RPL39P34

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1hypothalamus development (GO:0021854)9.91528214
2spinal cord association neuron differentiation (GO:0021527)8.88799601
3viral transcription (GO:0019083)7.35349986
4serotonin metabolic process (GO:0042428)7.26004751
5regulation of somitogenesis (GO:0014807)7.11561551
6translational termination (GO:0006415)6.90414187
7translational elongation (GO:0006414)6.17322974
8primary amino compound metabolic process (GO:1901160)6.16074163
9ribosomal small subunit biogenesis (GO:0042274)6.05733990
10ribosomal small subunit assembly (GO:0000028)6.02449045
11regulation of cellular respiration (GO:0043457)5.98395393
12pattern specification involved in kidney development (GO:0061004)5.83723980
13SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.78761469
14protein targeting to ER (GO:0045047)5.73478003
15cotranslational protein targeting to membrane (GO:0006613)5.72334332
16skeletal muscle organ development (GO:0060538)5.65924244
17purine nucleobase biosynthetic process (GO:0009113)5.63752890
18ribosomal large subunit biogenesis (GO:0042273)5.58818936
19viral life cycle (GO:0019058)5.50249018
20establishment of protein localization to endoplasmic reticulum (GO:0072599)5.48759718
21protein localization to endoplasmic reticulum (GO:0070972)5.41479816
22cellular protein complex disassembly (GO:0043624)5.32523274
23nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.91817340
24base-excision repair, AP site formation (GO:0006285)4.89972174
25sex differentiation (GO:0007548)4.77849034
26protein complex disassembly (GO:0043241)4.64089888
27pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.59981811
28translational initiation (GO:0006413)4.55370319
29photoreceptor cell differentiation (GO:0046530)4.48673355
30eye photoreceptor cell differentiation (GO:0001754)4.48673355
31auditory receptor cell differentiation (GO:0042491)4.42044117
32macromolecular complex disassembly (GO:0032984)4.40216383
33ribonucleoprotein complex biogenesis (GO:0022613)4.34408015
34RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)4.21872486
35tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)4.21872486
36regulation of oxidative phosphorylation (GO:0002082)4.08637803
37nucleobase biosynthetic process (GO:0046112)4.00278441
38regulation of transmission of nerve impulse (GO:0051969)3.96341431
39limb development (GO:0060173)3.90102020
40appendage development (GO:0048736)3.90102020
41regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)3.89274121
42neuron fate commitment (GO:0048663)3.88069774
43protein targeting to membrane (GO:0006612)3.82237359
44segment specification (GO:0007379)3.77556941
45pyrimidine nucleotide catabolic process (GO:0006244)3.72818357
46ncRNA 3-end processing (GO:0043628)3.71074372
47cardiovascular system development (GO:0072358)3.68995138
48chaperone-mediated protein transport (GO:0072321)3.68510508
49radial glial cell differentiation (GO:0060019)3.68391802
50phosphatidylserine acyl-chain remodeling (GO:0036150)3.61840316
51histone H2A acetylation (GO:0043968)3.60891498
52protein localization to cilium (GO:0061512)3.60175478
53head development (GO:0060322)3.59995414
54skeletal muscle tissue regeneration (GO:0043403)3.57398355
55spliceosomal complex assembly (GO:0000245)3.54416664
56body morphogenesis (GO:0010171)3.51654410
57cellular component biogenesis (GO:0044085)3.49479693
58indole-containing compound metabolic process (GO:0042430)3.47418908
59lens fiber cell development (GO:0070307)3.45111910
60nuclear-transcribed mRNA catabolic process (GO:0000956)3.43907262
61behavioral response to nicotine (GO:0035095)3.43719292
62maturation of SSU-rRNA (GO:0030490)3.41077110
63suckling behavior (GO:0001967)3.39773810
64phosphatidylinositol acyl-chain remodeling (GO:0036149)3.39383585
65norepinephrine metabolic process (GO:0042415)3.39094453
66mitochondrion transport along microtubule (GO:0047497)3.34966408
67establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.34966408
68ribosome biogenesis (GO:0042254)3.32379366
69pyrimidine nucleobase catabolic process (GO:0006208)3.30624546
70mRNA catabolic process (GO:0006402)3.29198773
71positive regulation of fatty acid biosynthetic process (GO:0045723)3.26551400
72establishment of mitochondrion localization (GO:0051654)3.26453903
73cell differentiation in spinal cord (GO:0021515)3.18706350
74peptidyl-threonine dephosphorylation (GO:0035970)3.15916760
75deoxyribonucleotide catabolic process (GO:0009264)3.12881529
76regulation of meiosis I (GO:0060631)3.12658947
77aggressive behavior (GO:0002118)3.09895696
78metanephric nephron tubule development (GO:0072234)3.09767807
79metanephric tubule development (GO:0072170)3.09767807
80deoxyribose phosphate catabolic process (GO:0046386)3.07798806
81lung epithelium development (GO:0060428)3.02683849
82adenine nucleotide transport (GO:0051503)3.00421354
83regulation of non-canonical Wnt signaling pathway (GO:2000050)3.00367499
84urate metabolic process (GO:0046415)2.95766602
85RNA catabolic process (GO:0006401)2.95327198
86translation (GO:0006412)2.94356009
87sulfate transmembrane transport (GO:1902358)2.93709849
88peroxisome fission (GO:0016559)2.92449427
89viral protein processing (GO:0019082)2.90228703
90positive regulation by host of viral transcription (GO:0043923)2.89338743
91negative regulation of response to food (GO:0032096)2.82378044
92negative regulation of appetite (GO:0032099)2.82378044
93mitochondrial calcium ion transport (GO:0006851)2.79280014
94coenzyme A biosynthetic process (GO:0015937)2.75495049
95pyrimidine deoxyribonucleotide metabolic process (GO:0009219)2.74536208
96nonmotile primary cilium assembly (GO:0035058)2.73715043
97viral entry into host cell (GO:0046718)2.71455974
98respiratory tube development (GO:0030323)2.71325644
99metanephric nephron epithelium development (GO:0072243)2.69684895
100exploration behavior (GO:0035640)2.68588741

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse5.89245918
2EZH2_22144423_ChIP-Seq_EOC_Human5.75625241
3HCFC1_20581084_ChIP-Seq_MESCs_Mouse4.86931823
4ELF1_17652178_ChIP-ChIP_JURKAT_Human3.59513713
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.18939662
6CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human3.03017159
7GABP_17652178_ChIP-ChIP_JURKAT_Human2.96546387
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.65154049
9EST1_17652178_ChIP-ChIP_JURKAT_Human2.63005199
10IGF1R_20145208_ChIP-Seq_DFB_Human2.40514159
11TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.37246462
12SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.33133492
13ERG_21242973_ChIP-ChIP_JURKAT_Human2.17026989
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.13606637
15SUZ12_27294783_Chip-Seq_ESCs_Mouse2.11930606
16GABP_19822575_ChIP-Seq_HepG2_Human1.94439736
17EZH2_27294783_Chip-Seq_ESCs_Mouse1.93946230
18CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.92060690
19HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.89705612
20RNF2_27304074_Chip-Seq_ESCs_Mouse1.89144797
21ESR1_15608294_ChIP-ChIP_MCF-7_Human1.86333939
22CBX2_27304074_Chip-Seq_ESCs_Mouse1.81834144
23VDR_21846776_ChIP-Seq_THP-1_Human1.80888432
24JARID2_20064375_ChIP-Seq_MESCs_Mouse1.80413452
25MYC_18555785_ChIP-Seq_MESCs_Mouse1.80097135
26TTF2_22483619_ChIP-Seq_HELA_Human1.76761630
27JARID2_20075857_ChIP-Seq_MESCs_Mouse1.65808815
28ELK1_22589737_ChIP-Seq_MCF10A_Human1.61308381
29JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.54959620
30REST_21632747_ChIP-Seq_MESCs_Mouse1.54889736
31NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.54629134
32GATA1_26923725_Chip-Seq_HPCs_Mouse1.52425486
33E2F1_17053090_ChIP-ChIP_MCF-7_Human1.51765017
34PCGF2_27294783_Chip-Seq_NPCs_Mouse1.51673592
35RBPJ_22232070_ChIP-Seq_NCS_Mouse1.51087060
36OCT4_19829295_ChIP-Seq_ESCs_Human1.48999256
37EZH2_27304074_Chip-Seq_ESCs_Mouse1.47041491
38EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.46921950
39CTCF_27219007_Chip-Seq_Bcells_Human1.43228091
40ERA_21632823_ChIP-Seq_H3396_Human1.43161415
41XRN2_22483619_ChIP-Seq_HELA_Human1.41121844
42MYC_18358816_ChIP-ChIP_MESCs_Mouse1.34055001
43MYC_19079543_ChIP-ChIP_MESCs_Mouse1.29274564
44CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.29091841
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.28948529
46THAP11_20581084_ChIP-Seq_MESCs_Mouse1.28002285
47PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.25837040
48SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.22720446
49RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.22026036
50KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.21537154
51SRY_22984422_ChIP-ChIP_TESTIS_Rat1.17222237
52EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.16729348
53SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.15970314
54FOXP1_21924763_ChIP-Seq_HESCs_Human1.15339878
55STAT1_20625510_ChIP-Seq_HELA_Human1.14812759
56REST_18959480_ChIP-ChIP_MESCs_Mouse1.13810279
57SMAD3_21741376_ChIP-Seq_ESCs_Human1.13755039
58NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse1.13652867
59EED_16625203_ChIP-ChIP_MESCs_Mouse1.10233281
60CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.09172348
61SOX2_16153702_ChIP-ChIP_HESCs_Human1.08610573
62LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08256579
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.08256348
64NFIB_24661679_ChIP-Seq_LUNG_Mouse1.08179941
65PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08030233
66CTCF_20526341_ChIP-Seq_ESCs_Human1.07953927
67BCAT_22108803_ChIP-Seq_LS180_Human1.07668492
68EZH2_18974828_ChIP-Seq_MESCs_Mouse1.06950178
69RNF2_18974828_ChIP-Seq_MESCs_Mouse1.06950178
70IRF1_19129219_ChIP-ChIP_H3396_Human1.05019112
71FOXP3_21729870_ChIP-Seq_TREG_Human1.04993844
72PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.04804981
73SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.03048873
74IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02702694
75GBX2_23144817_ChIP-Seq_PC3_Human1.02059246
76ZNF274_21170338_ChIP-Seq_K562_Hela0.98633533
77SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.97969799
78DNAJC2_21179169_ChIP-ChIP_NT2_Human0.96715736
79BCL6_27268052_Chip-Seq_Bcells_Human0.96199469
80POU5F1_16153702_ChIP-ChIP_HESCs_Human0.96063950
81TP53_16413492_ChIP-PET_HCT116_Human0.95742867
82SUZ12_16625203_ChIP-ChIP_MESCs_Mouse0.94760231
83AHR_22903824_ChIP-Seq_MCF-7_Human0.93077283
84ETV2_25802403_ChIP-Seq_MESCs_Mouse0.92096624
85MTF2_20144788_ChIP-Seq_MESCs_Mouse0.91307826
86GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91020128
87BCOR_27268052_Chip-Seq_Bcells_Human0.90551444
88RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.88080653
89SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.87811548
90YY1_22570637_ChIP-Seq_MALME-3M_Human0.86768397
91SOX11_22085726_ChIP-Seq_ESNs_Mouse0.86056261
92DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85659147
93PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.85543411
94CTBP1_25329375_ChIP-Seq_LNCAP_Human0.84412806
95CTCF_18555785_ChIP-Seq_MESCs_Mouse0.83851840
96CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.83792624
97BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.83659969
98TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.82754849
99MYC_19030024_ChIP-ChIP_MESCs_Mouse0.81734036
100SMC4_20622854_ChIP-Seq_HELA_Human0.81284776

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005645_abnormal_hypothalamus_physiol6.78073648
2MP0003011_delayed_dark_adaptation5.83515154
3MP0002822_catalepsy5.48056717
4MP0005646_abnormal_pituitary_gland4.74870416
5MP0002638_abnormal_pupillary_reflex4.07853957
6MP0002163_abnormal_gland_morphology3.75485800
7MP0009379_abnormal_foot_pigmentation3.50793435
8MP0005379_endocrine/exocrine_gland_phen2.68571220
9MP0003693_abnormal_embryo_hatching2.54950583
10MP0005451_abnormal_body_composition2.35047035
11MP0005670_abnormal_white_adipose2.11869893
12MP0002653_abnormal_ependyma_morphology2.05562167
13MP0000631_abnormal_neuroendocrine_gland1.95342741
14MP0002837_dystrophic_cardiac_calcinosis1.82621072
15MP0003787_abnormal_imprinting1.73392945
16MP0006292_abnormal_olfactory_placode1.72362399
17MP0003123_paternal_imprinting1.70054228
18MP0005647_abnormal_sex_gland1.67217654
19MP0002735_abnormal_chemical_nociception1.66784234
20MP0001293_anophthalmia1.61317722
21MP0008877_abnormal_DNA_methylation1.59935882
22MP0008789_abnormal_olfactory_epithelium1.57202434
23MP0003950_abnormal_plasma_membrane1.47277119
24MP0001905_abnormal_dopamine_level1.41313714
25MP0002733_abnormal_thermal_nociception1.40046337
26MP0003136_yellow_coat_color1.39827465
27MP0005499_abnormal_olfactory_system1.37344466
28MP0005394_taste/olfaction_phenotype1.37344466
29MP0002938_white_spotting1.31685369
30MP0008569_lethality_at_weaning1.30615153
31MP0002572_abnormal_emotion/affect_behav1.30127309
32MP0000750_abnormal_muscle_regeneration1.28409757
33MP0003186_abnormal_redox_activity1.28322418
34MP0004130_abnormal_muscle_cell1.25335576
35MP0005075_abnormal_melanosome_morpholog1.17466209
36MP0002138_abnormal_hepatobiliary_system1.16445557
37MP0003122_maternal_imprinting1.15205076
38MP0005171_absent_coat_pigmentation1.10956278
39MP0001970_abnormal_pain_threshold1.08315420
40MP0001529_abnormal_vocalization1.07606461
41MP0009278_abnormal_bone_marrow1.06823649
42MP0002063_abnormal_learning/memory/cond1.03792246
43MP0002736_abnormal_nociception_after1.02488681
44MP0000778_abnormal_nervous_system1.02461299
45MP0003635_abnormal_synaptic_transmissio1.01700963
46MP0002095_abnormal_skin_pigmentation1.00261199
47MP0009053_abnormal_anal_canal0.99037982
48MP0001968_abnormal_touch/_nociception0.98698508
49MP0004142_abnormal_muscle_tone0.97110721
50MP0000049_abnormal_middle_ear0.97041908
51MP0001440_abnormal_grooming_behavior0.95602243
52MP0002067_abnormal_sensory_capabilities0.95522075
53MP0005195_abnormal_posterior_eye0.94205276
54MP0002064_seizures0.92522631
55MP0005551_abnormal_eye_electrophysiolog0.91745902
56MP0001764_abnormal_homeostasis0.88993783
57MP0005084_abnormal_gallbladder_morpholo0.88991271
58MP0009745_abnormal_behavioral_response0.88976425
59MP0002102_abnormal_ear_morphology0.88424070
60MP0002557_abnormal_social/conspecific_i0.88385604
61MP0000372_irregular_coat_pigmentation0.88100014
62MP0008875_abnormal_xenobiotic_pharmacok0.85949348
63MP0005248_abnormal_Harderian_gland0.84882160
64MP0000163_abnormal_cartilage_morphology0.84284822
65MP0001340_abnormal_eyelid_morphology0.83772959
66MP0008961_abnormal_basal_metabolism0.82249210
67MP0003115_abnormal_respiratory_system0.82169554
68MP0009046_muscle_twitch0.79228115
69MP0004858_abnormal_nervous_system0.78940474
70MP0002069_abnormal_eating/drinking_beha0.78746488
71MP0005360_urolithiasis0.78274986
72MP0005409_darkened_coat_color0.77973094
73MP0002233_abnormal_nose_morphology0.76528258
74MP0002075_abnormal_coat/hair_pigmentati0.75549452
75MP0002876_abnormal_thyroid_physiology0.73313799
76MP0001324_abnormal_eye_pigmentation0.73079831
77MP0002249_abnormal_larynx_morphology0.72944098
78MP0005253_abnormal_eye_physiology0.71647729
79MP0005391_vision/eye_phenotype0.70844266
80MP0001486_abnormal_startle_reflex0.70276207
81MP0002932_abnormal_joint_morphology0.68125276
82MP0001348_abnormal_lacrimal_gland0.67814240
83MP0003959_abnormal_lean_body0.66529813
84MP0001186_pigmentation_phenotype0.66464130
85MP0000678_abnormal_parathyroid_gland0.66184508
86MP0002272_abnormal_nervous_system0.64985305
87MP0000955_abnormal_spinal_cord0.62007404
88MP0005377_hearing/vestibular/ear_phenot0.61921369
89MP0003878_abnormal_ear_physiology0.61921369
90MP0003183_abnormal_peptide_metabolism0.61203112
91MP0004147_increased_porphyrin_level0.60860200
92MP0004859_abnormal_synaptic_plasticity0.58554923
93MP0000566_synostosis0.58210706
94MP0001986_abnormal_taste_sensitivity0.56513506
95MP0000653_abnormal_sex_gland0.56510997
96MP0001286_abnormal_eye_development0.56395022
97MP0002752_abnormal_somatic_nervous0.55916288
98MP0004924_abnormal_behavior0.55252641
99MP0005386_behavior/neurological_phenoty0.55252641
100MP0002111_abnormal_tail_morphology0.55201827

Predicted human phenotypes

RankGene SetZ-score
1Gout (HP:0001997)6.10281945
2Aplasia/Hypoplasia of the sacrum (HP:0008517)5.99252162
3Action tremor (HP:0002345)4.32663927
4Oligodactyly (hands) (HP:0001180)4.28484789
5Anophthalmia (HP:0000528)4.26982601
6Oligodactyly (HP:0012165)4.10906243
7Maternal diabetes (HP:0009800)4.07601329
8Pancreatic fibrosis (HP:0100732)3.96681914
9Vacuolated lymphocytes (HP:0001922)3.92344658
10Septo-optic dysplasia (HP:0100842)3.87261377
11Elfin facies (HP:0004428)3.74612838
12Acute necrotizing encephalopathy (HP:0006965)3.74434890
13Renal duplication (HP:0000075)3.53381783
14Reticulocytopenia (HP:0001896)3.52616368
15Overriding aorta (HP:0002623)3.38637975
16Hyperthyroidism (HP:0000836)3.30823183
17Abnormality of the diencephalon (HP:0010662)3.29809590
18Rib fusion (HP:0000902)3.22231859
19Abnormal mitochondria in muscle tissue (HP:0008316)3.21331967
20Increased purine levels (HP:0004368)3.14772748
21Hyperuricemia (HP:0002149)3.14772748
22Renovascular hypertension (HP:0100817)3.14559585
23Segmental peripheral demyelination/remyelination (HP:0003481)3.12443087
24Hyperacusis (HP:0010780)3.06392984
25Acute encephalopathy (HP:0006846)3.04769680
26Rhabdomyosarcoma (HP:0002859)3.03528189
27Conjugated hyperbilirubinemia (HP:0002908)2.99710797
28J-shaped sella turcica (HP:0002680)2.93697879
29Hypoplastic pelvis (HP:0008839)2.92788964
30Progressive macrocephaly (HP:0004481)2.90599247
31Flat cornea (HP:0007720)2.88649950
32Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.86585471
33Degeneration of the lateral corticospinal tracts (HP:0002314)2.86585471
34Volvulus (HP:0002580)2.83885536
35Akinesia (HP:0002304)2.73316746
36Synostosis of carpal bones (HP:0005048)2.68575475
37Insomnia (HP:0100785)2.64269721
38Optic nerve hypoplasia (HP:0000609)2.61151567
39Fair hair (HP:0002286)2.47321384
40Abnormal number of incisors (HP:0011064)2.39881284
41Menstrual irregularities (HP:0000858)2.36917729
42Arterial tortuosity (HP:0005116)2.34667761
43Abnormality of purine metabolism (HP:0004352)2.34353056
44Mitochondrial inheritance (HP:0001427)2.33033092
45Anencephaly (HP:0002323)2.31388850
46Obsessive-compulsive behavior (HP:0000722)2.31243992
47Curly hair (HP:0002212)2.30578155
48Nephronophthisis (HP:0000090)2.29377715
49Abnormality of the carotid arteries (HP:0005344)2.25025049
50Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.24267552
51Severe visual impairment (HP:0001141)2.24049081
52Areflexia of lower limbs (HP:0002522)2.20331982
53Short femoral neck (HP:0100864)2.19142511
54Gonadotropin excess (HP:0000837)2.18520513
55Hepatoblastoma (HP:0002884)2.17783403
56Radioulnar synostosis (HP:0002974)2.17544308
57Vascular tortuosity (HP:0004948)2.14087071
58Myelomeningocele (HP:0002475)2.13386767
59Hypobetalipoproteinemia (HP:0003563)2.10116465
60Increased nuchal translucency (HP:0010880)2.08851282
61Abnormality of the 4th metacarpal (HP:0010012)2.06883522
62Postaxial foot polydactyly (HP:0001830)2.06554048
63Inability to walk (HP:0002540)2.05551965
64Annular pancreas (HP:0001734)2.04927452
65Pointed chin (HP:0000307)2.01341328
66Pulmonary artery stenosis (HP:0004415)2.00542534
67Acanthocytosis (HP:0001927)1.97579185
68Abnormality of the corticospinal tract (HP:0002492)1.97184988
69Keratoconus (HP:0000563)1.96003202
70Increased corneal curvature (HP:0100692)1.96003202
71Exotropia (HP:0000577)1.90707948
72Enlarged penis (HP:0000040)1.90255115
73Abnormality of cells of the erythroid lineage (HP:0012130)1.89499493
74Nephrolithiasis (HP:0000787)1.89124409
75Medial flaring of the eyebrow (HP:0010747)1.89073201
76True hermaphroditism (HP:0010459)1.88188192
77Decreased muscle mass (HP:0003199)1.87371792
78Intestinal atresia (HP:0011100)1.84657660
79Leukodystrophy (HP:0002415)1.83482411
80Growth hormone deficiency (HP:0000824)1.83126233
81Generalized hypopigmentation of hair (HP:0011358)1.82545511
82Pendular nystagmus (HP:0012043)1.80661945
83Drooling (HP:0002307)1.80435124
84Patent foramen ovale (HP:0001655)1.79255661
85Xanthomatosis (HP:0000991)1.79248179
86Tetraplegia (HP:0002445)1.78562274
87Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.78553229
88Abnormality of DNA repair (HP:0003254)1.78258164
89Macrocytic anemia (HP:0001972)1.75292565
90Absent septum pellucidum (HP:0001331)1.74515688
91Agitation (HP:0000713)1.71074898
92Left ventricular hypertrophy (HP:0001712)1.68885457
93Abnormality of the aortic arch (HP:0012303)1.68751528
94Epidermoid cyst (HP:0200040)1.68547838
95Cerebral edema (HP:0002181)1.68433960
96Gait imbalance (HP:0002141)1.67252514
97Polyphagia (HP:0002591)1.66673998
98Prostate neoplasm (HP:0100787)1.66186454
99Excessive salivation (HP:0003781)1.65166551
100Neoplasm of striated muscle (HP:0009728)1.64100499

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K26.71632222
2CDK195.17335685
3LIMK13.98348704
4PRKD33.19303569
5CAMK1D3.12999514
6DYRK22.75294984
7CAMKK22.70015977
8WNK12.56580630
9CAMK1G2.52534198
10LRRK22.48920002
11BMPR1B2.44903582
12TYRO32.08736402
13DYRK31.96261076
14MARK11.85225460
15PAK61.80116665
16RAF11.80028132
17NTRK21.74871059
18DMPK1.52104113
19VRK21.51961891
20MAP4K11.51359574
21PNCK1.45111860
22DYRK1B1.34935844
23CLK11.34100873
24MAP3K111.28474569
25PAK31.27690910
26KSR21.14312935
27NUAK11.13684504
28MAP2K71.12669682
29MAP3K41.10135556
30TIE11.01940375
31WNK41.01551622
32NME11.00209309
33ZAK0.99941844
34CDK70.99143296
35PRKCG0.95602411
36MAP3K100.92100151
37EPHA40.83519976
38CDC42BPA0.82888047
39CAMK10.82816173
40CDK11A0.78057881
41MAP3K70.71381532
42BCR0.69816140
43CSNK1G20.69235326
44PHKG20.68492619
45PHKG10.68492619
46PRKD20.67825788
47ROCK10.67481430
48FES0.66879632
49MAPK130.66508102
50CDK140.66243434
51MAP2K40.65433558
52MAP3K130.64290992
53CSNK1G10.64252132
54CSNK1G30.61280544
55MARK20.59509557
56CAMKK10.58462665
57DAPK30.57836856
58CAMK40.57154939
59EPHB20.55728295
60PRKCQ0.55393111
61MAPK70.53679198
62ROCK20.51974644
63PAK10.49512730
64KSR10.48763574
65STK390.47869280
66STK160.47579806
67CSNK2A20.47246787
68TESK10.46955010
69GRK10.46512990
70RPS6KA10.45563616
71PKN10.44638049
72RPS6KB10.44634374
73CSNK1A1L0.42374401
74EIF2AK20.40390954
75PRKCI0.39560251
76SIK10.37549252
77CSNK2A10.37076437
78PRKCZ0.36555096
79DYRK1A0.36531019
80OXSR10.36508169
81PRKCH0.35496454
82PIM20.34824849
83PRKDC0.34810074
84MAP2K10.34418933
85STK380.33678519
86ABL20.33665132
87STK100.33002406
88EPHA30.32903510
89ADRBK10.32695036
90BTK0.32541899
91SGK10.31263092
92CDK90.30523096
93WNK30.30018270
94PRKACA0.26290918
95CAMK2B0.25879536
96RPS6KA60.25645553
97ARAF0.24808690
98AURKA0.23864044
99PRKCE0.23512233
100PRKACB0.23345067

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030106.29491959
2Butanoate metabolism_Homo sapiens_hsa006503.03988368
3Steroid biosynthesis_Homo sapiens_hsa001002.74078277
4Sulfur relay system_Homo sapiens_hsa041222.50771383
5RNA polymerase_Homo sapiens_hsa030202.28020987
6Mismatch repair_Homo sapiens_hsa034302.22255799
7alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.19069197
8Linoleic acid metabolism_Homo sapiens_hsa005912.16135467
9DNA replication_Homo sapiens_hsa030302.15091373
10Nucleotide excision repair_Homo sapiens_hsa034202.07037106
11Base excision repair_Homo sapiens_hsa034101.98435851
12Parkinsons disease_Homo sapiens_hsa050121.86686085
13Fatty acid degradation_Homo sapiens_hsa000711.83902141
14Fatty acid metabolism_Homo sapiens_hsa012121.81397708
15Oxidative phosphorylation_Homo sapiens_hsa001901.78899387
16Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.73439278
17Homologous recombination_Homo sapiens_hsa034401.62629087
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.61636686
19Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.59074036
20Primary bile acid biosynthesis_Homo sapiens_hsa001201.58890846
21Ether lipid metabolism_Homo sapiens_hsa005651.54114500
22Huntingtons disease_Homo sapiens_hsa050161.51643631
23Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.49614776
24Cardiac muscle contraction_Homo sapiens_hsa042601.49555014
25Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.48537185
26Pyrimidine metabolism_Homo sapiens_hsa002401.46493938
27RNA degradation_Homo sapiens_hsa030181.46040214
28Basal cell carcinoma_Homo sapiens_hsa052171.45704664
29Notch signaling pathway_Homo sapiens_hsa043301.44568037
30Purine metabolism_Homo sapiens_hsa002301.43508459
31Pentose phosphate pathway_Homo sapiens_hsa000301.43187041
32Fat digestion and absorption_Homo sapiens_hsa049751.39651501
33RNA transport_Homo sapiens_hsa030131.29882971
34Hedgehog signaling pathway_Homo sapiens_hsa043401.26941240
35Morphine addiction_Homo sapiens_hsa050321.26031457
36Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.24836650
37Alzheimers disease_Homo sapiens_hsa050101.13899223
38Folate biosynthesis_Homo sapiens_hsa007901.13044878
39Fatty acid biosynthesis_Homo sapiens_hsa000611.10314492
40Arachidonic acid metabolism_Homo sapiens_hsa005901.09379790
41Propanoate metabolism_Homo sapiens_hsa006401.07592464
42Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.04040700
43Retinol metabolism_Homo sapiens_hsa008301.04007849
44Hippo signaling pathway_Homo sapiens_hsa043901.02906249
45Nicotine addiction_Homo sapiens_hsa050330.99950842
46Peroxisome_Homo sapiens_hsa041460.98565977
47Olfactory transduction_Homo sapiens_hsa047400.97938590
48Biosynthesis of amino acids_Homo sapiens_hsa012300.97920725
49Spliceosome_Homo sapiens_hsa030400.96090254
50Wnt signaling pathway_Homo sapiens_hsa043100.90499372
51Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.87309129
52beta-Alanine metabolism_Homo sapiens_hsa004100.87018520
53Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.85532482
54Glycerophospholipid metabolism_Homo sapiens_hsa005640.85072455
55Carbon metabolism_Homo sapiens_hsa012000.83635171
56Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.78899730
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77040339
58Axon guidance_Homo sapiens_hsa043600.74492698
59Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.73905006
60Choline metabolism in cancer_Homo sapiens_hsa052310.73590274
61Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.73162434
62Glycerolipid metabolism_Homo sapiens_hsa005610.72943569
63Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.70684121
64Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.70143170
65Dorso-ventral axis formation_Homo sapiens_hsa043200.68302322
66Vitamin B6 metabolism_Homo sapiens_hsa007500.66627668
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66251503
68Long-term depression_Homo sapiens_hsa047300.63963263
69Serotonergic synapse_Homo sapiens_hsa047260.62001108
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.58141651
71Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.57572546
72Taste transduction_Homo sapiens_hsa047420.57343852
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.57201409
74Chemical carcinogenesis_Homo sapiens_hsa052040.56782871
75Starch and sucrose metabolism_Homo sapiens_hsa005000.54687870
76Metabolic pathways_Homo sapiens_hsa011000.53390663
77Salivary secretion_Homo sapiens_hsa049700.51455207
78Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.46842209
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.46639833
80GABAergic synapse_Homo sapiens_hsa047270.45062979
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.44720146
82Protein export_Homo sapiens_hsa030600.43407018
83Phototransduction_Homo sapiens_hsa047440.39475826
84Circadian entrainment_Homo sapiens_hsa047130.38822557
85Melanogenesis_Homo sapiens_hsa049160.38042019
86Fatty acid elongation_Homo sapiens_hsa000620.37320268
87Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.37295520
88Melanoma_Homo sapiens_hsa052180.33030353
89Ras signaling pathway_Homo sapiens_hsa040140.32934818
90Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.32775218
91Ovarian steroidogenesis_Homo sapiens_hsa049130.32618820
92Colorectal cancer_Homo sapiens_hsa052100.31875255
93Pyruvate metabolism_Homo sapiens_hsa006200.31825678
94Steroid hormone biosynthesis_Homo sapiens_hsa001400.30404463
95Cocaine addiction_Homo sapiens_hsa050300.29855089
96Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.29819772
97Fanconi anemia pathway_Homo sapiens_hsa034600.25081706
98Glutathione metabolism_Homo sapiens_hsa004800.23220866
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.22122816
100Gap junction_Homo sapiens_hsa045400.21557342

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