

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit biogenesis (GO:0042274) | 9.59243096 |
| 2 | viral transcription (GO:0019083) | 9.34786646 |
| 3 | translational termination (GO:0006415) | 8.97672014 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 8.14401491 |
| 5 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 7.36132154 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 7.28153088 |
| 7 | translational elongation (GO:0006414) | 7.27127421 |
| 8 | protein targeting to ER (GO:0045047) | 7.18800828 |
| 9 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.86881448 |
| 10 | cellular protein complex disassembly (GO:0043624) | 6.79453027 |
| 11 | viral life cycle (GO:0019058) | 6.77432754 |
| 12 | protein localization to endoplasmic reticulum (GO:0070972) | 6.71751064 |
| 13 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 6.56468849 |
| 14 | maturation of SSU-rRNA (GO:0030490) | 6.26784625 |
| 15 | protein complex disassembly (GO:0043241) | 5.79289650 |
| 16 | ribosomal large subunit biogenesis (GO:0042273) | 5.77866822 |
| 17 | translational initiation (GO:0006413) | 5.59740985 |
| 18 | macromolecular complex disassembly (GO:0032984) | 5.42560383 |
| 19 | behavioral response to nicotine (GO:0035095) | 5.32130188 |
| 20 | ATP synthesis coupled proton transport (GO:0015986) | 5.06368519 |
| 21 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.06368519 |
| 22 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.93567065 |
| 23 | protein targeting to membrane (GO:0006612) | 4.89121703 |
| 24 | cell proliferation in forebrain (GO:0021846) | 4.58111396 |
| 25 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 4.42127659 |
| 26 | translation (GO:0006412) | 4.37597407 |
| 27 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.29806776 |
| 28 | cellular component biogenesis (GO:0044085) | 4.20803584 |
| 29 | mRNA catabolic process (GO:0006402) | 4.15865190 |
| 30 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.04404358 |
| 31 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.04283774 |
| 32 | regulation of cellular respiration (GO:0043457) | 4.02885799 |
| 33 | chaperone-mediated protein transport (GO:0072321) | 3.88402213 |
| 34 | protein neddylation (GO:0045116) | 3.79457591 |
| 35 | RNA catabolic process (GO:0006401) | 3.60069188 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.56215160 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.56215160 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.56215160 |
| 39 | electron transport chain (GO:0022900) | 3.52819644 |
| 40 | respiratory electron transport chain (GO:0022904) | 3.51881489 |
| 41 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.46716563 |
| 42 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.46716563 |
| 43 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.45087228 |
| 44 | axonemal dynein complex assembly (GO:0070286) | 3.43811747 |
| 45 | negative regulation of mast cell activation (GO:0033004) | 3.35137817 |
| 46 | ATP biosynthetic process (GO:0006754) | 3.27368990 |
| 47 | ubiquinone biosynthetic process (GO:0006744) | 3.26155291 |
| 48 | establishment of protein localization to membrane (GO:0090150) | 3.23544192 |
| 49 | forebrain morphogenesis (GO:0048853) | 3.20919695 |
| 50 | protein complex biogenesis (GO:0070271) | 3.17745948 |
| 51 | protein targeting (GO:0006605) | 3.17435959 |
| 52 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.15472209 |
| 53 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 3.15196584 |
| 54 | negative regulation of glycogen biosynthetic process (GO:0045719) | 3.11320221 |
| 55 | ribosome biogenesis (GO:0042254) | 3.03816672 |
| 56 | mitochondrion transport along microtubule (GO:0047497) | 3.03298145 |
| 57 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.03298145 |
| 58 | ubiquinone metabolic process (GO:0006743) | 3.02741559 |
| 59 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.02580854 |
| 60 | regulation of cilium movement (GO:0003352) | 2.98342272 |
| 61 | epithelial cilium movement (GO:0003351) | 2.95796588 |
| 62 | regulation of microtubule-based movement (GO:0060632) | 2.94127479 |
| 63 | establishment of mitochondrion localization (GO:0051654) | 2.93812500 |
| 64 | positive regulation of T cell apoptotic process (GO:0070234) | 2.92734218 |
| 65 | cardiovascular system development (GO:0072358) | 2.89914545 |
| 66 | termination of RNA polymerase III transcription (GO:0006386) | 2.89692228 |
| 67 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.89692228 |
| 68 | response to redox state (GO:0051775) | 2.88782434 |
| 69 | peptidyl-histidine modification (GO:0018202) | 2.88633694 |
| 70 | establishment of protein localization to organelle (GO:0072594) | 2.88140372 |
| 71 | rRNA processing (GO:0006364) | 2.85840107 |
| 72 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.83888974 |
| 73 | negative regulation of muscle hypertrophy (GO:0014741) | 2.83779517 |
| 74 | regulation of activation of Janus kinase activity (GO:0010533) | 2.82858454 |
| 75 | protein polyglutamylation (GO:0018095) | 2.82704911 |
| 76 | synaptic transmission, cholinergic (GO:0007271) | 2.82549021 |
| 77 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.80289889 |
| 78 | GTP biosynthetic process (GO:0006183) | 2.77799068 |
| 79 | rRNA metabolic process (GO:0016072) | 2.77115376 |
| 80 | DNA deamination (GO:0045006) | 2.76223378 |
| 81 | negative regulation of response to food (GO:0032096) | 2.76215972 |
| 82 | negative regulation of appetite (GO:0032099) | 2.76215972 |
| 83 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 2.74580533 |
| 84 | nucleobase catabolic process (GO:0046113) | 2.73018383 |
| 85 | respiratory chain complex IV assembly (GO:0008535) | 2.71277727 |
| 86 | ncRNA 3-end processing (GO:0043628) | 2.68849633 |
| 87 | maturation of 5.8S rRNA (GO:0000460) | 2.66718644 |
| 88 | motile cilium assembly (GO:0044458) | 2.66540673 |
| 89 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.66121827 |
| 90 | pattern specification involved in kidney development (GO:0061004) | 2.62504105 |
| 91 | spinal cord association neuron differentiation (GO:0021527) | 2.61649208 |
| 92 | nonmotile primary cilium assembly (GO:0035058) | 2.61501351 |
| 93 | sequestering of actin monomers (GO:0042989) | 2.60801165 |
| 94 | cilium movement (GO:0003341) | 2.60214613 |
| 95 | protein localization to membrane (GO:0072657) | 2.59241381 |
| 96 | quinone biosynthetic process (GO:1901663) | 2.58693532 |
| 97 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.57730459 |
| 98 | transmission of nerve impulse (GO:0019226) | 2.50953244 |
| 99 | regulation of energy homeostasis (GO:2000505) | 2.50425616 |
| 100 | neuron fate determination (GO:0048664) | 2.48122224 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.50032544 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.43572661 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.09505270 |
| 4 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.44078010 |
| 5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.35628167 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.24179612 |
| 7 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.16679306 |
| 8 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.15915537 |
| 9 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.15077297 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.11615573 |
| 11 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.10020817 |
| 12 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.03003596 |
| 13 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.00887298 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.94888282 |
| 15 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.91460636 |
| 16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.87113468 |
| 17 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.86998074 |
| 18 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.83743722 |
| 19 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.82683239 |
| 20 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.79958436 |
| 21 | VDR_22108803_ChIP-Seq_LS180_Human | 1.70703552 |
| 22 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.69185896 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.66548735 |
| 24 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.65009905 |
| 25 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.64941682 |
| 26 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.62716968 |
| 27 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.61671580 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.60127011 |
| 29 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.55980152 |
| 30 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.55670218 |
| 31 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.53642316 |
| 32 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.53642316 |
| 33 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.53502728 |
| 34 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.53347563 |
| 35 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.53316886 |
| 36 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.53010974 |
| 37 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.51677847 |
| 38 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.49523979 |
| 39 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.46153070 |
| 40 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.43750474 |
| 41 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.43097687 |
| 42 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.40783644 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.39593326 |
| 44 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.36796686 |
| 45 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.33749205 |
| 46 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.32824607 |
| 47 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.32142663 |
| 48 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.31556293 |
| 49 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.31259258 |
| 50 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.27582970 |
| 51 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.27341743 |
| 52 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.26535324 |
| 53 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.25496051 |
| 54 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24808800 |
| 55 | P68_20966046_ChIP-Seq_HELA_Human | 1.24474808 |
| 56 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21282900 |
| 57 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.20224100 |
| 58 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.19158930 |
| 59 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.18690066 |
| 60 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.16867279 |
| 61 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.16842655 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.16063331 |
| 63 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.15949274 |
| 64 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.15912018 |
| 65 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.15785927 |
| 66 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.15641778 |
| 67 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.14133982 |
| 68 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.13301602 |
| 69 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.13078345 |
| 70 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.12758475 |
| 71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12103185 |
| 72 | SA1_27219007_Chip-Seq_Bcells_Human | 1.11598456 |
| 73 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11547281 |
| 74 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11391529 |
| 75 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.10543194 |
| 76 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.10399985 |
| 77 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.10383604 |
| 78 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.09144087 |
| 79 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.08897345 |
| 80 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.08834192 |
| 81 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08581290 |
| 82 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.08414626 |
| 83 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.05886158 |
| 84 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.05503001 |
| 85 | P300_27268052_Chip-Seq_Bcells_Human | 1.05090753 |
| 86 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.04315336 |
| 87 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.04000981 |
| 88 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.02151641 |
| 89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.01631631 |
| 90 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.01127204 |
| 91 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.99948828 |
| 92 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.98850300 |
| 93 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.98212920 |
| 94 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.98068624 |
| 95 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.97262736 |
| 96 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.97194414 |
| 97 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.95941372 |
| 98 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.94981777 |
| 99 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 0.94809658 |
| 100 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.94718661 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.50505870 |
| 2 | MP0006292_abnormal_olfactory_placode | 5.17383113 |
| 3 | MP0002653_abnormal_ependyma_morphology | 4.30176237 |
| 4 | MP0002837_dystrophic_cardiac_calcinosis | 2.99214284 |
| 5 | MP0003787_abnormal_imprinting | 2.96043100 |
| 6 | MP0003122_maternal_imprinting | 2.91593277 |
| 7 | MP0003123_paternal_imprinting | 2.85706056 |
| 8 | MP0008789_abnormal_olfactory_epithelium | 2.55498014 |
| 9 | MP0002163_abnormal_gland_morphology | 2.42197484 |
| 10 | MP0003646_muscle_fatigue | 2.37341035 |
| 11 | MP0005394_taste/olfaction_phenotype | 2.36211385 |
| 12 | MP0005499_abnormal_olfactory_system | 2.36211385 |
| 13 | MP0000049_abnormal_middle_ear | 2.13764473 |
| 14 | MP0002102_abnormal_ear_morphology | 2.01726089 |
| 15 | MP0001986_abnormal_taste_sensitivity | 2.00803214 |
| 16 | MP0004145_abnormal_muscle_electrophysio | 1.98643732 |
| 17 | MP0004142_abnormal_muscle_tone | 1.94269940 |
| 18 | MP0001348_abnormal_lacrimal_gland | 1.92968256 |
| 19 | MP0003121_genomic_imprinting | 1.92932888 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.85305851 |
| 21 | MP0003878_abnormal_ear_physiology | 1.85305851 |
| 22 | MP0008877_abnormal_DNA_methylation | 1.73873306 |
| 23 | MP0005379_endocrine/exocrine_gland_phen | 1.73452391 |
| 24 | MP0002160_abnormal_reproductive_system | 1.61415768 |
| 25 | MP0001968_abnormal_touch/_nociception | 1.58366115 |
| 26 | MP0001293_anophthalmia | 1.51026690 |
| 27 | MP0005646_abnormal_pituitary_gland | 1.46255986 |
| 28 | MP0002733_abnormal_thermal_nociception | 1.46117753 |
| 29 | MP0000678_abnormal_parathyroid_gland | 1.42768856 |
| 30 | MP0006276_abnormal_autonomic_nervous | 1.38533805 |
| 31 | MP0002272_abnormal_nervous_system | 1.37829898 |
| 32 | MP0005389_reproductive_system_phenotype | 1.35819107 |
| 33 | MP0009046_muscle_twitch | 1.34174446 |
| 34 | MP0002736_abnormal_nociception_after | 1.30887192 |
| 35 | MP0002638_abnormal_pupillary_reflex | 1.30337608 |
| 36 | MP0001485_abnormal_pinna_reflex | 1.29998553 |
| 37 | MP0001970_abnormal_pain_threshold | 1.26517892 |
| 38 | MP0004130_abnormal_muscle_cell | 1.26331397 |
| 39 | MP0009745_abnormal_behavioral_response | 1.25247451 |
| 40 | MP0000778_abnormal_nervous_system | 1.16439366 |
| 41 | MP0008872_abnormal_physiological_respon | 1.16412826 |
| 42 | MP0003880_abnormal_central_pattern | 1.14947303 |
| 43 | MP0001984_abnormal_olfaction | 1.14281744 |
| 44 | MP0001440_abnormal_grooming_behavior | 1.13048523 |
| 45 | MP0003186_abnormal_redox_activity | 1.12715216 |
| 46 | MP0001529_abnormal_vocalization | 1.11597317 |
| 47 | MP0005551_abnormal_eye_electrophysiolog | 1.11271251 |
| 48 | MP0002095_abnormal_skin_pigmentation | 1.11258011 |
| 49 | MP0003938_abnormal_ear_development | 1.09054738 |
| 50 | MP0005423_abnormal_somatic_nervous | 1.07940473 |
| 51 | MP0004133_heterotaxia | 1.06788092 |
| 52 | MP0001919_abnormal_reproductive_system | 1.04691703 |
| 53 | MP0004885_abnormal_endolymph | 1.03128626 |
| 54 | MP0006054_spinal_hemorrhage | 1.02903349 |
| 55 | MP0002735_abnormal_chemical_nociception | 1.01931554 |
| 56 | MP0002234_abnormal_pharynx_morphology | 1.01590626 |
| 57 | MP0003635_abnormal_synaptic_transmissio | 1.01168895 |
| 58 | MP0000569_abnormal_digit_pigmentation | 1.00239879 |
| 59 | MP0004742_abnormal_vestibular_system | 0.97737609 |
| 60 | MP0003879_abnormal_hair_cell | 0.96873949 |
| 61 | MP0003011_delayed_dark_adaptation | 0.96184382 |
| 62 | MP0010030_abnormal_orbit_morphology | 0.95775401 |
| 63 | MP0002938_white_spotting | 0.95769170 |
| 64 | MP0001905_abnormal_dopamine_level | 0.94283758 |
| 65 | MP0000631_abnormal_neuroendocrine_gland | 0.94035789 |
| 66 | MP0001502_abnormal_circadian_rhythm | 0.93948763 |
| 67 | MP0004084_abnormal_cardiac_muscle | 0.93311800 |
| 68 | MP0005174_abnormal_tail_pigmentation | 0.92813591 |
| 69 | MP0002557_abnormal_social/conspecific_i | 0.92567736 |
| 70 | MP0003942_abnormal_urinary_system | 0.90076471 |
| 71 | MP0000026_abnormal_inner_ear | 0.88363952 |
| 72 | MP0002063_abnormal_learning/memory/cond | 0.88345378 |
| 73 | MP0002734_abnormal_mechanical_nocicepti | 0.88123093 |
| 74 | MP0008775_abnormal_heart_ventricle | 0.88062077 |
| 75 | MP0005195_abnormal_posterior_eye | 0.87045505 |
| 76 | MP0002572_abnormal_emotion/affect_behav | 0.86426554 |
| 77 | MP0002277_abnormal_respiratory_mucosa | 0.86335819 |
| 78 | MP0002249_abnormal_larynx_morphology | 0.85197867 |
| 79 | MP0002876_abnormal_thyroid_physiology | 0.85186854 |
| 80 | MP0002822_catalepsy | 0.85025399 |
| 81 | MP0006072_abnormal_retinal_apoptosis | 0.82494516 |
| 82 | MP0001286_abnormal_eye_development | 0.82434539 |
| 83 | MP0002752_abnormal_somatic_nervous | 0.79951731 |
| 84 | MP0002064_seizures | 0.79236411 |
| 85 | MP0002184_abnormal_innervation | 0.78986222 |
| 86 | MP0000015_abnormal_ear_pigmentation | 0.77531105 |
| 87 | MP0001963_abnormal_hearing_physiology | 0.76981894 |
| 88 | MP0003936_abnormal_reproductive_system | 0.76579103 |
| 89 | MP0002233_abnormal_nose_morphology | 0.76156631 |
| 90 | MP0004859_abnormal_synaptic_plasticity | 0.74819208 |
| 91 | MP0000955_abnormal_spinal_cord | 0.74626488 |
| 92 | MP0003693_abnormal_embryo_hatching | 0.74597120 |
| 93 | MP0003937_abnormal_limbs/digits/tail_de | 0.73404497 |
| 94 | MP0001324_abnormal_eye_pigmentation | 0.68765545 |
| 95 | MP0009250_abnormal_appendicular_skeleto | 0.68051572 |
| 96 | MP0003755_abnormal_palate_morphology | 0.67652684 |
| 97 | MP0002697_abnormal_eye_size | 0.67164804 |
| 98 | MP0003136_yellow_coat_color | 0.66474436 |
| 99 | MP0003567_abnormal_fetal_cardiomyocyte | 0.65460147 |
| 100 | MP0002116_abnormal_craniofacial_bone | 0.65371529 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 5.43603589 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 5.26340219 |
| 3 | Chronic hepatic failure (HP:0100626) | 5.21928400 |
| 4 | Acute necrotizing encephalopathy (HP:0006965) | 4.35004329 |
| 5 | Abnormal number of erythroid precursors (HP:0012131) | 4.33143425 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.82919923 |
| 7 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.80024764 |
| 8 | Absent/shortened dynein arms (HP:0200106) | 3.80024764 |
| 9 | Macrocytic anemia (HP:0001972) | 3.78412160 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.49260727 |
| 11 | Acute encephalopathy (HP:0006846) | 3.48620111 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.44978750 |
| 13 | Septo-optic dysplasia (HP:0100842) | 3.28101433 |
| 14 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.21911991 |
| 15 | Abnormal ciliary motility (HP:0012262) | 3.19635125 |
| 16 | Pancreatic cysts (HP:0001737) | 3.16129701 |
| 17 | Pallor (HP:0000980) | 3.15596721 |
| 18 | Abnormality of midbrain morphology (HP:0002418) | 3.14345859 |
| 19 | Molar tooth sign on MRI (HP:0002419) | 3.14345859 |
| 20 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.09993775 |
| 21 | Increased CSF lactate (HP:0002490) | 3.07688218 |
| 22 | Pancreatic fibrosis (HP:0100732) | 3.03386029 |
| 23 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.78486746 |
| 24 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.78486746 |
| 25 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.74463964 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.74252889 |
| 27 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.63415372 |
| 28 | Anophthalmia (HP:0000528) | 2.62188852 |
| 29 | Increased hepatocellular lipid droplets (HP:0006565) | 2.61493549 |
| 30 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.55197181 |
| 31 | Tubular atrophy (HP:0000092) | 2.55172258 |
| 32 | Pendular nystagmus (HP:0012043) | 2.54379328 |
| 33 | Rib fusion (HP:0000902) | 2.53242501 |
| 34 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.52169823 |
| 35 | Cystic liver disease (HP:0006706) | 2.51794934 |
| 36 | Cerebral edema (HP:0002181) | 2.49941258 |
| 37 | Stenosis of the external auditory canal (HP:0000402) | 2.49597187 |
| 38 | Asplenia (HP:0001746) | 2.47973121 |
| 39 | Myokymia (HP:0002411) | 2.42098592 |
| 40 | Nephronophthisis (HP:0000090) | 2.41980723 |
| 41 | Congenital stationary night blindness (HP:0007642) | 2.40801426 |
| 42 | Optic disc pallor (HP:0000543) | 2.35395405 |
| 43 | Type II lissencephaly (HP:0007260) | 2.34397525 |
| 44 | True hermaphroditism (HP:0010459) | 2.33990139 |
| 45 | Renovascular hypertension (HP:0100817) | 2.33611587 |
| 46 | Abnormality of the diencephalon (HP:0010662) | 2.33294740 |
| 47 | Polydipsia (HP:0001959) | 2.32979116 |
| 48 | Abnormal drinking behavior (HP:0030082) | 2.32979116 |
| 49 | Hyperthyroidism (HP:0000836) | 2.32910514 |
| 50 | Lipid accumulation in hepatocytes (HP:0006561) | 2.32900935 |
| 51 | 3-Methylglutaconic aciduria (HP:0003535) | 2.31794350 |
| 52 | Abnormal number of incisors (HP:0011064) | 2.29635981 |
| 53 | Adrenal hypoplasia (HP:0000835) | 2.26726742 |
| 54 | Hepatocellular necrosis (HP:0001404) | 2.26510876 |
| 55 | Elfin facies (HP:0004428) | 2.25768651 |
| 56 | Absent thumb (HP:0009777) | 2.14623324 |
| 57 | Sclerocornea (HP:0000647) | 2.12865414 |
| 58 | Rhinitis (HP:0012384) | 2.07153258 |
| 59 | Depressed nasal ridge (HP:0000457) | 2.05616093 |
| 60 | Hepatic necrosis (HP:0002605) | 2.04868430 |
| 61 | Renal duplication (HP:0000075) | 2.04754948 |
| 62 | Abnormality of the renal medulla (HP:0100957) | 2.03019444 |
| 63 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.01489225 |
| 64 | Absent septum pellucidum (HP:0001331) | 1.98763084 |
| 65 | Increased serum lactate (HP:0002151) | 1.98317880 |
| 66 | Anencephaly (HP:0002323) | 1.97461282 |
| 67 | Overriding aorta (HP:0002623) | 1.97007819 |
| 68 | Severe visual impairment (HP:0001141) | 1.96884390 |
| 69 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.94166771 |
| 70 | Oligodactyly (hands) (HP:0001180) | 1.93299993 |
| 71 | Limb dystonia (HP:0002451) | 1.92758183 |
| 72 | Abnormal hemoglobin (HP:0011902) | 1.92731646 |
| 73 | Medial flaring of the eyebrow (HP:0010747) | 1.89997631 |
| 74 | Testicular atrophy (HP:0000029) | 1.89412583 |
| 75 | Agitation (HP:0000713) | 1.88766121 |
| 76 | Stomatitis (HP:0010280) | 1.88753286 |
| 77 | Microretrognathia (HP:0000308) | 1.87897863 |
| 78 | Optic nerve hypoplasia (HP:0000609) | 1.87487599 |
| 79 | Growth hormone deficiency (HP:0000824) | 1.86120401 |
| 80 | Abnormality of the renal cortex (HP:0011035) | 1.85342818 |
| 81 | Leukodystrophy (HP:0002415) | 1.84423667 |
| 82 | Impulsivity (HP:0100710) | 1.84154417 |
| 83 | Tubulointerstitial nephritis (HP:0001970) | 1.83855328 |
| 84 | Maternal diabetes (HP:0009800) | 1.83534351 |
| 85 | Abnormality of renal resorption (HP:0011038) | 1.83491393 |
| 86 | Chronic bronchitis (HP:0004469) | 1.82939202 |
| 87 | Optic nerve coloboma (HP:0000588) | 1.80501974 |
| 88 | Increased intramyocellular lipid droplets (HP:0012240) | 1.79448077 |
| 89 | Bile duct proliferation (HP:0001408) | 1.79048997 |
| 90 | Abnormal biliary tract physiology (HP:0012439) | 1.79048997 |
| 91 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.78123899 |
| 92 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.76262755 |
| 93 | Postaxial foot polydactyly (HP:0001830) | 1.74377997 |
| 94 | Progressive cerebellar ataxia (HP:0002073) | 1.74288255 |
| 95 | Type 2 muscle fiber atrophy (HP:0003554) | 1.74110798 |
| 96 | Oligodactyly (HP:0012165) | 1.69502025 |
| 97 | Polyuria (HP:0000103) | 1.68593368 |
| 98 | Abnormality of urine glucose concentration (HP:0011016) | 1.66171085 |
| 99 | Glycosuria (HP:0003076) | 1.66171085 |
| 100 | Occipital encephalocele (HP:0002085) | 1.65762723 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | PASK | 5.53861591 |
| 2 | CAMKK1 | 4.31560132 |
| 3 | CAMKK2 | 3.71545501 |
| 4 | WNK4 | 2.76908936 |
| 5 | ADRBK2 | 2.72404050 |
| 6 | LIMK1 | 2.56888093 |
| 7 | TXK | 2.41134945 |
| 8 | LRRK2 | 2.39639264 |
| 9 | DYRK2 | 2.30614254 |
| 10 | BCKDK | 2.01804863 |
| 11 | BRSK1 | 1.94616173 |
| 12 | MAP3K13 | 1.81890535 |
| 13 | GRK1 | 1.71270633 |
| 14 | MAP3K11 | 1.67305977 |
| 15 | NME2 | 1.60220693 |
| 16 | NUAK1 | 1.51807720 |
| 17 | PINK1 | 1.51670679 |
| 18 | BRSK2 | 1.44163213 |
| 19 | TIE1 | 1.40873910 |
| 20 | CASK | 1.40642214 |
| 21 | EPHB2 | 1.36576417 |
| 22 | ZAK | 1.22293326 |
| 23 | CDC42BPA | 1.22073731 |
| 24 | CDK8 | 1.22025082 |
| 25 | MARK1 | 1.20386987 |
| 26 | CDK19 | 1.20072525 |
| 27 | NTRK2 | 1.20060309 |
| 28 | MAPK13 | 1.17639107 |
| 29 | SIK2 | 1.15370352 |
| 30 | PDK2 | 1.10473432 |
| 31 | PTK6 | 1.07864595 |
| 32 | MAP4K2 | 1.07844511 |
| 33 | PRKCQ | 1.07146093 |
| 34 | TLK1 | 1.07110499 |
| 35 | PRKCG | 1.04991661 |
| 36 | AURKA | 1.02412728 |
| 37 | MAP2K7 | 1.00934015 |
| 38 | CAMK1 | 1.00914141 |
| 39 | MAP4K1 | 0.99174991 |
| 40 | FRK | 0.98635924 |
| 41 | INSRR | 0.96121648 |
| 42 | TYRO3 | 0.94385189 |
| 43 | NEK2 | 0.91962712 |
| 44 | STK16 | 0.90868980 |
| 45 | BMPR1B | 0.90535034 |
| 46 | KDR | 0.89314791 |
| 47 | STK11 | 0.87858111 |
| 48 | MKNK2 | 0.86835797 |
| 49 | PIK3CA | 0.86169471 |
| 50 | ADRBK1 | 0.83458942 |
| 51 | RPS6KA5 | 0.80161884 |
| 52 | BTK | 0.79872114 |
| 53 | SRPK1 | 0.75199466 |
| 54 | EPHA4 | 0.73327127 |
| 55 | PAK3 | 0.73186372 |
| 56 | PHKG2 | 0.71505862 |
| 57 | PHKG1 | 0.71505862 |
| 58 | WNK1 | 0.70867494 |
| 59 | PIM2 | 0.67255177 |
| 60 | MINK1 | 0.64931875 |
| 61 | PRKCZ | 0.64253549 |
| 62 | WNK3 | 0.62772086 |
| 63 | PRKACA | 0.59094769 |
| 64 | MAP3K4 | 0.58000911 |
| 65 | CDC7 | 0.57971825 |
| 66 | CAMK1D | 0.57076451 |
| 67 | SGK223 | 0.55850210 |
| 68 | SGK494 | 0.55850210 |
| 69 | PRKCD | 0.55033120 |
| 70 | OBSCN | 0.54966113 |
| 71 | CSNK1G2 | 0.53126256 |
| 72 | PRKCH | 0.52893708 |
| 73 | CSNK2A2 | 0.52723646 |
| 74 | ABL2 | 0.52517330 |
| 75 | CAMK4 | 0.51681431 |
| 76 | SGK1 | 0.50925433 |
| 77 | RPS6KA6 | 0.50817455 |
| 78 | STK39 | 0.50462577 |
| 79 | CSNK1G3 | 0.49964818 |
| 80 | OXSR1 | 0.48838412 |
| 81 | CSNK1E | 0.46521253 |
| 82 | PLK4 | 0.46094255 |
| 83 | TEC | 0.43913717 |
| 84 | PRKCA | 0.41771875 |
| 85 | ITK | 0.41324895 |
| 86 | CAMK1G | 0.40884879 |
| 87 | MARK2 | 0.39852754 |
| 88 | SYK | 0.38899420 |
| 89 | LCK | 0.38894969 |
| 90 | RIPK4 | 0.38558339 |
| 91 | RPS6KA1 | 0.38125235 |
| 92 | MAPK12 | 0.37852989 |
| 93 | PLK1 | 0.36251392 |
| 94 | ATR | 0.34670873 |
| 95 | MUSK | 0.34548444 |
| 96 | PRKCI | 0.33776851 |
| 97 | CSNK1G1 | 0.33368729 |
| 98 | IKBKB | 0.32777259 |
| 99 | ROCK1 | 0.32365611 |
| 100 | RPS6KA3 | 0.32121614 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.93485368 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.01050354 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.51424413 |
| 4 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.69545336 |
| 5 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.59755040 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.48218483 |
| 7 | Alzheimers disease_Homo sapiens_hsa05010 | 2.40250486 |
| 8 | Huntingtons disease_Homo sapiens_hsa05016 | 2.40074328 |
| 9 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.13077118 |
| 10 | Sulfur relay system_Homo sapiens_hsa04122 | 2.06607011 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.00343528 |
| 12 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.97778040 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.78634701 |
| 14 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.70630256 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.60184964 |
| 16 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.58972381 |
| 17 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.56077053 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.42240946 |
| 19 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.33773603 |
| 20 | Nicotine addiction_Homo sapiens_hsa05033 | 1.29183654 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26439639 |
| 22 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.23291634 |
| 23 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.22456954 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.16039892 |
| 25 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.13805538 |
| 26 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.12044777 |
| 27 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.11567945 |
| 28 | Homologous recombination_Homo sapiens_hsa03440 | 1.09996100 |
| 29 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.07754819 |
| 30 | Peroxisome_Homo sapiens_hsa04146 | 1.07660322 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.07282371 |
| 32 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.03950522 |
| 33 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.96779727 |
| 34 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.94535152 |
| 35 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.90433992 |
| 36 | Insulin secretion_Homo sapiens_hsa04911 | 0.89288808 |
| 37 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.88824401 |
| 38 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.87502885 |
| 39 | Olfactory transduction_Homo sapiens_hsa04740 | 0.83584625 |
| 40 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.78552345 |
| 41 | Morphine addiction_Homo sapiens_hsa05032 | 0.76671698 |
| 42 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.76107442 |
| 43 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.74852880 |
| 44 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.72099856 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.71713999 |
| 46 | Asthma_Homo sapiens_hsa05310 | 0.71511693 |
| 47 | Metabolic pathways_Homo sapiens_hsa01100 | 0.71408648 |
| 48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.69869251 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.67599915 |
| 50 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64778767 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64338745 |
| 52 | Taste transduction_Homo sapiens_hsa04742 | 0.64255852 |
| 53 | Proteasome_Homo sapiens_hsa03050 | 0.62292877 |
| 54 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.60582460 |
| 55 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.60486233 |
| 56 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.59860592 |
| 57 | Cocaine addiction_Homo sapiens_hsa05030 | 0.59539182 |
| 58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58536801 |
| 59 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.58446008 |
| 60 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.56130876 |
| 61 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.54657123 |
| 62 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.54123332 |
| 63 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53204369 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52833547 |
| 65 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.50569654 |
| 66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.50525984 |
| 67 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50218925 |
| 68 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.49286788 |
| 69 | Basal transcription factors_Homo sapiens_hsa03022 | 0.48794173 |
| 70 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.47867485 |
| 71 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.47596008 |
| 72 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.47028922 |
| 73 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46882586 |
| 74 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.45974664 |
| 75 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.45386903 |
| 76 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.44599082 |
| 77 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.44505395 |
| 78 | GABAergic synapse_Homo sapiens_hsa04727 | 0.42877212 |
| 79 | Axon guidance_Homo sapiens_hsa04360 | 0.42454384 |
| 80 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.41864782 |
| 81 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.41386373 |
| 82 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.41118997 |
| 83 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.41014791 |
| 84 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.40083253 |
| 85 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.39865195 |
| 86 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.38410052 |
| 87 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.34628862 |
| 88 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.31368593 |
| 89 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.31114245 |
| 90 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.30189127 |
| 91 | Spliceosome_Homo sapiens_hsa03040 | 0.29761497 |
| 92 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.28751128 |
| 93 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.26752472 |
| 94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.25651075 |
| 95 | Galactose metabolism_Homo sapiens_hsa00052 | 0.24632721 |
| 96 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.24483073 |
| 97 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.23940278 |
| 98 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.23883564 |
| 99 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.23665245 |
| 100 | Allograft rejection_Homo sapiens_hsa05330 | 0.23473501 |

