

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 5.93869393 |
| 2 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.12339172 |
| 3 | ATP synthesis coupled proton transport (GO:0015986) | 4.57202464 |
| 4 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.57202464 |
| 5 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.18705891 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 4.16794922 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.00900015 |
| 8 | chaperone-mediated protein transport (GO:0072321) | 3.86091994 |
| 9 | proteasome assembly (GO:0043248) | 3.82745071 |
| 10 | cytidine metabolic process (GO:0046087) | 3.79971569 |
| 11 | cytidine catabolic process (GO:0006216) | 3.79971569 |
| 12 | cytidine deamination (GO:0009972) | 3.79971569 |
| 13 | protein complex biogenesis (GO:0070271) | 3.75571000 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.74879865 |
| 15 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.73080067 |
| 16 | maturation of 5.8S rRNA (GO:0000460) | 3.65925071 |
| 17 | protein neddylation (GO:0045116) | 3.65094228 |
| 18 | rRNA modification (GO:0000154) | 3.61286376 |
| 19 | response to pheromone (GO:0019236) | 3.56162679 |
| 20 | ribosomal large subunit biogenesis (GO:0042273) | 3.51717485 |
| 21 | cullin deneddylation (GO:0010388) | 3.49562664 |
| 22 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.48410384 |
| 23 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.44093072 |
| 24 | NADH dehydrogenase complex assembly (GO:0010257) | 3.44093072 |
| 25 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.44093072 |
| 26 | termination of RNA polymerase III transcription (GO:0006386) | 3.36253943 |
| 27 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.36253943 |
| 28 | electron transport chain (GO:0022900) | 3.34825985 |
| 29 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.34634761 |
| 30 | respiratory electron transport chain (GO:0022904) | 3.33324248 |
| 31 | positive regulation of prostaglandin secretion (GO:0032308) | 3.31000623 |
| 32 | protein-cofactor linkage (GO:0018065) | 3.26220540 |
| 33 | pseudouridine synthesis (GO:0001522) | 3.23299061 |
| 34 | protein deneddylation (GO:0000338) | 3.23116832 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.20562147 |
| 36 | aldehyde catabolic process (GO:0046185) | 3.19940547 |
| 37 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.17766290 |
| 38 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.14395893 |
| 39 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.12902627 |
| 40 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.09282501 |
| 41 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.06948592 |
| 42 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.06948592 |
| 43 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.06948592 |
| 44 | fucose catabolic process (GO:0019317) | 3.06678063 |
| 45 | L-fucose metabolic process (GO:0042354) | 3.06678063 |
| 46 | L-fucose catabolic process (GO:0042355) | 3.06678063 |
| 47 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.02668457 |
| 48 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.02668457 |
| 49 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.98629785 |
| 50 | respiratory chain complex IV assembly (GO:0008535) | 2.95961170 |
| 51 | maturation of SSU-rRNA (GO:0030490) | 2.94382774 |
| 52 | indolalkylamine catabolic process (GO:0046218) | 2.92355874 |
| 53 | tryptophan catabolic process (GO:0006569) | 2.92355874 |
| 54 | indole-containing compound catabolic process (GO:0042436) | 2.92355874 |
| 55 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.91367917 |
| 56 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.91367917 |
| 57 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.87964987 |
| 58 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.87885446 |
| 59 | GTP biosynthetic process (GO:0006183) | 2.87368378 |
| 60 | cytochrome complex assembly (GO:0017004) | 2.85061533 |
| 61 | piRNA metabolic process (GO:0034587) | 2.84721304 |
| 62 | vitamin biosynthetic process (GO:0009110) | 2.83179892 |
| 63 | ubiquinone biosynthetic process (GO:0006744) | 2.81470110 |
| 64 | viral transcription (GO:0019083) | 2.78128629 |
| 65 | rRNA methylation (GO:0031167) | 2.76283448 |
| 66 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.76268485 |
| 67 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.76268485 |
| 68 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.74500444 |
| 69 | tRNA processing (GO:0008033) | 2.74060696 |
| 70 | negative regulation of ligase activity (GO:0051352) | 2.74058231 |
| 71 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.74058231 |
| 72 | tryptophan metabolic process (GO:0006568) | 2.71744487 |
| 73 | indolalkylamine metabolic process (GO:0006586) | 2.70968970 |
| 74 | response to interferon-beta (GO:0035456) | 2.70671407 |
| 75 | translation (GO:0006412) | 2.69064302 |
| 76 | translational elongation (GO:0006414) | 2.68902218 |
| 77 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.67113851 |
| 78 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.66215959 |
| 79 | translational termination (GO:0006415) | 2.65977305 |
| 80 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.65659078 |
| 81 | behavioral response to nicotine (GO:0035095) | 2.64755808 |
| 82 | protein targeting to ER (GO:0045047) | 2.63773830 |
| 83 | cotranslational protein targeting to membrane (GO:0006613) | 2.63421331 |
| 84 | kynurenine metabolic process (GO:0070189) | 2.62485862 |
| 85 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.59561695 |
| 86 | ATP biosynthetic process (GO:0006754) | 2.58803510 |
| 87 | rRNA catabolic process (GO:0016075) | 2.58147275 |
| 88 | cellular component biogenesis (GO:0044085) | 2.58070837 |
| 89 | regulation of prostaglandin secretion (GO:0032306) | 2.56887989 |
| 90 | intracellular protein transmembrane import (GO:0044743) | 2.54646952 |
| 91 | regulation of chronic inflammatory response (GO:0002676) | 2.52656268 |
| 92 | protein localization to endoplasmic reticulum (GO:0070972) | 2.51759271 |
| 93 | immunoglobulin mediated immune response (GO:0016064) | 2.50634753 |
| 94 | hydrogen ion transmembrane transport (GO:1902600) | 2.50119596 |
| 95 | ubiquinone metabolic process (GO:0006743) | 2.49384968 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.49106830 |
| 97 | phosphatidylinositol acyl-chain remodeling (GO:0036149) | 2.48890011 |
| 98 | negative regulation of telomere maintenance (GO:0032205) | 2.47198769 |
| 99 | hydrogen transport (GO:0006818) | 2.47046448 |
| 100 | proton transport (GO:0015992) | 2.47001615 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.55086203 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.12832943 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.95698472 |
| 4 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.95548866 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.33745126 |
| 6 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.16643912 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.97006519 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.91479344 |
| 9 | VDR_22108803_ChIP-Seq_LS180_Human | 2.83065331 |
| 10 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.81060420 |
| 11 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.72408255 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.56179236 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.50331174 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.49652391 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.47091755 |
| 16 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.43834824 |
| 17 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.27445987 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.20678640 |
| 19 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.20466336 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.20008601 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.14865071 |
| 22 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.03913166 |
| 23 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.92714671 |
| 24 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.91104648 |
| 25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.90891429 |
| 26 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.81947294 |
| 27 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.76262707 |
| 28 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.76148776 |
| 29 | EWS_26573619_Chip-Seq_HEK293_Human | 1.69905107 |
| 30 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.64464170 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.63296785 |
| 32 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.59068274 |
| 33 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.58584993 |
| 34 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.52615007 |
| 35 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.49442688 |
| 36 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.48810418 |
| 37 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.45093603 |
| 38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.43236385 |
| 39 | AR_20517297_ChIP-Seq_VCAP_Human | 1.41355931 |
| 40 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.40976048 |
| 41 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.40976048 |
| 42 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.39894645 |
| 43 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.38325228 |
| 44 | GATA3_26560356_Chip-Seq_TH2_Human | 1.32925739 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.31258521 |
| 46 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.28489204 |
| 47 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.27669665 |
| 48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.27307594 |
| 49 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.26794005 |
| 50 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.25428724 |
| 51 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.24371955 |
| 52 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.24125680 |
| 53 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.20541350 |
| 54 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.16786491 |
| 55 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.16642140 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.16041361 |
| 57 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.15300889 |
| 58 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.14953620 |
| 59 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.13392261 |
| 60 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.13329024 |
| 61 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.13329024 |
| 62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12695919 |
| 63 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.12325451 |
| 64 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.12256082 |
| 65 | NCOR_22424771_ChIP-Seq_293T_Human | 1.11134482 |
| 66 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.10840704 |
| 67 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.10271066 |
| 68 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.09204654 |
| 69 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.08790835 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.08151526 |
| 71 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.08120819 |
| 72 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.08117005 |
| 73 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.07817310 |
| 74 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.06848030 |
| 75 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.04976859 |
| 76 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04891367 |
| 77 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.03775939 |
| 78 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.03465847 |
| 79 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.03430255 |
| 80 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02506899 |
| 81 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.02005636 |
| 82 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.99195738 |
| 83 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98833516 |
| 84 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98257231 |
| 85 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.97483879 |
| 86 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97323035 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96836419 |
| 88 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.96294584 |
| 89 | P300_19829295_ChIP-Seq_ESCs_Human | 0.96252213 |
| 90 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.96195126 |
| 91 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.96195126 |
| 92 | DCP1A_22483619_ChIP-Seq_HELA_Human | 0.95842753 |
| 93 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.95344510 |
| 94 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.95233606 |
| 95 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95163774 |
| 96 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.94162747 |
| 97 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92535468 |
| 98 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.92353501 |
| 99 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.91573226 |
| 100 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.90860797 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002138_abnormal_hepatobiliary_system | 3.30287505 |
| 2 | MP0005084_abnormal_gallbladder_morpholo | 2.99927120 |
| 3 | MP0001835_abnormal_antigen_presentation | 2.74018725 |
| 4 | MP0003806_abnormal_nucleotide_metabolis | 2.60345786 |
| 5 | MP0008875_abnormal_xenobiotic_pharmacok | 2.48703652 |
| 6 | MP0005671_abnormal_response_to | 2.48331919 |
| 7 | MP0008872_abnormal_physiological_respon | 2.35982691 |
| 8 | MP0008058_abnormal_DNA_repair | 2.34062258 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.17176786 |
| 10 | MP0000685_abnormal_immune_system | 2.15672150 |
| 11 | MP0002102_abnormal_ear_morphology | 2.11035105 |
| 12 | MP0004147_increased_porphyrin_level | 2.02245967 |
| 13 | MP0003195_calcinosis | 1.92547977 |
| 14 | MP0003252_abnormal_bile_duct | 1.88333864 |
| 15 | MP0006292_abnormal_olfactory_placode | 1.87742360 |
| 16 | MP0000372_irregular_coat_pigmentation | 1.85563744 |
| 17 | MP0002876_abnormal_thyroid_physiology | 1.82340696 |
| 18 | MP0002166_altered_tumor_susceptibility | 1.80259395 |
| 19 | MP0005645_abnormal_hypothalamus_physiol | 1.76393536 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.72581972 |
| 21 | MP0001800_abnormal_humoral_immune | 1.71391114 |
| 22 | MP0002148_abnormal_hypersensitivity_rea | 1.69493409 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.66462488 |
| 24 | MP0005075_abnormal_melanosome_morpholog | 1.64278920 |
| 25 | MP0009785_altered_susceptibility_to | 1.63840733 |
| 26 | MP0002006_tumorigenesis | 1.63463560 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.58962115 |
| 28 | MP0001873_stomach_inflammation | 1.57023463 |
| 29 | MP0005085_abnormal_gallbladder_physiolo | 1.56530773 |
| 30 | MP0005167_abnormal_blood-brain_barrier | 1.56249891 |
| 31 | MP0003786_premature_aging | 1.55825434 |
| 32 | MP0003718_maternal_effect | 1.55766909 |
| 33 | MP0001790_abnormal_immune_system | 1.48545848 |
| 34 | MP0005387_immune_system_phenotype | 1.48545848 |
| 35 | MP0006036_abnormal_mitochondrial_physio | 1.47015614 |
| 36 | MP0001986_abnormal_taste_sensitivity | 1.44528858 |
| 37 | MP0003186_abnormal_redox_activity | 1.42174447 |
| 38 | MP0002139_abnormal_hepatobiliary_system | 1.42114683 |
| 39 | MP0005360_urolithiasis | 1.42099607 |
| 40 | MP0009764_decreased_sensitivity_to | 1.40759701 |
| 41 | MP0004885_abnormal_endolymph | 1.39996257 |
| 42 | MP0005551_abnormal_eye_electrophysiolog | 1.38279555 |
| 43 | MP0001764_abnormal_homeostasis | 1.36713954 |
| 44 | MP0001905_abnormal_dopamine_level | 1.36080749 |
| 45 | MP0003866_abnormal_defecation | 1.34977845 |
| 46 | MP0002736_abnormal_nociception_after | 1.34870790 |
| 47 | MP0005000_abnormal_immune_tolerance | 1.33598943 |
| 48 | MP0002723_abnormal_immune_serum | 1.32695745 |
| 49 | MP0003011_delayed_dark_adaptation | 1.30595350 |
| 50 | MP0010155_abnormal_intestine_physiology | 1.30476314 |
| 51 | MP0009379_abnormal_foot_pigmentation | 1.29438423 |
| 52 | MP0004142_abnormal_muscle_tone | 1.28920657 |
| 53 | MP0001501_abnormal_sleep_pattern | 1.27672247 |
| 54 | MP0002452_abnormal_antigen_presenting | 1.26186307 |
| 55 | MP0003646_muscle_fatigue | 1.25582771 |
| 56 | MP0002277_abnormal_respiratory_mucosa | 1.23143908 |
| 57 | MP0003724_increased_susceptibility_to | 1.21686270 |
| 58 | MP0002928_abnormal_bile_duct | 1.21158521 |
| 59 | MP0002234_abnormal_pharynx_morphology | 1.19576219 |
| 60 | MP0005389_reproductive_system_phenotype | 1.16616076 |
| 61 | MP0009333_abnormal_splenocyte_physiolog | 1.16093228 |
| 62 | MP0002420_abnormal_adaptive_immunity | 1.13740916 |
| 63 | MP0008775_abnormal_heart_ventricle | 1.13503379 |
| 64 | MP0001819_abnormal_immune_cell | 1.13356257 |
| 65 | MP0005636_abnormal_mineral_homeostasis | 1.13137089 |
| 66 | MP0005410_abnormal_fertilization | 1.10888640 |
| 67 | MP0004145_abnormal_muscle_electrophysio | 1.08274422 |
| 68 | MP0003693_abnormal_embryo_hatching | 1.06761354 |
| 69 | MP0002160_abnormal_reproductive_system | 1.03812612 |
| 70 | MP0002837_dystrophic_cardiac_calcinosis | 1.03504287 |
| 71 | MP0003787_abnormal_imprinting | 1.02363372 |
| 72 | MP0009697_abnormal_copulation | 1.00986017 |
| 73 | MP0001845_abnormal_inflammatory_respons | 0.99686168 |
| 74 | MP0008007_abnormal_cellular_replicative | 0.99649173 |
| 75 | MP0002272_abnormal_nervous_system | 0.95207861 |
| 76 | MP0005332_abnormal_amino_acid | 0.95204306 |
| 77 | MP0003638_abnormal_response/metabolism_ | 0.91088663 |
| 78 | MP0005025_abnormal_response_to | 0.91034131 |
| 79 | MP0001919_abnormal_reproductive_system | 0.89802796 |
| 80 | MP0001293_anophthalmia | 0.89572126 |
| 81 | MP0006035_abnormal_mitochondrial_morpho | 0.89280579 |
| 82 | MP0000230_abnormal_systemic_arterial | 0.89121375 |
| 83 | MP0005253_abnormal_eye_physiology | 0.88473871 |
| 84 | MP0005365_abnormal_bile_salt | 0.87753726 |
| 85 | MP0009643_abnormal_urine_homeostasis | 0.86952006 |
| 86 | MP0008469_abnormal_protein_level | 0.84739475 |
| 87 | MP0006082_CNS_inflammation | 0.84401558 |
| 88 | MP0001663_abnormal_digestive_system | 0.84094379 |
| 89 | MP0004019_abnormal_vitamin_homeostasis | 0.83301648 |
| 90 | MP0000716_abnormal_immune_system | 0.82825765 |
| 91 | MP0002163_abnormal_gland_morphology | 0.82031526 |
| 92 | MP0005319_abnormal_enzyme/_coenzyme | 0.81519714 |
| 93 | MP0000689_abnormal_spleen_morphology | 0.79513767 |
| 94 | MP0002398_abnormal_bone_marrow | 0.77706966 |
| 95 | MP0002733_abnormal_thermal_nociception | 0.77647883 |
| 96 | MP0001765_abnormal_ion_homeostasis | 0.76932434 |
| 97 | MP0004043_abnormal_pH_regulation | 0.76580944 |
| 98 | MP0010094_abnormal_chromosome_stability | 0.75191518 |
| 99 | MP0003436_decreased_susceptibility_to | 0.74949653 |
| 100 | MP0002638_abnormal_pupillary_reflex | 0.72892936 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.32216907 |
| 2 | Mitochondrial inheritance (HP:0001427) | 4.05784257 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.00907713 |
| 4 | Increased CSF lactate (HP:0002490) | 3.95217761 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.86108598 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.80816788 |
| 7 | Acute encephalopathy (HP:0006846) | 3.79636329 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.64430127 |
| 9 | Lipid accumulation in hepatocytes (HP:0006561) | 3.63639285 |
| 10 | Hepatic necrosis (HP:0002605) | 3.40868260 |
| 11 | IgG deficiency (HP:0004315) | 3.20674932 |
| 12 | Renal Fanconi syndrome (HP:0001994) | 3.17010024 |
| 13 | Stomatitis (HP:0010280) | 3.15542358 |
| 14 | Cerebral edema (HP:0002181) | 3.04142081 |
| 15 | Abolished electroretinogram (ERG) (HP:0000550) | 3.03695030 |
| 16 | Methylmalonic aciduria (HP:0012120) | 2.99084769 |
| 17 | Increased serum lactate (HP:0002151) | 2.98891252 |
| 18 | Pancreatic cysts (HP:0001737) | 2.96768208 |
| 19 | Congenital stationary night blindness (HP:0007642) | 2.84567463 |
| 20 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.81329211 |
| 21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.77770841 |
| 22 | Methylmalonic acidemia (HP:0002912) | 2.75317986 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 2.71895831 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.66741294 |
| 25 | Colon cancer (HP:0003003) | 2.65804803 |
| 26 | Hypoproteinemia (HP:0003075) | 2.65246346 |
| 27 | Lactic acidosis (HP:0003128) | 2.59519828 |
| 28 | Increased intramyocellular lipid droplets (HP:0012240) | 2.59366564 |
| 29 | Optic disc pallor (HP:0000543) | 2.55676094 |
| 30 | Abnormality of the renal cortex (HP:0011035) | 2.51659390 |
| 31 | Lethargy (HP:0001254) | 2.51314043 |
| 32 | Abnormal number of erythroid precursors (HP:0012131) | 2.45846437 |
| 33 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.43055802 |
| 34 | Exertional dyspnea (HP:0002875) | 2.40091294 |
| 35 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.39893693 |
| 36 | IgM deficiency (HP:0002850) | 2.38275498 |
| 37 | Respiratory failure (HP:0002878) | 2.34124606 |
| 38 | Abnormality of the prostate (HP:0008775) | 2.33709609 |
| 39 | Abnormality of urine glucose concentration (HP:0011016) | 2.32268810 |
| 40 | Glycosuria (HP:0003076) | 2.32268810 |
| 41 | Pendular nystagmus (HP:0012043) | 2.30255074 |
| 42 | Attenuation of retinal blood vessels (HP:0007843) | 2.29497280 |
| 43 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.28914549 |
| 44 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.26911019 |
| 45 | Abnormal drinking behavior (HP:0030082) | 2.26783954 |
| 46 | Polydipsia (HP:0001959) | 2.26783954 |
| 47 | Congenital, generalized hypertrichosis (HP:0004540) | 2.26172840 |
| 48 | True hermaphroditism (HP:0010459) | 2.24347608 |
| 49 | Abnormality of midbrain morphology (HP:0002418) | 2.23759357 |
| 50 | Molar tooth sign on MRI (HP:0002419) | 2.23759357 |
| 51 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.20774062 |
| 52 | Bile duct proliferation (HP:0001408) | 2.19442477 |
| 53 | Abnormal biliary tract physiology (HP:0012439) | 2.19442477 |
| 54 | Increased muscle lipid content (HP:0009058) | 2.19436567 |
| 55 | Dicarboxylic aciduria (HP:0003215) | 2.19132184 |
| 56 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.19132184 |
| 57 | Renal cortical cysts (HP:0000803) | 2.18619714 |
| 58 | Large for gestational age (HP:0001520) | 2.17874953 |
| 59 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.16796141 |
| 60 | Type II lissencephaly (HP:0007260) | 2.14388277 |
| 61 | Panhypogammaglobulinemia (HP:0003139) | 2.14105948 |
| 62 | Abnormality of B cell number (HP:0010975) | 2.11809698 |
| 63 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.10895734 |
| 64 | Abnormality of T cell physiology (HP:0011840) | 2.10172163 |
| 65 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.10144653 |
| 66 | CNS demyelination (HP:0007305) | 2.10034967 |
| 67 | Nephronophthisis (HP:0000090) | 2.09067619 |
| 68 | Hyperglycinemia (HP:0002154) | 2.08169328 |
| 69 | Keratoconus (HP:0000563) | 2.07853885 |
| 70 | Increased corneal curvature (HP:0100692) | 2.07853885 |
| 71 | Exercise intolerance (HP:0003546) | 2.03518849 |
| 72 | Abnormality of renal resorption (HP:0011038) | 2.01333374 |
| 73 | Stomach cancer (HP:0012126) | 2.00468584 |
| 74 | Reticulocytopenia (HP:0001896) | 1.99699085 |
| 75 | Asplenia (HP:0001746) | 1.99337365 |
| 76 | Decreased central vision (HP:0007663) | 1.97995914 |
| 77 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.96207500 |
| 78 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.96207500 |
| 79 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.95658725 |
| 80 | Tubular atrophy (HP:0000092) | 1.95116016 |
| 81 | Leukodystrophy (HP:0002415) | 1.94009049 |
| 82 | Abnormality of the renal medulla (HP:0100957) | 1.92114891 |
| 83 | Ketosis (HP:0001946) | 1.91629441 |
| 84 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.88359351 |
| 85 | Abnormality of glycine metabolism (HP:0010895) | 1.88359351 |
| 86 | Respiratory difficulties (HP:0002880) | 1.87141191 |
| 87 | Pancytopenia (HP:0001876) | 1.86921494 |
| 88 | Absent thumb (HP:0009777) | 1.86805038 |
| 89 | Increased IgM level (HP:0003496) | 1.86339372 |
| 90 | Hypothermia (HP:0002045) | 1.85038122 |
| 91 | Polyuria (HP:0000103) | 1.84449237 |
| 92 | Thyroiditis (HP:0100646) | 1.83156926 |
| 93 | Abnormality of vitamin B metabolism (HP:0004340) | 1.82678588 |
| 94 | Hyperglycinuria (HP:0003108) | 1.82371681 |
| 95 | Abnormality of the pons (HP:0007361) | 1.82326382 |
| 96 | Abnormality of serum amino acid levels (HP:0003112) | 1.82218992 |
| 97 | Type 2 muscle fiber atrophy (HP:0003554) | 1.80975665 |
| 98 | Hypoplasia of the uterus (HP:0000013) | 1.79662728 |
| 99 | Abnormality of T cells (HP:0002843) | 1.79518677 |
| 100 | Severe combined immunodeficiency (HP:0004430) | 1.78988352 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 3.79819493 |
| 2 | NUAK1 | 3.73223262 |
| 3 | VRK2 | 3.59583811 |
| 4 | TIE1 | 3.21753628 |
| 5 | FRK | 3.10496318 |
| 6 | TAOK3 | 2.85521090 |
| 7 | ZAK | 2.82989856 |
| 8 | TLK1 | 2.77618793 |
| 9 | MAP4K2 | 2.67460732 |
| 10 | EIF2AK3 | 2.66267777 |
| 11 | GRK1 | 2.22090109 |
| 12 | VRK1 | 2.21629663 |
| 13 | ADRBK2 | 2.06328445 |
| 14 | BMPR1B | 1.93471822 |
| 15 | MST4 | 1.82659337 |
| 16 | TSSK6 | 1.76345121 |
| 17 | PINK1 | 1.67361103 |
| 18 | OXSR1 | 1.64297080 |
| 19 | MAPKAPK3 | 1.63736593 |
| 20 | TXK | 1.63014311 |
| 21 | WNK4 | 1.59947793 |
| 22 | TEC | 1.58334626 |
| 23 | BCKDK | 1.55663262 |
| 24 | EIF2AK1 | 1.33209798 |
| 25 | BUB1 | 1.32937784 |
| 26 | PLK3 | 1.32527965 |
| 27 | STK39 | 1.22425667 |
| 28 | FES | 1.21285426 |
| 29 | ACVR1B | 1.20995156 |
| 30 | TAF1 | 1.16000065 |
| 31 | MAPKAPK5 | 1.14336244 |
| 32 | ITK | 1.13205518 |
| 33 | KIT | 1.09846837 |
| 34 | IKBKB | 1.09575445 |
| 35 | MKNK1 | 1.03793884 |
| 36 | PBK | 0.98015729 |
| 37 | CDK19 | 0.97740503 |
| 38 | KDR | 0.96676603 |
| 39 | CSNK1G3 | 0.93422876 |
| 40 | PHKG2 | 0.92542908 |
| 41 | PHKG1 | 0.92542908 |
| 42 | GRK6 | 0.87926404 |
| 43 | SYK | 0.86277298 |
| 44 | MAP4K1 | 0.85403619 |
| 45 | TRIM28 | 0.83751478 |
| 46 | DAPK1 | 0.80718498 |
| 47 | PASK | 0.80656344 |
| 48 | WNK3 | 0.80606964 |
| 49 | INSRR | 0.79310933 |
| 50 | DYRK2 | 0.78777493 |
| 51 | TGFBR1 | 0.78304152 |
| 52 | CSNK1G1 | 0.78130604 |
| 53 | EIF2AK2 | 0.78021682 |
| 54 | PDK2 | 0.76477203 |
| 55 | PLK2 | 0.74779835 |
| 56 | RPS6KA5 | 0.71084042 |
| 57 | PIK3CG | 0.71035272 |
| 58 | MAP2K6 | 0.70909501 |
| 59 | MAPK15 | 0.70151323 |
| 60 | PLK4 | 0.67088261 |
| 61 | CSNK1G2 | 0.66135962 |
| 62 | CDK8 | 0.65797610 |
| 63 | IKBKE | 0.64998665 |
| 64 | TNIK | 0.62523470 |
| 65 | GRK5 | 0.60085044 |
| 66 | PRKCQ | 0.59441687 |
| 67 | CAMKK2 | 0.59438043 |
| 68 | BTK | 0.59036434 |
| 69 | CSNK1A1L | 0.57941430 |
| 70 | TRPM7 | 0.56345300 |
| 71 | LYN | 0.55037290 |
| 72 | MATK | 0.54771020 |
| 73 | BMPR2 | 0.53391176 |
| 74 | ERBB3 | 0.53321553 |
| 75 | NME1 | 0.50085813 |
| 76 | FGFR2 | 0.49927740 |
| 77 | DAPK2 | 0.48546922 |
| 78 | ADRBK1 | 0.46503348 |
| 79 | NME2 | 0.45314457 |
| 80 | LCK | 0.44141934 |
| 81 | LIMK1 | 0.43998381 |
| 82 | TNK2 | 0.42677931 |
| 83 | MYLK | 0.42432455 |
| 84 | CCNB1 | 0.41500973 |
| 85 | NLK | 0.40709202 |
| 86 | RPS6KB2 | 0.39827036 |
| 87 | SRPK1 | 0.38901818 |
| 88 | MKNK2 | 0.38327229 |
| 89 | MAPK13 | 0.37973154 |
| 90 | MAP3K14 | 0.36094099 |
| 91 | SCYL2 | 0.35754179 |
| 92 | MAP3K12 | 0.35611368 |
| 93 | CSNK2A2 | 0.35013539 |
| 94 | MAP2K2 | 0.35008905 |
| 95 | IGF1R | 0.34524055 |
| 96 | PIK3CA | 0.33605740 |
| 97 | CSNK2A1 | 0.33131957 |
| 98 | PRKCA | 0.32417934 |
| 99 | PRKCG | 0.31184761 |
| 100 | PTK2B | 0.30988222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.09760023 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.41859265 |
| 3 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.32037177 |
| 4 | Allograft rejection_Homo sapiens_hsa05330 | 3.26098082 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.14980563 |
| 6 | Ribosome_Homo sapiens_hsa03010 | 2.77544012 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.75742156 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.59532982 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.55637246 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.27665740 |
| 11 | RNA polymerase_Homo sapiens_hsa03020 | 2.25613837 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.13917061 |
| 13 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.77745618 |
| 14 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.73618183 |
| 15 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.67274125 |
| 16 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.62780106 |
| 17 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.59906985 |
| 18 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.58890119 |
| 19 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.58666520 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.52580207 |
| 21 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.47861031 |
| 22 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.45748004 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.45623392 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.39228955 |
| 25 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.39035235 |
| 26 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.36230503 |
| 27 | Alzheimers disease_Homo sapiens_hsa05010 | 1.35673921 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.27534716 |
| 29 | Mismatch repair_Homo sapiens_hsa03430 | 1.26808225 |
| 30 | Huntingtons disease_Homo sapiens_hsa05016 | 1.26489906 |
| 31 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.23852976 |
| 32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.23833452 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.18432896 |
| 34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.17861024 |
| 35 | Phototransduction_Homo sapiens_hsa04744 | 1.16630180 |
| 36 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.13771677 |
| 37 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.13660252 |
| 38 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.10458612 |
| 39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.08189389 |
| 40 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.05557538 |
| 41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.04140338 |
| 42 | Purine metabolism_Homo sapiens_hsa00230 | 1.03310795 |
| 43 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.01858737 |
| 44 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.01396607 |
| 45 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.99573297 |
| 46 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.98998309 |
| 47 | Basal transcription factors_Homo sapiens_hsa03022 | 0.98621147 |
| 48 | DNA replication_Homo sapiens_hsa03030 | 0.98084658 |
| 49 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.97609858 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.96416789 |
| 51 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.95408481 |
| 52 | Viral myocarditis_Homo sapiens_hsa05416 | 0.95175483 |
| 53 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92078452 |
| 54 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.88810982 |
| 55 | Base excision repair_Homo sapiens_hsa03410 | 0.87612158 |
| 56 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.87042448 |
| 57 | RNA transport_Homo sapiens_hsa03013 | 0.81703249 |
| 58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.81516640 |
| 59 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.77129723 |
| 60 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.73452986 |
| 61 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.73121833 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.73071107 |
| 63 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.72755146 |
| 64 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68369889 |
| 65 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.66782436 |
| 66 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.66334039 |
| 67 | Leishmaniasis_Homo sapiens_hsa05140 | 0.65959045 |
| 68 | Spliceosome_Homo sapiens_hsa03040 | 0.65650571 |
| 69 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64787225 |
| 70 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.63541024 |
| 71 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.62650774 |
| 72 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.61812653 |
| 73 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.61686844 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.60182696 |
| 75 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.59287058 |
| 76 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.59219293 |
| 77 | Metabolic pathways_Homo sapiens_hsa01100 | 0.58452779 |
| 78 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.56818748 |
| 79 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.56548941 |
| 80 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.55975962 |
| 81 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.52241002 |
| 82 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.51206736 |
| 83 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.49256413 |
| 84 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49053182 |
| 85 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.49030716 |
| 86 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45885342 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.44416943 |
| 88 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.43065839 |
| 89 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.42111847 |
| 90 | Sulfur relay system_Homo sapiens_hsa04122 | 0.40299251 |
| 91 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.38463085 |
| 92 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.37077074 |
| 93 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.36831031 |
| 94 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.36460303 |
| 95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.35544289 |
| 96 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.34561447 |
| 97 | Olfactory transduction_Homo sapiens_hsa04740 | 0.34051520 |
| 98 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.33377593 |
| 99 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.33068551 |
| 100 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.30705237 |

