RPL5P12

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.44475521
2viral transcription (GO:0019083)6.05203374
3maturation of SSU-rRNA (GO:0030490)5.85072884
4translational termination (GO:0006415)5.82848935
5SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.15813135
6cotranslational protein targeting to membrane (GO:0006613)5.07383299
7translational elongation (GO:0006414)5.06145363
8protein targeting to ER (GO:0045047)5.02435648
9ribosomal small subunit biogenesis (GO:0042274)4.92998250
10establishment of protein localization to endoplasmic reticulum (GO:0072599)4.82313097
11protein localization to endoplasmic reticulum (GO:0070972)4.75255143
12water-soluble vitamin biosynthetic process (GO:0042364)4.68652605
13ribosomal large subunit biogenesis (GO:0042273)4.52900607
14viral life cycle (GO:0019058)4.37674961
15cellular protein complex disassembly (GO:0043624)4.27178795
16energy coupled proton transport, down electrochemical gradient (GO:0015985)4.26290048
17ATP synthesis coupled proton transport (GO:0015986)4.26290048
18DNA deamination (GO:0045006)4.19720838
19nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)4.18374125
20mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.15412707
21protein neddylation (GO:0045116)4.05832882
22translational initiation (GO:0006413)4.05812778
23response to pheromone (GO:0019236)4.00620933
24behavioral response to nicotine (GO:0035095)3.93481363
25mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.87546745
26establishment of protein localization to mitochondrial membrane (GO:0090151)3.66841294
27translation (GO:0006412)3.61365930
28protein complex biogenesis (GO:0070271)3.61025874
29ubiquinone biosynthetic process (GO:0006744)3.60648325
30protein complex disassembly (GO:0043241)3.50074775
31electron transport chain (GO:0022900)3.47906932
32respiratory electron transport chain (GO:0022904)3.46454761
33nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.40845372
34mitochondrial respiratory chain complex I assembly (GO:0032981)3.36412977
35NADH dehydrogenase complex assembly (GO:0010257)3.36412977
36mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.36412977
37macromolecular complex disassembly (GO:0032984)3.35521741
38cellular ketone body metabolic process (GO:0046950)3.34497342
39chaperone-mediated protein transport (GO:0072321)3.32735659
40ribonucleoprotein complex biogenesis (GO:0022613)3.30914159
41ubiquinone metabolic process (GO:0006743)3.29176990
42mitochondrial respiratory chain complex assembly (GO:0033108)3.28383964
43exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.27983882
44cellular component biogenesis (GO:0044085)3.27893031
45respiratory chain complex IV assembly (GO:0008535)3.27659772
46protein targeting to membrane (GO:0006612)3.27102708
47positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523)3.23975778
48L-fucose catabolic process (GO:0042355)3.22295693
49fucose catabolic process (GO:0019317)3.22295693
50L-fucose metabolic process (GO:0042354)3.22295693
51nuclear-transcribed mRNA catabolic process (GO:0000956)3.17422435
52RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.10472048
53tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.10472048
54GTP biosynthetic process (GO:0006183)3.09581719
55cytochrome complex assembly (GO:0017004)3.08956798
56regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522)3.01010354
57mRNA catabolic process (GO:0006402)3.00113408
58ketone body metabolic process (GO:1902224)2.97151211
59piRNA metabolic process (GO:0034587)2.95699159
60pseudouridine synthesis (GO:0001522)2.89183875
61negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.88636172
62regulation of isotype switching to IgG isotypes (GO:0048302)2.86895772
63aldehyde catabolic process (GO:0046185)2.86783288
64quinone biosynthetic process (GO:1901663)2.86315950
65base-excision repair, AP site formation (GO:0006285)2.85742511
66indolalkylamine metabolic process (GO:0006586)2.83902089
67rRNA metabolic process (GO:0016072)2.81171158
68rRNA processing (GO:0006364)2.80767819
69termination of RNA polymerase III transcription (GO:0006386)2.79237337
70transcription elongation from RNA polymerase III promoter (GO:0006385)2.79237337
71rRNA catabolic process (GO:0016075)2.78885918
72RNA catabolic process (GO:0006401)2.74634446
73interferon-gamma production (GO:0032609)2.73345089
74hydrogen ion transmembrane transport (GO:1902600)2.65870904
75protein polyglutamylation (GO:0018095)2.64447297
76proton transport (GO:0015992)2.63865489
77purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.63629202
78regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.62827790
79purine nucleoside triphosphate biosynthetic process (GO:0009145)2.61683892
80cell proliferation in forebrain (GO:0021846)2.61153913
81hydrogen transport (GO:0006818)2.59317406
82protein-cofactor linkage (GO:0018065)2.58353308
83UTP biosynthetic process (GO:0006228)2.57940884
84tRNA processing (GO:0008033)2.57649008
85maturation of 5.8S rRNA (GO:0000460)2.57566561
86kynurenine metabolic process (GO:0070189)2.51969250
87intracellular protein transmembrane import (GO:0044743)2.50490027
88regulation of regulatory T cell differentiation (GO:0045589)2.50297118
89ATP biosynthetic process (GO:0006754)2.49117881
90regulation of chronic inflammatory response (GO:0002676)2.48362621
91epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.45658243
92regulation of cellular respiration (GO:0043457)2.44076810
93negative regulation of telomere maintenance (GO:0032205)2.41937721
94detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.41793566
95RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.36739147
96vitamin biosynthetic process (GO:0009110)2.36509182
97detection of light stimulus involved in visual perception (GO:0050908)2.35472541
98detection of light stimulus involved in sensory perception (GO:0050962)2.35472541
99UTP metabolic process (GO:0046051)2.34030719
100regulation of action potential (GO:0098900)2.33974902

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.60102662
2GABP_17652178_ChIP-ChIP_JURKAT_Human3.60081931
3SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.04848634
4VDR_22108803_ChIP-Seq_LS180_Human2.97248920
5ZNF274_21170338_ChIP-Seq_K562_Hela2.95169286
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.91937195
7HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.91302034
8EST1_17652178_ChIP-ChIP_JURKAT_Human2.68108712
9FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.56381665
10ELF1_17652178_ChIP-ChIP_JURKAT_Human2.56092546
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.39974812
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.33829119
13VDR_23849224_ChIP-Seq_CD4+_Human2.09799444
14HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.05252162
15FLI1_27457419_Chip-Seq_LIVER_Mouse2.00490714
16MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.93750196
17EWS_26573619_Chip-Seq_HEK293_Human1.86856495
18CTBP1_25329375_ChIP-Seq_LNCAP_Human1.84451830
19MYC_18940864_ChIP-ChIP_HL60_Human1.75996503
20FUS_26573619_Chip-Seq_HEK293_Human1.74379559
21EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.70849626
22TP53_22573176_ChIP-Seq_HFKS_Human1.70176037
23IGF1R_20145208_ChIP-Seq_DFB_Human1.69213498
24FOXP3_21729870_ChIP-Seq_TREG_Human1.66903666
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.66833065
26ELK1_19687146_ChIP-ChIP_HELA_Human1.65139786
27NOTCH1_21737748_ChIP-Seq_TLL_Human1.65121418
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.61266244
29BMI1_23680149_ChIP-Seq_NPCS_Mouse1.60168132
30SRF_21415370_ChIP-Seq_HL-1_Mouse1.57133518
31PCGF2_27294783_Chip-Seq_ESCs_Mouse1.50413389
32GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.50143692
33GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.47671164
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.42922518
35MYC_18555785_ChIP-Seq_MESCs_Mouse1.41937809
36CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.41825592
37TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.40117161
38IRF1_19129219_ChIP-ChIP_H3396_Human1.38787236
39PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.34870002
40TTF2_22483619_ChIP-Seq_HELA_Human1.34053726
41AUTS2_25519132_ChIP-Seq_293T-REX_Human1.33972280
42FOXA1_25329375_ChIP-Seq_VCAP_Human1.33250855
43FOXA1_27270436_Chip-Seq_PROSTATE_Human1.33250855
44MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32244236
45IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.31132984
46CBP_20019798_ChIP-Seq_JUKART_Human1.31132984
47P300_19829295_ChIP-Seq_ESCs_Human1.30942532
48NCOR_22424771_ChIP-Seq_293T_Human1.26849652
49RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26739984
50AR_20517297_ChIP-Seq_VCAP_Human1.26403061
51ETV2_25802403_ChIP-Seq_MESCs_Mouse1.26154838
52PCGF2_27294783_Chip-Seq_NPCs_Mouse1.26054980
53REST_21632747_ChIP-Seq_MESCs_Mouse1.23445909
54FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.23380809
55CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.22398948
56NANOG_20526341_ChIP-Seq_ESCs_Human1.21336020
57CBX2_27304074_Chip-Seq_ESCs_Mouse1.20286213
58NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.20213201
59TAF15_26573619_Chip-Seq_HEK293_Human1.19984072
60ER_23166858_ChIP-Seq_MCF-7_Human1.19877889
61TAF2_19829295_ChIP-Seq_ESCs_Human1.18846286
62IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.18549003
63GATA3_21878914_ChIP-Seq_MCF-7_Human1.18003918
64CREB1_15753290_ChIP-ChIP_HEK293T_Human1.15124863
65YY1_21170310_ChIP-Seq_MESCs_Mouse1.14919397
66CTBP2_25329375_ChIP-Seq_LNCAP_Human1.14356585
67NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.11511432
68RNF2_27304074_Chip-Seq_NSC_Mouse1.09171328
69MYC_18358816_ChIP-ChIP_MESCs_Mouse1.07814636
70GBX2_23144817_ChIP-Seq_PC3_Human1.05709163
71EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.05545976
72EBNA1_20929547_Chip-Seq_RAJI-cells_Human1.05533236
73JARID2_20064375_ChIP-Seq_MESCs_Mouse1.05374846
74SOX2_19829295_ChIP-Seq_ESCs_Human1.04475525
75NANOG_19829295_ChIP-Seq_ESCs_Human1.04475525
76TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.02710424
77LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.02403706
78BCAT_22108803_ChIP-Seq_LS180_Human1.01843712
79MYC_19829295_ChIP-Seq_ESCs_Human1.01767493
80ERA_21632823_ChIP-Seq_H3396_Human1.01687146
81POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00410770
82TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00214283
83SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.99612094
84KLF5_20875108_ChIP-Seq_MESCs_Mouse0.99490916
85ERG_20517297_ChIP-Seq_VCAP_Human0.98009488
86RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.96948000
87HOXB7_26014856_ChIP-Seq_BT474_Human0.96541111
88GABP_19822575_ChIP-Seq_HepG2_Human0.96467178
89NFE2_27457419_Chip-Seq_LIVER_Mouse0.95965650
90FOXH1_21741376_ChIP-Seq_EPCs_Human0.95545348
91FOXA1_21572438_ChIP-Seq_LNCaP_Human0.93287049
92PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.92742569
93SUZ12_27294783_Chip-Seq_NPCs_Mouse0.92217757
94P53_21459846_ChIP-Seq_SAOS-2_Human0.92185605
95EZH2_27304074_Chip-Seq_ESCs_Mouse0.92124008
96UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91977160
97POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.91888443
98GATA3_26560356_Chip-Seq_TH2_Human0.89400139
99RBPJ_21746931_ChIP-Seq_IB4_Human0.88884600
100REST_18959480_ChIP-ChIP_MESCs_Mouse0.88373466

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0009379_abnormal_foot_pigmentation4.16207769
2MP0006292_abnormal_olfactory_placode3.42956261
3MP0002837_dystrophic_cardiac_calcinosis3.04604721
4MP0003787_abnormal_imprinting2.52555646
5MP0004142_abnormal_muscle_tone2.43419516
6MP0002163_abnormal_gland_morphology2.35118166
7MP0002102_abnormal_ear_morphology2.25658901
8MP0003646_muscle_fatigue2.24615208
9MP0008877_abnormal_DNA_methylation2.23091894
10MP0004885_abnormal_endolymph2.21657055
11MP0006276_abnormal_autonomic_nervous1.99795285
12MP0005671_abnormal_response_to1.99129124
13MP0002653_abnormal_ependyma_morphology1.96496935
14MP0001986_abnormal_taste_sensitivity1.92768740
15MP0005645_abnormal_hypothalamus_physiol1.92275262
16MP0005646_abnormal_pituitary_gland1.92235663
17MP0006072_abnormal_retinal_apoptosis1.92070209
18MP0005377_hearing/vestibular/ear_phenot1.85881859
19MP0003878_abnormal_ear_physiology1.85881859
20MP0008872_abnormal_physiological_respon1.84931238
21MP0005379_endocrine/exocrine_gland_phen1.75789399
22MP0003283_abnormal_digestive_organ1.74107642
23MP0004147_increased_porphyrin_level1.73783450
24MP0005075_abnormal_melanosome_morpholog1.73511069
25MP0005551_abnormal_eye_electrophysiolog1.73326712
26MP0004145_abnormal_muscle_electrophysio1.72999063
27MP0003122_maternal_imprinting1.62350819
28MP0002272_abnormal_nervous_system1.59436572
29MP0003195_calcinosis1.59370742
30MP0002138_abnormal_hepatobiliary_system1.53109775
31MP0001485_abnormal_pinna_reflex1.51119689
32MP0005084_abnormal_gallbladder_morpholo1.45303500
33MP0002876_abnormal_thyroid_physiology1.45088993
34MP0001501_abnormal_sleep_pattern1.41830542
35MP0000372_irregular_coat_pigmentation1.41577493
36MP0001968_abnormal_touch/_nociception1.38464951
37MP0005389_reproductive_system_phenotype1.36235057
38MP0003567_abnormal_fetal_cardiomyocyte1.35135696
39MP0008789_abnormal_olfactory_epithelium1.33282252
40MP0003121_genomic_imprinting1.31851170
41MP0002160_abnormal_reproductive_system1.25159940
42MP0003880_abnormal_central_pattern1.22754987
43MP0008875_abnormal_xenobiotic_pharmacok1.19580390
44MP0001919_abnormal_reproductive_system1.19006680
45MP0009046_muscle_twitch1.16891952
46MP0000631_abnormal_neuroendocrine_gland1.16663611
47MP0002638_abnormal_pupillary_reflex1.16255862
48MP0001188_hyperpigmentation1.16111742
49MP0005253_abnormal_eye_physiology1.15401539
50MP0003011_delayed_dark_adaptation1.13751234
51MP0002733_abnormal_thermal_nociception1.13651871
52MP0009745_abnormal_behavioral_response1.13284914
53MP0001873_stomach_inflammation1.12961548
54MP0002736_abnormal_nociception_after1.11157100
55MP0001529_abnormal_vocalization1.10760182
56MP0002693_abnormal_pancreas_physiology1.09362030
57MP0001984_abnormal_olfaction1.08381273
58MP0001440_abnormal_grooming_behavior1.07651882
59MP0002822_catalepsy1.07488380
60MP0001905_abnormal_dopamine_level1.06494964
61MP0004742_abnormal_vestibular_system1.06452342
62MP0001970_abnormal_pain_threshold1.06090368
63MP0003879_abnormal_hair_cell1.04471535
64MP0001835_abnormal_antigen_presentation1.04271713
65MP0002184_abnormal_innervation1.01790651
66MP0008058_abnormal_DNA_repair1.01436124
67MP0004043_abnormal_pH_regulation1.01115744
68MP0008775_abnormal_heart_ventricle0.98594772
69MP0005423_abnormal_somatic_nervous0.98506155
70MP0001486_abnormal_startle_reflex0.93397557
71MP0001293_anophthalmia0.93321105
72MP0000049_abnormal_middle_ear0.92155688
73MP0009785_altered_susceptibility_to0.90293891
74MP0003866_abnormal_defecation0.88909007
75MP0002572_abnormal_emotion/affect_behav0.88885642
76MP0006036_abnormal_mitochondrial_physio0.88321555
77MP0002234_abnormal_pharynx_morphology0.88263548
78MP0002557_abnormal_social/conspecific_i0.88224787
79MP0000230_abnormal_systemic_arterial0.88190730
80MP0005394_taste/olfaction_phenotype0.87641529
81MP0005499_abnormal_olfactory_system0.87641529
82MP0002095_abnormal_skin_pigmentation0.85298686
83MP0005636_abnormal_mineral_homeostasis0.84843238
84MP0003123_paternal_imprinting0.83780637
85MP0003186_abnormal_redox_activity0.83097858
86MP0010386_abnormal_urinary_bladder0.83090109
87MP0003252_abnormal_bile_duct0.82439520
88MP0001944_abnormal_pancreas_morphology0.82011683
89MP0001800_abnormal_humoral_immune0.81439639
90MP0001764_abnormal_homeostasis0.80777891
91MP0005410_abnormal_fertilization0.80278129
92MP0005448_abnormal_energy_balance0.79578539
93MP0005332_abnormal_amino_acid0.79576031
94MP0004133_heterotaxia0.78823098
95MP0003635_abnormal_synaptic_transmissio0.78318237
96MP0001963_abnormal_hearing_physiology0.77386028
97MP0003718_maternal_effect0.76808611
98MP0002277_abnormal_respiratory_mucosa0.75315534
99MP0005195_abnormal_posterior_eye0.74665723
100MP0009333_abnormal_splenocyte_physiolog0.74584919

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.27885683
2Reticulocytopenia (HP:0001896)4.16656909
3Mitochondrial inheritance (HP:0001427)4.03222329
4Abnormal mitochondria in muscle tissue (HP:0008316)3.65137933
5Increased CSF lactate (HP:0002490)3.63445415
6Hepatocellular necrosis (HP:0001404)3.60989755
7Congenital stationary night blindness (HP:0007642)3.59999954
8Acute encephalopathy (HP:0006846)3.59562807
9Progressive macrocephaly (HP:0004481)3.59334243
10Pancreatic cysts (HP:0001737)3.58839934
11Increased hepatocellular lipid droplets (HP:0006565)3.58637491
12Pancreatic fibrosis (HP:0100732)3.52791533
13Abnormality of midbrain morphology (HP:0002418)3.51616705
14Molar tooth sign on MRI (HP:0002419)3.51616705
15Hepatic necrosis (HP:0002605)3.48972399
16Abnormality of cells of the erythroid lineage (HP:0012130)3.44783734
17Lipid accumulation in hepatocytes (HP:0006561)3.39607506
18True hermaphroditism (HP:0010459)3.30219146
19Absent rod-and cone-mediated responses on ERG (HP:0007688)3.11815986
20Abnormal number of erythroid precursors (HP:0012131)3.09711213
21Macrocytic anemia (HP:0001972)3.09023479
22Nephronophthisis (HP:0000090)3.07313572
23Methylmalonic acidemia (HP:0002912)3.04704917
24Abnormal rod and cone electroretinograms (HP:0008323)2.93833861
25Dynein arm defect of respiratory motile cilia (HP:0012255)2.92206288
26Absent/shortened dynein arms (HP:0200106)2.92206288
27Optic disc pallor (HP:0000543)2.90312595
28Renal Fanconi syndrome (HP:0001994)2.88145863
29Cerebral edema (HP:0002181)2.75193521
30Elevated erythrocyte sedimentation rate (HP:0003565)2.64060742
31Sclerocornea (HP:0000647)2.62752134
32IgG deficiency (HP:0004315)2.60983794
33Medial flaring of the eyebrow (HP:0010747)2.55000537
34Chronic hepatic failure (HP:0100626)2.47467956
35Increased serum lactate (HP:0002151)2.47201774
36Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.43694957
37Type II lissencephaly (HP:0007260)2.42219357
38Methylmalonic aciduria (HP:0012120)2.41848205
39Abnormality of the renal medulla (HP:0100957)2.41068867
40Increased intramyocellular lipid droplets (HP:0012240)2.37621227
413-Methylglutaconic aciduria (HP:0003535)2.36221966
42Abnormality of the renal cortex (HP:0011035)2.35474265
43Attenuation of retinal blood vessels (HP:0007843)2.33244314
44Absent thumb (HP:0009777)2.30224188
45Aplasia/Hypoplasia of the spleen (HP:0010451)2.29384963
46Decreased central vision (HP:0007663)2.28967513
47Pendular nystagmus (HP:0012043)2.27358379
48Abnormal respiratory motile cilium morphology (HP:0005938)2.26412868
49Abnormal respiratory epithelium morphology (HP:0012253)2.26412868
50Abnormality of urine glucose concentration (HP:0011016)2.25737452
51Glycosuria (HP:0003076)2.25737452
52Stomatitis (HP:0010280)2.25570069
53Colon cancer (HP:0003003)2.24499305
54Exertional dyspnea (HP:0002875)2.23086058
55Asplenia (HP:0001746)2.22166599
56Cystic liver disease (HP:0006706)2.21949952
57Renal cortical cysts (HP:0000803)2.20152987
58Abnormal ciliary motility (HP:0012262)2.18877353
59Agitation (HP:0000713)2.18222465
60Lactic acidosis (HP:0003128)2.18188779
61Pallor (HP:0000980)2.17901068
62Abnormal drinking behavior (HP:0030082)2.15975881
63Polydipsia (HP:0001959)2.15975881
64Abnormality of renal resorption (HP:0011038)2.14555462
65Abolished electroretinogram (ERG) (HP:0000550)2.09871677
66Ketosis (HP:0001946)2.08365848
67Constricted visual fields (HP:0001133)2.07764988
68Abnormality of DNA repair (HP:0003254)2.05458163
69Decreased electroretinogram (ERG) amplitude (HP:0000654)2.03507670
70Gait imbalance (HP:0002141)1.99686286
71Hyperglycinemia (HP:0002154)1.99329084
72Abnormal hemoglobin (HP:0011902)1.99215725
73Increased muscle lipid content (HP:0009058)1.98990164
74Anencephaly (HP:0002323)1.98714066
75Abnormality of vitamin B metabolism (HP:0004340)1.95353377
76Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.95025783
77Lethargy (HP:0001254)1.94345487
78Respiratory failure (HP:0002878)1.94321184
79Congenital primary aphakia (HP:0007707)1.93379646
80Type 2 muscle fiber atrophy (HP:0003554)1.92749498
81Abnormality of the vitamin B12 metabolism (HP:0004341)1.92691717
82Aplastic anemia (HP:0001915)1.90176092
83Abnormality of the labia minora (HP:0012880)1.89558247
84Male pseudohermaphroditism (HP:0000037)1.89068009
85Dicarboxylic aciduria (HP:0003215)1.88042066
86Abnormality of dicarboxylic acid metabolism (HP:0010995)1.88042066
87Hypoplasia of the pons (HP:0012110)1.85763507
88Hyperphosphaturia (HP:0003109)1.84349190
89Leukodystrophy (HP:0002415)1.82958918
90Hypoproteinemia (HP:0003075)1.81262497
91Congenital hepatic fibrosis (HP:0002612)1.79311886
92Nephrogenic diabetes insipidus (HP:0009806)1.79192298
93Abnormality of the pons (HP:0007361)1.78838039
94Exercise intolerance (HP:0003546)1.78287329
95Keratoconus (HP:0000563)1.77270521
96Increased corneal curvature (HP:0100692)1.77270521
97Postaxial foot polydactyly (HP:0001830)1.76872471
98Aplasia/Hypoplasia of the tongue (HP:0010295)1.76187675
99Abnormal respiratory motile cilium physiology (HP:0012261)1.74972890
100Tachypnea (HP:0002789)1.74867570

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK4.15535655
2TXK4.13399738
3GRK12.93004712
4MAP4K22.72625049
5WNK42.71167382
6PINK12.68895195
7FRK2.68865547
8STK162.60323669
9ADRBK22.58490602
10BCKDK2.40466081
11TLK12.12256662
12NUAK12.11605486
13VRK21.98922318
14TAOK31.87443333
15ZAK1.80694673
16TIE11.75692822
17TEC1.64911976
18CDK191.62166011
19DYRK21.60070886
20STK391.52958446
21CAMKK11.47104741
22NME11.46038840
23ITK1.39731194
24MAP4K11.39273180
25MAP2K61.34489487
26WNK31.28465640
27OXSR11.27463605
28ACVR1B1.23138707
29INSRR1.19947814
30TAF11.16000897
31PHKG21.09068841
32PHKG11.09068841
33BMPR1B1.06784432
34VRK11.05281233
35CAMKK21.00498967
36SYK0.94485548
37MAP3K110.91427568
38PRKCQ0.90211746
39TRIM280.88674589
40PRKCG0.88005873
41MAPK130.85199542
42MAP3K40.84376416
43CSNK1G30.84055979
44DAPK20.80537991
45KIT0.78969658
46CSNK1G20.78467483
47MKNK20.76824134
48BTK0.75968086
49NEK10.75681782
50ADRBK10.74835848
51TNIK0.74483494
52SIK20.73124824
53PRKCH0.70544975
54IKBKB0.69684217
55KDR0.68921121
56IKBKE0.67840782
57RPS6KA50.65918520
58PIK3CA0.62997297
59CASK0.62969506
60PRKD30.62732912
61CSNK1G10.61704082
62LCK0.60917533
63MKNK10.59915589
64CAMK10.58388460
65MAP2K70.58258006
66PRKCE0.57801311
67FES0.57738870
68CSNK1A1L0.56799043
69TYRO30.55872435
70NME20.54758115
71PRKACA0.54341848
72TNK20.52968387
73TSSK60.52493640
74TGFBR10.51184785
75CSNK2A20.50893470
76MAP3K120.50020928
77OBSCN0.49592020
78PLK40.48624167
79DAPK30.48444456
80PAK30.46927532
81PRKCA0.46467278
82LYN0.46332115
83ERBB30.44812885
84JAK30.44221176
85CSNK1A10.43811285
86DAPK10.41782253
87PLK30.37960969
88CSNK2A10.37563137
89RPS6KA60.37395271
90PRKCD0.37060721
91LRRK20.36358454
92CAMK2A0.36226776
93GRK60.35577379
94RPS6KA40.34709295
95GRK70.34224725
96MAP2K20.33497188
97GRK50.33285483
98WNK10.32837787
99MUSK0.32223883
100IGF1R0.31913412

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.09879231
2Oxidative phosphorylation_Homo sapiens_hsa001903.72603158
3Parkinsons disease_Homo sapiens_hsa050122.90648540
4Proteasome_Homo sapiens_hsa030502.70102820
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.43004550
6Protein export_Homo sapiens_hsa030602.42891587
7RNA polymerase_Homo sapiens_hsa030202.20344851
8Asthma_Homo sapiens_hsa053102.06308796
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.02935719
10Linoleic acid metabolism_Homo sapiens_hsa005912.00584240
11Huntingtons disease_Homo sapiens_hsa050161.94963113
12Alzheimers disease_Homo sapiens_hsa050101.93072850
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.91083178
14Cardiac muscle contraction_Homo sapiens_hsa042601.83233566
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.83000527
16alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.81585675
17Phototransduction_Homo sapiens_hsa047441.81311060
18Homologous recombination_Homo sapiens_hsa034401.80746565
19Allograft rejection_Homo sapiens_hsa053301.77782491
20Type I diabetes mellitus_Homo sapiens_hsa049401.75888557
21Intestinal immune network for IgA production_Homo sapiens_hsa046721.72872439
22Primary immunodeficiency_Homo sapiens_hsa053401.72239935
23RNA degradation_Homo sapiens_hsa030181.67350090
24Autoimmune thyroid disease_Homo sapiens_hsa053201.66990872
25Butanoate metabolism_Homo sapiens_hsa006501.63995643
26Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.57138355
27Maturity onset diabetes of the young_Homo sapiens_hsa049501.53478370
28One carbon pool by folate_Homo sapiens_hsa006701.48143935
29Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.45314353
30Nitrogen metabolism_Homo sapiens_hsa009101.41080883
31Propanoate metabolism_Homo sapiens_hsa006401.39517198
32Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.33380925
33Graft-versus-host disease_Homo sapiens_hsa053321.31556348
34Basal transcription factors_Homo sapiens_hsa030221.27249442
35Tryptophan metabolism_Homo sapiens_hsa003801.26070312
36Fanconi anemia pathway_Homo sapiens_hsa034601.17670145
37Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.12849801
38Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.12635529
39Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.10412323
40Pyrimidine metabolism_Homo sapiens_hsa002401.09837899
41Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.08151254
42Peroxisome_Homo sapiens_hsa041461.07697399
43Nicotine addiction_Homo sapiens_hsa050331.02958436
44Ether lipid metabolism_Homo sapiens_hsa005651.01485932
45Arachidonic acid metabolism_Homo sapiens_hsa005900.97467659
46Olfactory transduction_Homo sapiens_hsa047400.94249319
47Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.90224804
48Purine metabolism_Homo sapiens_hsa002300.85586250
49Fat digestion and absorption_Homo sapiens_hsa049750.85151544
50Caffeine metabolism_Homo sapiens_hsa002320.84266994
51Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81353631
52Nucleotide excision repair_Homo sapiens_hsa034200.79222559
53RNA transport_Homo sapiens_hsa030130.78294894
54Rheumatoid arthritis_Homo sapiens_hsa053230.77801675
55Hematopoietic cell lineage_Homo sapiens_hsa046400.75318704
56Steroid hormone biosynthesis_Homo sapiens_hsa001400.75106098
57Taste transduction_Homo sapiens_hsa047420.74810315
58Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.70988653
59Collecting duct acid secretion_Homo sapiens_hsa049660.70791379
60Metabolic pathways_Homo sapiens_hsa011000.69846462
61Base excision repair_Homo sapiens_hsa034100.69401335
62Chemical carcinogenesis_Homo sapiens_hsa052040.68863940
63Retinol metabolism_Homo sapiens_hsa008300.68324317
64Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.64357712
65Cysteine and methionine metabolism_Homo sapiens_hsa002700.64047393
66Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.61540473
67Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.60840973
68Antigen processing and presentation_Homo sapiens_hsa046120.59596069
69Regulation of autophagy_Homo sapiens_hsa041400.59309771
70Steroid biosynthesis_Homo sapiens_hsa001000.57882487
71Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.56598984
72Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.56569857
73Primary bile acid biosynthesis_Homo sapiens_hsa001200.56208234
74Spliceosome_Homo sapiens_hsa030400.54545607
75Pentose and glucuronate interconversions_Homo sapiens_hsa000400.53979877
76beta-Alanine metabolism_Homo sapiens_hsa004100.53565242
77Insulin secretion_Homo sapiens_hsa049110.53469338
78Morphine addiction_Homo sapiens_hsa050320.53263136
79Serotonergic synapse_Homo sapiens_hsa047260.51396756
80Mismatch repair_Homo sapiens_hsa034300.48941554
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48414940
82Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.48277397
83Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47523038
84Sulfur relay system_Homo sapiens_hsa041220.45180923
85Selenocompound metabolism_Homo sapiens_hsa004500.44546679
86Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.43917623
87T cell receptor signaling pathway_Homo sapiens_hsa046600.42792646
88Sulfur metabolism_Homo sapiens_hsa009200.41824646
89Glycerolipid metabolism_Homo sapiens_hsa005610.41133283
90Salivary secretion_Homo sapiens_hsa049700.39969497
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36321040
92Ovarian steroidogenesis_Homo sapiens_hsa049130.32775840
93DNA replication_Homo sapiens_hsa030300.32315758
94GABAergic synapse_Homo sapiens_hsa047270.31659123
95Fatty acid degradation_Homo sapiens_hsa000710.31139643
96Vitamin B6 metabolism_Homo sapiens_hsa007500.30372686
97Circadian entrainment_Homo sapiens_hsa047130.28235880
98Drug metabolism - other enzymes_Homo sapiens_hsa009830.27325377
99Folate biosynthesis_Homo sapiens_hsa007900.26598877
100Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.26458937

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »