

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.31815406 |
| 2 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 5.03795752 |
| 3 | DNA deamination (GO:0045006) | 4.97287133 |
| 4 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.81751850 |
| 5 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.64453017 |
| 6 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 4.49723732 |
| 7 | viral transcription (GO:0019083) | 4.45297230 |
| 8 | translational termination (GO:0006415) | 4.33835096 |
| 9 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.20593003 |
| 10 | cotranslational protein targeting to membrane (GO:0006613) | 4.18867670 |
| 11 | protein targeting to ER (GO:0045047) | 4.12907258 |
| 12 | fucose catabolic process (GO:0019317) | 4.11607924 |
| 13 | L-fucose metabolic process (GO:0042354) | 4.11607924 |
| 14 | L-fucose catabolic process (GO:0042355) | 4.11607924 |
| 15 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.11379416 |
| 16 | ATP synthesis coupled proton transport (GO:0015986) | 4.11379416 |
| 17 | GTP biosynthetic process (GO:0006183) | 4.09320801 |
| 18 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.98846016 |
| 19 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.98740892 |
| 20 | chaperone-mediated protein transport (GO:0072321) | 3.98710511 |
| 21 | ribosomal large subunit biogenesis (GO:0042273) | 3.92802615 |
| 22 | protein localization to endoplasmic reticulum (GO:0070972) | 3.88574366 |
| 23 | translational elongation (GO:0006414) | 3.80798888 |
| 24 | behavioral response to nicotine (GO:0035095) | 3.75310912 |
| 25 | regulation of immunoglobulin secretion (GO:0051023) | 3.74050631 |
| 26 | protein complex biogenesis (GO:0070271) | 3.71060821 |
| 27 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.70386124 |
| 28 | rRNA modification (GO:0000154) | 3.67710913 |
| 29 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.61269398 |
| 30 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.61269398 |
| 31 | UTP biosynthetic process (GO:0006228) | 3.58996490 |
| 32 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.58542373 |
| 33 | ribosomal small subunit biogenesis (GO:0042274) | 3.53954775 |
| 34 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.52170775 |
| 35 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.52170775 |
| 36 | NADH dehydrogenase complex assembly (GO:0010257) | 3.52170775 |
| 37 | response to xenobiotic stimulus (GO:0009410) | 3.44857938 |
| 38 | rRNA methylation (GO:0031167) | 3.43209749 |
| 39 | CTP metabolic process (GO:0046036) | 3.39894704 |
| 40 | CTP biosynthetic process (GO:0006241) | 3.39894704 |
| 41 | proteasome assembly (GO:0043248) | 3.39331060 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.36317973 |
| 43 | UTP metabolic process (GO:0046051) | 3.28469336 |
| 44 | viral life cycle (GO:0019058) | 3.27283980 |
| 45 | translational initiation (GO:0006413) | 3.25548972 |
| 46 | translation (GO:0006412) | 3.25394626 |
| 47 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.22078041 |
| 48 | protein neddylation (GO:0045116) | 3.22050171 |
| 49 | cellular protein complex disassembly (GO:0043624) | 3.20105510 |
| 50 | regulation of chronic inflammatory response (GO:0002676) | 3.19230986 |
| 51 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.16475821 |
| 52 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.12990344 |
| 53 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.07406373 |
| 54 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.03003666 |
| 55 | cellular component biogenesis (GO:0044085) | 3.02194908 |
| 56 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.01946448 |
| 57 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.98301939 |
| 58 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.98121888 |
| 59 | response to pheromone (GO:0019236) | 2.97798839 |
| 60 | maturation of SSU-rRNA (GO:0030490) | 2.96709565 |
| 61 | regulation of regulatory T cell differentiation (GO:0045589) | 2.95027872 |
| 62 | pseudouridine synthesis (GO:0001522) | 2.94474229 |
| 63 | ubiquinone biosynthetic process (GO:0006744) | 2.94325757 |
| 64 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.94206730 |
| 65 | cellular response to exogenous dsRNA (GO:0071360) | 2.92780653 |
| 66 | signal peptide processing (GO:0006465) | 2.91734882 |
| 67 | base-excision repair, AP site formation (GO:0006285) | 2.89742178 |
| 68 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 2.87627951 |
| 69 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.86532517 |
| 70 | epithelial cilium movement (GO:0003351) | 2.86259279 |
| 71 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.85243740 |
| 72 | protein-cofactor linkage (GO:0018065) | 2.84755201 |
| 73 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.83802918 |
| 74 | tRNA processing (GO:0008033) | 2.82688498 |
| 75 | positive regulation of defense response to virus by host (GO:0002230) | 2.81928018 |
| 76 | rRNA processing (GO:0006364) | 2.79384706 |
| 77 | inositol phosphate dephosphorylation (GO:0046855) | 2.78885049 |
| 78 | phosphorylated carbohydrate dephosphorylation (GO:0046838) | 2.78885049 |
| 79 | parturition (GO:0007567) | 2.78875717 |
| 80 | protein polyglutamylation (GO:0018095) | 2.78841916 |
| 81 | cytidine deamination (GO:0009972) | 2.77722660 |
| 82 | cytidine metabolic process (GO:0046087) | 2.77722660 |
| 83 | cytidine catabolic process (GO:0006216) | 2.77722660 |
| 84 | rRNA metabolic process (GO:0016072) | 2.76369847 |
| 85 | regulation of podosome assembly (GO:0071801) | 2.76031166 |
| 86 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.73444228 |
| 87 | axoneme assembly (GO:0035082) | 2.72963695 |
| 88 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.72535250 |
| 89 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.70975218 |
| 90 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.65779502 |
| 91 | protein targeting to membrane (GO:0006612) | 2.64652957 |
| 92 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.62200362 |
| 93 | ubiquinone metabolic process (GO:0006743) | 2.62068208 |
| 94 | protein complex disassembly (GO:0043241) | 2.60913465 |
| 95 | inositol phosphate catabolic process (GO:0071545) | 2.60598108 |
| 96 | electron transport chain (GO:0022900) | 2.58677912 |
| 97 | negative regulation of acute inflammatory response (GO:0002674) | 2.57823394 |
| 98 | respiratory electron transport chain (GO:0022904) | 2.57755840 |
| 99 | maturation of 5.8S rRNA (GO:0000460) | 2.57204195 |
| 100 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.56826326 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.24852255 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.69117693 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.57521737 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.21167176 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.86093715 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.82328712 |
| 7 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.78286629 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.56170042 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.53448757 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.48103368 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.45722420 |
| 12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.37655047 |
| 13 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.19554495 |
| 14 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.18821413 |
| 15 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.18573158 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.11106589 |
| 17 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.10252368 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.01842264 |
| 19 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.93820950 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.93626438 |
| 21 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.91205490 |
| 22 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.89578921 |
| 23 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.84873139 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.82661633 |
| 25 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.79390527 |
| 26 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.75348044 |
| 27 | EWS_26573619_Chip-Seq_HEK293_Human | 1.74140252 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.71734581 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.66892551 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.65128614 |
| 31 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.64712082 |
| 32 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.62144635 |
| 33 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.59311509 |
| 34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.54743662 |
| 35 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.53473676 |
| 36 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.47637820 |
| 37 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.47247535 |
| 38 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.40940899 |
| 39 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.40422675 |
| 40 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.40092122 |
| 41 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.36737268 |
| 42 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.35759309 |
| 43 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.35759309 |
| 44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34965051 |
| 45 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34649455 |
| 46 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.33583384 |
| 47 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.30930978 |
| 48 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.30257995 |
| 49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.28272291 |
| 50 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.25863828 |
| 51 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.22543985 |
| 52 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20699290 |
| 53 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.19962000 |
| 54 | AR_20517297_ChIP-Seq_VCAP_Human | 1.19887605 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19367331 |
| 56 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19367331 |
| 57 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.17828875 |
| 58 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.16368171 |
| 59 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16321763 |
| 60 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.16291566 |
| 61 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.13280870 |
| 62 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.11133956 |
| 63 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.10469000 |
| 64 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.09510665 |
| 65 | ERA_21632823_ChIP-Seq_H3396_Human | 1.08440454 |
| 66 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.07766829 |
| 67 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.06389812 |
| 68 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.05746255 |
| 69 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.04026034 |
| 70 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.03443902 |
| 71 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.03139689 |
| 72 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.02228107 |
| 73 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.01667574 |
| 74 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.00533876 |
| 75 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.99596944 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.99596944 |
| 77 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.99190076 |
| 78 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.99053252 |
| 79 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.98108769 |
| 80 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.97479725 |
| 81 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.96947286 |
| 82 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.96267679 |
| 83 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.96011884 |
| 84 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.95065526 |
| 85 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.93677271 |
| 86 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.92933041 |
| 87 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.92550918 |
| 88 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.89286956 |
| 89 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.89138410 |
| 90 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.89122457 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.89079435 |
| 92 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.88239122 |
| 93 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.88157397 |
| 94 | GATA3_26560356_Chip-Seq_TH2_Human | 0.86984947 |
| 95 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.86125448 |
| 96 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.86011741 |
| 97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.85466662 |
| 98 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.84494030 |
| 99 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.84417971 |
| 100 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.84274958 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0004147_increased_porphyrin_level | 2.90995477 |
| 2 | MP0008877_abnormal_DNA_methylation | 2.80700403 |
| 3 | MP0005646_abnormal_pituitary_gland | 2.74804734 |
| 4 | MP0008875_abnormal_xenobiotic_pharmacok | 2.63717971 |
| 5 | MP0001873_stomach_inflammation | 2.56324044 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.46451023 |
| 7 | MP0001835_abnormal_antigen_presentation | 2.30340438 |
| 8 | MP0002163_abnormal_gland_morphology | 2.20113860 |
| 9 | MP0003186_abnormal_redox_activity | 2.19522964 |
| 10 | MP0003787_abnormal_imprinting | 2.16851915 |
| 11 | MP0002876_abnormal_thyroid_physiology | 2.08087571 |
| 12 | MP0008872_abnormal_physiological_respon | 2.06816052 |
| 13 | MP0005671_abnormal_response_to | 2.06200113 |
| 14 | MP0005645_abnormal_hypothalamus_physiol | 2.05713514 |
| 15 | MP0004885_abnormal_endolymph | 1.98399736 |
| 16 | MP0002653_abnormal_ependyma_morphology | 1.97538379 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.92002246 |
| 18 | MP0004142_abnormal_muscle_tone | 1.88583351 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 1.83029461 |
| 20 | MP0003122_maternal_imprinting | 1.79826536 |
| 21 | MP0001986_abnormal_taste_sensitivity | 1.70465179 |
| 22 | MP0003195_calcinosis | 1.70346692 |
| 23 | MP0002837_dystrophic_cardiac_calcinosis | 1.70194222 |
| 24 | MP0005379_endocrine/exocrine_gland_phen | 1.66533354 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 1.59633047 |
| 26 | MP0004782_abnormal_surfactant_physiolog | 1.57218864 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.55611495 |
| 28 | MP0001968_abnormal_touch/_nociception | 1.54139336 |
| 29 | MP0009379_abnormal_foot_pigmentation | 1.52588915 |
| 30 | MP0002736_abnormal_nociception_after | 1.51483030 |
| 31 | MP0002272_abnormal_nervous_system | 1.50796458 |
| 32 | MP0001501_abnormal_sleep_pattern | 1.45614949 |
| 33 | MP0005389_reproductive_system_phenotype | 1.43314862 |
| 34 | MP0003718_maternal_effect | 1.42836408 |
| 35 | MP0002938_white_spotting | 1.41707874 |
| 36 | MP0001348_abnormal_lacrimal_gland | 1.41282587 |
| 37 | MP0003121_genomic_imprinting | 1.38454173 |
| 38 | MP0001790_abnormal_immune_system | 1.37121879 |
| 39 | MP0005387_immune_system_phenotype | 1.37121879 |
| 40 | MP0005084_abnormal_gallbladder_morpholo | 1.30191405 |
| 41 | MP0002102_abnormal_ear_morphology | 1.28501054 |
| 42 | MP0000685_abnormal_immune_system | 1.28430826 |
| 43 | MP0003011_delayed_dark_adaptation | 1.26644028 |
| 44 | MP0001293_anophthalmia | 1.25621401 |
| 45 | MP0004145_abnormal_muscle_electrophysio | 1.25105299 |
| 46 | MP0000372_irregular_coat_pigmentation | 1.24773539 |
| 47 | MP0001919_abnormal_reproductive_system | 1.24572855 |
| 48 | MP0002254_reproductive_system_inflammat | 1.20219430 |
| 49 | MP0006276_abnormal_autonomic_nervous | 1.20179658 |
| 50 | MP0001800_abnormal_humoral_immune | 1.18713985 |
| 51 | MP0003878_abnormal_ear_physiology | 1.16500165 |
| 52 | MP0005377_hearing/vestibular/ear_phenot | 1.16500165 |
| 53 | MP0001905_abnormal_dopamine_level | 1.14639050 |
| 54 | MP0005410_abnormal_fertilization | 1.14462957 |
| 55 | MP0001440_abnormal_grooming_behavior | 1.14288896 |
| 56 | MP0000631_abnormal_neuroendocrine_gland | 1.13589700 |
| 57 | MP0005253_abnormal_eye_physiology | 1.13176755 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.12219217 |
| 59 | MP0002277_abnormal_respiratory_mucosa | 1.11128926 |
| 60 | MP0002095_abnormal_skin_pigmentation | 1.10986771 |
| 61 | MP0005075_abnormal_melanosome_morpholog | 1.10694543 |
| 62 | MP0002160_abnormal_reproductive_system | 1.10656124 |
| 63 | MP0009785_altered_susceptibility_to | 1.09342503 |
| 64 | MP0009745_abnormal_behavioral_response | 1.09295208 |
| 65 | MP0003436_decreased_susceptibility_to | 1.09067910 |
| 66 | MP0008775_abnormal_heart_ventricle | 1.08897339 |
| 67 | MP0002638_abnormal_pupillary_reflex | 1.08896018 |
| 68 | MP0001502_abnormal_circadian_rhythm | 1.06582236 |
| 69 | MP0001663_abnormal_digestive_system | 1.05316764 |
| 70 | MP0001984_abnormal_olfaction | 1.04051457 |
| 71 | MP0005167_abnormal_blood-brain_barrier | 1.02459539 |
| 72 | MP0005195_abnormal_posterior_eye | 1.02402356 |
| 73 | MP0000613_abnormal_salivary_gland | 0.98979916 |
| 74 | MP0002405_respiratory_system_inflammati | 0.98820944 |
| 75 | MP0002733_abnormal_thermal_nociception | 0.97939223 |
| 76 | MP0004133_heterotaxia | 0.97704733 |
| 77 | MP0000427_abnormal_hair_cycle | 0.97551705 |
| 78 | MP0003786_premature_aging | 0.96403761 |
| 79 | MP0002693_abnormal_pancreas_physiology | 0.94439783 |
| 80 | MP0005636_abnormal_mineral_homeostasis | 0.93713124 |
| 81 | MP0003646_muscle_fatigue | 0.92108662 |
| 82 | MP0009333_abnormal_splenocyte_physiolog | 0.92028628 |
| 83 | MP0003880_abnormal_central_pattern | 0.91849281 |
| 84 | MP0005000_abnormal_immune_tolerance | 0.91203731 |
| 85 | MP0003123_paternal_imprinting | 0.87925055 |
| 86 | MP0008058_abnormal_DNA_repair | 0.87398060 |
| 87 | MP0002928_abnormal_bile_duct | 0.85421245 |
| 88 | MP0003567_abnormal_fetal_cardiomyocyte | 0.84599762 |
| 89 | MP0005423_abnormal_somatic_nervous | 0.84089246 |
| 90 | MP0001765_abnormal_ion_homeostasis | 0.83080444 |
| 91 | MP0003724_increased_susceptibility_to | 0.79361249 |
| 92 | MP0008789_abnormal_olfactory_epithelium | 0.79065608 |
| 93 | MP0005174_abnormal_tail_pigmentation | 0.78799809 |
| 94 | MP0001970_abnormal_pain_threshold | 0.78511798 |
| 95 | MP0002210_abnormal_sex_determination | 0.78233115 |
| 96 | MP0005332_abnormal_amino_acid | 0.77049380 |
| 97 | MP0000230_abnormal_systemic_arterial | 0.76528356 |
| 98 | MP0002557_abnormal_social/conspecific_i | 0.76203188 |
| 99 | MP0003936_abnormal_reproductive_system | 0.74880825 |
| 100 | MP0003879_abnormal_hair_cell | 0.74842328 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Molar tooth sign on MRI (HP:0002419) | 4.50459742 |
| 2 | Abnormality of midbrain morphology (HP:0002418) | 4.50459742 |
| 3 | Pancreatic fibrosis (HP:0100732) | 4.15185488 |
| 4 | Pancreatic cysts (HP:0001737) | 3.67834248 |
| 5 | Stomatitis (HP:0010280) | 3.61984398 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 3.57203695 |
| 7 | Increased hepatocellular lipid droplets (HP:0006565) | 3.56310490 |
| 8 | Nephronophthisis (HP:0000090) | 3.51277827 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.49773876 |
| 10 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 3.45216191 |
| 11 | Asplenia (HP:0001746) | 3.29431921 |
| 12 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.29023193 |
| 13 | Absent/shortened dynein arms (HP:0200106) | 3.29023193 |
| 14 | Acute encephalopathy (HP:0006846) | 3.23406405 |
| 15 | True hermaphroditism (HP:0010459) | 3.23214483 |
| 16 | Mitochondrial inheritance (HP:0001427) | 3.19647204 |
| 17 | Medial flaring of the eyebrow (HP:0010747) | 3.14672693 |
| 18 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.10104601 |
| 19 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.09413323 |
| 20 | Progressive macrocephaly (HP:0004481) | 2.97701502 |
| 21 | Increased CSF lactate (HP:0002490) | 2.97277087 |
| 22 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.95781485 |
| 23 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.95781485 |
| 24 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.92068974 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 2.91744472 |
| 26 | Abnormality of the renal medulla (HP:0100957) | 2.84313536 |
| 27 | Chronic hepatic failure (HP:0100626) | 2.74217182 |
| 28 | Supernumerary spleens (HP:0009799) | 2.73124471 |
| 29 | Renal Fanconi syndrome (HP:0001994) | 2.73121866 |
| 30 | Reticulocytopenia (HP:0001896) | 2.72817664 |
| 31 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.65753298 |
| 32 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.64830921 |
| 33 | Abnormality of the renal cortex (HP:0011035) | 2.63141762 |
| 34 | Congenital stationary night blindness (HP:0007642) | 2.56300870 |
| 35 | IgG deficiency (HP:0004315) | 2.55957112 |
| 36 | Pendular nystagmus (HP:0012043) | 2.49116704 |
| 37 | Methylmalonic acidemia (HP:0002912) | 2.48080952 |
| 38 | Large for gestational age (HP:0001520) | 2.47512693 |
| 39 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.42183786 |
| 40 | Abolished electroretinogram (ERG) (HP:0000550) | 2.41156666 |
| 41 | Increased serum lactate (HP:0002151) | 2.37885549 |
| 42 | Macrocytic anemia (HP:0001972) | 2.33707693 |
| 43 | Abnormal number of erythroid precursors (HP:0012131) | 2.33611654 |
| 44 | Optic disc pallor (HP:0000543) | 2.33186029 |
| 45 | Gait imbalance (HP:0002141) | 2.31895511 |
| 46 | Tubular atrophy (HP:0000092) | 2.31299772 |
| 47 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.28098147 |
| 48 | Polydipsia (HP:0001959) | 2.25785151 |
| 49 | Abnormal drinking behavior (HP:0030082) | 2.25785151 |
| 50 | Congenital primary aphakia (HP:0007707) | 2.25320766 |
| 51 | Increased intramyocellular lipid droplets (HP:0012240) | 2.25059930 |
| 52 | Cerebral edema (HP:0002181) | 2.24985157 |
| 53 | Hepatic necrosis (HP:0002605) | 2.24366538 |
| 54 | Abnormal pupillary function (HP:0007686) | 2.18811133 |
| 55 | Hepatocellular necrosis (HP:0001404) | 2.16080290 |
| 56 | Abnormal ciliary motility (HP:0012262) | 2.15555677 |
| 57 | Cystic liver disease (HP:0006706) | 2.15211404 |
| 58 | Median cleft lip (HP:0000161) | 2.14525654 |
| 59 | Constricted visual fields (HP:0001133) | 2.14425605 |
| 60 | Congenital hepatic fibrosis (HP:0002612) | 2.08270812 |
| 61 | Hypomagnesemia (HP:0002917) | 2.07472579 |
| 62 | Colon cancer (HP:0003003) | 2.06800983 |
| 63 | Abnormality of renal resorption (HP:0011038) | 2.05762205 |
| 64 | Nephrogenic diabetes insipidus (HP:0009806) | 2.04695570 |
| 65 | Type II lissencephaly (HP:0007260) | 2.04233489 |
| 66 | Abnormality of the labia minora (HP:0012880) | 2.04168321 |
| 67 | Abnormality of the pons (HP:0007361) | 2.03768579 |
| 68 | Postaxial foot polydactyly (HP:0001830) | 2.02911290 |
| 69 | Renal cortical cysts (HP:0000803) | 2.01291479 |
| 70 | Stenosis of the external auditory canal (HP:0000402) | 2.00483076 |
| 71 | Exertional dyspnea (HP:0002875) | 1.99204030 |
| 72 | Increased muscle lipid content (HP:0009058) | 1.98616256 |
| 73 | Methylmalonic aciduria (HP:0012120) | 1.98457210 |
| 74 | Male pseudohermaphroditism (HP:0000037) | 1.97751139 |
| 75 | Attenuation of retinal blood vessels (HP:0007843) | 1.96379394 |
| 76 | Glycosuria (HP:0003076) | 1.96049257 |
| 77 | Abnormality of urine glucose concentration (HP:0011016) | 1.96049257 |
| 78 | Lactic acidosis (HP:0003128) | 1.95900336 |
| 79 | Abnormal biliary tract physiology (HP:0012439) | 1.94747223 |
| 80 | Bile duct proliferation (HP:0001408) | 1.94747223 |
| 81 | Inability to walk (HP:0002540) | 1.94263896 |
| 82 | Type 2 muscle fiber atrophy (HP:0003554) | 1.92820062 |
| 83 | Postaxial hand polydactyly (HP:0001162) | 1.92722540 |
| 84 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.92566983 |
| 85 | Septo-optic dysplasia (HP:0100842) | 1.92120681 |
| 86 | Keratoconus (HP:0000563) | 1.90061551 |
| 87 | Increased corneal curvature (HP:0100692) | 1.90061551 |
| 88 | Tachypnea (HP:0002789) | 1.89808939 |
| 89 | Hyperglycinemia (HP:0002154) | 1.89328038 |
| 90 | Polyuria (HP:0000103) | 1.88567349 |
| 91 | Papilledema (HP:0001085) | 1.86714093 |
| 92 | Exercise intolerance (HP:0003546) | 1.85937801 |
| 93 | Decreased central vision (HP:0007663) | 1.84133834 |
| 94 | Absent thumb (HP:0009777) | 1.81856811 |
| 95 | Confusion (HP:0001289) | 1.81190720 |
| 96 | Sclerocornea (HP:0000647) | 1.79108669 |
| 97 | Lethargy (HP:0001254) | 1.78180317 |
| 98 | Chronic sinusitis (HP:0011109) | 1.76846088 |
| 99 | Optic nerve coloboma (HP:0000588) | 1.74072312 |
| 100 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.73679236 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TIE1 | 3.23892829 |
| 2 | TNIK | 3.03118801 |
| 3 | NUAK1 | 2.89772414 |
| 4 | TLK1 | 2.70732318 |
| 5 | TXK | 2.58490702 |
| 6 | WNK4 | 2.57533577 |
| 7 | FRK | 2.57301632 |
| 8 | GRK1 | 2.51202272 |
| 9 | TAOK3 | 2.49879544 |
| 10 | MAP3K12 | 2.35012815 |
| 11 | VRK2 | 2.26085081 |
| 12 | DYRK2 | 2.20935278 |
| 13 | STK16 | 2.17263471 |
| 14 | ZAK | 2.13154659 |
| 15 | ADRBK2 | 2.07525406 |
| 16 | WNK3 | 1.99959855 |
| 17 | MAP4K2 | 1.93933986 |
| 18 | BCKDK | 1.93385450 |
| 19 | STK39 | 1.75569573 |
| 20 | TSSK6 | 1.75201163 |
| 21 | TEC | 1.64521783 |
| 22 | NEK1 | 1.59001411 |
| 23 | MST4 | 1.55680755 |
| 24 | TAF1 | 1.53238253 |
| 25 | NME1 | 1.47837852 |
| 26 | BMPR1B | 1.46211516 |
| 27 | PIK3CA | 1.34259967 |
| 28 | PHKG2 | 1.27876599 |
| 29 | PHKG1 | 1.27876599 |
| 30 | ITK | 1.21526948 |
| 31 | VRK1 | 1.18547434 |
| 32 | EIF2AK3 | 1.18525440 |
| 33 | MAP2K6 | 1.14310042 |
| 34 | PLK3 | 1.03995283 |
| 35 | PASK | 1.03409373 |
| 36 | OXSR1 | 1.01382566 |
| 37 | PRKCQ | 0.99782956 |
| 38 | DAPK2 | 0.99482870 |
| 39 | MKNK1 | 0.98703371 |
| 40 | ACVR1B | 0.95895341 |
| 41 | KIT | 0.94303397 |
| 42 | PRKD3 | 0.91942487 |
| 43 | PRKCG | 0.90972473 |
| 44 | PBK | 0.84862454 |
| 45 | IKBKB | 0.83574441 |
| 46 | LIMK1 | 0.82027957 |
| 47 | PINK1 | 0.81183113 |
| 48 | NLK | 0.81053111 |
| 49 | PAK3 | 0.78768392 |
| 50 | MAPKAPK5 | 0.78329730 |
| 51 | PTK2B | 0.77207935 |
| 52 | DAPK1 | 0.75942600 |
| 53 | FES | 0.73836835 |
| 54 | EIF2AK1 | 0.73028748 |
| 55 | TRIM28 | 0.71697760 |
| 56 | ADRBK1 | 0.70613567 |
| 57 | INSRR | 0.70510445 |
| 58 | PLK2 | 0.66707298 |
| 59 | WNK1 | 0.66274507 |
| 60 | PRKCH | 0.65525885 |
| 61 | TGFBR1 | 0.61612225 |
| 62 | NME2 | 0.61433014 |
| 63 | EIF2AK2 | 0.61146994 |
| 64 | BTK | 0.60966251 |
| 65 | TNK2 | 0.60765485 |
| 66 | MAPK13 | 0.60459718 |
| 67 | CSNK1G1 | 0.58379079 |
| 68 | CSNK1G2 | 0.57116491 |
| 69 | CSNK1A1L | 0.53982264 |
| 70 | PRKCE | 0.51682615 |
| 71 | CSNK1G3 | 0.51617181 |
| 72 | MAP3K11 | 0.50286942 |
| 73 | GRK5 | 0.50178165 |
| 74 | MAPK15 | 0.48467176 |
| 75 | RPS6KA6 | 0.45613056 |
| 76 | CSNK2A2 | 0.44298657 |
| 77 | PRKACA | 0.43058851 |
| 78 | STK3 | 0.42863862 |
| 79 | CAMKK2 | 0.42524937 |
| 80 | LRRK2 | 0.42195976 |
| 81 | GRK7 | 0.41361952 |
| 82 | PAK6 | 0.41250259 |
| 83 | SYK | 0.40551669 |
| 84 | MAP4K1 | 0.40135943 |
| 85 | CDC7 | 0.39964433 |
| 86 | DAPK3 | 0.39890709 |
| 87 | PRKCI | 0.39818986 |
| 88 | LYN | 0.39580655 |
| 89 | OBSCN | 0.39556446 |
| 90 | ATR | 0.38041189 |
| 91 | CDK19 | 0.37865463 |
| 92 | MAP3K4 | 0.37555229 |
| 93 | MKNK2 | 0.36338685 |
| 94 | STK38L | 0.36219326 |
| 95 | MAP2K2 | 0.35274734 |
| 96 | PIM1 | 0.34475760 |
| 97 | CSNK2A1 | 0.34373631 |
| 98 | LCK | 0.33562210 |
| 99 | CAMK2D | 0.33369446 |
| 100 | CAMK2A | 0.33291325 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.05051590 |
| 2 | Protein export_Homo sapiens_hsa03060 | 3.36812834 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.99043102 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 2.97279968 |
| 5 | Asthma_Homo sapiens_hsa05310 | 2.50567936 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.31807965 |
| 7 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.27544977 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.19160703 |
| 9 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.14621641 |
| 10 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.09123542 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.08174025 |
| 12 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.00163009 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 1.99945958 |
| 14 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.98647380 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.89212859 |
| 16 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.88242941 |
| 17 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.82966557 |
| 18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.78665330 |
| 19 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.77854814 |
| 20 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.76313397 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.75494043 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.75265702 |
| 23 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.72343717 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.66237848 |
| 25 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.56061306 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.51664789 |
| 27 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.50875851 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.45825510 |
| 29 | Alzheimers disease_Homo sapiens_hsa05010 | 1.45143543 |
| 30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.44621679 |
| 31 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.43971850 |
| 32 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.39857444 |
| 33 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.29404782 |
| 34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.27912343 |
| 35 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.27026198 |
| 36 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.22727575 |
| 37 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.22713254 |
| 38 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.12927466 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.12127803 |
| 40 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.09968473 |
| 41 | RNA transport_Homo sapiens_hsa03013 | 1.09167761 |
| 42 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.06329489 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.05183990 |
| 44 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.04917512 |
| 45 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.03707582 |
| 46 | Peroxisome_Homo sapiens_hsa04146 | 1.01684992 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.01607544 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.00803590 |
| 49 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.96514090 |
| 50 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.96382510 |
| 51 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95044264 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.93551193 |
| 53 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.91198519 |
| 54 | Purine metabolism_Homo sapiens_hsa00230 | 0.91063368 |
| 55 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.85203899 |
| 56 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.85025826 |
| 57 | Homologous recombination_Homo sapiens_hsa03440 | 0.84103512 |
| 58 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.80292976 |
| 59 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.79122805 |
| 60 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.77095774 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.75192397 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.69093232 |
| 63 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68895532 |
| 64 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68682829 |
| 65 | Mismatch repair_Homo sapiens_hsa03430 | 0.68574547 |
| 66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.68379896 |
| 67 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68117805 |
| 68 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67514339 |
| 69 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.67196192 |
| 70 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.65890638 |
| 71 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.64455685 |
| 72 | Sulfur relay system_Homo sapiens_hsa04122 | 0.61900959 |
| 73 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61007574 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.57582401 |
| 75 | Retinol metabolism_Homo sapiens_hsa00830 | 0.57152032 |
| 76 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54835268 |
| 77 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.54660565 |
| 78 | Mineral absorption_Homo sapiens_hsa04978 | 0.54237210 |
| 79 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.53833919 |
| 80 | Spliceosome_Homo sapiens_hsa03040 | 0.49144713 |
| 81 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.47645136 |
| 82 | Insulin secretion_Homo sapiens_hsa04911 | 0.46923534 |
| 83 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.46737060 |
| 84 | Base excision repair_Homo sapiens_hsa03410 | 0.46206512 |
| 85 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.45048047 |
| 86 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.42561421 |
| 87 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40576930 |
| 88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.40261634 |
| 89 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.37649446 |
| 90 | Morphine addiction_Homo sapiens_hsa05032 | 0.37230296 |
| 91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.36724704 |
| 92 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.36394630 |
| 93 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.35954656 |
| 94 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.34480680 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.32381170 |
| 96 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.31863468 |
| 97 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.31231392 |
| 98 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.31108782 |
| 99 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.29895052 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29196356 |

