphology0.77903785
123MP0002405_respiratory_system_inflammati0.77585256
124MP0002086_abnormal_extraembryonic_tissu0.77403080
125MP0005000_abnormal_immune_tolerance0.77120387
126MP0002452_abnormal_antigen_presenting0.76284291
127MP0002877_abnormal_melanocyte_morpholog0.76260357
128MP0004019_abnormal_vitamin_homeostasis0.75996699
129MP0009763_increased_sensitivity_to0.75471677
130MP0009765_abnormal_xenobiotic_induced0.74676464
131MP0000477_abnormal_intestine_morphology0.74415385
132MP0002148_abnormal_hypersensitivity_rea0.73906400
133MP0001756_abnormal_urination0.73882784
134MP0005023_abnormal_wound_healing0.73007309
135MP0008875_abnormal_xenobiotic_pharmacok0.72684241
136MP0002933_joint_inflammation0.72470771
137MP0005266_abnormal_metabolism0.71531733
138MP0003136_yellow_coat_color0.70893565
139MP0003315_abnormal_perineum_morphology0.68541462
140MP0003638_abnormal_response/metabolism_0.68394600

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)7.03032764
2Abnormal number of erythroid precursors (HP:0012131)6.42425276
3Reticulocytopenia (HP:0001896)5.88119444
4Macrocytic anemia (HP:0001972)4.75028899
5Pallor (HP:0000980)4.27902211
6Multiple enchondromatosis (HP:0005701)3.62883230
7Oral leukoplakia (HP:0002745)3.58301819
8Aplastic anemia (HP:0001915)3.55940069
9Acute necrotizing encephalopathy (HP:0006965)3.51450153
10Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.51385834
11Decreased activity of mitochondrial respiratory chain (HP:0008972)3.51385834
12Mitochondrial inheritance (HP:0001427)3.36276188
13Hepatic necrosis (HP:0002605)3.33378553
14Abnormal mitochondria in muscle tissue (HP:0008316)3.29822256
15Acute encephalopathy (HP:0006846)3.15384423
16Hepatocellular necrosis (HP:0001404)3.13523814
17Increased hepatocellular lipid droplets (HP:0006565)3.07282280
18Increased CSF lactate (HP:0002490)3.06633528
19Lipid accumulation in hepatocytes (HP:0006561)2.98825698
20Birth length less than 3rd percentile (HP:0003561)2.89486525
21Type I transferrin isoform profile (HP:0003642)2.83743172
22Thrombocytosis (HP:0001894)2.83560151
23Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.82958554
24Aplasia/Hypoplasia of the sacrum (HP:0008517)2.77910528
25Microretrognathia (HP:0000308)2.70069262
26Abnormal hemoglobin (HP:0011902)2.67431766
27Carpal bone hypoplasia (HP:0001498)2.65461227
28Progressive macrocephaly (HP:0004481)2.65362149
29Optic disc pallor (HP:0000543)2.63996361
30Trismus (HP:0000211)2.63211134
31Reduced antithrombin III activity (HP:0001976)2.62445459
32Increased serum lactate (HP:0002151)2.62161914
33Leukodystrophy (HP:0002415)2.60994503
34Cerebral edema (HP:0002181)2.60992355
35Exertional dyspnea (HP:0002875)2.60711309
36Increased intramyocellular lipid droplets (HP:0012240)2.59705796
37Rough bone trabeculation (HP:0100670)2.55281118
38IgG deficiency (HP:0004315)2.53300989
39Hypoglycemic coma (HP:0001325)2.51377149
40Breast hypoplasia (HP:0003187)2.51076263
41Abnormality of reticulocytes (HP:0004312)2.49580784
42Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.45744483
43Increased IgM level (HP:0003496)2.44962072
44Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.41150861
45Increased muscle lipid content (HP:0009058)2.40617906
46Methylmalonic acidemia (HP:0002912)2.40584028
47Methylmalonic aciduria (HP:0012120)2.37451478
48Progressive muscle weakness (HP:0003323)2.36950624
493-Methylglutaconic aciduria (HP:0003535)2.36017755
50Abnormality of aromatic amino acid family metabolism (HP:0004338)2.35527280
51Lactic acidosis (HP:0003128)2.32432365
5211 pairs of ribs (HP:0000878)2.32333801
53Renal Fanconi syndrome (HP:0001994)2.31206649
54IgM deficiency (HP:0002850)2.27779454
55Abnormal protein glycosylation (HP:0012346)2.27169927
56Abnormal glycosylation (HP:0012345)2.27169927
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.27169927
58Abnormal protein N-linked glycosylation (HP:0012347)2.27169927
59Respiratory failure (HP:0002878)2.22809184
60Exercise intolerance (HP:0003546)2.22741828
61Abnormality of the anterior horn cell (HP:0006802)2.17991825
62Degeneration of anterior horn cells (HP:0002398)2.17991825
63Elevated erythrocyte sedimentation rate (HP:0003565)2.17907545
64Abnormality of pyrimidine metabolism (HP:0004353)2.14705444
65Generalized aminoaciduria (HP:0002909)2.14194591
66Colon cancer (HP:0003003)2.11555650
67Respiratory difficulties (HP:0002880)2.09900859
68Poor head control (HP:0002421)2.07635649
69Secondary amenorrhea (HP:0000869)2.07344669
70Abnormality of placental membranes (HP:0011409)2.05999589
71Amniotic constriction ring (HP:0009775)2.05999589
72Absent thumb (HP:0009777)2.05123863
73Pancytopenia (HP:0001876)2.01945542
74Hypoplasia of the pons (HP:0012110)2.01144279
75Lethargy (HP:0001254)1.97938014
76Nausea (HP:0002018)1.96143074
77Sparse eyelashes (HP:0000653)1.95355070
78Abnormality of monocarboxylic acid metabolism (HP:0010996)1.94172367
79Abnormality of dicarboxylic acid metabolism (HP:0010995)1.93630609
80Dicarboxylic aciduria (HP:0003215)1.93630609
81Premature graying of hair (HP:0002216)1.93488921
82Abnormality of the pons (HP:0007361)1.91408716
83CNS demyelination (HP:0007305)1.89647957
84Abnormality of the heme biosynthetic pathway (HP:0010472)1.89403499
85Cleft eyelid (HP:0000625)1.89390956
86Glycosuria (HP:0003076)1.87344129
87Abnormality of urine glucose concentration (HP:0011016)1.87344129
88Abnormality of T cells (HP:0002843)1.86986153
89Abnormal trabecular bone morphology (HP:0100671)1.84836008
90Congenital ichthyosiform erythroderma (HP:0007431)1.84287780
91X-linked dominant inheritance (HP:0001423)1.83779084
92Premature ovarian failure (HP:0008209)1.83775171
93Abnormal cartilage morphology (HP:0002763)1.83536082
94Neutropenia (HP:0001875)1.83239077
95Abnormality of aspartate family amino acid metabolism (HP:0010899)1.82929821
96Abnormality of T cell number (HP:0011839)1.80376952
97Cellular immunodeficiency (HP:0005374)1.79240407
98Abnormality of T cell physiology (HP:0011840)1.79002422
99Cerebral hypomyelination (HP:0006808)1.78652210
100Hyperphosphaturia (HP:0003109)1.78409673
101Abnormality of methionine metabolism (HP:0010901)1.78158306
102Selective tooth agenesis (HP:0001592)1.77851635
103Stenosis of the external auditory canal (HP:0000402)1.77774318
104Depressed nasal ridge (HP:0000457)1.77364002
105Decreased electroretinogram (ERG) amplitude (HP:0000654)1.76725983
106Glossoptosis (HP:0000162)1.73973412
107Abnormality of the intrinsic pathway (HP:0010989)1.73418855
108Petechiae (HP:0000967)1.73308377
109Microvesicular hepatic steatosis (HP:0001414)1.72966338
110Autoimmune hemolytic anemia (HP:0001890)1.72870280
111Stomatitis (HP:0010280)1.71979767
112Testicular atrophy (HP:0000029)1.71483338
113Aplasia/hypoplasia of the uterus (HP:0008684)1.70792685
114Congenital, generalized hypertrichosis (HP:0004540)1.70758091
115Hypobetalipoproteinemia (HP:0003563)1.69722596
116Megaloblastic anemia (HP:0001889)1.65271776
117Hypoplasia of the radius (HP:0002984)1.64833732
118Abnormal urine phosphate concentration (HP:0012599)1.64279984
119Neoplasm of the pancreas (HP:0002894)1.64184498
120Parakeratosis (HP:0001036)1.63122711
121Emotional lability (HP:0000712)1.62583176
122Abnormality of serum amino acid levels (HP:0003112)1.62015280
123Late onset (HP:0003584)1.61671257
124Vomiting (HP:0002013)1.60394092
125Increased serum ferritin (HP:0003281)1.60162046
126T lymphocytopenia (HP:0005403)1.59989493
127Abnormality of the prostate (HP:0008775)1.59366938
128Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.58445199
129Pancreatic cysts (HP:0001737)1.58032486
130Blindness (HP:0000618)1.55356208
131Vacuolated lymphocytes (HP:0001922)1.55347782
132Horseshoe kidney (HP:0000085)1.55333222
133Abnormal delayed hypersensitivity skin test (HP:0002963)1.55196090
134Bone marrow hypocellularity (HP:0005528)1.54405337
135Increased serum pyruvate (HP:0003542)1.54377282
136Renal tubular dysfunction (HP:0000124)1.53112672
137Abnormality of renal resorption (HP:0011038)1.49622730

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK25.59445826
2NME25.16274345
3BUB13.52668157
4WEE13.21888694
5EIF2AK32.93428341
6TXK2.91256644
7EIF2AK12.89014818
8STK162.76355917
9MAP3K122.46800654
10BCKDK2.29286977
11TESK22.12560458
12PIM22.10873332
13CDC72.07055867
14VRK12.02526213
15RPS6KB22.00509089
16SRPK11.96912167
17PASK1.95080374
18NUAK11.78408981
19SCYL21.77412047
20BRSK21.76042752
21ERN11.75277076
22TLK11.70668906
23LRRK21.70559607
24ACVR1B1.63686080
25PLK41.62994856
26MST41.59442096
27FLT31.58827991
28TAF11.55244130
29EPHA21.52366931
30DYRK31.50406913
31NEK21.45732220
32KDR1.44450948
33RPS6KA41.44299294
34TESK11.42276232
35MAPKAPK31.42064273
36AURKB1.37941533
37NME11.34064314
38IRAK31.27050763
39TSSK61.21745321
40CDK191.21669426
41MAP4K11.19881192
42PLK11.18485029
43CDK71.16845750
44MYLK1.15613977
45MAP3K81.12096395
46GRK71.09291248
47TEC1.07563920
48EEF2K1.06559757
49MAP3K111.05729824
50NEK11.03656322
51ADRBK21.03274094
52TTK1.02933654
53AURKA1.02808677
54PIK3CG1.00473071
55PAK40.97740521
56STK100.97469362
57GRK10.95303534
58DYRK20.92471949
59ATR0.90374695
60ILK0.89523644
61PDK20.88626482
62MARK30.88426317
63BMPR1B0.86510692
64PKN20.86078390
65TYK20.83827616
66CDK40.83550567
67ABL20.82635775
68PIM10.82074721
69IKBKE0.80431467
70BRAF0.80381991
71ZAP700.80086927
72PBK0.79079907
73CSNK2A20.78821530
74BTK0.77734767
75MAP3K30.77333670
76DAPK10.77210762
77TGFBR10.77207519
78MAP2K20.76069761
79MAP4K20.74731788
80TAOK30.74559660
81CSNK2A10.73247885
82BRSK10.70650349
83GRK60.70637790
84BMPR20.70388834
85PIK3CA0.68852261
86MAP2K30.67246520
87IRAK40.65985766
88PRKCI0.64834869
89PAK10.64748311
90STK40.63674478
91ARAF0.62342974
92ITK0.61894991
93CHEK20.61815743
94EIF2AK20.60015281
95LIMK10.59557408
96RPS6KA50.58994456
97ZAK0.58455913
98PRKCQ0.58253056
99CAMKK20.58216381
100MKNK10.57877952
101CCNB10.57872922
102BLK0.54254512
103PLK30.53452069
104CHEK10.53305180
105MAP3K100.53135714
106MST1R0.51913917
107MUSK0.48452910
108CDK80.48093091
109TBK10.47377791
110IKBKB0.45896595
111OXSR10.45823091
112GRK50.45550215
113LCK0.44199577
114MOS0.42396482
115JAK30.41764455
116INSRR0.40240357
117LYN0.38552421
118TAOK20.38185454
119SYK0.34741822
120CLK10.34471524
121RAF10.33849072
122CSK0.33618488
123CDK20.32864788
124PRKCD0.32468240
125ATM0.32276492
126ADRBK10.31766868
127NEK90.31560175
128NLK0.31322353
129KIT0.31130296
130WNK40.28800136
131CDK60.28499251
132MAP2K60.28236622
133MATK0.27506590
134FES0.27352695
135MAPKAPK20.26269075
136CSF1R0.26163947
137DAPK30.25180583
138MKNK20.22764171
139MAPK110.22207605

Predicted pathways (KEGG)

RankGene SetZ-score
1* Ribosome_Homo sapiens_hsa030105.68057406
2Proteasome_Homo sapiens_hsa030503.68276128
3DNA replication_Homo sapiens_hsa030303.60969880
4Protein export_Homo sapiens_hsa030603.05080107
5RNA polymerase_Homo sapiens_hsa030202.99376684
6Mismatch repair_Homo sapiens_hsa034302.84154418
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.53464263
8Pyrimidine metabolism_Homo sapiens_hsa002402.43263722
9Spliceosome_Homo sapiens_hsa030402.40776799
10Oxidative phosphorylation_Homo sapiens_hsa001902.22260623
11Homologous recombination_Homo sapiens_hsa034402.10631181
12One carbon pool by folate_Homo sapiens_hsa006702.09100751
13Parkinsons disease_Homo sapiens_hsa050122.06377320
14Nucleotide excision repair_Homo sapiens_hsa034202.03757193
15RNA transport_Homo sapiens_hsa030131.97397565
16Base excision repair_Homo sapiens_hsa034101.93912318
17Folate biosynthesis_Homo sapiens_hsa007901.89003569
18Cardiac muscle contraction_Homo sapiens_hsa042601.84402955
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.82098949
20Allograft rejection_Homo sapiens_hsa053301.75960337
21Autoimmune thyroid disease_Homo sapiens_hsa053201.71998582
22Asthma_Homo sapiens_hsa053101.61473398
23Graft-versus-host disease_Homo sapiens_hsa053321.58593931
24Huntingtons disease_Homo sapiens_hsa050161.55256125
25Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.49867013
26Sulfur relay system_Homo sapiens_hsa041221.43497066
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.38844085
28Drug metabolism - other enzymes_Homo sapiens_hsa009831.30780448
29Type I diabetes mellitus_Homo sapiens_hsa049401.30115648
30Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.29878764
31Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.28892798
32Cell cycle_Homo sapiens_hsa041101.25071686
33Non-homologous end-joining_Homo sapiens_hsa034501.24926149
34Alzheimers disease_Homo sapiens_hsa050101.24244104
35RNA degradation_Homo sapiens_hsa030181.21898450
36Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.21042692
37Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.19356879
38Selenocompound metabolism_Homo sapiens_hsa004501.17684316
39Pentose phosphate pathway_Homo sapiens_hsa000301.16693336
40Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.12081620
41Fanconi anemia pathway_Homo sapiens_hsa034601.11863921
42Purine metabolism_Homo sapiens_hsa002301.09164134
43Basal transcription factors_Homo sapiens_hsa030221.05485053
44Glutathione metabolism_Homo sapiens_hsa004801.04291967
45Rheumatoid arthritis_Homo sapiens_hsa053231.02294472
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.01024060
47Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.00447588
48p53 signaling pathway_Homo sapiens_hsa041150.95420108
49N-Glycan biosynthesis_Homo sapiens_hsa005100.92713112
50Antigen processing and presentation_Homo sapiens_hsa046120.91100045
51Cyanoamino acid metabolism_Homo sapiens_hsa004600.89252188
52Sulfur metabolism_Homo sapiens_hsa009200.88992846
53Systemic lupus erythematosus_Homo sapiens_hsa053220.86160987
54Biosynthesis of amino acids_Homo sapiens_hsa012300.84524520
55Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.84063737
56Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.82990216
57Carbon metabolism_Homo sapiens_hsa012000.81903615
58Epstein-Barr virus infection_Homo sapiens_hsa051690.76442976
59Collecting duct acid secretion_Homo sapiens_hsa049660.74751617
60Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.74317479
61Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73842227
62SNARE interactions in vesicular transport_Homo sapiens_hsa041300.70880667
63Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.69061045
64Metabolic pathways_Homo sapiens_hsa011000.66427430
65Pentose and glucuronate interconversions_Homo sapiens_hsa000400.65024971
66Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.64612456
67Tyrosine metabolism_Homo sapiens_hsa003500.64463633
68Phenylalanine metabolism_Homo sapiens_hsa003600.63758595
69Legionellosis_Homo sapiens_hsa051340.62428920
70Galactose metabolism_Homo sapiens_hsa000520.61809862
712-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.57966606
72Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.56529207
73Other glycan degradation_Homo sapiens_hsa005110.54948892
74Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.53460615
75Fat digestion and absorption_Homo sapiens_hsa049750.53264805
76Pyruvate metabolism_Homo sapiens_hsa006200.52429092
77Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.51349369
78Arginine and proline metabolism_Homo sapiens_hsa003300.50237072
79Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.49992883
80Herpes simplex infection_Homo sapiens_hsa051680.49910131
81Chemical carcinogenesis_Homo sapiens_hsa052040.49880727
82NF-kappa B signaling pathway_Homo sapiens_hsa040640.49714475
83Fructose and mannose metabolism_Homo sapiens_hsa000510.48600175
84Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47465611
85mRNA surveillance pathway_Homo sapiens_hsa030150.47331444
86Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.46897058
87Primary immunodeficiency_Homo sapiens_hsa053400.46354849
88Peroxisome_Homo sapiens_hsa041460.43546652
89Thyroid cancer_Homo sapiens_hsa052160.42819118
90Caffeine metabolism_Homo sapiens_hsa002320.42630891
91Histidine metabolism_Homo sapiens_hsa003400.42342820
92Tryptophan metabolism_Homo sapiens_hsa003800.42078859
93Viral myocarditis_Homo sapiens_hsa054160.40733352
94Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40710893
95Renin-angiotensin system_Homo sapiens_hsa046140.39688019
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39035419
97Viral carcinogenesis_Homo sapiens_hsa052030.38887703
98Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.38540776
99Linoleic acid metabolism_Homo sapiens_hsa005910.36505325
100Mineral absorption_Homo sapiens_hsa049780.35193256
101Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.33988546
102Vitamin digestion and absorption_Homo sapiens_hsa049770.33926301
103Arachidonic acid metabolism_Homo sapiens_hsa005900.33552972
104Primary bile acid biosynthesis_Homo sapiens_hsa001200.32531935
105Fatty acid degradation_Homo sapiens_hsa000710.32523981
106beta-Alanine metabolism_Homo sapiens_hsa004100.31308374
107Propanoate metabolism_Homo sapiens_hsa006400.28779454
108Intestinal immune network for IgA production_Homo sapiens_hsa046720.27621914
109Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.24782010
110Measles_Homo sapiens_hsa051620.24778726
111NOD-like receptor signaling pathway_Homo sapiens_hsa046210.24110612
112Regulation of autophagy_Homo sapiens_hsa041400.23584364
113Apoptosis_Homo sapiens_hsa042100.22240454
114Vitamin B6 metabolism_Homo sapiens_hsa007500.22022713
115alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.21183463
116Phototransduction_Homo sapiens_hsa047440.20757448
117Staphylococcus aureus infection_Homo sapiens_hsa051500.20722752
118Hematopoietic cell lineage_Homo sapiens_hsa046400.19674808
119Butanoate metabolism_Homo sapiens_hsa006500.18613457
120RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.18481346
121Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.17698520
122Starch and sucrose metabolism_Homo sapiens_hsa005000.17335643
123Retinol metabolism_Homo sapiens_hsa008300.16930122
124Glycosaminoglycan degradation_Homo sapiens_hsa005310.16696737
125Steroid hormone biosynthesis_Homo sapiens_hsa001400.16561342
126Fatty acid elongation_Homo sapiens_hsa000620.16549042
127Leishmaniasis_Homo sapiens_hsa051400.16018504

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