Rank | Gene Set | Z-score |
---|---|---|
1 | ribosomal small subunit assembly (GO:0000028) | 6.64249337 |
2 | viral transcription (GO:0019083) | 6.43594616 |
3 | translational termination (GO:0006415) | 6.19291435 |
4 | maturation of SSU-rRNA (GO:0030490) | 6.07712774 |
5 | ribosomal small subunit biogenesis (GO:0042274) | 5.85051609 |
6 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.55433422 |
7 | translational elongation (GO:0006414) | 5.33764980 |
8 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.32201947 |
9 | cotranslational protein targeting to membrane (GO:0006613) | 5.26665306 |
10 | protein targeting to ER (GO:0045047) | 5.21759471 |
11 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.01718792 |
12 | protein localization to endoplasmic reticulum (GO:0070972) | 4.92172442 |
13 | viral life cycle (GO:0019058) | 4.66447898 |
14 | cellular protein complex disassembly (GO:0043624) | 4.60948251 |
15 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.46395218 |
16 | ribosomal large subunit biogenesis (GO:0042273) | 4.44269940 |
17 | behavioral response to nicotine (GO:0035095) | 4.28381894 |
18 | translational initiation (GO:0006413) | 4.17016315 |
19 | DNA deamination (GO:0045006) | 3.91935510 |
20 | protein neddylation (GO:0045116) | 3.89584362 |
21 | maturation of 5.8S rRNA (GO:0000460) | 3.83426610 |
22 | protein complex disassembly (GO:0043241) | 3.82651045 |
23 | macromolecular complex disassembly (GO:0032984) | 3.62476482 |
24 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.55689033 |
25 | cell proliferation in forebrain (GO:0021846) | 3.54084124 |
26 | termination of RNA polymerase III transcription (GO:0006386) | 3.46194747 |
27 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.46194747 |
28 | translation (GO:0006412) | 3.45319597 |
29 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.43951957 |
30 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.43951957 |
31 | protein targeting to membrane (GO:0006612) | 3.41444199 |
32 | forebrain morphogenesis (GO:0048853) | 3.35582943 |
33 | cellular component biogenesis (GO:0044085) | 3.28686999 |
34 | protein-cofactor linkage (GO:0018065) | 3.25879775 |
35 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.22158241 |
36 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.21542758 |
37 | rRNA catabolic process (GO:0016075) | 3.15717846 |
38 | axoneme assembly (GO:0035082) | 3.12036144 |
39 | interferon-gamma production (GO:0032609) | 3.11441334 |
40 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.10898475 |
41 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.10887268 |
42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.10887268 |
43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.10887268 |
44 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.09558350 |
45 | GTP biosynthetic process (GO:0006183) | 3.07442511 |
46 | mRNA catabolic process (GO:0006402) | 3.05559217 |
47 | rRNA processing (GO:0006364) | 3.05278441 |
48 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.04377210 |
49 | rRNA metabolic process (GO:0016072) | 3.02895957 |
50 | ATP synthesis coupled proton transport (GO:0015986) | 3.02841039 |
51 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.02841039 |
52 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 2.98087086 |
53 | neuron fate determination (GO:0048664) | 2.97665155 |
54 | ubiquinone biosynthetic process (GO:0006744) | 2.95612913 |
55 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.94993815 |
56 | protein complex biogenesis (GO:0070271) | 2.91987118 |
57 | ubiquinone metabolic process (GO:0006743) | 2.91725568 |
58 | negative regulation of telomere maintenance (GO:0032205) | 2.90874885 |
59 | chaperone-mediated protein transport (GO:0072321) | 2.90086981 |
60 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.87853533 |
61 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 2.86326265 |
62 | response to pheromone (GO:0019236) | 2.85763058 |
63 | somite development (GO:0061053) | 2.85705384 |
64 | piRNA metabolic process (GO:0034587) | 2.76573679 |
65 | intraciliary transport (GO:0042073) | 2.76072987 |
66 | epithelial cilium movement (GO:0003351) | 2.73639814 |
67 | glycerophospholipid catabolic process (GO:0046475) | 2.69966965 |
68 | RNA catabolic process (GO:0006401) | 2.69822151 |
69 | response to nitrosative stress (GO:0051409) | 2.69268997 |
70 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.66126488 |
71 | telencephalon development (GO:0021537) | 2.63957217 |
72 | regulation of cilium movement (GO:0003352) | 2.62641635 |
73 | pyrimidine nucleotide catabolic process (GO:0006244) | 2.61899581 |
74 | positive regulation of T cell apoptotic process (GO:0070234) | 2.61706246 |
75 | L-fucose catabolic process (GO:0042355) | 2.61480067 |
76 | fucose catabolic process (GO:0019317) | 2.61480067 |
77 | L-fucose metabolic process (GO:0042354) | 2.61480067 |
78 | olfactory bulb development (GO:0021772) | 2.61238411 |
79 | vitamin biosynthetic process (GO:0009110) | 2.61149370 |
80 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.60850810 |
81 | platelet dense granule organization (GO:0060155) | 2.59210334 |
82 | nephron tubule morphogenesis (GO:0072078) | 2.55378835 |
83 | nephron epithelium morphogenesis (GO:0072088) | 2.55378835 |
84 | aldehyde catabolic process (GO:0046185) | 2.52649758 |
85 | positive regulation of protein homooligomerization (GO:0032464) | 2.52419917 |
86 | nonmotile primary cilium assembly (GO:0035058) | 2.51374740 |
87 | protein polyglutamylation (GO:0018095) | 2.50904241 |
88 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.50175445 |
89 | UTP biosynthetic process (GO:0006228) | 2.50071917 |
90 | regulation of chronic inflammatory response (GO:0002676) | 2.48520705 |
91 | photoreceptor cell maintenance (GO:0045494) | 2.47108813 |
92 | ribosome biogenesis (GO:0042254) | 2.46295417 |
93 | regulation of energy homeostasis (GO:2000505) | 2.45121908 |
94 | spinal cord association neuron differentiation (GO:0021527) | 2.45083653 |
95 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.44781136 |
96 | pattern specification involved in kidney development (GO:0061004) | 2.44706601 |
97 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.43660462 |
98 | detection of light stimulus involved in visual perception (GO:0050908) | 2.43660462 |
99 | cardiovascular system development (GO:0072358) | 2.42166134 |
100 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.41990900 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.15000035 |
2 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.75697392 |
3 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.61712033 |
4 | VDR_22108803_ChIP-Seq_LS180_Human | 3.30646471 |
5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.11626234 |
6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.09363542 |
7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 3.01069366 |
8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.75406347 |
9 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.46465654 |
10 | EWS_26573619_Chip-Seq_HEK293_Human | 2.13769033 |
11 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.09790684 |
12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.98349525 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.96805381 |
14 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.96098214 |
15 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.86552739 |
16 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.81267065 |
17 | FUS_26573619_Chip-Seq_HEK293_Human | 1.80951772 |
18 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.80428804 |
19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.79119566 |
20 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.77217382 |
21 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.70556327 |
22 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.69740965 |
23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.68957208 |
24 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.68927484 |
25 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.67701062 |
26 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.62106180 |
27 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.59629020 |
28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.59387200 |
29 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.56847946 |
30 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.56483722 |
31 | P300_19829295_ChIP-Seq_ESCs_Human | 1.54303009 |
32 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.51508945 |
33 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.51404264 |
34 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.49022796 |
35 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.46400851 |
36 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.41827411 |
37 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.38055630 |
38 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.35714190 |
39 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.35714190 |
40 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.34112598 |
41 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.33233805 |
42 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.31774424 |
43 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.30344581 |
44 | NCOR_22424771_ChIP-Seq_293T_Human | 1.29715025 |
45 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.28452737 |
46 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.27394780 |
47 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.27241747 |
48 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.26614295 |
49 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.26335970 |
50 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.25121931 |
51 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.24418109 |
52 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.24418109 |
53 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.23813740 |
54 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.23257025 |
55 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.21746798 |
56 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21256185 |
57 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.20529679 |
58 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.18223900 |
59 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.18109003 |
60 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.16993283 |
61 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.16892670 |
62 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.16681534 |
63 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.15547546 |
64 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.13334317 |
65 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.13210758 |
66 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.11464176 |
67 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.10678309 |
68 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.09026973 |
69 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.05792151 |
70 | AR_20517297_ChIP-Seq_VCAP_Human | 1.04288503 |
71 | ERA_21632823_ChIP-Seq_H3396_Human | 1.02764608 |
72 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.02193654 |
73 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.02193654 |
74 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.01088361 |
75 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.01074937 |
76 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.00217033 |
77 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.99446338 |
78 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.99206029 |
79 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.97650596 |
80 | HOXB7_26014856_ChIP-Seq_BT474_Human | 0.97609190 |
81 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.96436017 |
82 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95749467 |
83 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 0.95538480 |
84 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 0.94700234 |
85 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.94692543 |
86 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94511861 |
87 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.91630816 |
88 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 0.89632788 |
89 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89148490 |
90 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.89086520 |
91 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.89063928 |
92 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.88887917 |
93 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.87980609 |
94 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.87578240 |
95 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.86809228 |
96 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.86410733 |
97 | STAT3_23295773_ChIP-Seq_U87_Human | 0.86000372 |
98 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.85711428 |
99 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.85431567 |
100 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.85307574 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002653_abnormal_ependyma_morphology | 3.87676380 |
2 | MP0006292_abnormal_olfactory_placode | 3.66974318 |
3 | MP0008877_abnormal_DNA_methylation | 3.21450345 |
4 | MP0009379_abnormal_foot_pigmentation | 2.98551164 |
5 | MP0003787_abnormal_imprinting | 2.61278910 |
6 | MP0002102_abnormal_ear_morphology | 2.52940313 |
7 | MP0003122_maternal_imprinting | 2.48515458 |
8 | MP0002163_abnormal_gland_morphology | 2.38281087 |
9 | MP0002138_abnormal_hepatobiliary_system | 2.33733921 |
10 | MP0004142_abnormal_muscle_tone | 2.31520396 |
11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.13600641 |
12 | MP0002876_abnormal_thyroid_physiology | 2.13324147 |
13 | MP0002837_dystrophic_cardiac_calcinosis | 2.11988547 |
14 | MP0005084_abnormal_gallbladder_morpholo | 2.09258032 |
15 | MP0006276_abnormal_autonomic_nervous | 2.07412070 |
16 | MP0004145_abnormal_muscle_electrophysio | 2.02246191 |
17 | MP0004885_abnormal_endolymph | 1.94008958 |
18 | MP0003121_genomic_imprinting | 1.93286996 |
19 | MP0006072_abnormal_retinal_apoptosis | 1.88315267 |
20 | MP0001984_abnormal_olfaction | 1.86959615 |
21 | MP0005377_hearing/vestibular/ear_phenot | 1.82772662 |
22 | MP0003878_abnormal_ear_physiology | 1.82772662 |
23 | MP0005551_abnormal_eye_electrophysiolog | 1.78843949 |
24 | MP0001348_abnormal_lacrimal_gland | 1.73761418 |
25 | MP0003646_muscle_fatigue | 1.72050405 |
26 | MP0006054_spinal_hemorrhage | 1.64645334 |
27 | MP0008789_abnormal_olfactory_epithelium | 1.60338350 |
28 | MP0004742_abnormal_vestibular_system | 1.59105466 |
29 | MP0008872_abnormal_physiological_respon | 1.58257003 |
30 | MP0005645_abnormal_hypothalamus_physiol | 1.55595993 |
31 | MP0003123_paternal_imprinting | 1.54270389 |
32 | MP0000049_abnormal_middle_ear | 1.53715932 |
33 | MP0001968_abnormal_touch/_nociception | 1.48270427 |
34 | MP0001986_abnormal_taste_sensitivity | 1.43504313 |
35 | MP0002272_abnormal_nervous_system | 1.42881100 |
36 | MP0005389_reproductive_system_phenotype | 1.37769544 |
37 | MP0005379_endocrine/exocrine_gland_phen | 1.34168551 |
38 | MP0003880_abnormal_central_pattern | 1.32443193 |
39 | MP0000778_abnormal_nervous_system | 1.31239309 |
40 | MP0001873_stomach_inflammation | 1.30638566 |
41 | MP0002234_abnormal_pharynx_morphology | 1.28591501 |
42 | MP0002938_white_spotting | 1.28201059 |
43 | MP0001485_abnormal_pinna_reflex | 1.27211718 |
44 | MP0001188_hyperpigmentation | 1.22910418 |
45 | MP0005499_abnormal_olfactory_system | 1.22112722 |
46 | MP0005394_taste/olfaction_phenotype | 1.22112722 |
47 | MP0000631_abnormal_neuroendocrine_gland | 1.19482461 |
48 | MP0003186_abnormal_redox_activity | 1.18234370 |
49 | MP0002736_abnormal_nociception_after | 1.17588669 |
50 | MP0001501_abnormal_sleep_pattern | 1.17382951 |
51 | MP0001293_anophthalmia | 1.16286744 |
52 | MP0002160_abnormal_reproductive_system | 1.15938676 |
53 | MP0001919_abnormal_reproductive_system | 1.13845500 |
54 | MP0003693_abnormal_embryo_hatching | 1.10388731 |
55 | MP0004084_abnormal_cardiac_muscle | 1.09194041 |
56 | MP0002928_abnormal_bile_duct | 1.08203808 |
57 | MP0002638_abnormal_pupillary_reflex | 1.07238257 |
58 | MP0005646_abnormal_pituitary_gland | 1.04728982 |
59 | MP0009745_abnormal_behavioral_response | 1.04708335 |
60 | MP0000026_abnormal_inner_ear | 1.04206796 |
61 | MP0005253_abnormal_eye_physiology | 1.03644667 |
62 | MP0005195_abnormal_posterior_eye | 1.02277150 |
63 | MP0001529_abnormal_vocalization | 1.01997904 |
64 | MP0002184_abnormal_innervation | 1.01592171 |
65 | MP0003567_abnormal_fetal_cardiomyocyte | 1.01310217 |
66 | MP0008995_early_reproductive_senescence | 1.00629193 |
67 | MP0002557_abnormal_social/conspecific_i | 1.00049040 |
68 | MP0004133_heterotaxia | 0.99060216 |
69 | MP0009046_muscle_twitch | 0.97726397 |
70 | MP0008775_abnormal_heart_ventricle | 0.96375470 |
71 | MP0002572_abnormal_emotion/affect_behav | 0.94867181 |
72 | MP0002277_abnormal_respiratory_mucosa | 0.94804791 |
73 | MP0002693_abnormal_pancreas_physiology | 0.93958252 |
74 | MP0001764_abnormal_homeostasis | 0.92671897 |
75 | MP0001286_abnormal_eye_development | 0.91993736 |
76 | MP0003937_abnormal_limbs/digits/tail_de | 0.91507750 |
77 | MP0000372_irregular_coat_pigmentation | 0.89464858 |
78 | MP0001970_abnormal_pain_threshold | 0.88320302 |
79 | MP0001905_abnormal_dopamine_level | 0.88169693 |
80 | MP0002733_abnormal_thermal_nociception | 0.87100020 |
81 | MP0002095_abnormal_skin_pigmentation | 0.86932156 |
82 | MP0001944_abnormal_pancreas_morphology | 0.86375426 |
83 | MP0002752_abnormal_somatic_nervous | 0.86097683 |
84 | MP0005174_abnormal_tail_pigmentation | 0.84814770 |
85 | MP0003890_abnormal_embryonic-extraembry | 0.84255903 |
86 | MP0005448_abnormal_energy_balance | 0.83946168 |
87 | MP0000427_abnormal_hair_cycle | 0.83858520 |
88 | MP0000685_abnormal_immune_system | 0.82407692 |
89 | MP0009764_decreased_sensitivity_to | 0.81547520 |
90 | MP0008058_abnormal_DNA_repair | 0.80540481 |
91 | MP0002751_abnormal_autonomic_nervous | 0.76428428 |
92 | MP0003195_calcinosis | 0.76016409 |
93 | MP0003283_abnormal_digestive_organ | 0.75824435 |
94 | MP0001963_abnormal_hearing_physiology | 0.75411465 |
95 | MP0002210_abnormal_sex_determination | 0.75041360 |
96 | MP0009250_abnormal_appendicular_skeleto | 0.74447422 |
97 | MP0005220_abnormal_exocrine_pancreas | 0.73759143 |
98 | MP0001486_abnormal_startle_reflex | 0.73291331 |
99 | MP0003252_abnormal_bile_duct | 0.72179682 |
100 | MP0001440_abnormal_grooming_behavior | 0.71487573 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Reticulocytopenia (HP:0001896) | 4.41578912 |
2 | Chronic hepatic failure (HP:0100626) | 4.21200916 |
3 | Acute necrotizing encephalopathy (HP:0006965) | 4.15244678 |
4 | Pancreatic fibrosis (HP:0100732) | 3.82685758 |
5 | Molar tooth sign on MRI (HP:0002419) | 3.63509237 |
6 | Abnormality of midbrain morphology (HP:0002418) | 3.63509237 |
7 | Acute encephalopathy (HP:0006846) | 3.57377905 |
8 | Pancreatic cysts (HP:0001737) | 3.49370462 |
9 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.45622767 |
10 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.45252101 |
11 | Progressive macrocephaly (HP:0004481) | 3.37970847 |
12 | Congenital stationary night blindness (HP:0007642) | 3.23046330 |
13 | Mitochondrial inheritance (HP:0001427) | 3.17578752 |
14 | True hermaphroditism (HP:0010459) | 3.14699592 |
15 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.09009839 |
16 | Macrocytic anemia (HP:0001972) | 3.02642286 |
17 | Stomatitis (HP:0010280) | 2.95609742 |
18 | Increased CSF lactate (HP:0002490) | 2.91567548 |
19 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.89572115 |
20 | Absent/shortened dynein arms (HP:0200106) | 2.89572115 |
21 | Nephronophthisis (HP:0000090) | 2.85808637 |
22 | Optic disc pallor (HP:0000543) | 2.73483399 |
23 | Abolished electroretinogram (ERG) (HP:0000550) | 2.63590727 |
24 | Medial flaring of the eyebrow (HP:0010747) | 2.62733799 |
25 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.59885291 |
26 | Cerebral edema (HP:0002181) | 2.58589358 |
27 | Type II lissencephaly (HP:0007260) | 2.57956353 |
28 | Septo-optic dysplasia (HP:0100842) | 2.57592564 |
29 | Increased hepatocellular lipid droplets (HP:0006565) | 2.53658257 |
30 | Constricted visual fields (HP:0001133) | 2.53604727 |
31 | Abnormal number of erythroid precursors (HP:0012131) | 2.50181419 |
32 | Abnormality of the renal medulla (HP:0100957) | 2.49711260 |
33 | Abnormality of the labia minora (HP:0012880) | 2.45299047 |
34 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.44283854 |
35 | Cystic liver disease (HP:0006706) | 2.43726842 |
36 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.40992166 |
37 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.40992166 |
38 | Abnormality of the renal cortex (HP:0011035) | 2.38608854 |
39 | Methylmalonic acidemia (HP:0002912) | 2.37524177 |
40 | Hypoplasia of the pons (HP:0012110) | 2.35950348 |
41 | Asplenia (HP:0001746) | 2.34534137 |
42 | Renal Fanconi syndrome (HP:0001994) | 2.32939045 |
43 | Lipid accumulation in hepatocytes (HP:0006561) | 2.32903282 |
44 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.31412090 |
45 | Pallor (HP:0000980) | 2.29503335 |
46 | Sclerocornea (HP:0000647) | 2.27374421 |
47 | Hypoplasia of the uterus (HP:0000013) | 2.21459508 |
48 | Hyperglycinemia (HP:0002154) | 2.20522497 |
49 | Abnormality of the pons (HP:0007361) | 2.20067179 |
50 | Cerebellar dysplasia (HP:0007033) | 2.19839375 |
51 | Increased serum lactate (HP:0002151) | 2.19459894 |
52 | Stenosis of the external auditory canal (HP:0000402) | 2.17398641 |
53 | Postaxial foot polydactyly (HP:0001830) | 2.15451777 |
54 | Attenuation of retinal blood vessels (HP:0007843) | 2.14705001 |
55 | Hepatocellular necrosis (HP:0001404) | 2.13580228 |
56 | Pendular nystagmus (HP:0012043) | 2.12534975 |
57 | Abnormal drinking behavior (HP:0030082) | 2.10675921 |
58 | Polydipsia (HP:0001959) | 2.10675921 |
59 | Decreased central vision (HP:0007663) | 2.09306570 |
60 | Abnormal hemoglobin (HP:0011902) | 2.06969316 |
61 | Abnormal ciliary motility (HP:0012262) | 2.06008774 |
62 | Polyuria (HP:0000103) | 2.04051888 |
63 | Abnormality of alanine metabolism (HP:0010916) | 2.03446284 |
64 | Hyperalaninemia (HP:0003348) | 2.03446284 |
65 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.03446284 |
66 | Gait imbalance (HP:0002141) | 2.01480337 |
67 | Tubular atrophy (HP:0000092) | 2.00825921 |
68 | Anencephaly (HP:0002323) | 1.98276359 |
69 | Polyphagia (HP:0002591) | 1.97560070 |
70 | Congenital primary aphakia (HP:0007707) | 1.97240596 |
71 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.96199605 |
72 | Absent thumb (HP:0009777) | 1.94867031 |
73 | Male pseudohermaphroditism (HP:0000037) | 1.93306598 |
74 | Leukodystrophy (HP:0002415) | 1.92105489 |
75 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.91210753 |
76 | Hepatic necrosis (HP:0002605) | 1.88953532 |
77 | Rib fusion (HP:0000902) | 1.87234701 |
78 | Nephrogenic diabetes insipidus (HP:0009806) | 1.85958777 |
79 | Congenital hepatic fibrosis (HP:0002612) | 1.84317289 |
80 | Triphalangeal thumb (HP:0001199) | 1.83548041 |
81 | Inability to walk (HP:0002540) | 1.83216966 |
82 | Depressed nasal ridge (HP:0000457) | 1.80972471 |
83 | Methylmalonic aciduria (HP:0012120) | 1.80936346 |
84 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.80397456 |
85 | Lethargy (HP:0001254) | 1.80258745 |
86 | Abnormality of DNA repair (HP:0003254) | 1.79362123 |
87 | Glycosuria (HP:0003076) | 1.79190700 |
88 | Abnormality of urine glucose concentration (HP:0011016) | 1.79190700 |
89 | Optic nerve hypoplasia (HP:0000609) | 1.78427236 |
90 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.76977837 |
91 | Growth hormone deficiency (HP:0000824) | 1.76003881 |
92 | Narrow forehead (HP:0000341) | 1.75148348 |
93 | Retinitis pigmentosa (HP:0000510) | 1.75040970 |
94 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.73847906 |
95 | Abnormality of renal resorption (HP:0011038) | 1.73691902 |
96 | Type 2 muscle fiber atrophy (HP:0003554) | 1.72493991 |
97 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.72406343 |
98 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.72232053 |
99 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.72071684 |
100 | Elevated erythrocyte sedimentation rate (HP:0003565) | 1.67673556 |
Rank | Gene Set | Z-score |
---|---|---|
1 | PASK | 4.36710295 |
2 | PINK1 | 3.57160853 |
3 | WNK4 | 3.19416584 |
4 | MAP4K2 | 2.65710798 |
5 | FRK | 2.57301400 |
6 | TXK | 2.52557796 |
7 | ADRBK2 | 2.45785749 |
8 | CAMKK1 | 2.29740957 |
9 | BCKDK | 2.16519126 |
10 | NUAK1 | 2.10457079 |
11 | CDK19 | 2.09892008 |
12 | ZAK | 2.04510980 |
13 | NLK | 2.03130913 |
14 | GRK1 | 1.89225395 |
15 | DYRK2 | 1.83348044 |
16 | WNK3 | 1.82464800 |
17 | CAMKK2 | 1.78178899 |
18 | STK39 | 1.72291296 |
19 | TIE1 | 1.53574451 |
20 | TNIK | 1.45827679 |
21 | MAP4K1 | 1.44243496 |
22 | PBK | 1.40394170 |
23 | EPHB2 | 1.28935997 |
24 | MKNK2 | 1.26806756 |
25 | STK16 | 1.23818652 |
26 | CSNK1G1 | 1.16575225 |
27 | OXSR1 | 1.15487408 |
28 | PIK3CA | 1.12795946 |
29 | TLK1 | 1.10614163 |
30 | BMPR1B | 1.09889762 |
31 | CDK3 | 1.07781673 |
32 | VRK1 | 1.06912274 |
33 | SGK223 | 1.06478101 |
34 | SGK494 | 1.06478101 |
35 | PRKCQ | 1.03937355 |
36 | LRRK2 | 1.02609331 |
37 | TRIM28 | 0.96835838 |
38 | VRK2 | 0.93719301 |
39 | PRKCG | 0.93118337 |
40 | SGK2 | 0.92280466 |
41 | MST4 | 0.91233083 |
42 | MAPK13 | 0.90592427 |
43 | BCR | 0.88709249 |
44 | NME1 | 0.84817899 |
45 | PRKD3 | 0.84039744 |
46 | MKNK1 | 0.83255900 |
47 | CAMK1 | 0.82789510 |
48 | BUB1 | 0.80409798 |
49 | IKBKB | 0.78838157 |
50 | PAK3 | 0.78612060 |
51 | TAOK3 | 0.78466316 |
52 | TEC | 0.73788038 |
53 | RPS6KA4 | 0.71548324 |
54 | EIF2AK3 | 0.71537723 |
55 | INSRR | 0.70331723 |
56 | PLK3 | 0.69863819 |
57 | PRKCE | 0.66745631 |
58 | BRSK2 | 0.66278960 |
59 | SYK | 0.65584733 |
60 | TSSK6 | 0.61571765 |
61 | ITK | 0.60226153 |
62 | NEK2 | 0.59172344 |
63 | RPS6KA5 | 0.57212795 |
64 | CSNK1G2 | 0.56285409 |
65 | ADRBK1 | 0.56030349 |
66 | PAK6 | 0.55570158 |
67 | NTRK2 | 0.55263912 |
68 | CSNK1G3 | 0.54615067 |
69 | CDC7 | 0.54262490 |
70 | DYRK1A | 0.53816393 |
71 | TYRO3 | 0.53771942 |
72 | CASK | 0.53378965 |
73 | BTK | 0.50992924 |
74 | IKBKE | 0.50741513 |
75 | MARK3 | 0.50152925 |
76 | PLK1 | 0.49630370 |
77 | OBSCN | 0.48399225 |
78 | TGFBR1 | 0.47975394 |
79 | MAP2K6 | 0.47854619 |
80 | PLK4 | 0.47154659 |
81 | DAPK2 | 0.47104023 |
82 | TAF1 | 0.46625918 |
83 | PRKCI | 0.45578759 |
84 | STK11 | 0.45572876 |
85 | PRKACA | 0.45432878 |
86 | KIT | 0.45306978 |
87 | CSNK2A2 | 0.44331984 |
88 | CSNK1A1 | 0.43794367 |
89 | WNK1 | 0.43715528 |
90 | PRKCZ | 0.43194117 |
91 | PRKCH | 0.41580745 |
92 | PRKCD | 0.41283853 |
93 | PAK1 | 0.40935135 |
94 | PRKG1 | 0.40415490 |
95 | CSNK1A1L | 0.39800198 |
96 | PRKCA | 0.39538138 |
97 | RPS6KA6 | 0.39069910 |
98 | CAMK2A | 0.37317857 |
99 | PIK3CG | 0.37014677 |
100 | AURKA | 0.36516692 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ribosome_Homo sapiens_hsa03010 | 5.61897231 |
2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.01629079 |
3 | RNA polymerase_Homo sapiens_hsa03020 | 2.67973889 |
4 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.39907625 |
5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.37928507 |
6 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.18829721 |
7 | Proteasome_Homo sapiens_hsa03050 | 2.18103486 |
8 | Asthma_Homo sapiens_hsa05310 | 2.17987306 |
9 | Phototransduction_Homo sapiens_hsa04744 | 2.05765138 |
10 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.00326170 |
11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.95896014 |
12 | Basal transcription factors_Homo sapiens_hsa03022 | 1.93642808 |
13 | Protein export_Homo sapiens_hsa03060 | 1.90617876 |
14 | RNA degradation_Homo sapiens_hsa03018 | 1.82895414 |
15 | Allograft rejection_Homo sapiens_hsa05330 | 1.79084553 |
16 | Huntingtons disease_Homo sapiens_hsa05016 | 1.71222487 |
17 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.70953752 |
18 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.70532335 |
19 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.67991868 |
20 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.67713261 |
21 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.66227998 |
22 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.63719950 |
23 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.63196157 |
24 | Alzheimers disease_Homo sapiens_hsa05010 | 1.59754026 |
25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57839506 |
26 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.50205961 |
27 | Homologous recombination_Homo sapiens_hsa03440 | 1.46898148 |
28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.46417662 |
29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.45063123 |
30 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.42261777 |
31 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.39789032 |
32 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.38902842 |
33 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.34699418 |
34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.34553687 |
35 | Nicotine addiction_Homo sapiens_hsa05033 | 1.23077808 |
36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.13596901 |
37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.12797843 |
38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.06090134 |
39 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.01680013 |
40 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.00525955 |
41 | Olfactory transduction_Homo sapiens_hsa04740 | 0.98298509 |
42 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.97743242 |
43 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.95883248 |
44 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.93447666 |
45 | Insulin secretion_Homo sapiens_hsa04911 | 0.89644880 |
46 | Purine metabolism_Homo sapiens_hsa00230 | 0.87813848 |
47 | Peroxisome_Homo sapiens_hsa04146 | 0.87492535 |
48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.86168897 |
49 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.83966442 |
50 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.83951884 |
51 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.83951757 |
52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.83390214 |
53 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.82740133 |
54 | Cocaine addiction_Homo sapiens_hsa05030 | 0.81333390 |
55 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.79933479 |
56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.75878112 |
57 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.75529758 |
58 | RNA transport_Homo sapiens_hsa03013 | 0.74202162 |
59 | Taste transduction_Homo sapiens_hsa04742 | 0.73998495 |
60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.73584042 |
61 | Morphine addiction_Homo sapiens_hsa05032 | 0.73303575 |
62 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.70839316 |
63 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.70362904 |
64 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.69422010 |
65 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.68630916 |
66 | Sulfur relay system_Homo sapiens_hsa04122 | 0.68516690 |
67 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.68283126 |
68 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.66768548 |
69 | Salivary secretion_Homo sapiens_hsa04970 | 0.66171635 |
70 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65753896 |
71 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64268317 |
72 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.63458977 |
73 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.62166170 |
74 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61610516 |
75 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.59775190 |
76 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.59047520 |
77 | Base excision repair_Homo sapiens_hsa03410 | 0.58881493 |
78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58579390 |
79 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.58155035 |
80 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.51833655 |
81 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51481636 |
82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.48743927 |
83 | Mismatch repair_Homo sapiens_hsa03430 | 0.47089854 |
84 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.46626090 |
85 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.46112345 |
86 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.45246751 |
87 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.43625814 |
88 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.43347473 |
89 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.38061974 |
90 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.36998952 |
91 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.36715829 |
92 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.34969105 |
93 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.34854552 |
94 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.34825550 |
95 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.33956433 |
96 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.25533943 |
97 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.25485766 |
98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.22320271 |
99 | Circadian rhythm_Homo sapiens_hsa04710 | 0.22319145 |
100 | Spliceosome_Homo sapiens_hsa03040 | 0.21608266 |