

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.77157339 |
| 2 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.44961393 |
| 3 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.44961393 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.10659857 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.10659857 |
| 6 | protein neddylation (GO:0045116) | 3.98426998 |
| 7 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.91291486 |
| 8 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.82867978 |
| 9 | chaperone-mediated protein transport (GO:0072321) | 3.81775812 |
| 10 | cytidine metabolic process (GO:0046087) | 3.79505453 |
| 11 | cytidine catabolic process (GO:0006216) | 3.79505453 |
| 12 | cytidine deamination (GO:0009972) | 3.79505453 |
| 13 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.79179123 |
| 14 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.71222040 |
| 15 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.65745692 |
| 16 | protein deneddylation (GO:0000338) | 3.63296822 |
| 17 | proteasome assembly (GO:0043248) | 3.62167570 |
| 18 | respiratory chain complex IV assembly (GO:0008535) | 3.56135063 |
| 19 | protein complex biogenesis (GO:0070271) | 3.55363317 |
| 20 | cullin deneddylation (GO:0010388) | 3.53927173 |
| 21 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.37047732 |
| 22 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.34636532 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.30003382 |
| 24 | cytochrome complex assembly (GO:0017004) | 3.29364520 |
| 25 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.27919544 |
| 26 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.25567478 |
| 27 | platelet dense granule organization (GO:0060155) | 3.18781109 |
| 28 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.17014347 |
| 29 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.11599176 |
| 30 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.11599176 |
| 31 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.11599176 |
| 32 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.11378610 |
| 33 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.11181863 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.10135587 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 3.10135587 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.10135587 |
| 37 | L-fucose catabolic process (GO:0042355) | 3.09189960 |
| 38 | fucose catabolic process (GO:0019317) | 3.09189960 |
| 39 | L-fucose metabolic process (GO:0042354) | 3.09189960 |
| 40 | ribosomal small subunit assembly (GO:0000028) | 3.05254555 |
| 41 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.04651358 |
| 42 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.04651358 |
| 43 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.00827156 |
| 44 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.00571403 |
| 45 | termination of RNA polymerase III transcription (GO:0006386) | 3.00571403 |
| 46 | iron-sulfur cluster assembly (GO:0016226) | 3.00035692 |
| 47 | metallo-sulfur cluster assembly (GO:0031163) | 3.00035692 |
| 48 | DNA double-strand break processing (GO:0000729) | 2.97417070 |
| 49 | response to pheromone (GO:0019236) | 2.96210833 |
| 50 | pseudouridine synthesis (GO:0001522) | 2.93020181 |
| 51 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.92924128 |
| 52 | mannosylation (GO:0097502) | 2.92447177 |
| 53 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.92276753 |
| 54 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.91770181 |
| 55 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.91770181 |
| 56 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.91743662 |
| 57 | tRNA processing (GO:0008033) | 2.91213311 |
| 58 | electron transport chain (GO:0022900) | 2.91205833 |
| 59 | respiratory electron transport chain (GO:0022904) | 2.90121664 |
| 60 | peptidyl-histidine modification (GO:0018202) | 2.90039546 |
| 61 | negative regulation of telomere maintenance (GO:0032205) | 2.90021822 |
| 62 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.89606716 |
| 63 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.89519556 |
| 64 | negative regulation of ligase activity (GO:0051352) | 2.89519556 |
| 65 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.87759483 |
| 66 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.87759483 |
| 67 | rRNA modification (GO:0000154) | 2.84547706 |
| 68 | GTP biosynthetic process (GO:0006183) | 2.83241278 |
| 69 | protein-cofactor linkage (GO:0018065) | 2.81478851 |
| 70 | GPI anchor metabolic process (GO:0006505) | 2.81211430 |
| 71 | base-excision repair, AP site formation (GO:0006285) | 2.78081303 |
| 72 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.76326916 |
| 73 | isotype switching (GO:0045190) | 2.76326916 |
| 74 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.76326916 |
| 75 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 2.73622592 |
| 76 | GPI anchor biosynthetic process (GO:0006506) | 2.73200716 |
| 77 | behavioral response to nicotine (GO:0035095) | 2.70104461 |
| 78 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.69026725 |
| 79 | maturation of 5.8S rRNA (GO:0000460) | 2.66079199 |
| 80 | S-adenosylmethionine metabolic process (GO:0046500) | 2.65968139 |
| 81 | branched-chain amino acid catabolic process (GO:0009083) | 2.64630552 |
| 82 | ubiquinone biosynthetic process (GO:0006744) | 2.63738301 |
| 83 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.62263617 |
| 84 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.61850068 |
| 85 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.61828449 |
| 86 | positive regulation of defense response to virus by host (GO:0002230) | 2.60277667 |
| 87 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.58985268 |
| 88 | aldehyde catabolic process (GO:0046185) | 2.56338362 |
| 89 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.54970273 |
| 90 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.54128189 |
| 91 | L-methionine biosynthetic process (GO:0071265) | 2.53215707 |
| 92 | amino acid salvage (GO:0043102) | 2.53215707 |
| 93 | L-methionine salvage (GO:0071267) | 2.53215707 |
| 94 | positive regulation of ligase activity (GO:0051351) | 2.52746191 |
| 95 | ATP biosynthetic process (GO:0006754) | 2.51325476 |
| 96 | tRNA modification (GO:0006400) | 2.50505027 |
| 97 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 2.49991252 |
| 98 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.49888830 |
| 99 | tRNA metabolic process (GO:0006399) | 2.49691234 |
| 100 | translation (GO:0006412) | 2.49153824 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.22980526 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.20087016 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.66093408 |
| 4 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.17819295 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.06922588 |
| 6 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.01364142 |
| 7 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.01162354 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.99566698 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.95185342 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.88539100 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.67354291 |
| 12 | VDR_22108803_ChIP-Seq_LS180_Human | 2.57777959 |
| 13 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.41318810 |
| 14 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.40708233 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.37061611 |
| 16 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.35212558 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.29271878 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.27012545 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.20513538 |
| 20 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.16561124 |
| 21 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.02974124 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.01358013 |
| 23 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.91993743 |
| 24 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.90401743 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.87453494 |
| 26 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.84902251 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.83483624 |
| 28 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.78479035 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.75296025 |
| 30 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.71144977 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.67678693 |
| 32 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.59517444 |
| 33 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.55709830 |
| 34 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.55083470 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.54164601 |
| 36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.53407876 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.51131459 |
| 38 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.47967328 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.45736127 |
| 40 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.45138134 |
| 41 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.44449703 |
| 42 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.42701733 |
| 43 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.38406343 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.37617233 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.36252202 |
| 46 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.36035541 |
| 47 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.35591308 |
| 48 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.34422648 |
| 49 | GATA3_26560356_Chip-Seq_TH2_Human | 1.29570936 |
| 50 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.28990801 |
| 51 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.27450313 |
| 52 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26459472 |
| 53 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25883309 |
| 54 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25883309 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.25668527 |
| 56 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.24061714 |
| 57 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23177454 |
| 58 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.22196841 |
| 59 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.21987487 |
| 60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21830880 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.21082349 |
| 62 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20306037 |
| 63 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.13626387 |
| 64 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.12605245 |
| 65 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.11845549 |
| 66 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.11800120 |
| 67 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11714804 |
| 68 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11714804 |
| 69 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.11570693 |
| 70 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11203377 |
| 71 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.11064023 |
| 72 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.10164863 |
| 73 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07518860 |
| 74 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.07157194 |
| 75 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.06566758 |
| 76 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.06566758 |
| 77 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.06543034 |
| 78 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.06289780 |
| 79 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05769928 |
| 80 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.02571093 |
| 81 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.02362978 |
| 82 | MYB_26560356_Chip-Seq_TH2_Human | 1.01811774 |
| 83 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.01121500 |
| 84 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.00479911 |
| 85 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.99875883 |
| 86 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.99497904 |
| 87 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98807575 |
| 88 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.97976914 |
| 89 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.96445521 |
| 90 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.96318876 |
| 91 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.96112200 |
| 92 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95614604 |
| 93 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.95462298 |
| 94 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.95359381 |
| 95 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94461900 |
| 96 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.94438672 |
| 97 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.94317376 |
| 98 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.93278380 |
| 99 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.91954477 |
| 100 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.90394825 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.36377373 |
| 2 | MP0008877_abnormal_DNA_methylation | 3.14485115 |
| 3 | MP0002102_abnormal_ear_morphology | 2.82778214 |
| 4 | MP0006072_abnormal_retinal_apoptosis | 2.72139098 |
| 5 | MP0004147_increased_porphyrin_level | 2.46611798 |
| 6 | MP0001835_abnormal_antigen_presentation | 2.42076023 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 2.41661564 |
| 8 | MP0008058_abnormal_DNA_repair | 2.40330959 |
| 9 | MP0003195_calcinosis | 2.15860738 |
| 10 | MP0005075_abnormal_melanosome_morpholog | 2.06848317 |
| 11 | MP0006292_abnormal_olfactory_placode | 2.02641348 |
| 12 | MP0003787_abnormal_imprinting | 1.99032522 |
| 13 | MP0009785_altered_susceptibility_to | 1.89650624 |
| 14 | MP0008872_abnormal_physiological_respon | 1.87408720 |
| 15 | MP0005645_abnormal_hypothalamus_physiol | 1.84590884 |
| 16 | MP0003786_premature_aging | 1.83343654 |
| 17 | MP0008875_abnormal_xenobiotic_pharmacok | 1.83309989 |
| 18 | MP0005084_abnormal_gallbladder_morpholo | 1.80266302 |
| 19 | MP0000372_irregular_coat_pigmentation | 1.78381308 |
| 20 | MP0003011_delayed_dark_adaptation | 1.76681002 |
| 21 | MP0002736_abnormal_nociception_after | 1.70620501 |
| 22 | MP0002837_dystrophic_cardiac_calcinosis | 1.70358737 |
| 23 | MP0003806_abnormal_nucleotide_metabolis | 1.66203286 |
| 24 | MP0005253_abnormal_eye_physiology | 1.62506303 |
| 25 | MP0002638_abnormal_pupillary_reflex | 1.60156282 |
| 26 | MP0001968_abnormal_touch/_nociception | 1.57330882 |
| 27 | MP0006036_abnormal_mitochondrial_physio | 1.51209698 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.48463292 |
| 29 | MP0008995_early_reproductive_senescence | 1.47314421 |
| 30 | MP0001986_abnormal_taste_sensitivity | 1.46211884 |
| 31 | MP0001800_abnormal_humoral_immune | 1.44261736 |
| 32 | MP0002876_abnormal_thyroid_physiology | 1.40031057 |
| 33 | MP0003724_increased_susceptibility_to | 1.37729030 |
| 34 | MP0005000_abnormal_immune_tolerance | 1.36191404 |
| 35 | MP0002166_altered_tumor_susceptibility | 1.35327230 |
| 36 | MP0002163_abnormal_gland_morphology | 1.34583535 |
| 37 | MP0003646_muscle_fatigue | 1.33718986 |
| 38 | MP0003763_abnormal_thymus_physiology | 1.32872385 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.32654122 |
| 40 | MP0005646_abnormal_pituitary_gland | 1.31646109 |
| 41 | MP0000685_abnormal_immune_system | 1.29710665 |
| 42 | MP0004142_abnormal_muscle_tone | 1.28981867 |
| 43 | MP0002006_tumorigenesis | 1.26970239 |
| 44 | MP0009333_abnormal_splenocyte_physiolog | 1.24425852 |
| 45 | MP0001529_abnormal_vocalization | 1.22888311 |
| 46 | MP0001764_abnormal_homeostasis | 1.22223199 |
| 47 | MP0003866_abnormal_defecation | 1.21080692 |
| 48 | MP0001873_stomach_inflammation | 1.20788088 |
| 49 | MP0002277_abnormal_respiratory_mucosa | 1.20704353 |
| 50 | MP0004145_abnormal_muscle_electrophysio | 1.20464244 |
| 51 | MP0005377_hearing/vestibular/ear_phenot | 1.20084223 |
| 52 | MP0003878_abnormal_ear_physiology | 1.20084223 |
| 53 | MP0002723_abnormal_immune_serum | 1.18035687 |
| 54 | MP0003880_abnormal_central_pattern | 1.17790938 |
| 55 | MP0001905_abnormal_dopamine_level | 1.17008124 |
| 56 | MP0005389_reproductive_system_phenotype | 1.15355293 |
| 57 | MP0003718_maternal_effect | 1.13582852 |
| 58 | MP0008789_abnormal_olfactory_epithelium | 1.12597040 |
| 59 | MP0001790_abnormal_immune_system | 1.12458865 |
| 60 | MP0005387_immune_system_phenotype | 1.12458865 |
| 61 | MP0002420_abnormal_adaptive_immunity | 1.12265498 |
| 62 | MP0001819_abnormal_immune_cell | 1.11013992 |
| 63 | MP0010094_abnormal_chromosome_stability | 1.10329295 |
| 64 | MP0001984_abnormal_olfaction | 1.09545715 |
| 65 | MP0002938_white_spotting | 1.09466916 |
| 66 | MP0003693_abnormal_embryo_hatching | 1.09123346 |
| 67 | MP0001919_abnormal_reproductive_system | 1.09094484 |
| 68 | MP0004043_abnormal_pH_regulation | 1.08941699 |
| 69 | MP0006276_abnormal_autonomic_nervous | 1.08812610 |
| 70 | MP0009764_decreased_sensitivity_to | 1.06741371 |
| 71 | MP0003186_abnormal_redox_activity | 1.05770183 |
| 72 | MP0005360_urolithiasis | 1.05198268 |
| 73 | MP0004885_abnormal_endolymph | 1.04117951 |
| 74 | MP0001501_abnormal_sleep_pattern | 1.04100761 |
| 75 | MP0005379_endocrine/exocrine_gland_phen | 1.02649943 |
| 76 | MP0005332_abnormal_amino_acid | 1.02051839 |
| 77 | MP0001188_hyperpigmentation | 1.01591710 |
| 78 | MP0002452_abnormal_antigen_presenting | 1.01304781 |
| 79 | MP0000689_abnormal_spleen_morphology | 0.98110642 |
| 80 | MP0006035_abnormal_mitochondrial_morpho | 0.97956018 |
| 81 | MP0010155_abnormal_intestine_physiology | 0.94416682 |
| 82 | MP0005636_abnormal_mineral_homeostasis | 0.93996642 |
| 83 | MP0002254_reproductive_system_inflammat | 0.92328459 |
| 84 | MP0008007_abnormal_cellular_replicative | 0.91402296 |
| 85 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89844536 |
| 86 | MP0002398_abnormal_bone_marrow | 0.87414504 |
| 87 | MP0002751_abnormal_autonomic_nervous | 0.87381782 |
| 88 | MP0001845_abnormal_inflammatory_respons | 0.85169058 |
| 89 | MP0000716_abnormal_immune_system | 0.85037060 |
| 90 | MP0005025_abnormal_response_to | 0.84616941 |
| 91 | MP0002160_abnormal_reproductive_system | 0.82458864 |
| 92 | MP0000516_abnormal_urinary_system | 0.80938116 |
| 93 | MP0005367_renal/urinary_system_phenotyp | 0.80938116 |
| 94 | MP0002272_abnormal_nervous_system | 0.80562223 |
| 95 | MP0001485_abnormal_pinna_reflex | 0.78941722 |
| 96 | MP0005085_abnormal_gallbladder_physiolo | 0.78526319 |
| 97 | MP0001119_abnormal_female_reproductive | 0.78434354 |
| 98 | MP0002234_abnormal_pharynx_morphology | 0.78317469 |
| 99 | MP0002722_abnormal_immune_system | 0.75987278 |
| 100 | MP0000703_abnormal_thymus_morphology | 0.75474289 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.79806552 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.63527856 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.43673519 |
| 4 | Increased CSF lactate (HP:0002490) | 3.41947971 |
| 5 | Acute encephalopathy (HP:0006846) | 3.39647823 |
| 6 | 3-Methylglutaconic aciduria (HP:0003535) | 3.36262052 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.34521887 |
| 8 | IgG deficiency (HP:0004315) | 3.33495187 |
| 9 | Pancreatic cysts (HP:0001737) | 3.29179555 |
| 10 | Methylmalonic acidemia (HP:0002912) | 3.29043464 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.28388720 |
| 12 | Hepatic necrosis (HP:0002605) | 3.13777338 |
| 13 | Increased hepatocellular lipid droplets (HP:0006565) | 3.04026374 |
| 14 | Methylmalonic aciduria (HP:0012120) | 2.93051984 |
| 15 | Severe combined immunodeficiency (HP:0004430) | 2.89918222 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.89020394 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 2.82736052 |
| 18 | Congenital stationary night blindness (HP:0007642) | 2.76357436 |
| 19 | Abolished electroretinogram (ERG) (HP:0000550) | 2.74040019 |
| 20 | Pancreatic fibrosis (HP:0100732) | 2.66927784 |
| 21 | True hermaphroditism (HP:0010459) | 2.66262926 |
| 22 | Stomatitis (HP:0010280) | 2.64639036 |
| 23 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.61844612 |
| 24 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.61844612 |
| 25 | Increased serum lactate (HP:0002151) | 2.61799375 |
| 26 | Molar tooth sign on MRI (HP:0002419) | 2.61286954 |
| 27 | Abnormality of midbrain morphology (HP:0002418) | 2.61286954 |
| 28 | Cerebral edema (HP:0002181) | 2.58062838 |
| 29 | Aplastic anemia (HP:0001915) | 2.56979354 |
| 30 | Lactic acidosis (HP:0003128) | 2.50765602 |
| 31 | Increased intramyocellular lipid droplets (HP:0012240) | 2.48019488 |
| 32 | Thyroiditis (HP:0100646) | 2.47737098 |
| 33 | Renal Fanconi syndrome (HP:0001994) | 2.44183468 |
| 34 | Hypoproteinemia (HP:0003075) | 2.41598493 |
| 35 | Hyperglycinemia (HP:0002154) | 2.38489295 |
| 36 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.37932032 |
| 37 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.35977999 |
| 38 | Abnormality of alanine metabolism (HP:0010916) | 2.34761420 |
| 39 | Hyperalaninemia (HP:0003348) | 2.34761420 |
| 40 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.34761420 |
| 41 | Abnormality of vitamin B metabolism (HP:0004340) | 2.32043332 |
| 42 | Hypothermia (HP:0002045) | 2.31549802 |
| 43 | Optic disc pallor (HP:0000543) | 2.29225876 |
| 44 | Nephronophthisis (HP:0000090) | 2.28748160 |
| 45 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.26540690 |
| 46 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.26438588 |
| 47 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.25074863 |
| 48 | Exertional dyspnea (HP:0002875) | 2.24460598 |
| 49 | Attenuation of retinal blood vessels (HP:0007843) | 2.23017306 |
| 50 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.22800112 |
| 51 | Combined immunodeficiency (HP:0005387) | 2.22242405 |
| 52 | Abnormality of serum amino acid levels (HP:0003112) | 2.21296235 |
| 53 | Medial flaring of the eyebrow (HP:0010747) | 2.21170699 |
| 54 | Type I transferrin isoform profile (HP:0003642) | 2.21081075 |
| 55 | Type 2 muscle fiber atrophy (HP:0003554) | 2.19340047 |
| 56 | Lethargy (HP:0001254) | 2.18568229 |
| 57 | Pendular nystagmus (HP:0012043) | 2.16272419 |
| 58 | Colon cancer (HP:0003003) | 2.15604016 |
| 59 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.13902734 |
| 60 | Abnormality of the labia minora (HP:0012880) | 2.10900636 |
| 61 | Dicarboxylic aciduria (HP:0003215) | 2.10581552 |
| 62 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.10581552 |
| 63 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.08925855 |
| 64 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.08368050 |
| 65 | Abnormality of glycine metabolism (HP:0010895) | 2.08368050 |
| 66 | Congenital, generalized hypertrichosis (HP:0004540) | 2.07758517 |
| 67 | Abnormality of the renal cortex (HP:0011035) | 2.07215402 |
| 68 | Renal cortical cysts (HP:0000803) | 2.04672832 |
| 69 | Abnormality of eosinophils (HP:0001879) | 2.03549475 |
| 70 | Increased muscle lipid content (HP:0009058) | 2.02421333 |
| 71 | Abnormality of T cells (HP:0002843) | 2.01738550 |
| 72 | Abnormal protein glycosylation (HP:0012346) | 2.01223766 |
| 73 | Abnormal glycosylation (HP:0012345) | 2.01223766 |
| 74 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.01223766 |
| 75 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.01223766 |
| 76 | T lymphocytopenia (HP:0005403) | 2.00346125 |
| 77 | Abnormality of B cell number (HP:0010975) | 2.00076488 |
| 78 | Abnormality of the pons (HP:0007361) | 1.98074319 |
| 79 | Delayed CNS myelination (HP:0002188) | 1.97546276 |
| 80 | Respiratory failure (HP:0002878) | 1.97326462 |
| 81 | Pancytopenia (HP:0001876) | 1.95594609 |
| 82 | Abnormality of T cell number (HP:0011839) | 1.94700741 |
| 83 | Panhypogammaglobulinemia (HP:0003139) | 1.92606567 |
| 84 | Hypoplasia of the pons (HP:0012110) | 1.92598524 |
| 85 | Abnormal biliary tract physiology (HP:0012439) | 1.91971172 |
| 86 | Bile duct proliferation (HP:0001408) | 1.91971172 |
| 87 | Abnormality of the prostate (HP:0008775) | 1.91189270 |
| 88 | B lymphocytopenia (HP:0010976) | 1.90628143 |
| 89 | Glycosuria (HP:0003076) | 1.87406320 |
| 90 | Abnormality of urine glucose concentration (HP:0011016) | 1.87406320 |
| 91 | Abnormality of the renal medulla (HP:0100957) | 1.84472778 |
| 92 | Hypomagnesemia (HP:0002917) | 1.84345782 |
| 93 | Ketosis (HP:0001946) | 1.83600381 |
| 94 | Decreased central vision (HP:0007663) | 1.80683649 |
| 95 | Hyperglycinuria (HP:0003108) | 1.80102488 |
| 96 | Exercise intolerance (HP:0003546) | 1.79574892 |
| 97 | Ketoacidosis (HP:0001993) | 1.78119089 |
| 98 | Cerebral palsy (HP:0100021) | 1.77141085 |
| 99 | Generalized aminoaciduria (HP:0002909) | 1.76101257 |
| 100 | Sclerocornea (HP:0000647) | 1.75009521 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K2 | 3.63960062 |
| 2 | TXK | 3.16520752 |
| 3 | ZAK | 3.08570980 |
| 4 | NUAK1 | 2.75795891 |
| 5 | FRK | 2.64925908 |
| 6 | TAOK3 | 2.57372708 |
| 7 | VRK2 | 2.44141743 |
| 8 | BCKDK | 2.42509990 |
| 9 | TRIM28 | 2.17211305 |
| 10 | TLK1 | 2.15367967 |
| 11 | ADRBK2 | 2.11769339 |
| 12 | WNK3 | 2.07140410 |
| 13 | MST4 | 2.04578565 |
| 14 | GRK1 | 1.95640770 |
| 15 | KDR | 1.89251763 |
| 16 | STK16 | 1.88025164 |
| 17 | EIF2AK3 | 1.78892520 |
| 18 | SRPK1 | 1.75835636 |
| 19 | CDK19 | 1.69634411 |
| 20 | BMPR1B | 1.61382473 |
| 21 | PASK | 1.48128726 |
| 22 | VRK1 | 1.47757059 |
| 23 | BUB1 | 1.46872293 |
| 24 | TIE1 | 1.42059122 |
| 25 | TSSK6 | 1.40453957 |
| 26 | MAP4K1 | 1.38440755 |
| 27 | WNK4 | 1.30772404 |
| 28 | MKNK1 | 1.26635209 |
| 29 | ACVR1B | 1.24490164 |
| 30 | PLK3 | 1.19167977 |
| 31 | MKNK2 | 1.14659571 |
| 32 | OXSR1 | 1.13178932 |
| 33 | TEC | 1.08077567 |
| 34 | PINK1 | 1.07927469 |
| 35 | ERBB3 | 1.07755597 |
| 36 | FES | 1.07739238 |
| 37 | IKBKB | 1.05690943 |
| 38 | DYRK2 | 1.03918678 |
| 39 | CSNK1G3 | 1.03255016 |
| 40 | ITK | 1.02827226 |
| 41 | NME1 | 1.02352304 |
| 42 | CSNK1G1 | 1.01162265 |
| 43 | RPS6KA4 | 0.99224381 |
| 44 | BCR | 0.98127800 |
| 45 | INSRR | 0.95787628 |
| 46 | TESK2 | 0.94921415 |
| 47 | TNIK | 0.91289291 |
| 48 | GRK6 | 0.87315278 |
| 49 | MAP3K4 | 0.85205872 |
| 50 | CSNK1G2 | 0.83721240 |
| 51 | IKBKE | 0.83621017 |
| 52 | RPS6KA5 | 0.81799110 |
| 53 | PLK4 | 0.80028500 |
| 54 | DAPK1 | 0.79397828 |
| 55 | KIT | 0.77670631 |
| 56 | FLT3 | 0.74920681 |
| 57 | TGFBR1 | 0.71476913 |
| 58 | NEK1 | 0.70117000 |
| 59 | LIMK1 | 0.69398176 |
| 60 | MAPK13 | 0.68615360 |
| 61 | CSNK1A1L | 0.68293815 |
| 62 | MAP3K12 | 0.67956133 |
| 63 | NLK | 0.67849090 |
| 64 | PLK2 | 0.67496893 |
| 65 | SYK | 0.66893801 |
| 66 | MUSK | 0.65512954 |
| 67 | PRKCQ | 0.64524801 |
| 68 | LCK | 0.63719680 |
| 69 | PHKG2 | 0.62280886 |
| 70 | PHKG1 | 0.62280886 |
| 71 | ATR | 0.61987702 |
| 72 | LYN | 0.58787226 |
| 73 | MAP2K6 | 0.58225109 |
| 74 | PLK1 | 0.55565865 |
| 75 | PRKCE | 0.52648238 |
| 76 | EIF2AK2 | 0.52430168 |
| 77 | MAP2K7 | 0.51344951 |
| 78 | ADRBK1 | 0.50797188 |
| 79 | CDC7 | 0.50524351 |
| 80 | CSF1R | 0.49093400 |
| 81 | STK39 | 0.47917233 |
| 82 | CSNK2A1 | 0.47158099 |
| 83 | PRKCG | 0.42897596 |
| 84 | BMPR2 | 0.42823189 |
| 85 | MAPKAPK3 | 0.42524192 |
| 86 | CSNK1A1 | 0.42327816 |
| 87 | PIK3CA | 0.39900269 |
| 88 | IGF1R | 0.38827688 |
| 89 | DAPK2 | 0.38381575 |
| 90 | MAP2K2 | 0.38137146 |
| 91 | CSNK2A2 | 0.37774530 |
| 92 | PIM1 | 0.37191771 |
| 93 | BTK | 0.37130603 |
| 94 | MYLK | 0.36139508 |
| 95 | SIK3 | 0.32961215 |
| 96 | EIF2AK1 | 0.32604388 |
| 97 | PRKCA | 0.32226249 |
| 98 | TNK2 | 0.30808477 |
| 99 | PAK3 | 0.30450995 |
| 100 | AURKB | 0.30299370 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.93833640 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.94480295 |
| 3 | Protein export_Homo sapiens_hsa03060 | 2.80750468 |
| 4 | Asthma_Homo sapiens_hsa05310 | 2.53501869 |
| 5 | Ribosome_Homo sapiens_hsa03010 | 2.52310236 |
| 6 | Parkinsons disease_Homo sapiens_hsa05012 | 2.42609369 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.38747699 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.37825370 |
| 9 | RNA polymerase_Homo sapiens_hsa03020 | 2.35525932 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.27996152 |
| 11 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.19117051 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.16093296 |
| 13 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13309050 |
| 14 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.00219827 |
| 15 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.73331485 |
| 16 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.72820775 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.72694529 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.71665096 |
| 19 | Homologous recombination_Homo sapiens_hsa03440 | 1.60516106 |
| 20 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.60397243 |
| 21 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.54844712 |
| 22 | Phototransduction_Homo sapiens_hsa04744 | 1.45480556 |
| 23 | Huntingtons disease_Homo sapiens_hsa05016 | 1.45078445 |
| 24 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.44868491 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.41837805 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.39906318 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.38915794 |
| 28 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.34975684 |
| 29 | Basal transcription factors_Homo sapiens_hsa03022 | 1.34853259 |
| 30 | Mismatch repair_Homo sapiens_hsa03430 | 1.34825053 |
| 31 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.30736868 |
| 32 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.28103308 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.28085416 |
| 34 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.24119727 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.22545494 |
| 36 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.20822220 |
| 37 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.20126683 |
| 38 | Spliceosome_Homo sapiens_hsa03040 | 1.17511025 |
| 39 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.16084554 |
| 40 | RNA transport_Homo sapiens_hsa03013 | 1.12690548 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.11871249 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11543419 |
| 43 | DNA replication_Homo sapiens_hsa03030 | 1.11533682 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.10718127 |
| 45 | Peroxisome_Homo sapiens_hsa04146 | 1.09566535 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.08838663 |
| 47 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.07431367 |
| 48 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.07256369 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 1.05177703 |
| 50 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.05100671 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.98859317 |
| 52 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.96202033 |
| 53 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.94097272 |
| 54 | Base excision repair_Homo sapiens_hsa03410 | 0.92898204 |
| 55 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.92840860 |
| 56 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.91590809 |
| 57 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.90297599 |
| 58 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.89762784 |
| 59 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.89574291 |
| 60 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.89406625 |
| 61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.84141307 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.78832734 |
| 63 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.77948146 |
| 64 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77889393 |
| 65 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.76470233 |
| 66 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.73352362 |
| 67 | Viral myocarditis_Homo sapiens_hsa05416 | 0.71104064 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69791781 |
| 69 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.69064578 |
| 70 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.68290687 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.67487867 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64599713 |
| 73 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.62714256 |
| 74 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.61627318 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.61021267 |
| 76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.60883954 |
| 77 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.60713884 |
| 78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.60553268 |
| 79 | Sulfur relay system_Homo sapiens_hsa04122 | 0.56977988 |
| 80 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56584013 |
| 81 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.55898081 |
| 82 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55818719 |
| 83 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.54013229 |
| 84 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.53774353 |
| 85 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.49463515 |
| 86 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.47218158 |
| 87 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.46578427 |
| 88 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.42165407 |
| 89 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.42106915 |
| 90 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.41368058 |
| 91 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.40965928 |
| 92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.40909560 |
| 93 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39875611 |
| 94 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.34357329 |
| 95 | Nicotine addiction_Homo sapiens_hsa05033 | 0.33686947 |
| 96 | Taste transduction_Homo sapiens_hsa04742 | 0.33635120 |
| 97 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.32210595 |
| 98 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.30450851 |
| 99 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29209154 |
| 100 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29100989 |

