

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 9.92609440 |
| 2 | DNA deamination (GO:0045006) | 9.88219218 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 9.59508148 |
| 4 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.32929500 |
| 5 | negative regulation by host of viral transcription (GO:0043922) | 5.12726559 |
| 6 | eosinophil chemotaxis (GO:0048245) | 5.07024701 |
| 7 | negative regulation of T cell apoptotic process (GO:0070233) | 4.99439595 |
| 8 | pyrimidine nucleoside catabolic process (GO:0046135) | 4.91837911 |
| 9 | positive regulation of interleukin-8 secretion (GO:2000484) | 4.88314020 |
| 10 | sequestering of actin monomers (GO:0042989) | 4.83864326 |
| 11 | actin nucleation (GO:0045010) | 4.82494419 |
| 12 | positive T cell selection (GO:0043368) | 4.76464500 |
| 13 | eosinophil migration (GO:0072677) | 4.60062807 |
| 14 | regulation of regulatory T cell differentiation (GO:0045589) | 4.58812323 |
| 15 | regulation of activation of Janus kinase activity (GO:0010533) | 4.48304325 |
| 16 | positive thymic T cell selection (GO:0045059) | 4.48051053 |
| 17 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 4.37978980 |
| 18 | cytolysis (GO:0019835) | 4.35190019 |
| 19 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 4.32881541 |
| 20 | negative regulation of viral genome replication (GO:0045071) | 4.28147015 |
| 21 | protein neddylation (GO:0045116) | 4.14136472 |
| 22 | positive regulation of B cell differentiation (GO:0045579) | 4.13601683 |
| 23 | macrophage chemotaxis (GO:0048246) | 4.03286832 |
| 24 | positive regulation of tolerance induction (GO:0002645) | 3.95632535 |
| 25 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.95116857 |
| 26 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.93242587 |
| 27 | regulation of T cell tolerance induction (GO:0002664) | 3.89442475 |
| 28 | T cell migration (GO:0072678) | 3.86846107 |
| 29 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.86251724 |
| 30 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.81834183 |
| 31 | cellular response to interleukin-15 (GO:0071350) | 3.81707022 |
| 32 | regulation of chronic inflammatory response (GO:0002676) | 3.81667210 |
| 33 | regulation of lymphocyte chemotaxis (GO:1901623) | 3.79418926 |
| 34 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.77148465 |
| 35 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.71331535 |
| 36 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.71331535 |
| 37 | regulation of interleukin-8 secretion (GO:2000482) | 3.70178677 |
| 38 | negative T cell selection (GO:0043383) | 3.62028045 |
| 39 | negative regulation of lymphocyte apoptotic process (GO:0070229) | 3.58415238 |
| 40 | ATP synthesis coupled proton transport (GO:0015986) | 3.55075848 |
| 41 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.55075848 |
| 42 | respiratory electron transport chain (GO:0022904) | 3.46614622 |
| 43 | positive regulation of lymphocyte migration (GO:2000403) | 3.44674873 |
| 44 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.44534373 |
| 45 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.43825338 |
| 46 | positive regulation of cell killing (GO:0031343) | 3.42733413 |
| 47 | positive regulation of T cell chemotaxis (GO:0010820) | 3.42293568 |
| 48 | regulation of T cell chemotaxis (GO:0010819) | 3.42293568 |
| 49 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.42250873 |
| 50 | electron transport chain (GO:0022900) | 3.39226112 |
| 51 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.35446119 |
| 52 | regulation of B cell differentiation (GO:0045577) | 3.35243685 |
| 53 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.35215191 |
| 54 | iron-sulfur cluster assembly (GO:0016226) | 3.32160841 |
| 55 | metallo-sulfur cluster assembly (GO:0031163) | 3.32160841 |
| 56 | thymic T cell selection (GO:0045061) | 3.29098835 |
| 57 | DNA demethylation (GO:0080111) | 3.28717537 |
| 58 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.27738998 |
| 59 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.27122426 |
| 60 | regulation of T cell apoptotic process (GO:0070232) | 3.25868104 |
| 61 | positive regulation of T cell apoptotic process (GO:0070234) | 3.25732695 |
| 62 | pyrimidine-containing compound catabolic process (GO:0072529) | 3.25330925 |
| 63 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.25112569 |
| 64 | T cell receptor signaling pathway (GO:0050852) | 3.21584854 |
| 65 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.21437208 |
| 66 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.16005996 |
| 67 | T cell costimulation (GO:0031295) | 3.15908531 |
| 68 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.13428494 |
| 69 | lymphocyte costimulation (GO:0031294) | 3.12191904 |
| 70 | proteasome assembly (GO:0043248) | 3.12150669 |
| 71 | regulation of tolerance induction (GO:0002643) | 3.09699172 |
| 72 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.09615051 |
| 73 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.09615051 |
| 74 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.09598131 |
| 75 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.06597932 |
| 76 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.06597932 |
| 77 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.06597932 |
| 78 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.06553386 |
| 79 | regulation of cell killing (GO:0031341) | 3.06269608 |
| 80 | regulation of viral genome replication (GO:0045069) | 3.06010601 |
| 81 | positive regulation of translational initiation (GO:0045948) | 3.03769867 |
| 82 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.03748028 |
| 83 | T cell selection (GO:0045058) | 3.03398760 |
| 84 | monocyte chemotaxis (GO:0002548) | 3.00065438 |
| 85 | positive regulation of defense response to virus by host (GO:0002230) | 2.96731701 |
| 86 | negative regulation of B cell proliferation (GO:0030889) | 2.96354170 |
| 87 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.96066735 |
| 88 | ribosomal small subunit assembly (GO:0000028) | 2.95041235 |
| 89 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.94519442 |
| 90 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.92418390 |
| 91 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.91465617 |
| 92 | response to interleukin-15 (GO:0070672) | 2.90467908 |
| 93 | regulation of chemokine-mediated signaling pathway (GO:0070099) | 2.90405795 |
| 94 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.90053812 |
| 95 | negative regulation of ligase activity (GO:0051352) | 2.90053812 |
| 96 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.89511367 |
| 97 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.89511367 |
| 98 | cytidine deamination (GO:0009972) | 11.1676164 |
| 99 | cytidine metabolic process (GO:0046087) | 11.1676164 |
| 100 | cytidine catabolic process (GO:0006216) | 11.1676164 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 8.07030028 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.04247705 |
| 3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.81286683 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.57875050 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.50002290 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.02071261 |
| 7 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.86795804 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.80463531 |
| 9 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.75344231 |
| 10 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.60447281 |
| 11 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.44881978 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.42516283 |
| 13 | MYB_26560356_Chip-Seq_TH2_Human | 2.34725369 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.32519981 |
| 15 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.28067080 |
| 16 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.26164002 |
| 17 | VDR_22108803_ChIP-Seq_LS180_Human | 2.15826031 |
| 18 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.09643157 |
| 19 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.05084862 |
| 20 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.05004147 |
| 21 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.98804109 |
| 22 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.85557534 |
| 23 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83971470 |
| 24 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.81137729 |
| 25 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.79594146 |
| 26 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.78375614 |
| 27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.78230229 |
| 28 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.77103200 |
| 29 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.71055016 |
| 30 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.70875923 |
| 31 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.64877950 |
| 32 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.58581974 |
| 33 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.58294358 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.57325850 |
| 35 | GATA3_26560356_Chip-Seq_TH2_Human | 1.50012816 |
| 36 | MYB_26560356_Chip-Seq_TH1_Human | 1.47744670 |
| 37 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.46347769 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.43307229 |
| 39 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.42596875 |
| 40 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.41070629 |
| 41 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.35771773 |
| 42 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.34603640 |
| 43 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.31642969 |
| 44 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.28053336 |
| 45 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.23994244 |
| 46 | MAF_26560356_Chip-Seq_TH2_Human | 1.22455811 |
| 47 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.21907710 |
| 48 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20918651 |
| 49 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20908578 |
| 50 | UTX_26944678_Chip-Seq_JUKART_Human | 1.20548084 |
| 51 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.19173789 |
| 52 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.18945691 |
| 53 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.18899985 |
| 54 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.17607678 |
| 55 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.15792994 |
| 56 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.14007728 |
| 57 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.13622770 |
| 58 | AR_20517297_ChIP-Seq_VCAP_Human | 1.13399486 |
| 59 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.11925143 |
| 60 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.11683990 |
| 61 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.11196916 |
| 62 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.11192658 |
| 63 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.06416274 |
| 64 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.06327531 |
| 65 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.04925158 |
| 66 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.04925158 |
| 67 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.04794698 |
| 68 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.02112113 |
| 69 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.01546164 |
| 70 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.01202469 |
| 71 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.01072466 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.98737500 |
| 73 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.98569524 |
| 74 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97168054 |
| 75 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.96538818 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95403791 |
| 77 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.95217955 |
| 78 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.94294640 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.94294640 |
| 80 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.93552428 |
| 81 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.93218512 |
| 82 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.92325939 |
| 83 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.92185815 |
| 84 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.91782707 |
| 85 | MAF_26560356_Chip-Seq_TH1_Human | 0.91768553 |
| 86 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.91656987 |
| 87 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.91200694 |
| 88 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.90484914 |
| 89 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.90086538 |
| 90 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.90063766 |
| 91 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.89423523 |
| 92 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.89380305 |
| 93 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.89063450 |
| 94 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87779833 |
| 95 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.87678997 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.87336475 |
| 97 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.87249075 |
| 98 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.86638043 |
| 99 | ERA_21632823_ChIP-Seq_H3396_Human | 0.85828370 |
| 100 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.85488031 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.37416897 |
| 2 | MP0009785_altered_susceptibility_to | 3.71050824 |
| 3 | MP0009333_abnormal_splenocyte_physiolog | 3.27293596 |
| 4 | MP0003763_abnormal_thymus_physiology | 3.15304089 |
| 5 | MP0001835_abnormal_antigen_presentation | 2.84152225 |
| 6 | MP0001873_stomach_inflammation | 2.73494884 |
| 7 | MP0006082_CNS_inflammation | 2.51475644 |
| 8 | MP0005000_abnormal_immune_tolerance | 2.50917345 |
| 9 | MP0002163_abnormal_gland_morphology | 2.30007717 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.27520856 |
| 11 | MP0005025_abnormal_response_to | 2.24465914 |
| 12 | MP0001800_abnormal_humoral_immune | 2.19822315 |
| 13 | MP0002420_abnormal_adaptive_immunity | 2.13982534 |
| 14 | MP0003866_abnormal_defecation | 2.12276791 |
| 15 | MP0002723_abnormal_immune_serum | 2.03527346 |
| 16 | MP0001819_abnormal_immune_cell | 2.03494918 |
| 17 | MP0002102_abnormal_ear_morphology | 2.00851094 |
| 18 | MP0001919_abnormal_reproductive_system | 1.97920734 |
| 19 | MP0002166_altered_tumor_susceptibility | 1.89839102 |
| 20 | MP0001790_abnormal_immune_system | 1.86868627 |
| 21 | MP0005387_immune_system_phenotype | 1.86868627 |
| 22 | MP0002933_joint_inflammation | 1.79245081 |
| 23 | MP0005645_abnormal_hypothalamus_physiol | 1.77610294 |
| 24 | MP0003646_muscle_fatigue | 1.69872224 |
| 25 | MP0000716_abnormal_immune_system | 1.64343329 |
| 26 | MP0002452_abnormal_antigen_presenting | 1.56409033 |
| 27 | MP0002405_respiratory_system_inflammati | 1.56247801 |
| 28 | MP0005379_endocrine/exocrine_gland_phen | 1.56221144 |
| 29 | MP0000703_abnormal_thymus_morphology | 1.55961089 |
| 30 | MP0002398_abnormal_bone_marrow | 1.55271176 |
| 31 | MP0010155_abnormal_intestine_physiology | 1.54614901 |
| 32 | MP0009379_abnormal_foot_pigmentation | 1.53116855 |
| 33 | MP0002006_tumorigenesis | 1.50938460 |
| 34 | MP0004145_abnormal_muscle_electrophysio | 1.49515943 |
| 35 | MP0005083_abnormal_biliary_tract | 1.48136888 |
| 36 | MP0005377_hearing/vestibular/ear_phenot | 1.47349362 |
| 37 | MP0003878_abnormal_ear_physiology | 1.47349362 |
| 38 | MP0004147_increased_porphyrin_level | 1.46944561 |
| 39 | MP0005389_reproductive_system_phenotype | 1.45821790 |
| 40 | MP0002722_abnormal_immune_system | 1.41681334 |
| 41 | MP0000685_abnormal_immune_system | 1.41257136 |
| 42 | MP0003011_delayed_dark_adaptation | 1.40148454 |
| 43 | MP0003448_altered_tumor_morphology | 1.40057362 |
| 44 | MP0003786_premature_aging | 1.36532723 |
| 45 | MP0001188_hyperpigmentation | 1.35786362 |
| 46 | MP0001845_abnormal_inflammatory_respons | 1.33911481 |
| 47 | MP0000689_abnormal_spleen_morphology | 1.33871645 |
| 48 | MP0001853_heart_inflammation | 1.33726874 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 1.27031581 |
| 50 | MP0003880_abnormal_central_pattern | 1.22466518 |
| 51 | MP0003137_abnormal_impulse_conducting | 1.22197803 |
| 52 | MP0001905_abnormal_dopamine_level | 1.21759480 |
| 53 | MP0008872_abnormal_physiological_respon | 1.21443714 |
| 54 | MP0000372_irregular_coat_pigmentation | 1.19348882 |
| 55 | MP0002429_abnormal_blood_cell | 1.18884013 |
| 56 | MP0001485_abnormal_pinna_reflex | 1.13090004 |
| 57 | MP0006072_abnormal_retinal_apoptosis | 1.12584834 |
| 58 | MP0009763_increased_sensitivity_to | 1.10784631 |
| 59 | MP0005646_abnormal_pituitary_gland | 1.09316469 |
| 60 | MP0002736_abnormal_nociception_after | 1.09245039 |
| 61 | MP0005551_abnormal_eye_electrophysiolog | 1.09154637 |
| 62 | MP0002837_dystrophic_cardiac_calcinosis | 1.08439205 |
| 63 | MP0002876_abnormal_thyroid_physiology | 1.04385031 |
| 64 | MP0001968_abnormal_touch/_nociception | 1.04256128 |
| 65 | MP0003436_decreased_susceptibility_to | 1.02662921 |
| 66 | MP0002419_abnormal_innate_immunity | 1.02001000 |
| 67 | MP0002693_abnormal_pancreas_physiology | 0.97500243 |
| 68 | MP0008995_early_reproductive_senescence | 0.96291995 |
| 69 | MP0005075_abnormal_melanosome_morpholog | 0.95685018 |
| 70 | MP0008469_abnormal_protein_level | 0.93219700 |
| 71 | MP0006276_abnormal_autonomic_nervous | 0.92425214 |
| 72 | MP0009764_decreased_sensitivity_to | 0.92134999 |
| 73 | MP0002160_abnormal_reproductive_system | 0.92052956 |
| 74 | MP0005084_abnormal_gallbladder_morpholo | 0.89668953 |
| 75 | MP0001984_abnormal_olfaction | 0.89577352 |
| 76 | MP0005253_abnormal_eye_physiology | 0.88767872 |
| 77 | MP0002138_abnormal_hepatobiliary_system | 0.86392275 |
| 78 | MP0008877_abnormal_DNA_methylation | 0.84370357 |
| 79 | MP0003195_calcinosis | 0.83894371 |
| 80 | MP0003045_fibrosis | 0.83036941 |
| 81 | MP0010386_abnormal_urinary_bladder | 0.78987798 |
| 82 | MP0002638_abnormal_pupillary_reflex | 0.78314774 |
| 83 | MP0008875_abnormal_xenobiotic_pharmacok | 0.78236852 |
| 84 | MP0003567_abnormal_fetal_cardiomyocyte | 0.78045611 |
| 85 | MP0009765_abnormal_xenobiotic_induced | 0.77562612 |
| 86 | MP0006036_abnormal_mitochondrial_physio | 0.75955511 |
| 87 | MP0005310_abnormal_salivary_gland | 0.75769735 |
| 88 | MP0002095_abnormal_skin_pigmentation | 0.75091071 |
| 89 | MP0005636_abnormal_mineral_homeostasis | 0.75066572 |
| 90 | MP0001661_extended_life_span | 0.73361476 |
| 91 | MP0004885_abnormal_endolymph | 0.72844621 |
| 92 | MP0009745_abnormal_behavioral_response | 0.72449858 |
| 93 | MP0001348_abnormal_lacrimal_gland | 0.72275204 |
| 94 | MP0001542_abnormal_bone_strength | 0.71357029 |
| 95 | MP0008873_increased_physiological_sensi | 0.71040884 |
| 96 | MP0005464_abnormal_platelet_physiology | 0.70647636 |
| 97 | MP0002019_abnormal_tumor_incidence | 0.70293982 |
| 98 | MP0008789_abnormal_olfactory_epithelium | 0.69706775 |
| 99 | MP0005410_abnormal_fertilization | 0.68578481 |
| 100 | MP0001119_abnormal_female_reproductive | 0.68347331 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Aplastic anemia (HP:0001915) | 6.45453087 |
| 2 | T lymphocytopenia (HP:0005403) | 5.40330615 |
| 3 | Abnormality of T cell number (HP:0011839) | 5.32237332 |
| 4 | Hypoproteinemia (HP:0003075) | 4.41769483 |
| 5 | Autoimmune hemolytic anemia (HP:0001890) | 4.39676577 |
| 6 | IgG deficiency (HP:0004315) | 4.31882934 |
| 7 | Increased IgM level (HP:0003496) | 4.16144999 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 4.06823693 |
| 9 | Mitochondrial inheritance (HP:0001427) | 3.97399704 |
| 10 | Severe combined immunodeficiency (HP:0004430) | 3.91594574 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.81549504 |
| 12 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.80632155 |
| 13 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.74242932 |
| 14 | Abnormality of T cells (HP:0002843) | 3.59251198 |
| 15 | Increased intramyocellular lipid droplets (HP:0012240) | 3.56584196 |
| 16 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.48795608 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.34326476 |
| 18 | Abnormality of eosinophils (HP:0001879) | 3.28080816 |
| 19 | Acute encephalopathy (HP:0006846) | 3.24616106 |
| 20 | Increased CSF lactate (HP:0002490) | 3.22953912 |
| 21 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.22553138 |
| 22 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.22553138 |
| 23 | Thyroiditis (HP:0100646) | 3.17636759 |
| 24 | Hepatocellular necrosis (HP:0001404) | 3.11876240 |
| 25 | Cerebral edema (HP:0002181) | 3.04893087 |
| 26 | Combined immunodeficiency (HP:0005387) | 3.03629097 |
| 27 | Abnormality of the prostate (HP:0008775) | 3.01697961 |
| 28 | Increased hepatocellular lipid droplets (HP:0006565) | 3.00820992 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.94598414 |
| 30 | Chronic diarrhea (HP:0002028) | 2.79697642 |
| 31 | Abnormality of B cell number (HP:0010975) | 2.77158436 |
| 32 | Eosinophilia (HP:0001880) | 2.74936532 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.74264445 |
| 34 | Abnormal albumin level (HP:0012116) | 2.72556213 |
| 35 | Hypoalbuminemia (HP:0003073) | 2.72556213 |
| 36 | Encephalitis (HP:0002383) | 2.71626742 |
| 37 | Hepatic necrosis (HP:0002605) | 2.70978314 |
| 38 | Renal Fanconi syndrome (HP:0001994) | 2.67599709 |
| 39 | Lipid accumulation in hepatocytes (HP:0006561) | 2.64305367 |
| 40 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.64070831 |
| 41 | Lymphopenia (HP:0001888) | 2.61159297 |
| 42 | Stomatitis (HP:0010280) | 2.55278225 |
| 43 | Pancreatic cysts (HP:0001737) | 2.54994564 |
| 44 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.53304419 |
| 45 | Autoimmune thrombocytopenia (HP:0001973) | 2.52432601 |
| 46 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.50712097 |
| 47 | Pancytopenia (HP:0001876) | 2.45272871 |
| 48 | Amyotrophic lateral sclerosis (HP:0007354) | 2.39341843 |
| 49 | Ureteral stenosis (HP:0000071) | 2.38878892 |
| 50 | Optic disc pallor (HP:0000543) | 2.36412341 |
| 51 | Leukocytosis (HP:0001974) | 2.34238647 |
| 52 | Hypoplasia of the thymus (HP:0000778) | 2.29878071 |
| 53 | Chronic obstructive pulmonary disease (HP:0006510) | 2.29525555 |
| 54 | Obstructive lung disease (HP:0006536) | 2.29525555 |
| 55 | Abnormality of macrophages (HP:0004311) | 2.28582849 |
| 56 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.25227696 |
| 57 | Attenuation of retinal blood vessels (HP:0007843) | 2.24858977 |
| 58 | Gangrene (HP:0100758) | 2.21124914 |
| 59 | Meningitis (HP:0001287) | 2.20462890 |
| 60 | B lymphocytopenia (HP:0010976) | 2.18005406 |
| 61 | Lactic acidosis (HP:0003128) | 2.16573174 |
| 62 | True hermaphroditism (HP:0010459) | 2.16365691 |
| 63 | Recurrent bronchitis (HP:0002837) | 2.16230627 |
| 64 | Joint swelling (HP:0001386) | 2.15301786 |
| 65 | Ureteral obstruction (HP:0006000) | 2.14346983 |
| 66 | Lethargy (HP:0001254) | 2.12054609 |
| 67 | Severe visual impairment (HP:0001141) | 2.09064762 |
| 68 | Hemiplegia (HP:0002301) | 2.08281000 |
| 69 | Increased serum lactate (HP:0002151) | 2.07908908 |
| 70 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.05108046 |
| 71 | Decreased central vision (HP:0007663) | 2.04333694 |
| 72 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.04171265 |
| 73 | Recurrent cutaneous fungal infections (HP:0011370) | 2.04171265 |
| 74 | Pancreatic fibrosis (HP:0100732) | 2.02046960 |
| 75 | Renal cortical cysts (HP:0000803) | 2.01902618 |
| 76 | Granulocytopenia (HP:0001913) | 2.00973690 |
| 77 | Oral leukoplakia (HP:0002745) | 1.99564295 |
| 78 | Exercise intolerance (HP:0003546) | 1.99080910 |
| 79 | Molar tooth sign on MRI (HP:0002419) | 1.96382244 |
| 80 | Abnormality of midbrain morphology (HP:0002418) | 1.96382244 |
| 81 | Hypergammaglobulinemia (HP:0010702) | 1.96004744 |
| 82 | Recurrent otitis media (HP:0000403) | 1.93477752 |
| 83 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.93079582 |
| 84 | Exertional dyspnea (HP:0002875) | 1.91666175 |
| 85 | Pulmonary infiltrates (HP:0002113) | 1.90107877 |
| 86 | Respiratory failure (HP:0002878) | 1.89083937 |
| 87 | Lymphoma (HP:0002665) | 1.87151890 |
| 88 | Carpal bone hypoplasia (HP:0001498) | 1.86323940 |
| 89 | Gastrointestinal infarctions (HP:0005244) | 1.84753560 |
| 90 | Chest pain (HP:0100749) | 1.83278173 |
| 91 | Constricted visual fields (HP:0001133) | 1.82228089 |
| 92 | Methylmalonic aciduria (HP:0012120) | 1.82027656 |
| 93 | Abolished electroretinogram (ERG) (HP:0000550) | 1.81872526 |
| 94 | Abnormality of T cell physiology (HP:0011840) | 1.81152255 |
| 95 | Hemoptysis (HP:0002105) | 1.80955095 |
| 96 | IgM deficiency (HP:0002850) | 1.78129429 |
| 97 | Bronchitis (HP:0012387) | 1.77421740 |
| 98 | Radial bowing (HP:0002986) | 1.76378467 |
| 99 | Pancreatitis (HP:0001733) | 1.74398297 |
| 100 | Ketosis (HP:0001946) | 1.73972870 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 7.37343192 |
| 2 | KDR | 6.32670129 |
| 3 | TESK2 | 3.94252000 |
| 4 | BCKDK | 3.67572201 |
| 5 | ITK | 2.35836053 |
| 6 | TESK1 | 2.12620012 |
| 7 | MAP4K1 | 2.06929092 |
| 8 | LIMK1 | 1.98319028 |
| 9 | BUB1 | 1.89879760 |
| 10 | VRK2 | 1.85344795 |
| 11 | ADRBK2 | 1.80935636 |
| 12 | MAP3K12 | 1.68610363 |
| 13 | FES | 1.59913930 |
| 14 | GRK1 | 1.58044030 |
| 15 | ZAK | 1.56510599 |
| 16 | MAP4K2 | 1.48873275 |
| 17 | MST4 | 1.48226495 |
| 18 | PRKCQ | 1.35845066 |
| 19 | CSK | 1.35638099 |
| 20 | VRK1 | 1.32696108 |
| 21 | SYK | 1.24765473 |
| 22 | TAOK3 | 1.24084056 |
| 23 | GRK7 | 1.23532962 |
| 24 | MAP3K11 | 1.22272034 |
| 25 | STK16 | 1.21396866 |
| 26 | SCYL2 | 1.19529733 |
| 27 | TLK1 | 1.19321812 |
| 28 | LCK | 1.17390541 |
| 29 | WNK4 | 1.15535989 |
| 30 | TEC | 1.05816395 |
| 31 | PINK1 | 1.01823216 |
| 32 | MAP2K7 | 1.01146225 |
| 33 | NUAK1 | 0.97955433 |
| 34 | PIM2 | 0.97871720 |
| 35 | BTK | 0.96183180 |
| 36 | BCR | 0.94866556 |
| 37 | PIK3CA | 0.91396537 |
| 38 | MUSK | 0.89585166 |
| 39 | MYLK | 0.87749479 |
| 40 | TNK2 | 0.85871150 |
| 41 | MAP2K6 | 0.85861866 |
| 42 | GRK6 | 0.85220592 |
| 43 | PASK | 0.80002350 |
| 44 | TIE1 | 0.79251337 |
| 45 | CAMKK2 | 0.79238494 |
| 46 | LYN | 0.78455191 |
| 47 | IKBKB | 0.78279760 |
| 48 | ZAP70 | 0.74999047 |
| 49 | NME1 | 0.72227109 |
| 50 | TYRO3 | 0.71032372 |
| 51 | DAPK1 | 0.68689232 |
| 52 | FYN | 0.68302277 |
| 53 | MAPKAPK3 | 0.67546860 |
| 54 | RPS6KA5 | 0.65368004 |
| 55 | CSNK1G3 | 0.64248727 |
| 56 | OBSCN | 0.63923229 |
| 57 | INSRR | 0.63244871 |
| 58 | PIK3CG | 0.62987302 |
| 59 | FRK | 0.60697070 |
| 60 | AURKA | 0.58847995 |
| 61 | WNK3 | 0.58770894 |
| 62 | TRIM28 | 0.58553417 |
| 63 | CDK19 | 0.56501664 |
| 64 | BMPR1B | 0.56415404 |
| 65 | PIM1 | 0.55900613 |
| 66 | MAP3K5 | 0.55298847 |
| 67 | DAPK2 | 0.54869808 |
| 68 | CSF1R | 0.52976065 |
| 69 | ROCK1 | 0.51752185 |
| 70 | RPS6KA4 | 0.50742486 |
| 71 | CAMKK1 | 0.50548411 |
| 72 | SRPK1 | 0.50335261 |
| 73 | IKBKE | 0.49645091 |
| 74 | EIF2AK3 | 0.49547147 |
| 75 | IGF1R | 0.49530413 |
| 76 | MAPK13 | 0.47085618 |
| 77 | CSNK1G2 | 0.46386476 |
| 78 | PAK1 | 0.46279759 |
| 79 | PRKCA | 0.45612625 |
| 80 | JAK3 | 0.44823900 |
| 81 | CAMK2A | 0.43649975 |
| 82 | CSNK1A1L | 0.41314469 |
| 83 | ADRBK1 | 0.40517278 |
| 84 | PLK4 | 0.40288259 |
| 85 | PRKACA | 0.38757163 |
| 86 | INSR | 0.36057459 |
| 87 | DAPK3 | 0.35775496 |
| 88 | CSNK1G1 | 0.35534055 |
| 89 | DYRK2 | 0.35234480 |
| 90 | OXSR1 | 0.34801526 |
| 91 | CSNK2A1 | 0.34196150 |
| 92 | CLK1 | 0.30872862 |
| 93 | TBK1 | 0.30413786 |
| 94 | PLK2 | 0.28267838 |
| 95 | PDK2 | 0.27364767 |
| 96 | ATR | 0.26858806 |
| 97 | ARAF | 0.26410125 |
| 98 | CSNK1A1 | 0.25359854 |
| 99 | MATK | 0.24951091 |
| 100 | JAK2 | 0.22197865 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.24102143 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.92543366 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.87210875 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.22783118 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.00630738 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.85194392 |
| 7 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.75402544 |
| 8 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.59738420 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.57414868 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.41989283 |
| 11 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.37828319 |
| 12 | Ribosome_Homo sapiens_hsa03010 | 2.23723827 |
| 13 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.20365317 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.19402707 |
| 15 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.10535640 |
| 16 | Protein export_Homo sapiens_hsa03060 | 2.03105052 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 2.02605544 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.01105453 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.91492959 |
| 20 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.90551124 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.71946131 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.48575827 |
| 23 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.34233937 |
| 24 | Salmonella infection_Homo sapiens_hsa05132 | 1.34156518 |
| 25 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.30512934 |
| 26 | Measles_Homo sapiens_hsa05162 | 1.23790543 |
| 27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.19160126 |
| 28 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.08289318 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99857664 |
| 30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.96090811 |
| 31 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.95976629 |
| 32 | Shigellosis_Homo sapiens_hsa05131 | 0.95825359 |
| 33 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.95655860 |
| 34 | Viral myocarditis_Homo sapiens_hsa05416 | 0.93932760 |
| 35 | Peroxisome_Homo sapiens_hsa04146 | 0.92626908 |
| 36 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.91619496 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.87291899 |
| 38 | Malaria_Homo sapiens_hsa05144 | 0.86468702 |
| 39 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.85191530 |
| 40 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.84748651 |
| 41 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.84096242 |
| 42 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.83716563 |
| 43 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.83151922 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.82072078 |
| 45 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.76911095 |
| 46 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.76373778 |
| 47 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.71584592 |
| 48 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.71049907 |
| 49 | Homologous recombination_Homo sapiens_hsa03440 | 0.70827406 |
| 50 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.69716354 |
| 51 | Retinol metabolism_Homo sapiens_hsa00830 | 0.63452741 |
| 52 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.62206302 |
| 53 | Asthma_Homo sapiens_hsa05310 | 0.61901317 |
| 54 | RNA degradation_Homo sapiens_hsa03018 | 0.61489164 |
| 55 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61372422 |
| 56 | Purine metabolism_Homo sapiens_hsa00230 | 0.59780510 |
| 57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.58819962 |
| 58 | DNA replication_Homo sapiens_hsa03030 | 0.56969188 |
| 59 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.54599647 |
| 60 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.52399713 |
| 61 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.50409888 |
| 62 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.49556045 |
| 63 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.48557233 |
| 64 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.45935537 |
| 65 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.42987503 |
| 66 | Nicotine addiction_Homo sapiens_hsa05033 | 0.42168229 |
| 67 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.41706066 |
| 68 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.41649313 |
| 69 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41098233 |
| 70 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.40146001 |
| 71 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.40102656 |
| 72 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.39780554 |
| 73 | Metabolic pathways_Homo sapiens_hsa01100 | 0.39371796 |
| 74 | Spliceosome_Homo sapiens_hsa03040 | 0.38164579 |
| 75 | Mismatch repair_Homo sapiens_hsa03430 | 0.36001046 |
| 76 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.35423058 |
| 77 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.34806792 |
| 78 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.33887450 |
| 79 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33460810 |
| 80 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.32505222 |
| 81 | Prion diseases_Homo sapiens_hsa05020 | 0.31215657 |
| 82 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.28963010 |
| 83 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.28665687 |
| 84 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.27740730 |
| 85 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.27728864 |
| 86 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.26962832 |
| 87 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.22862956 |
| 88 | Morphine addiction_Homo sapiens_hsa05032 | 0.21128963 |
| 89 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.20283030 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.19136297 |
| 91 | Legionellosis_Homo sapiens_hsa05134 | 0.17955683 |
| 92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.17551212 |
| 93 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.16920380 |
| 94 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.16545408 |
| 95 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.15812341 |
| 96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.15755969 |
| 97 | GABAergic synapse_Homo sapiens_hsa04727 | 0.15674038 |
| 98 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.15617427 |
| 99 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.15159908 |
| 100 | Alcoholism_Homo sapiens_hsa05034 | 0.14062089 |

