

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 8.36001607 |
| 2 | translational termination (GO:0006415) | 8.06632984 |
| 3 | ribosomal small subunit assembly (GO:0000028) | 7.38135201 |
| 4 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.63095714 |
| 5 | protein targeting to ER (GO:0045047) | 6.53386722 |
| 6 | cotranslational protein targeting to membrane (GO:0006613) | 6.49460268 |
| 7 | chaperone-mediated protein transport (GO:0072321) | 6.42873306 |
| 8 | translational elongation (GO:0006414) | 6.37455794 |
| 9 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 6.25391891 |
| 10 | protein localization to endoplasmic reticulum (GO:0070972) | 6.15181515 |
| 11 | ATP synthesis coupled proton transport (GO:0015986) | 6.09475824 |
| 12 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 6.09475824 |
| 13 | cellular protein complex disassembly (GO:0043624) | 6.05982304 |
| 14 | viral life cycle (GO:0019058) | 6.02484925 |
| 15 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.77660987 |
| 16 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.70701244 |
| 17 | behavioral response to nicotine (GO:0035095) | 5.69476368 |
| 18 | ribosomal small subunit biogenesis (GO:0042274) | 5.66759572 |
| 19 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 5.64320827 |
| 20 | maturation of SSU-rRNA (GO:0030490) | 5.55413181 |
| 21 | translational initiation (GO:0006413) | 5.14550386 |
| 22 | protein complex disassembly (GO:0043241) | 5.13446444 |
| 23 | preassembly of GPI anchor in ER membrane (GO:0016254) | 5.05731057 |
| 24 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.99249567 |
| 25 | pyrimidine nucleotide catabolic process (GO:0006244) | 4.98497048 |
| 26 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 4.84725496 |
| 27 | macromolecular complex disassembly (GO:0032984) | 4.76218127 |
| 28 | protein targeting to membrane (GO:0006612) | 4.47615595 |
| 29 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.31776143 |
| 30 | base-excision repair, AP site formation (GO:0006285) | 4.17852012 |
| 31 | electron transport chain (GO:0022900) | 3.97018102 |
| 32 | ribosomal large subunit biogenesis (GO:0042273) | 3.91037674 |
| 33 | respiratory electron transport chain (GO:0022904) | 3.89812277 |
| 34 | protein complex biogenesis (GO:0070271) | 3.81213917 |
| 35 | protein neddylation (GO:0045116) | 3.80433381 |
| 36 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.79237084 |
| 37 | translation (GO:0006412) | 3.73202974 |
| 38 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.70968971 |
| 39 | ATP biosynthetic process (GO:0006754) | 3.64825550 |
| 40 | GPI anchor biosynthetic process (GO:0006506) | 3.61087884 |
| 41 | GPI anchor metabolic process (GO:0006505) | 3.58021152 |
| 42 | mRNA catabolic process (GO:0006402) | 3.50574899 |
| 43 | deoxyribose phosphate catabolic process (GO:0046386) | 3.50362657 |
| 44 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.43334830 |
| 45 | deoxyribonucleotide catabolic process (GO:0009264) | 3.37128909 |
| 46 | neuronal action potential propagation (GO:0019227) | 3.36014297 |
| 47 | receptor guanylyl cyclase signaling pathway (GO:0007168) | 3.35483709 |
| 48 | pyrimidine nucleobase catabolic process (GO:0006208) | 3.30702339 |
| 49 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.25580195 |
| 50 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 3.24997359 |
| 51 | hydrogen ion transmembrane transport (GO:1902600) | 3.23612446 |
| 52 | intracellular protein transmembrane import (GO:0044743) | 3.22868853 |
| 53 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.22301053 |
| 54 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.22057240 |
| 55 | protein polyglutamylation (GO:0018095) | 3.21359574 |
| 56 | negative regulation of heart rate (GO:0010459) | 3.20966104 |
| 57 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.19798262 |
| 58 | RNA catabolic process (GO:0006401) | 3.12705422 |
| 59 | establishment of protein localization to membrane (GO:0090150) | 3.12385734 |
| 60 | NADH dehydrogenase complex assembly (GO:0010257) | 3.04251658 |
| 61 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.04251658 |
| 62 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.04251658 |
| 63 | response to pheromone (GO:0019236) | 3.01570671 |
| 64 | C-terminal protein lipidation (GO:0006501) | 2.97623742 |
| 65 | axonemal dynein complex assembly (GO:0070286) | 2.96743161 |
| 66 | negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244) | 2.94965116 |
| 67 | regulation of microtubule-based movement (GO:0060632) | 2.93894201 |
| 68 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.89729317 |
| 69 | male meiosis I (GO:0007141) | 2.88742901 |
| 70 | protein targeting (GO:0006605) | 2.87942893 |
| 71 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.87474628 |
| 72 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.87474628 |
| 73 | response to redox state (GO:0051775) | 2.86945885 |
| 74 | epithelial cilium movement (GO:0003351) | 2.84809306 |
| 75 | proton transport (GO:0015992) | 2.83229861 |
| 76 | regulation of hypersensitivity (GO:0002883) | 2.79904947 |
| 77 | motile cilium assembly (GO:0044458) | 2.79184298 |
| 78 | cell proliferation in forebrain (GO:0021846) | 2.76691620 |
| 79 | hydrogen transport (GO:0006818) | 2.75677016 |
| 80 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.72775175 |
| 81 | nucleobase catabolic process (GO:0046113) | 2.71291384 |
| 82 | fatty acid transmembrane transport (GO:1902001) | 2.69134698 |
| 83 | cellular component biogenesis (GO:0044085) | 2.66547157 |
| 84 | kynurenine metabolic process (GO:0070189) | 2.63955797 |
| 85 | negative regulation of response to food (GO:0032096) | 2.60975517 |
| 86 | negative regulation of appetite (GO:0032099) | 2.60975517 |
| 87 | intracellular protein transmembrane transport (GO:0065002) | 2.60839064 |
| 88 | positive regulation of vesicle fusion (GO:0031340) | 2.59946768 |
| 89 | platelet dense granule organization (GO:0060155) | 2.57772394 |
| 90 | somite development (GO:0061053) | 2.57198917 |
| 91 | establishment of protein localization to organelle (GO:0072594) | 2.56957618 |
| 92 | intraciliary transport (GO:0042073) | 2.54155467 |
| 93 | positive regulation of protein homodimerization activity (GO:0090073) | 2.52926069 |
| 94 | protein localization to membrane (GO:0072657) | 2.51214206 |
| 95 | head development (GO:0060322) | 2.48561983 |
| 96 | regulation of cilium movement (GO:0003352) | 2.47583601 |
| 97 | regulation of sequestering of triglyceride (GO:0010889) | 2.46274831 |
| 98 | regulation of action potential (GO:0098900) | 2.46047012 |
| 99 | synaptic transmission, cholinergic (GO:0007271) | 2.45353221 |
| 100 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.44471592 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.90983536 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.10272990 |
| 3 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.89940480 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.84379247 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.19810695 |
| 6 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.18650053 |
| 7 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.18326628 |
| 8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.17158491 |
| 9 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.11748944 |
| 10 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.06529414 |
| 11 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.03752735 |
| 12 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.02120652 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.98095980 |
| 14 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.90219910 |
| 15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.89698666 |
| 16 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.84890139 |
| 17 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.83061652 |
| 18 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.80397241 |
| 19 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.79260427 |
| 20 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.77808093 |
| 21 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.63288122 |
| 22 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.60062246 |
| 23 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.59029252 |
| 24 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.58496443 |
| 25 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.53400736 |
| 26 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.51754264 |
| 27 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.48325409 |
| 28 | RAC3_21632823_ChIP-Seq_H3396_Human | 1.47789583 |
| 29 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.47764217 |
| 30 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.47381510 |
| 31 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.45458468 |
| 32 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.45458468 |
| 33 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.44713655 |
| 34 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.44647603 |
| 35 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.44516913 |
| 36 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.41280877 |
| 37 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.40015420 |
| 38 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.39980007 |
| 39 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.39179261 |
| 40 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.37225884 |
| 41 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.35958314 |
| 42 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.34719894 |
| 43 | ERA_21632823_ChIP-Seq_H3396_Human | 1.33694846 |
| 44 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.32998382 |
| 45 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.30020299 |
| 46 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.29596428 |
| 47 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.29331184 |
| 48 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.29258496 |
| 49 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.25225646 |
| 50 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.24018600 |
| 51 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.23949426 |
| 52 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.23856897 |
| 53 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.23490261 |
| 54 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.23365251 |
| 55 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.22870010 |
| 56 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.22443265 |
| 57 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.21476842 |
| 58 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.18579271 |
| 59 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.17944176 |
| 60 | OCT4_20526341_ChIP-Seq_ESCs_Human | 1.15177293 |
| 61 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.14937724 |
| 62 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.13118761 |
| 63 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.12315493 |
| 64 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11545942 |
| 65 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.10651472 |
| 66 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.10173551 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.10120588 |
| 68 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.10069592 |
| 69 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.09315006 |
| 70 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.06902543 |
| 71 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.06014191 |
| 72 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.04803959 |
| 73 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.03685071 |
| 74 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.02014189 |
| 75 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.00988240 |
| 76 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.00852065 |
| 77 | GATA3_21867929_ChIP-Seq_TH1_Mouse | 1.00619557 |
| 78 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.99960748 |
| 79 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.99960748 |
| 80 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.98997976 |
| 81 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.98941382 |
| 82 | P300_27268052_Chip-Seq_Bcells_Human | 0.98317436 |
| 83 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.97379255 |
| 84 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.97134046 |
| 85 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.96055907 |
| 86 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.95383611 |
| 87 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.94604183 |
| 88 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 0.93580210 |
| 89 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.93429000 |
| 90 | FUS_26573619_Chip-Seq_HEK293_Human | 0.93274715 |
| 91 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.93146390 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.92507185 |
| 93 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.92030124 |
| 94 | P300_19829295_ChIP-Seq_ESCs_Human | 0.91384486 |
| 95 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.90838952 |
| 96 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.90224065 |
| 97 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.90027227 |
| 98 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.89463739 |
| 99 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.89269155 |
| 100 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.89058078 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 6.31912543 |
| 2 | MP0003646_muscle_fatigue | 5.53646826 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.83086969 |
| 4 | MP0003122_maternal_imprinting | 3.46929773 |
| 5 | MP0008789_abnormal_olfactory_epithelium | 2.99199754 |
| 6 | MP0002837_dystrophic_cardiac_calcinosis | 2.42203077 |
| 7 | MP0005646_abnormal_pituitary_gland | 2.38597485 |
| 8 | MP0003121_genomic_imprinting | 2.34109510 |
| 9 | MP0005394_taste/olfaction_phenotype | 2.27409546 |
| 10 | MP0005499_abnormal_olfactory_system | 2.27409546 |
| 11 | MP0004142_abnormal_muscle_tone | 2.17403634 |
| 12 | MP0005670_abnormal_white_adipose | 2.11261202 |
| 13 | MP0003123_paternal_imprinting | 2.00891920 |
| 14 | MP0001986_abnormal_taste_sensitivity | 1.96553481 |
| 15 | MP0003011_delayed_dark_adaptation | 1.91022478 |
| 16 | MP0003787_abnormal_imprinting | 1.75942317 |
| 17 | MP0004133_heterotaxia | 1.74778780 |
| 18 | MP0004885_abnormal_endolymph | 1.74144239 |
| 19 | MP0002102_abnormal_ear_morphology | 1.70695966 |
| 20 | MP0002736_abnormal_nociception_after | 1.68750361 |
| 21 | MP0008877_abnormal_DNA_methylation | 1.56789985 |
| 22 | MP0000631_abnormal_neuroendocrine_gland | 1.56682509 |
| 23 | MP0001968_abnormal_touch/_nociception | 1.47485951 |
| 24 | MP0006276_abnormal_autonomic_nervous | 1.46189596 |
| 25 | MP0005423_abnormal_somatic_nervous | 1.44511248 |
| 26 | MP0000049_abnormal_middle_ear | 1.43918168 |
| 27 | MP0002272_abnormal_nervous_system | 1.43861410 |
| 28 | MP0001970_abnormal_pain_threshold | 1.43066554 |
| 29 | MP0005389_reproductive_system_phenotype | 1.41074324 |
| 30 | MP0009046_muscle_twitch | 1.39445845 |
| 31 | MP0008872_abnormal_physiological_respon | 1.38863593 |
| 32 | MP0004145_abnormal_muscle_electrophysio | 1.37783818 |
| 33 | MP0001486_abnormal_startle_reflex | 1.35313974 |
| 34 | MP0000230_abnormal_systemic_arterial | 1.31143340 |
| 35 | MP0005084_abnormal_gallbladder_morpholo | 1.30988834 |
| 36 | MP0001919_abnormal_reproductive_system | 1.30755338 |
| 37 | MP0005551_abnormal_eye_electrophysiolog | 1.30675085 |
| 38 | MP0003786_premature_aging | 1.29052382 |
| 39 | MP0002160_abnormal_reproductive_system | 1.28343820 |
| 40 | MP0001485_abnormal_pinna_reflex | 1.26065592 |
| 41 | MP0003136_yellow_coat_color | 1.24263537 |
| 42 | MP0008775_abnormal_heart_ventricle | 1.23445082 |
| 43 | MP0002638_abnormal_pupillary_reflex | 1.20444795 |
| 44 | MP0001293_anophthalmia | 1.20274663 |
| 45 | MP0008995_early_reproductive_senescence | 1.18928074 |
| 46 | MP0002733_abnormal_thermal_nociception | 1.18653775 |
| 47 | MP0002163_abnormal_gland_morphology | 1.14725975 |
| 48 | MP0003315_abnormal_perineum_morphology | 1.13662849 |
| 49 | MP0000778_abnormal_nervous_system | 1.12464049 |
| 50 | MP0003119_abnormal_digestive_system | 1.12362007 |
| 51 | MP0005377_hearing/vestibular/ear_phenot | 1.11568349 |
| 52 | MP0003878_abnormal_ear_physiology | 1.11568349 |
| 53 | MP0004130_abnormal_muscle_cell | 1.11416676 |
| 54 | MP0002909_abnormal_adrenal_gland | 1.09903968 |
| 55 | MP0001905_abnormal_dopamine_level | 1.09454667 |
| 56 | MP0002876_abnormal_thyroid_physiology | 1.07737726 |
| 57 | MP0001440_abnormal_grooming_behavior | 1.07611675 |
| 58 | MP0003879_abnormal_hair_cell | 1.04964788 |
| 59 | MP0002734_abnormal_mechanical_nocicepti | 1.04428410 |
| 60 | MP0002557_abnormal_social/conspecific_i | 1.03967334 |
| 61 | MP0009745_abnormal_behavioral_response | 1.00469330 |
| 62 | MP0003283_abnormal_digestive_organ | 0.99738459 |
| 63 | MP0009764_decreased_sensitivity_to | 0.99039998 |
| 64 | MP0000026_abnormal_inner_ear | 0.98384204 |
| 65 | MP0002735_abnormal_chemical_nociception | 0.97368206 |
| 66 | MP0002234_abnormal_pharynx_morphology | 0.97166730 |
| 67 | MP0002572_abnormal_emotion/affect_behav | 0.95197970 |
| 68 | MP0002938_white_spotting | 0.93491414 |
| 69 | MP0008875_abnormal_xenobiotic_pharmacok | 0.92474183 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.92014569 |
| 71 | MP0005174_abnormal_tail_pigmentation | 0.90734790 |
| 72 | MP0003880_abnormal_central_pattern | 0.89333845 |
| 73 | MP0004742_abnormal_vestibular_system | 0.88974921 |
| 74 | MP0005645_abnormal_hypothalamus_physiol | 0.88904826 |
| 75 | MP0006072_abnormal_retinal_apoptosis | 0.88331633 |
| 76 | MP0002233_abnormal_nose_morphology | 0.87908277 |
| 77 | MP0003635_abnormal_synaptic_transmissio | 0.87284578 |
| 78 | MP0001529_abnormal_vocalization | 0.86794979 |
| 79 | MP0002653_abnormal_ependyma_morphology | 0.86532148 |
| 80 | MP0001984_abnormal_olfaction | 0.85565392 |
| 81 | MP0001963_abnormal_hearing_physiology | 0.84036982 |
| 82 | MP0003890_abnormal_embryonic-extraembry | 0.82823917 |
| 83 | MP0004043_abnormal_pH_regulation | 0.81845257 |
| 84 | MP0003567_abnormal_fetal_cardiomyocyte | 0.81272154 |
| 85 | MP0000427_abnormal_hair_cycle | 0.78755888 |
| 86 | MP0000470_abnormal_stomach_morphology | 0.78670085 |
| 87 | MP0003950_abnormal_plasma_membrane | 0.78365701 |
| 88 | MP0005195_abnormal_posterior_eye | 0.78232293 |
| 89 | MP0002064_seizures | 0.78128212 |
| 90 | MP0002063_abnormal_learning/memory/cond | 0.76323647 |
| 91 | MP0000467_abnormal_esophagus_morphology | 0.74974157 |
| 92 | MP0003938_abnormal_ear_development | 0.73829782 |
| 93 | MP0002752_abnormal_somatic_nervous | 0.72677844 |
| 94 | MP0003195_calcinosis | 0.72280865 |
| 95 | MP0010030_abnormal_orbit_morphology | 0.67962056 |
| 96 | MP0004036_abnormal_muscle_relaxation | 0.67845508 |
| 97 | MP0005253_abnormal_eye_physiology | 0.67676270 |
| 98 | MP0005085_abnormal_gallbladder_physiolo | 0.66510610 |
| 99 | MP0000955_abnormal_spinal_cord | 0.66167724 |
| 100 | MP0002277_abnormal_respiratory_mucosa | 0.65720204 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Lipid accumulation in hepatocytes (HP:0006561) | 6.08481748 |
| 2 | Reticulocytopenia (HP:0001896) | 5.35070330 |
| 3 | Abnormality of cells of the erythroid lineage (HP:0012130) | 4.36088195 |
| 4 | Increased muscle lipid content (HP:0009058) | 4.29631210 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 4.14824401 |
| 6 | Macrocytic anemia (HP:0001972) | 4.05355281 |
| 7 | Supernumerary spleens (HP:0009799) | 3.50753533 |
| 8 | Renal Fanconi syndrome (HP:0001994) | 3.44231206 |
| 9 | Pallor (HP:0000980) | 3.43228790 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.38870979 |
| 11 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.35015439 |
| 12 | Absent/shortened dynein arms (HP:0200106) | 3.35015439 |
| 13 | Methylmalonic aciduria (HP:0012120) | 3.14481808 |
| 14 | Increased intramyocellular lipid droplets (HP:0012240) | 3.09363251 |
| 15 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.05994324 |
| 16 | Abnormal number of erythroid precursors (HP:0012131) | 3.02726752 |
| 17 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.00438748 |
| 18 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.00438748 |
| 19 | Colon cancer (HP:0003003) | 3.00188343 |
| 20 | Acute necrotizing encephalopathy (HP:0006965) | 2.99738349 |
| 21 | Asplenia (HP:0001746) | 2.94346084 |
| 22 | Septo-optic dysplasia (HP:0100842) | 2.90228726 |
| 23 | Absent thumb (HP:0009777) | 2.86610986 |
| 24 | Increased CSF lactate (HP:0002490) | 2.77733036 |
| 25 | Methylmalonic acidemia (HP:0002912) | 2.75066934 |
| 26 | Hip dysplasia (HP:0001385) | 2.71198901 |
| 27 | Tubulointerstitial nephritis (HP:0001970) | 2.70551766 |
| 28 | Abnormality of renal resorption (HP:0011038) | 2.70109637 |
| 29 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.68523692 |
| 30 | Abnormality of urine glucose concentration (HP:0011016) | 2.61988734 |
| 31 | Glycosuria (HP:0003076) | 2.61988734 |
| 32 | Enlarged kidneys (HP:0000105) | 2.61024045 |
| 33 | Exertional dyspnea (HP:0002875) | 2.57807535 |
| 34 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.57288394 |
| 35 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.57288394 |
| 36 | Acute encephalopathy (HP:0006846) | 2.54958443 |
| 37 | Hepatocellular necrosis (HP:0001404) | 2.54314262 |
| 38 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.53752860 |
| 39 | Dicarboxylic aciduria (HP:0003215) | 2.53752860 |
| 40 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.51383129 |
| 41 | Hyperglycinemia (HP:0002154) | 2.48036157 |
| 42 | Pancreatic fibrosis (HP:0100732) | 2.47890119 |
| 43 | Progressive macrocephaly (HP:0004481) | 2.47882409 |
| 44 | Abnormality of midbrain morphology (HP:0002418) | 2.47262804 |
| 45 | Molar tooth sign on MRI (HP:0002419) | 2.47262804 |
| 46 | Abnormal drinking behavior (HP:0030082) | 2.47077962 |
| 47 | Polydipsia (HP:0001959) | 2.47077962 |
| 48 | Nephrogenic diabetes insipidus (HP:0009806) | 2.42006916 |
| 49 | Stenosis of the external auditory canal (HP:0000402) | 2.41914541 |
| 50 | Abnormal biliary tract physiology (HP:0012439) | 2.40251024 |
| 51 | Bile duct proliferation (HP:0001408) | 2.40251024 |
| 52 | Nephronophthisis (HP:0000090) | 2.36244050 |
| 53 | Abnormal ciliary motility (HP:0012262) | 2.36113367 |
| 54 | Type II lissencephaly (HP:0007260) | 2.34831618 |
| 55 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.32876354 |
| 56 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 2.28965950 |
| 57 | Hepatic necrosis (HP:0002605) | 2.25216181 |
| 58 | Medial flaring of the eyebrow (HP:0010747) | 2.22762303 |
| 59 | Congenital stationary night blindness (HP:0007642) | 2.18759941 |
| 60 | Abnormality of the renal medulla (HP:0100957) | 2.14303777 |
| 61 | Gait imbalance (HP:0002141) | 2.13583983 |
| 62 | Congenital, generalized hypertrichosis (HP:0004540) | 2.13171739 |
| 63 | Polyphagia (HP:0002591) | 2.08487981 |
| 64 | Respiratory difficulties (HP:0002880) | 2.05498031 |
| 65 | Myokymia (HP:0002411) | 2.04756603 |
| 66 | Hyperphosphaturia (HP:0003109) | 2.04066343 |
| 67 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.01743821 |
| 68 | Agammaglobulinemia (HP:0004432) | 2.00450584 |
| 69 | Congenital primary aphakia (HP:0007707) | 2.00165967 |
| 70 | Hyperphosphatemia (HP:0002905) | 2.00100046 |
| 71 | Respiratory failure (HP:0002878) | 1.97941731 |
| 72 | Abnormal hemoglobin (HP:0011902) | 1.97657283 |
| 73 | Hypoplasia of the ulna (HP:0003022) | 1.97534105 |
| 74 | Pancreatic cysts (HP:0001737) | 1.97406154 |
| 75 | Absent septum pellucidum (HP:0001331) | 1.96230524 |
| 76 | Panhypogammaglobulinemia (HP:0003139) | 1.95946446 |
| 77 | Chronic bronchitis (HP:0004469) | 1.91361428 |
| 78 | Abnormal urine phosphate concentration (HP:0012599) | 1.90380000 |
| 79 | True hermaphroditism (HP:0010459) | 1.89805807 |
| 80 | Conjugated hyperbilirubinemia (HP:0002908) | 1.89656434 |
| 81 | Depressed nasal ridge (HP:0000457) | 1.88987117 |
| 82 | Muscle stiffness (HP:0003552) | 1.87843506 |
| 83 | Broad distal phalanx of finger (HP:0009836) | 1.83820508 |
| 84 | Ureteral duplication (HP:0000073) | 1.83077126 |
| 85 | Respiratory distress (HP:0002098) | 1.81727100 |
| 86 | Cerebral edema (HP:0002181) | 1.80582365 |
| 87 | Tubulointerstitial abnormality (HP:0001969) | 1.80568668 |
| 88 | Short femoral neck (HP:0100864) | 1.79149458 |
| 89 | Maternal diabetes (HP:0009800) | 1.78460722 |
| 90 | Abnormality of DNA repair (HP:0003254) | 1.77997315 |
| 91 | Lissencephaly (HP:0001339) | 1.75361756 |
| 92 | Hyperthyroidism (HP:0000836) | 1.73326805 |
| 93 | Optic disc pallor (HP:0000543) | 1.72329769 |
| 94 | Abnormality of the renal collecting system (HP:0004742) | 1.71429739 |
| 95 | Large eyes (HP:0001090) | 1.70426577 |
| 96 | Cystic liver disease (HP:0006706) | 1.69938034 |
| 97 | Polyuria (HP:0000103) | 1.69625407 |
| 98 | Abolished electroretinogram (ERG) (HP:0000550) | 1.67001394 |
| 99 | Tubular atrophy (HP:0000092) | 1.65864100 |
| 100 | Rib fusion (HP:0000902) | 1.65544539 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | WNK4 | 4.07086429 |
| 2 | ERN1 | 3.45623360 |
| 3 | ADRBK2 | 3.09594951 |
| 4 | DYRK2 | 2.86286173 |
| 5 | MAP2K2 | 2.52058597 |
| 6 | STK39 | 2.48901706 |
| 7 | STK16 | 2.40853762 |
| 8 | MAP3K12 | 2.34692785 |
| 9 | DAPK2 | 2.31283395 |
| 10 | GRK1 | 2.18366724 |
| 11 | TAOK3 | 2.15490529 |
| 12 | FRK | 2.15240804 |
| 13 | MAP4K2 | 2.12473554 |
| 14 | CDK19 | 2.09392504 |
| 15 | TLK1 | 2.03678499 |
| 16 | LRRK2 | 1.75645336 |
| 17 | STK11 | 1.60140576 |
| 18 | WNK1 | 1.59320354 |
| 19 | TIE1 | 1.52449198 |
| 20 | BCKDK | 1.48117702 |
| 21 | BMPR2 | 1.39180846 |
| 22 | ADRBK1 | 1.30896429 |
| 23 | ILK | 1.30209035 |
| 24 | MINK1 | 1.29824039 |
| 25 | EPHB2 | 1.28373922 |
| 26 | DAPK3 | 1.25484503 |
| 27 | MAPK13 | 1.17566239 |
| 28 | ZAK | 1.11883512 |
| 29 | PLK2 | 1.07264062 |
| 30 | BMPR1B | 1.07131414 |
| 31 | NUAK1 | 1.00379159 |
| 32 | PRKCQ | 1.00300055 |
| 33 | MYLK | 0.99552900 |
| 34 | TEC | 0.98775363 |
| 35 | MAP2K7 | 0.94695701 |
| 36 | MAPK15 | 0.93735025 |
| 37 | RPS6KA6 | 0.92363853 |
| 38 | EPHA4 | 0.90756051 |
| 39 | MAP3K11 | 0.89006764 |
| 40 | INSRR | 0.88754873 |
| 41 | SCYL2 | 0.85634465 |
| 42 | MAP3K9 | 0.81402179 |
| 43 | MAP2K1 | 0.80141720 |
| 44 | NLK | 0.77595381 |
| 45 | IKBKE | 0.77048539 |
| 46 | PINK1 | 0.76436761 |
| 47 | CAMKK1 | 0.75407166 |
| 48 | RPS6KL1 | 0.74843433 |
| 49 | RPS6KC1 | 0.74843433 |
| 50 | IKBKB | 0.74792690 |
| 51 | ROCK1 | 0.72984998 |
| 52 | PRKACA | 0.70964892 |
| 53 | MAP2K4 | 0.69827974 |
| 54 | NEK2 | 0.69623990 |
| 55 | PRKCG | 0.68834947 |
| 56 | PHKG2 | 0.68823969 |
| 57 | PHKG1 | 0.68823969 |
| 58 | NTRK2 | 0.68629445 |
| 59 | RPS6KA2 | 0.68072007 |
| 60 | WNK3 | 0.66638510 |
| 61 | RPS6KA5 | 0.66316622 |
| 62 | NEK1 | 0.65051278 |
| 63 | CSNK1G2 | 0.64035509 |
| 64 | CAMKK2 | 0.63841892 |
| 65 | MKNK2 | 0.63756545 |
| 66 | IRAK2 | 0.63727803 |
| 67 | MAP3K10 | 0.63413502 |
| 68 | CSNK1G3 | 0.63081807 |
| 69 | OBSCN | 0.61258734 |
| 70 | CAMK1 | 0.60984023 |
| 71 | PAK3 | 0.60890353 |
| 72 | CSNK2A2 | 0.60346892 |
| 73 | MAPK12 | 0.60071381 |
| 74 | OXSR1 | 0.59617584 |
| 75 | AURKB | 0.59115124 |
| 76 | PIK3CA | 0.59013243 |
| 77 | PRKCA | 0.55790724 |
| 78 | CSNK1A1L | 0.55071175 |
| 79 | MAP3K8 | 0.54702511 |
| 80 | DYRK1A | 0.54462417 |
| 81 | CSNK1E | 0.54042375 |
| 82 | CDC7 | 0.53380734 |
| 83 | CSNK1G1 | 0.53271087 |
| 84 | MARK1 | 0.52993892 |
| 85 | VRK1 | 0.52802358 |
| 86 | PRKD3 | 0.52747011 |
| 87 | CSNK1A1 | 0.49748495 |
| 88 | DAPK1 | 0.49526574 |
| 89 | BTK | 0.49276544 |
| 90 | PRKCH | 0.48999394 |
| 91 | KIT | 0.47633420 |
| 92 | PASK | 0.46773512 |
| 93 | ITK | 0.44772649 |
| 94 | PRKACG | 0.44546604 |
| 95 | SYK | 0.44330490 |
| 96 | PRKCZ | 0.43845396 |
| 97 | ROCK2 | 0.43338040 |
| 98 | CSNK2A1 | 0.42435268 |
| 99 | ALK | 0.39741968 |
| 100 | ABL1 | 0.39532045 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 6.13957385 |
| 2 | Asthma_Homo sapiens_hsa05310 | 4.17029520 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.03319891 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.46641657 |
| 5 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 3.45307273 |
| 6 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.64905592 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.63289174 |
| 8 | Alzheimers disease_Homo sapiens_hsa05010 | 2.51645751 |
| 9 | Huntingtons disease_Homo sapiens_hsa05016 | 2.48925805 |
| 10 | Allograft rejection_Homo sapiens_hsa05330 | 2.43720837 |
| 11 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.33759583 |
| 12 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.25802110 |
| 13 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.19928896 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.07381193 |
| 15 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.79493227 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.77790456 |
| 17 | Sulfur relay system_Homo sapiens_hsa04122 | 1.27826784 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.26320384 |
| 19 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.23053154 |
| 20 | Phototransduction_Homo sapiens_hsa04744 | 1.21620777 |
| 21 | Nicotine addiction_Homo sapiens_hsa05033 | 1.17043302 |
| 22 | Protein export_Homo sapiens_hsa03060 | 1.14273524 |
| 23 | RNA polymerase_Homo sapiens_hsa03020 | 1.14272321 |
| 24 | Olfactory transduction_Homo sapiens_hsa04740 | 1.12843652 |
| 25 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.12289512 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.10522006 |
| 27 | Peroxisome_Homo sapiens_hsa04146 | 1.03162366 |
| 28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.02687324 |
| 29 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.01679674 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.01125252 |
| 31 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.97041907 |
| 32 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.96612897 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.93609264 |
| 34 | Morphine addiction_Homo sapiens_hsa05032 | 0.93429586 |
| 35 | Proteasome_Homo sapiens_hsa03050 | 0.91805612 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.90819575 |
| 37 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88362947 |
| 38 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.85079521 |
| 39 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.82895830 |
| 40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.80530170 |
| 41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.79083559 |
| 42 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79050132 |
| 43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.78166926 |
| 44 | Retinol metabolism_Homo sapiens_hsa00830 | 0.78042270 |
| 45 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.75395157 |
| 46 | GABAergic synapse_Homo sapiens_hsa04727 | 0.75084969 |
| 47 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71039149 |
| 48 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.68554426 |
| 49 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.68340957 |
| 50 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.67808827 |
| 51 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.67018112 |
| 52 | Basal transcription factors_Homo sapiens_hsa03022 | 0.65094402 |
| 53 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.65009574 |
| 54 | Circadian entrainment_Homo sapiens_hsa04713 | 0.64784360 |
| 55 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64353691 |
| 56 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.63801364 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.62141843 |
| 58 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.61292939 |
| 59 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.60450880 |
| 60 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.60063809 |
| 61 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.59450343 |
| 62 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58112357 |
| 63 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.56009752 |
| 64 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55942837 |
| 65 | Insulin secretion_Homo sapiens_hsa04911 | 0.54464055 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54145076 |
| 67 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.51105133 |
| 68 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.49227733 |
| 69 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.48807706 |
| 70 | Salivary secretion_Homo sapiens_hsa04970 | 0.47873616 |
| 71 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.47852875 |
| 72 | Metabolic pathways_Homo sapiens_hsa01100 | 0.47827213 |
| 73 | Purine metabolism_Homo sapiens_hsa00230 | 0.46252743 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.43697708 |
| 75 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42909600 |
| 76 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.42833471 |
| 77 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.42193497 |
| 78 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.42159818 |
| 79 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.40877419 |
| 80 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.38314162 |
| 81 | Taste transduction_Homo sapiens_hsa04742 | 0.38250497 |
| 82 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.38221624 |
| 83 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.38181465 |
| 84 | Leishmaniasis_Homo sapiens_hsa05140 | 0.37672335 |
| 85 | Base excision repair_Homo sapiens_hsa03410 | 0.36263018 |
| 86 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.35001869 |
| 87 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.32698122 |
| 88 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.32019312 |
| 89 | RNA degradation_Homo sapiens_hsa03018 | 0.28010913 |
| 90 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.27603617 |
| 91 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.27240381 |
| 92 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.26615370 |
| 93 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25115451 |
| 94 | Tuberculosis_Homo sapiens_hsa05152 | 0.25033215 |
| 95 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.24584631 |
| 96 | Alcoholism_Homo sapiens_hsa05034 | 0.23590065 |
| 97 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.23314204 |
| 98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.22702919 |
| 99 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.22519794 |
| 100 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.22313319 |

