

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 9.72864072 |
| 2 | negative regulation of cardiac muscle hypertrophy (GO:0010614) | 9.37306071 |
| 3 | negative regulation of glycogen biosynthetic process (GO:0045719) | 9.12937743 |
| 4 | interleukin-6-mediated signaling pathway (GO:0070102) | 8.98346032 |
| 5 | galactose catabolic process (GO:0019388) | 8.47740883 |
| 6 | negative regulation of muscle hypertrophy (GO:0014741) | 8.47686519 |
| 7 | establishment of skin barrier (GO:0061436) | 8.43181652 |
| 8 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 8.41142287 |
| 9 | tolerance induction (GO:0002507) | 8.38172203 |
| 10 | regulation of oxidative stress-induced neuron death (GO:1903203) | 8.29520942 |
| 11 | membrane tubulation (GO:0097320) | 8.15237670 |
| 12 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 8.05357811 |
| 13 | protein localization to endosome (GO:0036010) | 7.95241335 |
| 14 | N-terminal protein amino acid acetylation (GO:0006474) | 7.85478974 |
| 15 | regulation of energy homeostasis (GO:2000505) | 7.78385750 |
| 16 | negative regulation of glycogen metabolic process (GO:0070874) | 7.33627746 |
| 17 | regulation of water loss via skin (GO:0033561) | 7.07316639 |
| 18 | cellular response to interleukin-6 (GO:0071354) | 6.68468894 |
| 19 | regulation of cellular respiration (GO:0043457) | 6.40710560 |
| 20 | ribosomal small subunit biogenesis (GO:0042274) | 5.68702419 |
| 21 | response to interleukin-6 (GO:0070741) | 5.48546686 |
| 22 | forebrain morphogenesis (GO:0048853) | 5.21483202 |
| 23 | cysteine metabolic process (GO:0006534) | 5.14531852 |
| 24 | viral transcription (GO:0019083) | 5.13676941 |
| 25 | galactose metabolic process (GO:0006012) | 4.88881157 |
| 26 | translational termination (GO:0006415) | 4.86420774 |
| 27 | protein heterotetramerization (GO:0051290) | 4.81975908 |
| 28 | desmosome organization (GO:0002934) | 4.47250267 |
| 29 | multicellular organismal water homeostasis (GO:0050891) | 4.45915748 |
| 30 | ubiquinone biosynthetic process (GO:0006744) | 4.23541675 |
| 31 | response to nitrosative stress (GO:0051409) | 4.19105765 |
| 32 | sequestering of actin monomers (GO:0042989) | 4.13908586 |
| 33 | viral life cycle (GO:0019058) | 4.10357059 |
| 34 | ribonucleoprotein complex biogenesis (GO:0022613) | 4.04965161 |
| 35 | regulation of hypersensitivity (GO:0002883) | 4.03037280 |
| 36 | megakaryocyte development (GO:0035855) | 4.00157607 |
| 37 | spermatid nucleus differentiation (GO:0007289) | 3.96850531 |
| 38 | regulation of the force of heart contraction (GO:0002026) | 3.96663191 |
| 39 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 3.89842444 |
| 40 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.87328167 |
| 41 | keratinocyte proliferation (GO:0043616) | 3.85427219 |
| 42 | water homeostasis (GO:0030104) | 3.84315661 |
| 43 | tyrosine metabolic process (GO:0006570) | 3.84186531 |
| 44 | regulation of natural killer cell differentiation (GO:0032823) | 3.82842686 |
| 45 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 3.81432152 |
| 46 | L-phenylalanine catabolic process (GO:0006559) | 3.81432152 |
| 47 | ribosomal large subunit biogenesis (GO:0042273) | 3.79921071 |
| 48 | cotranslational protein targeting to membrane (GO:0006613) | 3.79635571 |
| 49 | negative regulation of potassium ion transport (GO:0043267) | 3.79538326 |
| 50 | ubiquinone metabolic process (GO:0006743) | 3.77826028 |
| 51 | protein targeting to ER (GO:0045047) | 3.74945031 |
| 52 | regulation of cardiac muscle hypertrophy (GO:0010611) | 3.74185311 |
| 53 | translational elongation (GO:0006414) | 3.69446417 |
| 54 | regulation of chromatin binding (GO:0035561) | 3.69143380 |
| 55 | ribosome biogenesis (GO:0042254) | 3.66102831 |
| 56 | lymph node development (GO:0048535) | 3.64748315 |
| 57 | regulation of muscle hypertrophy (GO:0014743) | 3.61849209 |
| 58 | quinone biosynthetic process (GO:1901663) | 3.58981210 |
| 59 | cellular protein complex disassembly (GO:0043624) | 3.58564328 |
| 60 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.57234679 |
| 61 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.46439569 |
| 62 | endosome to melanosome transport (GO:0035646) | 3.45796667 |
| 63 | endosome to pigment granule transport (GO:0043485) | 3.45796667 |
| 64 | protein localization to endoplasmic reticulum (GO:0070972) | 3.43355441 |
| 65 | valine metabolic process (GO:0006573) | 3.42455377 |
| 66 | otic vesicle formation (GO:0030916) | 3.32762672 |
| 67 | superoxide anion generation (GO:0042554) | 3.27847380 |
| 68 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.27836636 |
| 69 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) | 3.25260606 |
| 70 | regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) | 3.25260606 |
| 71 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 3.23906534 |
| 72 | L-phenylalanine metabolic process (GO:0006558) | 3.23906534 |
| 73 | negative regulation of JAK-STAT cascade (GO:0046426) | 3.22091139 |
| 74 | N-terminal protein amino acid modification (GO:0031365) | 3.18628937 |
| 75 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 3.17652094 |
| 76 | interkinetic nuclear migration (GO:0022027) | 3.15441894 |
| 77 | regulation of respiratory gaseous exchange (GO:0043576) | 3.12080144 |
| 78 | vesicle fusion (GO:0006906) | 3.10713330 |
| 79 | negative thymic T cell selection (GO:0045060) | 3.10350271 |
| 80 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.07363069 |
| 81 | positive regulation of T cell apoptotic process (GO:0070234) | 3.02970082 |
| 82 | protein complex disassembly (GO:0043241) | 3.02124567 |
| 83 | keratinocyte differentiation (GO:0030216) | 2.99645308 |
| 84 | regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) | 2.95975902 |
| 85 | positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO | 2.95975902 |
| 86 | regulation of proton transport (GO:0010155) | 2.95817148 |
| 87 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 2.93524551 |
| 88 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.92335571 |
| 89 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 2.91277859 |
| 90 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 2.90144028 |
| 91 | antimicrobial humoral response (GO:0019730) | 2.88163029 |
| 92 | endosome to lysosome transport (GO:0008333) | 2.87735611 |
| 93 | positive regulation of positive chemotaxis (GO:0050927) | 2.85299643 |
| 94 | negative T cell selection (GO:0043383) | 2.84473876 |
| 95 | regulation of acute inflammatory response to antigenic stimulus (GO:0002864) | 2.84132645 |
| 96 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.83463839 |
| 97 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.83061861 |
| 98 | dendrite development (GO:0016358) | 2.82075538 |
| 99 | innate immune response in mucosa (GO:0002227) | 2.78183411 |
| 100 | keratinization (GO:0031424) | 11.3132624 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 5.49880876 |
| 2 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 3.41308889 |
| 3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.96756858 |
| 4 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.72253540 |
| 5 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.72253540 |
| 6 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.72253540 |
| 7 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.60614885 |
| 8 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.56215081 |
| 9 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.50401030 |
| 10 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.36728460 |
| 11 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.31248655 |
| 12 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.30484537 |
| 13 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.20747644 |
| 14 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 2.15799624 |
| 15 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 2.11901233 |
| 16 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 2.01766272 |
| 17 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.99931815 |
| 18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.98931298 |
| 19 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.96146380 |
| 20 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.92074450 |
| 21 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.89752362 |
| 22 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.87816359 |
| 23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.87200240 |
| 24 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.79367768 |
| 25 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.73931410 |
| 26 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.71856847 |
| 27 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.70831179 |
| 28 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.58954260 |
| 29 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.57902174 |
| 30 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.53487269 |
| 31 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.50703744 |
| 32 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.50703744 |
| 33 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.50359183 |
| 34 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.49892379 |
| 35 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.48937371 |
| 36 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.47909897 |
| 37 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.46863894 |
| 38 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.45333375 |
| 39 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.44705789 |
| 40 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.44307315 |
| 41 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.44297020 |
| 42 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 1.43739105 |
| 43 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 1.42751497 |
| 44 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.42095204 |
| 45 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.37666914 |
| 46 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.36017328 |
| 47 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.35734494 |
| 48 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.32692650 |
| 49 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.30352677 |
| 50 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.30296485 |
| 51 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.26790153 |
| 52 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.24555845 |
| 53 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.22592460 |
| 54 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.17784520 |
| 55 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.16804900 |
| 56 | GATA1_22025678_ChIP-Seq_K562_Human | 1.15438451 |
| 57 | SPI1_23127762_ChIP-Seq_K562_Human | 1.14654070 |
| 58 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.14086644 |
| 59 | P300_27268052_Chip-Seq_Bcells_Human | 1.12590288 |
| 60 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.11709415 |
| 61 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.11709415 |
| 62 | TP53_22127205_ChIP-Seq_IMR90_Human | 1.11698209 |
| 63 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.09912238 |
| 64 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.09342164 |
| 65 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.08096428 |
| 66 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.07947603 |
| 67 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.07407662 |
| 68 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.06044800 |
| 69 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.05937198 |
| 70 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.05200083 |
| 71 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.03587384 |
| 72 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.03540377 |
| 73 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.03219279 |
| 74 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.02853783 |
| 75 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.02412778 |
| 76 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.02261605 |
| 77 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.01487620 |
| 78 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.00772246 |
| 79 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.98334325 |
| 80 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.97545846 |
| 81 | TP63_22573176_ChIP-Seq_HFKS_Human | 0.94243844 |
| 82 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.94202303 |
| 83 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.93965977 |
| 84 | SA1_27219007_Chip-Seq_Bcells_Human | 0.93860692 |
| 85 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.90696388 |
| 86 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.89217632 |
| 87 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.89079142 |
| 88 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.88955622 |
| 89 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.87920158 |
| 90 | GF1_26923725_Chip-Seq_HPCs_Mouse | 0.87863960 |
| 91 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.87451224 |
| 92 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.87255740 |
| 93 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.86691816 |
| 94 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.85909153 |
| 95 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.85541517 |
| 96 | KAP1_27257070_Chip-Seq_ESCs_Mouse | 0.84979212 |
| 97 | AR_25329375_ChIP-Seq_VCAP_Human | 0.84176706 |
| 98 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.83828424 |
| 99 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83645935 |
| 100 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.83437176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006054_spinal_hemorrhage | 8.62889385 |
| 2 | MP0002796_impaired_skin_barrier | 5.81631558 |
| 3 | MP0002653_abnormal_ependyma_morphology | 5.64648310 |
| 4 | MP0005623_abnormal_meninges_morphology | 5.44876917 |
| 5 | MP0002837_dystrophic_cardiac_calcinosis | 5.27554514 |
| 6 | MP0005275_abnormal_skin_tensile | 4.60310483 |
| 7 | MP0004084_abnormal_cardiac_muscle | 4.30971073 |
| 8 | MP0003279_aneurysm | 4.15378710 |
| 9 | MP0001915_intracranial_hemorrhage | 3.19877489 |
| 10 | MP0005501_abnormal_skin_physiology | 2.79826295 |
| 11 | MP0003941_abnormal_skin_development | 2.53578421 |
| 12 | MP0009379_abnormal_foot_pigmentation | 2.34111961 |
| 13 | MP0004036_abnormal_muscle_relaxation | 2.30184679 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 2.25983115 |
| 15 | MP0004130_abnormal_muscle_cell | 2.01759690 |
| 16 | MP0001346_abnormal_lacrimal_gland | 1.82538853 |
| 17 | MP0004215_abnormal_myocardial_fiber | 1.78178104 |
| 18 | MP0000579_abnormal_nail_morphology | 1.70221144 |
| 19 | MP0003011_delayed_dark_adaptation | 1.56372878 |
| 20 | MP0005377_hearing/vestibular/ear_phenot | 1.52931787 |
| 21 | MP0003878_abnormal_ear_physiology | 1.52931787 |
| 22 | MP0004185_abnormal_adipocyte_glucose | 1.51688923 |
| 23 | MP0000767_abnormal_smooth_muscle | 1.47562159 |
| 24 | MP0004484_altered_response_of | 1.43874326 |
| 25 | MP0002163_abnormal_gland_morphology | 1.32551374 |
| 26 | MP0001986_abnormal_taste_sensitivity | 1.32480666 |
| 27 | MP0003191_abnormal_cellular_cholesterol | 1.28071965 |
| 28 | MP0004885_abnormal_endolymph | 1.25605386 |
| 29 | MP0006292_abnormal_olfactory_placode | 1.23063081 |
| 30 | MP0000678_abnormal_parathyroid_gland | 1.19324208 |
| 31 | MP0009333_abnormal_splenocyte_physiolog | 1.18411426 |
| 32 | MP0005220_abnormal_exocrine_pancreas | 1.16607947 |
| 33 | MP0001216_abnormal_epidermal_layer | 1.15648744 |
| 34 | MP0010155_abnormal_intestine_physiology | 1.15326088 |
| 35 | MP0003186_abnormal_redox_activity | 1.13085072 |
| 36 | MP0003705_abnormal_hypodermis_morpholog | 1.12553278 |
| 37 | MP0003300_gastrointestinal_ulcer | 1.09777246 |
| 38 | MP0010771_integument_phenotype | 1.08727446 |
| 39 | MP0004947_skin_inflammation | 1.07856405 |
| 40 | MP0001764_abnormal_homeostasis | 1.05733904 |
| 41 | MP0009250_abnormal_appendicular_skeleto | 1.03162997 |
| 42 | MP0009765_abnormal_xenobiotic_induced | 1.00934230 |
| 43 | MP0010352_gastrointestinal_tract_polyps | 1.00928046 |
| 44 | MP0002697_abnormal_eye_size | 1.00583347 |
| 45 | MP0004782_abnormal_surfactant_physiolog | 1.00425641 |
| 46 | MP0003195_calcinosis | 0.98786355 |
| 47 | MP0001340_abnormal_eyelid_morphology | 0.93201134 |
| 48 | MP0003633_abnormal_nervous_system | 0.91091293 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 0.89670083 |
| 50 | MP0001286_abnormal_eye_development | 0.88466556 |
| 51 | MP0005165_increased_susceptibility_to | 0.86940692 |
| 52 | MP0001348_abnormal_lacrimal_gland | 0.84762019 |
| 53 | MP0005503_abnormal_tendon_morphology | 0.82832314 |
| 54 | MP0009785_altered_susceptibility_to | 0.80715340 |
| 55 | MP0002693_abnormal_pancreas_physiology | 0.78971931 |
| 56 | MP0008775_abnormal_heart_ventricle | 0.77980098 |
| 57 | MP0001191_abnormal_skin_condition | 0.77612310 |
| 58 | MP0002060_abnormal_skin_morphology | 0.76884693 |
| 59 | MP0005448_abnormal_energy_balance | 0.72844421 |
| 60 | MP0001661_extended_life_span | 0.69901429 |
| 61 | MP0003453_abnormal_keratinocyte_physiol | 0.69867446 |
| 62 | MP0003631_nervous_system_phenotype | 0.69018805 |
| 63 | MP0000377_abnormal_hair_follicle | 0.68326166 |
| 64 | MP0003303_peritoneal_inflammation | 0.68118879 |
| 65 | MP0002160_abnormal_reproductive_system | 0.68083540 |
| 66 | MP0001800_abnormal_humoral_immune | 0.67021853 |
| 67 | MP0001784_abnormal_fluid_regulation | 0.64807177 |
| 68 | MP0005023_abnormal_wound_healing | 0.63016903 |
| 69 | MP0002972_abnormal_cardiac_muscle | 0.62315536 |
| 70 | MP0005379_endocrine/exocrine_gland_phen | 0.60152643 |
| 71 | MP0005197_abnormal_uvea_morphology | 0.59813421 |
| 72 | MP0001188_hyperpigmentation | 0.55418803 |
| 73 | MP0000367_abnormal_coat/_hair | 0.54588244 |
| 74 | MP0005647_abnormal_sex_gland | 0.54074538 |
| 75 | MP0000762_abnormal_tongue_morphology | 0.51129443 |
| 76 | MP0003646_muscle_fatigue | 0.49713366 |
| 77 | MP0004197_abnormal_fetal_growth/weight/ | 0.47349884 |
| 78 | MP0002095_abnormal_skin_pigmentation | 0.45587807 |
| 79 | MP0005334_abnormal_fat_pad | 0.44142387 |
| 80 | MP0009931_abnormal_skin_appearance | 0.43938416 |
| 81 | MP0002723_abnormal_immune_serum | 0.41553965 |
| 82 | MP0005376_homeostasis/metabolism_phenot | 0.41537292 |
| 83 | MP0005385_cardiovascular_system_phenoty | 0.40908829 |
| 84 | MP0001544_abnormal_cardiovascular_syste | 0.40908829 |
| 85 | MP0000685_abnormal_immune_system | 0.40664175 |
| 86 | MP0005193_abnormal_anterior_eye | 0.38971665 |
| 87 | MP0002234_abnormal_pharynx_morphology | 0.37441291 |
| 88 | MP0005375_adipose_tissue_phenotype | 0.36411481 |
| 89 | MP0000477_abnormal_intestine_morphology | 0.35465280 |
| 90 | MP0002106_abnormal_muscle_physiology | 0.35342887 |
| 91 | MP0005620_abnormal_muscle_contractility | 0.34030073 |
| 92 | MP0000428_abnormal_craniofacial_morphol | 0.34028918 |
| 93 | MP0000534_abnormal_ureter_morphology | 0.33743906 |
| 94 | MP0000647_abnormal_sebaceous_gland | 0.32852178 |
| 95 | MP0002896_abnormal_bone_mineralization | 0.32656327 |
| 96 | MP0003866_abnormal_defecation | 0.32615608 |
| 97 | MP0000627_abnormal_mammary_gland | 0.32576739 |
| 98 | MP0000566_synostosis | 0.32428889 |
| 99 | MP0010234_abnormal_vibrissa_follicle | 0.31578443 |
| 100 | MP0005666_abnormal_adipose_tissue | 0.31118746 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of nail color (HP:0100643) | 7.25228099 |
| 2 | Progressive inability to walk (HP:0002505) | 5.62728402 |
| 3 | Increased IgE level (HP:0003212) | 5.62054801 |
| 4 | Abnormality of the axillary hair (HP:0100134) | 5.49826693 |
| 5 | Abnormality of secondary sexual hair (HP:0009888) | 5.49826693 |
| 6 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 5.45972613 |
| 7 | Absent/shortened dynein arms (HP:0200106) | 5.45972613 |
| 8 | Onycholysis (HP:0001806) | 5.29526295 |
| 9 | Premature ovarian failure (HP:0008209) | 5.12125784 |
| 10 | Mutism (HP:0002300) | 5.11273417 |
| 11 | Hypergonadotropic hypogonadism (HP:0000815) | 4.91477204 |
| 12 | Chronic otitis media (HP:0000389) | 4.76874916 |
| 13 | Erythroderma (HP:0001019) | 4.54186507 |
| 14 | Hypotrichosis (HP:0001006) | 4.51495621 |
| 15 | Loss of speech (HP:0002371) | 4.50154515 |
| 16 | Congenital ichthyosiform erythroderma (HP:0007431) | 4.49552717 |
| 17 | Alopecia of scalp (HP:0002293) | 4.47351111 |
| 18 | Abnormal number of erythroid precursors (HP:0012131) | 4.34199279 |
| 19 | Palmoplantar hyperkeratosis (HP:0000972) | 4.24184282 |
| 20 | Corneal erosion (HP:0200020) | 4.12866223 |
| 21 | Palmar hyperkeratosis (HP:0010765) | 3.97873679 |
| 22 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.91264601 |
| 23 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.87776793 |
| 24 | Disinhibition (HP:0000734) | 3.74768362 |
| 25 | Aortic regurgitation (HP:0001659) | 3.65270332 |
| 26 | Plantar hyperkeratosis (HP:0007556) | 3.44424961 |
| 27 | Dyskinesia (HP:0100660) | 3.28867446 |
| 28 | Chronic sinusitis (HP:0011109) | 3.24084403 |
| 29 | Erythema (HP:0010783) | 3.08842572 |
| 30 | Abnormal ciliary motility (HP:0012262) | 3.04206822 |
| 31 | Gangrene (HP:0100758) | 2.99530735 |
| 32 | Absent eyelashes (HP:0000561) | 2.99438088 |
| 33 | Sepsis (HP:0100806) | 2.97490942 |
| 34 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.96103044 |
| 35 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.96103044 |
| 36 | Absent hair (HP:0002298) | 2.84600835 |
| 37 | Hypohidrosis (HP:0000966) | 2.78031679 |
| 38 | Parakeratosis (HP:0001036) | 2.73186950 |
| 39 | Elfin facies (HP:0004428) | 2.52421255 |
| 40 | Sparse eyelashes (HP:0000653) | 2.51299146 |
| 41 | Inability to walk (HP:0002540) | 2.49013771 |
| 42 | Oral leukoplakia (HP:0002745) | 2.47610470 |
| 43 | Palmoplantar keratoderma (HP:0000982) | 2.42416440 |
| 44 | Overriding aorta (HP:0002623) | 2.37027207 |
| 45 | Agammaglobulinemia (HP:0004432) | 2.33090606 |
| 46 | Mitral regurgitation (HP:0001653) | 2.31985263 |
| 47 | Furrowed tongue (HP:0000221) | 2.22516796 |
| 48 | Renovascular hypertension (HP:0100817) | 2.19928695 |
| 49 | Ectropion (HP:0000656) | 2.18359297 |
| 50 | Genetic anticipation (HP:0003743) | 2.17257171 |
| 51 | Rhinitis (HP:0012384) | 2.15023231 |
| 52 | Stomatitis (HP:0010280) | 2.14791610 |
| 53 | Pustule (HP:0200039) | 2.14488466 |
| 54 | Delayed epiphyseal ossification (HP:0002663) | 2.11972684 |
| 55 | Hyperacusis (HP:0010780) | 2.10077936 |
| 56 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.09793940 |
| 57 | Flat cornea (HP:0007720) | 2.08501812 |
| 58 | Submucous cleft hard palate (HP:0000176) | 2.08430194 |
| 59 | Thick nail (HP:0001805) | 2.06710218 |
| 60 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.06040171 |
| 61 | Personality changes (HP:0000751) | 2.00530109 |
| 62 | Right ventricular cardiomyopathy (HP:0011663) | 2.00274815 |
| 63 | Chronic hepatic failure (HP:0100626) | 10.4608368 |
| 64 | Renal duplication (HP:0000075) | 1.99713985 |
| 65 | Enlarged epiphyses (HP:0010580) | 1.99657866 |
| 66 | Bladder diverticulum (HP:0000015) | 1.99264628 |
| 67 | Apathy (HP:0000741) | 1.96933759 |
| 68 | Thin bony cortex (HP:0002753) | 1.96888848 |
| 69 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.94737457 |
| 70 | Chronic diarrhea (HP:0002028) | 1.92606224 |
| 71 | Abnormality of the nasal septum (HP:0000419) | 1.92267474 |
| 72 | Septate vagina (HP:0001153) | 1.91073909 |
| 73 | Pruritus (HP:0000989) | 1.88965887 |
| 74 | Depressed nasal tip (HP:0000437) | 1.87376069 |
| 75 | Inappropriate behavior (HP:0000719) | 1.87346002 |
| 76 | Hypergammaglobulinemia (HP:0010702) | 1.86711848 |
| 77 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.86116126 |
| 78 | Malignant hyperthermia (HP:0002047) | 1.82656109 |
| 79 | Lip pit (HP:0100267) | 1.78226314 |
| 80 | Dysmetric saccades (HP:0000641) | 1.77155226 |
| 81 | Hallux valgus (HP:0001822) | 1.73732857 |
| 82 | Nail dystrophy (HP:0008404) | 1.72609055 |
| 83 | Systemic lupus erythematosus (HP:0002725) | 1.72431478 |
| 84 | Abnormal number of incisors (HP:0011064) | 1.70685175 |
| 85 | Split foot (HP:0001839) | 1.68057627 |
| 86 | Widely patent fontanelles and sutures (HP:0004492) | 1.67933132 |
| 87 | Eczematoid dermatitis (HP:0000976) | 1.67517190 |
| 88 | Abnormality of the diencephalon (HP:0010662) | 1.67347134 |
| 89 | Diminished motivation (HP:0000745) | 1.66532368 |
| 90 | Hepatocellular necrosis (HP:0001404) | 1.65042270 |
| 91 | Abnormality of placental membranes (HP:0011409) | 1.63669217 |
| 92 | Amniotic constriction ring (HP:0009775) | 1.63669217 |
| 93 | Sparse scalp hair (HP:0002209) | 1.62470318 |
| 94 | Hamartoma of the eye (HP:0010568) | 1.62397888 |
| 95 | Deviation of the hallux (HP:0010051) | 1.62042372 |
| 96 | Bulbous nose (HP:0000414) | 1.61395733 |
| 97 | Restlessness (HP:0000711) | 1.59003872 |
| 98 | Anhidrosis (HP:0000970) | 1.58930975 |
| 99 | Insomnia (HP:0100785) | 1.54841538 |
| 100 | Oligodontia (HP:0000677) | 1.53186571 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP3K13 | 6.75982516 |
| 2 | CAMKK1 | 5.78538106 |
| 3 | TXK | 3.45975379 |
| 4 | RIPK4 | 2.98632288 |
| 5 | MAP3K14 | 2.48396915 |
| 6 | LRRK2 | 2.27761670 |
| 7 | SIK2 | 2.16962698 |
| 8 | BRSK2 | 2.07795859 |
| 9 | PASK | 11.5285280 |
| 10 | CAMKK2 | 1.99672418 |
| 11 | MAP4K1 | 1.98852484 |
| 12 | TGFBR1 | 1.56182076 |
| 13 | JAK3 | 1.42895554 |
| 14 | MAP3K7 | 1.25439243 |
| 15 | BTK | 1.12629387 |
| 16 | TYRO3 | 1.01304908 |
| 17 | IKBKB | 0.95514522 |
| 18 | MAPKAPK3 | 0.94007789 |
| 19 | BRSK1 | 0.82336430 |
| 20 | SYK | 0.79436465 |
| 21 | STK38 | 0.78895427 |
| 22 | TEC | 0.77477767 |
| 23 | CHUK | 0.74224762 |
| 24 | ACVR1B | 0.73989380 |
| 25 | NEK2 | 0.69313893 |
| 26 | PAK6 | 0.68090382 |
| 27 | ITK | 0.67963558 |
| 28 | PRKCQ | 0.65371074 |
| 29 | PTK6 | 0.63231920 |
| 30 | SGK223 | 0.61350747 |
| 31 | SGK494 | 0.61350747 |
| 32 | LCK | 0.59490119 |
| 33 | YES1 | 0.58460429 |
| 34 | ZAP70 | 0.58232664 |
| 35 | FRK | 0.57815262 |
| 36 | STK11 | 0.57564040 |
| 37 | BMPR1B | 0.57480622 |
| 38 | PRKAA2 | 0.55975334 |
| 39 | MARK3 | 0.51687262 |
| 40 | ADRBK2 | 0.50812096 |
| 41 | STK4 | 0.48927471 |
| 42 | CLK1 | 0.44516867 |
| 43 | PIK3CG | 0.44424724 |
| 44 | FGR | 0.41692272 |
| 45 | SGK1 | 0.37696046 |
| 46 | PAK2 | 0.35719179 |
| 47 | INSRR | 0.34360051 |
| 48 | PRKCZ | 0.33937763 |
| 49 | JAK2 | 0.32388879 |
| 50 | EEF2K | 0.29036624 |
| 51 | CSNK1A1L | 0.28910628 |
| 52 | PRKCD | 0.28556783 |
| 53 | KIT | 0.28538533 |
| 54 | LYN | 0.26885784 |
| 55 | DYRK2 | 0.25537387 |
| 56 | CSNK1G3 | 0.25368325 |
| 57 | ADRBK1 | 0.25067490 |
| 58 | OBSCN | 0.24214440 |
| 59 | MAPK13 | 0.22875407 |
| 60 | MAPK15 | 0.21777138 |
| 61 | MKNK2 | 0.21188908 |
| 62 | MAPKAPK2 | 0.19453797 |
| 63 | CSNK1G1 | 0.18914888 |
| 64 | MUSK | 0.17064148 |
| 65 | HCK | 0.16604624 |
| 66 | RPS6KB2 | 0.16323576 |
| 67 | RPS6KA5 | 0.15040521 |
| 68 | MAPK12 | 0.14596856 |
| 69 | KDR | 0.14504804 |
| 70 | DMPK | 0.12423170 |
| 71 | ERBB2 | 0.11819795 |
| 72 | FGFR1 | 0.11477037 |
| 73 | IGF1R | 0.11240465 |
| 74 | PDK1 | 0.11172681 |
| 75 | SGK2 | 0.09827121 |
| 76 | TIE1 | 0.09787464 |
| 77 | CSNK1G2 | 0.09769147 |
| 78 | GRK7 | 0.09087408 |
| 79 | GRK1 | 0.08099781 |
| 80 | PRKCA | 0.07332535 |
| 81 | RPS6KA3 | 0.07309767 |
| 82 | FYN | 0.06953293 |
| 83 | MAP4K2 | 0.06839400 |
| 84 | PAK1 | 0.06796218 |
| 85 | FGFR2 | 0.06445254 |
| 86 | MAPK14 | 0.06251459 |
| 87 | AKT3 | 0.04693645 |
| 88 | SRC | 0.03913300 |
| 89 | MAP2K6 | 0.03888365 |
| 90 | MAPK11 | 0.03257105 |
| 91 | GRK6 | 0.02794910 |
| 92 | ERBB4 | 0.02365589 |
| 93 | WNK1 | 0.01804032 |
| 94 | JAK1 | 0.01801406 |
| 95 | PRKACG | 0.01670843 |
| 96 | PDGFRB | 0.01238918 |
| 97 | DDR2 | 0.00729254 |
| 98 | CAMK2B | -0.0069489 |
| 99 | FGFR3 | -0.0047463 |
| 100 | WNK3 | -0.0020191 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 5.75756205 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.04218821 |
| 3 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.90251891 |
| 4 | Galactose metabolism_Homo sapiens_hsa00052 | 2.84243736 |
| 5 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 2.64849163 |
| 6 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 2.43183212 |
| 7 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.37084396 |
| 8 | Cocaine addiction_Homo sapiens_hsa05030 | 2.16969707 |
| 9 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.93557320 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.64747569 |
| 11 | Long-term potentiation_Homo sapiens_hsa04720 | 1.64681162 |
| 12 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 1.61110764 |
| 13 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.60981065 |
| 14 | Phototransduction_Homo sapiens_hsa04744 | 1.59065618 |
| 15 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.51887884 |
| 16 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.50127830 |
| 17 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.49396842 |
| 18 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.49059127 |
| 19 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.44776132 |
| 20 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.43815534 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.28498539 |
| 22 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 1.28159016 |
| 23 | Asthma_Homo sapiens_hsa05310 | 1.27073969 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.26342237 |
| 25 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.19929641 |
| 26 | ABC transporters_Homo sapiens_hsa02010 | 1.19641054 |
| 27 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.19333121 |
| 28 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 1.13473690 |
| 29 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 1.12950853 |
| 30 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.11036543 |
| 31 | Allograft rejection_Homo sapiens_hsa05330 | 1.09670261 |
| 32 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.02689031 |
| 33 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.02501791 |
| 34 | Prostate cancer_Homo sapiens_hsa05215 | 0.99432385 |
| 35 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.98025015 |
| 36 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.97901998 |
| 37 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.96677066 |
| 38 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.94970883 |
| 39 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.94321580 |
| 40 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.92065873 |
| 41 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.91511897 |
| 42 | Insulin secretion_Homo sapiens_hsa04911 | 0.89651686 |
| 43 | Olfactory transduction_Homo sapiens_hsa04740 | 0.86693799 |
| 44 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.84984542 |
| 45 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.83036239 |
| 46 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.78177118 |
| 47 | Pertussis_Homo sapiens_hsa05133 | 0.78162316 |
| 48 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.77084142 |
| 49 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.76324536 |
| 50 | Shigellosis_Homo sapiens_hsa05131 | 0.75787277 |
| 51 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.75409685 |
| 52 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.75377052 |
| 53 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.70861505 |
| 54 | Histidine metabolism_Homo sapiens_hsa00340 | 0.70859819 |
| 55 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.69556767 |
| 56 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.68321177 |
| 57 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.67892578 |
| 58 | Hepatitis B_Homo sapiens_hsa05161 | 0.63362265 |
| 59 | Measles_Homo sapiens_hsa05162 | 0.63030129 |
| 60 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.61763509 |
| 61 | Insulin resistance_Homo sapiens_hsa04931 | 0.61603999 |
| 62 | Apoptosis_Homo sapiens_hsa04210 | 0.58878534 |
| 63 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.58687455 |
| 64 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.58546665 |
| 65 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.57246222 |
| 66 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.57184742 |
| 67 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.55207595 |
| 68 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.54919524 |
| 69 | Renin secretion_Homo sapiens_hsa04924 | 0.52889776 |
| 70 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.52559680 |
| 71 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.52123923 |
| 72 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50606336 |
| 73 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.49970386 |
| 74 | HTLV-I infection_Homo sapiens_hsa05166 | 0.49961242 |
| 75 | Influenza A_Homo sapiens_hsa05164 | 0.47201473 |
| 76 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.47192794 |
| 77 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.47097908 |
| 78 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.46439226 |
| 79 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.46415236 |
| 80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.45923072 |
| 81 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.44651052 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.44466769 |
| 83 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.44019420 |
| 84 | Salivary secretion_Homo sapiens_hsa04970 | 0.43093126 |
| 85 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.42975577 |
| 86 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.42537201 |
| 87 | Viral myocarditis_Homo sapiens_hsa05416 | 0.41735257 |
| 88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41433493 |
| 89 | Amoebiasis_Homo sapiens_hsa05146 | 0.40941116 |
| 90 | Tuberculosis_Homo sapiens_hsa05152 | 0.40647875 |
| 91 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.40471349 |
| 92 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37924572 |
| 93 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37561528 |
| 94 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.36551471 |
| 95 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.36540930 |
| 96 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.36493867 |
| 97 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.35324666 |
| 98 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.34726470 |
| 99 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.34505259 |
| 100 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.34462819 |

