

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | water-soluble vitamin biosynthetic process (GO:0042364) | 5.33046706 |
| 2 | ribosomal large subunit biogenesis (GO:0042273) | 4.42400153 |
| 3 | behavioral response to nicotine (GO:0035095) | 4.30970757 |
| 4 | maturation of SSU-rRNA (GO:0030490) | 4.25874399 |
| 5 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 4.15512783 |
| 6 | protein neddylation (GO:0045116) | 4.14417029 |
| 7 | regulation of isotype switching to IgG isotypes (GO:0048302) | 4.13891319 |
| 8 | positive regulation of tyrosine phosphorylation of Stat5 protein (GO:0042523) | 3.99428261 |
| 9 | maturation of 5.8S rRNA (GO:0000460) | 3.87605470 |
| 10 | ATP synthesis coupled proton transport (GO:0015986) | 3.87214002 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.87214002 |
| 12 | DNA deamination (GO:0045006) | 3.81574311 |
| 13 | regulation of tyrosine phosphorylation of Stat5 protein (GO:0042522) | 3.81321405 |
| 14 | ribosomal small subunit assembly (GO:0000028) | 3.74697082 |
| 15 | cellular ketone body metabolic process (GO:0046950) | 3.72991362 |
| 16 | viral transcription (GO:0019083) | 3.72091068 |
| 17 | translational termination (GO:0006415) | 3.69611278 |
| 18 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.65405836 |
| 19 | termination of RNA polymerase III transcription (GO:0006386) | 3.65405836 |
| 20 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.60050136 |
| 21 | cullin deneddylation (GO:0010388) | 3.57626186 |
| 22 | GTP biosynthetic process (GO:0006183) | 3.56561206 |
| 23 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.55963263 |
| 24 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.48790501 |
| 25 | ketone body metabolic process (GO:1902224) | 3.43239216 |
| 26 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.41151707 |
| 27 | kidney morphogenesis (GO:0060993) | 3.36614674 |
| 28 | ubiquinone metabolic process (GO:0006743) | 3.36613848 |
| 29 | response to pheromone (GO:0019236) | 3.36530232 |
| 30 | regulation of immunoglobulin secretion (GO:0051023) | 3.30286873 |
| 31 | translational elongation (GO:0006414) | 3.28566481 |
| 32 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.27193506 |
| 33 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.27162336 |
| 34 | protein deneddylation (GO:0000338) | 3.26587573 |
| 35 | protein-cofactor linkage (GO:0018065) | 3.23292903 |
| 36 | cotranslational protein targeting to membrane (GO:0006613) | 3.22872763 |
| 37 | protein targeting to ER (GO:0045047) | 3.22383569 |
| 38 | short-chain fatty acid metabolic process (GO:0046459) | 3.21951441 |
| 39 | chaperone-mediated protein transport (GO:0072321) | 3.21609684 |
| 40 | protein complex biogenesis (GO:0070271) | 3.20103857 |
| 41 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.14908061 |
| 42 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.14908061 |
| 43 | NADH dehydrogenase complex assembly (GO:0010257) | 3.14908061 |
| 44 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.09040172 |
| 45 | protein localization to endoplasmic reticulum (GO:0070972) | 3.07898604 |
| 46 | cellular response to ATP (GO:0071318) | 3.06929748 |
| 47 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.03802437 |
| 48 | electron transport chain (GO:0022900) | 3.03079515 |
| 49 | ribosomal small subunit biogenesis (GO:0042274) | 2.99082862 |
| 50 | respiratory electron transport chain (GO:0022904) | 2.96641764 |
| 51 | UTP biosynthetic process (GO:0006228) | 2.93613956 |
| 52 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 2.91111580 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 2.91111580 |
| 54 | positive regulation of isotype switching (GO:0045830) | 2.89787725 |
| 55 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.89344519 |
| 56 | translation (GO:0006412) | 2.89311136 |
| 57 | tRNA processing (GO:0008033) | 2.89302257 |
| 58 | peptidyl-histidine modification (GO:0018202) | 2.84448875 |
| 59 | UTP metabolic process (GO:0046051) | 2.84397122 |
| 60 | positive regulation of DNA recombination (GO:0045911) | 2.84393854 |
| 61 | translational initiation (GO:0006413) | 2.78677692 |
| 62 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.71736147 |
| 63 | viral life cycle (GO:0019058) | 2.71655249 |
| 64 | regulation of action potential (GO:0098900) | 2.70393258 |
| 65 | negative regulation of telomere maintenance (GO:0032205) | 2.69244464 |
| 66 | rRNA modification (GO:0000154) | 2.68803655 |
| 67 | cellular component biogenesis (GO:0044085) | 2.68667016 |
| 68 | rRNA processing (GO:0006364) | 2.67450085 |
| 69 | chromatin remodeling at centromere (GO:0031055) | 2.66279877 |
| 70 | regulation of cellular amino acid metabolic process (GO:0006521) | 2.64333237 |
| 71 | rRNA metabolic process (GO:0016072) | 2.64191330 |
| 72 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.63620586 |
| 73 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.60548217 |
| 74 | fucose catabolic process (GO:0019317) | 2.60460471 |
| 75 | L-fucose metabolic process (GO:0042354) | 2.60460471 |
| 76 | L-fucose catabolic process (GO:0042355) | 2.60460471 |
| 77 | cellular protein complex disassembly (GO:0043624) | 2.60293628 |
| 78 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.59577967 |
| 79 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.59287977 |
| 80 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.58488747 |
| 81 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.58488747 |
| 82 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.58488747 |
| 83 | tRNA metabolic process (GO:0006399) | 2.56953240 |
| 84 | branched-chain amino acid catabolic process (GO:0009083) | 2.55457438 |
| 85 | indolalkylamine metabolic process (GO:0006586) | 2.53598644 |
| 86 | adaptation of signaling pathway (GO:0023058) | 2.53128443 |
| 87 | CTP metabolic process (GO:0046036) | 2.51939851 |
| 88 | CTP biosynthetic process (GO:0006241) | 2.51939851 |
| 89 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.51934162 |
| 90 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.51934162 |
| 91 | vitamin biosynthetic process (GO:0009110) | 2.51823497 |
| 92 | ubiquinone biosynthetic process (GO:0006744) | 2.51497828 |
| 93 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.51303285 |
| 94 | nonmotile primary cilium assembly (GO:0035058) | 2.49543961 |
| 95 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.49538108 |
| 96 | piRNA metabolic process (GO:0034587) | 2.49253093 |
| 97 | termination of RNA polymerase I transcription (GO:0006363) | 2.47136753 |
| 98 | base-excision repair, AP site formation (GO:0006285) | 2.46547341 |
| 99 | pseudouridine synthesis (GO:0001522) | 2.45581385 |
| 100 | isoprenoid biosynthetic process (GO:0008299) | 2.45035787 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.05401090 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.78087808 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.68618622 |
| 4 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.49062854 |
| 5 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.11588104 |
| 6 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.01529031 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.96825142 |
| 8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.94362459 |
| 9 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.83375742 |
| 10 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.78625367 |
| 11 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.53983878 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.42508559 |
| 13 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.41425280 |
| 14 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.34235973 |
| 15 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.14276647 |
| 16 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.14274786 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.14269752 |
| 18 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.08983521 |
| 19 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.04345106 |
| 20 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.96907631 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 1.90194331 |
| 22 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.76432989 |
| 23 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.75722200 |
| 24 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.72962916 |
| 25 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.70812211 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.67351818 |
| 27 | FUS_26573619_Chip-Seq_HEK293_Human | 1.63214825 |
| 28 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.62387830 |
| 29 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.58115740 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.54326553 |
| 31 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.53225261 |
| 32 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.48547281 |
| 33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.44909657 |
| 34 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.44562662 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.43617015 |
| 36 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.42234712 |
| 37 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.41400656 |
| 38 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.37987350 |
| 39 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.35140148 |
| 40 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.35117769 |
| 41 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.34245122 |
| 42 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.33920915 |
| 43 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.32876334 |
| 44 | P300_19829295_ChIP-Seq_ESCs_Human | 1.31610743 |
| 45 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.26563139 |
| 46 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.22462430 |
| 47 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.22407125 |
| 48 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.21963915 |
| 49 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.21756666 |
| 50 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.21169605 |
| 51 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.21036726 |
| 52 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.19369833 |
| 53 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18926714 |
| 54 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.18715969 |
| 55 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.17338374 |
| 56 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.14733658 |
| 57 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.13767947 |
| 58 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.13767947 |
| 59 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.08437736 |
| 60 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.08380007 |
| 61 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.08380007 |
| 62 | NCOR_22424771_ChIP-Seq_293T_Human | 1.07358104 |
| 63 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.06060115 |
| 64 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.05741742 |
| 65 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.05532358 |
| 66 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.05354448 |
| 67 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.05191643 |
| 68 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.04750550 |
| 69 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.03877212 |
| 70 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.02747871 |
| 71 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.02344591 |
| 72 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.02136958 |
| 73 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99266288 |
| 74 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98894241 |
| 75 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98894241 |
| 76 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.98835060 |
| 77 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.98583971 |
| 78 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.98281728 |
| 79 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.98173291 |
| 80 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.97249722 |
| 81 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96131929 |
| 82 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96059097 |
| 83 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.95780506 |
| 84 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.94704270 |
| 85 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.94448873 |
| 86 | ERA_21632823_ChIP-Seq_H3396_Human | 0.93311973 |
| 87 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.92147232 |
| 88 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.90411474 |
| 89 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.89770618 |
| 90 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.89325238 |
| 91 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.88913469 |
| 92 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.88494589 |
| 93 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.88357507 |
| 94 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.87044467 |
| 95 | P300_18555785_Chip-Seq_ESCs_Mouse | 0.86599345 |
| 96 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.86359580 |
| 97 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.86359580 |
| 98 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.86043007 |
| 99 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.85646513 |
| 100 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 0.85489608 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002102_abnormal_ear_morphology | 4.28401348 |
| 2 | MP0009379_abnormal_foot_pigmentation | 4.19157736 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.82291112 |
| 4 | MP0005646_abnormal_pituitary_gland | 2.68431014 |
| 5 | MP0005645_abnormal_hypothalamus_physiol | 2.58046137 |
| 6 | MP0003787_abnormal_imprinting | 2.54950880 |
| 7 | MP0004147_increased_porphyrin_level | 2.50001274 |
| 8 | MP0004885_abnormal_endolymph | 2.40172241 |
| 9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.30004354 |
| 10 | MP0008877_abnormal_DNA_methylation | 2.27235777 |
| 11 | MP0001188_hyperpigmentation | 2.25900660 |
| 12 | MP0001968_abnormal_touch/_nociception | 2.16714205 |
| 13 | MP0008872_abnormal_physiological_respon | 2.12986889 |
| 14 | MP0003011_delayed_dark_adaptation | 2.09055875 |
| 15 | MP0002736_abnormal_nociception_after | 1.90061442 |
| 16 | MP0004142_abnormal_muscle_tone | 1.82874841 |
| 17 | MP0005551_abnormal_eye_electrophysiolog | 1.81953629 |
| 18 | MP0003878_abnormal_ear_physiology | 1.77277051 |
| 19 | MP0005377_hearing/vestibular/ear_phenot | 1.77277051 |
| 20 | MP0008789_abnormal_olfactory_epithelium | 1.72010438 |
| 21 | MP0005084_abnormal_gallbladder_morpholo | 1.70931173 |
| 22 | MP0002272_abnormal_nervous_system | 1.69219596 |
| 23 | MP0006276_abnormal_autonomic_nervous | 1.68522867 |
| 24 | MP0002876_abnormal_thyroid_physiology | 1.67760325 |
| 25 | MP0003122_maternal_imprinting | 1.66949817 |
| 26 | MP0003646_muscle_fatigue | 1.66269170 |
| 27 | MP0002837_dystrophic_cardiac_calcinosis | 1.59547959 |
| 28 | MP0000372_irregular_coat_pigmentation | 1.57524743 |
| 29 | MP0008058_abnormal_DNA_repair | 1.56908042 |
| 30 | MP0004145_abnormal_muscle_electrophysio | 1.52897550 |
| 31 | MP0001986_abnormal_taste_sensitivity | 1.49771573 |
| 32 | MP0001984_abnormal_olfaction | 1.42477589 |
| 33 | MP0001529_abnormal_vocalization | 1.40321789 |
| 34 | MP0002733_abnormal_thermal_nociception | 1.37957164 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.36848284 |
| 36 | MP0002938_white_spotting | 1.34140901 |
| 37 | MP0002638_abnormal_pupillary_reflex | 1.30000550 |
| 38 | MP0002163_abnormal_gland_morphology | 1.29951008 |
| 39 | MP0003880_abnormal_central_pattern | 1.29658653 |
| 40 | MP0008775_abnormal_heart_ventricle | 1.29546851 |
| 41 | MP0002160_abnormal_reproductive_system | 1.28781239 |
| 42 | MP0001485_abnormal_pinna_reflex | 1.26659678 |
| 43 | MP0003121_genomic_imprinting | 1.22743031 |
| 44 | MP0002277_abnormal_respiratory_mucosa | 1.22305112 |
| 45 | MP0005394_taste/olfaction_phenotype | 1.21975329 |
| 46 | MP0005499_abnormal_olfactory_system | 1.21975329 |
| 47 | MP0005410_abnormal_fertilization | 1.21352404 |
| 48 | MP0002693_abnormal_pancreas_physiology | 1.20235478 |
| 49 | MP0002184_abnormal_innervation | 1.18927693 |
| 50 | MP0005389_reproductive_system_phenotype | 1.18918640 |
| 51 | MP0001293_anophthalmia | 1.18903401 |
| 52 | MP0000631_abnormal_neuroendocrine_gland | 1.18675984 |
| 53 | MP0001905_abnormal_dopamine_level | 1.16340636 |
| 54 | MP0001970_abnormal_pain_threshold | 1.15484580 |
| 55 | MP0003786_premature_aging | 1.11584417 |
| 56 | MP0003879_abnormal_hair_cell | 1.11318442 |
| 57 | MP0002095_abnormal_skin_pigmentation | 1.10833597 |
| 58 | MP0009333_abnormal_splenocyte_physiolog | 1.07060188 |
| 59 | MP0009745_abnormal_behavioral_response | 1.04426457 |
| 60 | MP0003186_abnormal_redox_activity | 1.03770265 |
| 61 | MP0001919_abnormal_reproductive_system | 1.03523228 |
| 62 | MP0002653_abnormal_ependyma_morphology | 1.03401406 |
| 63 | MP0002557_abnormal_social/conspecific_i | 1.01641240 |
| 64 | MP0009046_muscle_twitch | 0.97793255 |
| 65 | MP0002735_abnormal_chemical_nociception | 0.97744789 |
| 66 | MP0002138_abnormal_hepatobiliary_system | 0.96904960 |
| 67 | MP0000647_abnormal_sebaceous_gland | 0.96625459 |
| 68 | MP0005636_abnormal_mineral_homeostasis | 0.96315782 |
| 69 | MP0003718_maternal_effect | 0.96197894 |
| 70 | MP0009785_altered_susceptibility_to | 0.92228709 |
| 71 | MP0000955_abnormal_spinal_cord | 0.90968676 |
| 72 | MP0005195_abnormal_posterior_eye | 0.89381213 |
| 73 | MP0000778_abnormal_nervous_system | 0.87740418 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.86977421 |
| 75 | MP0004742_abnormal_vestibular_system | 0.85930560 |
| 76 | MP0005379_endocrine/exocrine_gland_phen | 0.85393578 |
| 77 | MP0002572_abnormal_emotion/affect_behav | 0.84947618 |
| 78 | MP0005187_abnormal_penis_morphology | 0.84743850 |
| 79 | MP0000026_abnormal_inner_ear | 0.83677499 |
| 80 | MP0002752_abnormal_somatic_nervous | 0.83519521 |
| 81 | MP0000015_abnormal_ear_pigmentation | 0.82405129 |
| 82 | MP0001486_abnormal_startle_reflex | 0.81618375 |
| 83 | MP0001835_abnormal_antigen_presentation | 0.80590341 |
| 84 | MP0008057_abnormal_DNA_replication | 0.80044991 |
| 85 | MP0005671_abnormal_response_to | 0.79912909 |
| 86 | MP0002734_abnormal_mechanical_nocicepti | 0.79020383 |
| 87 | MP0005075_abnormal_melanosome_morpholog | 0.78400856 |
| 88 | MP0005253_abnormal_eye_physiology | 0.78279731 |
| 89 | MP0001963_abnormal_hearing_physiology | 0.77086429 |
| 90 | MP0010386_abnormal_urinary_bladder | 0.76507267 |
| 91 | MP0002822_catalepsy | 0.74298687 |
| 92 | MP0003283_abnormal_digestive_organ | 0.73579833 |
| 93 | MP0000230_abnormal_systemic_arterial | 0.73382874 |
| 94 | MP0002234_abnormal_pharynx_morphology | 0.72647876 |
| 95 | MP0002210_abnormal_sex_determination | 0.72465865 |
| 96 | MP0002067_abnormal_sensory_capabilities | 0.72313193 |
| 97 | MP0001440_abnormal_grooming_behavior | 0.72085993 |
| 98 | MP0005423_abnormal_somatic_nervous | 0.70258308 |
| 99 | MP0004133_heterotaxia | 0.69495766 |
| 100 | MP0003635_abnormal_synaptic_transmissio | 0.69410606 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.14018913 |
| 2 | Methylmalonic acidemia (HP:0002912) | 4.00662136 |
| 3 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 4.00152738 |
| 4 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.74405914 |
| 5 | Acute encephalopathy (HP:0006846) | 3.66331007 |
| 6 | Pancreatic cysts (HP:0001737) | 3.55565185 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.54474199 |
| 8 | Mitochondrial inheritance (HP:0001427) | 3.44348354 |
| 9 | Increased CSF lactate (HP:0002490) | 3.38618370 |
| 10 | Progressive macrocephaly (HP:0004481) | 3.37326781 |
| 11 | True hermaphroditism (HP:0010459) | 3.37062979 |
| 12 | Decreased central vision (HP:0007663) | 3.35907614 |
| 13 | Nephronophthisis (HP:0000090) | 3.31056221 |
| 14 | Pancreatic fibrosis (HP:0100732) | 3.21273462 |
| 15 | Abnormality of midbrain morphology (HP:0002418) | 3.19857235 |
| 16 | Molar tooth sign on MRI (HP:0002419) | 3.19857235 |
| 17 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.12619814 |
| 18 | Reticulocytopenia (HP:0001896) | 3.03194082 |
| 19 | Retrobulbar optic neuritis (HP:0100654) | 3.01604971 |
| 20 | Optic neuritis (HP:0100653) | 3.01604971 |
| 21 | Attenuation of retinal blood vessels (HP:0007843) | 2.95928492 |
| 22 | Increased hepatocellular lipid droplets (HP:0006565) | 2.95137466 |
| 23 | 3-Methylglutaconic aciduria (HP:0003535) | 2.93220873 |
| 24 | Hepatocellular necrosis (HP:0001404) | 2.92799597 |
| 25 | Congenital stationary night blindness (HP:0007642) | 2.91693758 |
| 26 | Methylmalonic aciduria (HP:0012120) | 2.91290604 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90686318 |
| 28 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.87923808 |
| 29 | Pendular nystagmus (HP:0012043) | 2.82627187 |
| 30 | Abnormal number of erythroid precursors (HP:0012131) | 2.79440954 |
| 31 | Cerebral edema (HP:0002181) | 2.78979678 |
| 32 | Optic disc pallor (HP:0000543) | 2.69444986 |
| 33 | Colon cancer (HP:0003003) | 2.66194347 |
| 34 | Macrocytic anemia (HP:0001972) | 2.65224513 |
| 35 | Abnormality of the renal medulla (HP:0100957) | 2.61645332 |
| 36 | Hepatic necrosis (HP:0002605) | 2.59323268 |
| 37 | Increased serum lactate (HP:0002151) | 2.56674108 |
| 38 | Reduced antithrombin III activity (HP:0001976) | 2.56312066 |
| 39 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.47138597 |
| 40 | Abnormality of the renal cortex (HP:0011035) | 2.45924581 |
| 41 | Hyperglycinemia (HP:0002154) | 2.44541320 |
| 42 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.43888418 |
| 43 | Type I transferrin isoform profile (HP:0003642) | 2.41979040 |
| 44 | Absent thumb (HP:0009777) | 2.37149732 |
| 45 | Abnormality of vitamin B metabolism (HP:0004340) | 2.35533905 |
| 46 | Constricted visual fields (HP:0001133) | 2.32971691 |
| 47 | Orchitis (HP:0100796) | 2.31766405 |
| 48 | Keratoconus (HP:0000563) | 2.29461604 |
| 49 | Increased corneal curvature (HP:0100692) | 2.29461604 |
| 50 | Septo-optic dysplasia (HP:0100842) | 2.25537469 |
| 51 | Congenital hepatic fibrosis (HP:0002612) | 2.25226507 |
| 52 | Abolished electroretinogram (ERG) (HP:0000550) | 2.24341091 |
| 53 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.23874540 |
| 54 | Hypoproteinemia (HP:0003075) | 2.22940651 |
| 55 | Medial flaring of the eyebrow (HP:0010747) | 2.20317219 |
| 56 | Type II lissencephaly (HP:0007260) | 2.19369841 |
| 57 | Hypoplasia of the pons (HP:0012110) | 2.19204306 |
| 58 | Stomatitis (HP:0010280) | 2.19188904 |
| 59 | Lactic acidosis (HP:0003128) | 2.19066515 |
| 60 | Renal cortical cysts (HP:0000803) | 2.12387587 |
| 61 | Abnormality of the pons (HP:0007361) | 2.10406836 |
| 62 | Tubulointerstitial fibrosis (HP:0005576) | 2.09017078 |
| 63 | Bony spicule pigmentary retinopathy (HP:0007737) | 2.08749437 |
| 64 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.07773749 |
| 65 | Exercise intolerance (HP:0003546) | 2.06909325 |
| 66 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.02289877 |
| 67 | Lethargy (HP:0001254) | 2.01421755 |
| 68 | Ketosis (HP:0001946) | 1.93941762 |
| 69 | Anencephaly (HP:0002323) | 1.93390809 |
| 70 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.92839972 |
| 71 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.92839972 |
| 72 | Adactyly (HP:0009776) | 1.92572566 |
| 73 | Large for gestational age (HP:0001520) | 1.92471097 |
| 74 | Abnormality of the labia minora (HP:0012880) | 1.91612560 |
| 75 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.91252863 |
| 76 | Dicarboxylic aciduria (HP:0003215) | 1.91252863 |
| 77 | Asplenia (HP:0001746) | 1.90870663 |
| 78 | Renal Fanconi syndrome (HP:0001994) | 1.90788422 |
| 79 | Cystic liver disease (HP:0006706) | 1.89610099 |
| 80 | Keratoconjunctivitis sicca (HP:0001097) | 1.89117555 |
| 81 | Abnormal protein glycosylation (HP:0012346) | 1.89010625 |
| 82 | Abnormal glycosylation (HP:0012345) | 1.89010625 |
| 83 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.89010625 |
| 84 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.89010625 |
| 85 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.87956503 |
| 86 | Respiratory failure (HP:0002878) | 1.87016224 |
| 87 | Leukodystrophy (HP:0002415) | 1.86229605 |
| 88 | Sclerocornea (HP:0000647) | 1.85824136 |
| 89 | Exertional dyspnea (HP:0002875) | 1.84800679 |
| 90 | Agitation (HP:0000713) | 1.83452356 |
| 91 | Abnormality of DNA repair (HP:0003254) | 1.82849531 |
| 92 | Abnormality of homocysteine metabolism (HP:0010919) | 1.82528572 |
| 93 | Homocystinuria (HP:0002156) | 1.82528572 |
| 94 | Increased intramyocellular lipid droplets (HP:0012240) | 1.82011171 |
| 95 | Abnormality of serum amino acid levels (HP:0003112) | 1.81320636 |
| 96 | Keratoconjunctivitis (HP:0001096) | 1.80874330 |
| 97 | Hypochromic microcytic anemia (HP:0004840) | 1.80101016 |
| 98 | Male pseudohermaphroditism (HP:0000037) | 1.79663195 |
| 99 | Optic nerve hypoplasia (HP:0000609) | 1.78774530 |
| 100 | Inability to walk (HP:0002540) | 1.77584514 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP2K6 | 3.82122802 |
| 2 | ZAK | 3.19715754 |
| 3 | ADRBK2 | 2.73978798 |
| 4 | BCKDK | 2.73127761 |
| 5 | NUAK1 | 2.66584145 |
| 6 | TSSK6 | 2.62997401 |
| 7 | TLK1 | 2.59436436 |
| 8 | VRK2 | 2.49162640 |
| 9 | PINK1 | 2.40796006 |
| 10 | GRK1 | 2.39084812 |
| 11 | TIE1 | 2.30508600 |
| 12 | TXK | 2.29233033 |
| 13 | WNK4 | 2.25245108 |
| 14 | STK16 | 2.16992814 |
| 15 | TAF1 | 1.93595020 |
| 16 | DYRK2 | 1.89719528 |
| 17 | MST4 | 1.86911290 |
| 18 | PASK | 1.86005597 |
| 19 | FRK | 1.72745178 |
| 20 | STK39 | 1.62408584 |
| 21 | BMPR1B | 1.55645115 |
| 22 | WNK3 | 1.45938188 |
| 23 | CAMKK2 | 1.37642678 |
| 24 | NME1 | 1.26415442 |
| 25 | PBK | 1.25291580 |
| 26 | NLK | 1.24703699 |
| 27 | VRK1 | 1.23982632 |
| 28 | TAOK3 | 1.16150313 |
| 29 | OXSR1 | 1.16014088 |
| 30 | MKNK2 | 1.13947199 |
| 31 | NEK1 | 1.12180005 |
| 32 | PLK3 | 1.11839285 |
| 33 | MAPK13 | 1.10295841 |
| 34 | PHKG1 | 1.09426474 |
| 35 | PHKG2 | 1.09426474 |
| 36 | ITK | 1.02327206 |
| 37 | CDK19 | 1.00791956 |
| 38 | TRIM28 | 0.99473373 |
| 39 | TEC | 0.98957397 |
| 40 | CSNK1G3 | 0.98797291 |
| 41 | WNK1 | 0.96847052 |
| 42 | EIF2AK3 | 0.96247348 |
| 43 | DAPK2 | 0.93610655 |
| 44 | CSNK1G1 | 0.93438653 |
| 45 | PRKCG | 0.91529855 |
| 46 | MARK1 | 0.91209028 |
| 47 | CDC7 | 0.91006437 |
| 48 | CSNK1G2 | 0.89025904 |
| 49 | CAMKK1 | 0.87703959 |
| 50 | NTRK2 | 0.86953881 |
| 51 | CSNK1A1L | 0.85954782 |
| 52 | CASK | 0.84618169 |
| 53 | MKNK1 | 0.84566604 |
| 54 | ATR | 0.81364096 |
| 55 | PLK2 | 0.77280144 |
| 56 | ADRBK1 | 0.77084790 |
| 57 | INSRR | 0.75184767 |
| 58 | MAP2K7 | 0.74220540 |
| 59 | TGFBR1 | 0.72982633 |
| 60 | RPS6KA5 | 0.72697221 |
| 61 | PLK4 | 0.70384568 |
| 62 | IKBKE | 0.66112260 |
| 63 | IKBKB | 0.65621063 |
| 64 | GRK5 | 0.63351011 |
| 65 | PRKCH | 0.61783203 |
| 66 | PRKCQ | 0.59504518 |
| 67 | MINK1 | 0.59493160 |
| 68 | CSNK1A1 | 0.59233264 |
| 69 | CSNK1E | 0.58939222 |
| 70 | CSNK2A2 | 0.57163963 |
| 71 | PRKCE | 0.56626028 |
| 72 | PNCK | 0.53159967 |
| 73 | EPHA4 | 0.51458644 |
| 74 | CAMK2D | 0.51332766 |
| 75 | MAP4K1 | 0.50257168 |
| 76 | BCR | 0.48218266 |
| 77 | TNIK | 0.48158545 |
| 78 | CAMK2A | 0.47636417 |
| 79 | PRKACA | 0.47281851 |
| 80 | KIT | 0.47116621 |
| 81 | DYRK1B | 0.47006829 |
| 82 | CSNK2A1 | 0.44656608 |
| 83 | EIF2AK1 | 0.43796406 |
| 84 | NME2 | 0.43459743 |
| 85 | PLK1 | 0.41113941 |
| 86 | ALK | 0.40905638 |
| 87 | DAPK3 | 0.40620606 |
| 88 | STK11 | 0.40456652 |
| 89 | MAP3K4 | 0.37994577 |
| 90 | PIK3CA | 0.37707906 |
| 91 | JAK3 | 0.37589134 |
| 92 | PAK3 | 0.36637057 |
| 93 | PRKCA | 0.35203201 |
| 94 | RPS6KA6 | 0.34710619 |
| 95 | ATM | 0.33786393 |
| 96 | CAMK1D | 0.33353522 |
| 97 | ABL2 | 0.31421912 |
| 98 | OBSCN | 0.29946925 |
| 99 | MAP4K2 | 0.29364596 |
| 100 | EIF2AK2 | 0.28403474 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 3.54562417 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 3.48909403 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.15820133 |
| 4 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.98226276 |
| 5 | Protein export_Homo sapiens_hsa03060 | 2.92482149 |
| 6 | RNA polymerase_Homo sapiens_hsa03020 | 2.92432106 |
| 7 | Parkinsons disease_Homo sapiens_hsa05012 | 2.76981612 |
| 8 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.76032527 |
| 9 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.30439555 |
| 10 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.16503280 |
| 11 | Phototransduction_Homo sapiens_hsa04744 | 2.03456073 |
| 12 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.00118596 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.99577820 |
| 14 | Huntingtons disease_Homo sapiens_hsa05016 | 1.88079515 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 1.82996511 |
| 16 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.76078642 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 1.74885254 |
| 18 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.71759513 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.65071163 |
| 20 | Homologous recombination_Homo sapiens_hsa03440 | 1.61639619 |
| 21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.60483563 |
| 22 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.60089647 |
| 23 | Allograft rejection_Homo sapiens_hsa05330 | 1.55825425 |
| 24 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.54413129 |
| 25 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.51816750 |
| 26 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.49572359 |
| 27 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.47126592 |
| 28 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.44158899 |
| 29 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.43450602 |
| 30 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.38073192 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.32873888 |
| 32 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.32513005 |
| 33 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.30460284 |
| 34 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.27655553 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.25409612 |
| 36 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.22096850 |
| 37 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.19744358 |
| 38 | Purine metabolism_Homo sapiens_hsa00230 | 1.16998350 |
| 39 | Mismatch repair_Homo sapiens_hsa03430 | 1.16761348 |
| 40 | RNA transport_Homo sapiens_hsa03013 | 1.13662360 |
| 41 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.09924367 |
| 42 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.08372297 |
| 43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.07806675 |
| 44 | Base excision repair_Homo sapiens_hsa03410 | 1.04059997 |
| 45 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.03302617 |
| 46 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.99201544 |
| 47 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.97114035 |
| 48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95891333 |
| 49 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.94469052 |
| 50 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.90481256 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.88875282 |
| 52 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.85225062 |
| 53 | Olfactory transduction_Homo sapiens_hsa04740 | 0.81559251 |
| 54 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.81029172 |
| 55 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.80611337 |
| 56 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.80545559 |
| 57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.79890639 |
| 58 | Metabolic pathways_Homo sapiens_hsa01100 | 0.77521424 |
| 59 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.73901145 |
| 60 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.72706560 |
| 61 | Nicotine addiction_Homo sapiens_hsa05033 | 0.69701205 |
| 62 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.68464642 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.66270767 |
| 64 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65287589 |
| 65 | Spliceosome_Homo sapiens_hsa03040 | 0.63927573 |
| 66 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.63793287 |
| 67 | DNA replication_Homo sapiens_hsa03030 | 0.61896727 |
| 68 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.60666867 |
| 69 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.59696752 |
| 70 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.59153285 |
| 71 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.58729263 |
| 72 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.54299837 |
| 73 | Insulin secretion_Homo sapiens_hsa04911 | 0.52701730 |
| 74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.51667369 |
| 75 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.51329464 |
| 76 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.50749222 |
| 77 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.50149596 |
| 78 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.49166332 |
| 79 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48919070 |
| 80 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.48691295 |
| 81 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.44981662 |
| 82 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44651247 |
| 83 | Morphine addiction_Homo sapiens_hsa05032 | 0.43634746 |
| 84 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.43151906 |
| 85 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.42756702 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.41784041 |
| 87 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.41505068 |
| 88 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.37991657 |
| 89 | Sulfur relay system_Homo sapiens_hsa04122 | 0.37728860 |
| 90 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.37121531 |
| 91 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.36918704 |
| 92 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.35408755 |
| 93 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.34000140 |
| 94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.33977569 |
| 95 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.33453333 |
| 96 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.33240298 |
| 97 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.32451152 |
| 98 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.32046630 |
| 99 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.30340795 |
| 100 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.29553277 |

