RPL5P24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)5.96576777
2maturation of SSU-rRNA (GO:0030490)5.33671053
3viral transcription (GO:0019083)5.21663539
4ATP synthesis coupled proton transport (GO:0015986)5.18475660
5energy coupled proton transport, down electrochemical gradient (GO:0015985)5.18475660
6translational termination (GO:0006415)5.06647983
7mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.70089823
8SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.63588867
9cotranslational protein targeting to membrane (GO:0006613)4.61092793
10protein targeting to ER (GO:0045047)4.55676863
11water-soluble vitamin biosynthetic process (GO:0042364)4.55345153
12mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.44368323
13translational elongation (GO:0006414)4.42048776
14establishment of protein localization to endoplasmic reticulum (GO:0072599)4.36122412
15protein neddylation (GO:0045116)4.34211817
16mitochondrial respiratory chain complex I assembly (GO:0032981)4.34083851
17NADH dehydrogenase complex assembly (GO:0010257)4.34083851
18mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.34083851
19protein localization to endoplasmic reticulum (GO:0070972)4.30581340
20protein complex biogenesis (GO:0070271)4.24360650
21ribosomal small subunit biogenesis (GO:0042274)4.20182082
22mitochondrial respiratory chain complex assembly (GO:0033108)3.94220355
23behavioral response to nicotine (GO:0035095)3.93953013
24ribosomal large subunit biogenesis (GO:0042273)3.93111081
25regulation of cilium movement (GO:0003352)3.86736273
26viral life cycle (GO:0019058)3.82810729
27DNA deamination (GO:0045006)3.80879191
28cellular protein complex disassembly (GO:0043624)3.80069894
29tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.79216358
30RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.79216358
31electron transport chain (GO:0022900)3.77384354
32respiratory electron transport chain (GO:0022904)3.75296109
33establishment of protein localization to mitochondrial membrane (GO:0090151)3.70824218
34translational initiation (GO:0006413)3.69427576
35nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.51264464
36translation (GO:0006412)3.48860129
37protein-cofactor linkage (GO:0018065)3.45907422
38respiratory chain complex IV assembly (GO:0008535)3.38685565
39epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.36279897
40neuron fate determination (GO:0048664)3.33927596
41nonmotile primary cilium assembly (GO:0035058)3.32709672
42nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.30337407
43chaperone-mediated protein transport (GO:0072321)3.23841169
44exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.19389273
45protein complex disassembly (GO:0043241)3.18960062
46mannosylation (GO:0097502)3.14501176
47ATP biosynthetic process (GO:0006754)3.13547449
48cellular component biogenesis (GO:0044085)3.13198072
49purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.10945016
50retinal rod cell development (GO:0046548)3.07765076
51purine nucleoside triphosphate biosynthetic process (GO:0009145)3.07292541
52piRNA metabolic process (GO:0034587)3.07177243
53macromolecular complex disassembly (GO:0032984)3.05509264
54preassembly of GPI anchor in ER membrane (GO:0016254)3.04686275
55hydrogen ion transmembrane transport (GO:1902600)3.03505315
56GTP biosynthetic process (GO:0006183)3.02703978
57ubiquinone biosynthetic process (GO:0006744)3.00869573
58somite development (GO:0061053)3.00792540
59aldehyde catabolic process (GO:0046185)2.99510346
60axoneme assembly (GO:0035082)2.92974373
61base-excision repair, AP site formation (GO:0006285)2.91966368
62protein polyglutamylation (GO:0018095)2.91906407
63ribonucleoprotein complex biogenesis (GO:0022613)2.87697384
64proton transport (GO:0015992)2.86754652
65protein targeting to membrane (GO:0006612)2.85400352
66termination of RNA polymerase III transcription (GO:0006386)2.82695504
67transcription elongation from RNA polymerase III promoter (GO:0006385)2.82695504
68nuclear-transcribed mRNA catabolic process (GO:0000956)2.82005159
69hydrogen transport (GO:0006818)2.81426589
70platelet dense granule organization (GO:0060155)2.79918094
71ubiquinone metabolic process (GO:0006743)2.79712836
72cytochrome complex assembly (GO:0017004)2.77146945
73detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.74055715
74epithelial cilium movement (GO:0003351)2.71019512
75proteasome assembly (GO:0043248)2.70786031
76response to pheromone (GO:0019236)2.70348997
77regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.70003069
78ribonucleoside triphosphate biosynthetic process (GO:0009201)2.69358499
79GPI anchor metabolic process (GO:0006505)2.68918915
80tRNA processing (GO:0008033)2.67796274
81resolution of meiotic recombination intermediates (GO:0000712)2.67475379
82mRNA catabolic process (GO:0006402)2.65075580
83replication fork processing (GO:0031297)2.62255120
84regulation of microtubule-based movement (GO:0060632)2.61227504
85negative regulation of appetite (GO:0032099)2.58884898
86negative regulation of response to food (GO:0032096)2.58884898
87spliceosomal complex assembly (GO:0000245)2.58494696
88GPI anchor biosynthetic process (GO:0006506)2.56514474
89rRNA metabolic process (GO:0016072)2.54696161
90pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.54372675
91negative regulation of telomere maintenance (GO:0032205)2.53936874
92rRNA processing (GO:0006364)2.53236567
93peptidyl-histidine modification (GO:0018202)2.49857639
94photoreceptor cell development (GO:0042461)2.49830067
95cell proliferation in forebrain (GO:0021846)2.49519944
96deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.49257337
97substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.48939609
98substrate-independent telencephalic tangential migration (GO:0021826)2.48939609
99cullin deneddylation (GO:0010388)2.48599540
100UTP biosynthetic process (GO:0006228)2.45947436

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GABP_17652178_ChIP-ChIP_JURKAT_Human4.01410097
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.89718891
3VDR_22108803_ChIP-Seq_LS180_Human3.50019593
4E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.37358610
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.33978383
6HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human3.21927368
7SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.92686506
8ZNF274_21170338_ChIP-Seq_K562_Hela2.92014759
9EZH2_22144423_ChIP-Seq_EOC_Human2.87818399
10FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.63472458
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.54986812
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.54626872
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.49663510
14ELF1_17652178_ChIP-ChIP_JURKAT_Human2.49154695
15MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.26281479
16VDR_23849224_ChIP-Seq_CD4+_Human2.21094276
17TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.18035584
18IGF1R_20145208_ChIP-Seq_DFB_Human1.92680203
19FOXP3_21729870_ChIP-Seq_TREG_Human1.87940641
20FLI1_27457419_Chip-Seq_LIVER_Mouse1.83441920
21MYC_18940864_ChIP-ChIP_HL60_Human1.83045575
22EWS_26573619_Chip-Seq_HEK293_Human1.81444967
23CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.78657555
24ELK1_19687146_ChIP-ChIP_HELA_Human1.78094020
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.75797644
26CREB1_15753290_ChIP-ChIP_HEK293T_Human1.74948759
27MYC_18555785_ChIP-Seq_MESCs_Mouse1.73659705
28TP53_22573176_ChIP-Seq_HFKS_Human1.73526166
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.58704317
30NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.54741678
31NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.54407705
32FUS_26573619_Chip-Seq_HEK293_Human1.49802913
33PCGF2_27294783_Chip-Seq_ESCs_Mouse1.48300798
34CTBP1_25329375_ChIP-Seq_LNCAP_Human1.48176633
35MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.44091290
36EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.39967064
37TTF2_22483619_ChIP-Seq_HELA_Human1.39909572
38BMI1_23680149_ChIP-Seq_NPCS_Mouse1.39298098
39NCOR_22424771_ChIP-Seq_293T_Human1.33742849
40CBX2_27304074_Chip-Seq_ESCs_Mouse1.30969539
41AUTS2_25519132_ChIP-Seq_293T-REX_Human1.29831695
42NANOG_20526341_ChIP-Seq_ESCs_Human1.29054215
43P300_19829295_ChIP-Seq_ESCs_Human1.28531121
44IRF1_19129219_ChIP-ChIP_H3396_Human1.28250822
45GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.27757254
46ETV2_25802403_ChIP-Seq_MESCs_Mouse1.26312328
47ZFP57_27257070_Chip-Seq_ESCs_Mouse1.24314926
48PCGF2_27294783_Chip-Seq_NPCs_Mouse1.24156741
49POU5F1_16153702_ChIP-ChIP_HESCs_Human1.23499361
50GATA3_21878914_ChIP-Seq_MCF-7_Human1.23342469
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.22825580
52MYC_18358816_ChIP-ChIP_MESCs_Mouse1.21862203
53CTBP2_25329375_ChIP-Seq_LNCAP_Human1.20135861
54YY1_21170310_ChIP-Seq_MESCs_Mouse1.18498935
55E2F4_17652178_ChIP-ChIP_JURKAT_Human1.17033724
56TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.15396619
57NANOG_19829295_ChIP-Seq_ESCs_Human1.15038312
58SOX2_19829295_ChIP-Seq_ESCs_Human1.15038312
59CBP_20019798_ChIP-Seq_JUKART_Human1.14145494
60IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14145494
61AR_20517297_ChIP-Seq_VCAP_Human1.13612242
62TAF15_26573619_Chip-Seq_HEK293_Human1.13344076
63GABP_19822575_ChIP-Seq_HepG2_Human1.12681721
64FOXA1_27270436_Chip-Seq_PROSTATE_Human1.12490282
65FOXA1_25329375_ChIP-Seq_VCAP_Human1.12490282
66GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.10822528
67XRN2_22483619_ChIP-Seq_HELA_Human1.10045130
68FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.04254754
69CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.03961125
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.03587569
71ER_23166858_ChIP-Seq_MCF-7_Human1.03065921
72ERA_21632823_ChIP-Seq_H3396_Human1.03055649
73TAF2_19829295_ChIP-Seq_ESCs_Human1.02819609
74TP63_19390658_ChIP-ChIP_HaCaT_Human0.99496480
75SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.98218663
76REST_21632747_ChIP-Seq_MESCs_Mouse0.97715979
77MYC_19829295_ChIP-Seq_ESCs_Human0.97514318
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96140753
79TCF4_22108803_ChIP-Seq_LS180_Human0.94998363
80RNF2_27304074_Chip-Seq_NSC_Mouse0.94330688
81KLF5_20875108_ChIP-Seq_MESCs_Mouse0.94163674
82RBPJ_21746931_ChIP-Seq_IB4_Human0.93133684
83HOXB7_26014856_ChIP-Seq_BT474_Human0.92674013
84MYC_19030024_ChIP-ChIP_MESCs_Mouse0.91552022
85EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.91531671
86BCAT_22108803_ChIP-Seq_LS180_Human0.91470748
87RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.90854245
88SUZ12_27294783_Chip-Seq_NPCs_Mouse0.90826498
89MYC_19079543_ChIP-ChIP_MESCs_Mouse0.90617303
90CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.90534570
91POU3F2_20337985_ChIP-ChIP_501MEL_Human0.88510770
92NFE2_27457419_Chip-Seq_LIVER_Mouse0.88508857
93NOTCH1_21737748_ChIP-Seq_TLL_Human0.85290961
94GATA6_21074721_ChIP-Seq_CACO-2_Human0.84721372
95FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.83955731
96TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.82818314
97POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.82818314
98FOXH1_21741376_ChIP-Seq_EPCs_Human0.82267061
99PADI4_21655091_ChIP-ChIP_MCF-7_Human0.82123288
100ETV1_20927104_ChIP-Seq_GIST48_Human0.81771395

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0006292_abnormal_olfactory_placode3.73147607
2MP0009379_abnormal_foot_pigmentation3.55168512
3MP0008877_abnormal_DNA_methylation2.93946075
4MP0003787_abnormal_imprinting2.70806440
5MP0008789_abnormal_olfactory_epithelium2.47727074
6MP0004147_increased_porphyrin_level2.43024902
7MP0002102_abnormal_ear_morphology2.38833442
8MP0001984_abnormal_olfaction2.30556286
9MP0003122_maternal_imprinting2.28097239
10MP0004142_abnormal_muscle_tone2.25680117
11MP0005646_abnormal_pituitary_gland2.22212611
12MP0005551_abnormal_eye_electrophysiolog2.21363480
13MP0001968_abnormal_touch/_nociception2.12851256
14MP0002163_abnormal_gland_morphology2.01471801
15MP0008872_abnormal_physiological_respon1.98125833
16MP0006072_abnormal_retinal_apoptosis1.95581557
17MP0004885_abnormal_endolymph1.90465268
18MP0002736_abnormal_nociception_after1.81539888
19MP0003195_calcinosis1.80835429
20MP0005394_taste/olfaction_phenotype1.80428857
21MP0005499_abnormal_olfactory_system1.80428857
22MP0002837_dystrophic_cardiac_calcinosis1.79384400
23MP0008875_abnormal_xenobiotic_pharmacok1.78480157
24MP0002653_abnormal_ependyma_morphology1.75236644
25MP0000372_irregular_coat_pigmentation1.74751358
26MP0003121_genomic_imprinting1.68441170
27MP0003693_abnormal_embryo_hatching1.68339662
28MP0001986_abnormal_taste_sensitivity1.67035146
29MP0005645_abnormal_hypothalamus_physiol1.61395496
30MP0005379_endocrine/exocrine_gland_phen1.56907591
31MP0002277_abnormal_respiratory_mucosa1.56065968
32MP0006276_abnormal_autonomic_nervous1.54443529
33MP0004145_abnormal_muscle_electrophysio1.54183436
34MP0000631_abnormal_neuroendocrine_gland1.52415237
35MP0003880_abnormal_central_pattern1.48481854
36MP0001485_abnormal_pinna_reflex1.42340746
37MP0003646_muscle_fatigue1.42302269
38MP0002938_white_spotting1.41679558
39MP0005671_abnormal_response_to1.38355211
40MP0002876_abnormal_thyroid_physiology1.38185995
41MP0005389_reproductive_system_phenotype1.37204536
42MP0001919_abnormal_reproductive_system1.36517931
43MP0005084_abnormal_gallbladder_morpholo1.34776012
44MP0003186_abnormal_redox_activity1.33719962
45MP0001873_stomach_inflammation1.32999411
46MP0005253_abnormal_eye_physiology1.25966220
47MP0003011_delayed_dark_adaptation1.25426428
48MP0005377_hearing/vestibular/ear_phenot1.24472997
49MP0003878_abnormal_ear_physiology1.24472997
50MP0005075_abnormal_melanosome_morpholog1.23632678
51MP0003567_abnormal_fetal_cardiomyocyte1.17236400
52MP0002557_abnormal_social/conspecific_i1.16350994
53MP0002160_abnormal_reproductive_system1.14974049
54MP0001293_anophthalmia1.12195478
55MP0003136_yellow_coat_color1.12072899
56MP0002272_abnormal_nervous_system1.10613870
57MP0003718_maternal_effect1.09960685
58MP0003123_paternal_imprinting1.09222866
59MP0000049_abnormal_middle_ear1.07042115
60MP0003786_premature_aging1.06918895
61MP0009046_muscle_twitch1.05330028
62MP0009745_abnormal_behavioral_response1.04829054
63MP0005195_abnormal_posterior_eye1.04665468
64MP0004133_heterotaxia1.04564827
65MP0008058_abnormal_DNA_repair1.04183795
66MP0002234_abnormal_pharynx_morphology0.97779546
67MP0008995_early_reproductive_senescence0.97642940
68MP0008775_abnormal_heart_ventricle0.95446053
69MP0001905_abnormal_dopamine_level0.94182535
70MP0001502_abnormal_circadian_rhythm0.93890137
71MP0001529_abnormal_vocalization0.93723394
72MP0001970_abnormal_pain_threshold0.93084669
73MP0002095_abnormal_skin_pigmentation0.90537359
74MP0002572_abnormal_emotion/affect_behav0.89046285
75MP0005410_abnormal_fertilization0.88724948
76MP0005636_abnormal_mineral_homeostasis0.88294510
77MP0002752_abnormal_somatic_nervous0.87215356
78MP0000427_abnormal_hair_cycle0.86337101
79MP0001440_abnormal_grooming_behavior0.86042029
80MP0002184_abnormal_innervation0.84311956
81MP0004742_abnormal_vestibular_system0.84083574
82MP0003806_abnormal_nucleotide_metabolis0.79943181
83MP0000778_abnormal_nervous_system0.79668432
84MP0000026_abnormal_inner_ear0.79479886
85MP0002733_abnormal_thermal_nociception0.79294806
86MP0001663_abnormal_digestive_system0.78497549
87MP0002210_abnormal_sex_determination0.77853287
88MP0001324_abnormal_eye_pigmentation0.77748216
89MP0004924_abnormal_behavior0.77375832
90MP0005386_behavior/neurological_phenoty0.77375832
91MP0006036_abnormal_mitochondrial_physio0.74498106
92MP0000955_abnormal_spinal_cord0.73506438
93MP0002751_abnormal_autonomic_nervous0.73459908
94MP0001501_abnormal_sleep_pattern0.72098288
95MP0001486_abnormal_startle_reflex0.72076781
96MP0001963_abnormal_hearing_physiology0.71668104
97MP0003119_abnormal_digestive_system0.71479549
98MP0003698_abnormal_male_reproductive0.70545637
99MP0002138_abnormal_hepatobiliary_system0.69346575
100MP0000653_abnormal_sex_gland0.69072835

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.75533316
2Abnormal mitochondria in muscle tissue (HP:0008316)4.19273719
3Acute encephalopathy (HP:0006846)4.16800087
4Mitochondrial inheritance (HP:0001427)4.11911984
5Progressive macrocephaly (HP:0004481)3.92913962
6Increased CSF lactate (HP:0002490)3.80760748
7Absent rod-and cone-mediated responses on ERG (HP:0007688)3.60959744
8Reticulocytopenia (HP:0001896)3.51040181
9Pancreatic fibrosis (HP:0100732)3.44675262
10Pancreatic cysts (HP:0001737)3.34865105
11Hepatocellular necrosis (HP:0001404)3.29972094
12Lipid accumulation in hepatocytes (HP:0006561)3.27228570
13Abnormality of cells of the erythroid lineage (HP:0012130)3.26066457
14Increased hepatocellular lipid droplets (HP:0006565)3.23906971
15Molar tooth sign on MRI (HP:0002419)3.09944245
16Abnormality of midbrain morphology (HP:0002418)3.09944245
17Hepatic necrosis (HP:0002605)3.07763929
183-Methylglutaconic aciduria (HP:0003535)3.04691054
19Congenital stationary night blindness (HP:0007642)3.04217049
20Optic disc pallor (HP:0000543)3.03089631
21Abnormal rod and cone electroretinograms (HP:0008323)3.01495013
22Type II lissencephaly (HP:0007260)3.00461626
23Cerebral edema (HP:0002181)2.96065205
24True hermaphroditism (HP:0010459)2.94111499
25Absent/shortened dynein arms (HP:0200106)2.93751722
26Dynein arm defect of respiratory motile cilia (HP:0012255)2.93751722
27Abnormal number of erythroid precursors (HP:0012131)2.81117967
28Renal Fanconi syndrome (HP:0001994)2.76379309
29Nephronophthisis (HP:0000090)2.72924350
30Pendular nystagmus (HP:0012043)2.67073026
31Macrocytic anemia (HP:0001972)2.63618231
32Constricted visual fields (HP:0001133)2.59782298
33Medial flaring of the eyebrow (HP:0010747)2.59775926
34Increased serum lactate (HP:0002151)2.57246262
35Septo-optic dysplasia (HP:0100842)2.47471258
36Abnormality of the renal cortex (HP:0011035)2.44391222
37Abnormal respiratory epithelium morphology (HP:0012253)2.39853537
38Abnormal respiratory motile cilium morphology (HP:0005938)2.39853537
39Colon cancer (HP:0003003)2.38605008
40Abolished electroretinogram (ERG) (HP:0000550)2.32182474
41Aplasia/Hypoplasia of the spleen (HP:0010451)2.31345133
42Increased intramyocellular lipid droplets (HP:0012240)2.30568831
43Decreased central vision (HP:0007663)2.27109413
44Abnormality of the renal medulla (HP:0100957)2.26824239
45Abnormal ciliary motility (HP:0012262)2.24706400
46Abnormality of the labia minora (HP:0012880)2.23222174
47Asplenia (HP:0001746)2.22551088
48Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.22423804
49Attenuation of retinal blood vessels (HP:0007843)2.21998483
50Gait imbalance (HP:0002141)2.21793136
51Methylmalonic acidemia (HP:0002912)2.21384342
52Congenital primary aphakia (HP:0007707)2.18497951
53Chronic hepatic failure (HP:0100626)2.18429391
54Absent thumb (HP:0009777)2.17727854
55Lactic acidosis (HP:0003128)2.17131103
56Cerebellar dysplasia (HP:0007033)2.15231980
57Keratoconus (HP:0000563)2.14816651
58Increased corneal curvature (HP:0100692)2.14816651
59Exertional dyspnea (HP:0002875)2.14283293
60Leukodystrophy (HP:0002415)2.13995906
61Optic nerve hypoplasia (HP:0000609)2.12858070
62Respiratory failure (HP:0002878)2.11767411
63Pallor (HP:0000980)2.11140904
64Nephrogenic diabetes insipidus (HP:0009806)2.09270433
65Abnormal respiratory motile cilium physiology (HP:0012261)2.07508991
66Bony spicule pigmentary retinopathy (HP:0007737)2.07347134
67Lissencephaly (HP:0001339)2.06608955
68Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.06158900
69Increased muscle lipid content (HP:0009058)2.05020394
70Abnormal hemoglobin (HP:0011902)2.03255913
71Renal cortical cysts (HP:0000803)2.02601297
72Hyperglycinemia (HP:0002154)2.01714434
73Sclerocornea (HP:0000647)2.01626965
74Cystic liver disease (HP:0006706)2.00417495
75Exercise intolerance (HP:0003546)1.99448518
76Tubular atrophy (HP:0000092)1.99103262
77Respiratory difficulties (HP:0002880)1.98459256
78Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.96722269
79Lethargy (HP:0001254)1.95627681
80Abnormal drinking behavior (HP:0030082)1.93971042
81Polydipsia (HP:0001959)1.93971042
82Methylmalonic aciduria (HP:0012120)1.91518727
83Abnormality of urine glucose concentration (HP:0011016)1.89018664
84Glycosuria (HP:0003076)1.89018664
85Abnormality of renal resorption (HP:0011038)1.88664428
86Postaxial foot polydactyly (HP:0001830)1.87857303
87Tubulointerstitial nephritis (HP:0001970)1.87589064
88Stenosis of the external auditory canal (HP:0000402)1.87092680
89Anencephaly (HP:0002323)1.85477332
90Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.82993247
91Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.82625884
92Decreased activity of mitochondrial respiratory chain (HP:0008972)1.82625884
93Abnormality of alanine metabolism (HP:0010916)1.82617748
94Hyperalaninemia (HP:0003348)1.82617748
95Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.82617748
96Congenital hepatic fibrosis (HP:0002612)1.80699375
97Supernumerary spleens (HP:0009799)1.80294357
98Aplasia/hypoplasia of the uterus (HP:0008684)1.79133106
99Triphalangeal thumb (HP:0001199)1.78437979
100Polyuria (HP:0000103)1.74517775

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K93.36422074
2TLK13.21189893
3ZAK3.02796030
4VRK22.80377594
5STK162.54599351
6GRK12.48530198
7WNK42.45804604
8NUAK12.39261938
9FRK2.25937115
10ADRBK22.21967924
11TAF12.05278330
12BMPR1B2.03277041
13TXK1.91939831
14TAOK31.85405362
15BUB11.82250098
16CASK1.81962595
17TRIM281.81929604
18TIE11.77993977
19DYRK21.73019289
20WNK31.70595980
21VRK11.66339675
22PRKD31.55836056
23TSSK61.50411742
24MARK11.48064598
25MAP4K21.46787854
26BCKDK1.44632729
27MAPK131.34531124
28PASK1.26839758
29NME11.12343784
30PLK31.08706091
31STK391.06696663
32CAMKK21.06317347
33CSNK1G31.04281906
34EIF2AK31.03328072
35SRPK11.01886707
36INSRR0.99593493
37PINK10.98476242
38CDK190.95682780
39LIMK10.94185017
40EIF2AK10.94177621
41TNK20.93265181
42PRKCG0.92050528
43CSNK1G20.89056037
44CSNK1A1L0.87893979
45OXSR10.87750477
46TNIK0.86171772
47CSNK1G10.84190546
48PRKCH0.82951989
49TEC0.79874620
50MAP2K60.78674986
51PLK10.78086054
52PAK30.77608497
53PDK20.71419526
54TGFBR10.71172302
55ADRBK10.67814712
56MST40.67189614
57AURKB0.66415896
58PRKCQ0.65529538
59PLK40.65502163
60NEK10.63308241
61CSNK2A20.62520611
62CDK80.62311887
63PHKG10.61800403
64PHKG20.61800403
65ATR0.59866297
66ITK0.59476952
67MAPKAPK50.59088979
68RPS6KA50.57652467
69CSNK1E0.54464884
70MINK10.54186428
71MAP3K40.54082259
72DAPK30.53051936
73AURKA0.52726581
74NTRK20.50725669
75PNCK0.50182251
76CSNK2A10.49938925
77CHEK20.49045702
78KDR0.48966024
79PRKACA0.48632014
80PRKCE0.47634710
81EPHA40.46890762
82MKNK20.44223206
83FES0.43491127
84MKNK10.43268967
85DAPK20.43069570
86PRKCI0.42922801
87EPHB20.42674619
88IKBKB0.41928589
89NEK20.41143091
90ATM0.40536372
91CSNK1A10.40032403
92MUSK0.39896958
93CAMKK10.39770804
94PKN10.39570158
95MAPK150.39191052
96MAP3K120.39056788
97PRKCA0.37999548
98PBK0.37726682
99RPS6KA60.36309618
100EIF2AK20.35883711

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.62674932
2Oxidative phosphorylation_Homo sapiens_hsa001904.12171926
3Parkinsons disease_Homo sapiens_hsa050123.37669155
4Proteasome_Homo sapiens_hsa030503.31043505
5Protein export_Homo sapiens_hsa030603.11339163
6Huntingtons disease_Homo sapiens_hsa050162.44235864
7Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.43638310
8RNA polymerase_Homo sapiens_hsa030202.40601075
9Alzheimers disease_Homo sapiens_hsa050102.25822226
10Basal transcription factors_Homo sapiens_hsa030222.14612169
11Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.07678234
12Homologous recombination_Homo sapiens_hsa034402.05167904
13Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.97301604
14Cardiac muscle contraction_Homo sapiens_hsa042601.86219947
15One carbon pool by folate_Homo sapiens_hsa006701.82457986
16Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.82364591
17RNA degradation_Homo sapiens_hsa030181.63803394
18Phototransduction_Homo sapiens_hsa047441.61582023
19Propanoate metabolism_Homo sapiens_hsa006401.61247561
20Linoleic acid metabolism_Homo sapiens_hsa005911.58113307
21Fanconi anemia pathway_Homo sapiens_hsa034601.56716245
22Asthma_Homo sapiens_hsa053101.53980603
23Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.50262536
24Maturity onset diabetes of the young_Homo sapiens_hsa049501.41602501
25Butanoate metabolism_Homo sapiens_hsa006501.37384277
26Intestinal immune network for IgA production_Homo sapiens_hsa046721.37197332
27Mismatch repair_Homo sapiens_hsa034301.30065895
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.29316396
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.24153538
30Base excision repair_Homo sapiens_hsa034101.21939755
31Peroxisome_Homo sapiens_hsa041461.15053094
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.11861061
33Allograft rejection_Homo sapiens_hsa053301.11690273
34Pyrimidine metabolism_Homo sapiens_hsa002401.10375521
35Sulfur relay system_Homo sapiens_hsa041221.09858309
36Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.06288407
37Tryptophan metabolism_Homo sapiens_hsa003801.03965698
38RNA transport_Homo sapiens_hsa030131.03792866
39Nucleotide excision repair_Homo sapiens_hsa034201.02459870
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.02041532
41Sulfur metabolism_Homo sapiens_hsa009201.01115272
42Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.00532475
43Primary immunodeficiency_Homo sapiens_hsa053401.00397108
44Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.98924891
45Spliceosome_Homo sapiens_hsa030400.97121933
46DNA replication_Homo sapiens_hsa030300.97101525
47Autoimmune thyroid disease_Homo sapiens_hsa053200.96273887
48Purine metabolism_Homo sapiens_hsa002300.93072602
49Nitrogen metabolism_Homo sapiens_hsa009100.91729620
50Type I diabetes mellitus_Homo sapiens_hsa049400.90431679
51Regulation of autophagy_Homo sapiens_hsa041400.87766151
52Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.83309974
53Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.82467980
54Chemical carcinogenesis_Homo sapiens_hsa052040.81964937
55Selenocompound metabolism_Homo sapiens_hsa004500.81002846
56Ether lipid metabolism_Homo sapiens_hsa005650.79954011
57Cysteine and methionine metabolism_Homo sapiens_hsa002700.78868221
58Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.78700609
59Fat digestion and absorption_Homo sapiens_hsa049750.78502318
60Collecting duct acid secretion_Homo sapiens_hsa049660.75179261
61Caffeine metabolism_Homo sapiens_hsa002320.74893363
62Metabolic pathways_Homo sapiens_hsa011000.74038294
63Graft-versus-host disease_Homo sapiens_hsa053320.71835692
64Non-homologous end-joining_Homo sapiens_hsa034500.71619370
65Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71610384
66Nicotine addiction_Homo sapiens_hsa050330.71345778
67Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70285063
68Arachidonic acid metabolism_Homo sapiens_hsa005900.67870869
69Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.67002949
70Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.66203355
71Folate biosynthesis_Homo sapiens_hsa007900.62044190
72Retinol metabolism_Homo sapiens_hsa008300.60001193
73Steroid hormone biosynthesis_Homo sapiens_hsa001400.58677375
74Olfactory transduction_Homo sapiens_hsa047400.58512605
75Taste transduction_Homo sapiens_hsa047420.54889300
76Hematopoietic cell lineage_Homo sapiens_hsa046400.54881568
77Pyruvate metabolism_Homo sapiens_hsa006200.53147147
78Pentose and glucuronate interconversions_Homo sapiens_hsa000400.52827841
79Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.51516570
80Steroid biosynthesis_Homo sapiens_hsa001000.50229869
81Rheumatoid arthritis_Homo sapiens_hsa053230.49964874
82Primary bile acid biosynthesis_Homo sapiens_hsa001200.49484593
83Fatty acid degradation_Homo sapiens_hsa000710.49034518
84Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.48537449
85Cyanoamino acid metabolism_Homo sapiens_hsa004600.48106018
86beta-Alanine metabolism_Homo sapiens_hsa004100.47695230
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.45556250
88Vitamin digestion and absorption_Homo sapiens_hsa049770.44831739
89Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44556532
90Ovarian steroidogenesis_Homo sapiens_hsa049130.39507659
91Hedgehog signaling pathway_Homo sapiens_hsa043400.38604964
92Glycerolipid metabolism_Homo sapiens_hsa005610.36824093
93Fatty acid elongation_Homo sapiens_hsa000620.33904084
94Antigen processing and presentation_Homo sapiens_hsa046120.33749070
95Drug metabolism - other enzymes_Homo sapiens_hsa009830.31574287
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.30270381
97Basal cell carcinoma_Homo sapiens_hsa052170.29037563
98Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.27813562
99Morphine addiction_Homo sapiens_hsa050320.24531393
100Systemic lupus erythematosus_Homo sapiens_hsa053220.24284674

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »