

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.35256758 |
| 2 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.50810569 |
| 3 | cytidine deamination (GO:0009972) | 6.41989180 |
| 4 | cytidine metabolic process (GO:0046087) | 6.41989180 |
| 5 | cytidine catabolic process (GO:0006216) | 6.41989180 |
| 6 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.56527931 |
| 7 | ribosomal small subunit assembly (GO:0000028) | 5.37264807 |
| 8 | ATP synthesis coupled proton transport (GO:0015986) | 4.87552136 |
| 9 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.87552136 |
| 10 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.74198392 |
| 11 | regulation of regulatory T cell differentiation (GO:0045589) | 4.35442002 |
| 12 | viral transcription (GO:0019083) | 4.14093125 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.05690269 |
| 14 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.01571727 |
| 15 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.98741346 |
| 16 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.98741346 |
| 17 | translational termination (GO:0006415) | 3.96169637 |
| 18 | respiratory electron transport chain (GO:0022904) | 3.77398974 |
| 19 | electron transport chain (GO:0022900) | 3.73740114 |
| 20 | translational elongation (GO:0006414) | 3.72902102 |
| 21 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.67205311 |
| 22 | proteasome assembly (GO:0043248) | 3.61887335 |
| 23 | protein targeting to ER (GO:0045047) | 3.58959873 |
| 24 | cotranslational protein targeting to membrane (GO:0006613) | 3.58707617 |
| 25 | protein complex biogenesis (GO:0070271) | 3.57916309 |
| 26 | protein neddylation (GO:0045116) | 3.54565237 |
| 27 | sequestering of actin monomers (GO:0042989) | 3.53194753 |
| 28 | maturation of SSU-rRNA (GO:0030490) | 3.51712497 |
| 29 | termination of RNA polymerase III transcription (GO:0006386) | 3.48895215 |
| 30 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.48895215 |
| 31 | rRNA modification (GO:0000154) | 3.48291707 |
| 32 | behavioral response to nicotine (GO:0035095) | 3.45538304 |
| 33 | ribosomal large subunit biogenesis (GO:0042273) | 3.44357302 |
| 34 | protein localization to endoplasmic reticulum (GO:0070972) | 3.43543087 |
| 35 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.43255940 |
| 36 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.42817174 |
| 37 | NADH dehydrogenase complex assembly (GO:0010257) | 3.42817174 |
| 38 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.42817174 |
| 39 | ribosomal small subunit biogenesis (GO:0042274) | 3.39605534 |
| 40 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.30792974 |
| 41 | pseudouridine synthesis (GO:0001522) | 3.22781891 |
| 42 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.18451302 |
| 43 | translation (GO:0006412) | 3.17845508 |
| 44 | chaperone-mediated protein transport (GO:0072321) | 3.17103603 |
| 45 | metallo-sulfur cluster assembly (GO:0031163) | 3.13808540 |
| 46 | iron-sulfur cluster assembly (GO:0016226) | 3.13808540 |
| 47 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.11634117 |
| 48 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.11059825 |
| 49 | pyrimidine nucleoside catabolic process (GO:0046135) | 3.06931380 |
| 50 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.04612866 |
| 51 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.02692379 |
| 52 | purine nucleotide salvage (GO:0032261) | 3.01387473 |
| 53 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.99850677 |
| 54 | GTP biosynthetic process (GO:0006183) | 2.99203999 |
| 55 | translational initiation (GO:0006413) | 2.98926444 |
| 56 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.97143257 |
| 57 | cellular component biogenesis (GO:0044085) | 2.96506040 |
| 58 | pyrimidine ribonucleoside metabolic process (GO:0046131) | 2.95016050 |
| 59 | platelet dense granule organization (GO:0060155) | 2.94464032 |
| 60 | negative regulation by host of viral transcription (GO:0043922) | 2.94222417 |
| 61 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.94149338 |
| 62 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.93826586 |
| 63 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.93543764 |
| 64 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.92077350 |
| 65 | viral life cycle (GO:0019058) | 2.91718561 |
| 66 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.91543924 |
| 67 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.89443198 |
| 68 | ATP biosynthetic process (GO:0006754) | 2.89124952 |
| 69 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.88545523 |
| 70 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.88362108 |
| 71 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.88362108 |
| 72 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.88362108 |
| 73 | cellular protein complex disassembly (GO:0043624) | 2.85792128 |
| 74 | positive regulation of T cell apoptotic process (GO:0070234) | 2.85074706 |
| 75 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.84807710 |
| 76 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.84807710 |
| 77 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.83399750 |
| 78 | positive regulation of interleukin-17 production (GO:0032740) | 2.82496062 |
| 79 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.80550878 |
| 80 | peptidyl-histidine modification (GO:0018202) | 2.80539231 |
| 81 | negative regulation of T cell apoptotic process (GO:0070233) | 2.79068252 |
| 82 | mannosylation (GO:0097502) | 2.78757166 |
| 83 | ubiquinone biosynthetic process (GO:0006744) | 2.74052399 |
| 84 | rRNA processing (GO:0006364) | 2.73337719 |
| 85 | rRNA methylation (GO:0031167) | 2.72814050 |
| 86 | hydrogen ion transmembrane transport (GO:1902600) | 2.72755090 |
| 87 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.72057230 |
| 88 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.72057230 |
| 89 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.72023595 |
| 90 | respiratory chain complex IV assembly (GO:0008535) | 2.70566673 |
| 91 | regulation of interleukin-8 secretion (GO:2000482) | 2.68654158 |
| 92 | intracellular protein transmembrane import (GO:0044743) | 2.68612535 |
| 93 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.67879353 |
| 94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.66027976 |
| 95 | rRNA metabolic process (GO:0016072) | 2.65792986 |
| 96 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.63710234 |
| 97 | protein-cofactor linkage (GO:0018065) | 2.62232241 |
| 98 | positive regulation of tolerance induction (GO:0002645) | 2.62075104 |
| 99 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 2.58018164 |
| 100 | L-fucose metabolic process (GO:0042354) | 2.57924280 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 5.65467906 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.94772149 |
| 3 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.89236004 |
| 4 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.65209152 |
| 5 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.51969692 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.39576438 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 3.31954096 |
| 8 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.28885740 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.01931617 |
| 10 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.79320875 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.73997033 |
| 12 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.73173287 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.72053346 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.59059926 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.20595535 |
| 16 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.13409252 |
| 17 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.11141255 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.03923201 |
| 19 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.99495233 |
| 20 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.92605285 |
| 21 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.91477057 |
| 22 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.78449466 |
| 23 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.68659427 |
| 24 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.67721328 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.60362920 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.59365384 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.59359730 |
| 28 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53474466 |
| 29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.49934368 |
| 30 | MYB_26560356_Chip-Seq_TH2_Human | 1.45831096 |
| 31 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.43362752 |
| 32 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.42021813 |
| 33 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.41426477 |
| 34 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.41340815 |
| 35 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.37612574 |
| 36 | GATA3_26560356_Chip-Seq_TH2_Human | 1.35270102 |
| 37 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.34716083 |
| 38 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.34716083 |
| 39 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.34156640 |
| 40 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.34049650 |
| 41 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.31309579 |
| 42 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.30808201 |
| 43 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.29166912 |
| 44 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.28750105 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.27200167 |
| 46 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.27111868 |
| 47 | NCOR_22424771_ChIP-Seq_293T_Human | 1.26897775 |
| 48 | AR_20517297_ChIP-Seq_VCAP_Human | 1.26148344 |
| 49 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.25207118 |
| 50 | EWS_26573619_Chip-Seq_HEK293_Human | 1.25162576 |
| 51 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.25031887 |
| 52 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.24743846 |
| 53 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.24565479 |
| 54 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.21725543 |
| 55 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20777248 |
| 56 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.19454097 |
| 57 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.18678524 |
| 58 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18550446 |
| 59 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.18266296 |
| 60 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.18215994 |
| 61 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.17684732 |
| 62 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.16440383 |
| 63 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.14475494 |
| 64 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.14412238 |
| 65 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.12488735 |
| 66 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.12259555 |
| 67 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.11559249 |
| 68 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.10996445 |
| 69 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.09706434 |
| 70 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.08912280 |
| 71 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08344112 |
| 72 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.08061272 |
| 73 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.07682578 |
| 74 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.06252999 |
| 75 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.04928124 |
| 76 | ERA_21632823_ChIP-Seq_H3396_Human | 1.03332193 |
| 77 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.02654112 |
| 78 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.02132270 |
| 79 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.01996734 |
| 80 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.01420068 |
| 81 | FUS_26573619_Chip-Seq_HEK293_Human | 1.01006515 |
| 82 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.00947085 |
| 83 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.00923404 |
| 84 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.00181592 |
| 85 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.99591125 |
| 86 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.99206466 |
| 87 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.99203082 |
| 88 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.98139946 |
| 89 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.97418344 |
| 90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.97059249 |
| 91 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.95987598 |
| 92 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.95006489 |
| 93 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.95006489 |
| 94 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.94961407 |
| 95 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.93880164 |
| 96 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.93565623 |
| 97 | CTCF_20526341_ChIP-Seq_ESCs_Human | 0.93273618 |
| 98 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.92141795 |
| 99 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.92040240 |
| 100 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.91480647 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 5.19639816 |
| 2 | MP0005671_abnormal_response_to | 4.02042911 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.04408392 |
| 4 | MP0009333_abnormal_splenocyte_physiolog | 2.45864592 |
| 5 | MP0009785_altered_susceptibility_to | 2.35083508 |
| 6 | MP0006292_abnormal_olfactory_placode | 2.32224947 |
| 7 | MP0002163_abnormal_gland_morphology | 2.21552796 |
| 8 | MP0004147_increased_porphyrin_level | 2.08577690 |
| 9 | MP0000685_abnormal_immune_system | 2.04581761 |
| 10 | MP0002102_abnormal_ear_morphology | 2.03525887 |
| 11 | MP0005646_abnormal_pituitary_gland | 1.92355049 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 1.91452887 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 1.88803666 |
| 14 | MP0001800_abnormal_humoral_immune | 1.88163227 |
| 15 | MP0003806_abnormal_nucleotide_metabolis | 1.86456664 |
| 16 | MP0001986_abnormal_taste_sensitivity | 1.85282215 |
| 17 | MP0008872_abnormal_physiological_respon | 1.83642003 |
| 18 | MP0001790_abnormal_immune_system | 1.83470236 |
| 19 | MP0005387_immune_system_phenotype | 1.83470236 |
| 20 | MP0002837_dystrophic_cardiac_calcinosis | 1.80078931 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.77508233 |
| 22 | MP0005000_abnormal_immune_tolerance | 1.76925701 |
| 23 | MP0003763_abnormal_thymus_physiology | 1.73803260 |
| 24 | MP0003646_muscle_fatigue | 1.71597552 |
| 25 | MP0001188_hyperpigmentation | 1.70562789 |
| 26 | MP0001873_stomach_inflammation | 1.68741608 |
| 27 | MP0006072_abnormal_retinal_apoptosis | 1.59294745 |
| 28 | MP0005389_reproductive_system_phenotype | 1.57944862 |
| 29 | MP0005379_endocrine/exocrine_gland_phen | 1.57818447 |
| 30 | MP0002723_abnormal_immune_serum | 1.53132200 |
| 31 | MP0008058_abnormal_DNA_repair | 1.52993918 |
| 32 | MP0005360_urolithiasis | 1.52872941 |
| 33 | MP0002420_abnormal_adaptive_immunity | 1.50058762 |
| 34 | MP0003878_abnormal_ear_physiology | 1.49107965 |
| 35 | MP0005377_hearing/vestibular/ear_phenot | 1.49107965 |
| 36 | MP0005551_abnormal_eye_electrophysiolog | 1.47945436 |
| 37 | MP0001968_abnormal_touch/_nociception | 1.47739056 |
| 38 | MP0004145_abnormal_muscle_electrophysio | 1.46084837 |
| 39 | MP0005645_abnormal_hypothalamus_physiol | 1.45555583 |
| 40 | MP0000372_irregular_coat_pigmentation | 1.43314732 |
| 41 | MP0001819_abnormal_immune_cell | 1.43040090 |
| 42 | MP0002160_abnormal_reproductive_system | 1.40314648 |
| 43 | MP0005025_abnormal_response_to | 1.39934056 |
| 44 | MP0001919_abnormal_reproductive_system | 1.39146740 |
| 45 | MP0002006_tumorigenesis | 1.38182528 |
| 46 | MP0002166_altered_tumor_susceptibility | 1.33171466 |
| 47 | MP0002095_abnormal_skin_pigmentation | 1.33106803 |
| 48 | MP0005075_abnormal_melanosome_morpholog | 1.32909326 |
| 49 | MP0005085_abnormal_gallbladder_physiolo | 1.30695551 |
| 50 | MP0008875_abnormal_xenobiotic_pharmacok | 1.30434493 |
| 51 | MP0003866_abnormal_defecation | 1.28558227 |
| 52 | MP0010155_abnormal_intestine_physiology | 1.27750099 |
| 53 | MP0002736_abnormal_nociception_after | 1.27484977 |
| 54 | MP0004885_abnormal_endolymph | 1.21598095 |
| 55 | MP0003252_abnormal_bile_duct | 1.21371899 |
| 56 | MP0009764_decreased_sensitivity_to | 1.21280814 |
| 57 | MP0003186_abnormal_redox_activity | 1.19835912 |
| 58 | MP0000716_abnormal_immune_system | 1.19413315 |
| 59 | MP0002398_abnormal_bone_marrow | 1.18962214 |
| 60 | MP0002452_abnormal_antigen_presenting | 1.17090591 |
| 61 | MP0008877_abnormal_DNA_methylation | 1.13434448 |
| 62 | MP0001845_abnormal_inflammatory_respons | 1.12956000 |
| 63 | MP0002876_abnormal_thyroid_physiology | 1.12877375 |
| 64 | MP0002638_abnormal_pupillary_reflex | 1.11932192 |
| 65 | MP0002277_abnormal_respiratory_mucosa | 1.11128462 |
| 66 | MP0003195_calcinosis | 1.09214616 |
| 67 | MP0001905_abnormal_dopamine_level | 1.06646427 |
| 68 | MP0000689_abnormal_spleen_morphology | 1.02185743 |
| 69 | MP0004142_abnormal_muscle_tone | 1.02100988 |
| 70 | MP0005174_abnormal_tail_pigmentation | 0.99640784 |
| 71 | MP0001764_abnormal_homeostasis | 0.97274377 |
| 72 | MP0002429_abnormal_blood_cell | 0.97199878 |
| 73 | MP0005636_abnormal_mineral_homeostasis | 0.97136136 |
| 74 | MP0003436_decreased_susceptibility_to | 0.96706753 |
| 75 | MP0002405_respiratory_system_inflammati | 0.96254863 |
| 76 | MP0006036_abnormal_mitochondrial_physio | 0.95930192 |
| 77 | MP0001853_heart_inflammation | 0.95835438 |
| 78 | MP0003786_premature_aging | 0.95698031 |
| 79 | MP0005410_abnormal_fertilization | 0.93119593 |
| 80 | MP0000703_abnormal_thymus_morphology | 0.93056134 |
| 81 | MP0002722_abnormal_immune_system | 0.91073531 |
| 82 | MP0002693_abnormal_pancreas_physiology | 0.88149189 |
| 83 | MP0008995_early_reproductive_senescence | 0.86518310 |
| 84 | MP0003693_abnormal_embryo_hatching | 0.85528187 |
| 85 | MP0001440_abnormal_grooming_behavior | 0.84882850 |
| 86 | MP0001485_abnormal_pinna_reflex | 0.82682392 |
| 87 | MP0002272_abnormal_nervous_system | 0.81969224 |
| 88 | MP0005253_abnormal_eye_physiology | 0.81528185 |
| 89 | MP0005332_abnormal_amino_acid | 0.80569288 |
| 90 | MP0008469_abnormal_protein_level | 0.79920168 |
| 91 | MP0000631_abnormal_neuroendocrine_gland | 0.78143551 |
| 92 | MP0006082_CNS_inflammation | 0.75228004 |
| 93 | MP0001663_abnormal_digestive_system | 0.74523113 |
| 94 | MP0001661_extended_life_span | 0.74356035 |
| 95 | MP0002132_abnormal_respiratory_system | 0.73656820 |
| 96 | MP0009643_abnormal_urine_homeostasis | 0.73329521 |
| 97 | MP0003567_abnormal_fetal_cardiomyocyte | 0.72109282 |
| 98 | MP0002938_white_spotting | 0.72073738 |
| 99 | MP0002933_joint_inflammation | 0.70991648 |
| 100 | MP0001765_abnormal_ion_homeostasis | 0.70736836 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.59582481 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.36261145 |
| 3 | Mitochondrial inheritance (HP:0001427) | 4.32152844 |
| 4 | Aplastic anemia (HP:0001915) | 4.21199555 |
| 5 | Increased CSF lactate (HP:0002490) | 3.85644328 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.82688452 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.73180436 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.66082111 |
| 9 | Increased hepatocellular lipid droplets (HP:0006565) | 3.61842591 |
| 10 | 3-Methylglutaconic aciduria (HP:0003535) | 3.61413419 |
| 11 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.59892103 |
| 12 | Acute encephalopathy (HP:0006846) | 3.59723955 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.50704813 |
| 14 | Hepatic necrosis (HP:0002605) | 3.35659812 |
| 15 | Congenital stationary night blindness (HP:0007642) | 3.34745894 |
| 16 | IgG deficiency (HP:0004315) | 3.30461731 |
| 17 | Lipid accumulation in hepatocytes (HP:0006561) | 3.27081282 |
| 18 | Increased IgM level (HP:0003496) | 3.18699485 |
| 19 | Pancreatic cysts (HP:0001737) | 3.16606997 |
| 20 | Abnormality of alanine metabolism (HP:0010916) | 3.08242340 |
| 21 | Hyperalaninemia (HP:0003348) | 3.08242340 |
| 22 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.08242340 |
| 23 | Cerebral edema (HP:0002181) | 3.05159071 |
| 24 | Renal Fanconi syndrome (HP:0001994) | 3.00554662 |
| 25 | Increased serum lactate (HP:0002151) | 2.95858006 |
| 26 | Abnormality of midbrain morphology (HP:0002418) | 2.92041293 |
| 27 | Molar tooth sign on MRI (HP:0002419) | 2.92041293 |
| 28 | Attenuation of retinal blood vessels (HP:0007843) | 2.88192185 |
| 29 | Pendular nystagmus (HP:0012043) | 2.83919964 |
| 30 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.82993334 |
| 31 | Optic disc pallor (HP:0000543) | 2.82962943 |
| 32 | Stomatitis (HP:0010280) | 2.80630234 |
| 33 | True hermaphroditism (HP:0010459) | 2.80462262 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.78762766 |
| 35 | Decreased central vision (HP:0007663) | 2.75511836 |
| 36 | Exertional dyspnea (HP:0002875) | 2.62035044 |
| 37 | Lactic acidosis (HP:0003128) | 2.59391106 |
| 38 | Constricted visual fields (HP:0001133) | 2.58003427 |
| 39 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.56910176 |
| 40 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.56623123 |
| 41 | Pancreatic fibrosis (HP:0100732) | 2.51514770 |
| 42 | Severe combined immunodeficiency (HP:0004430) | 2.49611575 |
| 43 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.44327275 |
| 44 | Abnormality of T cell number (HP:0011839) | 2.39139263 |
| 45 | Abnormal number of erythroid precursors (HP:0012131) | 2.38874313 |
| 46 | Macrocytic anemia (HP:0001972) | 2.38036762 |
| 47 | Abnormality of B cell number (HP:0010975) | 2.37575885 |
| 48 | Abolished electroretinogram (ERG) (HP:0000550) | 2.36838558 |
| 49 | Increased muscle lipid content (HP:0009058) | 2.33040418 |
| 50 | Hypoproteinemia (HP:0003075) | 2.29368561 |
| 51 | T lymphocytopenia (HP:0005403) | 2.28628108 |
| 52 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.28505295 |
| 53 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.28505295 |
| 54 | Reticulocytopenia (HP:0001896) | 2.28172116 |
| 55 | Respiratory failure (HP:0002878) | 2.26514841 |
| 56 | Abnormality of T cells (HP:0002843) | 2.21956767 |
| 57 | Congenital, generalized hypertrichosis (HP:0004540) | 2.16552682 |
| 58 | Abnormality of renal resorption (HP:0011038) | 2.15679749 |
| 59 | Hyperphosphaturia (HP:0003109) | 2.14975445 |
| 60 | Pancytopenia (HP:0001876) | 2.14665797 |
| 61 | Lethargy (HP:0001254) | 2.12299461 |
| 62 | Autoimmune hemolytic anemia (HP:0001890) | 2.11486455 |
| 63 | Type II lissencephaly (HP:0007260) | 2.10437833 |
| 64 | Increased corneal curvature (HP:0100692) | 2.03759575 |
| 65 | Keratoconus (HP:0000563) | 2.03759575 |
| 66 | Exercise intolerance (HP:0003546) | 1.99852658 |
| 67 | Type 2 muscle fiber atrophy (HP:0003554) | 1.98988200 |
| 68 | Respiratory difficulties (HP:0002880) | 1.98884943 |
| 69 | Acute hepatic failure (HP:0006554) | 1.98829906 |
| 70 | Thyroiditis (HP:0100646) | 1.98274438 |
| 71 | Microretrognathia (HP:0000308) | 1.97715931 |
| 72 | Type I transferrin isoform profile (HP:0003642) | 1.96742580 |
| 73 | Glycosuria (HP:0003076) | 1.94797823 |
| 74 | Abnormality of urine glucose concentration (HP:0011016) | 1.94797823 |
| 75 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.91836951 |
| 76 | Encephalitis (HP:0002383) | 1.91112847 |
| 77 | Asplenia (HP:0001746) | 1.90947362 |
| 78 | Abnormality of eosinophils (HP:0001879) | 1.90796211 |
| 79 | Abnormality of T cell physiology (HP:0011840) | 1.89872587 |
| 80 | Oral leukoplakia (HP:0002745) | 1.88330227 |
| 81 | Leukodystrophy (HP:0002415) | 1.88293247 |
| 82 | Colon cancer (HP:0003003) | 1.86631533 |
| 83 | Cystic liver disease (HP:0006706) | 1.85759273 |
| 84 | Chronic sinusitis (HP:0011109) | 1.85630266 |
| 85 | Pallor (HP:0000980) | 1.85522852 |
| 86 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.84701579 |
| 87 | Nephronophthisis (HP:0000090) | 1.84402889 |
| 88 | B lymphocytopenia (HP:0010976) | 1.84140132 |
| 89 | Cerebral hypomyelination (HP:0006808) | 1.79259048 |
| 90 | Muscle fiber atrophy (HP:0100295) | 1.78709923 |
| 91 | Sclerocornea (HP:0000647) | 1.77994093 |
| 92 | Delayed CNS myelination (HP:0002188) | 1.77853976 |
| 93 | Combined immunodeficiency (HP:0005387) | 1.76920906 |
| 94 | Hypoalbuminemia (HP:0003073) | 1.75323723 |
| 95 | Abnormal albumin level (HP:0012116) | 1.75323723 |
| 96 | Ketosis (HP:0001946) | 1.74079962 |
| 97 | CNS demyelination (HP:0007305) | 1.73412436 |
| 98 | Abnormality of serum amino acid levels (HP:0003112) | 1.72682861 |
| 99 | Abnormality of the pons (HP:0007361) | 1.71434124 |
| 100 | Abnormal urine phosphate concentration (HP:0012599) | 1.71105473 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 3.71214013 |
| 2 | ZAK | 3.54291287 |
| 3 | KDR | 3.34305981 |
| 4 | BCKDK | 3.23924796 |
| 5 | VRK2 | 2.97896901 |
| 6 | NUAK1 | 2.63782723 |
| 7 | ADRBK2 | 2.58848054 |
| 8 | TIE1 | 2.50841545 |
| 9 | GRK1 | 2.37049793 |
| 10 | TLK1 | 2.30315992 |
| 11 | WNK4 | 2.20224805 |
| 12 | MAP4K1 | 2.19065575 |
| 13 | STK16 | 2.11674530 |
| 14 | VRK1 | 2.01347813 |
| 15 | TEC | 2.00458450 |
| 16 | NME2 | 1.92351741 |
| 17 | ITK | 1.89946341 |
| 18 | MAP4K2 | 1.83674018 |
| 19 | TESK2 | 1.79319046 |
| 20 | TAOK3 | 1.72982289 |
| 21 | MAP3K12 | 1.62321106 |
| 22 | MST4 | 1.58155815 |
| 23 | FRK | 1.42614594 |
| 24 | PINK1 | 1.40194492 |
| 25 | PASK | 1.38870560 |
| 26 | PRKCQ | 1.32974189 |
| 27 | STK39 | 1.28018033 |
| 28 | MAP3K11 | 1.27265597 |
| 29 | MAP2K6 | 1.17330446 |
| 30 | WNK3 | 1.09273836 |
| 31 | DYRK2 | 1.08914870 |
| 32 | GRK6 | 1.06747561 |
| 33 | FES | 1.04195919 |
| 34 | SYK | 1.02771391 |
| 35 | IKBKB | 1.02614386 |
| 36 | PIK3CG | 1.00892399 |
| 37 | LCK | 0.99928958 |
| 38 | TAF1 | 0.97770213 |
| 39 | MUSK | 0.96029897 |
| 40 | KIT | 0.93139352 |
| 41 | MYLK | 0.91530288 |
| 42 | CDK19 | 0.88425598 |
| 43 | TESK1 | 0.87421683 |
| 44 | BMPR2 | 0.87240806 |
| 45 | NME1 | 0.86051867 |
| 46 | EIF2AK1 | 0.84785721 |
| 47 | BTK | 0.84669134 |
| 48 | DAPK1 | 0.84595273 |
| 49 | LIMK1 | 0.83307263 |
| 50 | ACVR1B | 0.82697024 |
| 51 | OXSR1 | 0.82153833 |
| 52 | PIK3CA | 0.79299022 |
| 53 | ADRBK1 | 0.78405304 |
| 54 | GRK7 | 0.76125974 |
| 55 | TRIM28 | 0.73983449 |
| 56 | INSRR | 0.72843570 |
| 57 | AKT3 | 0.71754920 |
| 58 | RPS6KA5 | 0.70386162 |
| 59 | CSK | 0.68472908 |
| 60 | LYN | 0.68098301 |
| 61 | PLK3 | 0.64968763 |
| 62 | IKBKE | 0.64308088 |
| 63 | MAPKAPK3 | 0.62044798 |
| 64 | BMPR1B | 0.60927292 |
| 65 | EIF2AK3 | 0.59476174 |
| 66 | JAK3 | 0.58532770 |
| 67 | BUB1 | 0.58215224 |
| 68 | DAPK3 | 0.56832018 |
| 69 | PLK4 | 0.54226485 |
| 70 | PIM1 | 0.53498644 |
| 71 | RPS6KA4 | 0.52171104 |
| 72 | PHKG1 | 0.50516593 |
| 73 | PHKG2 | 0.50516593 |
| 74 | PRKCA | 0.48589928 |
| 75 | CSNK2A2 | 0.47334552 |
| 76 | CSNK2A1 | 0.47134361 |
| 77 | PRKACA | 0.47040212 |
| 78 | TSSK6 | 0.46729744 |
| 79 | PRKCE | 0.46535276 |
| 80 | CAMKK2 | 0.45657243 |
| 81 | DAPK2 | 0.45551063 |
| 82 | PIM2 | 0.44763050 |
| 83 | TYRO3 | 0.44706516 |
| 84 | OBSCN | 0.44328189 |
| 85 | ABL2 | 0.42829589 |
| 86 | SCYL2 | 0.42297561 |
| 87 | PRKCG | 0.40775786 |
| 88 | ATR | 0.40633700 |
| 89 | CSNK1G3 | 0.40278717 |
| 90 | IGF1R | 0.37738036 |
| 91 | CSNK1A1 | 0.37037281 |
| 92 | CCNB1 | 0.36671638 |
| 93 | RPS6KB2 | 0.34913481 |
| 94 | RIPK4 | 0.34811717 |
| 95 | AURKB | 0.34135614 |
| 96 | PRKCH | 0.32365615 |
| 97 | TGFBR1 | 0.31971335 |
| 98 | CSF1R | 0.31927470 |
| 99 | MAP3K5 | 0.31898873 |
| 100 | STK38L | 0.31614085 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.07837252 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.04262720 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.77013800 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.44306494 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 3.04736972 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.99764871 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.46940738 |
| 8 | Allograft rejection_Homo sapiens_hsa05330 | 2.32159414 |
| 9 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.27894385 |
| 10 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.06114514 |
| 11 | Huntingtons disease_Homo sapiens_hsa05016 | 2.04210122 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.03710926 |
| 13 | Alzheimers disease_Homo sapiens_hsa05010 | 1.96732292 |
| 14 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.92905980 |
| 15 | Asthma_Homo sapiens_hsa05310 | 1.91704457 |
| 16 | Protein export_Homo sapiens_hsa03060 | 1.87895445 |
| 17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.83614607 |
| 18 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.77355230 |
| 19 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.67129488 |
| 20 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.59347052 |
| 21 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.49325838 |
| 22 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.49271922 |
| 23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.49136062 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.47775749 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.47128920 |
| 26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.45941811 |
| 27 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.40938876 |
| 28 | RNA degradation_Homo sapiens_hsa03018 | 1.39831641 |
| 29 | Sulfur relay system_Homo sapiens_hsa04122 | 1.31703496 |
| 30 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.29667424 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.29603662 |
| 32 | Phototransduction_Homo sapiens_hsa04744 | 1.29549186 |
| 33 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.22246933 |
| 34 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.21065754 |
| 35 | Homologous recombination_Homo sapiens_hsa03440 | 1.15726674 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.13851234 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.09008098 |
| 38 | Peroxisome_Homo sapiens_hsa04146 | 1.06913339 |
| 39 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.03557940 |
| 40 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.98066089 |
| 41 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.94689438 |
| 42 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.94644669 |
| 43 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.93147605 |
| 44 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.89169502 |
| 45 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.86297282 |
| 46 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.83168908 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.82613844 |
| 48 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.82135850 |
| 49 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.82047460 |
| 50 | RNA transport_Homo sapiens_hsa03013 | 0.79919994 |
| 51 | Basal transcription factors_Homo sapiens_hsa03022 | 0.79588892 |
| 52 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.78699770 |
| 53 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.70054271 |
| 54 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.69722778 |
| 55 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.69066058 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.68995592 |
| 57 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.68801580 |
| 58 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.68779243 |
| 59 | Base excision repair_Homo sapiens_hsa03410 | 0.64488278 |
| 60 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.62750680 |
| 61 | Retinol metabolism_Homo sapiens_hsa00830 | 0.61968261 |
| 62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.61343332 |
| 63 | DNA replication_Homo sapiens_hsa03030 | 0.58928843 |
| 64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.58462265 |
| 65 | Spliceosome_Homo sapiens_hsa03040 | 0.58374593 |
| 66 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.56109321 |
| 67 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.55767395 |
| 68 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.55439176 |
| 69 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.54944044 |
| 70 | Viral myocarditis_Homo sapiens_hsa05416 | 0.53404479 |
| 71 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.52817492 |
| 72 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.52764984 |
| 73 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52697844 |
| 74 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.52666710 |
| 75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.51848193 |
| 76 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.51839942 |
| 77 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51728984 |
| 78 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.49050136 |
| 79 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47008271 |
| 80 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.46834976 |
| 81 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.45350229 |
| 82 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.45103045 |
| 83 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44600588 |
| 84 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.42928122 |
| 85 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.38391661 |
| 86 | Measles_Homo sapiens_hsa05162 | 0.38025118 |
| 87 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.37917542 |
| 88 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36577355 |
| 89 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.34298106 |
| 90 | Mismatch repair_Homo sapiens_hsa03430 | 0.34285290 |
| 91 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.33795483 |
| 92 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.33219446 |
| 93 | Nicotine addiction_Homo sapiens_hsa05033 | 0.32671118 |
| 94 | Mineral absorption_Homo sapiens_hsa04978 | 0.31439666 |
| 95 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.30632229 |
| 96 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.27600893 |
| 97 | Taste transduction_Homo sapiens_hsa04742 | 0.25951499 |
| 98 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.23783539 |
| 99 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.23607101 |
| 100 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.21737344 |

