

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | cytidine deamination (GO:0009972) | 8.22786308 |
| 2 | cytidine metabolic process (GO:0046087) | 8.22786308 |
| 3 | cytidine catabolic process (GO:0006216) | 8.22786308 |
| 4 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 7.69290461 |
| 5 | DNA deamination (GO:0045006) | 7.41748189 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 7.37619766 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.45379168 |
| 8 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.35785384 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.21734458 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 5.21734458 |
| 11 | ribosomal small subunit assembly (GO:0000028) | 5.08900887 |
| 12 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.81196585 |
| 13 | metallo-sulfur cluster assembly (GO:0031163) | 4.74673363 |
| 14 | iron-sulfur cluster assembly (GO:0016226) | 4.74673363 |
| 15 | maturation of SSU-rRNA (GO:0030490) | 4.71884963 |
| 16 | regulation of cilium movement (GO:0003352) | 4.49131178 |
| 17 | chaperone-mediated protein transport (GO:0072321) | 4.44323420 |
| 18 | protein neddylation (GO:0045116) | 4.43698931 |
| 19 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.40086700 |
| 20 | respiratory electron transport chain (GO:0022904) | 4.35934826 |
| 21 | electron transport chain (GO:0022900) | 4.31943711 |
| 22 | viral transcription (GO:0019083) | 4.24377285 |
| 23 | cytolysis (GO:0019835) | 4.11840200 |
| 24 | translational termination (GO:0006415) | 4.06896607 |
| 25 | negative regulation by host of viral transcription (GO:0043922) | 3.98016042 |
| 26 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.91919389 |
| 27 | sequestering of actin monomers (GO:0042989) | 3.88367920 |
| 28 | regulation of regulatory T cell differentiation (GO:0045589) | 3.83965582 |
| 29 | translational elongation (GO:0006414) | 3.80111319 |
| 30 | positive T cell selection (GO:0043368) | 3.79627786 |
| 31 | positive thymic T cell selection (GO:0045059) | 3.75736133 |
| 32 | positive regulation of defense response to virus by host (GO:0002230) | 3.73533547 |
| 33 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.65531008 |
| 34 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.64572836 |
| 35 | actin nucleation (GO:0045010) | 3.60957822 |
| 36 | ubiquinone biosynthetic process (GO:0006744) | 3.60881715 |
| 37 | protein targeting to ER (GO:0045047) | 3.56247339 |
| 38 | ribosomal small subunit biogenesis (GO:0042274) | 3.55339690 |
| 39 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.54921740 |
| 40 | cotranslational protein targeting to membrane (GO:0006613) | 3.54690876 |
| 41 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.45973777 |
| 42 | response to pheromone (GO:0019236) | 3.44158991 |
| 43 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.42365752 |
| 44 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.42365752 |
| 45 | protein localization to endoplasmic reticulum (GO:0070972) | 3.42185912 |
| 46 | termination of RNA polymerase III transcription (GO:0006386) | 3.39938381 |
| 47 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.39938381 |
| 48 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.35106419 |
| 49 | ubiquinone metabolic process (GO:0006743) | 3.26109355 |
| 50 | hydrogen ion transmembrane transport (GO:1902600) | 3.25052039 |
| 51 | positive regulation of T cell apoptotic process (GO:0070234) | 3.23400430 |
| 52 | negative regulation of viral genome replication (GO:0045071) | 3.21760910 |
| 53 | indolalkylamine metabolic process (GO:0006586) | 3.18669699 |
| 54 | DNA demethylation (GO:0080111) | 3.18183596 |
| 55 | epithelial cilium movement (GO:0003351) | 3.14052183 |
| 56 | cellular protein complex disassembly (GO:0043624) | 3.13342380 |
| 57 | positive regulation of tolerance induction (GO:0002645) | 3.05967741 |
| 58 | viral life cycle (GO:0019058) | 2.98029802 |
| 59 | piRNA metabolic process (GO:0034587) | 2.91774476 |
| 60 | proton transport (GO:0015992) | 2.91589560 |
| 61 | DNA dealkylation (GO:0035510) | 2.90990800 |
| 62 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.90661845 |
| 63 | ATP biosynthetic process (GO:0006754) | 2.90480332 |
| 64 | eosinophil chemotaxis (GO:0048245) | 2.90375598 |
| 65 | quinone biosynthetic process (GO:1901663) | 2.88471331 |
| 66 | intracellular protein transmembrane import (GO:0044743) | 2.88305647 |
| 67 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 2.88007657 |
| 68 | axonemal dynein complex assembly (GO:0070286) | 2.86606290 |
| 69 | hydrogen transport (GO:0006818) | 2.85185211 |
| 70 | respiratory chain complex IV assembly (GO:0008535) | 2.84990185 |
| 71 | regulation of microtubule-based movement (GO:0060632) | 2.84221048 |
| 72 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 2.82182998 |
| 73 | mast cell degranulation (GO:0043303) | 2.81477315 |
| 74 | mast cell activation involved in immune response (GO:0002279) | 2.81477315 |
| 75 | pseudouridine synthesis (GO:0001522) | 2.80278300 |
| 76 | positive regulation of gamma-delta T cell activation (GO:0046645) | 2.80173989 |
| 77 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.79448690 |
| 78 | negative regulation of viral transcription (GO:0032897) | 2.78608521 |
| 79 | pyrimidine-containing compound catabolic process (GO:0072529) | 2.78167953 |
| 80 | negative regulation of T cell apoptotic process (GO:0070233) | 2.78007446 |
| 81 | nonmotile primary cilium assembly (GO:0035058) | 2.75134923 |
| 82 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.75024641 |
| 83 | cytochrome complex assembly (GO:0017004) | 2.74539452 |
| 84 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.73884571 |
| 85 | platelet dense granule organization (GO:0060155) | 2.73622486 |
| 86 | protein complex biogenesis (GO:0070271) | 2.71069488 |
| 87 | regulation of interleukin-8 secretion (GO:2000482) | 2.70635851 |
| 88 | translation (GO:0006412) | 2.70406502 |
| 89 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.70199657 |
| 90 | inner mitochondrial membrane organization (GO:0007007) | 2.68252787 |
| 91 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.66126718 |
| 92 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.65719371 |
| 93 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.65719371 |
| 94 | regulation of T cell tolerance induction (GO:0002664) | 2.64821114 |
| 95 | eosinophil migration (GO:0072677) | 2.64208996 |
| 96 | behavioral response to nicotine (GO:0035095) | 2.63500931 |
| 97 | regulation of defense response to virus by host (GO:0050691) | 2.62433323 |
| 98 | cellular response to interleukin-15 (GO:0071350) | 2.61765612 |
| 99 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.60805534 |
| 100 | positive regulation of lymphocyte apoptotic process (GO:0070230) | 2.60310730 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 6.48600011 |
| 2 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 4.79161775 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.31938232 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.24411497 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.23571336 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.12715381 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.09140069 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.96963177 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.92986113 |
| 10 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.86596824 |
| 11 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.75044442 |
| 12 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61055376 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.53051069 |
| 14 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.48723088 |
| 15 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.27698264 |
| 16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.25420805 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.13211641 |
| 18 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.07751571 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.99139993 |
| 20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.98998917 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.84358608 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.75807856 |
| 23 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.73920787 |
| 24 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.57989225 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.56179121 |
| 26 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.55896025 |
| 27 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.54475097 |
| 28 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.52187032 |
| 29 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.52187032 |
| 30 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.49309773 |
| 31 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.47921907 |
| 32 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.47446535 |
| 33 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.47273632 |
| 34 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.46034851 |
| 35 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.45812990 |
| 36 | AR_20517297_ChIP-Seq_VCAP_Human | 1.44429042 |
| 37 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.43001168 |
| 38 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.41346690 |
| 39 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.33976937 |
| 40 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.33917965 |
| 41 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.33898156 |
| 42 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.32437642 |
| 43 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.32323266 |
| 44 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.27995346 |
| 45 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.24602785 |
| 46 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.24602365 |
| 47 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.22275703 |
| 48 | ERA_21632823_ChIP-Seq_H3396_Human | 1.21975499 |
| 49 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.21697302 |
| 50 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19689431 |
| 51 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19216111 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.16313883 |
| 53 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.15728070 |
| 54 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.15196663 |
| 55 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.14442416 |
| 56 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.13442293 |
| 57 | GATA3_26560356_Chip-Seq_TH2_Human | 1.11967040 |
| 58 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.11808189 |
| 59 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.09088152 |
| 60 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 1.08229664 |
| 61 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08193365 |
| 62 | MYB_26560356_Chip-Seq_TH2_Human | 1.07739199 |
| 63 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.06741707 |
| 64 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.05032120 |
| 65 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.04344042 |
| 66 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 1.02744820 |
| 67 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.02414250 |
| 68 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 1.02082433 |
| 69 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.00347488 |
| 70 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.99444617 |
| 71 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.98723361 |
| 72 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.98276881 |
| 73 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.98131142 |
| 74 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.97668313 |
| 75 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.97246480 |
| 76 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.96955958 |
| 77 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.96520940 |
| 78 | P300_27268052_Chip-Seq_Bcells_Human | 0.96070767 |
| 79 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95931275 |
| 80 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.94495823 |
| 81 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.94176818 |
| 82 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.93849236 |
| 83 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.93650489 |
| 84 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.93650489 |
| 85 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.93310053 |
| 86 | EWS_26573619_Chip-Seq_HEK293_Human | 0.92153106 |
| 87 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.91922406 |
| 88 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.91570911 |
| 89 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 0.91175510 |
| 90 | SA1_27219007_Chip-Seq_Bcells_Human | 0.91135226 |
| 91 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.90708960 |
| 92 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.90708960 |
| 93 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.89719479 |
| 94 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.89595994 |
| 95 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.89153382 |
| 96 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.89026048 |
| 97 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.89022255 |
| 98 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.88649288 |
| 99 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.87861445 |
| 100 | TTF2_22483619_ChIP-Seq_HELA_Human | 0.87850993 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.11012136 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.23080342 |
| 3 | MP0002638_abnormal_pupillary_reflex | 2.66142646 |
| 4 | MP0003787_abnormal_imprinting | 2.48760804 |
| 5 | MP0006082_CNS_inflammation | 2.40744039 |
| 6 | MP0005646_abnormal_pituitary_gland | 2.40584718 |
| 7 | MP0003878_abnormal_ear_physiology | 2.37057087 |
| 8 | MP0005377_hearing/vestibular/ear_phenot | 2.37057087 |
| 9 | MP0001529_abnormal_vocalization | 2.25283653 |
| 10 | MP0006292_abnormal_olfactory_placode | 2.20150352 |
| 11 | MP0009785_altered_susceptibility_to | 2.13644949 |
| 12 | MP0003195_calcinosis | 2.10545919 |
| 13 | MP0003123_paternal_imprinting | 2.00309581 |
| 14 | MP0001485_abnormal_pinna_reflex | 1.88389646 |
| 15 | MP0009333_abnormal_splenocyte_physiolog | 1.88029503 |
| 16 | MP0006072_abnormal_retinal_apoptosis | 1.84429172 |
| 17 | MP0002148_abnormal_hypersensitivity_rea | 1.81638299 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.76218253 |
| 19 | MP0001968_abnormal_touch/_nociception | 1.73743738 |
| 20 | MP0002163_abnormal_gland_morphology | 1.66637535 |
| 21 | MP0003866_abnormal_defecation | 1.65448430 |
| 22 | MP0002102_abnormal_ear_morphology | 1.65097774 |
| 23 | MP0008872_abnormal_physiological_respon | 1.63675168 |
| 24 | MP0001905_abnormal_dopamine_level | 1.63302386 |
| 25 | MP0005000_abnormal_immune_tolerance | 1.56102714 |
| 26 | MP0004885_abnormal_endolymph | 1.54948000 |
| 27 | MP0006276_abnormal_autonomic_nervous | 1.54128766 |
| 28 | MP0003724_increased_susceptibility_to | 1.51998116 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.51925943 |
| 30 | MP0002277_abnormal_respiratory_mucosa | 1.50604063 |
| 31 | MP0001835_abnormal_antigen_presentation | 1.48425569 |
| 32 | MP0008875_abnormal_xenobiotic_pharmacok | 1.48235650 |
| 33 | MP0005645_abnormal_hypothalamus_physiol | 1.45139343 |
| 34 | MP0002876_abnormal_thyroid_physiology | 1.43170149 |
| 35 | MP0001986_abnormal_taste_sensitivity | 1.42913162 |
| 36 | MP0005025_abnormal_response_to | 1.39714167 |
| 37 | MP0001800_abnormal_humoral_immune | 1.35428820 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.33900608 |
| 39 | MP0006035_abnormal_mitochondrial_morpho | 1.33817679 |
| 40 | MP0002736_abnormal_nociception_after | 1.31984154 |
| 41 | MP0002723_abnormal_immune_serum | 1.31335602 |
| 42 | MP0005253_abnormal_eye_physiology | 1.31198762 |
| 43 | MP0001873_stomach_inflammation | 1.30255747 |
| 44 | MP0002420_abnormal_adaptive_immunity | 1.28587293 |
| 45 | MP0008789_abnormal_olfactory_epithelium | 1.28068823 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 1.27596485 |
| 47 | MP0005389_reproductive_system_phenotype | 1.26882666 |
| 48 | MP0001819_abnormal_immune_cell | 1.26070725 |
| 49 | MP0001984_abnormal_olfaction | 1.23609546 |
| 50 | MP0002837_dystrophic_cardiac_calcinosis | 1.23547043 |
| 51 | MP0001764_abnormal_homeostasis | 1.22765629 |
| 52 | MP0010155_abnormal_intestine_physiology | 1.22143640 |
| 53 | MP0002138_abnormal_hepatobiliary_system | 1.21030098 |
| 54 | MP0004742_abnormal_vestibular_system | 1.18349652 |
| 55 | MP0009764_decreased_sensitivity_to | 1.17745150 |
| 56 | MP0003879_abnormal_hair_cell | 1.16970086 |
| 57 | MP0000372_irregular_coat_pigmentation | 1.16601069 |
| 58 | MP0002160_abnormal_reproductive_system | 1.13373517 |
| 59 | MP0005379_endocrine/exocrine_gland_phen | 1.11534886 |
| 60 | MP0005083_abnormal_biliary_tract | 1.08800862 |
| 61 | MP0006036_abnormal_mitochondrial_physio | 1.07752619 |
| 62 | MP0005387_immune_system_phenotype | 1.03876547 |
| 63 | MP0001790_abnormal_immune_system | 1.03876547 |
| 64 | MP0001970_abnormal_pain_threshold | 1.02178323 |
| 65 | MP0003011_delayed_dark_adaptation | 1.00000004 |
| 66 | MP0002254_reproductive_system_inflammat | 0.99303463 |
| 67 | MP0002452_abnormal_antigen_presenting | 0.99275416 |
| 68 | MP0005410_abnormal_fertilization | 0.99089175 |
| 69 | MP0001765_abnormal_ion_homeostasis | 0.98248705 |
| 70 | MP0002735_abnormal_chemical_nociception | 0.98220057 |
| 71 | MP0005085_abnormal_gallbladder_physiolo | 0.97161908 |
| 72 | MP0003136_yellow_coat_color | 0.96639967 |
| 73 | MP0000716_abnormal_immune_system | 0.96112548 |
| 74 | MP0004142_abnormal_muscle_tone | 0.95721019 |
| 75 | MP0000631_abnormal_neuroendocrine_gland | 0.93875357 |
| 76 | MP0002933_joint_inflammation | 0.92453239 |
| 77 | MP0002272_abnormal_nervous_system | 0.91408617 |
| 78 | MP0004130_abnormal_muscle_cell | 0.91339411 |
| 79 | MP0001919_abnormal_reproductive_system | 0.91160909 |
| 80 | MP0001293_anophthalmia | 0.90885647 |
| 81 | MP0005499_abnormal_olfactory_system | 0.89524885 |
| 82 | MP0005394_taste/olfaction_phenotype | 0.89524885 |
| 83 | MP0004147_increased_porphyrin_level | 0.88742332 |
| 84 | MP0002733_abnormal_thermal_nociception | 0.87871332 |
| 85 | MP0002734_abnormal_mechanical_nocicepti | 0.87012183 |
| 86 | MP0003119_abnormal_digestive_system | 0.86850831 |
| 87 | MP0001845_abnormal_inflammatory_respons | 0.86116769 |
| 88 | MP0009745_abnormal_behavioral_response | 0.85889549 |
| 89 | MP0003315_abnormal_perineum_morphology | 0.83963494 |
| 90 | MP0003646_muscle_fatigue | 0.82417906 |
| 91 | MP0004947_skin_inflammation | 0.80241191 |
| 92 | MP0005636_abnormal_mineral_homeostasis | 0.80157286 |
| 93 | MP0002398_abnormal_bone_marrow | 0.79171133 |
| 94 | MP0002234_abnormal_pharynx_morphology | 0.78716260 |
| 95 | MP0000230_abnormal_systemic_arterial | 0.77551605 |
| 96 | MP0000689_abnormal_spleen_morphology | 0.76623875 |
| 97 | MP0003786_premature_aging | 0.75746839 |
| 98 | MP0003252_abnormal_bile_duct | 0.75517519 |
| 99 | MP0005360_urolithiasis | 0.75368041 |
| 100 | MP0002006_tumorigenesis | 0.75297487 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.29918182 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.21123848 |
| 3 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.14429164 |
| 4 | Increased intramyocellular lipid droplets (HP:0012240) | 4.04210468 |
| 5 | Acute necrotizing encephalopathy (HP:0006965) | 4.01136853 |
| 6 | Molar tooth sign on MRI (HP:0002419) | 3.97861686 |
| 7 | Abnormality of midbrain morphology (HP:0002418) | 3.97861686 |
| 8 | Pancreatic cysts (HP:0001737) | 3.92604860 |
| 9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.85414300 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.76266643 |
| 11 | Pancreatic fibrosis (HP:0100732) | 3.75269658 |
| 12 | True hermaphroditism (HP:0010459) | 3.66276566 |
| 13 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.55703849 |
| 14 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.49887270 |
| 15 | Reticulocytopenia (HP:0001896) | 3.47120649 |
| 16 | 3-Methylglutaconic aciduria (HP:0003535) | 3.43815927 |
| 17 | Increased CSF lactate (HP:0002490) | 3.41811642 |
| 18 | Acute encephalopathy (HP:0006846) | 3.40469203 |
| 19 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.34327176 |
| 20 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.34327176 |
| 21 | Increased muscle lipid content (HP:0009058) | 3.32140191 |
| 22 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.30869372 |
| 23 | Absent/shortened dynein arms (HP:0200106) | 3.30869372 |
| 24 | Increased IgM level (HP:0003496) | 3.28362343 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 3.26561673 |
| 26 | Hepatocellular necrosis (HP:0001404) | 3.14050268 |
| 27 | Progressive macrocephaly (HP:0004481) | 3.12929552 |
| 28 | IgG deficiency (HP:0004315) | 3.10042211 |
| 29 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.06789485 |
| 30 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.06789485 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.93886787 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.90328708 |
| 33 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.90066267 |
| 34 | Bile duct proliferation (HP:0001408) | 2.86397695 |
| 35 | Abnormal biliary tract physiology (HP:0012439) | 2.86397695 |
| 36 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.85104108 |
| 37 | Hepatic necrosis (HP:0002605) | 2.77778614 |
| 38 | Chronic bronchitis (HP:0004469) | 2.68978030 |
| 39 | Abnormality of T cell number (HP:0011839) | 2.68193935 |
| 40 | T lymphocytopenia (HP:0005403) | 2.62195925 |
| 41 | Exertional dyspnea (HP:0002875) | 2.59463868 |
| 42 | Decreased central vision (HP:0007663) | 2.58628211 |
| 43 | Cystic liver disease (HP:0006706) | 2.57441617 |
| 44 | Optic disc pallor (HP:0000543) | 2.56600785 |
| 45 | Macrocytic anemia (HP:0001972) | 2.55675307 |
| 46 | Severe combined immunodeficiency (HP:0004430) | 2.52602047 |
| 47 | Congenital stationary night blindness (HP:0007642) | 2.52003257 |
| 48 | Aplastic anemia (HP:0001915) | 2.50418443 |
| 49 | Cerebral edema (HP:0002181) | 2.49587460 |
| 50 | Autoimmune hemolytic anemia (HP:0001890) | 2.48521480 |
| 51 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.47584497 |
| 52 | Abnormality of renal resorption (HP:0011038) | 2.46482196 |
| 53 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.40499236 |
| 54 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.29687881 |
| 55 | Sclerocornea (HP:0000647) | 2.25144663 |
| 56 | Abnormal ciliary motility (HP:0012262) | 2.23702316 |
| 57 | Increased serum lactate (HP:0002151) | 2.22573555 |
| 58 | Respiratory difficulties (HP:0002880) | 2.21862856 |
| 59 | Colon cancer (HP:0003003) | 2.12144618 |
| 60 | Lactic acidosis (HP:0003128) | 2.11808641 |
| 61 | Bronchiectasis (HP:0002110) | 2.08113237 |
| 62 | Abnormality of eosinophils (HP:0001879) | 2.06685992 |
| 63 | Hypomagnesemia (HP:0002917) | 2.06064003 |
| 64 | Chronic hepatic failure (HP:0100626) | 2.03335066 |
| 65 | Exercise intolerance (HP:0003546) | 2.03220304 |
| 66 | Pallor (HP:0000980) | 2.02853556 |
| 67 | Attenuation of retinal blood vessels (HP:0007843) | 1.98809844 |
| 68 | Hypoplasia of the uterus (HP:0000013) | 1.97027618 |
| 69 | Chronic sinusitis (HP:0011109) | 1.95232658 |
| 70 | Bronchitis (HP:0012387) | 1.94668215 |
| 71 | Anencephaly (HP:0002323) | 1.94432005 |
| 72 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.93039582 |
| 73 | Pendular nystagmus (HP:0012043) | 1.92865524 |
| 74 | Rhinitis (HP:0012384) | 1.91480526 |
| 75 | Nephronophthisis (HP:0000090) | 1.91119142 |
| 76 | Medial flaring of the eyebrow (HP:0010747) | 1.91032130 |
| 77 | Stenosis of the external auditory canal (HP:0000402) | 1.90110152 |
| 78 | Combined immunodeficiency (HP:0005387) | 1.90029936 |
| 79 | Hypergammaglobulinemia (HP:0010702) | 1.89034666 |
| 80 | Supernumerary spleens (HP:0009799) | 1.87187048 |
| 81 | Brushfield spots (HP:0001088) | 1.86463751 |
| 82 | Abnormality of magnesium homeostasis (HP:0004921) | 1.86040188 |
| 83 | Oligomenorrhea (HP:0000876) | 1.85724020 |
| 84 | Abnormality of T cells (HP:0002843) | 1.81520757 |
| 85 | Hyperphosphaturia (HP:0003109) | 1.80993665 |
| 86 | Eosinophilia (HP:0001880) | 1.80287562 |
| 87 | Respiratory failure (HP:0002878) | 1.79149914 |
| 88 | Male pseudohermaphroditism (HP:0000037) | 1.78571309 |
| 89 | Abnormality of DNA repair (HP:0003254) | 1.78288367 |
| 90 | Hypoplasia of the pons (HP:0012110) | 1.77197442 |
| 91 | Abnormality of urine glucose concentration (HP:0011016) | 1.77070308 |
| 92 | Glycosuria (HP:0003076) | 1.77070308 |
| 93 | Abnormality of the pons (HP:0007361) | 1.76846314 |
| 94 | Abnormality of the renal collecting system (HP:0004742) | 1.76066596 |
| 95 | Recurrent otitis media (HP:0000403) | 1.75223351 |
| 96 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.74875933 |
| 97 | Abolished electroretinogram (ERG) (HP:0000550) | 1.74074825 |
| 98 | Type II lissencephaly (HP:0007260) | 1.72150873 |
| 99 | Erythema (HP:0010783) | 1.71347873 |
| 100 | Cerebral palsy (HP:0100021) | 1.70039827 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 6.42309794 |
| 2 | TLK1 | 4.87939971 |
| 3 | KDR | 3.59599897 |
| 4 | VRK2 | 3.46779695 |
| 5 | TESK2 | 3.10681889 |
| 6 | WNK3 | 2.57587200 |
| 7 | BCKDK | 2.50868062 |
| 8 | SIK2 | 2.45355774 |
| 9 | VRK1 | 2.41546646 |
| 10 | TIE1 | 2.39951763 |
| 11 | STK16 | 2.13019269 |
| 12 | ADRBK2 | 2.05570311 |
| 13 | LIMK1 | 2.01294430 |
| 14 | WNK4 | 1.92778841 |
| 15 | MAP4K2 | 1.82624701 |
| 16 | TRIM28 | 1.77818580 |
| 17 | TXK | 1.75057086 |
| 18 | GRK1 | 1.74452622 |
| 19 | PIK3CA | 1.68433769 |
| 20 | MAP4K1 | 1.56819821 |
| 21 | TNIK | 1.49351084 |
| 22 | TESK1 | 1.48621763 |
| 23 | BUB1 | 1.42106565 |
| 24 | MAP2K7 | 1.38065694 |
| 25 | CASK | 1.30138081 |
| 26 | FRK | 1.26878492 |
| 27 | BMPR1B | 1.26115139 |
| 28 | TNK2 | 1.25302187 |
| 29 | MAP3K12 | 1.24218072 |
| 30 | NEK2 | 1.14956328 |
| 31 | ITK | 1.11672674 |
| 32 | TAOK3 | 1.09253230 |
| 33 | MAP3K11 | 1.04611457 |
| 34 | MAP3K4 | 1.03989999 |
| 35 | SRPK1 | 1.03548722 |
| 36 | DAPK1 | 0.98508779 |
| 37 | DAPK2 | 0.97415497 |
| 38 | PLK2 | 0.94819404 |
| 39 | PRKCQ | 0.94080415 |
| 40 | PIM2 | 0.92323268 |
| 41 | NUAK1 | 0.89340323 |
| 42 | ZAP70 | 0.86841625 |
| 43 | IKBKB | 0.80870798 |
| 44 | GRK7 | 0.75767467 |
| 45 | DYRK2 | 0.75341901 |
| 46 | MARK3 | 0.74411557 |
| 47 | PIM1 | 0.73476996 |
| 48 | PAK6 | 0.71221617 |
| 49 | RPS6KA5 | 0.70496151 |
| 50 | PLK3 | 0.69975527 |
| 51 | CSNK1G3 | 0.68599250 |
| 52 | CSNK1G2 | 0.64968577 |
| 53 | PINK1 | 0.64461003 |
| 54 | BCR | 0.63594923 |
| 55 | MST4 | 0.62617306 |
| 56 | TEC | 0.62562283 |
| 57 | LCK | 0.61959054 |
| 58 | MAPK13 | 0.60175323 |
| 59 | PLK4 | 0.58799260 |
| 60 | DAPK3 | 0.57506689 |
| 61 | EPHB2 | 0.55918744 |
| 62 | ADRBK1 | 0.54353170 |
| 63 | SYK | 0.53578764 |
| 64 | SCYL2 | 0.52658053 |
| 65 | INSRR | 0.50867669 |
| 66 | CSNK1A1L | 0.50017645 |
| 67 | LYN | 0.49499585 |
| 68 | MAP2K6 | 0.49223903 |
| 69 | CDC7 | 0.47871626 |
| 70 | PASK | 0.47409807 |
| 71 | CSNK1G1 | 0.45347276 |
| 72 | MYLK | 0.44225529 |
| 73 | ACVR1B | 0.43297550 |
| 74 | PIK3CG | 0.42358364 |
| 75 | KIT | 0.41903118 |
| 76 | TTK | 0.41541658 |
| 77 | MAP3K5 | 0.41169198 |
| 78 | BRAF | 0.40682890 |
| 79 | PRKD3 | 0.39148440 |
| 80 | PRKCE | 0.38915698 |
| 81 | AKT3 | 0.38116566 |
| 82 | CSF1R | 0.37078097 |
| 83 | PRKCA | 0.36472594 |
| 84 | ROCK1 | 0.36459289 |
| 85 | CDK8 | 0.34823409 |
| 86 | PRKCG | 0.34599508 |
| 87 | PKN1 | 0.33809282 |
| 88 | CSNK2A1 | 0.32720912 |
| 89 | PLK1 | 0.32439993 |
| 90 | OBSCN | 0.29831342 |
| 91 | FES | 0.29770793 |
| 92 | CSNK1A1 | 0.29394882 |
| 93 | AURKA | 0.29373865 |
| 94 | PRKACA | 0.28852879 |
| 95 | JAK3 | 0.28778222 |
| 96 | MINK1 | 0.28734128 |
| 97 | SIK3 | 0.27977884 |
| 98 | NTRK2 | 0.27785124 |
| 99 | CSNK2A2 | 0.27774392 |
| 100 | PRKCD | 0.27299480 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.54420624 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.27687905 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.90432782 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.78272984 |
| 5 | Proteasome_Homo sapiens_hsa03050 | 3.69498020 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.77813707 |
| 7 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.70781503 |
| 8 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.65169506 |
| 9 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.50156554 |
| 10 | Huntingtons disease_Homo sapiens_hsa05016 | 2.49343084 |
| 11 | Alzheimers disease_Homo sapiens_hsa05010 | 2.47390432 |
| 12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.38727819 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.33034942 |
| 14 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.32041326 |
| 15 | Allograft rejection_Homo sapiens_hsa05330 | 1.77550343 |
| 16 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.69463188 |
| 17 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.67027642 |
| 18 | Peroxisome_Homo sapiens_hsa04146 | 1.62579386 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.62320020 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.60772918 |
| 21 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.59543225 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.58082438 |
| 23 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.50688810 |
| 24 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.44058026 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.43822814 |
| 26 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.40626038 |
| 27 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.35280438 |
| 28 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.28766618 |
| 29 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.22062246 |
| 30 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.13025195 |
| 31 | Homologous recombination_Homo sapiens_hsa03440 | 1.11871561 |
| 32 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.02949433 |
| 33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.95661700 |
| 34 | Protein export_Homo sapiens_hsa03060 | 0.95367308 |
| 35 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.95325188 |
| 36 | Salmonella infection_Homo sapiens_hsa05132 | 0.93165995 |
| 37 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.87823979 |
| 38 | Malaria_Homo sapiens_hsa05144 | 0.83585085 |
| 39 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.80585656 |
| 40 | Retinol metabolism_Homo sapiens_hsa00830 | 0.79580399 |
| 41 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.78957560 |
| 42 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.77791495 |
| 43 | RNA degradation_Homo sapiens_hsa03018 | 0.77457640 |
| 44 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.73564870 |
| 45 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.73210071 |
| 46 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.72281711 |
| 47 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72224195 |
| 48 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.71163503 |
| 49 | ABC transporters_Homo sapiens_hsa02010 | 0.71056983 |
| 50 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.67686681 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.67025323 |
| 52 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64175026 |
| 53 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.61737396 |
| 54 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.61162501 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.59860107 |
| 56 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.59731194 |
| 57 | Mineral absorption_Homo sapiens_hsa04978 | 0.59287953 |
| 58 | Asthma_Homo sapiens_hsa05310 | 0.58749798 |
| 59 | Nicotine addiction_Homo sapiens_hsa05033 | 0.58188318 |
| 60 | Purine metabolism_Homo sapiens_hsa00230 | 0.58017247 |
| 61 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.57124898 |
| 62 | Spliceosome_Homo sapiens_hsa03040 | 0.56788479 |
| 63 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.56576186 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56367291 |
| 65 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.56126741 |
| 66 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55111263 |
| 67 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.52748426 |
| 68 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.52446501 |
| 69 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.51251150 |
| 70 | Measles_Homo sapiens_hsa05162 | 0.50306055 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47205327 |
| 72 | Basal transcription factors_Homo sapiens_hsa03022 | 0.45365725 |
| 73 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.42744724 |
| 74 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.42386039 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.42197180 |
| 76 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.41802382 |
| 77 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.41777573 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.40531402 |
| 79 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.39630645 |
| 80 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.37839721 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.36035686 |
| 82 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.35792730 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.35471997 |
| 84 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.32698698 |
| 85 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.30660139 |
| 86 | Shigellosis_Homo sapiens_hsa05131 | 0.28716224 |
| 87 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.27499957 |
| 88 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.27490525 |
| 89 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.27391925 |
| 90 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.26585922 |
| 91 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.26239489 |
| 92 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.26203865 |
| 93 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.23140825 |
| 94 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.22083435 |
| 95 | Taste transduction_Homo sapiens_hsa04742 | 0.22038995 |
| 96 | Morphine addiction_Homo sapiens_hsa05032 | 0.18621524 |
| 97 | RNA transport_Homo sapiens_hsa03013 | 0.18170179 |
| 98 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.18037794 |
| 99 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.16145824 |
| 100 | Mismatch repair_Homo sapiens_hsa03430 | 0.14830895 |

