

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 5.37300926 |
| 2 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 5.36560124 |
| 3 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 5.36560124 |
| 4 | ribosomal small subunit assembly (GO:0000028) | 5.31217006 |
| 5 | translational termination (GO:0006415) | 5.26037592 |
| 6 | DNA deamination (GO:0045006) | 4.84946983 |
| 7 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.70488509 |
| 8 | translational elongation (GO:0006414) | 4.67073527 |
| 9 | cotranslational protein targeting to membrane (GO:0006613) | 4.64339983 |
| 10 | protein targeting to ER (GO:0045047) | 4.61241013 |
| 11 | behavioral response to nicotine (GO:0035095) | 4.58094889 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.53516048 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.53516048 |
| 14 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.41065249 |
| 15 | ribosomal small subunit biogenesis (GO:0042274) | 4.37112830 |
| 16 | protein localization to endoplasmic reticulum (GO:0070972) | 4.32795240 |
| 17 | protein complex biogenesis (GO:0070271) | 4.26330649 |
| 18 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.18759815 |
| 19 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.13228941 |
| 20 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.03365705 |
| 21 | fucose catabolic process (GO:0019317) | 3.94727811 |
| 22 | L-fucose metabolic process (GO:0042354) | 3.94727811 |
| 23 | L-fucose catabolic process (GO:0042355) | 3.94727811 |
| 24 | CTP biosynthetic process (GO:0006241) | 3.92045304 |
| 25 | CTP metabolic process (GO:0046036) | 3.92045304 |
| 26 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.87907773 |
| 27 | cellular protein complex disassembly (GO:0043624) | 3.85325160 |
| 28 | viral life cycle (GO:0019058) | 3.84711318 |
| 29 | regulation of memory T cell differentiation (GO:0043380) | 3.82079021 |
| 30 | chaperone-mediated protein transport (GO:0072321) | 3.73252294 |
| 31 | regulation of activation of Janus kinase activity (GO:0010533) | 3.68576213 |
| 32 | translational initiation (GO:0006413) | 3.67582162 |
| 33 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.63921133 |
| 34 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.62384585 |
| 35 | maturation of SSU-rRNA (GO:0030490) | 3.57684763 |
| 36 | translation (GO:0006412) | 3.55337000 |
| 37 | DNA double-strand break processing (GO:0000729) | 3.53903622 |
| 38 | ribosomal large subunit biogenesis (GO:0042273) | 3.53063657 |
| 39 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.51785473 |
| 40 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.50925915 |
| 41 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.47523162 |
| 42 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.45148178 |
| 43 | cytochrome complex assembly (GO:0017004) | 3.44848527 |
| 44 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.36707261 |
| 45 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.33397915 |
| 46 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.30468949 |
| 47 | rRNA modification (GO:0000154) | 3.26595730 |
| 48 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.26093612 |
| 49 | NADH dehydrogenase complex assembly (GO:0010257) | 3.26093612 |
| 50 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.26093612 |
| 51 | GTP biosynthetic process (GO:0006183) | 3.25875092 |
| 52 | pseudouridine synthesis (GO:0001522) | 3.25457588 |
| 53 | nucleotide salvage (GO:0043173) | 3.22032779 |
| 54 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.21110726 |
| 55 | respiratory chain complex IV assembly (GO:0008535) | 3.19169285 |
| 56 | protein complex disassembly (GO:0043241) | 3.17326057 |
| 57 | electron transport chain (GO:0022900) | 3.16970505 |
| 58 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.16175627 |
| 59 | tRNA processing (GO:0008033) | 3.12939158 |
| 60 | respiratory electron transport chain (GO:0022904) | 3.10841425 |
| 61 | positive regulation of cell fate commitment (GO:0010455) | 3.10448624 |
| 62 | protein neddylation (GO:0045116) | 3.10064125 |
| 63 | nucleoside salvage (GO:0043174) | 3.05652985 |
| 64 | macromolecular complex disassembly (GO:0032984) | 3.00050684 |
| 65 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.95970364 |
| 66 | cellular component biogenesis (GO:0044085) | 2.95875942 |
| 67 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 2.95578857 |
| 68 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.94150760 |
| 69 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.92939153 |
| 70 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 2.92891412 |
| 71 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.87913231 |
| 72 | protein targeting to membrane (GO:0006612) | 2.87149170 |
| 73 | signal peptide processing (GO:0006465) | 2.86179382 |
| 74 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.86063616 |
| 75 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 2.85402187 |
| 76 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.84407087 |
| 77 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 2.80853558 |
| 78 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.80363420 |
| 79 | termination of RNA polymerase III transcription (GO:0006386) | 2.80363420 |
| 80 | positive regulation of defense response to virus by host (GO:0002230) | 2.78234134 |
| 81 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 2.77963892 |
| 82 | UMP metabolic process (GO:0046049) | 2.77963892 |
| 83 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 2.77963892 |
| 84 | UMP biosynthetic process (GO:0006222) | 2.77963892 |
| 85 | positive regulation of interleukin-17 production (GO:0032740) | 2.74642129 |
| 86 | UTP biosynthetic process (GO:0006228) | 2.74030569 |
| 87 | rRNA processing (GO:0006364) | 2.73692207 |
| 88 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.71632405 |
| 89 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.71527142 |
| 90 | rRNA methylation (GO:0031167) | 2.71510804 |
| 91 | rRNA metabolic process (GO:0016072) | 2.69600134 |
| 92 | intracellular protein transmembrane import (GO:0044743) | 2.69458043 |
| 93 | piRNA metabolic process (GO:0034587) | 2.69420728 |
| 94 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 2.67812353 |
| 95 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.66756619 |
| 96 | mRNA catabolic process (GO:0006402) | 2.66474343 |
| 97 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.66444570 |
| 98 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 2.65818015 |
| 99 | mannosylation (GO:0097502) | 2.64040853 |
| 100 | L-methionine biosynthetic process (GO:0071265) | 2.62800690 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.99877225 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.91176424 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.48864131 |
| 4 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.34978345 |
| 5 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.94378078 |
| 6 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.74759677 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.74530149 |
| 8 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.61737709 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.59515488 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.59325327 |
| 11 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.46517184 |
| 12 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.41100877 |
| 13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.30376464 |
| 14 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.27451116 |
| 15 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.26926801 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.17033561 |
| 17 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.13881770 |
| 18 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.09476330 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.99212825 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.97879390 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.95130601 |
| 22 | EWS_26573619_Chip-Seq_HEK293_Human | 1.94481489 |
| 23 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.90920884 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.87735332 |
| 25 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81578266 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.75069217 |
| 27 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.71425672 |
| 28 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.70049337 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.65050797 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.55149215 |
| 31 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.48588072 |
| 32 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.46417494 |
| 33 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.45995488 |
| 34 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.45947492 |
| 35 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.45764226 |
| 36 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.45096773 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44347310 |
| 38 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.43104904 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.41609155 |
| 40 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34267247 |
| 41 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34267247 |
| 42 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34141325 |
| 43 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.32623722 |
| 44 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.32623722 |
| 45 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.31793601 |
| 46 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.31736534 |
| 47 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.30846975 |
| 48 | P300_19829295_ChIP-Seq_ESCs_Human | 1.29574234 |
| 49 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.26935549 |
| 50 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.25670370 |
| 51 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21844043 |
| 52 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.20562764 |
| 53 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.18042816 |
| 54 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.16769146 |
| 55 | AR_20517297_ChIP-Seq_VCAP_Human | 1.15529282 |
| 56 | NCOR_22424771_ChIP-Seq_293T_Human | 1.15337249 |
| 57 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14959955 |
| 58 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.14747253 |
| 59 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11564062 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11092693 |
| 61 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09931441 |
| 62 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.09648535 |
| 63 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.07523365 |
| 64 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.07523365 |
| 65 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.06636409 |
| 66 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.06288964 |
| 67 | GATA3_26560356_Chip-Seq_TH2_Human | 1.05917437 |
| 68 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.05215666 |
| 69 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.04913157 |
| 70 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.04205385 |
| 71 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.04032826 |
| 72 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.03387081 |
| 73 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.03008044 |
| 74 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.02316251 |
| 75 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.01821912 |
| 76 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.01713746 |
| 77 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.01617745 |
| 78 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.00059117 |
| 79 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.99796814 |
| 80 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99757718 |
| 81 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.99689440 |
| 82 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.99621042 |
| 83 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.99262585 |
| 84 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.98619889 |
| 85 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.98326421 |
| 86 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.98251271 |
| 87 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.96733689 |
| 88 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.96075615 |
| 89 | ERA_21632823_ChIP-Seq_H3396_Human | 0.95014586 |
| 90 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.93011204 |
| 91 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.92675350 |
| 92 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.91681231 |
| 93 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.91231747 |
| 94 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.90526038 |
| 95 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.89472603 |
| 96 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.88905360 |
| 97 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.88514911 |
| 98 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.88339072 |
| 99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.88038335 |
| 100 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.87332237 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 3.45590255 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.27867247 |
| 3 | MP0008875_abnormal_xenobiotic_pharmacok | 2.99556813 |
| 4 | MP0005360_urolithiasis | 2.77886649 |
| 5 | MP0004885_abnormal_endolymph | 2.57691779 |
| 6 | MP0006072_abnormal_retinal_apoptosis | 2.55439164 |
| 7 | MP0003646_muscle_fatigue | 2.53296918 |
| 8 | MP0008872_abnormal_physiological_respon | 2.36703902 |
| 9 | MP0008877_abnormal_DNA_methylation | 2.34786491 |
| 10 | MP0002102_abnormal_ear_morphology | 2.27008745 |
| 11 | MP0002837_dystrophic_cardiac_calcinosis | 2.24217431 |
| 12 | MP0002163_abnormal_gland_morphology | 2.22725121 |
| 13 | MP0002638_abnormal_pupillary_reflex | 2.13300628 |
| 14 | MP0001986_abnormal_taste_sensitivity | 2.03441196 |
| 15 | MP0003787_abnormal_imprinting | 2.01265779 |
| 16 | MP0002876_abnormal_thyroid_physiology | 1.93572015 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.90422440 |
| 18 | MP0004142_abnormal_muscle_tone | 1.90253958 |
| 19 | MP0001968_abnormal_touch/_nociception | 1.88564552 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.83090314 |
| 21 | MP0003195_calcinosis | 1.81022185 |
| 22 | MP0005645_abnormal_hypothalamus_physiol | 1.77473789 |
| 23 | MP0002736_abnormal_nociception_after | 1.74708738 |
| 24 | MP0002138_abnormal_hepatobiliary_system | 1.64547615 |
| 25 | MP0005379_endocrine/exocrine_gland_phen | 1.64507378 |
| 26 | MP0004147_increased_porphyrin_level | 1.63866111 |
| 27 | MP0003718_maternal_effect | 1.56935408 |
| 28 | MP0005671_abnormal_response_to | 1.55642918 |
| 29 | MP0005389_reproductive_system_phenotype | 1.53924958 |
| 30 | MP0001501_abnormal_sleep_pattern | 1.52620355 |
| 31 | MP0001984_abnormal_olfaction | 1.51642232 |
| 32 | MP0002277_abnormal_respiratory_mucosa | 1.42667565 |
| 33 | MP0001905_abnormal_dopamine_level | 1.42082696 |
| 34 | MP0010386_abnormal_urinary_bladder | 1.39574407 |
| 35 | MP0008058_abnormal_DNA_repair | 1.39544511 |
| 36 | MP0003011_delayed_dark_adaptation | 1.38375177 |
| 37 | MP0009046_muscle_twitch | 1.36537967 |
| 38 | MP0002160_abnormal_reproductive_system | 1.35036069 |
| 39 | MP0000372_irregular_coat_pigmentation | 1.33687320 |
| 40 | MP0006276_abnormal_autonomic_nervous | 1.32367188 |
| 41 | MP0009785_altered_susceptibility_to | 1.29402188 |
| 42 | MP0005075_abnormal_melanosome_morpholog | 1.28426995 |
| 43 | MP0009745_abnormal_behavioral_response | 1.27411921 |
| 44 | MP0002272_abnormal_nervous_system | 1.26727868 |
| 45 | MP0005253_abnormal_eye_physiology | 1.25838489 |
| 46 | MP0002234_abnormal_pharynx_morphology | 1.24781979 |
| 47 | MP0001835_abnormal_antigen_presentation | 1.24459364 |
| 48 | MP0005387_immune_system_phenotype | 1.19719240 |
| 49 | MP0001790_abnormal_immune_system | 1.19719240 |
| 50 | MP0001919_abnormal_reproductive_system | 1.18867449 |
| 51 | MP0003121_genomic_imprinting | 1.16847972 |
| 52 | MP0005332_abnormal_amino_acid | 1.16355160 |
| 53 | MP0000631_abnormal_neuroendocrine_gland | 1.15082664 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.14570148 |
| 55 | MP0003283_abnormal_digestive_organ | 1.13728618 |
| 56 | MP0005636_abnormal_mineral_homeostasis | 1.10545382 |
| 57 | MP0003567_abnormal_fetal_cardiomyocyte | 1.09069990 |
| 58 | MP0005646_abnormal_pituitary_gland | 1.08871318 |
| 59 | MP0002148_abnormal_hypersensitivity_rea | 1.08344864 |
| 60 | MP0002938_white_spotting | 1.08238560 |
| 61 | MP0003122_maternal_imprinting | 1.05257207 |
| 62 | MP0006036_abnormal_mitochondrial_physio | 1.05044287 |
| 63 | MP0000538_abnormal_urinary_bladder | 1.04386303 |
| 64 | MP0002095_abnormal_skin_pigmentation | 1.03325012 |
| 65 | MP0002909_abnormal_adrenal_gland | 0.99205128 |
| 66 | MP0003786_premature_aging | 0.98411733 |
| 67 | MP0008789_abnormal_olfactory_epithelium | 0.97910138 |
| 68 | MP0001873_stomach_inflammation | 0.95697034 |
| 69 | MP0001756_abnormal_urination | 0.95252125 |
| 70 | MP0003186_abnormal_redox_activity | 0.93787310 |
| 71 | MP0001485_abnormal_pinna_reflex | 0.92590648 |
| 72 | MP0003252_abnormal_bile_duct | 0.91099457 |
| 73 | MP0008775_abnormal_heart_ventricle | 0.89535114 |
| 74 | MP0005000_abnormal_immune_tolerance | 0.89252634 |
| 75 | MP0001800_abnormal_humoral_immune | 0.89182371 |
| 76 | MP0004019_abnormal_vitamin_homeostasis | 0.87862881 |
| 77 | MP0002693_abnormal_pancreas_physiology | 0.87068741 |
| 78 | MP0001293_anophthalmia | 0.87043015 |
| 79 | MP0003880_abnormal_central_pattern | 0.86452448 |
| 80 | MP0001970_abnormal_pain_threshold | 0.84916426 |
| 81 | MP0005085_abnormal_gallbladder_physiolo | 0.84252823 |
| 82 | MP0000427_abnormal_hair_cycle | 0.83115611 |
| 83 | MP0004133_heterotaxia | 0.79457812 |
| 84 | MP0010329_abnormal_lipoprotein_level | 0.78775031 |
| 85 | MP0001944_abnormal_pancreas_morphology | 0.78233735 |
| 86 | MP0004043_abnormal_pH_regulation | 0.77913361 |
| 87 | MP0005167_abnormal_blood-brain_barrier | 0.77546425 |
| 88 | MP0003638_abnormal_response/metabolism_ | 0.76982832 |
| 89 | MP0001765_abnormal_ion_homeostasis | 0.76570123 |
| 90 | MP0004742_abnormal_vestibular_system | 0.76486290 |
| 91 | MP0000685_abnormal_immune_system | 0.74584907 |
| 92 | MP0000230_abnormal_systemic_arterial | 0.74256682 |
| 93 | MP0009643_abnormal_urine_homeostasis | 0.74015703 |
| 94 | MP0005195_abnormal_posterior_eye | 0.71661349 |
| 95 | MP0002733_abnormal_thermal_nociception | 0.71085648 |
| 96 | MP0001502_abnormal_circadian_rhythm | 0.70224611 |
| 97 | MP0002006_tumorigenesis | 0.70110505 |
| 98 | MP0005410_abnormal_fertilization | 0.70074214 |
| 99 | MP0002229_neurodegeneration | 0.69097421 |
| 100 | MP0002735_abnormal_chemical_nociception | 0.68585656 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.98716352 |
| 2 | Increased hepatocellular lipid droplets (HP:0006565) | 3.88871725 |
| 3 | Lipid accumulation in hepatocytes (HP:0006561) | 3.71687290 |
| 4 | Pancreatic fibrosis (HP:0100732) | 3.66905636 |
| 5 | Pancreatic cysts (HP:0001737) | 3.66457086 |
| 6 | Mitochondrial inheritance (HP:0001427) | 3.56859933 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.46936365 |
| 8 | Progressive macrocephaly (HP:0004481) | 3.43029118 |
| 9 | Acute encephalopathy (HP:0006846) | 3.40666829 |
| 10 | Increased CSF lactate (HP:0002490) | 3.25937988 |
| 11 | Abnormality of midbrain morphology (HP:0002418) | 3.23499196 |
| 12 | Molar tooth sign on MRI (HP:0002419) | 3.23499196 |
| 13 | Congenital stationary night blindness (HP:0007642) | 3.21836211 |
| 14 | Renal Fanconi syndrome (HP:0001994) | 3.14719814 |
| 15 | IgG deficiency (HP:0004315) | 3.06307241 |
| 16 | Nephronophthisis (HP:0000090) | 2.97420451 |
| 17 | Abnormal biliary tract physiology (HP:0012439) | 2.97077065 |
| 18 | Bile duct proliferation (HP:0001408) | 2.97077065 |
| 19 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.96058324 |
| 20 | Congenital, generalized hypertrichosis (HP:0004540) | 2.85852905 |
| 21 | Hypoplasia of the pons (HP:0012110) | 2.85422694 |
| 22 | Abnormality of the renal cortex (HP:0011035) | 2.82715943 |
| 23 | True hermaphroditism (HP:0010459) | 2.80109585 |
| 24 | Reticulocytopenia (HP:0001896) | 2.77667960 |
| 25 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.77301900 |
| 26 | Abnormality of the pons (HP:0007361) | 2.75801291 |
| 27 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.74298154 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.71452629 |
| 29 | Stomatitis (HP:0010280) | 2.68180289 |
| 30 | Abnormal drinking behavior (HP:0030082) | 2.67184298 |
| 31 | Polydipsia (HP:0001959) | 2.67184298 |
| 32 | Asplenia (HP:0001746) | 2.63871688 |
| 33 | Exertional dyspnea (HP:0002875) | 2.62988290 |
| 34 | Hepatic necrosis (HP:0002605) | 2.62797018 |
| 35 | Hepatocellular necrosis (HP:0001404) | 2.62172184 |
| 36 | Pendular nystagmus (HP:0012043) | 2.58285992 |
| 37 | Abnormality of the renal medulla (HP:0100957) | 2.56765713 |
| 38 | Cerebral edema (HP:0002181) | 2.52692654 |
| 39 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.50857685 |
| 40 | Increased intramyocellular lipid droplets (HP:0012240) | 2.50436140 |
| 41 | Abnormal number of erythroid precursors (HP:0012131) | 2.48640473 |
| 42 | Methylmalonic acidemia (HP:0002912) | 2.47548977 |
| 43 | Macrocytic anemia (HP:0001972) | 2.46347527 |
| 44 | Medial flaring of the eyebrow (HP:0010747) | 2.42072265 |
| 45 | Tubular atrophy (HP:0000092) | 2.32613253 |
| 46 | Hyperglycinemia (HP:0002154) | 2.32050506 |
| 47 | Parakeratosis (HP:0001036) | 2.30305739 |
| 48 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.28434158 |
| 49 | Erythroderma (HP:0001019) | 2.25621752 |
| 50 | Polyuria (HP:0000103) | 2.24653625 |
| 51 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.24418407 |
| 52 | 3-Methylglutaconic aciduria (HP:0003535) | 2.23899782 |
| 53 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.22064435 |
| 54 | Abnormality of renal resorption (HP:0011038) | 2.21759338 |
| 55 | Optic disc pallor (HP:0000543) | 2.19840592 |
| 56 | Abolished electroretinogram (ERG) (HP:0000550) | 2.18983541 |
| 57 | Cystic liver disease (HP:0006706) | 2.17875034 |
| 58 | Glycosuria (HP:0003076) | 2.17710927 |
| 59 | Abnormality of urine glucose concentration (HP:0011016) | 2.17710927 |
| 60 | Increased muscle lipid content (HP:0009058) | 2.13384022 |
| 61 | Panhypogammaglobulinemia (HP:0003139) | 2.12549488 |
| 62 | Poor suck (HP:0002033) | 2.10688252 |
| 63 | Increased serum lactate (HP:0002151) | 2.08686993 |
| 64 | Renal cortical cysts (HP:0000803) | 2.07266434 |
| 65 | Supernumerary spleens (HP:0009799) | 2.07123871 |
| 66 | Type II lissencephaly (HP:0007260) | 2.06567036 |
| 67 | Hypomagnesemia (HP:0002917) | 2.06497174 |
| 68 | Pallor (HP:0000980) | 2.04278889 |
| 69 | Methylmalonic aciduria (HP:0012120) | 2.04048880 |
| 70 | Decreased central vision (HP:0007663) | 2.02323470 |
| 71 | Attenuation of retinal blood vessels (HP:0007843) | 2.01103725 |
| 72 | Absent thumb (HP:0009777) | 1.97691374 |
| 73 | Opisthotonus (HP:0002179) | 1.97042444 |
| 74 | Keratoconus (HP:0000563) | 1.91071740 |
| 75 | Increased corneal curvature (HP:0100692) | 1.91071740 |
| 76 | Lactic acidosis (HP:0003128) | 1.90494252 |
| 77 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.89806244 |
| 78 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.89806244 |
| 79 | Lethargy (HP:0001254) | 1.87467971 |
| 80 | Hypoplasia of the uterus (HP:0000013) | 1.87174328 |
| 81 | Sclerocornea (HP:0000647) | 1.85921468 |
| 82 | Respiratory failure (HP:0002878) | 1.82502941 |
| 83 | B lymphocytopenia (HP:0010976) | 1.81905133 |
| 84 | Abnormal urine output (HP:0012590) | 1.81553206 |
| 85 | Abnormality of B cell number (HP:0010975) | 1.81483265 |
| 86 | Anencephaly (HP:0002323) | 1.81476305 |
| 87 | Thyroiditis (HP:0100646) | 1.80426045 |
| 88 | Adrenal hypoplasia (HP:0000835) | 1.80399780 |
| 89 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.80303172 |
| 90 | Abnormality of alanine metabolism (HP:0010916) | 1.80303172 |
| 91 | Hyperalaninemia (HP:0003348) | 1.80303172 |
| 92 | Large for gestational age (HP:0001520) | 1.79925248 |
| 93 | Degeneration of anterior horn cells (HP:0002398) | 1.79821343 |
| 94 | Abnormality of the anterior horn cell (HP:0006802) | 1.79821343 |
| 95 | Hyperphosphaturia (HP:0003109) | 1.79197083 |
| 96 | Hyperinsulinemic hypoglycemia (HP:0000825) | 1.76010659 |
| 97 | Leukodystrophy (HP:0002415) | 1.75499514 |
| 98 | Dyskinesia (HP:0100660) | 1.73882079 |
| 99 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.72484367 |
| 100 | Gait imbalance (HP:0002141) | 1.72324227 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ADRBK2 | 3.36596774 |
| 2 | FRK | 3.27643666 |
| 3 | GRK1 | 2.87929797 |
| 4 | BMPR1B | 2.87609096 |
| 5 | VRK2 | 2.79815072 |
| 6 | TAOK3 | 2.61113268 |
| 7 | ZAK | 2.52577881 |
| 8 | NUAK1 | 2.51969263 |
| 9 | TXK | 2.51843719 |
| 10 | WNK4 | 2.50983610 |
| 11 | STK16 | 2.47865161 |
| 12 | TLK1 | 2.46208643 |
| 13 | MAP4K2 | 2.06790712 |
| 14 | MST4 | 1.99658661 |
| 15 | TIE1 | 1.94373238 |
| 16 | MAP4K1 | 1.67676824 |
| 17 | TAF1 | 1.67345351 |
| 18 | PASK | 1.65957637 |
| 19 | STK39 | 1.57040285 |
| 20 | PHKG1 | 1.56813140 |
| 21 | PHKG2 | 1.56813140 |
| 22 | VRK1 | 1.55077866 |
| 23 | WNK3 | 1.44938636 |
| 24 | OXSR1 | 1.44433585 |
| 25 | BCKDK | 1.35021507 |
| 26 | PLK2 | 1.34698192 |
| 27 | PLK3 | 1.33256884 |
| 28 | ITK | 1.30021145 |
| 29 | NME1 | 1.28298110 |
| 30 | TEC | 1.28014161 |
| 31 | TNIK | 1.20566643 |
| 32 | NME2 | 1.19007803 |
| 33 | LIMK1 | 1.18095123 |
| 34 | MAP2K6 | 1.15998598 |
| 35 | EIF2AK3 | 1.15893644 |
| 36 | PRKCG | 1.14871400 |
| 37 | PINK1 | 1.14856117 |
| 38 | EIF2AK1 | 1.13440124 |
| 39 | DYRK2 | 1.09837912 |
| 40 | NLK | 1.08077465 |
| 41 | TGFBR1 | 1.05554859 |
| 42 | ADRBK1 | 1.05199372 |
| 43 | CDC7 | 1.04684408 |
| 44 | INSRR | 0.97369954 |
| 45 | NEK1 | 0.97304982 |
| 46 | TSSK6 | 0.95103730 |
| 47 | ACVR1B | 0.93411112 |
| 48 | STK3 | 0.89880248 |
| 49 | DAPK2 | 0.86630392 |
| 50 | GRK7 | 0.86393639 |
| 51 | TRIM28 | 0.82869927 |
| 52 | IKBKB | 0.82760396 |
| 53 | CSNK1G1 | 0.82017823 |
| 54 | KIT | 0.79446275 |
| 55 | MAP3K12 | 0.74665405 |
| 56 | PRKCQ | 0.71523498 |
| 57 | MAPKAPK3 | 0.67320156 |
| 58 | PBK | 0.67229341 |
| 59 | MAPKAPK5 | 0.66545443 |
| 60 | BUB1 | 0.65254204 |
| 61 | PRKCE | 0.63576766 |
| 62 | RPS6KA5 | 0.63150638 |
| 63 | CDK19 | 0.63118032 |
| 64 | FGFR2 | 0.62448255 |
| 65 | CSNK2A2 | 0.59152582 |
| 66 | MAP3K9 | 0.58698610 |
| 67 | OBSCN | 0.57915022 |
| 68 | CSNK2A1 | 0.55707765 |
| 69 | IKBKE | 0.54049346 |
| 70 | MKNK2 | 0.52820850 |
| 71 | PLK4 | 0.52034140 |
| 72 | SYK | 0.51348179 |
| 73 | MKNK1 | 0.50630725 |
| 74 | FES | 0.50103946 |
| 75 | PIK3CA | 0.49349649 |
| 76 | PRKACA | 0.47716173 |
| 77 | LCK | 0.47657209 |
| 78 | GRK6 | 0.46284674 |
| 79 | PRKCA | 0.46252231 |
| 80 | PLK1 | 0.44339211 |
| 81 | PIK3CG | 0.43856708 |
| 82 | CSNK1G3 | 0.43526590 |
| 83 | LYN | 0.42709934 |
| 84 | MAPK13 | 0.42277081 |
| 85 | SRPK1 | 0.42067633 |
| 86 | PRKCI | 0.40727105 |
| 87 | GRK5 | 0.39638119 |
| 88 | MAP3K4 | 0.38171214 |
| 89 | MAP3K13 | 0.37871016 |
| 90 | CSNK1A1 | 0.37310058 |
| 91 | STK4 | 0.34564012 |
| 92 | DAPK3 | 0.33879509 |
| 93 | MYLK | 0.33846547 |
| 94 | CSNK1G2 | 0.33721906 |
| 95 | IGF1R | 0.33488745 |
| 96 | CAMK2D | 0.32840286 |
| 97 | EIF2AK2 | 0.32618608 |
| 98 | FLT3 | 0.30812503 |
| 99 | LRRK2 | 0.30294937 |
| 100 | WNK1 | 0.29603587 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.74154683 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.32122313 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 2.72115159 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 2.67456560 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.51817025 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.35441319 |
| 7 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.16087232 |
| 8 | Basal transcription factors_Homo sapiens_hsa03022 | 2.04110409 |
| 9 | Asthma_Homo sapiens_hsa05310 | 2.01735904 |
| 10 | Sulfur relay system_Homo sapiens_hsa04122 | 1.91910905 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.88740101 |
| 12 | RNA degradation_Homo sapiens_hsa03018 | 1.85221354 |
| 13 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.80038122 |
| 14 | Alzheimers disease_Homo sapiens_hsa05010 | 1.69620622 |
| 15 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.68467461 |
| 16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.67418151 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.66478948 |
| 18 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.63973903 |
| 19 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.58120894 |
| 20 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.57453369 |
| 21 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.55970909 |
| 22 | Allograft rejection_Homo sapiens_hsa05330 | 1.55831219 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.55397066 |
| 24 | Phototransduction_Homo sapiens_hsa04744 | 1.54576954 |
| 25 | Homologous recombination_Homo sapiens_hsa03440 | 1.52344157 |
| 26 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.51187419 |
| 27 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.50339576 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.47156793 |
| 29 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.44871985 |
| 30 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.44534526 |
| 31 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.42555673 |
| 32 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.42257221 |
| 33 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.37588665 |
| 34 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.37192297 |
| 35 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.30291362 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.29608851 |
| 37 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.25941866 |
| 38 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.23921119 |
| 39 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.16560366 |
| 40 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15667983 |
| 41 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.15281370 |
| 42 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.11982723 |
| 43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.10782594 |
| 44 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.05602947 |
| 45 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.04558793 |
| 46 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.02943633 |
| 47 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.02861750 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.02285575 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 1.00874109 |
| 50 | Mismatch repair_Homo sapiens_hsa03430 | 0.99708329 |
| 51 | RNA transport_Homo sapiens_hsa03013 | 0.97314845 |
| 52 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.96872820 |
| 53 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.95654165 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.95226374 |
| 55 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.92284458 |
| 56 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.92243396 |
| 57 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.90877201 |
| 58 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.90867275 |
| 59 | DNA replication_Homo sapiens_hsa03030 | 0.90340432 |
| 60 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.90122101 |
| 61 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.85855234 |
| 62 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84493482 |
| 63 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.80694136 |
| 64 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.80288332 |
| 65 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.80229951 |
| 66 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.77915462 |
| 67 | Retinol metabolism_Homo sapiens_hsa00830 | 0.76619522 |
| 68 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.76613600 |
| 69 | Base excision repair_Homo sapiens_hsa03410 | 0.75610407 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75585639 |
| 71 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.72029148 |
| 72 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.71864705 |
| 73 | Spliceosome_Homo sapiens_hsa03040 | 0.68239630 |
| 74 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.67951738 |
| 75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.64198335 |
| 76 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64112884 |
| 77 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.62899130 |
| 78 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.62842370 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.62470859 |
| 80 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.58777468 |
| 81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.57628572 |
| 82 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56346787 |
| 83 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.54771987 |
| 84 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.53402113 |
| 85 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.50660082 |
| 86 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.47702186 |
| 87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.46664700 |
| 88 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.44233110 |
| 89 | Taste transduction_Homo sapiens_hsa04742 | 0.43102784 |
| 90 | Nicotine addiction_Homo sapiens_hsa05033 | 0.42969486 |
| 91 | Morphine addiction_Homo sapiens_hsa05032 | 0.41056490 |
| 92 | Insulin secretion_Homo sapiens_hsa04911 | 0.40830288 |
| 93 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.40067049 |
| 94 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.38646614 |
| 95 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.37421313 |
| 96 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.34593844 |
| 97 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.33962060 |
| 98 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.30643990 |
| 99 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.30493665 |
| 100 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.30152534 |

