

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.44433178 |
| 2 | ATP synthesis coupled proton transport (GO:0015986) | 5.19850444 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.19850444 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.04401248 |
| 5 | cytidine metabolic process (GO:0046087) | 4.85152749 |
| 6 | cytidine catabolic process (GO:0006216) | 4.85152749 |
| 7 | cytidine deamination (GO:0009972) | 4.85152749 |
| 8 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 4.63401701 |
| 9 | ribosomal small subunit assembly (GO:0000028) | 4.34002765 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.14509887 |
| 11 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.13399040 |
| 12 | protein complex biogenesis (GO:0070271) | 4.00238584 |
| 13 | respiratory electron transport chain (GO:0022904) | 3.86519455 |
| 14 | electron transport chain (GO:0022900) | 3.85231714 |
| 15 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.76028505 |
| 16 | protein neddylation (GO:0045116) | 3.73618502 |
| 17 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.67834503 |
| 18 | cytochrome complex assembly (GO:0017004) | 3.65876312 |
| 19 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.65786462 |
| 20 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.65786462 |
| 21 | respiratory chain complex IV assembly (GO:0008535) | 3.65416242 |
| 22 | viral transcription (GO:0019083) | 3.54341428 |
| 23 | chaperone-mediated protein transport (GO:0072321) | 3.52304296 |
| 24 | translational termination (GO:0006415) | 3.47513302 |
| 25 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.35864147 |
| 26 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.35439242 |
| 27 | NADH dehydrogenase complex assembly (GO:0010257) | 3.35439242 |
| 28 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.35439242 |
| 29 | positive regulation of defense response to virus by host (GO:0002230) | 3.32616066 |
| 30 | protein targeting to ER (GO:0045047) | 3.30243573 |
| 31 | cotranslational protein targeting to membrane (GO:0006613) | 3.29718030 |
| 32 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.26969814 |
| 33 | translational elongation (GO:0006414) | 3.22622515 |
| 34 | regulation of activation of Janus kinase activity (GO:0010533) | 3.21075725 |
| 35 | response to pheromone (GO:0019236) | 3.16185921 |
| 36 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.16020676 |
| 37 | protein localization to endoplasmic reticulum (GO:0070972) | 3.16012958 |
| 38 | platelet dense granule organization (GO:0060155) | 3.14816084 |
| 39 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.11503448 |
| 40 | ATP biosynthetic process (GO:0006754) | 3.09502493 |
| 41 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.08613849 |
| 42 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.07962483 |
| 43 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.07364682 |
| 44 | GTP biosynthetic process (GO:0006183) | 3.03085784 |
| 45 | proteasome assembly (GO:0043248) | 3.01811550 |
| 46 | hydrogen ion transmembrane transport (GO:1902600) | 3.00713765 |
| 47 | maturation of SSU-rRNA (GO:0030490) | 2.96434958 |
| 48 | regulation of regulatory T cell differentiation (GO:0045589) | 2.95838083 |
| 49 | behavioral response to nicotine (GO:0035095) | 2.94190168 |
| 50 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.94095939 |
| 51 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.94004767 |
| 52 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.92316091 |
| 53 | proton transport (GO:0015992) | 2.87406692 |
| 54 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.86810774 |
| 55 | translation (GO:0006412) | 2.86389661 |
| 56 | ribosomal small subunit biogenesis (GO:0042274) | 2.84632218 |
| 57 | pseudouridine synthesis (GO:0001522) | 2.83705932 |
| 58 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.83634723 |
| 59 | mannosylation (GO:0097502) | 2.83125786 |
| 60 | hydrogen transport (GO:0006818) | 2.81489684 |
| 61 | GPI anchor metabolic process (GO:0006505) | 2.81065589 |
| 62 | positive regulation of prostaglandin secretion (GO:0032308) | 2.72957197 |
| 63 | termination of RNA polymerase III transcription (GO:0006386) | 2.71466226 |
| 64 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.71466226 |
| 65 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.71115381 |
| 66 | actin nucleation (GO:0045010) | 2.68014515 |
| 67 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.67732641 |
| 68 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.66997792 |
| 69 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.66966493 |
| 70 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.66550120 |
| 71 | GPI anchor biosynthetic process (GO:0006506) | 2.66538821 |
| 72 | L-fucose catabolic process (GO:0042355) | 2.65749245 |
| 73 | fucose catabolic process (GO:0019317) | 2.65749245 |
| 74 | L-fucose metabolic process (GO:0042354) | 2.65749245 |
| 75 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.65684970 |
| 76 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.64526982 |
| 77 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.60678872 |
| 78 | negative regulation of T cell apoptotic process (GO:0070233) | 2.60475185 |
| 79 | regulation of memory T cell differentiation (GO:0043380) | 2.59871529 |
| 80 | cellular ketone body metabolic process (GO:0046950) | 2.59577327 |
| 81 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.58942247 |
| 82 | regulation of chronic inflammatory response (GO:0002676) | 2.58721600 |
| 83 | ribosomal large subunit biogenesis (GO:0042273) | 2.58661095 |
| 84 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.57681917 |
| 85 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.57681917 |
| 86 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.57681917 |
| 87 | viral life cycle (GO:0019058) | 2.57510841 |
| 88 | translational initiation (GO:0006413) | 2.56067141 |
| 89 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.55344177 |
| 90 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.55125361 |
| 91 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.55125361 |
| 92 | rRNA modification (GO:0000154) | 2.52421763 |
| 93 | cellular component biogenesis (GO:0044085) | 2.52392289 |
| 94 | peptidyl-histidine modification (GO:0018202) | 2.52365211 |
| 95 | cellular protein complex disassembly (GO:0043624) | 2.51203418 |
| 96 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.51117600 |
| 97 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.50976613 |
| 98 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 2.50269065 |
| 99 | positive regulation of fatty acid transport (GO:2000193) | 2.49891125 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.49195960 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.68009229 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.38457188 |
| 3 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 3.38274422 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.35379707 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.18705036 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.93050090 |
| 7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.80419260 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.79803002 |
| 9 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.72390946 |
| 10 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.66188322 |
| 11 | VDR_22108803_ChIP-Seq_LS180_Human | 2.62289656 |
| 12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.60749310 |
| 13 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.58866676 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.53920630 |
| 15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.37204556 |
| 16 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.36088403 |
| 17 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.34893533 |
| 18 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.29888137 |
| 19 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.15833316 |
| 20 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.99760500 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.98512220 |
| 22 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.92125185 |
| 23 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.84338354 |
| 24 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.83178529 |
| 25 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.78811536 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.76328165 |
| 27 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.76133836 |
| 28 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.74845203 |
| 29 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.63228672 |
| 30 | EWS_26573619_Chip-Seq_HEK293_Human | 1.56067149 |
| 31 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.54510365 |
| 32 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.53261992 |
| 33 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.52972158 |
| 34 | GATA3_26560356_Chip-Seq_TH2_Human | 1.50979676 |
| 35 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.47608459 |
| 36 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.47608459 |
| 37 | AR_20517297_ChIP-Seq_VCAP_Human | 1.43938471 |
| 38 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.41860882 |
| 39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39883813 |
| 40 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.32194059 |
| 41 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.30721143 |
| 42 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.29929467 |
| 43 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.29929467 |
| 44 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.28982719 |
| 45 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.26300192 |
| 46 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.25629729 |
| 47 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.25284755 |
| 48 | MYB_26560356_Chip-Seq_TH2_Human | 1.23622767 |
| 49 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23442054 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.23438670 |
| 51 | NCOR_22424771_ChIP-Seq_293T_Human | 1.23134133 |
| 52 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.22174178 |
| 53 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.20906945 |
| 54 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.20749377 |
| 55 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20613044 |
| 56 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.20368499 |
| 57 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.19576997 |
| 58 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.17975950 |
| 59 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16316947 |
| 60 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.15709087 |
| 61 | P300_19829295_ChIP-Seq_ESCs_Human | 1.15095416 |
| 62 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.14994014 |
| 63 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.14688776 |
| 64 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.14527388 |
| 65 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.14420783 |
| 66 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.13685241 |
| 67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.13556952 |
| 68 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.12213692 |
| 69 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.12055606 |
| 70 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.11540177 |
| 71 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.10098801 |
| 72 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.09738224 |
| 73 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.09738224 |
| 74 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.09325694 |
| 75 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.09174705 |
| 76 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.07671281 |
| 77 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.06772340 |
| 78 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.06644584 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06286726 |
| 80 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04954918 |
| 81 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.04729273 |
| 82 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.04441523 |
| 83 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.03533871 |
| 84 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02649364 |
| 85 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.02227081 |
| 86 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.00656312 |
| 87 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.00493860 |
| 88 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.99351277 |
| 89 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.99295945 |
| 90 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.98776993 |
| 91 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.98475399 |
| 92 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.97765565 |
| 93 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97498546 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.96303404 |
| 95 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.96036882 |
| 96 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.95742287 |
| 97 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95356182 |
| 98 | ERA_21632823_ChIP-Seq_H3396_Human | 0.94779953 |
| 99 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.94015292 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.93889769 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 3.92128200 |
| 2 | MP0001835_abnormal_antigen_presentation | 2.66097046 |
| 3 | MP0009379_abnormal_foot_pigmentation | 2.58185490 |
| 4 | MP0009785_altered_susceptibility_to | 2.40643490 |
| 5 | MP0006072_abnormal_retinal_apoptosis | 2.28035856 |
| 6 | MP0008877_abnormal_DNA_methylation | 2.24211936 |
| 7 | MP0002102_abnormal_ear_morphology | 2.21839255 |
| 8 | MP0002163_abnormal_gland_morphology | 2.18744379 |
| 9 | MP0005075_abnormal_melanosome_morpholog | 2.14286271 |
| 10 | MP0002837_dystrophic_cardiac_calcinosis | 2.11579345 |
| 11 | MP0005645_abnormal_hypothalamus_physiol | 2.11160362 |
| 12 | MP0003646_muscle_fatigue | 2.01947883 |
| 13 | MP0006292_abnormal_olfactory_placode | 2.01902509 |
| 14 | MP0008875_abnormal_xenobiotic_pharmacok | 2.01261395 |
| 15 | MP0002876_abnormal_thyroid_physiology | 1.89846157 |
| 16 | MP0002148_abnormal_hypersensitivity_rea | 1.87350334 |
| 17 | MP0005379_endocrine/exocrine_gland_phen | 1.85110103 |
| 18 | MP0004147_increased_porphyrin_level | 1.84010778 |
| 19 | MP0008872_abnormal_physiological_respon | 1.81523045 |
| 20 | MP0002638_abnormal_pupillary_reflex | 1.79978380 |
| 21 | MP0000372_irregular_coat_pigmentation | 1.74302553 |
| 22 | MP0003195_calcinosis | 1.74229186 |
| 23 | MP0005000_abnormal_immune_tolerance | 1.70980398 |
| 24 | MP0005646_abnormal_pituitary_gland | 1.70559644 |
| 25 | MP0005084_abnormal_gallbladder_morpholo | 1.68181939 |
| 26 | MP0003787_abnormal_imprinting | 1.67192100 |
| 27 | MP0003011_delayed_dark_adaptation | 1.66676194 |
| 28 | MP0001800_abnormal_humoral_immune | 1.64355188 |
| 29 | MP0009333_abnormal_splenocyte_physiolog | 1.63762803 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.63084776 |
| 31 | MP0005389_reproductive_system_phenotype | 1.60185845 |
| 32 | MP0003763_abnormal_thymus_physiology | 1.55201721 |
| 33 | MP0001919_abnormal_reproductive_system | 1.55085468 |
| 34 | MP0005253_abnormal_eye_physiology | 1.54190233 |
| 35 | MP0005551_abnormal_eye_electrophysiolog | 1.53967503 |
| 36 | MP0004145_abnormal_muscle_electrophysio | 1.47212475 |
| 37 | MP0000685_abnormal_immune_system | 1.45813262 |
| 38 | MP0002723_abnormal_immune_serum | 1.42739918 |
| 39 | MP0002138_abnormal_hepatobiliary_system | 1.39508615 |
| 40 | MP0002420_abnormal_adaptive_immunity | 1.37291996 |
| 41 | MP0005387_immune_system_phenotype | 1.37185348 |
| 42 | MP0001790_abnormal_immune_system | 1.37185348 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.34279239 |
| 44 | MP0001819_abnormal_immune_cell | 1.34067850 |
| 45 | MP0002006_tumorigenesis | 1.33838926 |
| 46 | MP0001905_abnormal_dopamine_level | 1.33774624 |
| 47 | MP0001873_stomach_inflammation | 1.33707593 |
| 48 | MP0003866_abnormal_defecation | 1.31703375 |
| 49 | MP0005025_abnormal_response_to | 1.30735569 |
| 50 | MP0004142_abnormal_muscle_tone | 1.29090978 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.28935712 |
| 52 | MP0002277_abnormal_respiratory_mucosa | 1.27887560 |
| 53 | MP0004885_abnormal_endolymph | 1.25765085 |
| 54 | MP0003786_premature_aging | 1.22815917 |
| 55 | MP0002736_abnormal_nociception_after | 1.22645194 |
| 56 | MP0001986_abnormal_taste_sensitivity | 1.21695240 |
| 57 | MP0002160_abnormal_reproductive_system | 1.21635818 |
| 58 | MP0002693_abnormal_pancreas_physiology | 1.19084195 |
| 59 | MP0002452_abnormal_antigen_presenting | 1.16171466 |
| 60 | MP0001764_abnormal_homeostasis | 1.16026715 |
| 61 | MP0002095_abnormal_skin_pigmentation | 1.15873249 |
| 62 | MP0010155_abnormal_intestine_physiology | 1.11580613 |
| 63 | MP0005636_abnormal_mineral_homeostasis | 1.06825365 |
| 64 | MP0008058_abnormal_DNA_repair | 1.04377577 |
| 65 | MP0001845_abnormal_inflammatory_respons | 1.04220139 |
| 66 | MP0009764_decreased_sensitivity_to | 1.03656427 |
| 67 | MP0006082_CNS_inflammation | 1.02612202 |
| 68 | MP0000716_abnormal_immune_system | 1.02448839 |
| 69 | MP0006276_abnormal_autonomic_nervous | 1.01413927 |
| 70 | MP0003186_abnormal_redox_activity | 1.00695002 |
| 71 | MP0004043_abnormal_pH_regulation | 0.99629394 |
| 72 | MP0002398_abnormal_bone_marrow | 0.99332867 |
| 73 | MP0008995_early_reproductive_senescence | 0.99106042 |
| 74 | MP0003283_abnormal_digestive_organ | 0.99097508 |
| 75 | MP0005410_abnormal_fertilization | 0.98206685 |
| 76 | MP0003252_abnormal_bile_duct | 0.95987978 |
| 77 | MP0000689_abnormal_spleen_morphology | 0.95356903 |
| 78 | MP0005174_abnormal_tail_pigmentation | 0.94961831 |
| 79 | MP0001501_abnormal_sleep_pattern | 0.94426773 |
| 80 | MP0005360_urolithiasis | 0.94355341 |
| 81 | MP0003724_increased_susceptibility_to | 0.93897391 |
| 82 | MP0009745_abnormal_behavioral_response | 0.93332551 |
| 83 | MP0005332_abnormal_amino_acid | 0.92453470 |
| 84 | MP0010386_abnormal_urinary_bladder | 0.92162405 |
| 85 | MP0002234_abnormal_pharynx_morphology | 0.87582257 |
| 86 | MP0003880_abnormal_central_pattern | 0.86512309 |
| 87 | MP0008469_abnormal_protein_level | 0.85838934 |
| 88 | MP0001984_abnormal_olfaction | 0.85718373 |
| 89 | MP0003806_abnormal_nucleotide_metabolis | 0.84498988 |
| 90 | MP0002405_respiratory_system_inflammati | 0.83724817 |
| 91 | MP0000703_abnormal_thymus_morphology | 0.81858024 |
| 92 | MP0002272_abnormal_nervous_system | 0.81246624 |
| 93 | MP0001765_abnormal_ion_homeostasis | 0.80771307 |
| 94 | MP0000230_abnormal_systemic_arterial | 0.79410096 |
| 95 | MP0005085_abnormal_gallbladder_physiolo | 0.78417223 |
| 96 | MP0002429_abnormal_blood_cell | 0.78352461 |
| 97 | MP0002722_abnormal_immune_system | 0.78290179 |
| 98 | MP0001485_abnormal_pinna_reflex | 0.77339908 |
| 99 | MP0009643_abnormal_urine_homeostasis | 0.77227239 |
| 100 | MP0005377_hearing/vestibular/ear_phenot | 0.76769627 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.22230879 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 4.00355853 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 3.97256785 |
| 4 | Increased CSF lactate (HP:0002490) | 3.85980121 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 3.72222026 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.69602594 |
| 7 | IgG deficiency (HP:0004315) | 3.69343423 |
| 8 | Hepatocellular necrosis (HP:0001404) | 3.64251069 |
| 9 | 3-Methylglutaconic aciduria (HP:0003535) | 3.58868910 |
| 10 | Renal Fanconi syndrome (HP:0001994) | 3.51559934 |
| 11 | Increased intramyocellular lipid droplets (HP:0012240) | 3.47676881 |
| 12 | Progressive macrocephaly (HP:0004481) | 3.47508220 |
| 13 | Acute encephalopathy (HP:0006846) | 3.36419923 |
| 14 | Aplastic anemia (HP:0001915) | 3.34977226 |
| 15 | Hepatic necrosis (HP:0002605) | 3.34765049 |
| 16 | Congenital stationary night blindness (HP:0007642) | 3.30809775 |
| 17 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.10389272 |
| 18 | Hypoproteinemia (HP:0003075) | 2.99911531 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.99193311 |
| 20 | Methylmalonic acidemia (HP:0002912) | 2.98716653 |
| 21 | Pancreatic cysts (HP:0001737) | 2.96086732 |
| 22 | Increased muscle lipid content (HP:0009058) | 2.90564618 |
| 23 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.90147468 |
| 24 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.90147468 |
| 25 | Severe combined immunodeficiency (HP:0004430) | 2.87286932 |
| 26 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.78648101 |
| 27 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.75470688 |
| 28 | Increased serum lactate (HP:0002151) | 2.72620350 |
| 29 | Exertional dyspnea (HP:0002875) | 2.72301929 |
| 30 | Stomatitis (HP:0010280) | 2.69873330 |
| 31 | Cerebral edema (HP:0002181) | 2.66577239 |
| 32 | Thyroiditis (HP:0100646) | 2.66200688 |
| 33 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.62226223 |
| 34 | Methylmalonic aciduria (HP:0012120) | 2.62192073 |
| 35 | Abolished electroretinogram (ERG) (HP:0000550) | 2.61731307 |
| 36 | Attenuation of retinal blood vessels (HP:0007843) | 2.54399039 |
| 37 | Decreased central vision (HP:0007663) | 2.52801261 |
| 38 | Lactic acidosis (HP:0003128) | 2.52591829 |
| 39 | Abnormality of midbrain morphology (HP:0002418) | 2.50446426 |
| 40 | Molar tooth sign on MRI (HP:0002419) | 2.50446426 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.48631572 |
| 42 | Abnormality of B cell number (HP:0010975) | 2.47453365 |
| 43 | True hermaphroditism (HP:0010459) | 2.45295609 |
| 44 | Optic disc pallor (HP:0000543) | 2.37996003 |
| 45 | B lymphocytopenia (HP:0010976) | 2.36746069 |
| 46 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.33664929 |
| 47 | T lymphocytopenia (HP:0005403) | 2.29900480 |
| 48 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.26063844 |
| 49 | Abnormality of T cell number (HP:0011839) | 2.25065923 |
| 50 | Glycosuria (HP:0003076) | 2.23980157 |
| 51 | Abnormality of urine glucose concentration (HP:0011016) | 2.23980157 |
| 52 | Type II lissencephaly (HP:0007260) | 2.23587320 |
| 53 | Abnormality of renal resorption (HP:0011038) | 2.21527341 |
| 54 | Abnormality of T cells (HP:0002843) | 2.19803403 |
| 55 | Ketoacidosis (HP:0001993) | 2.19331823 |
| 56 | Ketosis (HP:0001946) | 2.18621813 |
| 57 | Abnormality of the renal cortex (HP:0011035) | 2.18454521 |
| 58 | Lethargy (HP:0001254) | 2.17209738 |
| 59 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.16667998 |
| 60 | Dicarboxylic aciduria (HP:0003215) | 2.16667998 |
| 61 | Autoimmune hemolytic anemia (HP:0001890) | 2.13371082 |
| 62 | Respiratory failure (HP:0002878) | 2.10930892 |
| 63 | Nephronophthisis (HP:0000090) | 2.10907554 |
| 64 | Congenital, generalized hypertrichosis (HP:0004540) | 2.10626596 |
| 65 | Respiratory difficulties (HP:0002880) | 2.09612462 |
| 66 | Renal cortical cysts (HP:0000803) | 2.09410857 |
| 67 | Hypothermia (HP:0002045) | 2.05721690 |
| 68 | Combined immunodeficiency (HP:0005387) | 2.03880786 |
| 69 | Pendular nystagmus (HP:0012043) | 2.02854358 |
| 70 | Abnormality of vitamin B metabolism (HP:0004340) | 2.02593744 |
| 71 | Macrocytic anemia (HP:0001972) | 2.01792177 |
| 72 | Abnormality of eosinophils (HP:0001879) | 1.98979220 |
| 73 | Abnormality of the prostate (HP:0008775) | 1.98782894 |
| 74 | Panhypogammaglobulinemia (HP:0003139) | 1.98517740 |
| 75 | Abnormal number of erythroid precursors (HP:0012131) | 1.98108616 |
| 76 | Abnormality of cells of the erythroid lineage (HP:0012130) | 1.97995805 |
| 77 | Absent thumb (HP:0009777) | 1.96790657 |
| 78 | Pancytopenia (HP:0001876) | 1.94900111 |
| 79 | Exercise intolerance (HP:0003546) | 1.94370197 |
| 80 | Abnormality of alanine metabolism (HP:0010916) | 1.93676555 |
| 81 | Hyperalaninemia (HP:0003348) | 1.93676555 |
| 82 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.93676555 |
| 83 | Type 2 muscle fiber atrophy (HP:0003554) | 1.92566217 |
| 84 | Hyperphosphaturia (HP:0003109) | 1.91576655 |
| 85 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 1.87634494 |
| 86 | Increased corneal curvature (HP:0100692) | 1.87032944 |
| 87 | Keratoconus (HP:0000563) | 1.87032944 |
| 88 | Constricted visual fields (HP:0001133) | 1.86222249 |
| 89 | CNS demyelination (HP:0007305) | 1.85214805 |
| 90 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.81694196 |
| 91 | Increased IgM level (HP:0003496) | 1.81636288 |
| 92 | Type I transferrin isoform profile (HP:0003642) | 1.78756023 |
| 93 | Hypoplasia of the uterus (HP:0000013) | 1.77908326 |
| 94 | Polydipsia (HP:0001959) | 1.75970581 |
| 95 | Abnormal drinking behavior (HP:0030082) | 1.75970581 |
| 96 | IgM deficiency (HP:0002850) | 1.75008262 |
| 97 | Hyperglycinemia (HP:0002154) | 1.74777894 |
| 98 | Abnormality of the renal medulla (HP:0100957) | 1.71517293 |
| 99 | Abnormality of T cell physiology (HP:0011840) | 1.70563083 |
| 100 | Eosinophilia (HP:0001880) | 1.68914572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.19900440 |
| 2 | FRK | 3.08892950 |
| 3 | KDR | 2.88052149 |
| 4 | ZAK | 2.77930462 |
| 5 | ADRBK2 | 2.66920860 |
| 6 | MAP4K2 | 2.64827954 |
| 7 | TAOK3 | 2.61040346 |
| 8 | TLK1 | 2.58388345 |
| 9 | VRK2 | 2.53392688 |
| 10 | NUAK1 | 2.38227923 |
| 11 | BCKDK | 2.33374889 |
| 12 | GRK1 | 2.30996880 |
| 13 | TESK2 | 1.99175994 |
| 14 | MAP4K1 | 1.88088213 |
| 15 | ITK | 1.79773493 |
| 16 | VRK1 | 1.75508336 |
| 17 | STK16 | 1.75359331 |
| 18 | BMPR1B | 1.65011706 |
| 19 | FES | 1.55295128 |
| 20 | MST4 | 1.54574320 |
| 21 | TEC | 1.42474868 |
| 22 | WNK4 | 1.38743076 |
| 23 | PINK1 | 1.38037899 |
| 24 | CDK19 | 1.36479161 |
| 25 | WNK3 | 1.30819769 |
| 26 | PASK | 1.30135504 |
| 27 | MAP2K6 | 1.26859867 |
| 28 | EIF2AK3 | 1.26718976 |
| 29 | IKBKB | 1.20004382 |
| 30 | MAP3K12 | 1.19948110 |
| 31 | TIE1 | 1.19154299 |
| 32 | GRK6 | 1.19050771 |
| 33 | SYK | 1.14599619 |
| 34 | SCYL2 | 1.14160766 |
| 35 | OXSR1 | 1.09726866 |
| 36 | KIT | 1.09032595 |
| 37 | IKBKE | 1.09018984 |
| 38 | LIMK1 | 1.06623660 |
| 39 | PRKCQ | 1.00945617 |
| 40 | INSRR | 1.00548824 |
| 41 | LCK | 0.95839797 |
| 42 | BUB1 | 0.91864194 |
| 43 | MUSK | 0.90078502 |
| 44 | PHKG2 | 0.89325378 |
| 45 | PHKG1 | 0.89325378 |
| 46 | ADRBK1 | 0.85957313 |
| 47 | NME1 | 0.84535138 |
| 48 | ACVR1B | 0.82802680 |
| 49 | CSNK1G3 | 0.82602633 |
| 50 | TNK2 | 0.81152282 |
| 51 | BMPR2 | 0.79454498 |
| 52 | DAPK1 | 0.77090123 |
| 53 | RPS6KA5 | 0.76705928 |
| 54 | CSNK1G1 | 0.76184208 |
| 55 | BTK | 0.73681659 |
| 56 | TRIM28 | 0.73087429 |
| 57 | LYN | 0.72354885 |
| 58 | STK39 | 0.71070928 |
| 59 | GRK7 | 0.71008582 |
| 60 | CSF1R | 0.70138517 |
| 61 | CAMKK2 | 0.69738535 |
| 62 | CSNK1G2 | 0.69244278 |
| 63 | MYLK | 0.68490830 |
| 64 | PIK3CG | 0.64603405 |
| 65 | DYRK2 | 0.63642649 |
| 66 | MAPK13 | 0.63200132 |
| 67 | OBSCN | 0.61797138 |
| 68 | PLK3 | 0.61469532 |
| 69 | TBK1 | 0.60153417 |
| 70 | DAPK2 | 0.59762707 |
| 71 | PRKCE | 0.59476284 |
| 72 | JAK3 | 0.58310271 |
| 73 | PIM1 | 0.56868148 |
| 74 | ERBB3 | 0.56492024 |
| 75 | PIK3CA | 0.54211032 |
| 76 | PLK2 | 0.52575202 |
| 77 | PRKCG | 0.51208898 |
| 78 | TAF1 | 0.49969619 |
| 79 | PRKCA | 0.49870050 |
| 80 | GRK5 | 0.49097656 |
| 81 | MAPKAPK3 | 0.48120773 |
| 82 | FLT3 | 0.45827270 |
| 83 | PRKACA | 0.45583096 |
| 84 | ZAP70 | 0.45287036 |
| 85 | IGF1R | 0.45181476 |
| 86 | CDK8 | 0.43777282 |
| 87 | CSNK2A2 | 0.41741488 |
| 88 | CSNK2A1 | 0.39091344 |
| 89 | CSNK1A1 | 0.38939535 |
| 90 | CSNK1A1L | 0.38254813 |
| 91 | ILK | 0.38024820 |
| 92 | NME2 | 0.37863097 |
| 93 | RPS6KA4 | 0.37395230 |
| 94 | PRKCI | 0.35485489 |
| 95 | PBK | 0.35314426 |
| 96 | MATK | 0.35154241 |
| 97 | CAMK1 | 0.34953885 |
| 98 | MAPKAPK5 | 0.34868647 |
| 99 | DAPK3 | 0.34694856 |
| 100 | TGFBR1 | 0.34651469 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.86281975 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.69265139 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.60651896 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.11454079 |
| 5 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.08338617 |
| 6 | Allograft rejection_Homo sapiens_hsa05330 | 2.40390423 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.39091972 |
| 8 | Asthma_Homo sapiens_hsa05310 | 2.28330026 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.27285681 |
| 10 | Protein export_Homo sapiens_hsa03060 | 2.26946803 |
| 11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.23621646 |
| 12 | RNA polymerase_Homo sapiens_hsa03020 | 2.22503830 |
| 13 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.11266882 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 2.04651900 |
| 15 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.01241722 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.89483699 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79568985 |
| 18 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.71047460 |
| 19 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.65931540 |
| 20 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.63828396 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.59278245 |
| 22 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.58452768 |
| 23 | Phototransduction_Homo sapiens_hsa04744 | 1.57472144 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48692553 |
| 25 | RNA degradation_Homo sapiens_hsa03018 | 1.41247722 |
| 26 | Homologous recombination_Homo sapiens_hsa03440 | 1.36201018 |
| 27 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.35330172 |
| 28 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.32066450 |
| 29 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.30913435 |
| 30 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.27043023 |
| 31 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.25682200 |
| 32 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.24552789 |
| 33 | Peroxisome_Homo sapiens_hsa04146 | 1.22822934 |
| 34 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.22062278 |
| 35 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.19006761 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.16821163 |
| 37 | Basal transcription factors_Homo sapiens_hsa03022 | 1.13513576 |
| 38 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.13019241 |
| 39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.11240972 |
| 40 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.11140799 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.06391541 |
| 42 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.05380330 |
| 43 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.04139030 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97871461 |
| 45 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.96328818 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.94468779 |
| 47 | Purine metabolism_Homo sapiens_hsa00230 | 0.91458177 |
| 48 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.88598851 |
| 49 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.87540092 |
| 50 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.87434348 |
| 51 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.85335644 |
| 52 | Retinol metabolism_Homo sapiens_hsa00830 | 0.81287673 |
| 53 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.80040715 |
| 54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.79313596 |
| 55 | Olfactory transduction_Homo sapiens_hsa04740 | 0.76033960 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.75674753 |
| 57 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.75505838 |
| 58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75195483 |
| 59 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.74354657 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.71272961 |
| 61 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.69332904 |
| 62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.67820891 |
| 63 | Mismatch repair_Homo sapiens_hsa03430 | 0.66834962 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.66744198 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.64582405 |
| 66 | RNA transport_Homo sapiens_hsa03013 | 0.63906608 |
| 67 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.61707677 |
| 68 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.59992390 |
| 69 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58530868 |
| 70 | Spliceosome_Homo sapiens_hsa03040 | 0.58276969 |
| 71 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.57072011 |
| 72 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.56282375 |
| 73 | Sulfur relay system_Homo sapiens_hsa04122 | 0.55957534 |
| 74 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.55102731 |
| 75 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.53774631 |
| 76 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.53431763 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.52356818 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.48623680 |
| 79 | DNA replication_Homo sapiens_hsa03030 | 0.48307158 |
| 80 | Viral myocarditis_Homo sapiens_hsa05416 | 0.46475156 |
| 81 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.46289698 |
| 82 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.46200565 |
| 83 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.45352178 |
| 84 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.44864463 |
| 85 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.41627224 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.41321789 |
| 87 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.40583665 |
| 88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.40256222 |
| 89 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.35642201 |
| 90 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.33808743 |
| 91 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31758149 |
| 92 | Measles_Homo sapiens_hsa05162 | 0.30919127 |
| 93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.30868264 |
| 94 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.29192401 |
| 95 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.29037778 |
| 96 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.28360474 |
| 97 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.27290782 |
| 98 | ABC transporters_Homo sapiens_hsa02010 | 0.26512300 |
| 99 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.25738644 |
| 100 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.23975438 |

