

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 7.19033671 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 5.90173539 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.82385603 |
| 4 | cytidine catabolic process (GO:0006216) | 5.37450611 |
| 5 | cytidine deamination (GO:0009972) | 5.37450611 |
| 6 | cytidine metabolic process (GO:0046087) | 5.37450611 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 5.08622394 |
| 8 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.69699369 |
| 9 | ATP synthesis coupled proton transport (GO:0015986) | 4.69699369 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.69155392 |
| 11 | viral transcription (GO:0019083) | 4.67704834 |
| 12 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.61811857 |
| 13 | translational termination (GO:0006415) | 4.51434654 |
| 14 | translational elongation (GO:0006414) | 4.16394192 |
| 15 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 4.11324071 |
| 16 | cotranslational protein targeting to membrane (GO:0006613) | 4.05007098 |
| 17 | ribosomal large subunit biogenesis (GO:0042273) | 4.03558431 |
| 18 | protein targeting to ER (GO:0045047) | 4.01984682 |
| 19 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.82318374 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 3.81558766 |
| 21 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.76219849 |
| 22 | ribosomal small subunit biogenesis (GO:0042274) | 3.73037265 |
| 23 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.68766880 |
| 24 | protein neddylation (GO:0045116) | 3.66595068 |
| 25 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.66165089 |
| 26 | respiratory electron transport chain (GO:0022904) | 3.62910039 |
| 27 | electron transport chain (GO:0022900) | 3.60597308 |
| 28 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.56352004 |
| 29 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.56352004 |
| 30 | regulation of regulatory T cell differentiation (GO:0045589) | 3.52373578 |
| 31 | proteasome assembly (GO:0043248) | 3.49536447 |
| 32 | sequestering of actin monomers (GO:0042989) | 3.49532164 |
| 33 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.49050286 |
| 34 | platelet dense granule organization (GO:0060155) | 3.38339308 |
| 35 | viral life cycle (GO:0019058) | 3.37080784 |
| 36 | translational initiation (GO:0006413) | 3.33517598 |
| 37 | cellular protein complex disassembly (GO:0043624) | 3.32391010 |
| 38 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.29727928 |
| 39 | translation (GO:0006412) | 3.25918810 |
| 40 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.22922908 |
| 41 | chaperone-mediated protein transport (GO:0072321) | 3.20218708 |
| 42 | iron-sulfur cluster assembly (GO:0016226) | 3.18271772 |
| 43 | metallo-sulfur cluster assembly (GO:0031163) | 3.18271772 |
| 44 | behavioral response to nicotine (GO:0035095) | 3.11608774 |
| 45 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.09844607 |
| 46 | protein complex biogenesis (GO:0070271) | 3.09699917 |
| 47 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.08086844 |
| 48 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.04266395 |
| 49 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.03611794 |
| 50 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.00890459 |
| 51 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.95729632 |
| 52 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.95729632 |
| 53 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.95729632 |
| 54 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.94232557 |
| 55 | NADH dehydrogenase complex assembly (GO:0010257) | 2.94232557 |
| 56 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.94232557 |
| 57 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.91883071 |
| 58 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.91883071 |
| 59 | positive regulation of defense response to virus by host (GO:0002230) | 2.90526833 |
| 60 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.90486702 |
| 61 | ubiquinone biosynthetic process (GO:0006744) | 2.87367694 |
| 62 | cellular component biogenesis (GO:0044085) | 2.87333907 |
| 63 | base-excision repair, AP site formation (GO:0006285) | 2.86733100 |
| 64 | hydrogen ion transmembrane transport (GO:1902600) | 2.84373468 |
| 65 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.83594534 |
| 66 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.82268900 |
| 67 | negative regulation of T cell apoptotic process (GO:0070233) | 2.81259162 |
| 68 | actin nucleation (GO:0045010) | 2.80504601 |
| 69 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.79721245 |
| 70 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.78631300 |
| 71 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.78631300 |
| 72 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.77720469 |
| 73 | proton transport (GO:0015992) | 2.76013560 |
| 74 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 2.75743251 |
| 75 | negative regulation of ligase activity (GO:0051352) | 2.75743251 |
| 76 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.75386565 |
| 77 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.74860155 |
| 78 | ATP biosynthetic process (GO:0006754) | 2.73894884 |
| 79 | pseudouridine synthesis (GO:0001522) | 2.73476360 |
| 80 | positive T cell selection (GO:0043368) | 2.72740954 |
| 81 | hydrogen transport (GO:0006818) | 2.70367109 |
| 82 | protein complex disassembly (GO:0043241) | 2.68869697 |
| 83 | respiratory chain complex IV assembly (GO:0008535) | 2.68026214 |
| 84 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.67860634 |
| 85 | positive thymic T cell selection (GO:0045059) | 2.67280626 |
| 86 | rRNA processing (GO:0006364) | 2.66226248 |
| 87 | termination of RNA polymerase III transcription (GO:0006386) | 2.66157917 |
| 88 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.66157917 |
| 89 | rRNA metabolic process (GO:0016072) | 2.65783145 |
| 90 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 2.64860660 |
| 91 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.64743080 |
| 92 | regulation of chronic inflammatory response (GO:0002676) | 2.64177629 |
| 93 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.61881169 |
| 94 | ubiquinone metabolic process (GO:0006743) | 2.61508420 |
| 95 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.60706780 |
| 96 | macromolecular complex disassembly (GO:0032984) | 2.59401193 |
| 97 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.58286802 |
| 98 | protein targeting to membrane (GO:0006612) | 2.57978313 |
| 99 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.55191437 |
| 100 | protein-cofactor linkage (GO:0018065) | 2.55045765 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.96748222 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.72882350 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.62440684 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.50564990 |
| 5 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.49303322 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.30734352 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.22080402 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.92325574 |
| 9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.84504261 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.60944532 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.57011886 |
| 12 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.55466857 |
| 13 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.43238538 |
| 14 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.28119597 |
| 15 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.25794389 |
| 16 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.23954777 |
| 17 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.19243930 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.17279642 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.08856154 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.06972912 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.93084806 |
| 22 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.90768672 |
| 23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.88581610 |
| 24 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.87166879 |
| 25 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 1.87049381 |
| 26 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.82077501 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.69760121 |
| 28 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.65916255 |
| 29 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.65592900 |
| 30 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.62394473 |
| 31 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.61750460 |
| 32 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.57548591 |
| 33 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.53651365 |
| 34 | EWS_26573619_Chip-Seq_HEK293_Human | 1.51613707 |
| 35 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.50519436 |
| 36 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.49711633 |
| 37 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.48314460 |
| 38 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.47802820 |
| 39 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.46803623 |
| 40 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45997158 |
| 41 | MYB_26560356_Chip-Seq_TH2_Human | 1.44839680 |
| 42 | AR_20517297_ChIP-Seq_VCAP_Human | 1.38642034 |
| 43 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.35439958 |
| 44 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.35439958 |
| 45 | GATA3_26560356_Chip-Seq_TH2_Human | 1.35422063 |
| 46 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.33776662 |
| 47 | NCOR_22424771_ChIP-Seq_293T_Human | 1.32947344 |
| 48 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.26347635 |
| 49 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.24994465 |
| 50 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.22792723 |
| 51 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.21100337 |
| 52 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.20409738 |
| 53 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.20081355 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.18912996 |
| 55 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.17517186 |
| 56 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.16745735 |
| 57 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16338716 |
| 58 | FUS_26573619_Chip-Seq_HEK293_Human | 1.15896698 |
| 59 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.15835881 |
| 60 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14929552 |
| 61 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.13286712 |
| 62 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.13258602 |
| 63 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.12560125 |
| 64 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.12534009 |
| 65 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12508995 |
| 66 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.11666209 |
| 67 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.11606427 |
| 68 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.11218549 |
| 69 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.10281217 |
| 70 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.10061846 |
| 71 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.09935568 |
| 72 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.09541205 |
| 73 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.08042131 |
| 74 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.07922772 |
| 75 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.07219219 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05629131 |
| 77 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.05258925 |
| 78 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.04990251 |
| 79 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.04907867 |
| 80 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.04110347 |
| 81 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.04110347 |
| 82 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.04070626 |
| 83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.04070626 |
| 84 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.03280347 |
| 85 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.02248743 |
| 86 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.01855796 |
| 87 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.99186636 |
| 88 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.99085049 |
| 89 | XRN2_22483619_ChIP-Seq_HELA_Human | 0.98009745 |
| 90 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97790532 |
| 91 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.95644267 |
| 92 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95256679 |
| 93 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.95157133 |
| 94 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.91794544 |
| 95 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.91711838 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.91634277 |
| 97 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.90999952 |
| 98 | ERA_21632823_ChIP-Seq_H3396_Human | 0.90344147 |
| 99 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.89995932 |
| 100 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.88182176 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 4.47118836 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.77305865 |
| 3 | MP0001835_abnormal_antigen_presentation | 2.80209235 |
| 4 | MP0004147_increased_porphyrin_level | 2.74842702 |
| 5 | MP0009785_altered_susceptibility_to | 2.41775144 |
| 6 | MP0002102_abnormal_ear_morphology | 2.11023468 |
| 7 | MP0006292_abnormal_olfactory_placode | 2.01848034 |
| 8 | MP0008872_abnormal_physiological_respon | 2.00890052 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 1.98742087 |
| 10 | MP0003763_abnormal_thymus_physiology | 1.98468546 |
| 11 | MP0009333_abnormal_splenocyte_physiolog | 1.90269396 |
| 12 | MP0002138_abnormal_hepatobiliary_system | 1.88471891 |
| 13 | MP0001800_abnormal_humoral_immune | 1.84980155 |
| 14 | MP0008877_abnormal_DNA_methylation | 1.84276256 |
| 15 | MP0005075_abnormal_melanosome_morpholog | 1.83357089 |
| 16 | MP0002163_abnormal_gland_morphology | 1.80946188 |
| 17 | MP0003806_abnormal_nucleotide_metabolis | 1.80624044 |
| 18 | MP0005000_abnormal_immune_tolerance | 1.80033902 |
| 19 | MP0000685_abnormal_immune_system | 1.77073624 |
| 20 | MP0005084_abnormal_gallbladder_morpholo | 1.76761393 |
| 21 | MP0005645_abnormal_hypothalamus_physiol | 1.73038058 |
| 22 | MP0003646_muscle_fatigue | 1.66887161 |
| 23 | MP0002148_abnormal_hypersensitivity_rea | 1.66750206 |
| 24 | MP0004145_abnormal_muscle_electrophysio | 1.64000760 |
| 25 | MP0000372_irregular_coat_pigmentation | 1.61682768 |
| 26 | MP0003866_abnormal_defecation | 1.56187649 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.56164760 |
| 28 | MP0002723_abnormal_immune_serum | 1.55058911 |
| 29 | MP0001968_abnormal_touch/_nociception | 1.54786010 |
| 30 | MP0001873_stomach_inflammation | 1.53721670 |
| 31 | MP0008875_abnormal_xenobiotic_pharmacok | 1.53283770 |
| 32 | MP0005377_hearing/vestibular/ear_phenot | 1.52403881 |
| 33 | MP0003878_abnormal_ear_physiology | 1.52403881 |
| 34 | MP0001529_abnormal_vocalization | 1.52272741 |
| 35 | MP0005389_reproductive_system_phenotype | 1.50193196 |
| 36 | MP0002653_abnormal_ependyma_morphology | 1.50029889 |
| 37 | MP0002420_abnormal_adaptive_immunity | 1.49734810 |
| 38 | MP0001819_abnormal_immune_cell | 1.45129361 |
| 39 | MP0005551_abnormal_eye_electrophysiolog | 1.44517553 |
| 40 | MP0001986_abnormal_taste_sensitivity | 1.39823870 |
| 41 | MP0008058_abnormal_DNA_repair | 1.38455255 |
| 42 | MP0002160_abnormal_reproductive_system | 1.38105332 |
| 43 | MP0005025_abnormal_response_to | 1.36569712 |
| 44 | MP0004885_abnormal_endolymph | 1.36255031 |
| 45 | MP0001919_abnormal_reproductive_system | 1.35228009 |
| 46 | MP0002736_abnormal_nociception_after | 1.34929745 |
| 47 | MP0004142_abnormal_muscle_tone | 1.33887568 |
| 48 | MP0005387_immune_system_phenotype | 1.33590510 |
| 49 | MP0001790_abnormal_immune_system | 1.33590510 |
| 50 | MP0005379_endocrine/exocrine_gland_phen | 1.32778402 |
| 51 | MP0002006_tumorigenesis | 1.28987224 |
| 52 | MP0003786_premature_aging | 1.26999144 |
| 53 | MP0002166_altered_tumor_susceptibility | 1.21973849 |
| 54 | MP0002398_abnormal_bone_marrow | 1.19659144 |
| 55 | MP0002452_abnormal_antigen_presenting | 1.19456287 |
| 56 | MP0000716_abnormal_immune_system | 1.15325452 |
| 57 | MP0002405_respiratory_system_inflammati | 1.14452458 |
| 58 | MP0002876_abnormal_thyroid_physiology | 1.14095161 |
| 59 | MP0001485_abnormal_pinna_reflex | 1.13559993 |
| 60 | MP0005646_abnormal_pituitary_gland | 1.13125766 |
| 61 | MP0006036_abnormal_mitochondrial_physio | 1.10200896 |
| 62 | MP0002095_abnormal_skin_pigmentation | 1.09446434 |
| 63 | MP0010155_abnormal_intestine_physiology | 1.08923935 |
| 64 | MP0001764_abnormal_homeostasis | 1.08711949 |
| 65 | MP0002277_abnormal_respiratory_mucosa | 1.07721421 |
| 66 | MP0001905_abnormal_dopamine_level | 1.06880550 |
| 67 | MP0000703_abnormal_thymus_morphology | 1.06778104 |
| 68 | MP0003011_delayed_dark_adaptation | 1.05980719 |
| 69 | MP0000689_abnormal_spleen_morphology | 1.03836342 |
| 70 | MP0002272_abnormal_nervous_system | 1.03415679 |
| 71 | MP0006276_abnormal_autonomic_nervous | 1.02061182 |
| 72 | MP0003195_calcinosis | 1.00778057 |
| 73 | MP0005253_abnormal_eye_physiology | 1.00520482 |
| 74 | MP0009764_decreased_sensitivity_to | 0.98692441 |
| 75 | MP0001542_abnormal_bone_strength | 0.98140561 |
| 76 | MP0001501_abnormal_sleep_pattern | 0.97628574 |
| 77 | MP0008995_early_reproductive_senescence | 0.97199101 |
| 78 | MP0002722_abnormal_immune_system | 0.95597932 |
| 79 | MP0001845_abnormal_inflammatory_respons | 0.92675607 |
| 80 | MP0005410_abnormal_fertilization | 0.91442773 |
| 81 | MP0003186_abnormal_redox_activity | 0.90671601 |
| 82 | MP0002429_abnormal_blood_cell | 0.88613803 |
| 83 | MP0003787_abnormal_imprinting | 0.87114865 |
| 84 | MP0004742_abnormal_vestibular_system | 0.84139518 |
| 85 | MP0003718_maternal_effect | 0.83350138 |
| 86 | MP0002638_abnormal_pupillary_reflex | 0.83012820 |
| 87 | MP0002234_abnormal_pharynx_morphology | 0.82824961 |
| 88 | MP0005636_abnormal_mineral_homeostasis | 0.81403265 |
| 89 | MP0002693_abnormal_pancreas_physiology | 0.80758205 |
| 90 | MP0008789_abnormal_olfactory_epithelium | 0.78785249 |
| 91 | MP0008469_abnormal_protein_level | 0.77678256 |
| 92 | MP0003567_abnormal_fetal_cardiomyocyte | 0.76868802 |
| 93 | MP0005332_abnormal_amino_acid | 0.76151769 |
| 94 | MP0005174_abnormal_tail_pigmentation | 0.74911235 |
| 95 | MP0003724_increased_susceptibility_to | 0.74615767 |
| 96 | MP0009745_abnormal_behavioral_response | 0.74375145 |
| 97 | MP0006082_CNS_inflammation | 0.72257366 |
| 98 | MP0000631_abnormal_neuroendocrine_gland | 0.67156740 |
| 99 | MP0001663_abnormal_digestive_system | 0.65731766 |
| 100 | MP0002733_abnormal_thermal_nociception | 0.64833439 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 3.98982184 |
| 2 | Mitochondrial inheritance (HP:0001427) | 3.94953962 |
| 3 | Aplastic anemia (HP:0001915) | 3.86186638 |
| 4 | IgG deficiency (HP:0004315) | 3.79014193 |
| 5 | Congenital stationary night blindness (HP:0007642) | 3.63531837 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.58569852 |
| 7 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.55953581 |
| 8 | Molar tooth sign on MRI (HP:0002419) | 3.49183665 |
| 9 | Abnormality of midbrain morphology (HP:0002418) | 3.49183665 |
| 10 | Increased CSF lactate (HP:0002490) | 3.47063939 |
| 11 | Pancreatic cysts (HP:0001737) | 3.44513001 |
| 12 | Acute encephalopathy (HP:0006846) | 3.40648961 |
| 13 | Severe combined immunodeficiency (HP:0004430) | 3.39408703 |
| 14 | Increased hepatocellular lipid droplets (HP:0006565) | 3.38022965 |
| 15 | Hepatocellular necrosis (HP:0001404) | 3.36401508 |
| 16 | Abnormality of B cell number (HP:0010975) | 3.23095260 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.21590640 |
| 18 | Increased IgM level (HP:0003496) | 3.20473215 |
| 19 | Reticulocytopenia (HP:0001896) | 3.19770430 |
| 20 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.15509181 |
| 21 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.12820921 |
| 22 | 3-Methylglutaconic aciduria (HP:0003535) | 3.12159543 |
| 23 | Hepatic necrosis (HP:0002605) | 3.11108589 |
| 24 | Hypoproteinemia (HP:0003075) | 3.08094001 |
| 25 | Lipid accumulation in hepatocytes (HP:0006561) | 3.07369007 |
| 26 | True hermaphroditism (HP:0010459) | 3.04946587 |
| 27 | Increased intramyocellular lipid droplets (HP:0012240) | 3.03861321 |
| 28 | Pancreatic fibrosis (HP:0100732) | 3.03854577 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.89013202 |
| 30 | Cerebral edema (HP:0002181) | 2.85050577 |
| 31 | Stomatitis (HP:0010280) | 2.84645778 |
| 32 | B lymphocytopenia (HP:0010976) | 2.77168120 |
| 33 | Renal Fanconi syndrome (HP:0001994) | 2.77065907 |
| 34 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.72608119 |
| 35 | Thyroiditis (HP:0100646) | 2.70491365 |
| 36 | Abolished electroretinogram (ERG) (HP:0000550) | 2.65678082 |
| 37 | Abnormality of the renal cortex (HP:0011035) | 2.65606614 |
| 38 | Macrocytic anemia (HP:0001972) | 2.62532376 |
| 39 | Increased serum lactate (HP:0002151) | 2.60155891 |
| 40 | Abnormality of T cell number (HP:0011839) | 2.59857160 |
| 41 | Type II lissencephaly (HP:0007260) | 2.56660792 |
| 42 | Optic disc pallor (HP:0000543) | 2.55905160 |
| 43 | T lymphocytopenia (HP:0005403) | 2.53567922 |
| 44 | Combined immunodeficiency (HP:0005387) | 2.49159104 |
| 45 | Increased muscle lipid content (HP:0009058) | 2.48090252 |
| 46 | Renal cortical cysts (HP:0000803) | 2.44421873 |
| 47 | Abnormality of T cells (HP:0002843) | 2.44124966 |
| 48 | Abnormality of the prostate (HP:0008775) | 2.43628522 |
| 49 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.43335005 |
| 50 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.43335005 |
| 51 | Nephronophthisis (HP:0000090) | 2.41042798 |
| 52 | Lactic acidosis (HP:0003128) | 2.36883445 |
| 53 | Hyperglycinemia (HP:0002154) | 2.32876867 |
| 54 | Methylmalonic acidemia (HP:0002912) | 2.32225678 |
| 55 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.27881586 |
| 56 | Exertional dyspnea (HP:0002875) | 2.21100438 |
| 57 | Lethargy (HP:0001254) | 2.17661742 |
| 58 | Pancytopenia (HP:0001876) | 2.16157793 |
| 59 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.16134971 |
| 60 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.15763194 |
| 61 | Encephalitis (HP:0002383) | 2.15697105 |
| 62 | Congenital, generalized hypertrichosis (HP:0004540) | 2.14141991 |
| 63 | Panhypogammaglobulinemia (HP:0003139) | 2.09832232 |
| 64 | Medial flaring of the eyebrow (HP:0010747) | 2.09818660 |
| 65 | Autoimmune hemolytic anemia (HP:0001890) | 2.09717084 |
| 66 | Constricted visual fields (HP:0001133) | 2.09703615 |
| 67 | Stenosis of the external auditory canal (HP:0000402) | 2.07599534 |
| 68 | Glycosuria (HP:0003076) | 2.06017143 |
| 69 | Abnormality of urine glucose concentration (HP:0011016) | 2.06017143 |
| 70 | Prostate neoplasm (HP:0100787) | 2.05883425 |
| 71 | Abnormality of eosinophils (HP:0001879) | 2.03771866 |
| 72 | Methylmalonic aciduria (HP:0012120) | 2.03426048 |
| 73 | Abnormality of the renal medulla (HP:0100957) | 2.02862994 |
| 74 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.02087941 |
| 75 | Abnormality of alanine metabolism (HP:0010916) | 2.02087941 |
| 76 | Hyperalaninemia (HP:0003348) | 2.02087941 |
| 77 | Ketosis (HP:0001946) | 2.01899568 |
| 78 | Pallor (HP:0000980) | 2.00044524 |
| 79 | Cystic liver disease (HP:0006706) | 2.00034571 |
| 80 | Type 2 muscle fiber atrophy (HP:0003554) | 1.98732726 |
| 81 | Sclerocornea (HP:0000647) | 1.94708477 |
| 82 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 1.94560953 |
| 83 | Respiratory failure (HP:0002878) | 1.93871593 |
| 84 | Abnormality of T cell physiology (HP:0011840) | 1.93759752 |
| 85 | Colon cancer (HP:0003003) | 1.93381103 |
| 86 | Abnormal drinking behavior (HP:0030082) | 1.92644097 |
| 87 | Polydipsia (HP:0001959) | 1.92644097 |
| 88 | Cerebellar dysplasia (HP:0007033) | 1.92152422 |
| 89 | Stomach cancer (HP:0012126) | 1.91710318 |
| 90 | Tubular atrophy (HP:0000092) | 1.90130477 |
| 91 | Asplenia (HP:0001746) | 1.88955500 |
| 92 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.88000042 |
| 93 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.87959022 |
| 94 | Abnormality of glycine metabolism (HP:0010895) | 1.87959022 |
| 95 | Leukodystrophy (HP:0002415) | 1.83935230 |
| 96 | Attenuation of retinal blood vessels (HP:0007843) | 1.82793426 |
| 97 | Pendular nystagmus (HP:0012043) | 1.82622127 |
| 98 | Abnormality of renal resorption (HP:0011038) | 1.80774727 |
| 99 | Muscle fiber atrophy (HP:0100295) | 1.80067462 |
| 100 | Respiratory difficulties (HP:0002880) | 1.79262970 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.54522682 |
| 2 | KDR | 3.42758452 |
| 3 | BCKDK | 3.18560439 |
| 4 | VRK2 | 3.06319859 |
| 5 | ZAK | 2.97430732 |
| 6 | MAP4K2 | 2.81476936 |
| 7 | ADRBK2 | 2.52993103 |
| 8 | TAOK3 | 2.47121982 |
| 9 | TLK1 | 2.31952824 |
| 10 | GRK1 | 2.17475149 |
| 11 | NUAK1 | 2.12564374 |
| 12 | PASK | 2.09885286 |
| 13 | WNK4 | 2.06684822 |
| 14 | PINK1 | 1.95102623 |
| 15 | VRK1 | 1.93120341 |
| 16 | CDK19 | 1.93024090 |
| 17 | MAP4K1 | 1.91340853 |
| 18 | TESK2 | 1.71136658 |
| 19 | MAP3K12 | 1.64793263 |
| 20 | EIF2AK3 | 1.64758569 |
| 21 | ITK | 1.60838062 |
| 22 | NME1 | 1.57277905 |
| 23 | SYK | 1.43452137 |
| 24 | GRK6 | 1.30651655 |
| 25 | MUSK | 1.28837326 |
| 26 | MST4 | 1.25378529 |
| 27 | TEC | 1.24011549 |
| 28 | DYRK2 | 1.22725079 |
| 29 | MAP2K6 | 1.22092715 |
| 30 | STK16 | 1.21168498 |
| 31 | WNK3 | 1.17818541 |
| 32 | SCYL2 | 1.16252239 |
| 33 | FRK | 1.15314572 |
| 34 | BMPR1B | 1.13446394 |
| 35 | TIE1 | 1.10382849 |
| 36 | FES | 1.10297540 |
| 37 | LIMK1 | 1.08375433 |
| 38 | INSRR | 1.06695910 |
| 39 | BUB1 | 1.05280128 |
| 40 | PRKCQ | 1.03746936 |
| 41 | BTK | 0.99036165 |
| 42 | IKBKB | 0.96972192 |
| 43 | LCK | 0.94454149 |
| 44 | KIT | 0.94249596 |
| 45 | STK39 | 0.93156373 |
| 46 | CAMKK2 | 0.91736040 |
| 47 | OXSR1 | 0.89545316 |
| 48 | TRIM28 | 0.89497449 |
| 49 | PBK | 0.81905187 |
| 50 | CSF1R | 0.80450746 |
| 51 | DAPK1 | 0.79448843 |
| 52 | LYN | 0.76357776 |
| 53 | TAF1 | 0.75287849 |
| 54 | GRK7 | 0.73612327 |
| 55 | RPS6KA4 | 0.71728043 |
| 56 | RPS6KA5 | 0.70547636 |
| 57 | CSK | 0.63765304 |
| 58 | MAP3K11 | 0.63576842 |
| 59 | BMPR2 | 0.62280403 |
| 60 | ZAP70 | 0.61758944 |
| 61 | ADRBK1 | 0.61722554 |
| 62 | PIK3CG | 0.58673359 |
| 63 | IKBKE | 0.55857943 |
| 64 | FLT3 | 0.54320630 |
| 65 | MYLK | 0.53756847 |
| 66 | IGF1R | 0.52984429 |
| 67 | SRPK1 | 0.51110174 |
| 68 | PIM1 | 0.49873288 |
| 69 | CSNK2A2 | 0.47797291 |
| 70 | CSNK1G3 | 0.47489542 |
| 71 | MAPKAPK3 | 0.47021453 |
| 72 | DAPK3 | 0.46709453 |
| 73 | CAMKK1 | 0.46038222 |
| 74 | PIK3CA | 0.45934066 |
| 75 | OBSCN | 0.44639837 |
| 76 | PRKCE | 0.44106102 |
| 77 | MAPK13 | 0.43582424 |
| 78 | CSNK2A1 | 0.43534022 |
| 79 | PLK3 | 0.43385782 |
| 80 | PRKACA | 0.41931556 |
| 81 | PRKCA | 0.40817110 |
| 82 | PLK4 | 0.40770728 |
| 83 | TSSK6 | 0.40734291 |
| 84 | ATR | 0.38606213 |
| 85 | EIF2AK2 | 0.38275277 |
| 86 | MAP3K4 | 0.38092021 |
| 87 | AURKB | 0.38061569 |
| 88 | PRKCG | 0.35295480 |
| 89 | NEK1 | 0.34330552 |
| 90 | CSNK1G1 | 0.32715528 |
| 91 | PRKCH | 0.32470222 |
| 92 | PHKG2 | 0.31832402 |
| 93 | PHKG1 | 0.31832402 |
| 94 | CSNK1G2 | 0.31694686 |
| 95 | HCK | 0.31677495 |
| 96 | AURKA | 0.30848087 |
| 97 | JAK3 | 0.29810337 |
| 98 | MAP3K5 | 0.28588684 |
| 99 | RPS6KA6 | 0.28316768 |
| 100 | DAPK2 | 0.27015179 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 4.24448938 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.01788531 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.65611119 |
| 4 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.64368406 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.97313612 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.60516296 |
| 7 | Allograft rejection_Homo sapiens_hsa05330 | 2.43247756 |
| 8 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.37512861 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.26004028 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.24532329 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.15351908 |
| 12 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.09712148 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.00900222 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.95720236 |
| 15 | Alzheimers disease_Homo sapiens_hsa05010 | 1.90950058 |
| 16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.79628717 |
| 17 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.79096915 |
| 18 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.75054896 |
| 19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.70765403 |
| 20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.68553865 |
| 21 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.65485231 |
| 22 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.64529004 |
| 23 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.63199733 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.61845567 |
| 25 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.59897155 |
| 26 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.58082316 |
| 27 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.50693180 |
| 28 | Phototransduction_Homo sapiens_hsa04744 | 1.49408326 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.26610268 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.25486671 |
| 31 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.23550472 |
| 32 | Homologous recombination_Homo sapiens_hsa03440 | 1.23349008 |
| 33 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.19285117 |
| 34 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.17168802 |
| 35 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12586682 |
| 36 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.10282960 |
| 37 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.10192564 |
| 38 | Basal transcription factors_Homo sapiens_hsa03022 | 1.09814077 |
| 39 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.08248937 |
| 40 | Peroxisome_Homo sapiens_hsa04146 | 1.02498979 |
| 41 | Purine metabolism_Homo sapiens_hsa00230 | 1.00101305 |
| 42 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.96179274 |
| 43 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.95640251 |
| 44 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.92313124 |
| 45 | Spliceosome_Homo sapiens_hsa03040 | 0.91336085 |
| 46 | RNA transport_Homo sapiens_hsa03013 | 0.88368756 |
| 47 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79994880 |
| 48 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.77808313 |
| 49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.77797035 |
| 50 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.76906795 |
| 51 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74185083 |
| 52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.71788444 |
| 53 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.71723216 |
| 54 | Base excision repair_Homo sapiens_hsa03410 | 0.71671094 |
| 55 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.70768285 |
| 56 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.70300519 |
| 57 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.68685840 |
| 58 | Viral myocarditis_Homo sapiens_hsa05416 | 0.67424436 |
| 59 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.67014933 |
| 60 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.66508076 |
| 61 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.65056560 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.64800326 |
| 63 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.64794567 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63582293 |
| 65 | Metabolic pathways_Homo sapiens_hsa01100 | 0.60937460 |
| 66 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.60781272 |
| 67 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.60757588 |
| 68 | DNA replication_Homo sapiens_hsa03030 | 0.60608091 |
| 69 | Mismatch repair_Homo sapiens_hsa03430 | 0.56837089 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.55701688 |
| 71 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.55294170 |
| 72 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.52368882 |
| 73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52162263 |
| 74 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.51058577 |
| 75 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.50781821 |
| 76 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.50756803 |
| 77 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.50663156 |
| 78 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.49030315 |
| 79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45990128 |
| 80 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.43077785 |
| 81 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.41120366 |
| 82 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.39696595 |
| 83 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.37619538 |
| 84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.36810291 |
| 85 | Measles_Homo sapiens_hsa05162 | 0.36625992 |
| 86 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.35482723 |
| 87 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.33506359 |
| 88 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.33349222 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.32632717 |
| 90 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.28521849 |
| 91 | Nicotine addiction_Homo sapiens_hsa05033 | 0.28403414 |
| 92 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.27235763 |
| 93 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.26897322 |
| 94 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.25333083 |
| 95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.24950340 |
| 96 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.24857849 |
| 97 | Shigellosis_Homo sapiens_hsa05131 | 0.21072761 |
| 98 | Taste transduction_Homo sapiens_hsa04742 | 0.20868741 |
| 99 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.20564016 |
| 100 | Malaria_Homo sapiens_hsa05144 | 0.20448880 |

